CN218792620U

CN218792620U - Mouse perfusion device for preventing air injection

Info

Publication number: CN218792620U
Application number: CN202221896166.2U
Authority: CN
Inventors: 沈璐; 潘永良; 牟秋月; 吴宾鸿; 丁宇雯
Original assignee: Huzhou University
Current assignee: Huzhou University
Priority date: 2022-07-22
Filing date: 2022-07-22
Publication date: 2023-04-07
Anticipated expiration: 2032-07-22

Abstract

The utility model discloses a prevent mouse perfusion device of air injection relates to perfusion device technical field, and the three-way pipe is installed to the one end of filling the conveyer pipe, the normal saline conveyer pipe is installed to an end in two other of three-way pipe, and the stationary liquid conveyer pipe is installed to another end in two other of three-way pipe, all be provided with the metering valve on normal saline conveyer pipe and the stationary liquid conveyer pipe, through utilizing the three-way pipe to fill conveyer pipe, normal saline conveyer pipe and stationary liquid duct linkage together, which kind of solution is needed, only need open the metering valve on corresponding solution conveyer pipe, can not have the cavity to get into in filling the conveyer pipe, will fill the conveyer pipe and divide into and be responsible for and the auxiliary pipe, be responsible for the elasticity and reduce the back, can screw down the person in charge, change brand-new person in charge, need not change whole device, install the check valve simultaneously on the auxiliary pipe and prevent to fill the solution backward flow pollution normal saline conveyer pipe and the stationary liquid conveyer pipe in the conveyer pipe.

Description

Mouse perfusion device for preventing air injection

Technical Field

The utility model relates to a perfusion device technical field specifically is a mouse perfusion device who prevents air injection.

Background

The mouse heart perfusion technology needs to utilize a mouse perfusion device, for example, a patent net discloses a novel experimental large mouse heart precise perfusion device (publication number: CN 214629462U), the perfusion device firstly injects physiological saline, a connecting hose is connected with a conveying pipe of the physiological saline, then a fixing liquid is input, an original physiological saline pipe is detached from the connecting hose, the conveying pipe of the fixing liquid is connected to the connecting hose, and in the process, air enters the connecting hose to influence the whole experiment.

SUMMERY OF THE UTILITY MODEL

The utility model provides a mouse perfusion device for preventing air injection has solved and has torn original normal saline pipe down from coupling hose, receives coupling hose to fixed liquid conveying pipe again and has had air admission coupling hose's problem.

In order to achieve the above purpose, the utility model discloses a following technical scheme realizes: the mouse perfusion device for preventing air injection comprises a perfusion conveying pipe, wherein a three-way pipe is installed at one end of the perfusion conveying pipe, a normal saline conveying pipe is installed at one end of the other two of the three-way pipe, a fixing liquid conveying pipe is installed at the other end of the other two of the three-way pipe, and metering valves are arranged on the normal saline conveying pipe and the fixing liquid conveying pipe.

As a further technical proposal of the utility model, the other end of the perfusion conveying pipe is provided with a puncture needle, and the needle head of the puncture needle is sleeved with a needle sleeve.

As a further technical scheme of the utility model, fill the conveyer pipe including being responsible for, be responsible for the side and be provided with the auxiliary line.

As a further technical scheme of the utility model, female connector is installed to the one end of being responsible for, the outer thread connection head with female connector looks adaptation is installed to the one end of auxiliary pipe.

As a further technical scheme of the utility model, be provided with the check valve on the auxiliary pipe, the material of being responsible for and auxiliary pipe is the same with the size.

As a further technical scheme of the utility model, be provided with the peristaltic pump on filling the conveyer pipe, the material and the size of normal saline conveyer pipe and stationary liquid conveyer pipe are the same.

