CN218445154U - Urine galactose self-testing device and system - Google Patents
Urine galactose self-testing device and system Download PDFInfo
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- CN218445154U CN218445154U CN202222599195.9U CN202222599195U CN218445154U CN 218445154 U CN218445154 U CN 218445154U CN 202222599195 U CN202222599195 U CN 202222599195U CN 218445154 U CN218445154 U CN 218445154U
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Abstract
The utility model provides a urine galactose self-test device, include: the device comprises a shell, wherein a sample inlet and an observation port are respectively arranged at two ends of one side of the shell; the detection mechanism is arranged in the cavity of the shell and is fixedly connected with the shell, the detection mechanism comprises a liquid storage cabin, a filtering cabin and a detection cabin, the liquid storage cabin, the filtering cabin and the detection cabin are sequentially communicated, a liquid inlet end of the liquid storage cabin is opposite to the sample inlet, and the detection cabin is opposite to the observation port. Absorb the urine through straw or other devices, through the introduction port with the urine injection into detection mechanism, the urine enters into the stock solution cabin after, can follow the stock solution cabin and flow into in the filtration cabin in order, the filtration cabin filters the urine, the purification urine after getting rid of impurity can enter into the detection cabin, the detection cabin carries out biochemical color reaction to the urine and detects, the testing result observes through the viewing aperture, compares through testing result and contrast card, the range estimation obtains the result. The whole process is simple and quick to operate, and the testee can carry out the self-examination of the urine galactose at home.
Description
Technical Field
The utility model relates to an external diagnostic reagent technical field, concretely relates to urine galactose self-test device and system.
Background
Lactose intolerance is lactose digestive disorder, and the main reason of the disorder is that the mucous membrane surface of the small intestine lacks lactase, so that lactose cannot be further decomposed into glucose and galactose for absorption, and the lactose is accompanied by a series of clinical symptoms such as abdominal distension, diarrhea and abdominal pain. The expression of lactase gene is influenced by age, and is shown in that the lactase activity gradually decreases with the age until the lactase activity disappears. Therefore, the elderly are at greater risk of lactose intolerance and, in addition, diarrhea caused by lactose intolerance is also an important type of infantile diarrhea disease, and thus, lactose intolerance has become a common term in many nutritional tests. Current routine laboratory tests for lactose intolerance are hydrogen breath test, stool routine test, reducing sugar test, and urine galactose test. Wherein, the galactose oxidase method is one of the technologies for detecting urine galactose by dry chemical biochemical method. The principle is that galactose oxidase catalyzes galactose to generate aldohexose and hydrogen peroxide, and the hydrogen peroxide catalyzes 3.5 dichloro dihydroxy benzene sulfonic acid and 4 amino antipyrine to synthesize the red quinine compound in the presence of the peroxidase. (ZL 202111496295.2) the amount of hydrogen peroxide produced is proportional to the concentration of urinary galactose so that the amount of urinary galactose can be qualitatively or quantitatively measured. The method has the characteristics of low cost, simple operation, quick detection and no need of professional medical knowledge, and is a preferred method for quickly and automatically detecting (self-test) urine galactose. At present, no urinary galactosase detection device suitable for home self-test exists in the market, and self-testers need to go to hospitals regularly to check the state and prognosis condition of lactose intolerance, so that medical resources are wasted, and inconvenience is brought to the self-testers.
SUMMERY OF THE UTILITY MODEL
Therefore, the to-be-solved technical problem of the utility model lies in overcoming the urine galactozyme detection device who is not applicable to family's self-test among the prior art, and the person of self-test need regularly go to the state and the prognosis condition that the hospital checked the lactose intolerance, both extravagant medical resources cause inconvenient defect again for the person of self-test to a urine galactose self-test device and system are provided.
In order to solve the problem, the utility model provides a urine galactose self-test device, include:
the device comprises a shell, a liquid inlet, a liquid outlet and a liquid outlet, wherein the shell is a hollow cavity, and two ends of one side of the shell are respectively provided with a sample inlet and an observation port;
the detection mechanism is arranged in the cavity of the shell and is fixedly connected with the shell, the detection mechanism comprises a liquid storage cabin, a filtering cabin and a detection cabin, the liquid storage cabin, the filtering cabin and the detection cabin are sequentially communicated, a liquid inlet end of the liquid storage cabin is opposite to the sample inlet, and the detection cabin is opposite to the observation port.
