CN218106139U - Carotid intimal denudation experiment table - Google Patents
Carotid intimal denudation experiment table Download PDFInfo
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- CN218106139U CN218106139U CN202221173684.1U CN202221173684U CN218106139U CN 218106139 U CN218106139 U CN 218106139U CN 202221173684 U CN202221173684 U CN 202221173684U CN 218106139 U CN218106139 U CN 218106139U
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- Prior art keywords
- experiment table
- table body
- injector
- placing
- head
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- 238000002474 experimental method Methods 0.000 title claims abstract description 42
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 47
- 238000002347 injection Methods 0.000 claims abstract description 30
- 239000007924 injection Substances 0.000 claims abstract description 30
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims abstract description 25
- 229960002897 heparin Drugs 0.000 claims abstract description 25
- 229920000669 heparin Polymers 0.000 claims abstract description 25
- 230000007246 mechanism Effects 0.000 claims abstract description 9
- 241001465754 Metazoa Species 0.000 claims description 20
- 238000005406 washing Methods 0.000 claims description 11
- 239000011521 glass Substances 0.000 claims description 5
- 244000261422 Lysimachia clethroides Species 0.000 claims description 3
- 239000008280 blood Substances 0.000 abstract description 7
- 210000004369 blood Anatomy 0.000 abstract description 7
- 239000007788 liquid Substances 0.000 abstract description 3
- 230000002093 peripheral effect Effects 0.000 abstract description 3
- 230000023555 blood coagulation Effects 0.000 abstract description 2
- 238000004299 exfoliation Methods 0.000 abstract description 2
- 230000000007 visual effect Effects 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 9
- 208000026106 cerebrovascular disease Diseases 0.000 description 5
- 210000001715 carotid artery Anatomy 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 3
- 206010008118 cerebral infarction Diseases 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 206010072810 Vascular wall hypertrophy Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 208000037260 Atherosclerotic Plaque Diseases 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 201000007201 aphasia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000000302 ischemic effect Effects 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
A carotid intimal stripping experiment table comprises an experiment table body, wherein fixing columns are respectively fixed at four corners of the experiment table body, a placing groove is formed in the experiment table body and used for placing an injector, a clamping groove is formed in the placing groove, an end circular ring plate of the injector is located in the clamping groove, and a pushing mechanism is further arranged on the experiment table body and used for pushing a push rod of the injector; in summary, the utility model utilizes the injection mechanism to continuously inject the injector, so that the heparin water continuously flows out from the water injection hole through the water injection pipe, and the heparin water is sprayed to the operation area to avoid blood coagulation; the suction holes are also arranged to continuously suck peripheral oozing blood and oozing liquid, so that the operation visual field is ensured; the whole structure is simple, the experiment function is multiple, and the requirement of carotid intimal exfoliation experiment is met.
Description
Technical Field
The utility model belongs to the technical field of the medical treatment, concretely relates to carotid intimal denudation laboratory bench.
Background
Cerebrovascular diseases are one of the diseases with the highest incidence in China at present, and the daily life of patients is seriously affected by hemiplegia, aphasia and the like caused by affecting the functions of the brain after cerebral hemorrhage and cerebral infarction. For cerebral infarction, the cerebral infarction can be divided into in-situ emboli and ectopic emboli according to different emboli sources, the ectopic emboli are mostly emboli from shedding of heart and carotid artery, carotid intimal denudation is a method for removing thickened carotid intimal atherosclerotic plaque and preventing cerebral stroke caused by plaque shedding, and the method is proved to be an effective method for preventing and treating ischemic cerebrovascular disease.
In order to study the pathogenesis of carotid intimal thickening, an animal model of carotid intimal thickening was constructed, and then the animals' thickened carotid intima was removed for further experiments of protein differential expression, such as mass spectrometry to analyze the difference between the normal and disease groups. At present the animal place the laboratory bench body after the animal anesthesia when carrying out the carotid intima excision of bodiness on, carry out the carotid intima excision and need be partial one side with the head of animal, because the carotid is located the neck both sides, need the special position of fixed animal in the experimentation, and need be interrupted in the experimentation and spray the heparin water to the operation area, avoid blood to solidify, simultaneously need continuously attract peripheral oozing blood and sepage, guarantee the operation field of vision, do not have the laboratory bench body that is applicable to the carotid intima and strips specially at present, current laboratory bench body function is single, can not satisfy the experiment demand.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a carotid intima stripping test bench to solve do not have the test bench that is applicable to specially among the prior art carotid intima stripping, can spray heparin water in the experiment, and clear away the technical problem of sepage and oozing blood.
