CN218382842U - Full-automatic glycosylated hemoglobin detection device - Google Patents

Abstract

The utility model discloses a full automatization glycated hemoglobin detection device, including lateral shifting mechanism, longitudinal movement mechanism, move liquid mechanism, move back rifle mechanism, kit subassembly and detection mechanism, the kit subassembly includes the reagent box seat, kit body and liquid-transfering gun, the liquid-transfering gun is placed on the kit body, the kit body is installed on the reagent box seat, the reagent box seat is installed on lateral shifting mechanism's removal portion, longitudinal movement mechanism's fixed part is installed on lateral shifting mechanism's fixed part, move back the fixed part of rifle mechanism and install on longitudinal movement part's removal portion, liquid-transfering mechanism includes the force pump, trachea and the air guide inserted bar of pegging graft with the liquid-transfering gun, air guide inserted bar upper end is fixed in on the fixed part of moving back rifle mechanism, the air guide inserted bar activity runs through on the removal portion of moving back rifle mechanism, the air guide inserted bar is cavity form, tracheal both ends are force pump and inserted bar connection respectively. The device simple structure, convenient operation can realize the full automatization to glycated haemoglobin measuring.

Description

Full-automatic glycosylated hemoglobin detection device

Technical Field

The utility model relates to a glycated haemoglobin detects technical field, concretely relates to full automatization glycated haemoglobin detection device.

Background

Glycated hemoglobin (HbA 1 c) is an important index for clinical examination, and standardization and marketing studies of the detection technology are both regarded as important at home and abroad. The glycosylated hemoglobin is formed by irreversible combination of blood sugar and hemoglobin, the content of the glycosylated hemoglobin in the body is closely related to the content of the blood sugar, and the glycosylated hemoglobin is much stronger than the blood sugar in stability. Can reflect the blood sugar level of the body in a long time, has stable and reliable indexes and has great significance in the diabetes diagnosis.

The glycated hemoglobin detection instrument that uses in the market at present degree of automation is generally lower, and too many steps need manual operation in the testing process, cause complex operation to the precision of adding reagent also can reduce, leads to result precision not high.

For example, patent No. CN215641310U discloses a full-automatic glycosylated hemoglobin meter, which includes a box body; the device comprises a protection box, a threaded rod, a trapezoidal groove, a trapezoidal clamping block, test paper, reagent threads, a limiting groove, a limiting block, an anti-slip pad, a bearing, a motor, a gear, a rotating roller, a rack, a handle, a square hole, dripping water and an observation port; the test paper is put into the box artificially, arrange two trapezoidal clamp blocks in, it is rotatory that rotatory handle drives the threaded rod this moment, trapezoidal clamp block is fixed with the test paper step up along the dovetail groove, back starter motor utilizes transmission to drip reagent bottle slope to the test paper on, this glycated haemoglobin appearance although can be more convenient completion glycated haemoglobin appearance's detection, but artifical participation degree is high, and can't ensure higher measurement accuracy through the mode of motor slope reagent bottle drippage reagent, unsuitable demand that needs the high accuracy.

Disclosure of Invention

In order to solve the problems existing in the prior art, the utility model provides a full automatization glycosylated hemoglobin detection device, the device simple structure, convenient operation can realize the full automatization detection to glycosylated hemoglobin.

Realize the utility model discloses the technical scheme that above-mentioned purpose adopted does:

a full-automatic glycosylated hemoglobin detection device comprises a transverse moving mechanism, a longitudinal moving mechanism, a liquid transferring mechanism, a gun returning mechanism, a kit component and a detection mechanism, wherein the kit component comprises a kit body and a kit, the kit body comprises a kit body and a liquid transferring gun, the liquid transferring gun is placed on the kit body, the kit body is installed on a moving part of the transverse moving mechanism, the kit body can reciprocate in the horizontal direction, a fixing part of the longitudinal moving mechanism is installed on a fixing part of the transverse moving mechanism, a fixing part of the gun returning mechanism is installed on a moving part of a longitudinal moving part, the gun returning mechanism can reciprocate in the vertical direction, the liquid transferring mechanism comprises a pressure pump, an air pipe and an air guide inserted bar which is connected with the liquid transferring gun, the air guide inserted bar is fixed on the fixing part of the gun returning mechanism, the air guide inserted bar movably penetrates through the moving part of the gun returning mechanism, the moving part of the gun returning mechanism can reciprocate in the vertical direction, the air guide inserted bar is hollow, and two ends of the air pipe are respectively connected with the pressure pump and the air guide inserted bar;

when the kit body is located at the initial position, the air guide inserted link is located right above the kit body, and when the kit body moves to the detection position, the detection mechanism can detect the glycosylated hemoglobin in the kit body.

