CN218036749U - Dissolution instrument operation cabinet - Google Patents

Abstract

The application relates to a dissolution instrument operating cabinet, which comprises a base, a box body and a temperature adjusting device. The box sets up in the base top, and the box is provided with holding chamber and ventilation groove, and the holding chamber is used for placing dissolving out the appearance. Temperature regulation apparatus includes fan, air-supply line and exhaust pipe, and the fan sets up in the base, and the air-supply line passes through ventilation groove intercommunication holding chamber and fan, and the exhaust pipe is through setting up air outlet intercommunication fan and the holding chamber in the holding intracavity, and the fan is used for driving air to flow to the air outlet along air-supply line, fan and exhaust pipe from ventilation groove. According to the technical scheme, in order to prevent part of toxic components from volatilizing in the dissolving process of the medicine, the dissolution instrument is placed in the closed box body. Simultaneously through setting up air-supply line and air outlet in the box, the fan exchanges heat with the external world in the base, can enough guarantee that the inside gas of box is not the outdiffusion, can also realize the self-loopa of air and carry out the elevating temperature, keeps the required invariable ambient temperature of medicine dissolution.

Description

Dissolution instrument operation cabinet

Technical Field

The application relates to the technical field of laboratory equipment, in particular to a dissolution instrument operating cabinet.

Background

With the development of medical drug technology, medical dissolution experiments using dissolution instruments are required in order to analyze the stability of drug components and the dissolution characteristics of drug packages.

In medical dissolution experiments, part of the drugs contain volatile toxic components, which creates a safety risk problem during the experiment. The experimenter can only protect himself by wearing the protective device by himself, but cannot prevent the toxic components of the drug from volatilizing into other experimental areas.

SUMMERY OF THE UTILITY MODEL

Therefore, it is necessary to provide a dissolution instrument operating cabinet aiming at the problem of volatilization of toxic components in the drug dissolution process.

A dissolution meter operating cabinet comprising: base, box, temperature regulation apparatus and controlling means. The box set up in the base top, the box includes a plurality of curb plates and door plant, the curb plate reaches the door plant surrounds and forms the holding chamber, with the base is connected be provided with the ventilation groove on the curb plate. Temperature regulation apparatus includes fan, air-supply line, exhaust pipe and air outlet, the fan set up in the base, the air-supply line reaches the exhaust pipe wears to locate the base, the air outlet set up in the holding intracavity is kept away from one side of ventilation groove, the air-supply line intercommunication the fan reaches the ventilation groove, the exhaust pipe intercommunication the fan reaches the air outlet, the fan is used for the driving air to follow the ventilation groove is followed the air-supply line the fan reaches the exhaust pipe to the air outlet flows. The control device comprises a controller, the controller is in communication connection with the fan, and the controller can control the working power of the fan.

According to the technical scheme, the dissolving environment of the medicine is simulated through the temperature regulating device and the control device, and the medicine is kept at room temperature or the temperature in a human body. In order to prevent volatilization of part of toxic components in the dissolving process, the dissolving-out instrument is placed in a closed box body, and meanwhile, the air inlet pipe and the air outlet are arranged in the accommodating cavity, so that the self-circulation of air is realized and the temperature is increased and decreased on the premise that the gas in the box body is not diffused outwards, and the constant environment temperature required by the dissolution of the medicine is kept.

In one embodiment, a support rod is arranged in the ventilation groove, two ends of the support rod are fixedly connected to the inner wall of the ventilation groove, and the dissolution instrument is arranged on the support rod.

Above-mentioned technical scheme through will dissolving out the appearance and set up on the bracing piece of ventilation groove, can control the ambient temperature who dissolves out the appearance better, avoids dissolving out the actual temperature of appearance and producing great error with the calibration temperature.

In one embodiment, the support rods are arranged in the ventilation groove in parallel and at equal intervals along the horizontal direction.

Above-mentioned technical scheme, through setting up many spinal branchs vaulting pole into bars shape structure, the draft groove is when having sufficient draught area in order to keep the draft groove ventilation effect, and the appearance can be dissolved out in the help and set up in inside more stably, improves the installation stability of dissolving out the appearance.

In one embodiment, the temperature adjusting device further includes an air inlet, the air inlet communicates with the ventilation groove and the air inlet pipe, and a diameter of an end of the air inlet communicating with the ventilation groove is larger than a diameter of an end of the air inlet communicating with the air inlet pipe.

