CN218214665U - Lead can and transport container - Google Patents
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- CN218214665U CN218214665U CN202222451405.XU CN202222451405U CN218214665U CN 218214665 U CN218214665 U CN 218214665U CN 202222451405 U CN202222451405 U CN 202222451405U CN 218214665 U CN218214665 U CN 218214665U
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Abstract
A lead can and shipping container for the shipment of radiopharmaceuticals, the lead can comprising: the lead can comprises a lead can body, wherein an open accommodating groove is formed in the lead can body, and the accommodating groove comprises a first accommodating space and a second accommodating space which are sequentially far away from the bottom of the accommodating groove and are sequentially adjacent to each other; and the lead can cover body is provided with a groove, when the lead can cover body is buckled on the lead can body, the accommodating groove and the groove form an accommodating part, at least one part of the side wall of the lead can cover body is accommodated in the second accommodating space, and the maximum thickness of the side wall of the lead can body is smaller than that of the side wall of the lead can cover body.
Description
Technical Field
The disclosure relates to the technical field of medicines, in particular to a lead can and a transport container for transporting radiopharmaceuticals.
Background
Some radiopharmaceuticals contain radionuclides with a short half-life, consisting ofThis results in a short shelf life of the radiopharmaceutical, e.g., 177 the half-life of the Lu nuclide is only 6.64 days, 177 the effective period of the lutetium oxygen octreotide injection marked by the Lu nuclide is only 3 days. The radiopharmaceuticals are generally transported and delivered by air transportation, the transportation containers thereof need to meet the requirements of radioprotection and air transportation, the conventional radiopharmaceuticals have large volumes and heavy weights, and the manufacturing cost and the transportation cost of the transportation containers are high.
SUMMERY OF THE UTILITY MODEL
Some embodiments of the present disclosure provide a lead can for transport of a radiopharmaceutical, the lead can comprising:
the lead can comprises a lead can body, wherein an open accommodating groove is formed in the lead can body, and the accommodating groove comprises a first accommodating space and a second accommodating space which are sequentially far away from the bottom of the accommodating groove and are sequentially adjacent to each other; and
a lead can cover body, the lead can cover body is provided with a groove,
when the lead can cover body is buckled on the lead can body, the accommodating groove and the groove form an accommodating part, at least one part of the side wall of the lead can cover body is accommodated in the second accommodating space, and the maximum thickness of the side wall of the lead can body is smaller than that of the side wall of the lead can cover body.
In some embodiments, in the direction of the axis of the lead can body, the inner side wall of the second accommodating space gradually converges toward the axis of the lead can body as gradually approaching the first accommodating space,
the outer surface of the side wall of the lead can cover includes a first outer surface that gradually converges toward the axis of the lead can cover as it gradually moves away from the top surface of the lead can cover in the direction of the axis of the lead can cover,
when the lead can cover body is buckled on the lead can body, the first outer surface is matched and attached with the inner side wall of the second accommodating space, so that the axis of the lead can body is collinear with the axis of the lead can cover body.
In some embodiments, the intersection of the inner surface of the side wall of the lead can body and the first outer surface has a rounded corner.
In some embodiments, the inner surface of the side wall of the lead can cover body is parallel to the axis of the lead can cover body, the inner side wall of the first accommodating space is parallel to the axis of the lead can body,
when the lead can cover body is buckled on the lead can body, the inner surface of the side wall of the lead can cover body is closer to the axis of the lead can body relative to the inner side wall of the first accommodating space.
In some embodiments, the outer surface of the side wall of the lead can body further comprises a second outer surface and a third outer surface, the third outer surface being located between the second outer surface and the first outer surface,
when the lead can cover body is buckled on the lead can body, the second outer surface is coplanar with the outer side wall of the lead can body, and the third outer surface is matched and attached with the top surface of the side wall of the lead can body.
In some embodiments, the lead can is made of lead-antimony alloy, so that the lead can be manufactured by stamping.
In some embodiments, the exterior surface of the lead can is coated with a protective paint.
In some embodiments, the lead can is made of lead-antimony alloy.
Some embodiments of the present disclosure provide a transport container for a radiopharmaceutical including:
a vial configured to hold a radiopharmaceutical;
the lead can of the previous embodiment configured to receive the vial;
a liquid-absorbing sponge configured to wrap the lead can to absorb the leaked liquid;
a metal sealed can configured to receive the lead can wrapped by the wicking sponge;
a buffer protective layer configured to wrap the metal can; and
a corrugated box configured to accommodate the metal sealed can wrapped by the buffer protective layer,
the surface of the lead can containing the medicine bottle is subjected to thermoplastic sealing, so that the outer surface of the lead can is wrapped with a thermoplastic sealing film.
