CN218089403U - Temperature-controlled enzymolysis and efficient filtering device for collagen - Google Patents

Abstract

The utility model provides a collagen accuse temperature enzymolysis and high-efficient filter equipment, which comprises a tank body, jar body upside is equipped with the cover, the cover upper end is equipped with the charge door, the cover upside is equipped with first drive assembly and second drive assembly, jar internal side is equipped with the centrifugal sieve, centrifugal sieve upper end fixedly connected with support, support upper end fixedly connected with hollow shaft, the hollow shaft upper end is connected with second drive assembly, be equipped with the (mixing) shaft in the centrifugal sieve, the (mixing) shaft lateral wall is equipped with a plurality of stirring vane, the (mixing) shaft upper end is connected with first drive assembly, the slag tap hole has been seted up to the centrifugal sieve lower extreme, the slag tap hole is connected with slag tap pipe, the slag tap pipe lower extreme passes jar body, the slag tap pipe lower extreme is equipped with the filter residue discharge valve, jar body lower extreme is equipped with filtrating discharge valve. The utility model discloses can realize that collagen raw materials acid dissolves enzymolysis and collagen separation process and accomplish in same container, reduce the collagen raw materials and introduce more pollution in the transfer process repeatedly, the difficult jam of sieve mesh of centrifugal screen moreover.

Description

Temperature-controlled enzymolysis and efficient filtering device for collagen

Technical Field

The utility model belongs to the technical field of collagen biomaterial processing apparatus, concretely relates to collagen accuse temperature enzymolysis and high-efficient filter equipment.

Background

Collagen is a biological macromolecular material, is mainly obtained by two ways of animal tissue extraction and recombinant microorganism synthesis in production, the collagen obtaining modes all need centrifugation or filtration to remove impurities, and in the collagen impurity removal process, filtration is an impurity removal method which has low energy consumption and can be continuous and easy to industrialize compared with centrifugation.

The collagen raw material needs to be subjected to acid-soluble enzymolysis before filtration, and the acid-soluble enzymolysis and filtration of the existing treatment device are carried out by adopting two devices, so that more pollution can be introduced in the repeated transfer process, and the existing filtration device is easy to block.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a collagen accuse temperature enzymolysis and high efficiency filter equipment to solve the problem that the background art mentioned.

In order to achieve the purpose, the utility model provides a collagen accuse temperature enzymolysis and high efficiency filter equipment, which comprises a tank body, jar body upside is equipped with the cover, the cover upper end is equipped with the charge door, the cover upside is equipped with first drive assembly and second drive assembly, jar internal side is equipped with the centrifugal screen, centrifugal screen upper end fixedly connected with support, support upper end fixedly connected with hollow shaft, the hollow shaft upper end is connected with second drive assembly, be equipped with the (mixing) shaft in the centrifugal screen, the (mixing) shaft lateral wall is equipped with a plurality of stirring vane, the (mixing) shaft upper end is connected with first drive assembly, the hole of slagging tap has been seted up to the centrifugal screen lower extreme, the hole of slagging tap is connected with the pipe, the pipe lower extreme of slagging tap passes the jar body, the pipe lower extreme is equipped with the filter residue discharge valve, jar body lower extreme is equipped with the filtrating discharge valve.

Further, an inner scraper is attached to the inner side of the centrifugal screen and fixedly connected with the stirring shaft through a transmission rod.

Furthermore, the first driving assembly comprises a driving shell and a motor, the lower end of the driving shell is fixedly connected with the tank cover, the upper end of the stirring shaft is fixedly connected with an output shaft of the motor, and the motor is fixedly connected with the driving shell.

Furthermore, the second driving assembly comprises a first bevel gear and a second bevel gear, the upper end of the hollow shaft penetrates through the tank cover and is rotatably connected with the tank cover, the first bevel gear is fixed at the upper end of the hollow shaft, the second bevel gear is fixed at the upper end of the stirring shaft, a third bevel gear is arranged between the first bevel gear and the second bevel gear, the right end of the third bevel gear is rotatably connected with a threaded rod, and the right end of the threaded rod penetrates through the driving shell and is in threaded connection with the driving shell and the second bevel gear.

