CN218157944U - Blood coagulation measuring device - Google Patents

Abstract

The utility model discloses a blood coagulation determination device relates to medical equipment technical field. The utility model discloses a blood coagulation measuring device, including base and the sample test module of setting on the base and educate the warm module, the sample test module includes first determine module and second determine module, and first determine module and second determine module can receive the blood coagulation cup from educating the warm module respectively to sample to in the blood coagulation cup detects, and first determine module and second determine module are L type and distribute, educate the warm module and lie in first determine module and second determine module and enclose and close the space that forms. The utility model provides a blood coagulation determination device, which comprises a first detection component and a second detection component, wherein the first detection component and the second detection component can respectively and independently receive a blood coagulation cup from a temperature raising module, can synchronously perform optical detection, and improves the instrument flux; meanwhile, the layout between the sample detection module and the temperature raising module is compact, so that the blood coagulation measuring device can be miniaturized.

Description

Blood coagulation measuring device

Technical Field

The utility model relates to the technical field of medical equipment, particularly, relate to a blood coagulation survey device.

Background

The blood coagulation measuring device is an automated instrument for analyzing blood coagulation and anticoagulation, fibrinolysis and anti-fibrinolysis functions, and generally comprises a preheating module, a sample adding module, a timing module, a sample transmitting and processing module, a detection module, a computer system and the like.

Currently, the market places ever higher demands on the testing speed and the spatial dimensions of coagulation assay devices. The existing blood coagulation measuring device has higher testing flux and can meet the requirement of testing speed, but has larger overall dimension, occupies more space and is inconvenient to use in narrow departments. Some devices have small size and small occupied space, but have small testing flux and low automation degree, and influence the detection efficiency of hospital departments.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a blood coagulation survey device has great flux and less volume.

The embodiment of the utility model is realized like this:

a blood coagulation measuring device comprises a base, and a sample detection module and a temperature raising module which are arranged on the base, wherein the sample detection module comprises a first detection assembly and a second detection assembly, the first detection assembly and the second detection assembly can respectively receive a blood coagulation cup from the temperature raising module and detect a sample in the blood coagulation cup, the first detection assembly and the second detection assembly are distributed in an L shape, and the temperature raising module is positioned in a space formed by enclosing the first detection assembly and the second detection assembly.

Optionally, the sample detection module further includes a light source assembly, the light source assembly is located between the base and the first detection assembly, the light source assembly includes a light source, a light path system located in a light exit direction of the light source, and a plurality of optical fibers connected to an end of the light path system, the light path system is configured to integrate light beams emitted by the light source, and the optical fibers are configured to conduct the integrated light beams; first determine module and second determine module all include a plurality of sense channels, are equipped with detection station on the detection channel, and detection station is used for placing the blood coagulation cup, and the export of a plurality of optic fibres sets up with a plurality of multibeam detection station one-to-one, and the light beam by the optic fibre outgoing shines on detection station's blood coagulation cup.

Optionally, the blood coagulation cup processing device further comprises a sample introduction module, a blood coagulation cup processing module and a blood coagulation cup placing module which are arranged on the base; advance kind module and blood coagulation cup processing module and distribute along the first direction, blood coagulation cup processing module, blood coagulation cup place the module, educate warm module and second detecting component and distribute along the second direction in proper order, advance kind module, educate warm module and first detecting component and distribute along the first direction, the width direction of advancing kind module is parallel with the first direction, the length direction of advancing kind module is parallel with the second direction.

Optionally, the blood coagulation cup storage device further comprises a first reagent storage module and a second reagent storage module which are arranged on the base, the first reagent storage module and the sample injection module are arranged in parallel, the first reagent storage module is located between the sample injection module and the blood coagulation cup placement module, the blood coagulation cup placement module is annular, and the second reagent storage module is located in an annular space of the blood coagulation cup placement module.

Optionally, the blood coagulation cup transfer module is arranged on the base, and comprises an empty cup transfer component, an intermediate transfer component, a first detection transfer component and a second detection transfer component; the empty cup transfer assembly is positioned between the coagulation cup processing module and the coagulation cup placing module and used for transferring the coagulation cup in the coagulation cup processing module to the coagulation cup placing module; the middle transfer assembly is positioned between the coagulation cup placing module and the temperature raising module and is used for transferring a coagulation cup in the coagulation cup placing module to the temperature raising module or transferring the coagulation cup in the coagulation cup placing module to a first cup throwing position; the first detection transfer component is positioned on one side of the first detection component close to the coagulation cup processing module and is used for realizing the sequential transfer of coagulation cups among the temperature raising module, the first starting reagent sample adding station, the first detection component and the first cup losing position; the second detection transfer assembly is positioned at one end of the second detection assembly close to the first detection assembly and is used for realizing the sequential transfer of the blood coagulation cups among the temperature raising module, the second starting reagent sample adding station, the second detection assembly and the second cup losing position; the first reagent sample adding station is positioned on the side face of the first detection assembly, the second reagent sample adding station is positioned on the side face of the second detection assembly, the first cup losing position is positioned between the temperature raising module and the first detection assembly, and the second cup losing position is positioned between the temperature raising module and the blood coagulation cup placing module.

Optionally, the sample loading module is arranged on the base and comprises a puncture needle assembly, a sample separating needle assembly, a first detection reagent needle assembly and a second detection reagent needle assembly; the puncture needle assembly is positioned between the sample injection module and the coagulation cup placing module and is used for adding a reagent in the sample injection module into a coagulation cup in the coagulation cup placing module; the sample separating needle assembly is positioned between the coagulation cup placing module and the first reagent storage module and is used for separating a sample in a coagulation cup in the coagulation cup placing module into a new coagulation cup or transferring a first reagent in the first reagent storage module into the coagulation cup in the coagulation cup placing module; the first detection reagent needle assembly is positioned between the coagulation cup placing module and the first detection assembly and is used for transferring the second reagent in the second reagent storage module into the coagulation cup in the Wen Mo cultivating block or transferring the second reagent in the second reagent storage module into the coagulation cup in the first detection assembly; the second detection reagent needle assembly is positioned between the coagulation cup placing module and the second detection assembly and is used for transferring the second reagent in the second reagent storage module into the coagulation cup in the Wen Mo cultivating block or transferring the second reagent in the second reagent storage module into the coagulation cup in the second detection assembly.

Optionally, the first reagent storage module comprises a support seat, and a first reagent driving motor and a first reagent moving part which are arranged on the support seat, the first reagent moving part comprises a plurality of first reagent placing positions and at least one emergency sample placing position, and the first reagent driving motor is used for moving the first reagent moving part to the movement path of the sample dispensing needle assembly.

Optionally, the second reagent storage module comprises a reagent storage module housing, and a reagent tray, a reagent tray driving mechanism, a reagent bottle scanning mechanism, a reagent refrigeration mechanism and a stirring mechanism which are arranged in the reagent storage module housing; the reagent dish is used for holding the cup of congealing blood, and reagent dish actuating mechanism is connected and drives the reagent dish and rotates with the reagent dish, is equipped with the notch on the reagent dish, and scanning mechanism passes through the bar code information on the notch scanning cup of congealing blood, and reagent cold storage mechanism is used for the cup cooling of congealing blood on the reagent dish, and rabbling mechanism is used for stirring the reagent in the cup of congealing blood.

