CN218113480U - Stability evaluation device for antibody sample - Google Patents

Abstract

The utility model discloses a stability evaluation device for antibody sample belongs to antibody detection technical field, including the device casing, the both sides inner wall of device casing all is provided with moving mechanism, two fixedly connected with is same between moving mechanism's the relative one side places the board, the one end of placing the board has been seted up and has been placed the mouth, the both sides inner wall of placing the mouth has all been seted up the spacing groove, one side inner wall fixedly connected with spacing spring of spacing groove, the one end fixedly connected with of spacing spring and the inner wall of spacing groove form sliding fit's stopper, the relative one side of stopper all is circular-arc structure, the top of stopper is the slope setting, the lower end orientation of stopper is placed the bottom inner wall of mouth, the equal fixedly connected with extrusion pad in relative one side of stopper, and the extrusion pad is the rubber material. The utility model discloses can be spacing to the culture dish core, realize the effect of protection sample.

Description

Stability evaluation device for antibody sample

Technical Field

The utility model belongs to the technical field of the antibody detects, especially, relate to a stability evaluation device for antibody sample.

Background

The antibody should be relatively stable in protein, and its Tm is substantially around 70 degrees. However, compared with other proteins, the antibody has instability as the property of the biological macromolecular protein, and can inactivate and degrade. The antibody is widely applied in the research and development and medical fields, for example, if the activity of the antibody is changed, unpredictable results can be caused, so that a complete detection method for the stability of the antibody is indispensable in the current antibody market, the available conditions and the effective period are determined by detection, and a stability evaluation device for an antibody sample is often required.

Among the prior art, a stability evaluation device for antibody sample generally includes full autoanalyzer casing, and the rack has been placed to the bottom inner wall of full autoanalyzer casing, generally will place the antibody sample in the culture dish on putting the rack to carry out the analysis aassessment to the sample.

However, when the device is placed, the culture dish is only supported by the placing frame, and the culture dish is prone to toppling over under the negligence of workers, so that the waste of samples is caused.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving the defects in the prior art and providing a stability evaluation device for an antibody sample. The advantages are that: can be limited to the culture dish core, and the effect of protecting the sample is realized.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

the utility model provides a stability evaluation device for antibody sample, includes the device casing, the both sides inner wall of device casing all is provided with moving mechanism, two fixedly connected with is the same board of placing between moving mechanism's the relative one side, the one end of placing the board has been seted up and has been placed the mouth, the both sides inner wall of placing the mouth has all been seted up the spacing groove, the spacing spring of one side inner wall fixedly connected with of spacing groove, the one end fixedly connected with of spacing spring and the inner wall of spacing groove form sliding fit's stopper.

Through the technical scheme: during the use, place the culture dish on placing the mouth, the inner wall of placing the mouth can carry on spacingly to the culture dish, in addition, the stopper can slide in the spacing inslot under the effort of spacing spring, can extrude the culture dish this moment, consequently, can carry on spacingly to the culture dish, realizes the effect of protection sample.

The utility model discloses further set up to, the relative one side of stopper all is circular-arc structure.

Through the technical scheme: the design that is circular-arc structure, area of contact between multiplicable stopper and the culture dish can make the culture dish fixed stable.

The utility model discloses further set up to, the top of stopper is the slope setting, the bottom inner wall of mouth is placed to the lower end orientation of stopper.

Through the technical scheme: the inclined culture dish is obliquely arranged, so that the contact surface between the top of the culture dish and the top of the limiting block is an inclined surface, and the culture dish is directly pressed in from the upper part of the limiting block when being installed.

The utility model discloses further set up to, the equal fixedly connected with extrusion pad in relative one side of stopper, and the extrusion pad is the rubber material.

Through the technical scheme: the setting of extrusion pad can multiplicable stopper and the frictional force between the culture dish, can make the culture dish place stably.

The utility model discloses further set up to, the relative one side of dummy block is all fixed the arch that is provided with a plurality of evenly distributed, and arch and dummy block integrated into one piece.

Through the technical scheme: the convex setting can increase the roughness on the extrusion pad surface, can further make the culture dish place stably.

The utility model discloses further set up to, moving mechanism includes two and places board fixed connection's slider, the spout that forms sliding fit with the slider has all been seted up to the both sides inner wall of device casing, the inner wall of spout is provided with slewing mechanism.