Further, the filter capsule comprises an activated carbon layer and a filter screen layer, and the filter screen layer surrounds the activated carbon layer.
Further, the pore diameter of the filter screen layer is smaller than the particle pore diameter of the activated carbon layer.
Furthermore, the inside of the liquid storage cabin is provided with diversion paper.
Furthermore, the detection cabin is provided with a detection pad, and the detection pad is provided with a color development piece.
Furthermore, the detection pad is made of NC membrane or chromatography paper.
Further, the color developing part comprises a dry chemical color developing pad and biochemical color developing reagent freeze-dried powder.
Further, still be provided with gas storage tank and waste liquid pond in the casing, the both ends of waste liquid pond respectively through transfer passage with detect cabin and gas storage tank are connected, just detect cabin, waste liquid pond and gas storage tank and be linked together.
The utility model also provides a urine galactose self-test system, include:
a centrifuge;
the centrifugal support is arranged inside the centrifugal machine and is movably connected with the centrifugal machine, a plurality of unit cabins are arranged on the centrifugal support, and the unit cabins are used for placing the urine galactose self-testing device.
The utility model has the advantages of it is following:
1. utilize the technical scheme of the utility model, carry out from time measuring when the self-test person to the galactose of urine, absorb the urine through straw or other device, then inject the urine into detection mechanism through the introduction port on the casing, the stokehold among the detection mechanism is relative with the introduction port on the casing, the urine enters into behind the stokehold, because the stokehold, filter cabin and detection cabin communicate in order, so the urine can flow in the filter cabin in order from the stokehold, the filter cabin filters the urine, the purification urine after getting rid of impurity can enter into in the detection cabin in order, the detection cabin carries out biochemical color reaction to the urine and detects, and the testing result observes through the observation port, compare with the contrast card through the testing result, can acquire the situation of galactose in the urine. The whole process is simple and quick to operate, and the testers can carry out the self-examination of the urine galactose at home, so that the convenience is improved.
2. The filter cabin includes activated carbon layer and filter screen layer, and the filter screen layer surrounds the activated carbon layer, and after initial urine sample entered into the filter cabin from the stock solution cabin, earlier filtered initial urine sample through the filter screen layer, then impurity in the urine is got rid of to the urine rethread activated carbon layer after the filtration, acquires the purification urine for the result of test is more accurate, has reduced the interference of other impurity in the urine to the test result, has improved the accuracy.
3. The detection cabin is equipped with the detection pad, and the detection pad is equipped with the color development piece, and after the urine entered into the detection cabin, the urine can produce biochemical reaction with the color development piece that detects on the pad, and the colour of color development piece can change this moment, observes the colour of color development piece from the viewing aperture to compare it with the colour on the contrast card, be printed on the contrast card with the color development gradient of different concentration galactose, find the matching color, just can acquire the galactose concentration that this colour corresponds.
4. After urine enters the detection cabin from the liquid storage cabin filtering cabin, redundant liquid enters the waste liquid pool through the conveying channel, the volume of the urine sample entering the detection cabin can be equal, air pressure difference is avoided to occur, urine backflow is caused, gas can enter in the test process, and redundant gas enters the gas storage pool through the conveying channel.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 shows a schematic structural diagram of the urine galactose self-testing device of the present invention;
fig. 2 shows a schematic perspective view of the urine galactose self-testing device of the present invention;
FIG. 3 is a schematic structural diagram of the waste liquid tank and the gas storage tank of the urine galactose self-testing device of the present invention;
FIG. 4 shows a schematic structural diagram of the centrifugal rack of the urine galactose self-testing system of the present invention;
FIG. 5 shows a schematic structural diagram of the centrifugal rack 11 of the urine galactose self-testing system for placing the urine galactose self-testing device;
description of reference numerals:
1. a housing; 2. a sample inlet; 3. an observation port; 4. a detection mechanism; 5. a liquid storage tank; 6. a filtration compartment; 7. a detection cabin; 8. an activated carbon layer; 9. a screen layer; 10. a detection pad; 11. a centrifugal support; 12. a unit compartment; 13. a gas storage tank; 14. a waste liquid tank; 15. a delivery channel.