Optionally, the coagulation cup processing module comprises an empty cup storage mechanism, an empty cup transfer mechanism, an empty cup conveying mechanism and a cup grabbing position; the empty cup storage mechanism comprises a cup pouring slideway and a storage container, and an outlet of the cup pouring slideway is positioned at an inlet of the storage container; the empty cup transfer mechanism comprises an empty cup transfer driving motor and an empty cup transfer executing component, and the empty cup transfer executing component is used for transferring the blood coagulation cup in the storage container to the inlet of the empty cup conveying mechanism under the driving of the empty cup transfer driving motor; the empty cup conveying mechanism comprises a slide way inclined from the empty cup transferring mechanism to a cup grabbing position, the cup grabbing position comprises a cup falling station, a detection station and a cup grabbing station, the cup falling station is connected with an outlet of the slide way, the blood coagulation cup enters the cup falling station through the slide way, the detection station is provided with a detection sensor, the detection sensor is used for detecting whether an empty cup exists in the cup grabbing position, and the cup grabbing station is located on a motion path of the empty cup transferring mechanism.

Optionally, the temperature raising module is annular, the temperature raising module is uniformly provided with a cup feeding position, an intermediate reagent sample feeding position, a first detection grabbing position and a second detection grabbing position, the cup feeding position is located on a movement path of the empty cup transfer assembly, the intermediate reagent sample feeding position is located on a movement path of the intermediate transfer assembly, the first detection grabbing position is located on a movement path of the first detection transfer assembly, and the second detection grabbing position is located on a movement path of the second detection transfer assembly.

Optionally, the blood coagulation cup placing module includes an empty cup placing position, a puncture needle sample adding position, a sample separating needle sample adding position and a sample sucking position, a temperature raising transfer position and an abnormal sample detecting position, the empty cup placing position is located on the side of the cup grasping position of the blood coagulation cup processing module, the puncture needle sample adding position is located on the movement path of the puncture needle assembly, the sample separating needle sample adding position and the sample sucking position are located on the rotation path of the sample separating needle assembly, the temperature raising transfer position is located on the side of the temperature raising module and on the movement path of the middle transfer assembly, an optical path detecting mechanism is arranged on the abnormal sample detecting position, and the optical path detecting mechanism is used for detecting an abnormal sample.

Optionally, the sample introduction module comprises a pushing mechanism, a sample rack conveying mechanism, a code scanning mechanism, a puncture positioning mechanism, a pushing mechanism and a retesting mechanism; the pushing mechanism is provided with a sample rack to-be-detected area, the sample rack to-be-detected area is used for placing a plurality of sample racks distributed in rows, each sample rack is provided with a plurality of sample tubes, the sample rack conveying mechanism is used for conveying the sample racks, a conveying channel of each sample rack is provided with a conveying starting point position, a sample and sample rack bar code identification position, a puncture position and a conveying end point position, and the sample rack conveying mechanism is used for conveying the sample racks to the conveying starting point position, the sample and sample rack bar code identification position, the puncture position and the conveying end point position in sequence; the code scanning mechanism identifies the bar code information of the sample tube, the puncture positioning mechanism is used for pre-positioning the sample tube to be punctured and sucked, the pushing mechanism is used for recovering the sample frame for completing sample detection, and the retesting mechanism is used for sending the sample frame recovered by the pushing mechanism back to the pushing mechanism again.

The utility model discloses beneficial effect includes:

the utility model provides a blood coagulation measuring device, including base and the sample test module of setting on the base and educate the warm module, the sample test module includes first determine module and second determine module, and first determine module and second determine module can receive the blood coagulation cup from educating the warm module respectively to sample to in the blood coagulation cup detects, and first determine module and second determine module are L type and distribute, educate the warm module and lie in first determine module and second determine module and enclose and close the space that forms. The sample detection module in the blood coagulation measuring device comprises a first detection component and a second detection component, the first detection component and the second detection component can respectively and independently receive the blood coagulation cup from the temperature raising module, optical detection can be synchronously performed, and instrument flux is improved; meanwhile, the layout between the sample detection module and the temperature raising module is compact, so that the blood coagulation measuring device can be miniaturized.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.

FIG. 1 is a schematic view of a coagulation measuring device according to an embodiment of the present invention;

fig. 2 is a schematic structural view of a first detection module in the blood coagulation measurement device according to an embodiment of the present invention;

FIG. 3 is a schematic structural view of a temperature-raising module in the blood coagulation measuring device according to the embodiment of the present invention;

fig. 4 is a schematic structural diagram of a sample injection module in the blood coagulation measuring device according to an embodiment of the present invention;

FIG. 5 is a schematic structural diagram of a coagulation cup processing module in the coagulation assay device according to an embodiment of the present invention;

fig. 6 is a schematic structural diagram of a blood coagulation cup placement module in the blood coagulation measuring device according to an embodiment of the present invention;

fig. 7 is a schematic structural view of a first reagent storage block in the coagulation measuring apparatus according to the embodiment of the present invention;

fig. 8 is a schematic structural view of a second reagent storage block in the coagulation measuring device according to the embodiment of the present invention;

fig. 9 is a schematic structural view of a lancet assembly in a coagulation measuring device according to an embodiment of the present invention.

Icon: 100-a coagulation assay device; 110-a base; 111-first cup lost position; 112-a second cup lost position; 121-a first detection component; 1211 — a detection channel; 122-a second detection component; 130-a temperature raising module; 131-a cup entering position; 132-intermediate reagent loading position; 133-first detection grab position; 134-second detection grab position; 140-sample introduction module; 141-a propulsion mechanism; 142-a sample rack transport mechanism; 143-code scanning mechanism; 144-a puncture positioning mechanism; 145-a push-out mechanism; 146-retest mechanism; 150-a coagulation cup processing module; 151-empty cup storage mechanism; 152-an empty cup transfer mechanism; 153-empty cup transport mechanism; 154-cup grasping position; 160-a coagulation cup placement module; 161-empty cup placement position; 162-sample loading position of puncture needle; 163-sample adding position and sample sucking position of the sample separating needle; 164-temperature raising shift; 165-abnormal sample detection bit; 170-a first reagent storage module; 171-a support base; 172-a first reagent drive motor; 173-a first reagent moving part; 1731-first reagent placement site; 1732 — urgent sample placement bit; 180-a second reagent storage module; 181-reagent storage module housing; 182-reagent tray; 183-reagent refrigeration mechanism; 191-an empty cup transfer assembly; 192-an intermediate transfer assembly; 193-a first test transfer assembly; 194-a second test transfer assembly; 210-an introducer needle assembly; 211-puncture needle; 220-a sample dispensing needle assembly; 230-a first detector reagent needle assembly; 240-a second detector reagent needle assembly; 300-sample holder.

Detailed Description

To make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the attached drawings in the embodiments of the present invention are combined to clearly and completely describe the technical solution in the embodiments of the present invention, and obviously, the described embodiments are part of the embodiments of the present invention, rather than all embodiments. The components of embodiments of the present invention, as generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the invention, as presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person of ordinary skill in the art without paying creative work belong to the protection scope of the present invention.

It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.

In the description of the present invention, it should be noted that the terms "vertical", "horizontal", and the like indicate the orientation or the positional relationship based on the orientation or the positional relationship shown in the drawings, which are only for convenience of description of the present invention and simplification of description, and should not be construed as limitations of the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance. The terms "disposed," "mounted," "connected," and "connected" are to be construed broadly and may, for example, be fixedly connected or detachably connected; may be directly connected or indirectly connected through an intermediate. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Referring to fig. 1 to 3, the present embodiment provides a blood coagulation measuring device 100, including a base 110, and a sample detecting module and a temperature raising module 130 disposed on the base 110, where the sample detecting module includes a first detecting component 121 and a second detecting component 122, the first detecting component 121 and the second detecting component 122 can respectively receive a blood coagulation cup from the temperature raising module 130, and detect a sample in the blood coagulation cup, the first detecting component 121 and the second detecting component 122 are distributed in an L-shape, and the temperature raising module 130 is located in a space surrounded by the first detecting component 121 and the second detecting component 122.