Through the technical scheme: the height of culture dish is adjusted so that when the analysis of sample is better in needs, make the slider slide in the spout through rotating-structure, and then drive the lift of culture dish.

The utility model discloses further set up to, slewing mechanism includes the threaded rod, one of them connect through the bearing between the top inner wall of spout and the threaded rod, and one of them slider cover is established on the threaded rod, and passes through threaded connection between one of them slider and the threaded rod, the rotation hole that extends to the spacing inslot wall is seted up to bottom outer wall one side of device casing, and the threaded rod extends to and rotates extraorally.

Through the technical scheme: when the height of the culture dish is adjusted, the threaded rod is rotated, the sliding block is limited by the sliding groove, and the sliding block can slide on the inner wall of the sliding groove.

The utility model has the advantages that:

1. this a stability evaluation device for antibody sample during the use, places the culture dish on placing the mouth, and the inner wall of placing the mouth can carry on spacingly to the culture dish, and in addition, the stopper can slide in the spacing groove under the effort of spacing spring, can extrude the culture dish this moment, consequently, can carry on spacingly to the culture dish, realizes the effect of protection sample.

2. This a stability evaluation device for antibody sample can make the contact surface between the top of culture dish and stopper be the inclined plane through the stopper that is the slope setting, and it can directly to impress the culture dish from the top of stopper when the installation.

3. This a stability evaluation device for antibody sample when adjusting the height of culture dish, the threaded rod rotates, and the slider receives the limiting displacement of spout this moment, and the slider can slide on the inner wall of spout.

Drawings

Fig. 1 is a schematic perspective view of a stability evaluation device for an antibody sample according to the present invention;

fig. 2 is a schematic partial sectional structural view of a stability evaluation device for an antibody sample according to the present invention;

FIG. 3 is an enlarged schematic view of the structure at A in FIG. 2;

fig. 4 is an enlarged schematic view of a portion B in fig. 2.

In the figure: 1. a device housing; 2. placing a plate; 3. a placement port; 4. a limiting groove; 5. a limiting spring; 6. a limiting block; 7. a pressing pad; 8. a protrusion; 9. a slider; 10. a chute; 11. a threaded rod; 12. the hole is rotated.

Detailed Description

The technical solution of the present patent will be described in further detail with reference to the following embodiments.

Reference will now be made in detail to embodiments of the present patent, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present patent and are not to be construed as limiting the present patent.

In the description of this patent, it is to be understood that the terms "center," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientations and positional relationships indicated in the figures, which are based on the orientations and positional relationships shown in the figures, and are used for convenience in describing the patent and for simplicity in description, but do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and therefore should not be construed as limiting the patent.

In the description of this patent, it is noted that unless otherwise specifically stated or limited, the terms "mounted," "connected," and "disposed" are to be construed broadly and can include, for example, fixedly connected, disposed, detachably connected, disposed, or integrally connected and disposed. The specific meaning of the above terms in this patent may be understood by those of ordinary skill in the art as appropriate.

Referring to fig. 1-4, a stability evaluation device for antibody sample, including device casing 1, the both sides inner wall of device casing 1 all is provided with moving mechanism, fixedly connected with is same between two moving mechanism's the relative one side place board 2, place the one end of board 2 and seted up and place mouthful 3, place the both sides inner wall of mouthful 3 and all seted up spacing groove 4, spacing spring 5 of one side inner wall fixedly connected with of spacing groove 4, spacing spring 5's one end fixedly connected with and spacing groove 4's inner wall forms sliding fit's stopper 6.

The opposite surfaces of the limiting blocks 6 are of circular arc structures, the tops of the limiting blocks 6 are arranged in an inclined mode, the lower ends of the limiting blocks 6 face the inner wall of the bottom of the placing opening 3, the opposite surfaces of the limiting blocks 6 are fixedly connected with the extrusion pads 7, the extrusion pads 7 are made of rubber materials, the contact area between the limiting blocks 6 and the culture dish can be increased through the limiting blocks 6 of the circular arc structures, and the culture dish can be fixed stably; the contact surface between the culture dish and the top of the limiting block 6 can be an inclined surface through the limiting block 6 which is arranged in an inclined manner, and the culture dish is directly pressed in from the upper part of the limiting block 6 when being installed; the friction force between the limiting block 6 and the culture dish can be increased through the extrusion pad 7, and the culture dish can be placed stably.