The horizontal moving mechanism comprises a supporting base plate, a horizontal motor support, a horizontal driving pulley, a horizontal driven pulley, a horizontal pulley shaft and a horizontal belt, the horizontal motor is installed on the supporting base plate through the horizontal motor support, the horizontal driving pulley is installed on the output end of the horizontal motor, the lower end of the horizontal pulley shaft is installed on the supporting base plate, the horizontal pulley shaft is perpendicular to the supporting base plate, the horizontal driven pulley is sleeved on the horizontal pulley shaft, the horizontal driving pulley is connected with the horizontal driven pulley through the horizontal belt, and the reagent box seat is fixed on the horizontal belt.

The transverse moving mechanism further comprises a transverse guide rail, a transverse sliding block and a transverse zero-returning sensor used for sensing that the reagent box body reaches an initial position, the transverse guide rail is installed on the supporting base plate and is parallel to the moving direction of the transverse belt, the transverse sliding block is installed on the transverse guide rail, the reagent box seat is fixed on the transverse sliding block, and the transverse zero-returning sensor is fixed on the supporting base plate.

The reagent box seat is provided with a slot matched with the reagent box body, and the reagent box body is spliced with the reagent box seat through the slot.

The longitudinal mechanism comprises a longitudinal support plate, a longitudinal motor, a longitudinal driving belt wheel, a longitudinal driven belt wheel, a longitudinal belt wheel shaft, a longitudinal belt, a longitudinal guide rail, a longitudinal sliding block and a longitudinal zero-returning sensor used for returning the connecting plate to the initial position, wherein the bottom of the longitudinal support plate is fixed on the support base plate, the longitudinal support plate is perpendicular to the support base plate, the longitudinal motor is installed at the bottom of the longitudinal support plate, one end of the longitudinal belt wheel shaft is installed at the top of the longitudinal support plate, the longitudinal belt wheel shaft is perpendicular to the longitudinal support plate, the longitudinal driving belt wheel is sleeved on an output shaft of the longitudinal motor, the longitudinal driven belt wheel is sleeved on the longitudinal belt wheel shaft, the longitudinal driving belt wheel is connected with the longitudinal driven belt wheel through the longitudinal belt, the longitudinal guide rail is installed on the longitudinal support plate, the longitudinal guide rail is parallel to the moving direction of the longitudinal belt, and the longitudinal sliding block is installed on the longitudinal guide rail.

Move back rifle mechanism include the linkage plate, move back the rifle motor, move back rifle motor support, the push pedal and move back the rifle lead screw, the linkage plate is the U type, the vertical setting of linkage plate, linkage plate middle part and vertical slider are connected, the opening of linkage plate is vertical backup pad dorsad, move back rifle motor support respectively with the both sides edge fixed connection of linkage plate, vertical belt runs through the space that moves back rifle motor support and linkage plate enclose, and vertical belt is connected with the both sides part of linkage plate respectively, move back the rifle motor and install on moving back rifle motor support, move back the rifle lead screw including moving back the rifle screw rod and moving back the rifle nut, move back the upper end of rifle screw rod and be connected with the output that moves back the rifle motor, move back the rifle nut cover and locate on moving back the rifle lead screw, the push pedal horizontal cover is located on moving back the rifle nut, the air guide inserted bar runs through the push pedal, and air guide inserted bar and push pedal clearance fit, the force pump is the plunger pump.

Move back rifle mechanism still include the deflector, the deflector level sets up, the deflector is fixed in moves back on the rifle motor support, the last pot head of air guide inserted bar is equipped with the mounting disc, the air guide inserted bar runs through the deflector, the air guide inserted bar passes through mounting disc and deflector fixed connection, is equipped with the guiding hole on the deflector, moves back rifle lead screw and guiding hole clearance fit.

The kit body on be equipped with along the sample hybrid chamber of straight line distribution, rifle head chamber, first reagent chamber, second reagent chamber, wash liquor chamber and detection chamber, the sample hybrid chamber, rifle head chamber, first reagent chamber, second reagent chamber, wash liquor chamber and detection chamber are isolated each other, the kit still includes the sampler of cavity form, the sampler comprises handle portion and flowing back portion, handle portion is the form of expanding, the flowing back portion is the toper, the symmetry is equipped with a pair of first drainage hole on the middle part of flowing back portion, be equipped with the second outage on the tip of drainage portion, the flowing back portion is located the sample hybrid chamber, the opening of sealed sample hybrid chamber is blocked to the main aspects of drainage portion lateral wall, handle portion and the main aspects port intercommunication of drainage portion, the liquid-transfering gun is accomodate in rifle head chamber, be equipped with in the detection chamber and place the baffle and separate for analysis chamber and waste liquid cavity, it is equipped with the filtration hole to place baffle central authorities, the lid has closed the gland on the analysis chamber opening, the gland central authorities are equipped with the analysis hole, the axis of filtration hole is the same with the analysis hole.

