CN218483647U - Hemopoietic stem cell precooling apparatus - Google Patents

Hemopoietic stem cell precooling apparatus Download PDF

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Publication number
CN218483647U
CN218483647U CN202222485729.5U CN202222485729U CN218483647U CN 218483647 U CN218483647 U CN 218483647U CN 202222485729 U CN202222485729 U CN 202222485729U CN 218483647 U CN218483647 U CN 218483647U
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Prior art keywords
water bath
lid
box
bag
rope
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CN202222485729.5U
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雒猛
胡淑琪
周云霄
刘庆凯
吕玲
张秀涛
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Shandong Qilu Stem Cell Engineering Co ltd
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Shandong Qilu Stem Cell Engineering Co ltd
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Abstract

The utility model belongs to the technical field of the medical instrument technique and specifically relates to just a hemopoietic stem cell precooling apparatus, including water bath box, a plurality of water bath box and a plurality of water bath bag, the removable lid link that is connected with that washes in water bath box top, a plurality of connector and hanging hole have evenly been seted up on the lid link, and detachable is connected with the case lid on the connector, the case lid downside is equipped with the gag lever post, and the water bath box includes lid and box body, the water bath bag sets up in the box body, the opening and the lid integrated into one piece of water bath bag, be connected with two hanging rods on the water bath box, the hanging hole is used for holding the hanging rod. Set up the lid link on the water bath case, set up the water bath box of built-in water bath bag, place the water bath box in the water bath case, with box body and lid separation during the use, can satisfy the rapid cooling demand to the inside blood sample of water bath bag, also can prevent simultaneously that the blood bag from soaking in the water bath, can effectively reduce the pollution risk of blood bag, convenient to use, the precooling is efficient.