Detailed Description
The technical solution of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected" and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
Furthermore, the technical features mentioned in the different embodiments of the invention described below can be combined with each other as long as they do not conflict with each other.
Referring to fig. 1 and 2, the utility model provides a urine galactose self-test device, include:
the device comprises a shell 1, wherein the shell 1 is a hollow cavity, and a sample inlet 2 and an observation port 3 are respectively arranged at two ends of one side of the shell 1;
Utilize the technical scheme of the utility model, carry out from time measuring when the galactose of self-test person to the urine, absorb the urine through straw or other devices, then inject into detection mechanism 4 through introduction port 2 on the casing 1 with the urine, stock solution cabin 5 in the detection mechanism 4 is relative with introduction port 2 on the casing 1, the urine enters into stock solution cabin 5 after, because stock solution cabin 5, filter cabin 6 and detection cabin 7 communicate in order, so the urine can flow into in filtering cabin 6 in order from stock solution cabin 5, filter cabin 6 filters the urine, the purification urine after getting rid of impurity can enter into detection cabin 7 in order, detection cabin 7 carries out biochemical color reaction to the urine and detects, and the testing result observes through viewing aperture 3, compare through testing result and contrast card, can acquire the situation of galactose in the urine. The whole process is simple and quick to operate, and a self-tester can perform self-checking on the urine galactose at home, so that the convenience is improved.
In this embodiment, casing 1 is hollow cavity, and the both ends of casing 1 one side are equipped with introduction port 2 and viewing aperture 3 respectively, and the reservoir 5 in detection mechanism 4, it communicates with each other to filter cabin 6 and detection cabin 7 gas-liquid, gas and liquid can be via reservoir 5, filter cabin 6 and detection cabin 7 flow, inject the urine into detection mechanism 4 through inlet 2 on casing 1, reservoir 5 in detection mechanism 4 is relative with introduction port 2 on the casing 1, the urine enters into reservoir 5 after, use inlet 2 lid to cover inlet 2 tightly, prevent that outside air or impurity from entering into detection mechanism 4, the accuracy of detection has been improved.
The filter cabin 6 comprises an activated carbon layer 8 and a filter screen layer 9, the filter screen layer 9 surrounds the activated carbon layer 8, and the pore size of the filter screen layer 9 is smaller than the particle pore size of the activated carbon layer 8.
In this embodiment, the filter cabin 6 includes activated carbon layer 8 and filter screen layer 9, filter screen layer 9 surrounds activated carbon layer 8, after the initial urine sample enters into filter cabin 6 from stock solution 5, filter the initial urine sample through filter screen layer 9 earlier, then the urine after the filtration gets rid of the impurity in the urine through activated carbon layer 8 again, acquire the purification urine, make the result of test more accurate, other impurity in the urine has been reduced to the interference of test result, the accuracy has been improved. In other embodiments, other materials capable of filtering urine are suitable for the present invention, and are not limited herein.
The liquid storage cabin 5 is internally provided with diversion paper.
In this embodiment, 5 inside water conservancy diversion papers that are equipped with of stock solution cabin can carry out the water conservancy diversion to initial urine sample for the urine can enter into filter cabin 6, prevents the urine refluence.
The detection cabin 7 is provided with a detection pad 10, and the detection pad 10 is provided with a color development piece.
In this embodiment, detect the cabin 7 and be equipped with detection pad 10, detect pad 10 and be equipped with the color development piece, after urine enters into detection cabin 7, the urine can produce biochemical reaction with the color development piece that detects on the pad 10, the color of color development piece can change this moment, observe the color of color development piece from viewing aperture 3, and compare its colour with the contrast card on, the contrast card is printed on the color development gradient of different concentration galactose, find the matching color, just can acquire the galactose concentration that this colour corresponds.
The detection pad 10 is made of NC film or chromatography paper.
The color development part comprises a dry chemical color development pad and biochemical color development reagent freeze-dried powder.
In this embodiment, the solid-phase dry chemical color developing pad can generate biochemical color developing reaction with galactose, the color developing wavelength is within the visible wavelength range and can be identified by naked eyes, a self-tester can directly compare with a contrast card according to the observed color, and the biochemical color developing reagent freeze-dried powder can also play the same technical effect. In other embodiments, other substances that can react biochemically with galactose in urine and produce changes are suitable for use in the present invention.