The base 110 is used for installing a sample detection module and a temperature raising module 130, and the temperature raising module 130 is used for raising the temperature of the sample in the temperature coagulation cup within a required range, so that the sample is in an optimal reaction condition; in the temperature raising process, an intermediate reagent and a starting reagent required by the reaction can be added into the coagulation cup to trigger the agglutination reaction; the blood coagulation cup is immediately transferred to the first detecting component 121 or the second detecting component 122, and the reaction process of the sample is detected by the first detecting component 121 or the second detecting component 122 to obtain the reaction result. The first detecting component 121 and the second detecting component 122 are independent parts, and can respectively perform optical detection on the sample in the blood coagulation cup from the temperature raising module 130 to obtain the detection parameters. The first detecting component 121 and the second detecting component 122 are distributed in an L shape to form a right-angled corner, and the temperature raising module 130 is disposed in the right-angled corner, so as to fully utilize the space formed by the enclosure of the first detecting component 121 and the second detecting component 122 and facilitate the transfer of the coagulation cup in the temperature raising module 130 to the first detecting component 121 or the second detecting component 122. Illustratively, as shown in fig. 1, the first detecting component 121 is located at the rear side of the base 110, the second detecting component 122 is located at the right side of the base 110, and the temperature-raising module 130 is disposed near the right rear corner of the base 110.

In this embodiment, the structure of the temperature raising module 130 is not limited as long as the temperature raising module can raise the temperature of the coagulation cup containing the sample. Similarly, the first and second detecting units 121 and 122 are not limited in structure as long as the sample can be optically detected.

The sample detection module in the blood coagulation measuring device 100 includes a first detection assembly 121 and a second detection assembly 122, the first detection assembly 121 and the second detection assembly 122 can respectively and independently receive the blood coagulation cups from the incubation module 130, and can synchronously perform optical detection, thereby improving instrument throughput; at the same time, the layout between the sample detection module and the incubation module 130 is compact, and the coagulation assay device 100 can be miniaturized.

Referring to fig. 1 and fig. 2, optionally, in an implementation manner of the embodiment of the present invention, the sample detection module further includes a light source assembly, the light source assembly is located between the base 110 and the first detection assembly 121, the light source assembly includes a light source, a light path system located in a light emitting direction of the light source, and a plurality of optical fibers connected to an end of the light path system, the light path system is used for integrating light beams emitted by the light source, and the optical fibers are used for conducting the integrated light beams; the first detecting component 121 and the second detecting component 122 both include a plurality of detecting channels 1211, the detecting channels 1211 are provided with detecting stations, the detecting stations are used for placing the blood coagulation cups, the outlets of the plurality of optical fibers and the plurality of multi-beam detecting stations are arranged in a one-to-one correspondence manner, and the light beams emitted by the optical fibers irradiate on the blood coagulation cups of the detecting stations.

The front end of the light path system is positioned in the light emitting direction of the light source, and light beams emitted by the light source are integrated by the light path system after entering the light path system; the tail end of the optical path system is connected with an inlet of the optical fiber, the optical fiber is divided into a plurality of beams from one beam and provided with a plurality of outlets, and the integrated beams are divided into a plurality of beams and are respectively emitted from the plurality of outlets of the optical fiber. The optical fiber outlets are located at the detection stations of the detection channel 1211, each detection station corresponds to one optical fiber outlet, the first detection assembly 121 and the second detection assembly 122 share the same light source assembly, and the integrated light beam emitted from the optical fiber outlets can irradiate on the blood coagulation cup located on the detection station, so that the first detection assembly 121 and the second detection assembly 122 optically detect a sample in the blood coagulation cup located on the detection station through absorbance change. The light source detecting component is located below the first detecting component 121, so as to make full use of the position between the first detecting component 121 and the base 110, so that the layout perpendicular to the surface direction of the base 110 is more compact, the space on the surface of the base 110 is saved, the mounting position is reserved for other modules, and the miniaturization of the coagulation measuring device 100 is facilitated.

Referring to fig. 1, 4 to 6, optionally, in an implementation manner of the embodiment of the present invention, the sample injection module 140, the coagulation cup processing module 150, and the coagulation cup placement module 160 are further included on the base 110; the sample introduction module 140 and the coagulation cup processing module 150 are distributed along a first direction, the coagulation cup processing module 150, the coagulation cup placing module 160, the temperature raising module 130 and the second detection assembly 122 are sequentially distributed along a second direction, the sample introduction module 140, the temperature raising module 130 and the first detection assembly 121 are distributed along the first direction, the width direction of the sample introduction module 140 is parallel to the first direction, and the length direction of the sample introduction module 140 is parallel to the second direction.

The surface of the base 110 defines a first direction (a direction in fig. 1) and a second direction (B direction in fig. 1) perpendicular to each other. The sample introduction module 140, the coagulation cup processing module 150 and the coagulation cup placement module 160 are all arranged on the surface of the base 110, the sample introduction module 140 is used for realizing automatic conveying of samples, an operator only needs to place the samples into the sample rack 300 adapted to the sample introduction module 140, the sample introduction module 140 automatically conveys the sample rack 300, the sample introduction efficiency is improved, and further the working efficiency of the coagulation determination device 100 is improved; the coagulation cup processing module 150 has a cup grasping position 154, the coagulation cup processing module 150 automatically conveys a new coagulation cup to the cup grasping position 154, and the coagulation cup at the cup grasping position 154 is subsequently transferred to the coagulation cup placing module 160; the coagulation cup placement module 160 has a plurality of empty coagulation cup placement positions for sample loading and sample separation.

The sample injection module 140 is rectangular, and the width direction of the sample injection module 140 is parallel to the first direction, and the length direction is parallel to the second direction; the sample detection module, the temperature raising module 130, the sample introduction module 140, the coagulation cup processing module 150 and the coagulation cup placement module 160 are all located on the same side of the sample introduction module 140, wherein the coagulation cup processing module 150, the coagulation cup placement module 160, the temperature raising module 130 and the second detection assembly 122 are sequentially distributed along a second direction, and the sample introduction module 140, the temperature raising module 130 and the first detection assembly 121 are sequentially distributed along a first direction. Illustratively, as shown in fig. 1, the surface of the base 110 has a rectangular shape, and the first direction and the second direction are respectively parallel to two mutually perpendicular edges of the surface of the base 110; the sample introduction module 140 is located at a position close to the edge of the front side of the base 110, the coagulation cup processing module 150 is located at the left rear side of the base 110, the coagulation cup placement module 160 is located at a position slightly left from the middle of the base 110, the first detection assembly 121 is located at the rear side of the base 110, the second detection assembly 122 is located at the right side of the base 110, and the temperature raising module 130 is located close to the right rear corner of the base 110.

First, in this embodiment, the structures of the sample injection module 140, the coagulation cup processing module 150, and the coagulation cup placement module 160 are not limited as long as they can realize their respective functions.

Second, the coagulation cup processing module 150, the coagulation cup placing module 160, the temperature raising module 130, and the second detecting component 122 are sequentially distributed along the second direction, but are not necessarily strictly distributed along a straight line, and may be arranged in a staggered manner. Illustratively, as shown in fig. 1, the distance between the center of coagulation cup placement module 160 and sample injection module 140 is smaller than the distance between the center of incubation module 130 and sample injection module 140.

Referring to fig. 1, fig. 7 and fig. 6, optionally, in an implementation manner of the embodiment of the present invention, the apparatus further includes a first reagent storage module 170 and a second reagent storage module 180 disposed on the base 110, the first reagent storage module 170 is disposed in parallel with the sample injection module 140, the first reagent storage module 170 is located between the sample injection module 140 and the coagulation cup placement module 160, the coagulation cup placement module 160 is annular, and the second reagent storage module 180 is located in an annular space of the coagulation cup placement module 160.

