CN218516001U - Electrode patch for tumor therapy - Google Patents

Abstract

The utility model provides an electrode patch for tumor therapy, wherein an electrode slice is arranged in a positioning hole of a foam pad; the electrode plate comprises an insulated electrode and a reinforcing sheet which are identical in shape and are mutually bonded and connected, and the flexible circuit board is positioned between the insulated electrode and the reinforcing sheet and is welded and connected with the insulated electrode; the side, facing the reinforcing sheet, of the non-woven fabric base layer is provided with an adhesive layer, the outline shape of the adhesive layer is the same as that of the non-woven fabric base layer, and the adhesive layer is also provided with abdicating holes in the same shape as that of the reinforcing sheet; the non-woven fabric base layer is provided with a first air hole, the adhesive layer is provided with a second air hole, and the first air hole is communicated with the second air hole; the conductive gel is applied to the surfaces of the foam pad and the insulated electrode. Through first bleeder vent and the second bleeder vent that communicates each other, make things convenient for skin to breathe freely, reduce the sweat and produce, prolong the life on viscose layer, make the viscose layer not paste in the reinforcement piece through the hole of stepping down, realize split type change, reduce use cost.

Description

Electrode patch for tumor therapy

Technical Field

The specification relates to the technical field of medical equipment, in particular to an electrode patch for tumor therapy.

Background

Glioblastoma multiforme (GBM) is the most malignant of the primary brain tumors. Tumor-treating electric field (TTF) is an alternating electric field with frequency of 100-300kHz and electric field intensity less than 2V/cm, and is a new method for treating GBM. TTF can selectively interfere with normal mitosis of cells, extending survival in GBM patients.

TTF delivers therapeutic electrical energy through a set of medical equipment consisting of an electric field generator, an electrode patch, a power supply, and a control device. In the treatment process, the electrode patch is required to be attached to the skin of a focus area of a patient, a plurality of electrodes are arranged in the electrode patch, a low-intensity medium-frequency alternating electric field is generated, and the electric field force is conducted into the body of the patient. However, the current electrode patch is not good in air permeability, and the electrode patch is likely to cause skin sweating during discharging, thereby causing irritant dermatitis or contact dermatitis. In addition, the electrode patch is pasted on the skin through the adhesive layer, after the electrode patch is used for multiple times, particularly in warm and humid seasons, the pasting force can be worsened, the pasting effect is influenced, the treatment effect is influenced, and the electrode patch is of an integrated structure, so that the whole replacement price is high.

SUMMERY OF THE UTILITY MODEL

In view of this, the utility model provides an electrode patch for tumor therapy has the ventilative layer that air permeability is good, has good perspire ability, reduces the dermatitis and takes place to can divide the body to change, reduce use cost.

The embodiment of the utility model provides a following technical scheme:

an electrode patch for tumor therapy, comprising: the flexible circuit board comprises a non-woven fabric base layer, an adhesive layer, a flexible circuit board, a foam pad, a plurality of electrode plates and conductive gel;

a positioning hole is formed in the foam pad, and the electrode plate is correspondingly arranged in the positioning hole;

the electrode plate comprises an insulated electrode and a reinforcing sheet which are identical in shape and are mutually bonded, the flexible circuit board is welded with the insulated electrode and is positioned between the insulated electrode and the reinforcing sheet, and the reinforcing sheet is fixedly arranged on the flexible circuit board;

the side, facing the reinforcing sheet, of the non-woven fabric base layer is provided with the adhesive layer, the outline shape of the adhesive layer is the same as that of the non-woven fabric base layer, the adhesive layer is further provided with abdicating holes, and the shapes of the abdicating holes are the same as those of the reinforcing sheet;

the non-woven fabric base layer is provided with a first air hole, the adhesive layer is provided with a second air hole, and the first air hole is communicated with the second air hole;

the conductive gel is applied to the surfaces of the foam pad and the insulated electrode.