The middle part symmetry of drainage portion be equipped with a pair of first drainage hole, the kit body is squarely, and the kit body is the platykurtic, the sample hybrid chamber, the rifle head chamber, first reagent chamber, the second reagent chamber, wash liquid chamber and detection chamber distribute along the length direction of kit body in proper order, and the rifle head chamber, first reagent chamber, the second reagent chamber, the opening of wash liquid chamber and detection chamber all is located a surface of kit body, the joint has hollow rifle head cover on the rifle head chamber, the pipetting gun runs through the rifle head cover, and pipetting gun and rifle head cover joint, be equipped with on the opposite side of kit body and be platelike handle, the handle is close to the sample hybrid chamber, and handle and sample hybrid chamber opening distribute on same straight line.

The detection mechanism including detecting regulation support, light screen, detector, detect the support including supporting the regulation riser and supporting the regulation diaphragm, support on the regulation riser is fixed in the supporting baseplate, support and be equipped with a plurality of regulation holes along vertical direction on the regulation riser, a plurality of regulation holes distribute along the straight line, be equipped with rectangular hole on one side of supporting the regulation diaphragm, support the regulation diaphragm and pass through fastening bolt and support and adjust the riser and be connected, the light screen is fixed in and supports on the bottom of adjusting the diaphragm opposite side, and the light screen perpendicular to supports the regulation diaphragm, the detector is fixed in on the light screen.

Compared with the prior art, the beneficial effects and advantages of the utility model reside in that:

1. the device has the advantages of simple structure, ingenious and reasonable design, small volume, small occupied area and relatively low cost, and is suitable for large-area popularization and application in medical institutions.

2. The device degree of automation is high, at whole automation mechanized operation of testing process, does not need manual operation, and reagent adds accurate control moreover, and consequently, the testing result is accurate reliable, and the precision is high, and repeatability is good.

Drawings

FIG. 1 is a schematic structural view of a fully automated glycated hemoglobin measurement apparatus.

Fig. 2 is a schematic structural view of the lateral movement mechanism.

Fig. 3 is an assembly view of the longitudinal movement mechanism and the gun retreating mechanism.

Fig. 4 is a schematic structural view of the longitudinal movement mechanism.

Fig. 5 is a schematic structural diagram of the gun retreating mechanism.

Fig. 6 is a schematic structural view of the detection mechanism.

FIG. 7 is a schematic diagram of the structure of the kit.

Fig. 8 is a schematic view of the internal structure of the cartridge body.

Fig. 9 is a schematic structural diagram of a pipette.

Wherein, 1-supporting the bottom plate; 2-a transverse motor; 3-transverse motor support; 4-a transverse driving pulley; 5-a transverse driven pulley; 6-transverse pulley shaft; 7-transverse belts; 8-transverse guide rails; 9-transverse sliding block; 10-transverse return-to-zero sensor, 11-longitudinal support plate; 12-a longitudinal motor; 13-a longitudinal driving pulley; 14-a longitudinal driven pulley; 15-longitudinal pulley shaft; 16-longitudinal belt; 17-connector tiles; 18-gun withdrawing motor; 19-gun withdrawing motor support; 20-pushing the plate; 21-withdrawing the gun screw; 22-gun nut withdrawal; 23-a guide plate; 24-a longitudinal return to zero sensor; 25-a reagent kit holder; 26-kit body; 27-a pipette; 28-a sample mixing chamber; 29-the gun head cavity; 30-a first reagent chamber; 31-a second reagent chamber; 32-a wash chamber; 33-a sampler: 321-handle part, 322-liquid discharge part, 323-first liquid discharge hole, 324-second liquid discharge hole; 34-detection chamber: 341-placing partition, 342-analysis chamber, 343-waste chamber, 344-gland, 345-analysis hole, 346-filtration hole; 35-supporting an adjusting vertical plate; 36-supporting the adjusting transverse plate; 37-elongated holes; 38-an adjustment aperture; 39-a visor; 40-a plunger pump; 41-air guide inserted bar; 42-longitudinal guide rail; 43-longitudinal slide; 44-a detector; 45-gun head cover, 46-handle.

Detailed Description

The present invention will be described in detail with reference to the accompanying drawings.

The structure of the fully automated glycated hemoglobin measurement apparatus provided in this embodiment is shown in fig. 1, and includes a lateral movement mechanism, a longitudinal movement mechanism, a pipetting mechanism, a withdrawal mechanism, a reagent kit assembly, a measurement mechanism, and a controller.