Description

Hemopoietic stem cell precooling apparatus
Technical Field
The utility model belongs to the technical field of medical instrument technique and specifically relates to just a hemopoietic stem cell precooling apparatus.
Background
Dimethyl sulfoxide is a commonly used cryopreservation protective agent in the process of cell cryopreservation, but the dimethyl sulfoxide has high cytotoxicity at normal temperature, so that cells needing cryopreservation are usually pre-cooled to 4 ℃, and then the cryopreservation protective agent is added into the cells.
The precooling method in the prior art mainly adopts two modes of wind cooling and water cooling. The problems of the air-cooled precooling device are as follows: the radiation conduction efficiency is slow and easy to exchange violently with the ambient temperature, the set cold air temperature is too high, the precooling time can be too long, the working efficiency is influenced, the set cold air temperature is too low, and the risk of freezing the hematopoietic stem cells exists. The water cooling device has the advantages of high cooling speed and small temperature exchange influence with the ambient temperature. However, the existing water cooling equipment is easy to wet blood bag labels and pollute samples when in use.
SUMMERY OF THE UTILITY MODEL
For the problem that wets the blood bag label easily when solving above-mentioned water cooling equipment and result in the sample pollution even, the utility model provides a hemopoietic stem cell precooling apparatus.
The utility model provides a technical scheme that its technical problem adopted is: the utility model provides a hemopoietic stem cell precooling apparatus, includes water bath box, a plurality of water bath box and a plurality of water bath bag, the removable abluent lid link that is connected with in water bath box top, evenly seted up a plurality of connector and hanging hole on the lid link, detachable is connected with the case lid on the connector, the case lid downside is equipped with the gag lever post, and the water bath box includes lid and box body, the water bath bag sets up in the box body, the opening and the lid integrated into one piece of water bath bag, be connected with two hanging rods on the water bath box, the hanging hole is used for holding the hanging rod.
As optimization, the downside of water bath be connected with the landing leg, the inside storage water tank that is equipped with of water bath, the inboard bottom slope setting of storage water tank, the lower one end in the inboard bottom of storage water tank is connected with the drain pipe, the inside temperature sensor that is equipped with of storage water tank is equipped with compressor and controller between water bath and the storage water tank, and water bath outside is equipped with display screen and control button, display screen, control button and temperature sensor all link to each other with the controller, the controller is used for carrying out the order to the compressor.
Preferably, the opening area of the connecting port is larger than the cross-sectional area of the water bath box, the connecting port penetrates through the cover body connecting frame, the hanging hole is cylindrical, and the hanging hole is adjacent to the connecting port.
As optimization, waist a week of water bath bag be equipped with the rope bag, the rope bag is inside to be equipped with the rope that contracts of pine, the both ends that the rope that contracts of pine upwards pass the lid and set up in the lid upside, the both ends that the rope that contracts of pine all are equipped with the fag end, the rope that contracts of pine and lid sliding connection, the lid upside is equipped with hangs the rope pole, hangs the rope pole and contracts the rope with the pine and the adjacent setting in junction of lid.
As optimization, water bath tank top a week be equipped with heavy groove, the downside a week of lid link is equipped with the sealing strip, heavy groove is used for holding the sealing strip, lid link upside is equipped with the pull ring.
As optimization, the lid on be connected with the slide bar, slide bar upper portion links firmly with the lid, and the slide bar lower extreme sets up in the box body inside downwards, the slide bar lower extreme is equipped with the spacing collar, the inside cavity that is of slide bar, slide bar internal connection have a locking lever, and the locking lever upper end is connected with the regulation handle, and the regulation handle is located the upside of slide bar, locking lever length is greater than the length of slide bar, the locking lever lower extreme is equipped with the threaded connection section, the peg links firmly with the slide bar that is located the lid upside.
As an optimization, the box body inside be equipped with the connecting pore, the vertical setting of connecting pore, the bottom of connecting pore is equipped with threaded connection hole downwards, threaded connection hole and threaded connection section cooperation are connected, the upper end aperture of connecting pore is less than the aperture of connecting pore, the slide bar lower part sets up in connecting pore, the diameter of connecting pore is greater than the external diameter of spacing collar, the upper end aperture of connecting pore is less than the external diameter of spacing collar.
The beneficial effect of this scheme is: a hematopoietic stem cell precooling apparatus, having the following benefits:
set up the lid link on the water bath, set up the water bath box of built-in water bath bag, place the water bath box in the water bath box, during the use with box body and lid separation, can satisfy the rapid cooling demand to the inside blood sample of water bath bag, also can prevent that the blood bag from soaking in the water bath, can effectively reduce the pollution risk of blood bag, satisfy simultaneously at freezing protectant infusion, the heat seal in-process, the blood sample is in cold water bath all the time, effectively keep the temperature, reduce the toxicity damage of freezing protectant to the cell, high durability and convenient use, the precooling efficiency is high.
Drawings
Fig. 1 is a schematic axial view of the present invention.
Figure 2 is the axle side schematic view of the utility model discloses case lid.
Fig. 3 is a schematic axial view of the present invention without a case cover.
Fig. 4 is a schematic view of the bottom of the cover connecting frame on the shaft side.
Fig. 5 is a schematic side view of the water bath box of the present invention.
Figure 6 is a schematic axial view of the water bath box of the utility model.
Fig. 7 is a schematic front view of the water bath box of the present invention.
Fig. 8 isbase:Sub>A schematic view ofbase:Sub>A-base:Sub>A cutting structure of fig. 7 of the present invention.
Fig. 9 is a schematic axial view of the water bath bag of the present invention.
The water bath box comprises a water bath box body 1, a water bath box body 2, a water bath box body 3, a water bath bag 4, a cover body connecting frame 5, a connecting port 6, a hanging hole 7, a box cover 8, a box cover 9, a box body 10, a hanging rod 11, a limiting rod 12, a supporting leg 13, a drain pipe 14, a display screen 15, a rope bag 16, a loosening and contracting rope 17, a rope cap 18, a rope hanging rod 19, a sinking groove 20, a sealing strip 21, a pull ring 22, a sliding rod 23, a limiting ring 24, a locking rod 25 and a connecting pore channel.
Detailed Description
To make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the attached drawings in the embodiments of the present invention are combined to clearly and completely describe the technical solution in the embodiments of the present invention, and obviously, the described embodiments are part of the embodiments of the present invention, rather than all embodiments. The components of embodiments of the present invention, as generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts all belong to the protection scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate the position or positional relationship based on the position or positional relationship shown in the drawings, or the position or positional relationship which is usually placed when the product of the present invention is used, and are only for convenience of description and simplification of the description, but do not indicate or imply that the device or element referred to must have a specific position, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another, and are not to be construed as indicating or implying relative importance.