In the above scheme, non-woven fabric basic unit and viscose layer are provided with first bleeder vent and second bleeder vent respectively, and the viscose layer is directly pasted on human skin, through first bleeder vent and the second bleeder vent of intercommunication each other, make things convenient for skin to breathe freely, reduce the sweat and produce, and simultaneously, the viscose layer still is provided with the hole of stepping down, the shape in hole of stepping down is the same with the profile shape of reinforcement piece for the viscose layer is not pasted in the reinforcement piece, on the non-stick electrode piece structure promptly, when needing to be changed non-woven fabric basic unit, non-woven fabric basic unit and viscose layer can conveniently separate with the reinforcement piece, and all the other devices and structure are not influenced, and this dismantlement substitution mode can only the non-woven fabric basic unit and the viscose layer that the cost is lower relatively, realizes split type change, thereby reduce use cost.

The utility model also provides a scheme, the shape of first bleeder vent includes cylindrically.

The utility model also provides a proposal that the second air holes comprise a first section close to the reinforcing sheet and a second section close to the non-woven fabric base layer;

the shape of the first section comprises a cylinder;

and/or, the shape of the second section comprises a trumpet shape.

The utility model also provides a scheme, the electrode paster is used in tumour therapy still includes the sweat-absorbing layer of being made by fiber material, the mounting hole has been seted up on the sweat-absorbing layer, the foam pad set up in the mounting hole.

The utility model also provides a scheme, the material of insulated electrode includes piezoceramics material, piezoceramics material's dielectric constant when 200kHz is 5336 ~ 6264, and dielectric loss is not more than 15%.

The utility model also provides a scheme, the shape of insulated electrode includes circularly.

The utility model also provides a scheme, the center of insulated electrode is provided with the through-hole, be provided with the temperature probe in the through-hole.

The utility model also provides a scheme, the insulated electrode orientation one side of reinforcement piece is provided with annular silvered film, annular silvered film's thickness is 0.005 ~ 0.01mm.

The utility model also provides a scheme, the resistance between arbitrary two points of interval 10mm on the electrically conductive gel is less than 8000 ohm.

The utility model also provides a scheme, the foam pad orientation electrically conductive gel one side is provided with the acrylic acid double faced adhesive tape.

Compared with the prior art, the utility model discloses an above-mentioned at least one technical scheme beneficial effect that can reach includes at least: the electrode slice comprises an insulated electrode and a reinforcing sheet which are in the same shape and are in adhesive connection with each other, the flexible circuit board is welded on the insulated electrode and is positioned between the insulated electrode and the reinforcing sheet, the electrode slice is positioned in a positioning hole in the foam pad, the non-woven fabric base layer is provided with an adhesive layer towards one side of the reinforcing sheet, the outline shape of the adhesive layer is the same as that of the non-woven fabric base layer, the adhesive layer is also provided with a yielding hole, the shape of the yielding hole is the same as that of the reinforcing sheet, the non-woven fabric base layer is also provided with a first air hole, the adhesive layer is provided with a second air hole, the first air hole is communicated with the second air hole, the conductive coating is coated on the surface of the foam pad and the insulated electrode, and the first air hole and the second air hole are respectively arranged on the non-woven fabric base layer and the adhesive layer, the viscose layer is directly pasted on human skin, first bleeder vent and second bleeder vent communicate each other, can do benefit to skin and breathe freely, reduce the sweat and produce, improve and use the impression, maintain the viscidity on viscose layer, the increase of service life, furthermore, the viscose layer still is provided with the hole of stepping down, the shape in hole of stepping down is the same with the profile shape of reinforcement piece, when the installation, the viscose layer does not bond the reinforcement piece, when the non-woven fabrics basic unit is changed to needs, non-woven fabrics basic unit and viscose layer can conveniently separate with the reinforcement piece, all the other devices and the mounting structure of electrode paster are not influenced, this dismantlement substitution mode can only the non-woven fabrics basic unit and the viscose layer that replacement cost is lower relatively, realize split type change, can reduce use cost.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.

FIG. 1 is an exploded view of an electrode patch for tumor therapy;

FIG. 2 is a schematic cross-sectional view of an adhesive layer and a nonwoven substrate;

FIG. 3 is a schematic top view of an electrode patch for oncology therapy;

FIG. 4 is a schematic cross-sectional view of an insulated electrode;

100, a sweat absorbing layer, 101, a foam pad, 102, conductive gel, 103, an insulating ceramic sheet, 104, a flexible circuit board, 105, an adhesive layer, 106, a non-woven fabric base layer, 107 and a thermistor.