As shown in fig. 2, the lateral movement mechanism includes a support base plate 1, a lateral motor 2, a lateral motor bracket 3, a lateral driving pulley 4, a lateral driven pulley 5, a lateral pulley shaft 6, a lateral belt 7, a lateral guide rail 8, a lateral slider 9, and a lateral zero-return sensor 10. The transverse motor 2 is arranged on the supporting base plate 1 through a transverse motor bracket 3, and the transverse driving belt wheel 4 is sleeved on an output shaft of the transverse motor 2. The lower end of a transverse belt wheel shaft 6 is installed on the supporting base plate 1, the transverse belt wheel shaft 6 is perpendicular to the supporting base plate 1, a transverse driven belt wheel 5 is sleeved on the transverse belt wheel shaft 6, and a transverse driving belt wheel 4 is connected with the transverse driven belt wheel 5 through a transverse belt 7. The transverse guide rail 8 is arranged on the supporting bottom plate 1, the transverse guide rail 8 is parallel to the moving direction of the transverse belt 7, and the transverse sliding block 9 is arranged on the transverse guide rail 8. The transverse zero-return sensor 10 is fixed on the supporting bottom plate 1, and when the reagent box body 26 reaches the initial position, the transverse zero-return sensor 10 receives a signal and transmits the signal to the controller.

As shown in fig. 3-4, the longitudinal mechanism includes a longitudinal support plate 11, a longitudinal motor 12, a longitudinal driving pulley 13, a longitudinal driven pulley 14, a longitudinal pulley shaft 15, a longitudinal belt 16, a longitudinal zero-return sensor 24, a longitudinal guide rail 42, and a longitudinal slider 43. The bottom of the longitudinal support plate 11 is fixed on the support base plate 1, the longitudinal support plate 11 is perpendicular to the support base plate 1, and the longitudinal motor 12 is installed on the bottom of the longitudinal support plate 11. One end of the longitudinal pulley shaft 15 is mounted on top of the longitudinal support plate 11, the longitudinal pulley shaft 15 being perpendicular to the longitudinal support plate 11. The longitudinal driving pulley 13 is sleeved on an output shaft of the longitudinal motor 12, the longitudinal driven pulley 14 is sleeved on a longitudinal pulley shaft 15, and the longitudinal driving pulley 13 is connected with the longitudinal driven pulley 14 through a longitudinal belt 16. The longitudinal guide rail 42 is mounted on the longitudinal support plate 11, the longitudinal guide rail 42 is parallel to the moving direction of the longitudinal belt 16, and the longitudinal slider 43 is mounted on the longitudinal guide rail 42. A longitudinal zero-return sensor 24 is fixed to the longitudinal support plate 11, and when the connector tile 17 returns to the initial position, the longitudinal zero-return sensor 24 receives a signal and transmits the signal to the controller.

As shown in fig. 3 and 5, the gun withdrawing mechanism comprises a connecting plate 17, a gun withdrawing motor 18, a gun withdrawing motor bracket 19, a push plate 20, a gun withdrawing screw rod and a guide plate 23. The connector tiles 17 are U-shaped and the connector tiles 17 are arranged vertically with the central portion of the connector tiles 17 attached to the longitudinal slider 43 and the opening of the connector tiles 17 facing away from the longitudinal support plate 11. Move back rifle motor support 19 respectively with the both sides edge fixed connection of linking plate 17, vertical belt 16 runs through and moves back the space that rifle motor support 19 and linking plate 17 enclose, and vertical belt 16 is connected with the both sides part of linking plate 17 respectively, moves back rifle motor 18 and installs on moving back rifle motor support 19, and deflector 23 level sets up, and deflector 23 is fixed in and moves back rifle motor support 19 on, is equipped with the guiding hole on the deflector 23. The gun retreating screw rod comprises a gun retreating screw rod 21 and a gun retreating nut 22, the upper end of the gun retreating screw rod 21 is connected with the output end of the gun retreating motor 18, the gun retreating screw rod 21 penetrates through the guide hole, and the gun retreating screw rod 21 is in clearance fit with the guide hole. The gun withdrawing nut 22 is sleeved on the gun withdrawing screw rod 21, the push plate 20 is horizontally sleeved on the gun withdrawing nut 22, and the push plate 20 is positioned under the guide plate 23. The gun retreating motor 18 rotates, the gun retreating motor 18 drives the gun retreating screw rod 21 to rotate, the gun retreating screw rod 21 drives the gun retreating nut 22 to rotate while rotating, the gun retreating nut 22 moves in the vertical direction while rotating, and the gun retreating nut 22 drives the push plate 20 to move in the vertical direction.

The pipetting mechanism comprises a plunger pump 40, an air pipe and an air guide inserted rod 41 inserted with the pipetting gun. The air guide inserted bar 41 is hollow, a mounting disc is sleeved at the upper end of the air guide inserted bar 41, the air guide inserted bar 41 penetrates through the guide plate 23, and the air guide inserted bar 41 is fixedly connected with the guide plate 23 through the mounting disc. The air guide inserted bar 41 penetrates through the push plate 20, and the air guide inserted bar 41 is in clearance fit with the push plate 20. The plunger pump 40 is arranged on the supporting bottom plate 1, and the two ends of the air pipe are respectively connected with the plunger pump 40 and the air guide inserted bar 41. The longitudinal motor 12 rotates, the longitudinal motor 12 drives the longitudinal belt 16 to move in the vertical direction, the longitudinal belt 16 drives the connecting plate 17 to move in the vertical direction, the connecting plate 17 drives the gun withdrawing motor support 19 to move in the vertical direction, the longitudinal motor support 19 drives the guide plate 23 to move in the vertical direction, and the guide plate 23 drives the air guide inserted bar 41 to move in the vertical direction.