Above-mentioned technical scheme sets up the diameter at the both ends with the air intake into different sizes, can go out at the air intake and produce great pressure differential, improves the effect of bleeding of air intake department.

In one embodiment, one end of the air inlet communicated with the ventilation groove covers the ventilation groove, and the position of the air inlet enables all air in the ventilation groove to flow into the air inlet.

Above-mentioned technical scheme, through the one end with the air intake cover ventilation groove, the air in the ventilation groove can be through the air intake all by the suction fan in to improve temperature regulation's efficiency.

In one embodiment, the dissolution apparatus operating cabinet further comprises a humidity adjusting device, the humidity adjusting device is disposed in the base, and the humidity adjusting device is communicated with the fan.

Above-mentioned technical scheme is linked together humidity control device and fan through setting up humidity control device, and the holding chamber can simulate the internal environment humidity of human body to improve the accuracy that dissolves out the appearance and carry out the medicine and dissolve out the experiment.

In one embodiment, the dissolution apparatus operating cabinet further comprises a filtering device, and the filtering device is communicated with the fan and the air inlet pipe.

Above-mentioned technical scheme, through setting up filter equipment, at the in-process that temperature regulation apparatus carried out air cycle cooling, volatile toxic component can be absorbed through filter equipment, prevents that in the medicine dissolution process, the toxic component in the air accounts for more and more than producing the overflow.

In one embodiment, the door plate and the side plate are made of sound insulation materials.

Above-mentioned technical scheme, dissolve out the appearance and need carry out mechanical stirring at the medicine dissolving in-process, can produce a large amount of noises from this, through setting up curb plate and door plant into sound-proof material, can effectively reduce the noise that produces in the appearance operation process of dissolving out.

In one embodiment, the door panel is made of a transparent material.

Above-mentioned technical scheme sets up to transparent material through setting up the door plant, and the experimenter can be in the dissolution situation of the in-process observation medicine of dissolving out, and the experimenter of being convenient for masters and takes notes the experiment progress.

In one embodiment, the temperature adjusting device further comprises an installation box, the fan and the air inlet pipe are arranged in the installation box, and the air exhaust pipe is partially arranged in the installation box in a penetrating mode.

Above-mentioned technical scheme sets up in the installing box after integrating exhaust fan, air-supply line and exhaust pipe, can simplify temperature regulation apparatus, the nimble installation of the temperature regulation apparatus of being convenient for.

In summary, the dissolution instrument operating cabinet at least comprises one of the following beneficial technical effects:

1. the dissolution environment of the drug is simulated by the temperature regulation means and the control means, and is maintained at, for example, room temperature or the temperature in the human body. In order to prevent volatilization of part of toxic components in the dissolving process, the dissolving-out instrument is placed in a closed box body, and meanwhile, the air inlet pipe and the air outlet are arranged in the accommodating cavity, so that the self-circulation of air is realized and the temperature is increased and decreased on the premise that the gas in the box body is not diffused outwards, and the constant environment temperature required by the dissolution of the medicine is kept.

2. Through setting up humidity control device, be linked together humidity control device and fan, the environmental humidity in the human body can be simulated to the holding chamber to improve the accuracy that dissolves out the appearance and carry out medicine and dissolve out the experiment

3. Through setting up filter equipment, at the in-process that temperature regulation apparatus carried out air cycle cooling, volatile toxic component can be absorbed through filter equipment, prevents that in the medicine dissolving process, the toxic component in the air accounts for more and more greatly and produces the overflow.

4. Dissolve out the appearance and need carry out mechanical stirring at the medicine dissolving in-process, can produce a large amount of noises from this, through setting up curb plate and door plant into sound-proof material, can effectively reduce the noise that produces in the appearance operation process of dissolving out.

5. Set up in the installation box after integrating exhaust fan, air-supply line and exhaust pipe, can simplify temperature regulation apparatus, temperature regulation apparatus's of being convenient for nimble installation.

Drawings

FIG. 1 is a schematic view of a first perspective of an operating cabinet of a dissolution apparatus according to an embodiment of the present disclosure;

FIG. 2 is a schematic diagram showing a second perspective view of an operating cabinet of a dissolution apparatus according to an embodiment of the present application.