The first reagent storage module 170 is used for storing a diluent, a buffer solution, and a room temperature reagent such as an emergency sample, and the second reagent storage module 180 is used for storing a refrigerated reagent. The width direction of the first reagent storage module 170 is parallel to the first direction, the length direction is parallel to the second direction, and the first reagent storage module 170 is located between the sample injection module 140 and the coagulation cup placement module 160, so as to facilitate adding the first reagent to the coagulation cup placement module 160 or a coagulation cup in the sample injection module 140. The blood coagulation cup placing module 160 is configured to be annular, and different stations can be divided along the annular position of the blood coagulation cup placing module 160 according to the layout of each module, so that the blood coagulation cup can be transferred between the blood coagulation cup placing module 160 and the module adjacent to the blood coagulation cup placing module. The second reagent storage module 180 is disposed in the annular space of the coagulation cup placement module 160 to fully utilize the space on the surface of the base 110, so that the layout between the modules is more compact, which is advantageous for the miniaturization of the coagulation measuring device 100.

In this embodiment, the structures of the first reagent storage module 170 and the second reagent storage module 180 are not limited as long as the first reagent storage module and the second reagent storage module can store corresponding reagents and maintain the performance of the reagents to meet the detection requirements.

Referring to fig. 1, in order to realize the automatic transfer of the blood coagulation cup between the modules, optionally, in an implementation manner of the embodiment of the present invention, the blood coagulation cup transfer module further includes a blood coagulation cup transfer module disposed on the base 110, and the blood coagulation cup transfer module includes an empty cup transfer component 191, an intermediate transfer component 192, a first detection transfer component 193, and a second detection transfer component 194; each component is arranged between different modules and works independently without mutual interference.

Specifically, the empty cup transfer assembly 191 is located between the coagulation cup processing module 150 and the coagulation cup placement module 160, and is used for transferring the coagulation cup in the coagulation cup processing module 150 to the coagulation cup placement module 160. Illustratively, the empty coagulation cup transfer assembly may be configured to perform both horizontal and vertical movements for transferring an empty coagulation cup located in the cup grasping position 154 of the coagulation cup processing module 150 to an empty coagulation cup placement station of the coagulation cup placement module 160. The specific implementation mode is as follows: when the system prompts the coagulation cup placement module 160 to add a new coagulation cup, the detection sensor on the cup grasping position 154 of the coagulation cup processing module 150 detects whether an empty coagulation cup exists on the detection station, and if so, the empty coagulation cup on the detection station is transferred to the cup grasping station. The system controls the empty cup transfer component 191 to move to the position above the cup grabbing station, controls the clamping component on the empty cup transfer component 191 to move downwards to clamp the empty coagulation cup, then lifts the empty coagulation cup upwards to move the empty coagulation cup out of the cup grabbing station, then moves the empty coagulation cup to the position above the placing station of the coagulation cup placing module 160, and controls the clamping component to move downwards to place the coagulation cup on the placing station.

An intermediate transfer assembly 192 is positioned between the coagulation cup placement module 160 and the incubation module 130 for transferring a coagulation cup in the coagulation cup placement module 160 to the incubation module 130 or transferring a coagulation cup in the coagulation cup placement module 160 to the first cup-lost position 111. Illustratively, the intermediate transfer assembly 192 can perform movements in both horizontal and vertical directions for transferring a coagulation cup with a sample located at the temperature raising transfer station in the coagulation placement module to the cup feeding station in the temperature raising module 130, or for transferring a coagulation cup with a specific sample detection located at the temperature raising transfer station in the coagulation placement module to the first cup discarding position 111 for discarding. The specific implementation mode is as follows: when a certain coagulation cup in the coagulation cup placement module 160 is added with a sample and a buffer solution, the system controls the coagulation cup placement module 160 to transfer the coagulation cup to the temperature raising transfer station; then the clamping component of the middle transferring component 192 moves to the position above the temperature raising transferring station, moves downwards to clamp the blood coagulation cup with the sample, then the clamping component is lifted upwards to enable the blood coagulation cup to be separated from the temperature raising transferring station, then the blood coagulation cup is transferred to the position above the cup feeding station in the temperature raising module 130, and finally moves downwards to place the blood coagulation cup with the sample. Or when a certain coagulation cup in the coagulation cup placing module 160 is located, after the abnormal sample is detected, the system controls the coagulation cup placing module 160 to transfer the reaction cup to the temperature raising transfer station; then the clamping component of the middle transferring component 192 moves to the position above the temperature raising and transferring station, moves downwards to clamp the blood coagulation cup with the sample, then the clamping component is lifted upwards to enable the blood coagulation cup to be separated from the temperature raising and transferring station, then the blood coagulation cup is transferred to the position above the first cup losing position 111, and finally moves downwards to place the blood coagulation cup with the sample, and the blood coagulation cup can fall into the receiving container along the first cup losing channel.

The first detection transfer component 193 is located at a side of the first detection component 121 close to the blood coagulation cup processing module 150, and is used for realizing sequential transfer of blood coagulation cups among the incubation module 130, the first reagent loading starting station, the first detection component 121 and the first cup losing position 111. For example, the first detection transferring component 193 can realize movements in three directions, i.e., horizontal, front-back and vertical, and is used to transfer the incubated coagulation cup at the first detection grasping station in the incubation module 130 to the first start reagent loading station near the first detection component 121, or transfer the coagulation cup in the first start reagent loading station to the detection station on the first detection component 121, or transfer the coagulation cup in the first detection component 121 to the first cup discarding position 111. The specific implementation mode is as follows: when a certain blood coagulation cup in the incubation module 130 is incubated and a starting reagent is added, the system controls the incubation module 130 to transfer the reaction cup to the first detection cup grabbing station, then the clamping part of the first detection transfer component 193 moves to the position above the first detection grabbing station, then moves downwards to one side of the blood coagulation cup, and then the clamping part moves towards the blood coagulation cup to clamp the blood coagulation cup. Then, the clamping component carries the blood coagulation cup to move upwards, the blood coagulation cup is separated from the temperature raising module 130, and then the clamping component moves to a first starting reagent sample adding station; adding a starting reagent into the blood coagulation cup at a first starting reagent adding position, quickly shaking up a sample in the blood coagulation cup by the clamping component, and then moving to a detection position of the first detection assembly 121; after the first testing component 121 completes testing the sample, the holding member continues to transport the sample to the first cup discarding position 111 for discarding.

The second detection transfer component 194 is located at one end of the second detection component 122 close to the first detection component 121, and is used for sequentially transferring the blood clotting cups among the temperature raising module 130, the second reagent start-up sample application station, the second detection component 122 and the second cup losing position 112; the second reagent loading position is located at the side of the first detecting component 121, the first cup-discarding position 111 is located between the incubation module 130 and the first detecting component 121, and the second cup-discarding position 112 is located between the incubation module 130 and the coagulation cup placement module 160. The second detection transfer component 194 is similar in function to the first detection transfer component 193 and will not be described in detail herein.

The selection of the positions of the empty cup transfer set 191, the intermediate transfer set 192, the first detection transfer set 193, and the second detection transfer set 194 makes full use of the space between the modules, resulting in a more compact and smaller coagulation assay device 100.

In this embodiment, the structures of the empty cup transfer unit 191, the intermediate transfer unit 192, the first detection transfer unit 193, and the second detection transfer unit 194 are not limited as long as they can transfer the blood cups at different positions.