Detailed Description

The embodiments of the present application will be described in detail below with reference to the accompanying drawings.

The following description of the embodiments of the present application is provided by way of specific examples, and other advantages and effects of the present application will be readily apparent to those skilled in the art from the disclosure herein. It is to be understood that the embodiments described are only a few embodiments of the present application and not all embodiments. The application is capable of other and different embodiments and its several details are capable of modifications and various changes in detail without departing from the spirit of the application. It is to be noted that the features in the following embodiments and examples may be combined with each other without conflict. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

It is noted that various aspects of the embodiments are described below within the scope of the appended claims. It should be apparent that the aspects described herein may be embodied in a wide variety of forms and that any specific structure and/or function described herein is merely illustrative. Based on the present application, one skilled in the art should appreciate that one aspect described herein may be implemented independently of any other aspects and that two or more of these aspects may be combined in various ways. For example, an apparatus may be implemented and/or a method practiced using any number and aspects set forth herein. Additionally, such an apparatus may be implemented and/or such a method may be practiced using other structure and/or functionality in addition to one or more of the aspects set forth herein.

It should be noted that the drawings provided in the following embodiments are only for illustrating the basic idea of the present application, and the drawings only show the components related to the present application rather than the number, shape and size of the components in actual implementation, and the type, amount and ratio of the components in actual implementation may be changed arbitrarily, and the layout of the components may be more complicated.

It is to be understood that "the component a is connected to the component B" means that the component a is directly connected to the component B in contact therewith, or the component a is indirectly connected to the component B through other components. The terms of orientation of "upper", "lower", "inner", "outer", "side", and the like described in the exemplary embodiments of the present specification are described with respect to the angles shown in the drawings, and should not be construed as limiting the exemplary embodiments of the present specification.

In addition, in the following description, specific details are provided to facilitate a thorough understanding of the examples. However, it will be understood by those skilled in the art that the aspects may be practiced without these specific details.

Glioblastoma multiforme (GBM) is the most malignant of the primary brain tumors. The tumor treating electric field (TTF) is one kind of alternating electric field with frequency of 100-300kHz and electric field strength lower than 2V/cm, and is one non-invasive method of treating glioma. TTF can selectively interfere with normal mitosis of cells, and preclinical studies have shown that TTF has antimitotic effects on various tumors and can prolong survival of GBM patients, and newly diagnosed and relapsed GBM patients are approved by the U.S. food and drug administration for treatment with TTF after receiving surgery and radiotherapy with temozolomide as an adjuvant. In addition, due to novel form, remarkable curative effect and few adverse reactions of TTF, TTF is recommended to be used for treatment of new GBM (grade 1 evidence) and recurrent high-grade brain glioma (grade 2 evidence) in brain glioma diagnosis and treatment specifications issued by the national health committee of 12 months in 2018.

TTF passes through the electric energy of a set of medical equipment conveying treatment, and this equipment comprises electric field generator, electric field paster, power and controlling means, in the treatment process, needs to paste the electrode paster on the skin of patient's focus region, is provided with a plurality of electrodes in the electrode paster, produces low-strength intermediate frequency alternating electric field, through leading electric field power to patient's internal. However, due to the problems of the structural design and materials of the electrode patch, the current electrode patch has poor air permeability, and the electrode patch is easy to cause skin sweating during the discharging process, thereby causing irritant dermatitis or contact dermatitis. In addition, the electrode patch is pasted on the skin through the adhesive layer, after the electrode patch is used for multiple times, particularly in warm and humid seasons, the pasting force can be worsened, the pasting effect is influenced, if the electrode cannot be well attached to the skin of a human body, the treatment effect can be influenced, and the electrode patch is of an integrated structure, so that the price of overall replacement is high when the adhesion of the patch is insufficient.