Description of reference numerals:

100. a base; 200. a box body; 210. a side plate; 220. a door panel; 230. an accommodating cavity; 240. a ventilation slot; 241. a support bar; 300. a temperature adjustment device; 310. an air inlet; 320. an air inlet pipe; 330. a fan; 340. an exhaust duct; 350. an air outlet; 360; installing a box; 400. a control device; 410. a controller; 420. a temperature collector; 500. a humidity adjusting device; 600. and (4) a filtering device.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present application more comprehensible, embodiments accompanying the present application are described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application. This application is capable of embodiments in many different forms than those described herein and that modifications may be made by one skilled in the art without departing from the spirit and scope of the application and it is therefore not intended to be limited to the specific embodiments disclosed below.

Referring to fig. 1, fig. 1 is a schematic structural diagram illustrating a first view angle of a dissolution apparatus operating cabinet according to an embodiment of the present application, and the dissolution apparatus operating cabinet according to the embodiment of the present application includes a base 100, a box 200, a temperature adjusting device 300, and a control device 400. The box 200 is disposed on top of the base 100, and the box 200 has a receiving chamber 230 for placing a dissolution apparatus (not shown). The accommodating chamber 230 is a closed environment to prevent toxic components generated when the drug in the dissolution apparatus is dissolved from being volatilized to the outside. The temperature adjusting device 300 comprises a fan 330, an air inlet pipe 320 and an air outlet pipe 340, the air inlet pipe 320 and the air outlet pipe 340 are both communicated with the accommodating cavity 230, the fan 330 is used for heating and cooling the air sucked by the air inlet pipe 320 and then discharging the air into the accommodating cavity 230 through the air outlet pipe 340, so that the fan 330 is controlled by the control device 400 on the premise that the air is not discharged outwards, the temperature in the accommodating cavity 230 is kept constant, and the temperature of the medicine dissolved in different environments can be better simulated.

The box 200 includes a plurality of side plates 210 and a door plate 220, and the side plates 210 and the door plate 220 surround to form an accommodating chamber 230. The side plate 210 is used for isolating air circulation inside and outside the accommodating cavity 230, and the door plate 220 can be opened and closed to realize placement of the dissolution instrument and/or the medicine. A ventilation groove 240 is further disposed on one side plate 210 of the box 200 in contact with the base 100 for communicating the accommodating chamber 230 with the blower 330, so as to achieve the ventilation and cooling functions of the dissolution apparatus operating cabinet. Specifically, the side plates 210 are provided as a soundproof material, preferably, a double-layer soundproof structure in which an inner layer is provided as soundproof cotton and an outer layer is provided as a fiberboard, so that the cabinet 200 has a good soundproof effect while ensuring its structural strength. Sealant is filled between the side plate 210 and the door plate 220, so that when the door plate 220 is closed, the accommodating chamber 230 has good air tightness, and prevents air from diffusing to the outside through gaps. The door panel 220 is made of a transparent material with a sound insulation effect, so that an experimenter can observe the dissolution condition of the medicine in the dissolution process, and the experimenter can master and record the experiment progress conveniently.

In the present embodiment, the box 200 is a rectangular parallelepiped, and the ventilation slot 240 is disposed on the bottom plate of the box 200. The inside of the side plate 210 is also provided with a corrosion-resistant and moisture-proof coating to prevent volatile components in the drug solution from attacking the side plate 210. The door plate 220 adopts a double-layer sound insulation glass structure, and the side plate 210 made of sound insulation materials is matched, so that the noise generated when the dissolution instrument works can be reduced to be below 65 decibels.

In some embodiments, a power socket and a power switch are also disposed on the side panel 210, and the power socket is electrically connected to the dissolution apparatus for providing power to the dissolution apparatus. The power switch is used for controlling the on-off of the power socket, and the safety of the dissolution instrument operation cabinet is improved.

The ventilation groove 240 is provided on the bottom plate of the case 200, a plurality of support bars 241 are provided in the ventilation groove 240, and the plurality of support bars 241 form a support structure for placing the dissolution apparatus. By placing the dissolution apparatus in the ventilation groove 240, the air around the dissolution apparatus can have better fluidity, so as to reduce the error between the actual temperature of the dissolution apparatus and the rated temperature output by the fan 330, and improve the accuracy of the drug dissolution experiment. Specifically, in the present embodiment, the plurality of support rods 241 are arranged in parallel and at equal intervals along the horizontal direction to form a grid structure, so that the ventilation area of the ventilation groove 240 occupied by the support rods 241 is reduced, air can pass through the grid ventilation groove 240 more evenly, and the uniformity of temperature distribution is maintained. Meanwhile, the ventilation groove 240 of the grid structure can improve a relatively stable support structure to improve the installation stability of the dissolution instrument.