Referring to fig. 1 and fig. 9, optionally, in an implementation manner of the embodiment of the present invention, the blood coagulation analyzer further includes a sample adding module disposed on the base 110, wherein the sample adding module is used for sucking and discharging a sample, a reagent, a diluent, a buffer solution, etc., and can add the sample, a normal temperature reagent, a cold storage reagent, the diluent, and the buffer solution into the blood coagulation cup; the sample adding module comprises a puncture needle assembly 210, a sample separating needle assembly 220, a first detection reagent needle assembly 230 and a second detection reagent needle assembly 240, and all the components are arranged at different positions and work independently without interfering with each other.

Specifically, the puncture needle assembly 210 is located between the sample injection module 140 and the coagulation cup placement module 160, and is used for adding the reagent in the sample injection module 140 into the coagulation cup in the coagulation cup placement module 160. Illustratively, the needle assembly 210 may be movable in two degrees of freedom, rotation and elevation; when a sample is sucked, the puncture needle assembly 210 rotates to the position above a puncture station of the sample injection module 140, then the sample is injected into the sample tube, after the sample is sucked, the puncture needle assembly 210 is lifted, in the lifting process, the outer wall of the puncture needle 211 is cleaned, then the sample is rotated to the position above a sample injection position of the blood coagulation cup placing module, and then the sample is injected into a new blood coagulation cup. After the sample is applied, the needle assembly 210 is moved to the cleaning position for cleaning, and then the next sample is aspirated. Alternatively, for samples that have multiple items to be tested, the lancet assembly 210 can aspirate a sufficient amount of sample at a time to be added to the coagulation cup to improve the efficiency of the test. Optionally, when the instrument is connected to the production line for detection, the puncture needle assembly 210 may also rotate to the outside of the instrument to a position above the sample suction position of the production line for sample suction.

The sample dispensing needle assembly 220 is located between the coagulation cup placement module 160 and the first reagent storage module 170, and is used for dispensing the sample in the coagulation cup placement module 160 into a new coagulation cup, or transferring the first reagent in the first reagent storage module 170 into the coagulation cup in the coagulation cup placement module 160. Illustratively, the dispensing needle assembly 220 may achieve two degrees of freedom of movement, rotation and elevation. If a plurality of detection items exist in one sample, the sample distributing needle assembly 220 can distribute the sample in the blood coagulation cup positioned at the sample adding station of the puncture needle 211 on the blood coagulation cup placing module 160, and the sample is distributed into different new blood coagulation cups according to the sample testing amount of different items. Alternatively, if the items of diluent and buffer solution are added, the sample dispensing needle assembly 220 rotates to a position above the first reagent suction position to suck the first reagent, and then the first reagent is added into the coagulation cup. Optionally, a sample separating needle cleaning component is further disposed on a rotation path of the sample separating needle component 220, and after the sample separating needle component 220 completes a sample separating action, the sample separating needle component rotates into the cleaning component to clean the inner wall and the outer wall of the needle.

The first testing reagent needle assembly 230 is located between the coagulation cup placement module 160 and the first testing component 121, and is used for transferring the second reagent in the second reagent storage module 180 into the coagulation cup in the incubation module 130, or transferring the second reagent in the second reagent storage module 180 into the coagulation cup in the first testing component 121; the second testing reagent needle assembly 240 is located between the coagulation cup placement module 160 and the second testing component 122 for transferring the second reagent in the second reagent storage module 180 into the coagulation cup in the incubation module 130 or transferring the second reagent in the second reagent storage module 180 into the coagulation cup in the second testing component 122. Both the first and second detection reagent needle assemblies 230 and 240 may aspirate all types of reagents from the second reagent storage module 180. During the blood coagulation item detection, one or more reagents need to be added for reaction in the incubation process, a start reagent needs to be added before the optical detection, so that the optical detection can be performed, and the first detection reagent needle assembly 230 and the second detection reagent needle assembly 240 can realize the transfer of the reagent from the second reagent storage module 180 to the blood coagulation cup in the incubation module 130 and the addition of the start reagent before the detection.

The second reagent storage module 180 is located inside the blood coagulation cup placing module 160, stores various cold storage reagents, and the sample adding module is matched with the module, so that the required cold storage reagents can be rapidly transferred to a reagent sample sucking position of the sample adding module. The first reagent storage module 170 is located at the front side of the base 110 and used for storing first reagents such as diluent and buffer solution and emergency samples, and the sample adding module is also matched with the first reagent storage module 170 to move, so that samples can be quickly sucked and transferred.

The selection of the positions of the puncture needle assembly 210, the sample dispensing needle assembly 220, the first measurement reagent needle assembly 230, and the second measurement reagent needle assembly 240 makes full use of the gaps between the modules, resulting in a more compact and smaller coagulation measurement device 100.

In the present embodiment, the puncture needle assembly 210, the sample dispensing needle assembly 220, the first detection reagent needle assembly 230, and the second detection reagent needle assembly 240 are not limited in structure as long as they can perform their respective functions.

Referring to fig. 7, alternatively, in an implementation manner of the embodiment of the present invention, the first reagent storage module 170 includes a supporting seat 171, and a first reagent driving motor 172 and a first reagent moving part 173 which are disposed on the supporting seat 171, the first reagent moving part 173 includes a plurality of first reagent placing positions 1731 and at least one emergency sample placing position 1732, and the first reagent driving motor 172 is used for moving the first reagent moving part 173 to a movement path of the sample dispensing needle assembly 220.

For example, when a first reagent or an emergency sample needs to be aspirated, the first reagent driving motor 172 drives the first reagent moving part 173 to move to the moving path of the sample dispensing needle assembly 220, and the sample dispensing needle assembly 220 performs a sample aspiration operation again.

Referring to fig. 8, optionally, in an implementation manner of the embodiment of the present invention, the second reagent storage module 180 includes a reagent storage module housing 181, and a reagent disk 182, a reagent disk 182 driving mechanism, a reagent bottle scanning mechanism, a reagent refrigerating mechanism 183, and an agitating mechanism disposed in the reagent storage module housing 181; reagent dish 182 is used for holding the blood coagulation cup, and reagent dish 182 actuating mechanism is connected and drives reagent dish 182 and rotates with reagent dish 182, is equipped with the notch on the reagent dish 182, and scanning mechanism passes through the bar code information on the blood coagulation cup of notch scanning, and cold-stored mechanism 183 of reagent is used for cooling down the blood coagulation cup on the reagent dish 182, and rabbling mechanism is used for stirring the reagent in the blood coagulation cup.

The reagent storage module housing 181 serves to position and support the entire module and is mounted on the base 110. Illustratively, the outer peripheral surface of the reagent storage module housing 181 is wrapped with a layer of heat insulation cotton to insulate the reagent bottle from heat exchange with the outside. A reagent disk 182 driving mechanism is arranged on the reagent storage module casing 181, optionally, the reagent disk 182 driving mechanism may be a motor-matched synchronous pulley transmission structure, or a gear structure, and the reagent disk 182 driving mechanism drives the reagent disk 182 to rotate.

The reagent tray 182 is used to hold coagulation cups, and illustratively, the reagent tray 182 includes a plurality of reagent storage racks of the same structure, a reagent storage rotating member, and a storage rack dividing member. The reagent storage supports may be arranged in a fan-shaped configuration and positioned on the reagent storage rotating member, and a plurality of reagent storage supports having a fan-shaped configuration are partitioned by the storage support partition to form a complete circle. The reagent disk 182 driving mechanism drives the reagent storage rotating member to rotate, thereby driving the reagent storage rack to rotate. The reagent storage support is provided with a plurality of storage positions for placing reagent bottles with different specifications, and optionally, the reagent storage support is provided with 3 circles of storage positions which are annularly arranged along the radial direction so as to increase the storage capacity of the reagent bottles. The purpose of this setting is to cooperate the application of sample module to carry out the sample of reagent's suction.