In some embodiments, the material of the metal sealed can is a corrosion resistant material.
Drawings
In order to clearly illustrate the embodiments or technical solutions of the present disclosure, the drawings used in the embodiments or technical solutions of the present disclosure will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present disclosure, and other drawings can be obtained by those skilled in the art without creative efforts.
Fig. 1 is a schematic illustration of an exploded structure of a transport container for a radiopharmaceutical provided in some embodiments of the present disclosure;
FIG. 2 is a schematic view of the lead can of FIG. 1 with a drug contained therein;
fig. 3 is a schematic cross-sectional view of the lead can of fig. 2, wherein the lead can accommodates a vial therein.
Detailed Description
To make the objects, technical solutions and advantages of the present disclosure more apparent, the present disclosure will be described in further detail with reference to the accompanying drawings, and it is apparent that the described embodiments are only some embodiments of the present disclosure, not all embodiments. All other embodiments, which can be derived by one of ordinary skill in the art from the embodiments disclosed herein without making any creative effort, shall fall within the scope of protection of the present disclosure.
The terminology used in the embodiments of the present disclosure is for the purpose of describing particular embodiments only and is not intended to be limiting of the disclosure. As used in the disclosed embodiments and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise, and "a plurality" typically includes at least two.
It should be understood that the term "and/or" as used herein is merely a relationship that describes an associated object, meaning that three relationships may exist, e.g., a and/or B, may represent: a exists alone, A and B exist simultaneously, and B exists alone. In addition, the character "/" herein generally indicates that the former and latter related objects are in an "or" relationship.
Alternative embodiments of the present disclosure are described in detail below with reference to the drawings.
Fig. 1 is a schematic diagram of an exploded structure of a transport container for a radiopharmaceutical provided in some embodiments of the present disclosure. Fig. 2 is a schematic structural view of the lead can of fig. 1, wherein the lead can contains a drug. Fig. 3 is a schematic cross-sectional view of the lead can of fig. 2, wherein the lead can contains a medicine bottle. Some embodiments of the present disclosure provide a radiopharmaceutical transport container, as shown in fig. 1-3, a radiopharmaceutical transport container 100 comprising: a medicine bottle 10, a lead can 20, a liquid absorbing sponge 30, a metal sealing can 40, a buffer protection layer 50 and a corrugated case 60.
The vial 10 is adapted to contain a radiopharmaceutical, such as lutetium [ lutetium ] 177 Lu]Oxoargitide injection is suitable for treating unresectable or metastatic adult, progressive, highly differentiated (G1 and G2) and somatostatin receptor positive gastrointestinal and pancreatic neuroendocrine tumors (GEP-NETs). Lutetium [ lutetium ] 177 Lu]The clinical research on the risk of disease progression of the oxooctreotide injection is reduced by 79 percent compared with the traditional therapy.
177 Lu has obvious advantages in the field of tumor treatment due to its excellent radiation physical properties. It has the following advantages when being used for clinical diagnosis and treatment:
(1) 177 lu beta rays have better energy deposition in small-volume tumors, while not emitting high-energy beta rays (76% beta decay (E) β (max) =0.497 MeV)) cause high side effects on surrounding healthy tissue;
(2) Low energy gamma rays (E) with beta ray emission γ =113keV (6.6%), 208keV (11%)) can be SPECT imaged, which is extremely advantageous in the new generation of radiopharmaceutical development strategy directed to "precision medicine", "personalized medicine", and "integrated therapy".
(3) In solution, lu exists in a +3 oxidation state and is easy to form coordination reaction with N and O, so that the Lu can be connected with a plurality of carriers through bifunctional ligands. Meanwhile, lu has no other stable valence, oxidation-reduction reaction is difficult to occur in the solution, the Lu can stably exist in +3 valence in various chemical environments, the Lu labeled drug with high purity and stable chemical properties can be obtained, and the Lu labeled drug can also be effectively prevented from being metabolized in vivo in the research process 177 Lu is off-target, causing side effects to other tissues.
(4) 177 Lu has a suitable half-life (6.64 days) and facilitates cumbersome procedures for radiolabelling, purification, quality control and transportation.
