CN218485949U

CN218485949U - Salen Co catalyst preparation facilities

Info

Publication number: CN218485949U
Application number: CN202123053546.8U
Authority: CN
Inventors: 周怡; 胡成楠; 李�昊; 张莹
Original assignee: Fushun Shunnun Chemical Co ltd
Current assignee: Fushun Shunnun Chemical Co ltd
Priority date: 2021-12-07
Filing date: 2021-12-07
Publication date: 2023-02-17
Anticipated expiration: 2031-12-07

Abstract

The utility model discloses a Salen Co catalyst preparation device, which comprises a reaction kettle, a jacket, a dripping tank, a centrifuge and a dryer, wherein the top of the reaction kettle is fixedly connected with a motor, a stirring mechanism is rotationally connected in the reaction kettle, and the stirring mechanism is in transmission connection with an output shaft of the motor; the top of the reaction kettle is fixedly connected with a feed pipe and a tail gas pipe; the jacket is fixedly sleeved on the outer peripheral side of the reaction kettle, the side wall of the top of the jacket is fixedly connected with a jacket feeding pipe, the side wall of the bottom of the jacket is fixedly connected with a jacket discharging pipe, and the jacket feeding pipe comprises a steam pipe and a circulating water pipe which are arranged in parallel; the dripping tank is positioned above the reaction kettle, the bottom of the dripping tank is fixedly connected with a dripping pipe, and the bottom end of the dripping pipe is fixedly connected with the reaction kettle; the centrifuge is positioned below the reaction kettle, and a discharging pipe is connected between the centrifuge and the reaction kettle; the recovery tank is positioned below the centrifugal machine, and a discharge pipe is connected between the recovery tank and the centrifugal machine; the dryer is located at one side of the centrifuge and is used for recovering the solid catalyst centrifuged by the dry centrifuge.

Description

Salen Co catalyst preparation facilities

Technical Field

The utility model relates to a chemical production technical field, concretely relates to Salen Co catalyst preparation facilities.

Background

Salen is a generic name of diimines, and is one of the most important ligands in asymmetric catalytic reactions and asymmetric syntheses in recent years. Among the Salen-metal complexes, salen Co is widely used in asymmetric catalytic oxidation, cyclopropanation, hydrolysis kinetic resolution of epoxy compounds, diels-Alder reactions and other reactions due to its simple preparation method, high catalytic activity and high stereoselectivity and high enantioselectivity. The hydrolysis kinetic resolution reaction catalyzed by the Salen Co complex can provide a method for preparing chiral epoxy compounds and 1, 2-diol with high selectivity, the terminal epoxy compounds not only comprise some important synthetic building blocks, but also can be used as chiral sources to directly synthesize some drugs, and the method has the prospect of large-scale production.

The preparation route of the traditional Salen Co (II) (OAc) catalyst for preparing chiral epichlorohydrin by resolution is as follows: reacting 1,2 cyclohexanediamine serving as a starting material with L- (+) -tartaric acid to generate (R, R) - (+) -1, 2-cyclohexanediamine L-tartrate, reacting the tartrate with 3, 5-di-tert-butylsalicylaldehyde under an alkaline condition to generate (R, R) -N, N' -di (3, 5-di-tert-butylsalicylidene) -1, 2-cyclohexanediamine, and reacting the tartrate with cobalt acetate tetrahydrate to generate a chiral Salen Co (II) (OAc) catalyst. The process route has higher requirements on equipment in the process of scale-up production, and particularly has larger influence on the quality of products by the accuracy of metering and the accuracy of temperature control, so that the design of a set of device which is matched with the process requirements and is suitable for large-scale industrial production has very important significance.

Therefore, how to provide a Salen Co catalyst preparation device with simple production equipment and capable of meeting the process requirements is a problem to be solved urgently by those skilled in the art.

SUMMERY OF THE UTILITY MODEL

In view of this, the utility model provides a Salen Co catalyst preparation facilities, the device use cost is low, can accurately realize the requirement of technology production. Is suitable for large-scale industrial production.

In order to achieve the above purpose, the utility model adopts the following technical scheme: an apparatus for preparing a Salen Co catalyst, comprising:

the top of the reaction kettle is fixedly connected with a motor, a stirring mechanism is rotationally connected in the reaction kettle, and the stirring mechanism is in transmission connection with an output shaft of the motor; the top of the reaction kettle is fixedly connected with a feeding pipe and a tail gas pipe;

the jacket is fixedly sleeved on the outer peripheral side of the reaction kettle, the side wall of the top of the jacket is fixedly connected with a jacket feeding pipe, the side wall of the bottom of the jacket is fixedly connected with a jacket discharging pipe, and the jacket feeding pipe comprises a steam pipe and a circulating water pipe which are arranged in parallel;

the dripping tank is positioned above the reaction kettle, the bottom of the dripping tank is fixedly connected with a dripping pipe, and the bottom end of the dripping pipe is fixedly connected with the reaction kettle;

the centrifuge is positioned below the reaction kettle, and a discharging pipe is connected between the centrifuges;

the recovery tank is positioned below the centrifuge, and a discharge pipe is connected between the recovery tank and the centrifuge;

a dryer located at one side of the centrifuge and used for recovering the solid catalyst centrifuged by the dry centrifuge.