Illustratively, the second reagent storage module 180 includes a first reagent needle mechanism inner loop pipetting site, a first reagent needle mechanism middle pipetting site, a first reagent needle mechanism outer loop pipetting site, a second reagent needle mechanism inner loop pipetting site, a second reagent needle mechanism middle loop pipetting site, and a second reagent needle outer loop pipetting site. When the reagent is sucked, the second reagent storage block 180 rotates the sample sucking position to the movement path of the first reagent needle mechanism and the second reagent needle mechanism, and the first reagent needle mechanism and the second reagent needle mechanism operate to suck the reagent.

Illustratively, the reagent storage rack is further provided with a handle, and when all the reagent bottles need to be taken out at one time or put into the reagent tray 182, the reagent storage rack is only required to be directly taken out, or the reagent bottles are filled in the reagent storage rack and then put into the reagent tray 182. The reagent storage positions of the inner ring, the middle ring and the outer ring of the reagent storage support are also provided with notches which are opened to the outer ring along the radial direction. The reagent bottle scanning mechanism is used for scanning bar code information on the reagent bottle. The reagent bottle scanning mechanism is fixedly disposed at one side of the second storage module, and when a reagent bottle is loaded into the apparatus, the reagent tray 182 rotates while the reagent bottle scanning mechanism operates, and when the notch of the reagent storage rack rotates to be opposite to the scanning position of the code scanning mechanism 143, the barcode information on the reagent bottle is read.

Illustratively, the reagent refrigeration mechanism 183 includes TEC heat fins, heat sinks, heat sink fans, convection fans, and air ducts. The TEC heat plate is used to generate a cold side and a hot side to lower the temperature in the reagent disk 182, the heat sink is used to transfer the heat of the TEC hot side to the air channel, and the heat sink fan exhausts the heat to the outside of the instrument. The convection fan blows cool air around the TEC cold side contact area to the reagent disk 182 to circulate air inside the reagent disk 182 to maintain temperature uniformity around the reagent disk 182.

Illustratively, the agitation mechanism includes an agitation drive motor and a magnetic agitation member. A plurality of reagent sites with stirring function are arranged in the second reagent storage module 180. The stirring mechanism is positioned below the reagent storage position with the stirring function. When the reagent bottle with the stirrer in the bottle is placed in the reagent position, the stirring driving motor drives the magnetic stirring component to rotate, and then the stirrer in the reagent bottle is driven to rotate, so that the reagent is stirred.

Referring to fig. 5, optionally, in an implementation manner of the embodiment of the present invention, the coagulation cup processing module 150 includes an empty cup storage mechanism 151, an empty cup transfer mechanism 152, an empty cup transport mechanism 153, and a cup grasping position 154. Specifically, the empty cup storage mechanism 151 includes a cup pouring slide and a storage container, and an outlet of the cup pouring slide is located at an inlet of the storage container; when adding new blood coagulation cups to blood coagulation cup processing module 150, operating personnel can empty the reaction cup from the inlet of the cup pouring slideway, the reaction cup slides into the storage container along the slideway, and the storage container can store a large number of blood coagulation cups. The empty cup transfer mechanism 152 includes an empty cup transfer driving motor and an empty cup transfer executing part, and the empty cup transfer executing part transfers the coagulation cup in the storage container to the inlet of the empty cup conveying mechanism 153 by the driving of the empty cup transfer driving motor; the empty cup transport mechanism 153 includes a chute inclined from the empty cup transfer mechanism 152 to a cup grasping position 154, the chute starting at a higher position and ending at the cup grasping position 154. The empty cup transfer executing component is driven by the empty cup transfer driving motor to transfer the coagulation cup in the storage container to the initial position of the slide way. The coagulation cup slides along the slide under the force of gravity to the cup grasping position 154. Illustratively, the slide is provided in a configuration for sliding a single coagulation cup. The cup grabbing position 154 comprises a cup falling position, a detection position and a cup grabbing position, the cup falling position is connected with an outlet of the slide way, the coagulation cup enters the cup falling position through the slide way, the detection position is provided with a detection sensor, the detection sensor is used for detecting whether an empty cup exists on the cup grabbing position 154, and the cup grabbing position is located on a motion path of the empty cup transferring component 191. If the sensor does not detect the dropping of the coagulation cup, the control system controls the empty cup transfer mechanism 152 to work, so that the coagulation cup drops from the storage mechanism. The coagulation cup at the cup grasping station is transferred by the coagulation cup transfer module to the placement position of the coagulation cup placement module 160.

Referring to fig. 1 and fig. 3, optionally, in an implementation manner of the embodiment of the present invention, the temperature raising module 130 is ring-shaped, the temperature raising module 130 is uniformly provided with a cup feeding position 131, an intermediate reagent feeding position 132, a first detection grabbing position 133, and a second detection grabbing position 134, the cup feeding position 131 is located on a motion path of the empty cup transfer component 191, the intermediate reagent feeding position 132 is located on a motion path of the first detection reagent needle component 230, the first detection grabbing position 133 is located on a motion path of the first detection transfer component 193, and the second detection grabbing position 134 is located on a motion path of the second detection transfer component 194.

The coagulation cup with the sample brought by the coagulation cup transfer module is placed in the cup entrance position 131. The intermediate reagent loading position 132 is located in the path of movement of the intermediate transfer assembly 192. When the sample in the incubation module 130 needs to be added with the intermediate reagent, the incubation module 130 can rotate the sample to the intermediate reagent adding position 132. The first detection reagent needle assembly 230 in the sample application module first sucks the intermediate reagent from the second reagent storage module 180, rotates to the intermediate reagent application position 132, and applies the sample to the cuvette. The first test grasping position 133 is located on the moving path of the first test transfer assembly 193 in the blood clotting cup transfer module. After the temperature of the sample is raised, the coagulation cup is clamped by the clamping member of the first detection transfer assembly 193 and transferred to the first start reagent loading position. Similarly, the coagulation cup in the second detection grasping position 134 and with the temperature raising completed is clamped by the clamping component of the second detection transferring component 194 in the coagulation cup transferring module, and then transferred to the second start reagent loading position.

Referring to fig. 1 and fig. 6, optionally, in an implementation manner of the embodiment of the present invention, the coagulation cup placement module 160 includes an empty cup placement position 161, a puncture needle sample injection position 162, a sample separation needle sample injection position and sample suction position 163, a temperature raising shift position 164, and an abnormal sample detection position 165; the empty cup placing position 161 is located on the side of the cup grabbing position 154 of the coagulation cup processing module 150 and is used for placing an empty coagulation cup from the cup grabbing position 154 of the coagulation cup processing module 150; the puncture needle sample adding position 162 is positioned on the movement path of the puncture needle assembly 210, and after the puncture needle assembly 210 absorbs a sample, the sample can move to the position above the puncture needle sample adding position 162, and then the sample is added by a lower needle; the sample application position and the sample suction position 163 of the sample distribution needle are located on the rotation path of the sample distribution needle assembly 220, if a sample with a plurality of test items and needing sample distribution is encountered, or a sample with a first reagent such as diluent and buffer solution is encountered, the coagulation cup placement module 160 rotates the sample to the sample application position of the sample distribution needle, the sample distribution needle assembly 220 rotates to the sample application position above the sample suction position of the sample distribution needle, and then the sample is placed on the sample discharge needle for suction and discharge; the temperature raising transfer part 164 is located on the side of the temperature raising module 130 and on the moving path of the middle transfer component 192, and the coagulation cup with the sample is transferred to the coagulation cup placement position of the temperature raising module 130 by the clamping part on the middle transfer component 192; the abnormal sample detection position 165 is provided with a light path detection mechanism, the light path detection mechanism is used for detecting abnormal samples, such as chyle, hemolysis and lipemia samples, and the light path detection mechanism can detect the samples.