Referring to fig. 2, fig. 2 is a schematic structural diagram of a second view angle of the dissolution apparatus operating cabinet according to an embodiment of the present application. The temperature adjustment device 300 further includes an air inlet 310, and the air inlet 310 is communicated with the ventilation slot 240 and the air inlet pipe 320. Specifically, the air inlet 310 is configured to be funnel-shaped, and the pipe diameter of the air inlet 310 decreases gradually from one end of the air channel 240 to one end of the air inlet 310 communicated with the air inlet pipe 320, so that the pipe diameters of the two ends are different, a certain pressure difference is generated at the two ends of the air inlet 310, and the air exhaust effect at the air inlet 310 is improved. One end of the intake vent 310 communicating with the ventilation groove 240 completely covers the ventilation groove 240, and the air in the ventilation groove 240 can be completely drawn into the fan 330 through the intake vent 310, so as to improve the efficiency of temperature regulation.

In the embodiment, the ventilation slot 240 has a rectangular structure, the end of the intake vent 310 connected thereto is also configured as a rectangular structure, and the edge of the intake vent 310 is the same as the edge of the ventilation slot 240 in size and is overlapped in position.

The blower 330 is connected to the ventilation slot 240 through the air inlet pipe 320, and the blower 330 is used for driving air to flow from the ventilation slot 240 to the air outlet 350 along the air inlet pipe 320, the blower 330 and the exhaust pipe 340. Specifically, the blower 330 generates a negative pressure at the intake port 310 to allow air to flow from the ventilation slot 240 along the intake pipe into the blower 330, while generating a positive pressure to exhaust air to the outlet port to allow air to flow from the exhaust pipe to the outlet port.

The control device 400 includes a controller 410, and the controller 410 is communicatively connected to the fan 330 for controlling the operating power of the fan 330. The control device 400 further includes a temperature collector 420, and the temperature collector 420 is used for detecting the temperature in the accommodating chamber 230. In particular, in the present embodiment, the controller 410 includes a control panel disposed on the side plate 210, and the temperature detector includes an electronic display screen disposed on the side plate 210.

In some embodiments, the dissolution apparatus operating cabinet further comprises a filtering device 600, the filtering device 600 is disposed in the base 100, the filtering device 600 is communicated between the blower 330 and the air inlet pipe 320, and by disposing the filtering device 600, during the air circulation cooling process of the temperature adjusting device 300, volatile toxic components can be absorbed through the filtering device 600, so as to prevent the toxic components in the air from overflowing more and more in proportion during the drug dissolution process. Specifically, the filtering apparatus 600 includes a filter screen on which an adsorbent for adsorbing toxic components is disposed. In this embodiment, the adsorbent is preferably activated carbon.

It should be noted that those skilled in the art can select an adsorbent having a high adsorption effect on a part of the components of the drug to be dissolved, adaptively according to the difference in the dissolved drug.

In some embodiments, the dissolution apparatus operating cabinet further includes a humidity adjusting device 500, the humidity adjusting device 500 is disposed in the base 100, and the humidity adjusting device 500 is communicated with the blower 330 to remove or add moisture to the flowing air, so as to adjust the humidity of the accommodating cavity 230, so that the accommodating cavity 230 can simulate the environmental humidity in the human body, thereby improving the accuracy of the dissolution apparatus in performing the drug dissolution experiment.

In some embodiments, the temperature adjustment device 300 further includes a mounting box 360, and the blower 330, the air inlet pipe 320 and the air outlet pipe 340 are disposed in the body 200 of the mounting box 360, so that the components of the temperature adjustment device 300 are integrated to protect the blower 330 and the pipeline.

Further, the humidity control device 500 and the filtering device 600 are also disposed in the installation box 360 to integrate each functional module in the installation box 360, so as to facilitate the installation of the temperature control device 300, the humidity control device 500 and the filtering device 600.

One part of the exhaust pipe is inserted into the susceptor 100, and the other part of the exhaust pipe is disposed in the accommodating cavity 230 of the case 200. One end of the exhaust pipe is communicated with the fan 330, the other end is provided with an air outlet 350, and the air outlet 350 is arranged on one side of the accommodating cavity 230 far away from the ventilation groove 240, so that the overall temperature distribution in the accommodating cavity 230 is optimized, and the temperature adjusting effect is improved. Specifically, the height of the air outlet 350 in the accommodating cavity 230 is higher than that of the dissolution apparatus, so as to avoid that the air flows out of the air outlet 350 and interferes with the dissolution process of the drug in the dissolution apparatus, thereby affecting the accuracy of the experimental result.