The beneficial effects of the utility model are that: the periphery side of reation kettle is equipped with the cover that presss from both sides, the top lateral wall fixed connection who presss from both sides the cover inlet pipe, bottom lateral wall fixed connection presss from both sides the cover discharging pipe, it includes parallelly connected steam pipe and the circulating water pipe of arranging to press from both sides the cover inlet pipe, can rationally effectual switching steam pipe and circulating water pipe toward the feed mode who presss from both sides in the cover, the temperature regulation, reaction temperature in the reation kettle is controlled through pressing from both sides the cover, improve the product quality, set up centrifuge and recovery jar in reation kettle's below, the recovery jar can be retrieved the centrifugal filtrate in the centrifuge, carry out reuse after unified processing, and the production cost is saved.

Preferably, an electronic scale is placed at the bottom of the dripping tank.

Preferably, the top edge of the reaction kettle is provided with a manhole for putting solid raw materials.

Preferably, fixedly connected with governing valve and flowmeter on the inlet pipe, the flowmeter is located and is being close to reation kettle's one side.

Preferably, the steam pipe and the circulating water pipe are both fixedly connected with regulating valves.

Preferably, the dropping pipe is fixedly connected with an adjusting valve, and the discharging pipe is fixedly connected with a switch valve.

Preferably, the stirring mechanism comprises a stirring shaft and stirring blades, the stirring blades are fixedly connected to the stirring shaft, and the stirring shaft is in transmission connection with an output shaft of the motor.

Drawings

FIG. 1 is a schematic overall view of a Salen Co catalyst preparation apparatus of the present invention.

1 reaction kettle, 2 motors, 3 jackets, 4 dropwise adding tanks, 5 centrifuges, 6 recovery tanks, 7 dryers, 8 dropwise adding pipes, 9 blanking pipes, 10 discharging pipes, 11 manholes, 12 feeding pipes, 13 tail gas pipes, 14 stirring mechanisms, 1401 stirring shafts, 1402 stirring blades, 15 flowmeters, 16 steam pipes, 17 circulating water pipes, 18 jacket discharging pipes, 19 regulating valves, 20 electronic scales and 21 switch valves.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts all belong to the protection scope of the present invention.

Referring to the utility model discloses attached figure 1, according to the utility model discloses a Salen Co catalyst preparation facilities, it includes:

the device comprises a reaction kettle 1, wherein the top of the reaction kettle 1 is fixedly connected with a motor 2, a stirring mechanism 14 is rotationally connected in the reaction kettle 1, and the stirring mechanism 14 is in transmission connection with an output shaft of the motor; the top of the reaction kettle 1 is fixedly connected with a feed pipe 12 and a tail gas pipe 13; the stirring mechanism stirs the materials in the reaction kettle to be uniformly mixed.

The reaction kettle comprises a jacket 3, wherein the jacket 3 is fixedly sleeved on the outer peripheral side of the reaction kettle 1, the side wall of the top of the jacket 3 is fixedly connected with a jacket feed pipe, the side wall of the bottom of the jacket 3 is fixedly connected with a jacket discharge pipe 18, and the jacket feed pipe comprises a steam pipe 16 and a circulating water pipe 17 which are arranged in parallel; the jacket is sleeved on the outer side wall of the reaction kettle, the reaction temperature in the reaction kettle is adjusted by the steam or water in the jacket,

specifically, the thermometer is arranged in the jacket, so that the temperature in the jacket can be known conveniently.

The dripping tank 4 is positioned above the reaction kettle 1, the bottom of the dripping tank 4 is fixedly connected with a dripping pipe 8, and the bottom end of the dripping pipe 8 is fixedly connected with the reaction kettle 1; the dropwise add jar passes through the dropwise add pipe and realizes being connected with reation kettle, provides the material for reation kettle's reaction.

The centrifugal machine 5 is positioned below the reaction kettle 1, and a discharge pipe 9 is connected between the centrifugal machine 5 and the reaction kettle 1;

the recovery tank 6 is positioned below the centrifugal machine 5, and a discharge pipe 10 is connected between the recovery tank 6 and the centrifugal machine 5; the recovery tank is used for recovering centrifugal filtrate through a discharge pipe; the reuse of the filtrate is realized, and the production cost is saved.

