CN218454176U - Improved nucleic acid adsorption column - Google Patents

Improved nucleic acid adsorption column Download PDF

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Publication number
CN218454176U
CN218454176U CN202222893739.2U CN202222893739U CN218454176U CN 218454176 U CN218454176 U CN 218454176U CN 202222893739 U CN202222893739 U CN 202222893739U CN 218454176 U CN218454176 U CN 218454176U
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China
Prior art keywords
connecting block
nucleic acid
outer sleeve
adsorption column
main pipe
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CN202222893739.2U
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Chinese (zh)
Inventor
安方玉
孙柏
颜春鲁
汪春梅
刘仕卿
夏楉榴
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Gansu University of Chinese Medicine
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Gansu University of Chinese Medicine
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Priority to CN202222893739.2U priority Critical patent/CN218454176U/en
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Abstract

The utility model belongs to the technical field of molecular biology, especially, do: an improved nucleic acid adsorption column comprises an outer sleeve, wherein an elastic pad is arranged on the outer side of the outer sleeve, a main pipe is arranged inside the outer sleeve, a connecting block is arranged at the upper end of the outer sleeve, a fixing frame is arranged on the outer side of the main pipe, finger sleeves are arranged on two sides of the upper end of the fixing frame, soft pads are arranged on the inner sides of the finger sleeves, a plug is arranged at the upper end of the main pipe, and the connecting block is pushed to be attached to a sealing pad, so that the sealing pad pushes a push rod to extrude an elastic sheet, and the connecting block is tightly attached to the sealing pad; the sealing gasket is matched with the connecting block in a V-shaped manner, so that the sealing gasket and the connecting block are mutually matched, the gap at the joint of the outer sleeve and the main pipe is reduced, and the liquid in the outer sleeve is prevented from leaking; through the setting of elastic pad, avoid outer sleeve pipe and device to produce the collision in the process of carrying out nucleic acid separation and extracting, and then avoid it to produce and break.