As shown in fig. 1, 2 and 6, a hematopoietic stem cell precooling apparatus, including water bath 1, a plurality of water bath box 2 and a plurality of water bath bag 3, removable the washing be connected with lid link 4 in water bath 1 top, evenly seted up a plurality of connector 5 and hanging hole 6 on the lid link 4, detachable is connected with case lid 7 on the connector 5, 7 downside of case lid is equipped with gag lever post 11, and water bath box 2 includes lid 8 and box body 9, water bath bag 3 sets up in box body 9, and the opening and the 8 integrated into one piece of lid of water bath bag 3, be connected with two peg 10 on the water bath box 2, hanging hole 6 is used for holding peg 10 and gag lever post 11.
As shown in fig. 1, the downside of water bath 1 be connected with landing leg 12, water bath 1 is inside to be equipped with the storage water tank, the inboard bottom slope setting of storage water tank, the lower one end in the inboard bottom of storage water tank is connected with drain pipe 13, the inside temperature sensor that is equipped with of storage water tank, be equipped with compressor and controller between water bath 1 and the storage water tank, water bath 1 outside is equipped with display screen 14 and control button, display screen 14, control button and temperature sensor all link to each other with the controller, the controller is used for carrying out the order to the compressor.
As shown in fig. 1, the opening area of the connection port 5 is larger than the cross-sectional area of the water bath box 2, the connection port 5 is disposed through the cover connection frame 4, the hanging hole 6 is cylindrical, and the hanging hole 6 is disposed adjacent to the connection port 5.
As shown in fig. 6 and 9, a rope bag 15 is arranged around the waist of the water bath bag 3, a flexible rope 16 is arranged inside the rope bag 15, two ends of the flexible rope 16 upwards penetrate through the box cover 8 and are arranged on the upper side of the box cover 8, two ends of the flexible rope 16 are respectively provided with a rope cap 17, the flexible rope 16 is slidably connected with the box cover 8, a rope hanging rod 18 is arranged on the upper side of the box cover 8, and the rope hanging rod 18 is arranged adjacent to the joint of the flexible rope 16 and the box cover 8.
As shown in fig. 4 and 5, a peripheral of the top of the water bath tank 1 is provided with a sinking groove 19, a peripheral of the lower side of the cover body connecting frame 4 is provided with a sealing strip 20, the sinking groove 19 is used for accommodating the sealing strip 20, and the upper side of the cover body connecting frame 4 is provided with a pull ring 21.
As shown in fig. 6 and 8, the box cover 8 is connected with a sliding rod 22, the upper part of the sliding rod 22 is fixedly connected with the box cover 8, the lower end of the sliding rod 22 is downwards arranged inside the box body 9, the lower end of the sliding rod 22 is provided with a limiting ring 23, the sliding rod 22 is hollow, the sliding rod 22 is internally connected with a locking rod 24, the upper end of the locking rod 24 is connected with a regulating handle, the regulating handle is positioned at the upper side of the sliding rod 22, the length of the locking rod 24 is greater than that of the sliding rod 22, the lower end of the locking rod 24 is provided with a threaded connection section, and the hanging rod 10 is fixedly connected with the sliding rod 22 positioned at the upper side of the box cover 8.
As shown in fig. 7 and 8, a connecting hole 25 is arranged inside the box body 9, the connecting hole 25 is vertically arranged, a threaded connecting hole is arranged at the bottom of the connecting hole 25 downwards, the threaded connecting hole is connected with the threaded connecting section in a matching manner, the upper end aperture of the connecting hole 25 is smaller than the aperture of the connecting hole 25, the lower part of the sliding rod 22 is arranged in the connecting hole 25, the diameter of the connecting hole 25 is larger than the outer diameter of the limiting ring 23, and the upper end aperture of the connecting hole 25 is smaller than the outer diameter of the limiting ring 23.
When the device is used specifically, water is injected into the water bath tank, the liquid level is positioned at the lower side of the cover body connecting frame 4, the device is opened 30min in advance, the temperature to be precooled is set through the control button, the controller controls the compressor to work, and the water in the water bath tank 1 is precooled;
putting the blood bag filled with the cord blood into the water bath bag 3 through the opening of the water bath bag 3, pulling the rope cap 17, and tightening the loosening and shrinking rope 16 to wrap the water bath bag 3 outside the blood bag;
taking down one of the box covers 7, putting the water bath box 2 into the connecting port 5 from top to bottom, and hanging the hanging rod 10 into the hanging hole 6;
the adjusting handle is rotated to enable the threaded connection section of the locking rod 24 to be disengaged from the threaded connection hole, the box body 9 slides downwards along the sliding rod 22 to the limiting ring 23, the box cover 8 is separated from the box body 9, the water bath bag 3 is exposed in cold water for precooling, the temperature sensor adopts an infrared temperature sensor to detect the heat of the water bath bag 3, and the detection result is displayed through the display screen 14 until the temperature of the water bath bag 3 reaches the precooling temperature;
the water bath box 2 is lifted upwards by holding the hanging rod 10, the sliding rod 22 is inserted into the connecting pore channel 25, the handle is rotated, the threaded connecting section of the locking rod 24 is screwed into the threaded connecting hole by adjusting the handle, the cover body and the box body are reconnected, the blood bag and the water bath bag 3 are always positioned in cold water, and then the infusion work of the cryoprotectant can be carried out;
after the infusion of the cryoprotectant is finished, the loosening and shrinking rope 16 is loosened, the blood bag is taken out, and the water bath box 2 is put into the water bath box 1 again.
The position of the controller is set by the worker according to the actual condition during operation, and the controller is used for controlling used electric appliances in the scheme and comprises but is not limited to a sensor, a motor, a telescopic rod, a water pump, a solenoid valve, a heating wire, a heat pump, a display screen, computer input equipment, a switch button, communication equipment, a lamp, a loudspeaker and a microphone; the controller is an Intel processor, an AMD processor, a PLC controller, an ARM processor or a single chip microcomputer, and also comprises a mainboard, a memory bank, a storage medium and a power supply source, wherein the power supply source is a commercial power or a lithium battery; when the display screen is provided, the display card is also provided; for the operation principle of the controller, please refer to "automatic control principle", microcontroller principle and application simulation case "and" sensor principle and application "published by Qinghua university Press, and other books in the field can be read by reference; other non-mentioned automation control and consumer devices are well known to those skilled in the art and will not be described herein.
The above embodiments are only specific cases of the present invention, and the protection scope of the present invention includes but is not limited to the product form and style of the above embodiments, any suitable changes or modifications made by a person of ordinary skill in the art and a hematopoietic stem cell precooling apparatus according to the claims of the present invention shall fall within the protection scope of the present invention.

