CN218308019U

CN218308019U - Leading-in equipment of exosome transfer culture

Info

Publication number: CN218308019U
Application number: CN202222300564.XU
Authority: CN
Inventors: 张美娜; 李哲; 李金阳; 李�浩
Original assignee: Runmei Biotechnology Shenyang Co ltd
Current assignee: Runmei Biotechnology Shenyang Co ltd
Priority date: 2022-08-31
Filing date: 2022-08-31
Publication date: 2023-01-17
Anticipated expiration: 2032-08-31

Abstract

The utility model belongs to the technical field of burettes, in particular to a leading-in device for transferring and culturing exosomes, wherein a liquid storage cavity is integrally formed at the lower end of a liquid guide glass tube, a burette head is integrally formed at the lower part of the liquid storage cavity, a suction piece is arranged inside the liquid guide glass tube, and a heating piece is arranged outside the liquid storage cavity; the suction piece comprises a screw rod fixed by an output shaft of the miniature servo motor, an internal thread sleeve screwed outside the lower end of the screw rod, and a limiting block integrally formed at the lower end of the internal thread sleeve; through the suction piece that drainage glass intraduct set up to when being convenient for suction piece removed drainage glass intraduct, the liquid of stock solution intracavity portion passed through burette head business turn over, thereby be convenient for shift liquid, and then liquid is leading-in when cultivateing the exosome, and stock solution chamber integrated into one piece is at the lower extreme of drainage glass pipe simultaneously, and burette head integrated into one piece is in the lower part in stock solution chamber, and the liquid of being convenient for is in stock solution intracavity storage.

Description

Leading-in equipment of exosome transfer culture

Technical Field

The utility model belongs to the technical field of the burette, concretely relates to exosome shifts leading-in equipment of cultivateing.

Background

The dropper is used for sucking or adding a small amount of reagent, sucking supernatant liquid and separating out a precipitate, and the leading-in equipment for transferring and culturing the exosome usually adopts an electric dropper to transfer liquid and transfer the culture solution of the exosome.

Traditional electric dropper is not convenient for absorb more liquid when using to make electric dropper need shift liquid many times, and then consume the time of moving the liquid, move liquid poor stability simultaneously, the piston is not enough at the intraductal stability of removal of drain glass, is not convenient for carry out the problem of auxiliary heating to the burette simultaneously.

Therefore, a design is needed, more liquid can be stored during pipetting, the piston can move stably, and an electric dropper which is convenient for heating the liquid can be used for introducing the liquid into the secretion culture.

SUMMERY OF THE UTILITY MODEL

To solve the problems set forth in the background art described above. The utility model provides a leading-in equipment of exosome transfer culture.

In order to achieve the above purpose, the utility model provides the following technical scheme.

A leading-in device for exosome transfer culture comprises a liquid guide glass tube, a miniature servo motor, a press switch and a control screen, wherein the miniature servo motor is installed at the upper end of the liquid guide glass tube; the suction piece comprises a screw rod fixed by an output shaft of the miniature servo motor, an internal thread sleeve screwed outside the lower end of the screw rod, a limiting block integrally formed at the lower end of the internal thread sleeve, and a piston sleeved outside the limiting block and tightly attached to the inner surface of the liquid guide glass tube; the heating member includes the glass overcoat of the outside hot pressing welded in stock solution chamber, installs the ceramic radiation shield in the glass overcoat to and install the electric heating board in the ceramic radiation shield, and the outer surface contact in electric heating board and stock solution chamber.

As the utility model discloses a preferred technical scheme of leading-in equipment of exosome transfer culture, the casing of miniature servo motor lower extreme is fixed with the spacing lantern ring, and the inslot is seted up to spacing lantern ring internal surface and is installed the sealed ring of gluing, spacing lantern ring cover is in the upper end of drain glass pipe.

As the utility model discloses a preferred technical scheme of leading-in equipment of exosome transfer culture, the seal groove has been seted up to the surface of piston.

As the utility model discloses a preferred technical scheme of importing equipment of exosome transfer culture, stock solution chamber, glass overcoat, ceramic radiation shield and electric heating board are spherical structure.

As the utility model discloses a preferred technical scheme of leading-in equipment of exosome transfer culture, stopper and the inside internal thread intercommunication of internal thread sleeve pipe.