A drier 7, the drier 7 is positioned at one side of the centrifuge 5 and is used for recovering the solid catalyst centrifuged by the dry centrifuge.

In some embodiments, an electronic scale 20 is placed at the bottom of drip tank 4. The device is used for accurately metering and weighing the dripped materials; the reaction conditions are precisely controlled. And a better reaction effect is realized.

In other embodiments, the top edge of the reaction kettle 1 is provided with a manhole 11 for putting solid raw materials.

In other embodiments, the feed pipe 12 is fixedly connected with a regulating valve 19 and a flow meter 15, and the flow meter 15 is positioned at one side close to the reaction kettle 1. The feeding amount can be accurately obtained.

In other embodiments, the steam pipe 16 and the circulating water pipe 17 are both fixedly connected with regulating valves 19. For controlling the flow rate. The two can be switched according to actual needs to control the reaction temperature.

In other embodiments, the dropping pipe 8 is fixedly connected with a regulating valve 19, and the blanking pipe 9 is fixedly connected with a switch valve 21.

Specifically, the stirring mechanism 14 comprises a stirring shaft 1401 and stirring blades 1402, the stirring blades 1402 are fixedly connected to the stirring shaft 1401, and the stirring shaft 1401 is in transmission connection with an output shaft of the motor 2.

The utility model discloses a Salen Co catalyst preparation device, which can switch the heating mode according to the actual need by the steam pipe 16 and the circulating water pipe 17 which are arranged in parallel by the jacket feeding pipe, and can achieve the effect of temperature control; the centrifugal filter liquor can be effectively recycled by the aid of the recycling tank 6, so that the solvent can be recycled, and finished products can be saved.

For the device and the using method disclosed by the embodiment, the description is simple because the device and the using method correspond to the method disclosed by the embodiment, and the relevant points can be referred to the description of the method part.

The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. An apparatus for producing a Salen Co catalyst, comprising:

the device comprises a reaction kettle (1), wherein the top of the reaction kettle (1) is fixedly connected with a motor (2), a stirring mechanism (14) is rotationally connected in the reaction kettle (1), and the stirring mechanism (14) is in transmission connection with an output shaft of the motor; the top of the reaction kettle (1) is fixedly connected with a feeding pipe (12) and a tail gas pipe (13);

the reaction kettle comprises a jacket (3), wherein the jacket (3) is fixedly sleeved on the outer peripheral side of the reaction kettle (1), the side wall of the top of the jacket (3) is fixedly connected with a jacket feeding pipe, the side wall of the bottom of the jacket (3) is fixedly connected with a jacket discharging pipe (18), and the jacket feeding pipe comprises a steam pipe (16) and a circulating water pipe (17) which are arranged in parallel;

the device comprises a dropwise adding tank (4), wherein the dropwise adding tank (4) is positioned above the reaction kettle (1), the bottom of the dropwise adding tank (4) is fixedly connected with a dropwise adding pipe (8), and the bottom end of the dropwise adding pipe (8) is fixedly connected with the reaction kettle (1);

the centrifugal machine (5) is positioned below the reaction kettle (1), and a discharging pipe (9) is connected between the centrifugal machine (5) and the reaction kettle (1);

the recovery tank (6) is positioned below the centrifuge (5), and a discharge pipe (10) is connected between the recovery tank (6) and the centrifuge;

a dryer (7), said dryer (7) being located on one side of said centrifuge (5) and being adapted to recover solid catalyst centrifuged by a dry centrifuge.

2. The Salen Co catalyst production apparatus of claim 1, wherein an electronic scale (20) is placed on the bottom of said addition tank (4).

3. The Salen Co catalyst preparation device according to claim 1, wherein a manhole (11) for putting solid raw materials is opened at the top edge of the reaction kettle (1).

4. The Salen Co catalyst production apparatus according to claim 1, wherein said feed pipe (12) is fixedly connected with a control valve (19) and a flow meter (15), and said flow meter (15) is located at a side close to said reaction vessel (1).

5. The Salen Co catalyst production apparatus according to claim 1, wherein said steam pipe (16) and said circulating water pipe (17) are each fixedly connected with a control valve (19).

6. The Salen Co catalyst preparation device according to claim 1, wherein said dropping pipe (8) is fixedly connected with a regulating valve (19), and said discharging pipe (9) is fixedly connected with a switch valve (21).

7. The Salen Co catalyst preparation device according to claim 1, wherein said stirring mechanism (14) comprises a stirring shaft (1401) and stirring blades (1402), said stirring blades (1402) are fixedly connected to said stirring shaft (1401), and said stirring shaft (1401) is in transmission connection with an output shaft of said motor (2).