177 Lu toxicity is grouped as toxic radionuclides. The half-life period is about 6.64 days, and due to the decay characteristics, the decayed beta rays have the characteristics of low energy, short range and no radioactive aerosol, and can meet the relevant requirements in the radioactive product safety transportation regulations on radiation protection only by making radioactive shielding.
The medicine bottle 10 is, for example, a penicillin bottle, which is, for example, an injection bottle made of borosilicate glass, and includes a medicine bottle body and a rubber plug matched with the medicine bottle body, wherein the rubber plug is buckled on the medicine bottle body to seal the radiopharmaceutical in the containing medicine bottle body.
The lead can 20 is used for accommodating the medicine bottle 10, and is used for isolating the radiation of the radioactive medicine to avoid the pollution caused by radiation leakage.
A metal sealed can 40 houses the lead can wrapped by the wicking sponge. The metal sealing can is made of an anti-corrosion material such as tinplate, and has good sealing and anti-corrosion characteristics and low price. Even if the lead can and the medicine bottle contained therein are damaged, the metal sealing can 40 can seal the liquid absorption sponge absorbed with the radioactive liquid medicine to prevent pollution from leaking. In some embodiments, the shape and size of the interior space of the metal sealed can 40 matches the shape and size of the liquid-absorbent sponge 30. For example, as shown in fig. 1, the shape of the liquid absorbing sponge 30 is, for example, a cylindrical shape, and the inner space of the metal sealed can 40 is also a cylindrical shape. The size of the liquid absorbing sponge 30 is, for example, equal to or slightly larger than the size of the inner space of the metal sealing can 40, so that when the liquid absorbing sponge 30 wrapped with the lead can 20 is accommodated in the metal sealing can 40, the liquid absorbing sponge 30 wrapped with the lead can 20 can be prevented from shaking in the metal sealing can 40, and the lead can and the medicine bottle therein can be stabilized.
The buffer protection layer 50 is configured to wrap the metal sealing can 40, and plays a role of buffering, and is made of, for example, a pearl foam material. The buffer protection layer 50 includes a protection layer body 51 and a protection layer cover 52, wherein a third groove 511, for example, a non-through groove, is provided on the protection layer body 51, and a fourth groove 521, for example, a non-through groove, is provided on the protection layer cover 52, when the protection layer cover 52 is fastened on the protection layer body 51, the third groove 511 and the fourth groove 521 are aligned and spliced, and the two are spliced to form an accommodating groove for accommodating the metal sealing can 40. The receiving groove portion is matched in shape and size to the metal can 40, and substantially fittingly receives the metal can 40. For example, the metal can 40 is cylindrical, and the receiving groove is also called a cylindrical groove. For example, the size of the accommodating groove portion is equal to or slightly smaller than that of the metal sealing can 40, so that the metal sealing can 40 can be tightly wrapped by the buffer protection layer 50 when being placed in the accommodating groove portion of the buffer protection layer 50, and the metal sealing can 40 is prevented from shaking in the accommodating groove portion of the buffer protection layer 50. The buffer protection layer 50 also plays a role in stabilizing the lead can, and the elastic performance of the buffer protection layer 50 can also provide a buffer effect to prevent the metal seal can 40 from being damaged.
The corrugated box 60 is configured to accommodate the metal sealed can 40 wrapped by the buffer protective layer 50. The corrugated case 60, which is used as the outermost package of the transport container 100, has the advantages of light weight, good cushioning property, low price, easy recycling, etc. In some embodiments, the shape and size of the interior space of the corrugated box 60 matches the shape and size of the cushioning protective layer 50. As shown in fig. 1, the buffer protection layer 50 is, for example, square, and the interior space of the corrugated box 60 is also square. The size of the buffer protection layer 50 is, for example, equal to or slightly larger than the size of the inner space of the corrugated case 60, so that when the buffer protection layer 50 wrapped with the metal seal can 40 is accommodated in the corrugated case 60, the buffer protection layer 50 wrapped with the metal seal can 40 can be prevented from shaking in the corrugated case 60, and the metal seal can 40 can be stabilized. In some embodiments, the corrugated box 60 has a square shape, for example, with a side length of 25cm, for example, to facilitate loading and carrying.