The utility model provides an electrode paster for oncologic treatment sets up first bleeder vent and second bleeder vent in viscose layer and non-woven fabrics basic unit respectively, and make intercommunication each other between two sets of bleeder vents, thereby can improve the ventilation effect among the treatment process, improve the shape on viscose layer simultaneously, design hollow out construction's hole of stepping down on viscose layer, dodge the electrode, make the electrode can not bond in viscose layer, when needs change viscose layer and non-woven fabrics basic unit, be convenient for the two breaks away from the electrode, realize the components of a whole that can function independently and change.

The technical solutions provided by the embodiments of the present application are described below with reference to the accompanying drawings.

As shown in fig. 1 to 4, an electrode patch for tumor therapy is a multi-layer structure, and as shown in fig. 1, the multi-layer structure sequentially includes: a non-woven fabric base layer 106, an adhesive layer 105, a flexible circuit board 104, a foam pad 101, a plurality of electrode pads, and a conductive gel 102.

The foam pad 101 is provided with positioning holes with the same number as the electrode plates, and the electrode plates are correspondingly arranged in the positioning holes; it should be noted that, the number of the positioning holes may also be less than that of the electrode plates, and a plurality of electrode plates are commonly disposed in the same positioning hole.

The electrode plate comprises an insulated electrode and a reinforcing sheet, the insulated electrode and the reinforcing sheet are identical in shape and are connected in a bonding mode, the reinforcing sheet is fixedly arranged on the flexible circuit board 104, the flexible circuit board 104 is located on the insulated electrode and located between the insulated electrode and the reinforcing sheet, and the flexible circuit board 104 is welded with the insulated electrode. The insulated electrode may employ an insulated ceramic sheet 103 as in fig. 1.

Non-woven fabrics base layer 106 orientation reinforcement piece one side is provided with viscose layer 105, and the profile shape of viscose layer 105 is the same with the profile shape of non-woven fabrics base layer 106 to can form good adhesive connection with non-woven fabrics base layer 106, and viscose layer 105 has still seted up the hole of stepping down, the shape in hole of stepping down is the same with the profile shape of the reinforcement piece of electrode slice, and the reinforcement piece is located the electrode slice towards one side of non-woven fabrics base layer 106, owing to seted up the hole of stepping down at viscose layer 105, the reinforcement piece can not bond on non-woven fabrics base layer 106.

As shown in fig. 2, the non-woven fabric substrate 106 is provided with a first air hole, and the adhesive layer 105 is provided with a second air hole, wherein the first air hole is communicated with the second air hole.

The conductive gel 102 is applied to the surfaces of the foam pad 101 and the insulated electrodes.

Through first bleeder vent and the second bleeder vent of intercommunication each other, make things convenient for skin to breathe freely, reduce sweat and produce to set up the hole of stepping down at the viscose layer, make the electrode slice not bond on non-woven fabrics basic unit 106, realize split type change when changing, reduce use cost.

In other embodiments, the material of the reinforcing sheet is glass fiber epoxy resin material. Preferably, the reinforcing sheet is made of an FR4 glass fiber epoxy resin copper-clad plate.

In some embodiments, as shown in fig. 2, the first vent is cylindrical in shape.

Preferably, the diameter of the cylindrical first air hole is 1.6-1.8 mm.

It should be noted that, in the nonwoven fabric substrate 106, the cylindrical first vents may be uniformly formed in one diameter specification, or may be formed in different positions in different diameter specifications.

In some embodiments, as shown in FIG. 2, the second vent comprises a first section adjacent to the reinforcing panel and a second section adjacent to the nonwoven substrate 106, wherein the first section is cylindrical in shape.

Preferably, the diameter of the cylindrical first section is 1.6 to 2mm. The cylindrical first section can be uniformly provided with one diameter specification, and can also be provided with different diameter specifications at different positions.

In some embodiments, as shown in fig. 2, the second section is flared in shape.

Preferably, the diameter of the large end of the flared second section is 2.5 to 3mm. The flared second section can be uniformly provided with one diameter specification, and can also be provided with different diameter specifications at different positions.

Through setting up tubaeform structure, can provide the exhaust effect that can be better.

It should be noted that the cylindrical first section may be omitted, and the small end of the flared second section may be located on the end surface of the adhesive layer 105 on the side close to the reinforcing sheet.