Advantageous effects

The utility model provides a mouse perfusion device for preventing air injection. Compared with the prior art, the method has the following beneficial effects:

1. the utility model provides a prevent mouse perfusion device of air injection, through utilizing the three-way pipe to filling the conveyer pipe, normal saline conveyer pipe and stationary liquid conveyer pipe link together, which kind of solution is required, only need open the metering valve on corresponding solution conveyer pipe, thereby make and fill the conveyer pipe and switch on with corresponding solution conveyer pipe, only need open the metering valve that needs solution simultaneously when solution is carried in the transform, and close another, can not have the cavity to get into in filling the conveyer pipe, avoid the air admission to fill the conveyer pipe and influence whole experiment.

2. The utility model provides a prevent air injection's mouse perfusion device, the peristaltic pump can destroy the elasticity of filling the conveyer pipe when peristaltic to filling the conveyer pipe, elasticity descends and can lead to the peristaltic pump to carry the effect to reduce, this device will fill the conveyer pipe and divide into and be responsible for and the auxiliary pipe, the two utilizes external screw thread connector and female connector to connect, be responsible for and put elasticity reduction back on the peristaltic pump, can with being responsible for and revolve down, change brand-new being responsible for, need not change whole device, the waste of resource has been reduced, install the check valve simultaneously on the auxiliary pipe and prevent to fill solution backward flow in the conveyer pipe and pollute normal saline conveyer pipe and stationary liquid conveyer pipe.

Drawings

FIG. 1 is a schematic view of a mouse perfusion apparatus for preventing air injection;

FIG. 2 is a side view of a mouse perfusion apparatus preventing air injection;

FIG. 3 is an exploded view of the perfusion delivery tube of a mouse perfusion apparatus that prevents air injection.

In the figure: 1. filling a delivery pipe; 101. a main pipe; 102. a secondary pipe; 103. an internal thread connector; 104. an external thread connector; 105. a one-way valve; 2. a three-way pipe; 3. a physiological saline delivery pipe; 4. fixing the liquid conveying pipe; 5. a metering valve; 6. puncturing needle; 7. a needle sleeve; 8. a peristaltic pump.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-2, the present invention provides a technical solution of a mouse perfusion device for preventing air injection: the utility model provides a mouse perfusion device for preventing air injection, including filling conveyer pipe 1, three-way pipe 2 is installed to the one end of filling conveyer pipe 1, normal saline conveyer pipe 3 is installed to an end in two other of three-way pipe 2, stationary liquid conveyer pipe 4 is installed to another end in two other of three-way pipe 2, all be provided with metering valve 5 on normal saline conveyer pipe 3 and the stationary liquid conveyer pipe 4, the material and the size of normal saline conveyer pipe 3 and stationary liquid conveyer pipe 4 are the same, in using, be connected normal saline conveyer pipe 3 and normal saline supply device, be connected stationary liquid conveyer pipe 4 and stationary liquid supply device, when needing to use normal saline, open metering valve 5 on the normal saline conveyer pipe 3, thereby make normal saline conveyer pipe 3 switch on, normal saline supply device gets into normal saline from normal saline conveyer pipe 3 in filling conveyer pipe 1, when getting into the mouse heart, when needing stationary liquid, close metering valve 5 on normal saline conveyer pipe 3 and open metering valve 5 on stationary liquid conveyer pipe 4, stationary liquid conveyer pipe 4 switches on, stationary liquid supply device sends stationary liquid into the interior through the conveyer pipe 1 of mouse from stationary liquid 4, can not get into the empty chamber entering experiment of mouse, avoid whole heart to get into the experiment 1 of air infusion from the conveyer pipe, 1.

Referring to fig. 3, the filling and conveying pipe 1 includes a main pipe 101, a secondary pipe 102 is arranged on the side surface of the main pipe 101, an internal thread connector 103 is arranged at one end of the main pipe 101, an external thread connector 104 matched with the internal thread connector 103 is arranged at one end of the secondary pipe 102, a check valve 105 is arranged on the secondary pipe 102, the main pipe 101 and the secondary pipe 102 are made of the same material and have the same size, if the main pipe 101 of the filling and conveying pipe 1 works on the peristaltic pump 8 for a long time and the elasticity is reduced, the internal thread connector 103 can be rotated to separate the main pipe 101 from the secondary pipe 102, and then the brand new internal thread connector 103 of the main pipe 101 is screwed on the external thread connector 104 of the secondary pipe 102 to form a new filling and conveying pipe 1, the whole pipeline does not need to be scrapped, and the waste of resources is reduced.