The reagent kit component comprises a reagent kit seat 25 and a reagent kit, wherein the reagent kit seat 25 is respectively fixed on the transverse belt 7 and the transverse sliding block 9. The reagent box seat 25 is provided with a slot matched with the reagent box body 26, and the reagent box body 26 is inserted into the reagent box seat 25 through the slot. The transverse motor 2 rotates, the transverse motor 2 drives the transverse belt 7 to move in the horizontal direction, the transverse belt 7 drives the reagent box seat 25 to move in the horizontal direction, and the reagent box seat 25 drives the reagent box body 26 to move in the horizontal direction.

As shown in fig. 7 to 8, the reagent cartridge includes a reagent cartridge body 26, a pipette gun 27, and a sampler 33, the reagent cartridge body 26 is square, and the reagent cartridge body 26 is flat. The reagent kit body 26 is sequentially provided with a sample mixing cavity 28, a gun head cavity 29, a first reagent cavity 30, a second reagent cavity 31, a washing liquid cavity 32 and a detection cavity 34 along the length direction, the sample mixing cavity 28, the gun head cavity 29, the first reagent cavity 30, the second reagent cavity 31, the washing liquid cavity 32 and the detection cavity 34 are distributed along a straight line, the sample mixing cavity 28, the gun head cavity 29, the first reagent cavity 30, the second reagent cavity 31, the washing liquid cavity 32 and the detection cavity 33 are isolated from each other, openings of the sample mixing cavity 28, the gun head cavity 29, the first reagent cavity 30, the second reagent cavity 31, the washing liquid cavity 32 and the detection cavity 33 are all located on one surface of the reagent kit body 26, and axes of the gun head cavity 29, the first reagent cavity 30, the second reagent cavity 31 and the washing liquid cavity 32 are all parallel to the width direction of the reagent kit body 26.

As shown in fig. 9, sampler 33 is hollow, sampler 33 is composed of handle 321 and drain 322, and handle 321 is expanded. The liquid discharging part 322 is in a cone shape, a pair of first liquid outlet holes 323 are symmetrically arranged at the middle part of the liquid discharging part 322, and a second liquid discharging hole 324 is arranged at the small end of the liquid discharging part. The liquid discharge part 322 is positioned in the sample mixing cavity 28, the large end of the side wall of the liquid discharge part 322 is clamped and sealed with the opening of the sample mixing cavity 28, the handle part 321 is communicated with the large port of the liquid discharge part 322, a pair of liquid outlet holes are formed in the middle of the liquid discharge part, liquid pumped into the sample mixing cavity through the plunger pump can flow out quickly, the situation that the pressure in the liquid discharge part is too high due to the fact that the liquid outlet hole in the small end of the liquid discharge part is too small is avoided, the liquid in the sampler submerges the pipette head to cause the contamination of the pipette head, when the pipette is used for transferring next reagent, the pipette needs to be cleaned, the operation complexity is increased, in addition, the pressure in the liquid part is too high, and the pipette can be jacked open to cause the liquid in the sampler to flow out. The hollow gun head sleeve 45 is clamped on the gun head cavity 29, the liquid transferring gun 27 penetrates through the gun head sleeve 45, and the liquid transferring gun 27 is clamped with the gun head sleeve 45.

A placing clapboard 341 is arranged in the detection cavity 34, the detection cavity 34 is separated into an analysis cavity 342 and a waste liquid cavity 343 by the placing clapboard 341, and the center of the placing clapboard 341 is provided with a filter hole 346. The analysis cavity 342 is covered with a gland 344 at the opening, the gland 344 is used for compressing and fixing the detection cotton, the center of the gland 344 is provided with an analysis hole 345, and the axes of the filter hole 346 and the analysis hole 345 are the same.

The other side of the kit body 26 is provided with a plate-shaped handle 46 which is close to the sample mixing cavity 28, and the openings of the handle 46 and the sample mixing cavity 28 are distributed on the same straight line, so that the handle 46 can be used for conveniently taking the kit.

As shown in fig. 6, the detection mechanism includes a detection regulation bracket, a light shielding plate 39, and a detector 44. The detection support comprises a supporting adjusting vertical plate 35 and a supporting adjusting transverse plate 36, the supporting adjusting vertical plate 35 is fixed on the supporting base plate 1, a plurality of adjusting holes 38 are formed in the supporting adjusting vertical plate 35 in the vertical direction, the adjusting holes 38 are distributed along a straight line, a strip hole 37 is formed in one side of the supporting adjusting transverse plate 36, and the supporting adjusting transverse plate 36 is connected with the supporting adjusting vertical plate 35 through a fastening bolt. The light shielding plate 39 is fixed on the bottom of the other side of the supporting adjustment cross plate 36, the light shielding plate 39 is perpendicular to the supporting adjustment cross plate 36, and the detector 44 is fixed on the light shielding plate 39.