In this embodiment, a front channel is disposed between the liquid storage compartment 5 and the filter compartment 6, the gas and the liquid enter the filter compartment 6 from the liquid storage compartment 5 through the front channel, a rear channel is disposed between the filter compartment 6 and the detection compartment 7, and the gas and the liquid enter the detection compartment 7 from the filter compartment 6 through the rear channel, wherein the front channel and the rear channel are both cylindrical, and the diameter of the front channel is larger than that of the rear channel, so that the gas can circulate in the detection mechanism 4 besides the gas can circulate.
In this embodiment, the housing 1 is further provided with an air storage tank 13 and a waste liquid tank 14, two ends of the waste liquid tank 14 are respectively connected with the detection chamber 7 and the air storage tank 13 through a conveying channel 15, and the detection chamber 7, the waste liquid tank 14 and the air storage tank 13 are communicated. During the test, the excess gas in the test chamber 7 enters the gas reservoir 13 through the transfer passage 15, and the excess liquid enters the waste liquid reservoir 14 through the transfer passage 15.
The material of the shell 1 and the detection mechanism 4 is inert high polymer material.
In this embodiment, the inert high polymer material is a biomedical material that can be stable in a biological environment and does not or only weakly react chemically, and is mainly inert bioceramic materials and medical metal and alloy materials. Since there is no completely inert material in practice, the biologically inert material is not substantially chemically reactive in the body, and the bonding with the tissue is mainly due to the growth of the tissue into its rough and uneven surface to form a mechanical interlocking, i.e., morphological bonding, so that the use of this material reduces the chemical reaction with urine and improves the accuracy of the detection.
The practical application is illustrated as follows:
the testee A absorbs 300ul of urine, and after the urine is injected into the liquid storage cabin 5 through the sample inlet 2, the cover of the sample inlet 2 is closed. Shaking the shell up and down for 30 times, standing the end of the shell 1 with the sample inlet 2 vertically upwards for 10 minutes, observing the color from the observation port 3, comparing the color with the color on the comparison color chart, judging the result, wherein the observed color is similar to the color with the galactose concentration of 1mmol/L on the color chart, and judging the urine galactose concentration to be 1mmol/L. Or the urine is put into the soup self-testing device and sent into a spectrophotometric colorimeter to measure the colorimetric value.
Referring to fig. 3, the utility model also provides a urine galactose self-test system, include:
a centrifuge;
In this embodiment, be equipped with a plurality of unit cabins 12 on centrifugal support 11, unit cabin 12 is used for placing the aforesaid urine galactose self-test device, then place it and carry out the centrifugation on centrifuge for the urine carries out biochemical reaction from stock solution cabin 5 entering into fast in the detection cabin 7, and a batch can detect a plurality of urine galactose self-test devices, has improved detection efficiency.
The specific operation is as follows:
and opening a cover of the injection port 2 on the injection port 2, injecting the initial urine sample into the liquid storage cabin 5 from the injection port 2 of the liquid storage cabin 5, and closing the cover of the injection port 2. The whole urine galactose self-testing device is placed in a unit cabin 12 in a centrifugal support 11, the centrifugal support 11 is balanced before centrifugation, after all sides are of equal weight, a single detection unit is arranged in the unit cabin 12 placed in the centrifugal support 11 in the direction that an observation port 3 is far away from a centrifuge shaft and a sample inlet 2 is close to the centrifuge shaft. Centrifuge bracket 11 is put into centrifuge and is centrifuged, and 11 centers of centrifuge bracket correspond the centrifuge crankshaft, under centrifugal force's drive, urine impurity is got rid of through filtering cabin 6 to initial urine sample, the purification urine after getting rid of urine impurity enters into detection cabin 7 from filtering cabin 6 under the effect of centrifugal force, take place biochemical color reaction with the color development piece that sets up in detection cabin 7, the person of self-test can see reaction color development result via viewing aperture 3, carry out the colour with the contrast card and compare, acquire the situation of galactose concentration in the urine.