A plurality of evenly distributed bulges 8 are fixedly arranged on the opposite surface of the extrusion pad 7, the bulges 8 and the extrusion pad 7 are integrally formed, the moving mechanism comprises two sliding blocks 9 fixedly connected with the placing plate 2, sliding grooves 10 which are in sliding fit with the sliding blocks 9 are formed in the inner walls of the two sides of the device shell 1, the inner wall of each sliding groove 10 is provided with a rotating mechanism, each rotating mechanism comprises a threaded rod 11, the inner wall of the top of one sliding groove 10 is connected with the threaded rod 11 through a bearing, one sliding block 9 is sleeved on the threaded rod 11, one sliding block 9 is connected with the threaded rod 11 through a thread, one side of the outer wall of the bottom of the device shell 1 is provided with a rotating hole 12 extending to the inner wall of the limiting groove 4, the threaded rod 11 extends out of the rotating hole 12, the roughness of the surface of the extrusion pad 7 can be increased through the bulges 8, and the culture dish can be placed stably; when the height of the culture dish needs to be adjusted so as to better analyze a sample, the sliding block 9 slides in the sliding groove 10 through the rotating structure, and then the culture dish is driven to lift; when the height of the culture dish is adjusted, the threaded rod 11 is rotated, at the moment, the sliding block 9 is limited by the sliding groove 10, and the sliding block 9 can slide on the inner wall of the sliding groove 10.

The working principle is as follows: during the use, place the culture dish on placing mouthful 3, the inner wall of placing mouthful 3 can carry on spacingly to the culture dish, and in addition, stopper 6 can slide in spacing groove 4 under spacing spring 5's effort, can extrude the culture dish this moment, consequently, can carry on spacingly to the culture dish, realizes the effect of protection sample.

The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims (7)

1. The utility model provides a stability evaluation device for antibody sample, includes device casing (1), its characterized in that, the both sides inner wall of device casing (1) all is provided with moving mechanism, two fixedly connected with is same between moving mechanism's the relative one side places board (2), the one end of placing board (2) has been seted up and has been placed mouth (3), the both sides inner wall of placing mouth (3) has all been seted up spacing groove (4), one side inner wall fixedly connected with spacing spring (5) of spacing groove (4), the inner wall of the one end fixedly connected with of spacing spring (5) and spacing groove (4) forms sliding fit's stopper (6).

2. The stability evaluation device for antibody samples according to claim 1, wherein the opposite surfaces of the stopper (6) are arc-shaped.

3. The stability evaluation device for antibody samples according to claim 2, wherein the top of the stopper (6) is disposed obliquely, and the lower end of the stopper (6) faces the inner wall of the bottom of the placement opening (3).

4. The stability evaluation device for antibody samples according to claim 3, wherein the opposite surfaces of the limiting block (6) are fixedly connected with the pressing pads (7), and the pressing pads (7) are made of rubber.

5. The device for evaluating the stability of an antibody sample according to claim 4, wherein a plurality of protrusions (8) are uniformly distributed on each of the opposite surfaces of the dummy block (7), and the protrusions (8) and the dummy block (7) are integrally formed.

6. The stability evaluation device for antibody samples according to claim 1, wherein the moving mechanism comprises two sliding blocks (9) fixedly connected with the placing plate (2), the inner walls of both sides of the device housing (1) are respectively provided with a sliding groove (10) in sliding fit with the sliding blocks (9), and the inner walls of the sliding grooves (10) are provided with a rotating mechanism.

7. The stability evaluation device for the antibody sample according to claim 6, wherein the rotating mechanism comprises a threaded rod (11), one of the sliding grooves (10) is connected with the threaded rod (11) through a bearing, one of the sliding blocks (9) is sleeved on the threaded rod (11), one of the sliding blocks (9) is connected with the threaded rod (11) through a thread, one side of the outer wall of the bottom of the device shell (1) is provided with a rotating hole (12) extending to the inner wall of the limiting groove (4), and the threaded rod (11) extends out of the rotating hole (12).

Images