The controller is respectively electrically connected with the longitudinal motor 12, the transverse motor 2, the gun withdrawing motor 18, the plunger pump 40 and the detector, and controls the working time point, the working time length and the working mode (such as forward rotation and reverse rotation of the motors) of the longitudinal motor 12, the transverse motor 2, the gun withdrawing motor 18, the plunger pump 40 and the detector.

The detection method of the full-automatic glycosylated hemoglobin detection device comprises the following steps:

1. a blood sample to be detected is placed in the sample mixing chamber 28, a reagent R1 is placed in the first reagent chamber 30, a reagent R2 is placed in the second reagent chamber 31, a cleaning solution is placed in the cleaning solution chamber 32, reaction cotton is placed on the placing partition plate 341 of the detection chamber 34, and the pressing cover 344 is closed;

2. placing the reagent kit body 26 on a reagent kit seat, starting the controller, the transverse motor 2, the longitudinal motor 12, the gun withdrawing motor 18, the plunger pump 40 and the detector, wherein in the whole process, the transverse motor 2, the longitudinal motor 12, the gun withdrawing motor 18, the plunger pump 40 and the detector are all automatically controlled by the controller, the controller detects whether the reagent kit body 26 and the air guide inserted bar 41 are located at initial positions, if the reagent kit body 26 and the air guide inserted bar 41 are not located at the initial positions, the transverse motor 2 and the longitudinal motor 12 start to work, the transverse motor 2 drives the reagent kit body 26 to reach the initial positions, the longitudinal motor 12 drives the air guide inserted bar 41 to reach the initial positions, and the longitudinal motor 12 stops working;

3. the transverse motor 2 continues to work, the transverse motor 2 drives the kit body 26 to move to a set distance, the liquid-transferring gun 27 is located right below the air guide inserted bar 41, the transverse motor 2 stops working, the longitudinal motor 12 starts working, the longitudinal motor 12 drives the air guide inserted bar 41 to move downwards to a set distance, and the air guide inserted bar 41 is inserted into the liquid-transferring gun 27;

4. the longitudinal motor 12 continues to work, the longitudinal motor 12 drives the liquid transfer gun 27 to move upwards to a set distance, the longitudinal motor 12 stops working, the transverse motor 2 starts working, the transverse motor 2 drives the reagent kit body 26 to move to a set distance, at this time, the first reagent chamber 30 is located right below the liquid transfer gun 27, the transverse motor 2 stops working, the longitudinal motor 12 starts working, the longitudinal motor 12 drives the liquid transfer gun 27 to move downwards to a set distance, the head of the liquid transfer gun 27 is located below the liquid level of the reagent R1, the longitudinal motor 12 stops working, the plunger pump 40 starts working, the reagent R1 is pumped into the liquid transfer gun to a set volume, the plunger pump 40 stops working, the longitudinal motor 12 starts working, the longitudinal motor 12 drives the liquid transfer gun 27 to move upwards to a set distance, the longitudinal motor 12 stops working, the transverse motor 2 starts working, the transverse motor 2 drives the reagent kit body 26 to move to a set distance, at this time, the liquid transfer gun 27 is located right above the sample mixing chamber 28, the transverse motor 2 stops working, the longitudinal motor 12 starts working, the longitudinal motor 12 drives the liquid transfer gun 27 to move downwards to a set distance, the liquid transfer gun 27 is inserted into the sampler 27, the sample mixing chamber 33 is clamped with the reagent pump 321, the reagent mixing chamber 12 starts working, the reagent pump 321 starts working;

5. the plunger pump 40 continues to work, the liquid in the mixed sample cavity 28 is extracted and the liquid is injected into the mixed sample cavity 28, the operations are repeated for a plurality of times, the blood sample and the reagent R1 are fully mixed, and the incubation is carried out for two minutes to wait for the full lysis of the blood sample;

6. according to the method of the steps 4 and 5, the reagent R2 is moved into the mixed sample cavity 28 by using the plunger pump 40, and after complete mixing and reaction, blue floccule is formed;

7. injecting blue floe onto the reaction cotton in the detection chamber 34 according to the method of step 4;

8. according to the method in the step 4, the washing liquid is injected to the reaction cotton, the residual reagent R2 is flushed to the waste liquid cavity, and the blue floccule and the hemoglobin are remained on the reaction cotton;

9. when the transverse motor 2 starts to work, the transverse motor 2 drives the reagent kit body 26 to move towards the light shielding plate 39, and when the transverse motor 2 drives the reagent kit body 26 to move to a set position, the opening of the detection cavity 34 is attached to and shielded by the light shielding plate 39, and the analysis hole 345 faces the light guide hole 40;