Referring to fig. 1 and fig. 4, optionally, in an implementation manner of the embodiment of the present invention, the sample injection module 140 includes a pushing mechanism 141, a sample rack conveying mechanism 142, a code scanning mechanism 143, a puncturing positioning mechanism 144, a pushing mechanism 145, and a retesting mechanism 146; the propelling mechanism 141 is provided with a sample rack to-be-detected area, the sample rack to-be-detected area is used for placing a plurality of sample racks 300 distributed in rows, each sample rack 300 is provided with a plurality of sample tubes, the sample rack conveying mechanism 142 is used for conveying the sample racks 300, a conveying channel of each sample rack 300 is provided with a conveying starting point position, a sample and sample rack bar code identification position, a puncture position and a conveying end point position, and the sample rack conveying mechanism 142 is used for conveying the sample racks 300 to the conveying starting point position, the sample and sample rack bar code identification position, the puncture position and the conveying end point position in sequence; the code scanning mechanism 143 identifies the barcode information of the sample tube, and the puncture positioning mechanism 144 is used to pre-position the sample tube to be punctured and aspirated, so that the puncture needle assembly 210 can be smoothly inserted into the sample tube for aspiration; the pushing mechanism 145 is used for recovering the sample racks 300 subjected to sample detection, and a certain number of sample racks 300 subjected to sample detection can be placed on the pushing mechanism; illustratively, the pushing mechanism 145 is provided with a sample rack full detection device for automatically detecting the number of sample racks 300; the retesting mechanism 146 is used to return the specimen rack 300 retrieved by the pushing mechanism 145 back to the pushing mechanism 141.

Illustratively, the pushing mechanism 141 includes a driving motor, a transmission member, and a pushing member, wherein the transmission member is connected to the pushing member, and the pushing member can move back and forth under the driving of the driving motor, so as to push the sample rack 300 to the area of the sample rack transporting mechanism 142. The sample rack transport mechanism 142 is provided with a contact sensor for determining whether the sample rack 300 transported by the pushing mechanism 141 is in place. The sample rack transport mechanism 142 includes a transport drive motor and transport components. Optionally, the conveying member is a synchronous belt structure, two stoppers are arranged on the synchronous belt, and the distance between the stoppers is slightly greater than the total length of the sample rack 300. The pushing mechanism 141 pushes the sample rack 300 between the two stoppers, and the sample rack conveying mechanism 142 drives the sample rack 300 to move towards the code scanning station, the puncturing station and the recovery station.

Illustratively, the scanner mechanism 143 includes a scanner, which is vertically arranged on the specimen rack 300 transport path and can recognize barcode information on the specimen tube within the specimen rack 300, and a rotating member. The special bar code is pasted on the part at the position opposite to the code scanner, the information of the code is a blank code, and whether a sample tube is placed in the sample rack 300 at the code scanning station or not can be judged. If no sample tube is placed, the optical path emitted by the scanner will follow the aperture of the sample holder 300 and impinge on the special barcode. The rotating component can realize the automatic identification of the sample tube bar code. Typically, the barcodes are located only within a certain range of the outer circumferential surface of the sample tube, and the position of the sample tube within the sample holder 300 is random, i.e., the barcode on the sample tube does not necessarily face the barcode. The rotating part can realize that the sample tube at the code scanning station rotates around the axis of the sample tube, and in the rotating process, the code scanner identifies the bar code, so that the code scanner can automatically identify no matter where the bar code on the sample tube is located.

Illustratively, the puncture positioning mechanism 144 includes a puncture positioning driving motor, a sample tube positioning component and a puncture needle 211 outer wall cleaning component, the puncture positioning driving motor drives the sample tube positioning component to position and press a sample tube positioned on the puncture station, and then the puncture needle 211 is inserted into the sample tube to pipette the sample; after the sample is aspirated, the outer wall cleaning part of the puncture needle 211 cleans the outer wall of the needle contaminated by the sample in the process of lifting the puncture needle 211.

Illustratively, the push-out mechanism 145 includes a push-out driving part, a push-out executing part, and a recovery area. Alternatively, the push-out actuator may end in two flaps that push the sample rack 300 on the sample rack transport mechanism 142 into the retrieval area.

Illustratively, retest mechanism 146 includes a retest drive motor, a retest drive component, a retest contact sensor, a retest in-place sensor, and a retest limit component. The sample holder 300 is positioned on the retest transport member. The retest driving motor drives the retest transmission component to move, so as to drive the sample rack 300 to move towards the pushing mechanism 141, and finally move to the sample area to be tested. The retest contact sensor is used to determine whether the sample rack 300 has moved from the recovery area to the home position of the retest mechanism 146, and the retest position sensor is used to determine whether the sample rack 300 has moved to the sample area to be tested.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (12)

1. A coagulation measuring device (100) is characterized by comprising a base (110), and a sample detection module and a temperature raising module (130) which are arranged on the base (110), wherein the sample detection module comprises a first detection component (121) and a second detection component (122), the first detection component (121) and the second detection component (122) can respectively receive a coagulation cup from the temperature raising module (130) and detect a sample in the coagulation cup, the first detection component (121) and the second detection component (122) are distributed in an L shape, and the temperature raising module (130) is positioned in a space enclosed by the first detection component (121) and the second detection component (122).

2. The coagulation assay device (100) according to claim 1, wherein the sample detection module further comprises a light source assembly located between the base (110) and the first detection assembly (121), the light source assembly comprising a light source and an optical system located in a light emitting direction of the light source, and an optical fiber connected to an end of the optical system, an outlet of the optical fiber comprising a plurality of optical systems, the optical system being configured to integrate the light beam emitted from the light source, and the optical fiber being configured to conduct the integrated light beam; the first detection assembly (121) and the second detection assembly (122) both comprise a plurality of detection channels (1211), detection stations are arranged on the detection channels (1211), the detection stations are used for placing the coagulation cups, a plurality of outlets of the optical fibers and a plurality of multi-beam detection stations are arranged in a one-to-one correspondence mode, and light beams emitted by the optical fibers irradiate on the coagulation cups of the detection stations.

3. The coagulation assay device (100) according to claim 1, further comprising a sample introduction module (140), a coagulation cup processing module (150) and a coagulation cup placement module (160) disposed on the base (110); advance kind module (140) with it distributes along the first direction to congeal blood cup processing module (150), it handles module (150) to congeal blood cup place module (160) educate warm module (130) with second detection component (122) distributes along the second direction in proper order, advance kind module (140), educate warm module (130) with first detection component (121) are followed first direction distributes, advance the width direction of kind module (140) with first direction is parallel, the length direction of kind module (140) with the second direction is parallel.

4. The coagulation assay device (100) of claim 3, further comprising a first reagent storage module (170) and a second reagent storage module (180) disposed on the base (110), the first reagent storage module (170) disposed in parallel with the sample module (140), the first reagent storage module (170) positioned between the sample module (140) and the coagulation cup placement module (160), the first reagent storage module (170) disposed in parallel with the sample module (140), the coagulation cup placement module (160) having a ring shape, the second reagent storage module (180) positioned within the ring-shaped space of the coagulation cup placement module (160).