In some embodiments, as shown in fig. 1, the electrode patch for tumor therapy further includes a sweat absorbing layer 100 made of a fiber material, the sweat absorbing layer 100 having a mounting hole into which a foam pad 101 is disposed.

The sweat absorbing layer is arranged on one side close to the skin of a human body, sweat can be absorbed, and the adhesive layer 105, the non-woven fabric base layer 106, the electrode plates and the flexible circuit board 104 are dry.

Preferably, the sweat-absorbent layer 100 has a thickness of 1.5 to 1.7mm.

Preferably, the sweat-absorbing layer 100 has a length of 125 to 130mm and a width of 80 to 85mm.

Preferably, the length of the mounting hole is 70 to 75mm, and the width is 25 to 26mm.

In some embodiments, the material of the insulated electrode comprises a piezoceramic material having a dielectric constant of 5336-6264 at 200kHz and a dielectric loss of no more than 15%.

In some embodiments, the insulated electrode is circular in shape.

Preferably, the diameter of the circular insulated electrode is 22 to 23mm, and the thickness is 1.3 to 1.4mm.

The shape of the insulated electrode may be a regular polygon.

In some embodiments, as shown in fig. 3, the center of the insulated electrode is provided with a through hole, and a temperature probe is arranged in the through hole, and the temperature probe can adopt a thermistor 107 or a thermocouple.

It should be noted that the temperature measuring probe can be designed at a reasonable position according to actual use, and the temperature measuring probe does not need to be installed in each through hole.

Preferably, the diameter of the through hole is 4-4.5 mm.

In some embodiments, as shown in fig. 4, the side of the insulated electrode facing the reinforcing sheet is provided with an annular silver plating layer having a thickness of 0.005 to 0.01mm.

Preferably, the diameter of the outer circle of the annular silver plating layer is 18-18.5 mm, and the diameter of the inner circle of the annular silver plating layer is 3-3.5 mm.

In some embodiments, the resistance between any two points on the conductive gel 102 spaced 10mm apart is less than 8000 ohms.

In some embodiments, the foam pad is provided with an acrylic double-sided tape on the side facing the conductive gel 102.

By providing acrylic double-sided tape, installation and replacement of the conductive gel 102 is facilitated.

[ example 1 ]

As shown in the electrode patch for tumor therapy of fig. 1 to 4, the electrode sheet is formed by welding the silver-plated surface of the insulated electrode and the flexible circuit board 104. In this embodiment, the insulated electrode is made of Tao Yadian ceramic material, such as the insulated ceramic plate 103 in fig. 1, and the insulated electrode is circular, with a diameter of 22-23 mm, a thickness of 1.3-1.4 mm, and a middle circular hole with a diameter of 4-4.5 mm. The insulating ceramic sheet 103 generates a capacitance or displacement current when a current inducing an electric field is applied, instead of a conventional charge transfer to the current. The back of the flexible circuit board 104 is provided with a reinforcing sheet made of FR4 glass fiber epoxy resin copper clad plate material, so that the defects of low rigidity and strength and easy breakage of ceramic materials are overcome.

The middle position of the insulated electrode is provided with a circular through hole, the thermistor 107 is welded on the through hole, and the thermistor 107 is welded with the flexible circuit board 104. In this embodiment, the electrode pieces are arranged in a rectangular array, the number of the electrode pieces is nine, and the flexible circuit board 104 is provided with a connecting line for connecting the high-frequency input line of the insulated electrode, the control line of the thermistor 107, and the common ground line of the thermistor. By arranging the thermistor 107, the temperature of the insulated electrode 103 can be monitored in real time, and the current can be timely adjusted when the temperature is abnormal, so that the treatment safety and quality effect are ensured.

The surfaces of the foam pad 101 and the insulated electrode are coated with the conductive gel 102, the resistance values of two points of 10mm of the foam pad and the insulated electrode are less than 8000 ohm, the foam pad is high in conductivity and viscous and has long-time biocompatibility, and the viscosity and the conductive effect of treatment time are guaranteed. The conductive gel 102 may also be coated prior to treatment.