10. the detector 44 starts to work, and the detector 44 detects and displays the concentration value of the glycated hemoglobin;

11. the transverse motor 2 starts to work, the transverse motor 2 drives the reagent kit body 26 to move in the direction away from the light shielding plate 39, when the transverse motor 2 drives the reagent kit body 26 to move to a set position, the liquid-transferring gun 27 is positioned right above the gun head sleeve 45 at the moment, the transverse motor 2 stops working, the longitudinal motor 12 starts to work, the longitudinal motor 12 drives the liquid-transferring gun 27 to move downwards to a set distance, and the liquid-transferring gun 27 is inserted into the gun head sleeve 45 at the moment;

12. the gun withdrawing motor 18 starts to work, the gun withdrawing motor 18 drives the push plate 20 to move downwards, when the gun withdrawing motor 18 drives the push plate 20 to move downwards to a set distance, the push plate 20 pushes the liquid-transferring gun 27 to be separated from the air guide inserted rod 41 and inserted into the gun head sleeve, the gun withdrawing motor 18 continues to work, and the push plate 20 returns to the initial position;

13. the longitudinal motor 12 and the transverse motor 2 start to work, the transverse motor 2 drives the reagent box body 26 to return to the initial position, and the longitudinal motor 12 drives the air guide insertion rod 41 to return to the initial position to wait for the next round of test.

Claims (10)

1. The utility model provides a full automatization glycated haemoglobin detection device which characterized in that: the kit comprises a reagent kit seat and a reagent kit, the reagent kit comprises a reagent kit body and a liquid transferring gun, the liquid transferring gun is placed on the reagent kit body, the reagent kit body is installed on the reagent kit seat, the reagent kit seat is installed on a moving part of the transverse moving mechanism, the reagent kit body can reciprocate in the horizontal direction, a fixing part of the longitudinal moving mechanism is installed on a fixing part of the transverse moving mechanism, a fixing part of the gun returning mechanism is installed on a moving part of the longitudinal moving part, the gun returning mechanism can reciprocate in the vertical direction, the liquid transferring mechanism comprises a pressure pump, an air pipe and an air guide inserted bar inserted with the liquid transferring gun, the air guide inserted bar is fixed on the fixing part of the gun returning mechanism, the air guide inserted bar movably penetrates through the moving part of the gun returning mechanism, the moving part of the gun returning mechanism can reciprocate in the vertical direction, the air guide inserted bar is hollow, and two ends of the air pipe are respectively connected with the pressure pump and the air guide inserted bar;

when the kit body is located the initial position, the air guide inserted bar is located the kit body directly over, and when the kit body removed to the detection position, detection mechanism can detect the glycated haemoglobin in the kit body.

2. The fully automated glycated hemoglobin measurement apparatus according to claim 1, wherein: the horizontal moving mechanism comprises a supporting base plate, a horizontal motor support, a horizontal driving pulley, a horizontal driven pulley, a horizontal pulley shaft and a horizontal belt, the horizontal motor is installed on the supporting base plate through the horizontal motor support, the horizontal driving pulley is installed on the output end of the horizontal motor, the lower end of the horizontal pulley shaft is installed on the supporting base plate, the horizontal pulley shaft is perpendicular to the supporting base plate, the horizontal driven pulley is sleeved on the horizontal pulley shaft, the horizontal driving pulley is connected with the horizontal driven pulley through the horizontal belt, and the reagent box seat is fixed on the horizontal belt.

3. The apparatus for testing fully automated glycated hemoglobin according to claim 2, wherein: the transverse moving mechanism further comprises a transverse guide rail, a transverse sliding block and a transverse zero-returning sensor used for sensing that the reagent box body reaches an initial position, the transverse guide rail is installed on the supporting base plate and is parallel to the moving direction of the transverse belt, the transverse sliding block is installed on the transverse guide rail, the reagent box seat is fixed on the transverse sliding block, and the transverse zero-returning sensor is fixed on the supporting base plate.

4. The fully automated glycated hemoglobin measurement apparatus according to claim 1, wherein: the reagent box seat is provided with a slot matched with the reagent box body, and the reagent box body is spliced with the reagent box seat through the slot.

5. The fully automated glycated hemoglobin measurement apparatus according to claim 1, wherein: the longitudinal moving mechanism comprises a longitudinal supporting plate, a longitudinal motor, a longitudinal driving belt wheel, a longitudinal driven belt wheel, a longitudinal belt wheel shaft, a longitudinal belt, a longitudinal guide rail, a longitudinal sliding block and a longitudinal zero-returning sensor used for returning the connecting plate to the initial position, wherein the bottom of the longitudinal supporting plate is fixed on the supporting base plate, the longitudinal supporting plate is perpendicular to the supporting base plate, the longitudinal motor is installed at the bottom of the longitudinal supporting plate, one end of the longitudinal belt wheel shaft is installed at the top of the longitudinal supporting plate, the longitudinal belt wheel shaft is perpendicular to the longitudinal supporting plate, the longitudinal driving belt wheel is sleeved on an output shaft of the longitudinal motor, the longitudinal driven belt wheel is sleeved on the longitudinal belt wheel shaft, the longitudinal driving belt wheel is connected with the longitudinal driven belt wheel through the longitudinal belt, the longitudinal guide rail is installed on the longitudinal supporting plate, the longitudinal guide rail is parallel to the moving direction of the longitudinal belt, and the longitudinal sliding block is installed on the longitudinal guide rail.