The implementation principle of the dissolution instrument operation cabinet is as follows: the dissolution instrument is placed in a closed box body 200 to carry out a drug dissolution experiment so as to prevent toxic components in the drug from diffusing to the outside to cause harm after volatilization. Through temperature regulation apparatus 300, humidity control device 500, dissolve out the dissolution environment that the appearance operation cabinet can simulate the medicine, also can prevent that the medicine from constantly accumulating at the dissolution in-process heat to improve the accuracy of experimental result. The dissolution instrument is placed in the closed box 200, and the air inlet pipe 320 and the air outlet 350 are both arranged in the accommodating cavity 230, so that the air is self-circulated and the temperature is raised and lowered on the premise that the gas in the box 200 is not diffused outwards, and the constant ambient temperature required by the dissolution of the medicine is kept.

In the description of the present application, it is to be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the present application and for simplicity in description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the present application.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present application, "plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.

In this application, unless expressly stated or limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can include, for example, fixed connections, removable connections, or integral parts; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art as appropriate.

In this application, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through intervening media. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the claims. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, and these are all within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (10)

1. A dissolution apparatus operating cabinet, comprising: a base (100);

the box body (200) is arranged at the top of the base (100), the box body (200) comprises a plurality of side plates (210) and door plates (220), the side plates (210) and the door plates (220) surround to form accommodating cavities (230), and ventilation grooves (240) are formed in the side plates (210) connected with the base (100);

the temperature adjusting device (300) comprises a fan (330), an air inlet pipe (320), an air outlet pipe (340) and an air outlet (350), wherein the fan (330) is arranged in the base (100), the air inlet pipe (320) and the air outlet pipe (340) penetrate through the base (100), the air outlet (350) is arranged on one side, far away from the ventilation groove (240), in the accommodating cavity (230), the air inlet pipe (320) is communicated with the fan (330) and the ventilation groove (240), the air outlet pipe (340) is communicated with the fan (330) and the air outlet (350), and the fan (330) is used for driving air to flow from the ventilation groove (240) to the air outlet (350) along the air inlet pipe (320), the fan (330) and the air outlet pipe (340); and

a control device (400) comprising a controller (410), the controller (410) being communicatively connected to the fan (330), the controller (410) being capable of controlling an operating power of the fan (330).

2. The dissolution instrument operating cabinet according to claim 1, wherein a support rod (241) is disposed in the ventilation groove (240), two ends of the support rod (241) are fixedly connected to an inner wall of the ventilation groove (240), and the dissolution instrument is disposed on the support rod (241).

3. The dissolution apparatus operating cabinet according to claim 2, wherein the plurality of support rods (241) are horizontally disposed in the ventilation slot (240) in parallel and at equal intervals.

4. The dissolution apparatus operating cabinet according to claim 1, wherein the temperature adjusting device (300) further comprises an air inlet (310), the air inlet (310) is connected to the ventilating slot (240) and the air inlet pipe (320), and a diameter of an end of the air inlet (310) connected to the ventilating slot (240) is larger than a diameter of an end of the air inlet (310) connected to the air inlet pipe (320).

5. The dissolution meter operating cabinet according to claim 4, wherein the end of the air inlet (310) communicating with the ventilation slot (240) covers the ventilation slot (240) and is positioned to allow air in the ventilation slot (240) to flow into the air inlet (310).

6. The dissolution apparatus operating cabinet according to claim 1, further comprising a humidity adjusting device (500), wherein the humidity adjusting device (500) is disposed in the base (100), and the humidity adjusting device (500) is communicated with the blower (330).

7. The dissolution apparatus operating cabinet according to claim 1, further comprising a filtering device (600), wherein the filtering device (600) is in communication with the blower (330) and the air inlet pipe (320).

8. The dissolution apparatus operating cabinet according to claim 1, wherein the door panels (220) and the side panels (210) are made of sound insulating material.

9. The dissolution apparatus operating cabinet according to claim 1, wherein the door panel (220) is made of a transparent material.

10. The dissolution apparatus operating cabinet according to claim 1, wherein the temperature adjusting device (300) further comprises an installation box (360), the blower (330) and the air inlet pipe (320) are disposed in the installation box (360), and the exhaust pipe (340) is partially disposed through the installation box (360).

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