CN218262548U

CN218262548U - 3D cell culture device

Info

Publication number: CN218262548U
Application number: CN202222047634.5U
Authority: CN
Inventors: 邵子燊; 卢梦梦; 赖运浩
Original assignee: Guangzhou Huajin Pharmaceutical Technology Co ltd
Current assignee: Guangzhou Huajin Pharmaceutical Technology Co ltd
Priority date: 2022-08-04
Filing date: 2022-08-04
Publication date: 2023-01-10
Anticipated expiration: 2032-08-04

Abstract

The utility model relates to the technical field of cell culture, in particular to a 3D cell culture device, which comprises a bottom plate, wherein a placing mechanism is arranged on the bottom plate, the placing mechanism comprises a placing box, the top of the bottom plate is connected with the placing box in a clamping way, two ends of the placing box are provided with placing grooves, the cross section of each placing groove is of a fan-shaped structure, the tops of the two placing grooves extend to the outer side of the top of the placing box, the center of the top of the placing box is provided with a stand column, and the inner side of the bottom of the placing box is provided with a locking mechanism; can conveniently assemble, disassemble and hold the utensil for placing cells, and can not cause the cells to overflow in the swinging process.

Description

3D cell culture device

Technical Field

The utility model relates to a cell culture device specifically is a 3D cell culture device, belongs to cell culture technical field.

Background

Cell culture refers to a method for simulating in-vivo environment in vitro to enable the in-vivo environment to survive, grow, reproduce and maintain main structures and functions, most of the current cell culture devices commonly used in laboratories adopt culture media for culture, the culture media are static, cells are cultured in the static environment, and tissue fluid can flow in animal bodies, so that the traditional static cell culture devices are difficult to meet experiments.

Traditionally, the existing patent application numbers are: 202122384579.4 a 3D dynamic cell culture device, the cell that can be fine in the cultivation swings to can simulate the dynamic environment in the analog machine body and carry out dynamic cultivation to the cell, solve the phenomenon that present most cell culture devices all are static culture cell, however, the culture dish that this patent used is the rectangle structure, cause the cell to spill over easily at the swing in-process, and when follow-up getting the cell, inconvenient taking to the culture dish.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a 3D cell culture device just in order to solve above-mentioned problem, can make things convenient for the dismouting to hold to the utensil of placing the cell to can not cause the cell to spill over at the swing in-process.

The utility model discloses a following technical scheme realizes above-mentioned purpose, a 3D cell culture device, comprising a base plate, install placement mechanism on the bottom plate, placement mechanism is including placing the box, bottom plate top block is connected with places the box, it is equipped with the standing groove to place the box both ends, the standing groove cross section is fan-shaped structure, two the standing groove top extends to places the box top outside, place box top center department and install the stand, it installs blocked mechanical system to place box bottom inboard.

Preferably, the cross section of the bottom plate is of a concave structure, and the edge of the inner side of the top of the bottom plate is of an arc structure.

Preferably, the top of the upright post is provided with a pull buckle which is of a spherical structure, and the upright post is of a cross-shaped structure.

Preferably, a plurality of lugs are symmetrically installed respectively inside the two ends of the bottom plate, the lugs are in sliding connection with the inside of the bottom plate through abutting springs, one end of each lug is of a hemispherical structure, and one end of each lug extends to the inside of the bottom plate and abuts against the inner side of the side wall of the placing box.

Preferably, the locking mechanism comprises clamping plates, symmetrical clamping plates are installed on the inner side of the bottom of the placing box, the clamping plates are connected with the inside of the placing box in a sliding mode through reset springs, clamping grooves are formed in the inner sides of the two ends of the bottom plate, one ends of the clamping plates extend into the clamping grooves, a top rod is connected to the center of the inside of the placing box in a sliding mode, the bottom of the top rod is located between the two clamping plates, the bottom of the top rod and the other ends of the two clamping plates are of arc-shaped structures, the bottom of the stand column is connected with the placing box in a rotating mode, a lead screw is installed at the bottom of the stand column, and the bottom of the lead screw is connected with the inner threads of the top rod.

Preferably, a plurality of kicking blocks are installed to bottom plate bottom inboard, the kicking block passes through compression spring and the inside sliding connection of bottom plate, the kicking block top extends to the bottom plate inboard and places the conflict of box bottom.