Claims (7)

1. A hematopoietic stem cell precooling apparatus, characterized in that: including water bath box, a plurality of water bath box and a plurality of water bath bag, the removable abluent lid link that is connected with in water bath box top, evenly seted up a plurality of connector and hanging hole on the lid link, detachable is connected with the case lid on the connector, the case lid downside is equipped with the gag lever post, and water bath box includes lid and box body, the water bath bag sets up in the box body, the opening and the lid integrated into one piece of water bath bag, be connected with two pegs on the water bath box, the hanging hole is used for holding the peg.
2. A hematopoietic stem cell precooling apparatus according to claim 1, wherein: the downside of water bath be connected with the landing leg, the inside storage water tank that is equipped with of water bath, the inboard bottom slope setting of storage water tank, the lower one end in the inboard bottom of storage water tank is connected with the drain pipe, the inside temperature sensor that is equipped with of storage water tank is equipped with compressor and controller between water bath and the storage water tank, water bath outside is equipped with display screen and control button, display screen, control button and temperature sensor all link to each other with the controller, the controller is used for carrying out the order to the compressor.
3. A hematopoietic stem cell precooling apparatus according to claim 2, wherein: the opening area of the connecting port is larger than the cross-sectional area of the water bath box, the connecting port penetrates through the cover body connecting frame, the hanging hole is cylindrical, and the hanging hole is adjacent to the connecting port.
4. A hematopoietic stem cell precooling apparatus according to claim 3, wherein: waist a week of water bath bag be equipped with the rope sling, the rope sling is inside to be equipped with the pine rope that contracts, the both ends that the rope that contracts of pine upwards pass the lid and set up in the lid upside, the both ends that the rope that contracts of pine all are equipped with the fag end, the rope that contracts of pine and lid sliding connection, the lid upside is equipped with hangs the rope pole, hangs the rope pole and the pine contracts the rope and the adjacent setting of junction of lid.
5. The hematopoietic stem cell precooling apparatus of claim 4, wherein: the water bath tank top a week be equipped with heavy groove, the downside a week of lid link is equipped with the sealing strip, heavy groove is used for holding the sealing strip, lid link upside is equipped with the pull ring.
6. A hematopoietic stem cell precooling apparatus according to claim 5, wherein: the box cover on be connected with the slide bar, slide bar upper portion and lid link firmly, the slide bar lower extreme sets up in the box body inside downwards, the slide bar lower extreme is equipped with the spacing collar, the inside cavity that is of slide bar, slide bar internal connection have a locking lever, the locking lever upper end is connected with the regulation handle, and the regulation handle is located the upside of slide bar, locking lever length is greater than the length of slide bar, the locking lever lower extreme is equipped with the threaded connection section, the peg links firmly with the slide bar that is located the lid upside.
7. The hematopoietic stem cell precooling apparatus according to claim 6, wherein: the box body inside be equipped with the connecting hole, the vertical setting of connecting hole, the bottom of connecting hole is equipped with threaded connection hole downwards, threaded connection hole is connected with the threaded connection section cooperation, the upper end aperture of connecting hole is less than the aperture of connecting hole, the slide bar lower part sets up in connecting hole, the diameter of connecting hole is greater than the external diameter of spacing collar, the upper end aperture of connecting hole is less than the external diameter of spacing collar.
CN202222485729.5U 2022-09-20 2022-09-20 Hemopoietic stem cell precooling apparatus Active CN218483647U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222485729.5U CN218483647U (en) 2022-09-20 2022-09-20 Hemopoietic stem cell precooling apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222485729.5U CN218483647U (en) 2022-09-20 2022-09-20 Hemopoietic stem cell precooling apparatus

Publications (1)

Publication Number Publication Date
CN218483647U true CN218483647U (en) 2023-02-17

Family

ID=85191285

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202222485729.5U Active CN218483647U (en) 2022-09-20 2022-09-20 Hemopoietic stem cell precooling apparatus

Country Status (1)

Country Link
CN (1) CN218483647U (en)

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