5. The coagulation assay device (100) of claim 4, further comprising a coagulation cup transfer module disposed on the base (110), the coagulation cup transfer module comprising an empty cup transfer component (191), an intermediate transfer component (192), a first detection transfer component (193), and a second detection transfer component (194);

the empty cup transfer assembly (191) is located between the coagulation cup processing module (150) and the coagulation cup placement module (160) for transferring a coagulation cup within the coagulation cup processing module (150) to the coagulation cup placement module (160);

the intermediate transfer assembly (192) is positioned between the coagulation cup placement module (160) and the temperature raising module (130) and is used for transferring a coagulation cup in the coagulation cup placement module (160) to the temperature raising module (130) or transferring a coagulation cup in the coagulation cup placement module (160) to a first cup losing position (111);

the first detection transfer component (193) is positioned on one side of the first detection component (121) close to the coagulation cup processing module (150) and is used for realizing sequential transfer of the coagulation cups among the temperature raising module (130), the first starting reagent loading station, the first detection component (121) and the first cup losing position (111);

the second detection transfer component (194) is positioned at one end of the second detection component (122) close to the first detection component (121) and is used for realizing the sequential transfer of the blood coagulation cups among the temperature raising module (130), the second starting reagent loading station, the second detection component (122) and the second cup losing position (112);

the first starting reagent feeding station is positioned on the side of the first detection assembly (121), the second starting reagent feeding station is positioned on the side of the second detection assembly (122), the first cup losing position (111) is positioned between the temperature raising module (130) and the first detection assembly (121), and the second cup losing position (112) is positioned between the temperature raising module (130) and the coagulation cup placing module (160).

6. The coagulation assay device (100) according to claim 5, further comprising a sample application module disposed on the base (110), the sample application module comprising a puncture needle assembly (210), a sample application needle assembly (220), a first detection reagent needle assembly (230), and a second detection reagent needle assembly (240);

the puncture needle assembly (210) is positioned between the sample feeding module (140) and the coagulation cup placing module (160) and is used for adding the reagent in the sample feeding module (140) into the coagulation cup in the coagulation cup placing module (160);

the sample dispensing needle assembly (220) is positioned between the coagulation cup placement module (160) and the first reagent storage module (170) and is used for dispensing a sample in a coagulation cup in the coagulation cup placement module (160) into a new coagulation cup or transferring a first reagent in the first reagent storage module (170) into a coagulation cup in the coagulation cup placement module (160);

the first detection reagent needle assembly (230) is positioned between the coagulation cup placement module (160) and the first detection assembly (121) and is used for transferring the second reagent in the second reagent storage module (180) into the coagulation cup in the incubation module (130) or transferring the second reagent in the second reagent storage module (180) into the coagulation cup in the first detection assembly (121);

the second assay reagent needle assembly (240) is located between the coagulation cup placement module (160) and the second assay assembly (122) for transferring a second reagent in the second reagent storage module (180) into a coagulation cup in the incubation module (130) or transferring a second reagent in the second reagent storage module (180) into a coagulation cup in the second assay assembly (122).

7. The coagulation assay device (100) according to claim 6, wherein the first reagent storage module (170) comprises a support base (171) and a first reagent driving motor (172) and a first reagent moving part (173) disposed on the support base (171), the first reagent moving part (173) comprising a plurality of first reagent placing locations (1731) and at least one emergency sample placing location (1732), the first reagent driving motor (172) for moving the first reagent moving part (173) onto a movement path of the sample dispensing needle assembly (220).

8. The coagulation assay device (100) according to claim 4, wherein the second reagent storage module (180) comprises a reagent storage module housing (181), and a reagent tray (182), a reagent tray (182) driving mechanism, a reagent bottle scanning mechanism, a reagent refrigerating mechanism (183), and an agitating mechanism provided within the reagent storage module housing (181);

reagent dish (182) are used for holding the coagulation cup, reagent dish (182) actuating mechanism with reagent dish (182) are connected and are driven reagent dish (182) rotate, be equipped with the notch on reagent dish (182), scanning mechanism passes through the notch scanning bar code information on the coagulation cup, cold-stored mechanism of reagent (183) are used for right the cooling of coagulation cup on reagent dish (182), rabbling mechanism is used for right the reagent in the coagulation cup stirs.

9. The coagulation assay device (100) according to claim 5, wherein the coagulation cup processing module (150) comprises an empty cup storage mechanism (151), an empty cup transfer mechanism (152), an empty cup transport mechanism (153), and a cup grasping position (154);

the empty cup storage mechanism (151) comprises a cup pouring slideway and a storage container, and an outlet of the cup pouring slideway is positioned at an inlet of the storage container; the empty cup transfer mechanism (152) comprises an empty cup transfer driving motor and an empty cup transfer executing component, and the empty cup transfer executing component is driven by the empty cup transfer driving motor to lower the coagulation cup in the storage container to be transferred to the inlet of the empty cup conveying mechanism (153); empty cup conveying mechanism (153) include by empty cup transfer mechanism (152) to grab the slide of cup position (154) slope, grab cup position (154) including the station of falling the cup, detect the station and grab the cup station, the station of falling the cup with the exit linkage of slide, the blood coagulation cup via the slide gets into the station of falling the cup, be equipped with detection sensor on the detection station, detection sensor is used for detecting whether there is empty cup on grabbing cup position (154), it is located to grab the cup station empty cup shifts on the motion path of subassembly (191).

10. The coagulation assay device (100) according to claim 5, wherein the temperature raising module (130) is annular, the temperature raising module (130) is uniformly provided with a cup feeding position (131), an intermediate reagent feeding position (132), a first detection grasping position (133) and a second detection grasping position (134), the cup feeding position (131) is located on a moving path of the empty cup transfer component (191), the intermediate reagent feeding position (132) is located on a moving path of the intermediate transfer component (192), the first detection grasping position (133) is located on a moving path of the first detection transfer component (193), and the second detection grasping position (134) is located on a moving path of the second detection transfer component (194).

11. The coagulation assay device (100) according to claim 6, wherein the coagulation cup placement module (160) comprises an empty cup placement position (161), a puncture needle placement position (162), a sample separating needle placement position and a sample sucking position (163), a temperature raising transfer position (164), and an abnormal sample detection position (165), the empty cup placement position (161) is located on the side of the cup grasping position (154) of the coagulation cup processing module (150), the puncture needle placement position (162) is located on the movement path of the puncture needle assembly (210), the sample separating needle placement position and the sample sucking position (163) are located on the rotation path of the sample separating needle assembly (220), the temperature raising transfer position (164) is located on the side of the temperature raising module (130) and the movement path of the intermediate transfer assembly (192), and the abnormal sample detection position (165) is provided with a light path detection mechanism for detecting an abnormal sample.

12. The coagulation assay device (100) according to claim 3, wherein the sample introduction module (140) comprises a pushing mechanism (141), a sample rack transport mechanism (142), a code scanning mechanism (143), a puncture positioning mechanism (144), a pushing mechanism (145) and a retesting mechanism (146);

the system comprises a propelling mechanism (141), a sample rack (300) to-be-detected area, a sample rack conveying mechanism (142) and a sample rack conveying mechanism (142), wherein the propelling mechanism (141) is provided with a sample rack (300) to-be-detected area, the sample rack (300) to-be-detected area is used for placing a plurality of sample racks (300) distributed in rows, each sample rack (300) is provided with a plurality of sample tubes, the sample rack conveying mechanism (142) is used for conveying the sample racks (300), a conveying starting point position, a sample and sample rack (300) bar code identification position, a puncture position and a conveying end point position are arranged on a conveying channel of each sample rack (300), and the sample rack conveying mechanism (142) is used for conveying the sample racks (300) to the conveying starting point position, the sample and sample rack (300) bar code identification position, the puncture position and the conveying end point position in sequence;

the code scanning mechanism (143) identifies the bar code information of the sample tube, the puncturing positioning mechanism (144) is used for pre-positioning the sample tube to be punctured and sucked, the pushing mechanism (145) is used for recovering the sample rack (300) completing sample detection, and the retesting mechanism (146) is used for re-conveying the sample rack (300) recovered by the pushing mechanism (145) to the pushing mechanism (141).

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