CN218332145U - Automatic slide scanner - Google Patents
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- CN218332145U CN218332145U CN202222989948.7U CN202222989948U CN218332145U CN 218332145 U CN218332145 U CN 218332145U CN 202222989948 U CN202222989948 U CN 202222989948U CN 218332145 U CN218332145 U CN 218332145U
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Abstract
The utility model relates to an automatic slide scanner, including image acquisition device and slide bearing device, slide bearing device is located image acquisition device top, and relative under operating condition image acquisition device moves along X/Y/Z axle direction and calibrates, image acquisition device includes image acquisition camera, fluorescence light source module and camera lens module, fluorescence light source module is equipped with the first mounting hole that is used for with image acquisition camera adaptation and is used for with the second mounting hole of camera lens module adaptation, fluorescence light source module includes at least two sets of fluorescence excitation subassembly, at least two sets of fluorescence excitation subassembly movably install in fluorescence light source module in order to carry out the light source and switch; the automatic slide scanner can be used for loading a plurality of groups of different fluorescent light sources, meets the requirement of flexibly switching the light sources under the working state, realizes automatic calibration, is flexible to use and can meet the use requirement.
Description
Technical Field
The utility model relates to a scanner technical field especially relates to an automatic slide scanner.
Background
At present, the slide observation is roughly divided into two modes: 1) The user can make a visual diagnosis through a traditional microscope; the microscope structure comprises a microscope bracket, an ocular lens, an objective lens, an optical connecting piece, an objective table, a coarse focusing screw, a fine focusing screw, a condensing lens and other parts, a user checks the slide for diagnosis by manually moving the slice under the ocular lens of a common microscope, the suspicious region is searched in time in the diagnosis process, and the digital storage of the image of the slide cannot be realized; 2) Firstly, digitizing the slide by adopting a digital slide scanner; then, the user diagnoses the digitized image at the computer terminal, the digitized image can be conveniently stored, remotely transmitted and the like, and various applications can be developed based on the digitized image. However, the slide scanner used in the second method still has the problems of not being able to be automatically calibrated and having difficulty in meeting the requirements of different scenes using a single light source.
SUMMERY OF THE UTILITY MODEL
In order to solve the problem, the utility model provides an automatic slide scanner, it can load the different fluorescence light source of multiunit, satisfies nimble switching light source under operating condition, realizes automatic calibration, uses in a flexible way, can satisfy the user demand.
The utility model adopts the technical proposal that:
an automatic slide scanner comprises an image acquisition device and a slide bearing device, wherein the slide bearing device is positioned above the image acquisition device and moves along the X/Y/Z axis direction relative to the image acquisition device in a working state to calibrate, the image acquisition device comprises an image acquisition camera, a fluorescent light source module and a lens module, the fluorescent light source module is provided with a first mounting hole matched with the image acquisition camera and a second mounting hole matched with the lens module, the fluorescent light source module comprises at least two groups of fluorescent excitation components, and the at least two groups of fluorescent excitation components are movably arranged in the fluorescent light source module to switch a light source.
In a further improvement of the above solution, the automatic slide scanner further comprises an X-axis transmission module, a Y-axis transmission module, and a Z-axis transmission module, wherein the X-axis transmission module, the Y-axis transmission module, and the Z-axis transmission module are respectively connected to the slide bearing device to drive the slide bearing device to move along the X/Y/Z axis direction relative to the image acquisition device in a working state.
In a further improvement of the above scheme, the slide bearing device includes a bearing table, a first sliding table and a second sliding table, the bearing table moves along the Z-axis direction relative to the image acquisition device, the first sliding table is connected with the bearing table in a sliding manner, the first sliding table moves along the X-axis direction relative to the bearing table, the second sliding table is connected with the first sliding table in a sliding manner, the second sliding table moves along the Y-axis direction relative to the first sliding table, and the second sliding table is provided with an observation area adapted to the slide.
The scheme is further improved in that the observation area is provided with a limiting groove for fixing the slide, and at least one hole groove for calibrating the lens module is formed around the limiting groove.
The automatic slide scanner further comprises an X-axis transmission module, a Y-axis transmission module and a Z-axis transmission module, wherein the X-axis transmission module, the Y-axis transmission module and the Z-axis transmission module are respectively connected with the image acquisition device so as to drive the image acquisition device to move along the X/Y/Z axis direction relative to the slide bearing device in a working state.
The fluorescent light source module further comprises a shell and a push-pull mechanism, wherein the inner side of the shell is connected with a slide rail structure, at least two groups of fluorescent excitation assemblies are sequentially arranged and are respectively connected with the slide rail structure, and the push-pull mechanism is connected with the slide rail structure to push the fluorescent excitation assemblies to move to switch light sources.