The practical application is illustrated as follows:
the testee A and B respectively use the straw to absorb 300ul urine, inject into stock solution cabin 5 via injection port 2 after, close injection port 2 lid, put into unit cabin 12 in centrifugal support 11. On the centrifugal bracket 11, the unit cabin 12 with the A sample and the unit cabin 12 with the B sample are opposite, after the centrifugal machine is centrifuged for 5 minutes at 1500rpm, the color is observed from the observation port 3, and compared with the color on the contrast color card, the result is judged. The color of the observation opening 3 is similar to the color of the galactose concentration of 1mmol/L on the colorimetric card, and the urine galactose concentration is judged to be 1mmol/L. The color in the observation port 3 was observed to be similar to the color of 1.5mmol/L of galactose on the colorimetric card, and the urinary galactose concentration was judged to be 1.5mmol/L. Or the urine galactose self-testing device in the unit chamber 12 is taken out from the centrifugal bracket 11 and sent into a spectrophotometric colorimeter to measure a colorimetric value.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications derived therefrom are intended to be within the scope of the invention.
Claims (9)
1. A urinary galactose self-testing device, comprising:
the device comprises a shell (1), wherein the shell (1) is a hollow cavity, and a sample inlet (2) and an observation port (3) are respectively arranged at two ends of one side of the shell (1);
detection mechanism (4), detection mechanism (4) are located in the cavity of casing (1), and with casing (1) fixed connection, detection mechanism (4) are including liquid storage cabin (5), filtration cabin (6) and detection cabin (7), liquid storage cabin (5) filter cabin (6) with detect cabin (7) and communicate in order, the feed liquor end of liquid storage cabin (5) with introduction port (2) are relative, detect cabin (7) with observation port (3) are relative.
2. The urinary galactose self-testing device according to claim 1, wherein the filter compartment (6) comprises an activated carbon layer (8) and a filter screen layer (9), the filter screen layer (9) surrounding the activated carbon layer (8).
3. The urinary galactose self-testing device according to claim 2, wherein the pore size of the filter layer (9) is smaller than the particle pore size of the activated carbon layer (8).
4. The urinary galactose self-testing device according to claim 1, wherein a diversion paper is arranged inside the liquid storage tank (5).
5. The urinary galactose self-testing device according to claim 1, characterized in that the detection chamber (7) is provided with a detection pad (10), and the detection pad (10) is provided with a color developing member.
6. The urinary galactose self-testing device according to claim 5, wherein the material of the detection pad (10) comprises NC membrane and chromatography paper.
7. The urinary galactose self-testing device of claim 5, wherein the color developing member comprises a dry chemical color developing pad, a biochemical color developing reagent freeze-dried powder.
8. The urinary galactose self-testing device according to claim 1, wherein an air storage tank (13) and a waste liquid tank (14) are further disposed in the housing (1), two ends of the waste liquid tank (14) are respectively connected to the detection chamber (7) and the air storage tank (13) through a conveying channel (15), and the detection chamber (7), the waste liquid tank (14) and the air storage tank (13) are communicated.
9. A urinary galactose self-testing system, comprising:
a centrifuge;
the centrifugal support (11) is arranged in the centrifuge and movably connected with the centrifuge, a plurality of unit cabins (12) are arranged on the centrifugal support (11), and the unit cabins (12) are used for placing the urine galactose self-testing device according to any one of claims 1-9.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202222599195.9U CN218445154U (en) | 2022-09-29 | 2022-09-29 | Urine galactose self-testing device and system |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202222599195.9U CN218445154U (en) | 2022-09-29 | 2022-09-29 | Urine galactose self-testing device and system |
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| CN218445154U true CN218445154U (en) | 2023-02-03 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116640655A (en) * | 2023-05-26 | 2023-08-25 | 北京中生金域诊断技术股份有限公司 | Portable urine galactose detection kit stored at normal temperature, reaction liquid and preparation method thereof |
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- 2022-09-29 CN CN202222599195.9U patent/CN218445154U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116640655A (en) * | 2023-05-26 | 2023-08-25 | 北京中生金域诊断技术股份有限公司 | Portable urine galactose detection kit stored at normal temperature, reaction liquid and preparation method thereof |
| CN116640655B (en) * | 2023-05-26 | 2024-03-29 | 北京中生金域诊断技术股份有限公司 | Portable urine galactose detection kit stored at normal temperature, reaction liquid and preparation method thereof |
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