Compared with the prior art, the beneficial effects of the utility model are that: the suction piece is arranged inside the liquid guide glass tube, so that the suction piece can move in and out of the liquid guide glass tube conveniently, liquid inside the liquid storage cavity can enter and exit through the dropper head, the liquid can be transferred conveniently, and further the liquid can be guided into the secretion culture process, meanwhile, the liquid storage cavity is integrally formed at the lower end of the liquid guide glass tube, the dropper head is integrally formed at the lower part of the liquid storage cavity, the liquid can be stored in the liquid storage cavity conveniently, meanwhile, the heating piece is arranged outside the liquid storage cavity, the heating piece is used for heating the liquid inside the liquid storage cavity conveniently, the suction piece comprises a screw rod fixed by an output shaft of a micro servo motor, and an internal thread sleeve screwed outside the lower end of the screw rod, a limiting block at the lower end of the internal thread sleeve is integrally formed, a piston sleeved outside the limiting block is arranged, so that the screw rod can rotate inside the internal thread sleeve, the internal thread sleeve drives the piston to move inside the liquid guide glass tube through the limiting block, so that the liquid guide glass tube can suck under the action of the piston, a glass outer glass sleeve simultaneously, and a ceramic heat insulation sleeve arranged inside the ceramic heat insulation sleeve is arranged inside the ceramic heat insulation sleeve.

Drawings

The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention. In the drawings.

Fig. 1 is a schematic structural diagram of the present invention.

Fig. 2 is a schematic cross-sectional structure diagram of the present invention.

Fig. 3 is an enlarged schematic view of a portion a in fig. 2.

In the figure: 1. a liquid guiding glass tube; 2. a liquid storage cavity; 3. a dropper head; 4. a micro servo motor; 5. a limiting lantern ring; 6. sealing the rubber ring; 7. a screw rod; 8. a limiting block; 9. a piston; 10. an internally threaded sleeve; 11. pressing a switch; 12. a control screen; 13. a glass jacket; 14. a ceramic insulating sleeve; 15. an electrical heating plate; 16. and sealing grooves.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Examples are given.

Referring to fig. 1-3, the present invention provides a technical solution.

A leading-in device for exosome transfer culture comprises a liquid guide glass tube 1, a miniature servo motor 4 arranged at the upper end of the liquid guide glass tube 1, a push switch 11 and a control screen 12 arranged on the side surface of the miniature servo motor 4, a liquid storage cavity 2 is integrally formed at the lower end of the liquid guide glass tube 1, a dropper head 3 is integrally formed at the lower part of the liquid storage cavity 2, a suction piece is arranged inside the liquid guide glass tube 1, and a heating piece is arranged outside the liquid storage cavity 2; the suction piece comprises a screw rod 7 fixed on an output shaft of the micro servo motor 4, an internal thread sleeve 10 screwed outside the lower end of the screw rod 7, a limiting block 8 integrally formed at the lower end of the internal thread sleeve 10, and a piston 9 sleeved outside the limiting block 8, wherein the piston 9 is tightly attached to the inner surface of the liquid guide glass tube 1; the heating element comprises a glass outer sleeve 13 which is hot-pressed and welded outside the liquid storage cavity 2, a ceramic heat insulation sleeve 14 which is arranged in the glass outer sleeve 13, and an electric heating plate 15 which is arranged in the ceramic heat insulation sleeve 14, wherein the electric heating plate 15 is in contact with the outer surface of the liquid storage cavity 2.

In this embodiment, through the suction piece that the inside of drain glass pipe 1 set up, thereby when being convenient for suction piece moves inside drain glass pipe 1, the liquid in the inside of liquid storage chamber 2 passes in and out through dripper head 3, thereby be convenient for shift liquid, and then liquid is leading-in when cultivateing to the exosome, simultaneously liquid storage chamber 2 integrated into one piece is at the lower extreme of drain glass pipe 1, dripper head 3 integrated into one piece is in the lower part of liquid storage chamber 2, be convenient for liquid is stored in liquid storage chamber 2, simultaneously the heating member that the outside of liquid storage chamber 2 set up, be convenient for liquid heating of the inside of liquid storage chamber 2 of heating member, simultaneously suction piece includes lead screw 7 that miniature servo motor 4 output shaft is fixed, and the outside spiral internal thread sleeve 10 of lead screw 7 lower extreme, integrated into one piece is at stopper 8 of internal thread sleeve 10 lower extreme, the piston 9 of cover outside stopper 8, thereby when being convenient for lead screw 7 rotates in internal thread sleeve 10, internal thread sleeve 10 drives piston 9 through stopper 8 and moves inside drain glass pipe 1, thereby be convenient for drain glass pipe 1 to suck under the effect of piston 9, simultaneously including liquid storage chamber 2 outside glass heating member 13, and install the ceramic heat insulating sleeve 14 when ceramic heating plate 14 carries out the insulating against heat insulating heat when ceramic heating plate 14, the insulating sleeve 14 of ceramic outer cover of ceramic heating plate is convenient for insulating ceramic outer cover.