The slide rail structure comprises a slide rail and a slide block matched with the slide rail, the slide rail is arranged along the direction of the second mounting hole, and at least two groups of fluorescence excitation assemblies are sequentially arranged and fixed on the slide block.
The fluorescent light source module further comprises a shell and a driving assembly, wherein the inner side of the shell is connected with a turntable structure, at least two groups of fluorescent excitation assemblies are sequentially arranged and surround the turntable structure and are distributed and arranged, and the driving assembly is connected with the turntable structure to drive the turntable structure to rotate so as to switch the light source.
The further improvement of the scheme is that the turntable structure comprises a rotating part and a circular disc, the rotating part is arranged on the inner side of the shell, the circular disc is movably connected with the rotating part, and at least two groups of fluorescence excitation assemblies are arranged on the circular disc.
The further improvement of the above scheme is that the first mounting hole and the second mounting hole are respectively located at the upper side and the lower side of the fluorescent light source module, and the centers of the first mounting hole and the second mounting hole are located on the same vertical line.
The beneficial effects of the utility model are as follows:
the utility model discloses an automatic slide scanner is equipped with image acquisition device and slide and bears the device, and after the slide that will treat the observation was put into slide and is born the device, image acquisition device and slide bear the device and can move about relatively and carry out the position location, realize auto focus, automatic calibration and automatic scanning, use more in a flexible way. Meanwhile, the image acquisition device in the automatic slide scanner is provided with an image acquisition camera, a fluorescent light source module and a lens module, wherein the image acquisition camera is arranged at the position of a first mounting hole of the fluorescent light source module, the lens module is arranged at the position of a second mounting hole of the fluorescent light source module, a fluorescent light source of the fluorescent light source module acts on a slide to be observed through the lens module and the second mounting hole, and an image of the slide to be observed is acquired and stored by the image acquisition camera through the lens module, the second mounting hole, the fluorescent light source module and the first mounting hole, so that automatic image acquisition is realized; and at least two groups of fluorescence excitation components are arranged in the fluorescence light source module, the at least two groups of fluorescence excitation components are movably arranged in the fluorescence light source module, and the corresponding fluorescence excitation components are moved to the position of the second mounting hole in a manual or automatic mode, so that the switching of different fluorescence light sources is completed, the use is flexible, and the use requirements of different scenes can be met.
Drawings
Fig. 1 is a schematic perspective view of a first embodiment of the present invention;
fig. 2 is a schematic right-view structural diagram of a first embodiment of the present invention;
fig. 3 is a schematic structural diagram of a fluorescent light source module according to a first embodiment of the present invention;
fig. 4 is a schematic structural diagram of another view angle of the fluorescent light source module according to the first embodiment of the present invention;
fig. 5 is a schematic perspective view of a second embodiment of the present invention;
FIG. 6 isbase:Sub>A schematic sectional view A-A of FIG. 5.
Description of reference numerals: the device comprises an image acquisition device 100, an image acquisition camera 110, a fluorescent light source module 120, a fluorescent excitation assembly 121, a shell 122, a push-pull mechanism 123, a sliding rail structure 124, a sliding rail 125, a sliding block 126, a driving assembly 127, a turntable structure 128, a disc 129, a lens module 130, a slide carrying device 200, a carrying table 210, a first sliding table 220, a second sliding table 230, an observation area 231, a limiting groove 232, a hole groove 233, an X-axis transmission module 300, a Y-axis transmission module 400 and a Z-axis transmission module 500.
Detailed Description
The technical solution of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", "front", "rear", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected" and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; may be mechanically coupled, may be directly coupled, or may be indirectly coupled through an intermediary. The specific meaning of the above terms in the present invention can be understood as a specific case by those skilled in the art.
The first embodiment is as follows:
as shown in fig. 1-4, the utility model provides an automatic slide scanner, including image acquisition device 100 and slide bearing device 200, slide bearing device 200 is located image acquisition device 100 top, and relative image acquisition device 100 moves along the X/Y/Z axle direction and calibrates under operating condition, image acquisition device 100 includes image acquisition camera 110, fluorescence light source module 120 and camera lens module 130, fluorescence light source module 120 is equipped with the first mounting hole that is used for with image acquisition camera 110 adaptation and is used for the second mounting hole with camera lens module 130 adaptation, fluorescence light source module 120 includes at least two sets of fluorescence excitation subassembly 121, at least two sets of fluorescence excitation subassembly 121 movably install in fluorescence light source module 120 in order to carry out the light source and switch.