Description

Improved nucleic acid adsorption column
Technical Field
The utility model belongs to the technical field of molecular biology, concretely relates to modified nucleic acid adsorption column.
Background
Nucleic acid refers to a biological macromolecular compound formed by polymerizing a plurality of nucleotides, and is one of the most basic substances of life, and nucleic acid extraction is a basic method of molecular biology, is the first step of all molecular biology experiments, and is the starting point of downstream nucleic acid detection, diagnostic analysis or product development. The quality and integrity of the extracted nucleic acids directly affects the study or diagnostic results. Therefore, nucleic acid extraction is one of the most critical operation steps in molecular biology.
The original improved nucleic acid adsorption column has the following defects in use:
1. the original improved nucleic acid adsorption column has the advantages that the connection between the main pipe and the outer sleeve is in a sleeved connection in use, and when the nucleic acid adsorption column falls down, liquid in the outer sleeve is easy to leak out from a gap, so that pollution is caused.
2. The original improved nucleic acid adsorption column has the defects that the outer wall is smooth when in use, and the original improved nucleic acid adsorption column is easy to drop because an experimenter does not stably hold the column in the taking process, so that the column is broken to cause pollution.
SUMMERY OF THE UTILITY MODEL
For solving the above-mentioned problem that exists among the prior art, the utility model provides a modified nucleic acid adsorption column has the characteristics of being convenient for take, and is sealed effectual, easy operation.
In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a modified nucleic acid adsorption column, includes the outer tube, the outside of outer tube is equipped with the cushion, the inside of outer tube is equipped with the person in charge, the upper end of outer tube is equipped with the connecting block, the outside of being responsible for is equipped with the mount, the upper end both sides of mount all are equipped with the dactylotheca, the inboard of dactylotheca all is equipped with the cushion, the upper end of being responsible for is equipped with the stopper, the liquid outlet has been seted up to the lower extreme of being responsible for, the inside lower extreme of being responsible for is equipped with the separation membrane, movable groove has been seted up to the inside lower extreme of mount, the inside upper end in movable groove is equipped with the flexure strip, the lower extreme of flexure strip is equipped with the push rod, the lower extreme of push rod is equipped with sealed the pad.
As the utility model discloses a preferred technical scheme of modified nucleic acid adsorption column, the cushion is connected with the outer tube through the registration, the stopper is connected with the outer tube through the screw thread, the separation membrane is fixed connection with being responsible for, the dactylotheca is fixed connection with being responsible for, the mount is fixed connection with being responsible for.
As the utility model discloses a preferred technical scheme of modified nucleic acid adsorption column, the connecting block is fixed connection with the outer tube, the connecting block is connected for the laminating with sealed the pad, the dactylotheca is connected with the cushion through the registration, sealed pad is fixed connection with the push rod.
As the utility model discloses a preferred technical scheme of modified nucleic acid adsorption column, the connecting block is connected with the mount through the screw thread, the push rod is connected with the mount through the block, sealed pad is connected with the mount through the push rod.
As the utility model discloses a preferred technical scheme of modified nucleic acid adsorption column, the connecting block is connected with the person in charge through the mount, the outer tube is connected with the mount through the connecting block.
As the utility model discloses a preferred technical scheme of modified nucleic acid adsorption column, the push rod is connected with the person in charge through the mount.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the connecting block is pushed to be attached to the sealing gasket, so that the sealing gasket pushes the push rod, the push rod extrudes the elastic sheet, and the connecting block is tightly attached to the sealing gasket; the sealing gasket is matched with the connecting block in a V-shaped manner, so that the sealing gasket and the connecting block are mutually matched, the gap at the joint of the outer sleeve and the main pipe is reduced, and the liquid in the outer sleeve is prevented from leaking; through the setting of elastic pad, avoid outer sleeve pipe and device to produce the collision in the in-process that carries out nucleic acid separation and draws, and then avoid it to produce and break.
2. Through the setting of dactylotheca, can make the experimenter insert the inside of dactylotheca with pointing when using to avoid not taking the outer tube to cause the test tube to drop because of the experimenter, avoid then that the outer tube drops and make inside liquid seepage, cause the pollution.
Drawings
The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention. In the drawings:
fig. 1 is a schematic three-dimensional structure of the present invention;
FIG. 2 is a schematic view of the present invention in partial section;
FIG. 3 is a schematic view of a partial cross-sectional structure of the middle main pipe of the present invention;
FIG. 4 is a schematic view of a partially enlarged structure at A of the present invention;
in the figure: 1. an outer sleeve; 2. a main tube; 3. an elastic pad; 4. a fixed mount; 5. finger stall; 6. a soft cushion; 7. a plug; 8. separating the membrane; 9. connecting blocks; 10. a liquid outlet; 11. a gasket; 12. a push rod; 13. an elastic sheet; 14. a movable groove.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Examples
Referring to fig. 1-4, the present invention provides the following technical solutions: the utility model provides a modified nucleic acid adsorption column, including outer tube 1, the outside of outer tube 1 is equipped with cushion 3, the inside of outer tube 1 is equipped with and is responsible for 2, the upper end of outer tube 1 is equipped with connecting block 9, the outside of being responsible for 2 is equipped with mount 4, the upper end both sides of mount 4 all are equipped with dactylotheca 5, the inboard of dactylotheca 5 all is equipped with cushion 6, the upper end of being responsible for on 2 is equipped with stopper 7, liquid outlet 10 has been seted up to the lower extreme of being responsible for 2, the inside lower extreme of being responsible for 2 is equipped with separating membrane 8, movable groove 14 has been seted up to the inside lower extreme of mount 4, the inside upper end of movable groove 14 is equipped with flexure strip 13, the lower extreme of flexure strip 13 is equipped with push rod 12, the lower extreme of push rod 12 is equipped with sealed pad 11.
Specifically, the elastic pad 3 is connected with the outer sleeve 1 by a sleeve, the plug 7 is connected with the outer sleeve 1 by a thread, the separation membrane 8 is fixedly connected with the main pipe 2, the finger stall 5 is fixedly connected with the main pipe 2, the fixing frame 4 is an L-shaped annular member in the embodiment, and a thread is arranged on one side of the fixing frame 4.
Specifically, connecting block 9 is fixed connection with outer tube 1, and connecting block 9 is connected for the laminating with sealed pad 11, and dactylotheca 5 is connected with cushion 6 through the registration, and sealed pad 11 is fixed connection with push rod 12, and sealed pad 11 is the cooperation component of V-arrangement with connecting block 9 in this embodiment, and one side of connecting block 9 is equipped with the screw thread with mount 4 matched with.
Specifically, the connecting block 9 is connected to the fixing frame 4 through a thread, the push rod 12 is connected to the fixing frame 4 through a snap fit, and the sealing gasket 11 is connected to the fixing frame 4 through the push rod 12, where the push rod 12 is a T-shaped annular member in this embodiment.
Specifically, the connecting block 9 is connected with the main pipe 2 through the fixing frame 4, and the outer sleeve 1 is connected with the fixing frame 4 through the connecting block 9.
Specifically, the push rod 12 is connected to the main pipe 2 through the fixing frame 4.
The utility model discloses a theory of operation and use flow: rotating the outer sleeve 1, screwing the connecting block 9 at the upper end of the outer sleeve 1 into the fixed frame 4, enabling the connecting block 9 to be attached to the sealing gasket 11 at the lower end in the fixed frame 4, enabling the sealing gasket 11 to push the push rod 12 at one end of the sealing gasket, enabling the push rod 12 to extrude the elastic sheet 13 in the movable groove 14, and after reaching a certain position, resetting the elastic sheet 13 to push the sealing gasket 11 to be attached to the connecting block 9, so that the sealing effect of the sealing gasket is enhanced; the device is placed in a centrifuge, and when the device collides with the device, the device is effectively buffered by an elastic pad 3 positioned on the outer side of an outer sleeve 1; when the outer tube 1 is taken out from the centrifuge, a finger is inserted into the inside of the finger cot 5 to clamp the main tube 2, thereby preventing it from falling.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described above, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (6)