Referring to fig. 1-3, a peristaltic pump 8 is disposed on the perfusion tube 1, a puncture needle 6 is mounted at the other end of the perfusion tube 1, a needle cover 7 is sleeved on a needle head of the puncture needle 6, and the peristaltic pump 8 drives the solution inside the perfusion tube 1 to advance by peristalsis.

The utility model discloses a theory of operation: when the device is used, the needle sleeve 7 is pulled out, the puncture needle 6 is inserted into the heart of a mouse, the physiological saline conveying pipe 3 is connected with a physiological saline supply device, the stationary fluid conveying pipe 4 is connected with the stationary fluid supply device, when the physiological saline is needed to be used, the metering valve 5 on the physiological saline conveying pipe 3 is opened, so that the physiological saline conveying pipe 3 is conducted, the physiological saline enters the perfusion conveying pipe 1 from the physiological saline conveying pipe 3 by the physiological saline supply device, when the physiological saline enters the heart of the mouse, the metering valve 5 on the physiological saline conveying pipe 3 is closed and the metering valve 5 on the stationary fluid conveying pipe 4 is opened when the stationary fluid is needed, the stationary fluid conveying pipe 4 is conducted, the stationary fluid is conveyed into the heart of the mouse from the stationary fluid conveying pipe 4 through the perfusion conveying pipe 1 by the stationary fluid supply device, no cavity enters the perfusion conveying pipe 1, meanwhile, the metering valve 5 can display the flow of the solution passing through the conveying pipe in real time, and enable a user to better control the input amount of the solution;

if the main pipe 101 of the perfusion conveying pipe 1 works on the peristaltic pump 8 for a long time and the elasticity is reduced, the perfusion conveying pipe 1 is taken down from the peristaltic pump 8, the main pipe 101 is separated from the auxiliary pipe 102 by rotating the internal thread connector 103, and then the brand-new internal thread connector 103 of the main pipe 101 is screwed on the external thread connector 104 of the auxiliary pipe 102 to form a new perfusion conveying pipe 1 without scrapping the whole pipeline.

Claims

1. The utility model provides a mouse perfusion device who prevents air injection, is including filling conveyer pipe (1), its characterized in that, three-way pipe (2) are installed to the one end of filling conveyer pipe (1), normal saline conveyer pipe (3) are installed to one end in the other two of three-way pipe (2), fixed liquid conveyer pipe (4) are installed to another end in the other two of three-way pipe (2), all be provided with metering valve (5) on normal saline conveyer pipe (3) and fixed liquid conveyer pipe (4).

2. The air injection prevention mouse perfusion device according to claim 1, wherein the other end of the perfusion delivery pipe (1) is provided with a puncture needle (6), and the needle head of the puncture needle (6) is sleeved with a needle sleeve (7).

3. The air injection prevention mouse perfusion device according to claim 1, wherein the perfusion delivery tube (1) comprises a main tube (101), and a secondary tube (102) is arranged on the side of the main tube (101).

4. The mouse perfusion device for preventing air injection according to claim 3, wherein an internal threaded connector (103) is installed at one end of the main pipe (101), and an external threaded connector (104) matched with the internal threaded connector (103) is installed at one end of the auxiliary pipe (102).

5. The mouse perfusion device preventing air injection according to claim 3, wherein the secondary tube (102) is provided with a one-way valve (105), and the main tube (101) and the secondary tube (102) are made of the same material and have the same size.

6. The mouse perfusion device preventing air injection according to claim 1, wherein the perfusion delivery pipe (1) is provided with a peristaltic pump (8), and the physiological saline delivery pipe (3) and the stationary liquid delivery pipe (4) are made of the same material and have the same size.