Therefore, the automatic slide scanner of the first embodiment is provided with the image acquisition device 100 and the slide bearing device 200, after a slide to be observed is placed in the slide bearing device 200, the image acquisition device 100 and the slide bearing device 200 can move up and down and left and right relatively to perform position positioning, so that automatic focusing, automatic calibration and automatic scanning are realized, and the use is more flexible. Meanwhile, the image acquisition device 100 in the automatic slide scanner is provided with an image acquisition camera 110, a fluorescent light source module 120 and a lens module 130, the image acquisition camera 110 is arranged in a first mounting hole of the fluorescent light source module 120, the lens module 130 is arranged in a second mounting hole of the fluorescent light source module 120, a fluorescent light source of the fluorescent light source module 120 acts on a slide to be observed through the lens module 130 and the second mounting hole, an image of the slide to be observed is acquired and stored by the image acquisition camera 110 through the lens module 130, the second mounting hole, the fluorescent light source module 120 and the first mounting hole, and automatic image acquisition is realized; and at least two sets of fluorescence excitation components 121 are arranged in the fluorescence light source module 120, at least two sets of fluorescence excitation components 121 can be movably arranged in the fluorescence light source module 120, and the corresponding relative positions of the fluorescence excitation components 121 are manually or automatically moved, so that the fluorescence excitation components 121 can be switched corresponding to the second mounting holes, and the fluorescence light source module is flexible to use and can meet the use requirements of different scenes.
As shown in fig. 1 and 2, the automatic slide scanner of the first embodiment further includes an X-axis transmission module 300, a Y-axis transmission module 400 and a Z-axis transmission module 500, wherein the X-axis transmission module 300, the Y-axis transmission module 400 and the Z-axis transmission module 500 are respectively connected to the slide bearing device 200 to drive the slide bearing device 200 to move along the X/Y/Z axis direction relative to the image capturing device 100 in the working state; therefore, in the first embodiment, the X-axis transmission module 300, the Y-axis transmission module 400 and the Z-axis transmission module 500 are disposed on the slide bearing device 200, and in the automatic calibration and automatic scanning processes, the slide bearing device 200 can move up and down and left and right relative to the image acquisition device 100, so as to realize stable movement, and further improve the image acquisition stability.
As shown in fig. 1 and 2, the slide bearing device 200 includes a carrier stage 210, a first slide stage 220, and a second slide stage 230, the carrier stage 210 moves in the Z-axis direction with respect to the image pickup device 100, the first slide stage 220 is slidably coupled to the carrier stage 210, and the first slide stage 220 moves in the X-axis direction with respect to the carrier stage 210, the second slide stage 230 is slidably coupled to the first slide stage 220, and the second slide stage 230 moves in the Y-axis direction with respect to the first slide stage 220, and the second slide stage 230 is provided with an observation area 231 for fitting to the slide. The observation area 231 is provided with a limiting groove 232 for fixing a slide, and at least one hole groove 233 for calibrating the lens module 130 is arranged around the limiting groove 232; thus, the movement in the X/Y/Z axis direction is realized by the linkage of the stage 210, the first slide stage 220, and the second slide stage 230. That is, the plummer 210 is connected with the Z-axis transmission module 500, the first sliding table 220 is connected with the X-axis transmission module 300, the second sliding table 230 is connected with the Y-axis transmission module 400, the X-axis transmission module 300 and the Y-axis transmission module 400 of the first embodiment can adopt high-precision stepping motors, the moving precision is higher, and the precision of collecting images in the automatic scanning process is higher.
As shown in fig. 1, 3 and 4, the fluorescent light source module 120 further includes a housing 122 and a push-pull mechanism 123, the inner side of the housing 122 is connected with a slide rail 125 structure 124, at least two groups of fluorescent excitation assemblies 121 are sequentially arranged and respectively connected with the slide rail 125 structure 124, and the push-pull mechanism 123 is connected with the slide rail 125 structure 124 to push the fluorescent excitation assemblies 121 to move for switching light sources; the sliding rail 125 structure 124 comprises a sliding rail 125 and a sliding block 126 matched with the sliding rail 125, the sliding rail 125 is arranged along the direction of the second mounting hole, and at least two groups of fluorescence excitation assemblies 121 are sequentially arranged and fixed on the sliding block 126; the fluorescence excitation assembly 121 in the first embodiment of the present invention can excite a fluorescence light source emitting one wavelength, the push-pull mechanism 123 can be set to be manual or automatic, when the fluorescence light source needs to be switched, the slide block 126 is pushed by the push-pull mechanism 123, and since the multiple sets of fluorescence excitation assemblies 121 are arranged and loaded on the slide block 126, the multiple sets of fluorescence excitation assemblies 121 on the slide block 126 also move along the direction of the slide rail 125, so that the fluorescence excitation assembly 121 needing to be switched corresponds to the position of the second mounting hole, that is, the switching of the light source is realized.