The utility model has the advantages that: conveniently under the effect through the bottom to placing and the block, conveniently place box and bottom plate dismouting under the cooperation of blocked mechanical system to the block is firm stable, and be favorable to making things convenient for follow-up getting to put the cell of cultivateing, conveniently makes the cell culture place under the effect of placing box and standing groove, simultaneously through the fan-shaped design of standing groove cross section, can not cause the cell to spill over when being favorable to placing the box and following the bottom plate swing, makes things convenient for the cell to swing smoothly level and smooth and level in the standing groove inside simultaneously.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic view of the connection structure of the placing box and the bottom plate of the present invention;

FIG. 3 is an enlarged view of the part A shown in FIG. 2;

fig. 4 is an enlarged schematic view of a portion B shown in fig. 2.

In the figure: 1. a base plate; 2. a placement mechanism; 201. placing a box; 202. a placement groove; 203. a column; 204. pulling the button; 205. a bump; 206. against the spring; 3. a locking mechanism; 301. a screw rod; 302. a top rod; 303. clamping a plate; 304. a card slot; 305. a return spring; 306. a top block; 307. compressing the spring.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-4, a 3D cell culture apparatus includes a bottom plate 1, a placing mechanism 2 is installed on the bottom plate 1, the placing mechanism 2 includes a placing box 201, the top of the bottom plate 1 is connected with the placing box 201 in a clamping manner, placing grooves 202 are formed in two ends of the placing box 201, the cross section of each placing groove 202 is of a fan-shaped structure, the tops of the two placing grooves 202 extend to the outer side of the top of the placing box 201, an upright column 203 is installed in the center of the top of the placing box 201, and a locking mechanism 3 is installed on the inner side of the bottom of the placing box 201.

As a technical optimization scheme of the utility model, 1 cross section of bottom plate is "concave" font structure, the inboard edge in 1 top of bottom plate is the arc structure, is favorable to the convenience place box 201 bottom 1 inside block of bottom plate is placed to make things convenient for follow-up dismouting, it is more convenient to operate.

As the utility model discloses a technical optimization scheme, the stand 203 top is installed and is drawn knot 204, draw knot 204 to be the ball shape structure, stand 203 is "ten" font structure, through convenient right under the effect of stand 203 place box 201 and take, and it is right under the effect of knot 204 to draw stand 203 to take to stabilize and be difficult for the slippage.

As the utility model discloses a technical optimization scheme, a plurality of lugs 205 are installed to the inside symmetry respectively in 1 both ends of bottom plate, lug 205 is through conflict spring 206 and the inside sliding connection of bottom plate 1, lug 205 one end is the semi spherical structure, lug 205 one end extends to 1 inside and place the inboard conflict of box 201 lateral wall of bottom plate, through make under the effect of conflict spring 206 lug 205 has the elasticity, because lug 205 one end is the semi spherical structure, makes place box 201 block 1 inside back of bottom plate, lug 205 can be right place box 201 lateral wall and contradict, make place box 201 and be in 1 inside block of bottom plate is stable difficult for droing to it is right to make things convenient for follow-up pulling place box 201 and take out.

As a technical optimization scheme of the utility model, blocked mechanical system 3 includes cardboard 303, place the cardboard 303 that box 201 bottom inboard was installed the symmetry, cardboard 303 passes through reset spring 305 and places the inside sliding connection of

box

201, 1 both ends inboard of bottom plate is equipped with draw-in groove 304, two cardboard 303 one end extends to inside the draw-in groove 304, it has ejector pin 302 to place the inside center department sliding connection of box 201, ejector pin 302 bottom is located two between the cardboard 303, ejector pin 302 bottom and two cardboard 303 other ends are the arc structure, stand 203 bottom is rotated with placing box 201 and is connected, lead screw 301 is installed to stand 203 bottom, lead screw 301 bottom and the inside threaded connection of ejector pin 302, through right stand 203's rotation, make lead screw 301 drives ejector pin 302 gliding, ejector pin 302 is to two cardboard 303 conflicts, makes cardboard 303 extends to inside right place box 201 spacing, through the antiport, ejector pin 302 contracts, cardboard 303 is in reset spring 305's effect with draw-in groove 304 separation, it is convenient to place box 201 with bottom plate 1 can conveniently dismantle.