In order to achieve the above purpose, the utility model provides a carotid intima stripping experiment table's technical scheme is:
a carotid intimal stripping experiment table is characterized by comprising an experiment table body, wherein fixing columns are respectively fixed at four corners of the experiment table body, a placing groove is formed in the experiment table body and used for placing an injector, a clamping groove is formed in the placing groove, a circular plate at the end part of the injector is positioned in the clamping groove, a push plate and a push injection mechanism are further arranged on the experiment table body and used for pushing the push plate, and the push plate pushes a push rod of the injector;
the upper surface of the experiment table body is provided with two inclined grooves which are symmetrically arranged, a head cover is arranged above each inclined groove, one end of the head cover is hinged to the experiment table body through a pin shaft, a torsion spring is arranged on the pin shaft, the inclined grooves are used for placing animal heads, the corresponding head covers are used for limiting the animal heads in the inclined grooves, and the end parts of the head covers are of hook structures;
the injection end of syringe be connected with the water injection pipe, the end connection of water injection pipe has heparin water washing head, heparin water washing head utensil is used for placing the carotid by the arc wall, the water injection hole has been seted up to heparin water washing head, water injection pipe and water injection hole intercommunication.
Preferably, the heparin water washing head is provided with a suction hole, the suction hole is positioned at the bottom of the arc-shaped groove, and the suction hole is connected with a suction tube.
Preferably, two chutes are formed in the experiment table body, the two chutes are arranged side by side on the left and right sides of the experiment table body, a sliding block is arranged in each chute in a sliding mode, a threaded hole is formed in each sliding block, a threaded bolt is installed in the threaded hole of one sliding block, the upper end of each threaded bolt is connected with a magnifying lens through a gooseneck, and an LED lamp is arranged on the periphery of each magnifying lens.
Compared with the prior art, the beneficial effects of the utility model are that: the utility model utilizes the injection mechanism to continuously inject the injector, so that the heparin water continuously flows out of the water injection hole through the water injection pipe, and the heparin water is sprayed to the operation area to avoid blood coagulation; and the suction holes are also arranged to continuously suck peripheral oozing blood and oozing liquid, thereby ensuring the operation visual field; the device has simple integral structure and multiple experimental functions, and meets the requirement of carotid intimal exfoliation experiment.
Drawings
FIG. 1 is a schematic diagram of a carotid intimal denudation laboratory bench provided by the present invention;
FIG. 2 is a schematic structural view of a heparin water flushing head;
fig. 3 is a structural view of the magnifier.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not to be construed as limiting the invention, i.e., the described embodiments are merely illustrative of some, but not all, of the embodiments of the invention. The components of embodiments of the present invention, as generally described and illustrated in the figures herein, may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiment of the present invention, all other embodiments obtained by the person skilled in the art without creative work belong to the protection scope of the present invention.
It is noted that relational terms such as "first" and "second," and the like, may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, elements defined by the phrases "comprising a" \8230; "do not exclude processes, methods of including such elements.
In the description of the present invention, unless otherwise expressly specified or limited, the terms "mounted," "connected," and "connected" when they are used are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those skilled in the art through specific situations.
In the description of the present invention, it should be noted that, unless explicitly stated or limited otherwise, the term "provided" may be used in a broad sense, for example, the object of "provided" may be a part of the body, or may be arranged separately from the body and connected to the body, and the connection may be a detachable connection or a non-detachable connection. The specific meaning of the above terms in the present invention can be understood by those skilled in the art from the specific situation.
The present invention will be described in further detail with reference to examples.
The utility model provides a carotid intima stripping experiment table's concrete embodiment 1:
as shown in fig. 1 and 2, in this embodiment, a carotid intimal stripping experiment table includes an experiment table body 1, fixing columns 2 are respectively fixed at four corners of the experiment table body 1, a placement groove 3 is formed in the experiment table body 1, the placement groove 3 is used for placing an injector, a clamping groove 4 is formed in the placement groove 3, an end annular plate of the injector is located in the clamping groove 4, the clamping groove 4 prevents an injector of the injector from moving, a push plate and an injection mechanism 5 are further arranged on the experiment table body 1, the injection mechanism 5 is used for pushing the push plate, the push plate pushes a push rod of the injector, the injection mechanism 5 can be a rack and pinion structure, a lead screw nut transmission structure or a chain sprocket transmission structure, and the transmission structures are conventional technologies;
the upper surface of the experiment table body 1 is provided with two inclined groove bodies 6, the two inclined groove bodies 6 are symmetrically arranged, a head cover 7 is arranged above each inclined groove body 6, one end of each head cover 7 is hinged to the experiment table body 1 through a pin shaft, a torsion spring is arranged on each pin shaft, the inclined groove bodies 6 are used for placing animal heads, the corresponding head covers 7 are used for limiting the animal heads in the inclined groove bodies 6, and the end parts of the head covers 7 are of hook structures;
the injection end of syringe be connected with water injection pipe 9, the end connection of water injection pipe 9 has heparin water to wash head 10, heparin water washes head 10 utensil by arc wall 11, arc wall 11 is used for placing the carotid, water injection hole 12 has been seted up to heparin water washing head 10, water injection pipe 9 and water injection hole 12 intercommunication.