As shown in fig. 3 and 4, the first mounting hole and the second mounting hole are respectively located at the upper side and the lower side of the fluorescent light source module 120, and the centers of the first mounting hole and the second mounting hole are located on the same vertical line, which is beneficial for the image capturing camera 110 to capture images.
The second embodiment:
as shown in fig. 5 and 6, the utility model provides a another kind of automatic slide scanner, including image acquisition device 100 and slide bearing device 200, slide bearing device 200 is located image acquisition device 100 top, and relative image acquisition device 100 moves along the X/Y/Z axle direction and calibrates under operating condition, image acquisition device 100 includes image acquisition camera 110, fluorescence light source module 120 and lens module 130, fluorescence light source module 120 is equipped with the first mounting hole that is used for with image acquisition camera 110 adaptation and is used for the second mounting hole with lens module 130 adaptation, fluorescence light source module 120 includes at least two sets of fluorescence excitation subassembly 121, at least two sets of fluorescence excitation subassembly 121 movably are installed in fluorescence light source module 120 in order to carry out the light source switching.
Similarly, the second embodiment of the automatic slide scanner is provided with the image collecting device 100 and the slide bearing device 200, and after a slide to be observed is placed in the slide bearing device 200, the image collecting device 100 and the slide bearing device 200 can move up and down and left and right relatively to perform position positioning, so that automatic focusing, automatic calibration and automatic scanning are realized, and the use is more flexible. Meanwhile, the image acquisition device 100 in the automatic slide scanner is provided with an image acquisition camera 110, a fluorescent light source module 120 and a lens module 130, the image acquisition camera 110 is arranged in a first mounting hole of the fluorescent light source module 120, the lens module 130 is arranged in a second mounting hole of the fluorescent light source module 120, a fluorescent light source of the fluorescent light source module 120 acts on a slide to be observed through the lens module 130 and the second mounting hole, an image of the slide to be observed is acquired and stored by the image acquisition camera 110 through the lens module 130, the second mounting hole, the fluorescent light source module 120 and the first mounting hole, and automatic image acquisition is realized; and at least two sets of fluorescence excitation components 121 are arranged in the fluorescence light source module 120, at least two sets of fluorescence excitation components 121 can be movably arranged in the fluorescence light source module 120, and the corresponding relative positions of the fluorescence excitation components 121 are manually or automatically moved, so that the fluorescence excitation components 121 can be switched corresponding to the second mounting holes, and the fluorescence light source module is flexible to use and can meet the use requirements of different scenes.
The difference from the first embodiment is that the automatic slide scanner of the second embodiment includes an X-axis transmission module 300, a Y-axis transmission module 400 and a Z-axis transmission module 500, wherein the X-axis transmission module 300, the Y-axis transmission module 400 and the Z-axis transmission module 500 are respectively connected to the image capturing device 100 to drive the image capturing device 100 to move along the X/Y/Z axis direction relative to the slide carrying device 200 in the working state; therefore, the X-axis transmission module 300, the Y-axis transmission module 400 and the Z-axis transmission module 500 of the second embodiment are disposed on the image capturing device 100, and the image capturing device 100 moves up and down and left and right to achieve automatic calibration and automatic scanning.
In addition, the light source switching in the second embodiment adopts the turntable structure 128 to perform rotary switching. As shown in fig. 6, the fluorescent light source module 120 in the second embodiment includes a housing 122 and a driving assembly 127, the inside of the housing 122 is connected to a turntable structure 128, at least two groups of fluorescent excitation assemblies 121 are sequentially arranged and distributed around the turntable structure 128, and the driving assembly 127 is connected to the turntable structure 128 to drive the turntable structure 128 to rotate for switching light sources; the second embodiment of the turntable structure 128 includes a rotating member and a circular disc 129, the rotating member is disposed inside the housing 122, the circular disc 129 is movably connected to the rotating member, and at least two sets of fluorescence excitation components 121 are disposed on the circular disc 129. The fluorescence excitation assembly 121 of the second embodiment can excite and emit a fluorescence light source with one wavelength, the driving assembly 127 can be set to be automatic, when the light source needs to be switched, the driving assembly 127 drives the rotating piece to rotate, the disc 129 rotates along with the rotating piece and drives the fluorescence excitation assembly 121 to rotate, the fluorescence excitation assembly 121 to be switched is made to rotate to the position of the second mounting hole, the light source switching is achieved, the use is simple, and the use requirements of different scenes can be met.