In some embodiments, the surface of the lead can 20 after receiving the vial 10 is heat sealed such that the outer surface of the lead can 20 is wrapped by a thermoplastic sealing film. The process of dispensing a radiopharmaceutical into a vial and housing the vial in a lead can is typically performed in a radiation-resistant environment, such as a radiation-resistant box, where the outer surface of the lead can inevitably contaminates the vial with a small amount of radioactive contaminants. In order to avoid causing harm to operators in the subsequent transportation operation process, a thermoplastic sealing film is formed on the outer surface of the lead can by adopting a thermal plastic packaging process to the lead can containing the medicine bottle taken out from the radioactive environment, and the lead can 20 is hermetically wrapped to isolate radioactive contamination on the outer surface of the lead can.
In addition, adopt the thermoplastic seal membrane including lead tank 20, can make the lead tank body and the lead tank lid of lead tank seal together for both are difficult for separating, guarantee the leakproofness of lead tank in the transportation.
In the above embodiment, adopt cooperation lead can and medicine bottle such as corrugated box, imbibition sponge to constitute disposable transport container, under the condition that satisfies radioactivity protection requirement and air transportation requirement, reduce cost. The transportation container has small volume, thereby being beneficial to the safety of loading; the weight is light, thus being beneficial to air transportation; the packaging mode is simple, and the stable and reliable packaging quality can be ensured; the disposable transportation packaging material avoids the unsafe factors of the damage of the reusable transportation packaging in the using process to reuse.
In some embodiments, the protective thickness of the lead can is determined in the following manner.
The radiation protection shield calculation formula is as follows:
wherein:
representing the rate of kerma;
a represents the activity of the radioactive source;
Г k represents the air kerma constant (1.19X 10) -18 Gy·m 2 ·Bq -1 ·S -1 )；
r represents the distance from the outer surface of the transport container to the radioactive source, taking a cube with a side length of 25cm as an example,
r may be taken to be 0.125m.
Oxoargitide injection with 250mCi ( 177 Lu-DOTATATE) as an example
Due to the fact that
Wherein the content of the first and second substances,
represents the absorption dose rate;
wherein H represents an equivalent dose; radiation weight factor Q =1.
If the dose on the outer surface of the transport container is controlled at 0.005mSv/h, the attenuation times K =2.54/0.005=508, the radiation energy conservation is calculated according to 0.25MeV, the semivalent layer thickness of 0.88mm for 0.25MeV lead is calculated as lg2 (508) as 8.9887, and the lead shielding layer thickness is about 8mm by multiplying the semivalent layer thickness by 0.88 mm. At the same time, the lead can is then packaged in a secondary shipping package such that the shipping container is 10cm from the lead can, the dose rate at the surface of the bale will be well below 0.005mSv/h.
According to the above calculation, maximum 177 Lu activity is 250mCi, lead can thickness is designed to be 9mm, redundancy is increased, the lead can is placed in the center of the corrugated case, and the distance between the surface of the lead can and the surface of the transport container is 10cm (the distance between the surface of the transport container and the center of the radioactive source is 12.5 cm). The surface dose rate of the transport container was 0.16. Mu. Sv/h, calculated using Rad Pro calcelletor radiation protection calculation software. Is far lower than the regulation that H is more than 0.005mSv/H and less than or equal to 0.5mSv/H in the safety transportation regulations of radioactive products.
Referring to the construction of the lead can, as shown in fig. 2-3, the lead can 20 includes a lead can body 21 and a lead can cover 22.
The lead can comprises a lead can body 21, wherein an open accommodating groove 211 is formed in the lead can body, the accommodating groove 211 comprises a first accommodating space 2111 and a second accommodating space 2112 which are sequentially away from the bottom of the accommodating groove and are sequentially adjacent, and the accommodating groove 211 is configured to accommodate at least one part of the medicine bottle 10. The medicine bottle 10 includes, for example, a medicine bottle body 11 and a rubber stopper 12. The rubber plugs 12 are, for example, butyl rubber plugs. The rubber plug 12 can be buckled on the medicine bottle body 11 to realize the sealing of the medicine bottle 10. In some embodiments, the vial 10 may further include a packaging cap, such as an aluminum cap, that packages the plug onto the vial body 11. As shown in fig. 1 to 3, the neck portion of the vial body 11 and a portion above the neck portion are accommodated in the second accommodation space 2112, for example, and a portion below the neck portion of the vial body 11 is accommodated in the first accommodation space 2111, for example.