When the experiment is carried out, the animal is anesthetized, the limbs of the animal are fixed on the four fixing columns 2 through tethers, then the fixing position of the animal is selected according to the position of the carotid artery needing operation, if left carotid intima peeling operation is carried out, the head of the animal is deviated to the right side, and the left carotid artery is exposed. Set up two chute bodies 6 on the laboratory bench body 1 for place the animal head of slope, for keeping the animal head to be in the tilt state all the time at the experimentation, set up head lid 7 on laboratory bench body 1, head lid 7 can be with the restriction of animal head in chute body 6, and the couple structure of head lid 7 tip can be spacing to the animal head, prevents that the animal head from deviating from chute body 6. Place head 10 in the carotid below with heparin water washing during operation, the carotid is located arc 11, has heparin water in the syringe, installs the syringe in putting groove 3, starts the push rod that pushing mechanism 5 promoted the syringe, and heparin water flows into heparin water washing head 10 through water injection pipe 9, and final heparin water is flowed out by water injection hole 12, sprays heparin water to the operation region, avoids blood to solidify.
As another embodiment of the utility model, heparin water washes head 10 and has seted up and attract hole 13, attracts hole 13 to be located the bottom of arc wall 11, attracts hole 13 to be connected with and attracts pipe 14, attracts hole 13 to last the attraction to the water liquid that sprays and blood on every side, has guaranteed the operation field of vision.
As another embodiment of the utility model, as shown in fig. 3, two spouts 15 have been seted up on laboratory bench body 1, set up side by side about two spouts 15, and slidable mounting has slider 16 in every spout 15, sets up threaded hole on the slider 16, and double-screw bolt 17 is installed to one of them slider 16's screw hole screw thread, and double-screw bolt 17 upper end is connected with magnifying glass 19 through gooseneck 18, is provided with LED lamp 20 in magnifying glass 19's periphery. Because the carotid artery is only a few millimeters thick and is not easy to observe, the magnifying glass 19 and the LED lamp 20 are arranged on the experiment table body 1, so that illumination and observation are facilitated; the magnifying lens 19 can be installed in one of the sliding grooves 15 through the stud 17, and the observing position is convenient to adjust.
Claims (3)
1. A carotid intimal stripping experiment table is characterized by comprising an experiment table body, wherein fixed columns are respectively fixed at four corners of the experiment table body, a placing groove is formed in the experiment table body and used for placing an injector, a clamping groove is formed in the placing groove, a circular ring plate at the end part of the injector is positioned in the clamping groove, a push plate and a pushing mechanism are further arranged on the experiment table body and used for pushing the push plate, and the push plate pushes a push rod of the injector;
the upper surface of the experiment table body is provided with two inclined groove bodies, the two inclined groove bodies are symmetrically arranged, a head cover is arranged above each inclined groove body, one end of the head cover is hinged to the experiment table body through a pin shaft, a torsion spring is arranged on the pin shaft, the inclined groove bodies are used for placing animal heads, the corresponding head covers are used for limiting the animal heads in the inclined groove bodies, and the end parts of the head covers are hook structures;
the injection end of syringe be connected with the water injection pipe, the end connection of water injection pipe has heparin water washing head, heparin water washing head utensil is used for placing the carotid by the arc wall, heparin water washing head has seted up the water injection hole, water injection pipe and water injection hole intercommunication.
2. The carotid intimal stripping experimental bench according to claim 1, characterized in that the heparin water washing head is provided with a suction hole, the suction hole is positioned at the bottom of the arc-shaped groove, and the suction hole is connected with a suction tube.
3. The carotid intimal stripping experiment table as claimed in claim 1 or 2, wherein two sliding grooves are formed in the experiment table body, the two sliding grooves are arranged side by side left and right, a sliding block is slidably mounted in each sliding groove, a threaded hole is formed in each sliding block, a threaded bolt is mounted in the threaded hole of one sliding block, the upper end of the threaded bolt is connected with a magnifying glass through a gooseneck, and an LED lamp is arranged on the periphery of the magnifying glass.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221173684.1U CN218106139U (en) | 2022-05-17 | 2022-05-17 | Carotid intimal denudation experiment table |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221173684.1U CN218106139U (en) | 2022-05-17 | 2022-05-17 | Carotid intimal denudation experiment table |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218106139U true CN218106139U (en) | 2022-12-23 |
Family
ID=84498748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221173684.1U Expired - Fee Related CN218106139U (en) | 2022-05-17 | 2022-05-17 | Carotid intimal denudation experiment table |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218106139U (en) |
-
2022
- 2022-05-17 CN CN202221173684.1U patent/CN218106139U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20221223 |