The above-mentioned embodiments only represent several embodiments of the present invention, and the description thereof is more specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.
Claims (10)
1. The automatic slide scanner is characterized by comprising an image acquisition device and a slide bearing device, wherein the slide bearing device is positioned above the image acquisition device and moves relative to the image acquisition device in the X/Y/Z axis direction under the working state to calibrate, the image acquisition device comprises an image acquisition camera, a fluorescent light source module and a lens module, the fluorescent light source module is provided with a first mounting hole matched with the image acquisition camera and a second mounting hole matched with the lens module, the fluorescent light source module comprises at least two groups of fluorescent excitation components, and at least two groups of fluorescent excitation components are movably arranged in the fluorescent light source module to switch light sources.
2. The automated slide scanner of claim 1, further comprising an X-axis drive module, a Y-axis drive module, and a Z-axis drive module, wherein the X-axis drive module, the Y-axis drive module, and the Z-axis drive module are respectively coupled to the slide support device to drive the slide support device to move in an X/Y/Z direction relative to the image capture device in an operational state.
3. The automated slide scanner of claim 1 or 2, wherein the slide support device comprises a stage, a first slide stage and a second slide stage, the stage moves in a Z-axis direction relative to the image capture device, the first slide stage is slidably coupled to the stage and the first slide stage moves in an X-axis direction relative to the stage, the second slide stage is slidably coupled to the first slide stage and the second slide stage moves in a Y-axis direction relative to the first slide stage, the second slide stage is provided with an observation area for fitting to a slide.
4. The automated slide scanner of claim 3, wherein the viewing area has a retaining groove for securing a slide, the retaining groove having at least one aperture slot disposed therearound for alignment with the lens module.
5. The automated slide scanner of claim 1, further comprising an X-axis drive module, a Y-axis drive module, and a Z-axis drive module, wherein the X-axis drive module, the Y-axis drive module, and the Z-axis drive module are respectively coupled to the image capture device to drive the image capture device to move in an X/Y/Z direction relative to the slide support device in an operational state.
6. The automated slide scanner of claim 1, wherein the fluorescence light source module further comprises a housing and a push-pull mechanism, the inside of the housing is connected with a slide rail structure, at least two groups of the fluorescence excitation assemblies are sequentially arranged and respectively connected with the slide rail structure, and the push-pull mechanism is connected with the slide rail structure to push the fluorescence excitation assemblies to move for switching the light source.
7. The automated slide scanner of claim 6, wherein the slide rail structure includes a slide rail and a slider engaged with the slide rail, the slide rail is disposed along the second mounting hole, and at least two sets of the fluorescence excitation assemblies are sequentially fixed on the slider.
8. The automated slide scanner of claim 1, wherein the fluorescence light source module further comprises a housing and a driving assembly, a turntable structure is connected to an inner side of the housing, at least two groups of the fluorescence excitation assemblies are sequentially arranged and distributed around the turntable structure, and the driving assembly is connected to the turntable structure to drive the turntable structure to rotate for switching the light source.
9. The automated slide scanner of claim 8, wherein the turntable structure includes a rotatable member disposed inside the housing and a disk movably coupled to the rotatable member, at least two of the fluorescence excitation assemblies being disposed on the disk.
10. The automated slide scanner of claim 1, wherein the first mounting hole and the second mounting hole are located on upper and lower sides of the fluorescent light source module, respectively, and centers of the first mounting hole and the second mounting hole are located on a same vertical line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222989948.7U CN218332145U (en) | 2022-11-09 | 2022-11-09 | Automatic slide scanner |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222989948.7U CN218332145U (en) | 2022-11-09 | 2022-11-09 | Automatic slide scanner |
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| Publication Number | Publication Date |
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| CN218332145U true CN218332145U (en) | 2023-01-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202222989948.7U Active CN218332145U (en) | 2022-11-09 | 2022-11-09 | Automatic slide scanner |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117518445A (en) * | 2024-01-04 | 2024-02-06 | 江苏美克医学技术有限公司 | Microscope for vertically-arranged full-automatic slide reading |
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2022
- 2022-11-09 CN CN202222989948.7U patent/CN218332145U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117518445A (en) * | 2024-01-04 | 2024-02-06 | 江苏美克医学技术有限公司 | Microscope for vertically-arranged full-automatic slide reading |
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