1. An improved nucleic acid adsorption column, characterized in that: including outer tube (1), the outside of outer tube (1) is equipped with cushion (3), the inside of outer tube (1) is equipped with and is responsible for (2), the upper end of outer tube (1) is equipped with connecting block (9), the outside of being responsible for (2) is equipped with mount (4), the upper end both sides of mount (4) all are equipped with dactylotheca (5), the inboard of dactylotheca (5) all is equipped with cushion (6), the upper end on being responsible for (2) is equipped with stopper (7), liquid outlet (10) have been seted up to the lower extreme of being responsible for (2), the inside lower extreme of being responsible for (2) is equipped with separating membrane (8), movable groove (14) have been seted up to the inside lower extreme of mount (4), the inside upper end of movable groove (14) is equipped with flexure strip (13), the lower extreme of flexure strip (13) is equipped with push rod (12), the lower extreme of push rod (12) is equipped with sealed pad (11).
2. The improved nucleic acid adsorption column of claim 1, wherein: the elastic cushion (3) is connected with the outer sleeve (1) through sleeving, the plug (7) is connected with the outer sleeve (1) through threads, the separation membrane (8) is fixedly connected with the main pipe (2), the finger stall (5) is fixedly connected with the main pipe (2), and the fixing frame (4) is fixedly connected with the main pipe (2).
3. The improved nucleic acid adsorption column of claim 1, wherein: connecting block (9) are fixed connection with outer tube (1), connecting block (9) are connected for the laminating with sealed pad (11), dactylotheca (5) are connected with cushion (6) through the registrate, sealed pad (11) are fixed connection with push rod (12).
4. The improved nucleic acid adsorption column of claim 1, wherein: the connecting block (9) is connected with the fixing frame (4) through threads, the push rod (12) is connected with the fixing frame (4) through clamping, and the sealing gasket (11) is connected with the fixing frame (4) through the push rod (12).
5. The improved nucleic acid adsorption column of claim 1, wherein: the connecting block (9) is connected with the main pipe (2) through the fixing frame (4), and the outer sleeve (1) is connected with the fixing frame (4) through the connecting block (9).
6. The improved nucleic acid adsorption column of claim 1, wherein: the push rod (12) is connected with the main pipe (2) through the fixing frame (4).
CN202222893739.2U 2022-11-01 2022-11-01 Improved nucleic acid adsorption column Active CN218454176U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222893739.2U CN218454176U (en) 2022-11-01 2022-11-01 Improved nucleic acid adsorption column

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222893739.2U CN218454176U (en) 2022-11-01 2022-11-01 Improved nucleic acid adsorption column

Publications (1)

Publication Number Publication Date
CN218454176U true CN218454176U (en) 2023-02-07

Family

ID=85126633

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202222893739.2U Active CN218454176U (en) 2022-11-01 2022-11-01 Improved nucleic acid adsorption column

Country Status (1)

Country Link
CN (1) CN218454176U (en)

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