The lead can cover 22 has a groove 221, and when the lead can cover 22 is fastened to the lead can body 21, the accommodating groove 211 and the groove 221 form an accommodating portion for accommodating the medicine bottle 10 in a sealed manner, and at least a portion of the side wall of the lead can cover 22 is accommodated in the second accommodating space 2112. That is, a portion of the lead can cover 22 is inserted into the receiving groove 211, so that the lead can cover 22 is tightly fastened to the lead can body 21.
In some embodiments, as shown in fig. 2 to 3, in the direction of the axis m1 of the lead can body 21, the inner side wall of the second accommodating space 2112 gradually converges toward the axis m1 of the lead can body as gradually approaching the first accommodating space 2111. Facilitating the introduction of the vial 10 into the lead can body 21.
The outer surface 222 of the side wall of the lead can cover 22 includes a first outer surface 2221, and in the direction of the axis m2 of the lead can cover, the first outer surface 2221 gradually converges toward the axis m2 of the lead can cover as it gradually moves away from the top surface of the lead can cover. When the lead can cover 22 is fastened to the lead can body 21, the first outer surface 2221 is fitted to the inner side wall of the second accommodating space 2112, so that the axis m1 of the lead can body 21 is collinear with the axis m2 of the lead can cover 22. As shown in fig. 2 to 3, the cross section of the first outer surface 2221 is, for example, an inclined surface, the cross section of the inner sidewall of the second accommodating space 2112 is also an inclined surface, and the inclination of the two is the same, and the inclination range of the two is, for example, tg45 ° to tg70 °. By adopting the arrangement, when the lead can cover 22 is buckled on the lead can body 21, under the self-weight effect of the lead can cover 22, the lead can cover 22 can be buckled with the lead can body 21 in a self-aligning manner, so that the lead can cover 22 can be buckled with the lead can body 21 in a sealing manner.
In some embodiments, as shown in fig. 2 to 3, the maximum thickness D1 of the side wall of the lead can body 21 is smaller than the maximum thickness D2 of the side wall of the lead can cover 22, and the intersection of the inner surface of the side wall of the lead can cover 22 and the first outer surface 2221 has a round corner. By adopting the design, the problem that the sharp corner is easy to damage due to the fact that the sharp corner is formed at the intersection of the inner surface of the side wall of the lead can cover body 22 and the first outer surface 2221 when the lead can cover body and the lead can body are buckled in a self-aligning mode under the condition that the maximum thickness of the side wall of the lead can body is equal to the maximum thickness of the side wall of the lead can cover body can be avoided.
Specifically, in some embodiments, an inner surface of a side wall of the lead can cover 22 is parallel to the axis m2 of the lead can cover 22, an inner side wall of the first accommodating space 2111 is parallel to the axis m1 of the lead can body 21, and when the lead can cover 22 is fastened on the lead can body 21, the inner surface of the side wall of the lead can cover 22 is closer to the axis m2 of the lead can body than the inner side wall of the first accommodating space 2111.
In some embodiments, the outer surface 222 of the side wall of the lead can cover 22 further includes a second outer surface 2222 and a third outer surface 2223, and the third outer surface 2223 is located between the second outer surface 2222 and the first outer surface 2221. When the lead can cover 22 is fastened to the lead can body 21, the second outer surface 2222 is coplanar with the outer side wall of the lead can body 21, and the third outer surface 2223 is matched and attached to the top surface of the side wall of the lead can body 21.
In some embodiments, the third outer surface 2223 is perpendicular to the axis m2 of the lead can cover 22, and the top surface of the side wall of the lead can body 21 is perpendicular to the axis m1 of the lead can body 21.
In some embodiments, the lead can is made of lead-antimony alloy, so that the lead can be manufactured by stamping. Specifically, in the lead-antimony alloy, the content of antimony is between 3% and 4%, the hardness of the lead-antimony alloy with the content is moderate, and a lead can be manufactured in a stamping mode. Compared with the injection molding process adopted in the related art, the stamping process disclosed by the disclosure can reduce the production cost and improve the production efficiency. And the lead can manufactured by adopting the stamping mode can avoid the defects of slag inclusion, air holes and/or shrinkage cavities and the like of the lead can.
In some embodiments, the outer surface of the lead can is coated with a protective paint to protect the operator from direct exposure of the lead to the operator.
Some embodiments of the present disclosure also provide for use of the container of the previous embodiments in transferring radioactive particles, for example, use of the container of the previous embodiments in transferring radioactive particles using a two-needle system.