As a technical optimization scheme of the utility model, a plurality of kicking blocks 306 are installed to 1 bottom inboard of bottom plate, kicking block 306 passes through

compression spring

307 and 1 inside sliding connection of bottom plate, kicking block 306 top extends to 1 inboard of bottom plate and places box 201 bottom and contradicts, through it goes into to place box 201 card 1 inside back of bottom plate, kicking block 306 breaks away from shrink under compression spring 307's the effect, through it contacts spacing back to place box 201, kicking block 306 is in compression spring 307's effect is right down it is ejecting to place box 201, makes it conveniently easily takes out the dismantlement to place box 201.

The utility model discloses when using, at first draw knot 204 through rotating, make and draw knot 204 to drive stand 203 and rotate on placing box 201, and drive lead screw 301 is controlled ejector pin 302, thereby make cardboard 303 shrink and draw-in groove 304 separation under reset spring 305's effect, to placing box 201 jack-up under a plurality of kicking blocks 306 and compression spring 307's effect, lug 205 can be contradicted and break away from the shrink under the effect of conflict spring 206 simultaneously, convenient pulling draws knot 204 to make and places box 201 and take out from bottom plate 1 inside, thereby conveniently get the cell put, it is inboard to insert to place box 201 to bottom plate 1 top at last, make under the effect of lug 205 place box 201 and place stably, and place box 201 and break away from and put in place under the conflict of kicking block 306, finally rotate and draw knot 204, make ejector pin 302 contradict to two cardboard 303, cardboard 303 breaks away from under reset spring 305's the effect and draw-in groove 304 inside block, it is stable firm to make to place box and bottom plate 1, be favorable to follow-up swing work, realize better cultivation of cell 201.

It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.

Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims

1. A3D cell culture device comprising a base plate (1), characterized in that: install on bottom plate (1) and place mechanism (2), place mechanism (2) including placing box (201), bottom plate (1) top block is connected with places box (201), it is equipped with standing groove (202) to place box (201) both ends, standing groove (202) cross section is fan-shaped structure, two standing groove (202) top extends to places box (201) top outside, place box (201) top center department and install stand (203), it installs blocked mechanical system (3) to place box (201) bottom inboard.

2. A 3D cell culture apparatus according to claim 1, wherein: the cross section of the bottom plate (1) is of a concave structure, and the edge of the inner side of the top of the bottom plate (1) is of an arc structure.

3. A 3D cell culture apparatus according to claim 1, wherein: the top of the upright post (203) is provided with a pull button (204), the pull button (204) is of a spherical structure, and the upright post (203) is of a cross-shaped structure.

4. A 3D cell culture apparatus according to claim 1, wherein: a plurality of lugs (205) are installed to bottom plate (1) both ends inside symmetry respectively, lug (205) are through conflict spring (206) and the inside sliding connection of bottom plate (1), lug (205) one end is the hemisphere structure, lug (205) one end extends to bottom plate (1) inside and places box (201) lateral wall inboard conflict.

5. A 3D cell culture apparatus according to claim 1, wherein: blocked mechanical system (3) include cardboard (303), place cardboard (303) that box (201) bottom inboard is installed the symmetry, cardboard (303) through reset spring (305) with place the inside sliding connection of box (201), bottom plate (1) both ends inboard is equipped with draw-in groove (304), two cardboard (303) one end extends to inside draw-in groove (304), place box (201) inside center department sliding connection and have ejector pin (302), ejector pin (302) bottom is located two between cardboard (303), stand (203) bottom with place box (201) and rotate and be connected, lead screw (301) are installed to stand (203) bottom, lead screw (301) bottom and ejector pin (302) internal thread are connected.

6. A3D cell culture apparatus according to claim 5, wherein: the bottom of the ejector rod (302) and the other ends of the two clamping plates (303) are both arc-shaped structures, and the clamping plates (303) are in a cross-shaped structure.

7. A 3D cell culture apparatus according to claim 1, wherein: a plurality of kicking blocks (306) are installed to bottom plate (1) bottom inboard, kicking block (306) pass through compression spring (307) and bottom plate (1) inside sliding connection, kicking block (306) top extends to bottom plate (1) inboard and places box (201) bottom and contradicts.