The position department at flexible circuit board position 104 of viscose layer 105, the position department at reinforcement piece place promptly is provided with the hole of stepping down, and the shape in hole of stepping down is the same with the profile shape of reinforcement piece to make the reinforcement piece can not bond on viscose layer 105. The adhesive layer 105 is provided with a second air hole, wherein one side close to the skin is a cylindrical air hole with the diameter of 1.6-2 mm; one side facing the non-woven fabric base layer 106 is provided with a trumpet-shaped air hole, and the diameter of the trumpet Kong Daduan is 2.5-3 mm. The size of the outer contour of the adhesive layer 105 is consistent with the size of the non-woven fabric base layer 106. The flexible circuit board 104 is located at the center of the entire tumor therapy electrode patch.

The sweat absorbing layer 100 is made of fiber materials, specifically, can be made of a mixed material of polyester fibers and plant fibers, and has the following external dimensions: length 125-130 mm, width: 80-85 mm, thickness is 1.5-1.7 mm, and inside is equipped with the mounting hole of rectangle for install foam pad 101, the size of mounting hole is: the length is 70-75 mm, and the width is 25-26 mm.

The embodiments in the present specification are described in a progressive manner, and the same and similar parts among the embodiments can be referred to each other, and each embodiment focuses on the differences from the other embodiments. In particular, for the method embodiments described later, since they correspond to the system, the description is simple, and for the relevant points, reference may be made to the partial description of the system embodiments.

The above description is only for the specific embodiments of the present application, but the scope of the present application is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present application should be covered within the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims (10)

1. An electrode patch for tumor therapy, characterized by comprising: the flexible circuit board comprises a non-woven fabric base layer, an adhesive layer, a flexible circuit board, a foam pad, a plurality of electrode plates and conductive gel;

a positioning hole is formed in the foam pad, and the electrode plate is correspondingly arranged in the positioning hole;

the electrode plate comprises an insulated electrode and a reinforcing sheet which are identical in shape and are mutually bonded, the flexible circuit board is welded with the insulated electrode and is positioned between the insulated electrode and the reinforcing sheet, and the reinforcing sheet is fixedly arranged on the flexible circuit board;

the side, facing the reinforcing sheet, of the non-woven fabric base layer is provided with the adhesive layer, the outline shape of the adhesive layer is the same as that of the non-woven fabric base layer, the adhesive layer is further provided with abdicating holes, and the shapes of the abdicating holes are the same as those of the reinforcing sheet;

the non-woven fabric base layer is provided with a first air hole, the adhesive layer is provided with a second air hole, and the first air hole is communicated with the second air hole;

the conductive gel is applied to the surfaces of the foam pad and the insulated electrode.

2. The electrode patch for tumor therapy according to claim 1, wherein the first vent has a cylindrical shape.

3. The electrode patch for tumor therapy according to claim 1, wherein the second vent comprises a first section adjacent to the reinforcing sheet and a second section adjacent to the nonwoven fabric base layer;

the first section is cylindrical in shape;

and/or the second section is trumpet-shaped.

4. The electrode patch for tumor therapy according to claim 1, further comprising a sweat absorbing layer made of a fiber material, wherein the sweat absorbing layer is provided with a mounting hole, and the foam pad is disposed in the mounting hole.

5. The electrode patch for tumor therapy according to claim 1, wherein the insulating electrode is made of a piezoelectric ceramic material having a dielectric constant of 5336 to 6264 at 200kHz and a dielectric loss of not more than 15%.

6. The electrode patch for tumor therapy according to claim 1, wherein the shape of the insulated electrode is circular.

7. The electrode patch for tumor therapy according to claim 1, wherein a through hole is provided at the center of the insulated electrode, and a temperature probe is provided in the through hole.

8. The electrode patch for tumor therapy according to claim 1, wherein the insulating electrode is provided with an annular silver-plated layer on a side facing the reinforcing sheet, and the thickness of the annular silver-plated layer is 0.005-0.01 mm.

9. The electrode patch for tumor therapy according to claim 1, wherein the resistance between any two points spaced apart by 10mm on the conductive gel is less than 8000 ohms.

10. The electrode patch for tumor therapy according to claim 1, wherein an acrylic double-sided tape is disposed on a side of the foam pad facing the conductive gel.

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