The flowchart and block diagrams in the figures illustrate the architecture, functionality, and operation of possible implementations of systems, methods and computer program products according to various embodiments of the present disclosure. In this regard, each block in the flowchart or block diagrams may represent a module, segment, or portion of code, which comprises one or more executable instructions for implementing the specified logical function(s). It should also be noted that, in some alternative implementations, the functions noted in the block may occur out of the order noted in the figures. For example, two blocks shown in succession may, in fact, be executed substantially concurrently, or the blocks may sometimes be executed in the reverse order, depending upon the functionality involved. It will also be noted that each block of the block diagrams and/or flowchart illustration, and combinations of blocks in the block diagrams and/or flowchart illustration, can be implemented by special purpose hardware-based systems which perform the specified functions or acts, or combinations of special purpose hardware and computer instructions.
Finally, it should be noted that: the embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The system or the device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
The above examples are only intended to illustrate the technical solution of the present disclosure, not to limit it; although the present disclosure has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present disclosure.
Claims (10)
1. A lead pig for the transport of a radiopharmaceutical, said lead pig comprising:
the lead tank comprises a lead tank body, wherein an open accommodating groove is formed in the lead tank body, and the accommodating groove comprises a first accommodating space and a second accommodating space which are sequentially far away from the bottom of the accommodating groove and are sequentially adjacent; and
a lead can cover body having a groove,
when the lead can cover body is buckled on the lead can body, the accommodating groove and the groove form an accommodating part, at least one part of the side wall of the lead can cover body is accommodated in the second accommodating space, and the maximum thickness of the side wall of the lead can body is smaller than that of the side wall of the lead can cover body.
2. The lead can according to claim 1, wherein, in a direction of an axis of the lead can body, an inner side wall of the second accommodating space gradually converges toward the axis of the lead can body as gradually approaching the first accommodating space,
the outer surface of the side wall of the lead can cover includes a first outer surface that gradually converges toward the axis of the lead can cover as it gradually moves away from the top surface of the lead can cover in the direction of the axis of the lead can cover,
when the lead can cover body is buckled on the lead can body, the first outer surface is matched and attached with the inner side wall of the second accommodating space, so that the axis of the lead can body is collinear with the axis of the lead can cover body.
3. The lead can of claim 2, wherein the intersection of the inner surface of the side wall of the lead can cover and the first outer surface has a rounded corner.
4. The lead can of claim 3, wherein an inner surface of the side wall of the lead can cover is parallel to an axis of the lead can cover, the inner side wall of the first receiving space is parallel to an axis of the lead can body,
when the lead can cover body is buckled on the lead can body, the inner surface of the side wall of the lead can cover body is closer to the axis of the lead can body relative to the inner side wall of the first accommodating space.
5. The lead can of claim 2, wherein the exterior surface of the side wall of the lead can cover further comprises a second exterior surface and a third exterior surface, the third exterior surface being located between the second exterior surface and the first exterior surface,
when the lead can cover body is buckled on the lead can body, the second outer surface is coplanar with the outer side wall of the lead can body, and the third outer surface is matched and attached with the top surface of the side wall of the lead can body.
6. The lead can according to any one of claims 1 to 5, wherein the lead can is made of lead-antimony alloy so that the lead can be manufactured by stamping.
7. The lead can of any one of claims 1 to 5, wherein the outer surface of the lead can is coated with a protective paint.
8. The lead can according to any one of claims 1 to 5, wherein the lead can is made of lead-antimony alloy.
9. A transport container for a radiopharmaceutical, comprising:
a vial configured to hold a radiopharmaceutical;
the lead can of any one of claims 1 to 8, configured to receive the vial;
a liquid-absorbing sponge configured to wrap the lead can to absorb the leaked liquid;
a metal sealed can configured to receive the lead can wrapped by the wicking sponge;
a buffer protective layer configured to wrap the metal can; and
a corrugated carton configured to accommodate the metal sealed can wrapped by the buffer protective layer,
the surface of the lead can containing the medicine bottle is subjected to thermoplastic sealing, so that the outer surface of the lead can is wrapped with a thermoplastic sealing film.
10. The shipping container of claim 9, wherein the material of the metal containment tank is a corrosion resistant material.
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| CN202222451405.XU CN218214665U (en) | 2022-09-15 | 2022-09-15 | Lead can and transport container |
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| CN202222451405.XU CN218214665U (en) | 2022-09-15 | 2022-09-15 | Lead can and transport container |
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