Further, the outside laminating of centrifugal screen is provided with outer scraper blade, outer scraper blade pass through the dead lever with jar body fixed connection.

Furthermore, the external side of jar fixedly connected with shell body, form the cavity between shell body and the external wall of jar, the shell body outside is equipped with medium import and medium export.

Furthermore, a thermometer is arranged on the upper side of the tank cover, and a temperature sensing probe of the thermometer is positioned in the tank body.

Furthermore, a control screen is arranged on the upper side of the tank cover.

Furthermore, cover upside fixedly connected with transmission arm one end, transmission arm other end fixedly connected with hydraulic stem, the hydraulic stem lateral wall is fixed in the shell body outside.

The utility model has the advantages that:

1. the utility model discloses can realize that the acid-soluble enzymolysis of collagen raw materials and collagen separation process accomplish in same container, reduce the collagen raw materials and introduce more pollution in the transfer process repeatedly, save time and manpower moreover, also avoided the material to shift the pollution that causes repeatedly and the remaining waste of material in the container.

3. The use of the separable coaxial reversing gear set utilizes the same-speed reverse rotation of the centrifugal screen and the stirring paddle, not only greatly improves the filtration efficiency, but also reduces the blocking probability of the screen holes of the centrifugal screen due to the rotation of the centrifugal screen, and is favorable for the separation of products of collagen after enzymolysis.

4. The scrapers on the two sides of the centrifugal screen rapidly scrape impurities such as swelling matters and micelles adhered to the screen wall and filtered collagen, screen mesh blockage is avoided, the collagen adhered to the outer wall after filtration is rapidly separated from the centrifugal screen, and filtering of the collagen is facilitated.

5. The cavity that forms between shell body and the external portion of jar can be through the medium in the low temperature constant temperature circulator, and the control jar interior reactant temperature can not only guarantee that the enzymolysis process is whole to be accorded with the optimum temperature of synthase, also can be when filtering, lets the enzymolysis products suitably increase the temperature under the condition that does not exceed collagen denaturation temperature, is favorable to increasing the mobility of collagen like this to further improve the filtration efficiency of collagen.

The present invention will be described in detail with reference to the accompanying drawings and examples.

Drawings

Fig. 1 is a schematic structural diagram of the present invention.

Fig. 2 is a schematic structural diagram of a second driving assembly.

Fig. 3 is a schematic view of the construction of the vacuum collection canister.

Fig. 4 is a schematic structural view of the hydraulic lever.

Description of reference numerals: 1. a tank body; 2. a can cover; 3. a feed inlet; 4. a first drive assembly; 401. a drive housing; 402. a motor; 5. a second drive assembly; 501. a first bevel gear; 502. a second bevel gear; 503. a third bevel gear; 504. a threaded rod; 6. centrifugal screening; 7. a support; 8. a hollow shaft; 9. a stirring shaft; 10. a slag discharge pipe; 11. filter residue discharge valve; 12. a filtrate discharge valve; 13. an inner scraper; 14. a transmission rod; 15. an outer squeegee; 16. fixing the rod; 17. an outer housing; 18. a media inlet; 19. a media outlet; 20. a thermometer; 21. a control screen; 22. a liquid adding port; 23. a stirring blade; 24. a hydraulic rod; 241. an electric motor; 242. a bidirectional gear pump; 243. an oil circuit integrated block; 244. an oil cylinder; 245. a piston; 25. a connection port; 26. a feed pipe; 27. a discharge pipe; 28. and a driving arm.

Detailed Description

To further illustrate the technical means and effects of the present invention adopted to achieve the predetermined purposes, the following detailed description of the embodiments, structural features and effects of the present invention will be made with reference to the accompanying drawings and embodiments.

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

In the description of the present invention, it is to be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "alignment", "overlap", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are merely for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, are not to be construed as limiting the present invention.

The terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature; in the description of the present invention, "a plurality" means two or more unless otherwise specified.