Specifically, a limiting sleeve ring 5 is fixed on a shell at the lower end of the miniature servo motor 4, a sealing rubber ring 6 is installed in a groove formed in the inner surface of the limiting sleeve ring 5, and the limiting sleeve ring 5 is sleeved at the upper end of the liquid guide glass tube 1.

Specifically, the outer surface of the piston 9 is provided with a sealing groove 16.

Specifically, the liquid storage cavity 2, the glass outer sleeve 13, the ceramic heat insulation sleeve 14 and the electric heating plate 15 are all of spherical structures.

Specifically, the internal threads inside the limiting block 8 and the internal thread sleeve 10 are communicated.

The utility model discloses a theory of operation and use flow: when the liquid guide glass tube is used, the end part of the dropper head 3 is inserted into liquid, the press switch 11 is pressed, the miniature servo motor 4 is connected with an external power supply through the press switch 11, the output shaft of the miniature servo motor 4 drives the screw rod 7 to rotate in the internal thread sleeve 10 at the moment, the internal thread sleeve 10 drives the limiting block 8 and the piston 9 to move in the liquid guide glass tube 1 at the same time, the space inside the liquid guide glass tube 1 is increased, the liquid enters the liquid storage cavity 2 from the dropper head 3 under the action of atmospheric pressure at the moment, and when the electric heating plate 15 is connected with the external power supply, the liquid storage cavity 2 is heated after the electric heating plate 15 generates heat.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing embodiments, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The utility model provides an leading-in equipment that exosome transfer was cultivateed, includes drain glass pipe (1) to and install miniature servo motor (4) in drain glass pipe (1) upper end, set up push switch (11) and control panel (12) at miniature servo motor (4) side surface, its characterized in that: a liquid storage cavity (2) is integrally formed at the lower end of the liquid guide glass tube (1), a dropper head (3) is integrally formed at the lower part of the liquid storage cavity (2), a suction piece is arranged inside the liquid guide glass tube (1), and a heating piece is arranged outside the liquid storage cavity (2);

the suction piece comprises a screw rod (7) fixed by an output shaft of the miniature servo motor (4), an internal thread sleeve (10) screwed outside the lower end of the screw rod (7), a limiting block (8) integrally formed at the lower end of the internal thread sleeve (10), and a piston (9) sleeved outside the limiting block (8), wherein the piston (9) is tightly attached to the inner surface of the liquid guide glass tube (1);

the heating element comprises a glass outer sleeve (13) which is hot-pressed and welded outside the liquid storage cavity (2), a ceramic heat insulation sleeve (14) which is arranged in the glass outer sleeve (13), and an electric heating plate (15) which is arranged in the ceramic heat insulation sleeve (14), wherein the electric heating plate (15) is in contact with the outer surface of the liquid storage cavity (2).

2. An introduction apparatus for exosome transfer culture according to claim 1, characterized in that: the shell at the lower end of the miniature servo motor (4) is fixed with a limiting sleeve ring (5), a sealing rubber ring (6) is installed in a groove formed in the inner surface of the limiting sleeve ring (5), and the limiting sleeve ring (5) is sleeved at the upper end of the liquid guide glass tube (1).

3. An introduction apparatus for exosome transfer culture according to claim 1, characterized in that: and a sealing groove (16) is formed in the outer surface of the piston (9).

4. An introduction apparatus for exosome transfer culture according to claim 1, characterized in that: the liquid storage cavity (2), the glass outer sleeve (13), the ceramic heat insulation sleeve (14) and the electric heating plate (15) are all of spherical structures.

5. An introduction apparatus for exosome transfer culture according to claim 1, characterized in that: the limiting block (8) is communicated with the internal thread inside the internal thread sleeve (10).