6. The apparatus for testing fully automated glycated hemoglobin according to claim 5, wherein: move back rifle mechanism include the linkage plate, move back the rifle motor, move back rifle motor support, the push pedal and move back the rifle lead screw, the linkage plate is the U type, the vertical setting of linkage plate, linkage plate middle part and vertical slider are connected, the opening of linkage plate is vertical backup pad dorsad, move back rifle motor support respectively with the both sides edge fixed connection of linkage plate, vertical belt runs through the space that moves back rifle motor support and linkage plate enclose, and vertical belt is connected with the both sides part of linkage plate respectively, move back the rifle motor and install on moving back rifle motor support, move back the rifle lead screw including moving back the rifle screw rod and moving back the rifle nut, move back the upper end of rifle screw rod and be connected with the output that moves back the rifle motor, move back the rifle nut cover and locate on moving back the rifle lead screw, the push pedal horizontal cover is located on moving back the rifle nut, the air guide inserted bar runs through the push pedal, and air guide inserted bar and push pedal clearance fit, the force pump is the plunger pump.

7. The apparatus for testing fully automated glycated hemoglobin according to claim 6, wherein: move back rifle mechanism still include the deflector, the deflector level sets up, the deflector is fixed in moves back on the rifle motor support, the last pot head of air guide inserted bar is equipped with the mounting disc, the air guide inserted bar runs through the deflector, the air guide inserted bar passes through mounting disc and deflector fixed connection, is equipped with the guiding hole on the deflector, moves back rifle lead screw and guiding hole clearance fit.

8. The fully automated glycated hemoglobin measurement apparatus according to claim 1, wherein: the kit body on be equipped with along sharp sample hybrid chamber that distributes, rifle head chamber, first reagent chamber, second reagent chamber, wash liquor chamber and detection chamber, the sample hybrid chamber, the rifle head chamber, first reagent chamber, second reagent chamber, wash liquor chamber and detection chamber are isolated each other, the kit still includes the sampler of cavity form, the sampler comprises handle portion and flowing back portion, handle portion is the form of expanding, the flowing back portion is the toper, the symmetry is equipped with a pair of first drainage hole on the middle part of flowing back portion, be equipped with the second outage on the tip of flowing back portion, the flowing back portion is located the sample hybrid chamber, the opening of sealed sample hybrid chamber is blocked to the main aspects of flowing back portion, handle portion and the main aspects port intercommunication of flowing back portion, the liquid-transfering gun is accomodate in rifle head chamber, be equipped with in the detection intracavity and place the baffle analysis chamber and waste liquid waste chamber, it is equipped with the filtration hole to place baffle central authorities, analysis chamber covers on the opening and has closed the gland, the analysis hole is equipped with the analysis hole in the gland central authorities, the axis of filtration hole is the same with the analysis hole.

9. The apparatus for testing fully automated glycated hemoglobin according to claim 8, wherein: the kit body be squarely, and the kit body is the platykurtic, the sample hybrid chamber, the rifle head chamber, first reagent chamber, the second reagent chamber, wash the liquid chamber and detect the chamber and distribute along the length direction of kit body in proper order, and the rifle head chamber, first reagent chamber, the second reagent chamber, the opening in wash liquid chamber and detection chamber all is located a surface of kit body, the joint has hollow rifle head cover on the rifle head chamber, the pipetting gun runs through the rifle head cover, and pipetting gun and rifle head cover joint, be equipped with on the opposite side of kit body and be platelike handle, the handle is close to the sample hybrid chamber, and handle and sample hybrid chamber opening distribute on same straight line.

10. The fully automated glycated hemoglobin measurement apparatus according to claim 1, wherein: the detection mechanism including detecting regulation support, light screen, detector, detect the support including supporting the regulation riser and supporting the regulation diaphragm, support on the regulation riser is fixed in the supporting baseplate, support and be equipped with a plurality of regulation holes along vertical direction on the regulation riser, a plurality of regulation holes distribute along the straight line, be equipped with rectangular hole on one side of supporting the regulation diaphragm, support the regulation diaphragm and pass through fastening bolt and support and adjust the riser and be connected, the light screen is fixed in and supports on the bottom of adjusting the diaphragm opposite side, and the light screen perpendicular to supports the regulation diaphragm, the detector is fixed in on the light screen.

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