Example 1

The embodiment provides a collagen temperature-control enzymolysis and high-efficiency filtering device as shown in fig. 1, which comprises a tank body 1, wherein a tank cover 2 is arranged on the upper side of the tank body 1, a feed inlet 3 and a liquid adding port 22 are arranged at the upper end of the tank cover 2, a first driving assembly 4 and a second driving assembly 5 are arranged on the upper side of the tank cover 2, a centrifugal screen 6 is arranged on the inner side of the tank body 1, a support 7 is fixedly connected to the upper end of the centrifugal screen 6, a hollow shaft 8 is fixedly connected to the upper end of the support 7, the upper end of the hollow shaft 8 is connected with the second driving assembly 5, the second driving assembly 5 can drive the hollow shaft 8 to rotate, a stirring shaft 9 is arranged in the centrifugal screen 6, the side wall of the stirring shaft 9 is provided with a plurality of stirring blades 23, the upper end of the stirring shaft 9 is connected with the first driving assembly 4, the first driving assembly 4 can drive the stirring shaft 9 to rotate, a slag hole is formed in the lower end of the centrifugal screen 6, the slag hole is connected with a slag discharging pipe 10, the slag discharging pipe 10 is rotatably connected with a bearing, the lower end of the slag discharging pipe passes through the tank body 1, specifically, the lower end of the slag discharging pipe 10 is fixedly connected with the tank body 1, a filter residue discharging valve 11 is arranged at the lower end of the tank body 1, and a filtrate discharging valve 12 is arranged at the lower end of the tank body.

Further, as shown in fig. 1, the first driving assembly 4 includes a driving housing 401 and a motor 402, the lower end of the driving housing 401 is fixedly connected to the tank cover 2, the upper end of the stirring shaft 9 is fixedly connected to the output shaft of the motor 402, and the motor 402 is fixedly connected to the driving housing 401.

Further, as shown in fig. 1 and 2, the second driving assembly 5 includes a first bevel gear 501 and a second bevel gear 502, the upper end of the hollow shaft 8 passes through the tank cover 2 and is rotatably connected with the same, the first bevel gear 501 is fixed at the upper end of the hollow shaft 8, the second bevel gear 502 is fixed at the upper end of the stirring shaft 9, a third bevel gear 503 is arranged between the first bevel gear 501 and the second bevel gear 502, a threaded rod 504 is rotatably connected to the right end of the third bevel gear 503, and the right end of the threaded rod 504 passes through the driving housing 401 and is in threaded connection with the same; the threaded rod 504 can be rotated to drive the third bevel gear 503 to move in the radial direction, the meshing state of the third bevel gear 503 with the first bevel gear 501 and the second bevel gear 502 can be controlled, in the enzymolysis stage, the third bevel gear 503 is separated from the first bevel gear 501 and the second bevel gear 502, and the stirring shaft 9 is driven to rotate by the motor 402; in the filtering stage, the third bevel gear 503 is meshed with the first bevel gear 501 and the second bevel gear 502, and the first bevel gear 501 and the second bevel gear 502 rotate in opposite directions under the action of the third bevel gear 503, so that the centrifugal screen 6 and the stirring blades 23 rotate in opposite directions, the filtering efficiency is greatly improved due to the opposite rotation of the centrifugal screen 6, the blocking probability of the screen holes is reduced due to the rotation of the centrifugal screen 6, and the separation of products of collagen after enzymolysis is facilitated.

Further, as shown in fig. 1, an inner scraper 13 is attached to the inner side of the centrifugal screen 6 for scraping off attachments on the inner side of the centrifugal screen 6, the inner scraper 13 is fixedly connected with the stirring shaft 9 through a transmission rod 14, and two ends of the transmission rod 14 are fixed to the inner scraper 13 and the stirring shaft 9 through screws. The outer side laminating of centrifugal screen 6 is provided with outer scraper 15 for hang out the attached thing in the centrifugal screen 6 outside, outer scraper 15 through dead lever 16 with jar body 1 fixed connection. The scrapers on the inner side and the outer side of the centrifugal screen 6 quickly scrape impurities such as swelling matters and micelles adhered to the screen wall and filtered collagen, so that screen holes are prevented from being blocked, the collagen adhered to the outer wall after filtration is quickly separated from the centrifugal screen, and the filtration of the collagen is facilitated.

Further, as shown in fig. 1, an outer shell 17 is fixedly connected to the outer side of the tank body 1, a cavity is formed between the outer shell 17 and the outer wall of the tank body 1, and a medium inlet 18 and a medium outlet 19 are arranged on the outer side of the outer shell 17. The medium inlet 18 and the medium outlet 19 are communicated with the external low-temperature constant-temperature circulator through pipelines, the temperature in the tank cavity is controlled through medium circulation, the whole enzymolysis process can be ensured to meet the optimal temperature of enzyme, the degradation of a collagen structure and the loss of protein activity are avoided, the temperature of an enzymolysis product can be properly increased under the condition that the denaturation temperature of collagen is not exceeded, the mobility of collagen is favorably increased, and the filtration efficiency of the collagen is further improved.

Further, as shown in fig. 1, a thermometer 20 is provided on the upper side of the tank cover 2, a temperature sensing probe of the thermometer 20 is located in the tank body 1, and a control panel 21 is provided on the upper side of the tank cover 2. The thermometer 20 can detect the temperature in the tank 1, thereby facilitating the control of the temperature in the tank 1, and the control screen 21 facilitates the control of the operation of the device.

Further, one end of a transmission arm 28 is fixedly connected to the upper side of the tank cover 2, the other end of the transmission arm 28 is fixedly connected with a hydraulic rod 24, the hydraulic rod 24 is in the vertical direction, and the side wall of the hydraulic rod 24 is fixed to the outer side of the outer shell 17, specifically, as shown in fig. 4, the hydraulic rod 24 uses a motor 241 as a power source, and rotates forward (backward) through the motor 241, so that hydraulic oil is output through a bidirectional gear pump 242, and is sent to a working oil cylinder 244 through an oil circuit manifold 243 to realize the reciprocating motion of a piston rod 245, thereby controlling the tank cover 2 to lift (open and close), and the hydraulic rod 24 here can be replaced by other telescopic cylinders, such as an electric telescopic cylinder.

Further, as shown in fig. 3, the device further comprises a negative pressure collecting tank, the negative pressure collecting tank is connected with the lower end of the filtrate discharge valve 11 through a pipeline, a connecting port 25 connected with a vacuum pump is arranged at the upper end of the negative pressure collecting tank, negative pressure is provided through the vacuum pump, a feeding pipe 26 is arranged on the left side, and a discharging pipe 27 is arranged at the lower end of the negative pressure collecting tank.

During acid dissolution: the low-temperature constant-temperature circulator is opened to set the temperature to the optimal enzymolysis temperature of the collagen, and liquid body fluids such as acid liquor, purified water and the like are sequentially added from the liquid adding port 22 according to the proportion. The position of the third bevel gear 503 is adjusted so that the third bevel gear 503 is separated from the first bevel gear 501 and the second bevel gear 502, and the motor 402 drives the stirring blade 23 to uniformly mix the acid solution.

When enzymolysis is carried out: after liquid in the temperature sensing probe monitoring tank reaches the optimum enzymolysis temperature, motor 402 is closed, enzymolysis collagen raw materials and enzyme after the cleaning process are added from charge door 3, the stirring rotational speed is set, motor 402 is started, under the drive of stirring vane 23, the substrate and the enzyme are fully mixed all the time, and the centrifugal screen 6 is in a static state in the enzymolysis stage.

After the enzymolysis is finished, the motor 402 is turned off, the position of the third bevel gear 503 is adjusted, so that the third bevel gear 503, the first bevel gear 501 and the second bevel gear 502 are in a meshed state and are connected with the negative pressure collecting tank, the temperature in the tank is properly adjusted, and the fluidity of the enzymolysis mixture is improved. And then filtering is carried out, when filtering is carried out, the motor 402 is turned on, a filtrate outlet is opened, collagen liquid filtered by the centrifugal screen 6 after enzymolysis of the collagen raw material is quickly sucked into the negative pressure collection tank, the collagen liquid is accelerated to be screened quickly through tangential force formed by coaxial reversal of the centrifugal screen 6 and the stirring blades 23, impurities such as swelling matters, micelles and the like adhered to the inner wall of the screen are scraped by scraping blades in the centrifugal screen 6 at any time, the screen holes of the centrifugal screen are prevented from being blocked by the impurities, the collagen adhered to the outer wall after filtering is quickly separated from the centrifugal screen by the scraping walls of the outer scraping blades, and the flowing resistance of the collagen in the screen is further reduced.

The foregoing is a more detailed description of the present invention, taken in conjunction with specific preferred embodiments thereof, and it is not intended that the invention be limited to the specific embodiments thereof. To the utility model belongs to the technical field of ordinary technical personnel, do not deviate from the utility model discloses under the prerequisite of design, can also make a plurality of simple deductions or replacement, all should regard as belonging to the utility model discloses a protection scope.

Claims (9)

1. The utility model provides a collagen accuse temperature enzymolysis and high-efficient filter equipment, includes a jar body (1), jar body (1) upside is equipped with cover (2), cover (2) upper end is equipped with charge door (3), its characterized in that: cover (2) upside is equipped with first drive assembly (4) and second drive assembly (5), jar body (1) inboard is equipped with centrifugal screen (6), centrifugal screen (6) upper end fixedly connected with support (7), support (7) upper end fixedly connected with hollow shaft (8), hollow shaft (8) upper end is connected with second drive assembly (5), be equipped with (mixing) shaft (9) in centrifugal screen (6), (mixing) shaft (9) lateral wall is equipped with a plurality of stirring vane (23), (mixing) shaft (9) upper end is connected with first drive assembly (4), the hole of slagging tap has been seted up to centrifugal screen (6) lower extreme, the hole of slagging tap is connected with slag pipe (10), slag pipe (10) lower extreme passes jar body (1), slag pipe (10) lower extreme is equipped with filter residue discharge valve (11), jar body (1) lower extreme is equipped with filtrating discharge valve (12).

2. The device for temperature-controlled enzymolysis and high-efficiency filtration of collagen according to claim 1, wherein: an inner scraper (13) is attached to the inner side of the centrifugal screen (6), and the inner scraper (13) is fixedly connected with the stirring shaft (9) through a transmission rod (14).

3. The device for temperature-controlled enzymolysis and high-efficiency filtration of collagen according to claim 1, wherein: the first driving assembly (4) comprises a driving shell (401) and a motor (402), the lower end of the driving shell (401) is fixedly connected with the tank cover (2), the upper end of the stirring shaft (9) is fixedly connected with an output shaft of the motor (402), and the motor (402) is fixedly connected with the driving shell (401).

4. The device for temperature-controlled enzymolysis and high-efficiency filtration of collagen according to claim 3, wherein: the second driving assembly (5) comprises a first bevel gear (501) and a second bevel gear (502), the upper end of the hollow shaft (8) penetrates through the tank cover (2) and the hollow shaft (8) are rotationally connected, the first bevel gear (501) is fixed at the upper end of the hollow shaft (8), the second bevel gear (502) is fixed at the upper end of the stirring shaft (9), a third bevel gear (503) is arranged between the first bevel gear (501) and the second bevel gear (502), the right end of the third bevel gear (503) is rotationally connected with a threaded rod (504), and the right end of the threaded rod (504) penetrates through the driving shell (401) and the two are in threaded connection.

5. The device for temperature-controlled enzymolysis and high-efficiency filtration of collagen according to claim 2, wherein: the outside laminating of centrifugal screen (6) is provided with outer scraper blade (15), outer scraper blade (15) through dead lever (16) with jar body (1) fixed connection.

6. The device for temperature-controlled enzymolysis and high-efficiency filtration of collagen according to claim 1, wherein: the utility model discloses a jar body, including jar body (1), outer casing (17) are connected with in the outside fixedly, form the cavity between outer casing (17) and the jar body (1) outer wall, the outer casing (17) outside is equipped with medium import (18) and medium export (19).

7. The device for temperature-controlled enzymolysis and high-efficiency filtration of collagen according to claim 6, wherein: a thermometer (20) is arranged on the upper side of the tank cover (2), and a temperature sensing probe of the thermometer (20) is positioned in the tank body (1).

8. The device for temperature-controlled enzymolysis and high-efficiency filtration of collagen according to claim 1, wherein: the upper side of the tank cover (2) is provided with a control screen (21).

9. The device for temperature-controlled enzymolysis and high-efficiency filtration of collagen according to claim 6, wherein: cover (2) upside fixedly connected with transmission arm (28) one end, transmission arm (28) other end fixedly connected with hydraulic stem (24), hydraulic stem (24) lateral wall is fixed in the shell body (17) outside.

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