CN217940535U

CN217940535U - High-speed centrifuge is used in antibody production preparation convenient to it is clean

Info

Publication number: CN217940535U
Application number: CN202222360679.8U
Authority: CN
Inventors: 陈旭华; 汪渊; 谌敦华
Original assignee: Shanghai Cymbal Poetry Biotechnology Co ltd
Current assignee: Shanghai Cymbal Poetry Biotechnology Co ltd
Priority date: 2022-09-06
Filing date: 2022-09-06
Publication date: 2022-12-02
Anticipated expiration: 2032-09-06

Abstract

The utility model relates to a high-speed centrifuge for antibody production and preparation convenient to clean, which comprises a shell and an electric telescopic rod, wherein the electric telescopic rod is fixed outside the shell in a bilateral symmetry manner, the output end of the electric telescopic rod is fixed on the lower end face of a movable plate, a fixed plate is fixed on the movable plate, a driving motor is fixed on the fixed plate, a first bevel gear is fixed on the output shaft of the driving motor and is arranged above the movable plate, a driving gear is also fixed on the output shaft of the driving motor and is arranged below the movable plate, and an equiangular bearing on the lower end face above the movable plate is connected with a cleaning roller; the bearing is connected to the upper end face of the movable plate, the movable plate is penetrated through by the vertical plate, the vertical plate and the movable plate can slide, a brush plate is fixed on the outer side of the vertical plate, and a spray head is fixed on the outer side of the vertical plate; the utility model discloses can realize the comprehensive cleaning action to the shell inner wall to and the clearance to the impurity of standing groove inner wall, thereby guarantee the clearance effect to centrifuge.

Description

High-speed centrifuge is used in antibody production preparation convenient to it is clean

Technical Field

The utility model relates to a high speed centrifuge technical field specifically is a high speed centrifuge is used in antibody production preparation convenient to it is clean.

Background

In the production process of the antibody, the separation effect on the solution is often required to be realized through a high-speed centrifuge, so that the liquid with different components can be conveniently extracted, certain impurities are easily bonded in the inner wall of the shell of the high-speed centrifuge after the high-speed centrifuge is used, the impurities need to be cleaned, and the corrosion damage to the inner wall of the shell caused by the bonding of the impurities is avoided, the existing cleanable centrifuge is a conveniently cleaned biological centrifuge such as a CN208390254U (publication No. CN 208390254U), and comprises a centrifuge component and a transmission component, wherein the centrifuge component comprises a centrifuge, a feed pipe, a discharge pipe, a sealing cover, a heater, a centrifuge and a display screen, the sealing cover is arranged at the top of the centrifuge, the sealing cover is rotatably connected with the centrifuge, 8230, the rotating shaft is in transmission connection with the motor through a belt, and the motor is electrically connected with an external power supply;

above-mentioned current centrifuge that can clean still has certain defect when using, current centrifuge mainly realizes the clearance effect through water injection cooperation self rotation, and in centrifugal process, because the effect of centrifugal force, impurity and shell inner wall bond is tighter, simple washing is difficult to guarantee that the clearance is complete, thereby lead to the clearance effect relatively poor, and in centrifugal process, certain impurity also exists in the test tube inslot, need clear up through artifical manual, it is comparatively troublesome, so need improve in order to satisfy the in-service use demand to above-mentioned problem.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a high-speed centrifuge is used in antibody production preparation convenient to it relatively poor and the comparatively trouble problem of manual cleaning to propose the clearance effect in solving above-mentioned background art.

In order to achieve the purpose, the high-speed centrifuge convenient for cleaning antibody production and preparation comprises a shell, wherein a centrifugal motor is fixed in the shell, a placing box is fixed at the tail end of an output shaft of the centrifugal motor, placing grooves for placing test tubes are formed in the placing box at equal angles, and drainage valve ports are symmetrically fixed on the left side and the right side of the shell; further comprising: the electric telescopic rods are fixed on the outer side of the shell in a bilateral symmetry mode, the output ends of the electric telescopic rods are fixed on the lower end face of the movable plate, the fixed plate is fixed on the movable plate, the driving motor is fixed on the fixed plate, a first bevel gear is fixed on an output shaft of the driving motor and arranged above the movable plate, a driving gear is further fixed on the output shaft of the driving motor and arranged below the movable plate, and the lower end face above the movable plate is connected with a cleaning roller through an equal-angle bearing; rotation axis, bearing connection are in the fly leaf up end, and the fly leaf is run through by the riser to can slide between riser and the fly leaf, the riser outside is fixed with the brush board simultaneously, the riser outside still is fixed with the shower nozzle, and the shower nozzle passes through pipe and pump machine and water tank interconnect and realizes the water source transport effect.

Further, the cleaning rollers are distributed in a one-to-one correspondence mode with the placing grooves, the cleaning rollers are nested in the placing grooves and can slide, and the cleaning effect on sundries in the placing grooves can be achieved through the cleaning rollers, so that manual cleaning is avoided, and the operation is convenient and simple.

Further, still be fixed with driven gear on the cleaning roller, and driven gear and driving gear meshing realize the transmission effect, when the driving gear rotated, through the meshing transmission effect between driving gear and the driven gear, can provide basic effort for the rotation of cleaning roller.

Furthermore, a disc, a convex shaft and a second bevel gear are arranged on the rotating shaft; the disc is fixed at the outer side end of the rotating shaft, and the diameter of the disc is smaller than the length of the transverse plate; the convex shaft is fixed on the disc; the second bevel gear is fixed at the inner side end of the rotating shaft, the second bevel gear is meshed with the first bevel gear to realize transmission, basic guarantee can be provided for rotation of the rotating shaft, the disc and the protruding shaft through the meshing transmission between the first bevel gear and the second bevel gear, and normal operation of the device can be guaranteed through limiting the diameter of the disc.

Furthermore, the transverse plate is fixed on the upper end face of the vertical plate, the slidable convex shaft is connected to the groove in the transverse plate in an embedded mode, and when the convex shaft rotates, basic acting force can be provided for up-and-down movement of the vertical plate through the sliding effect between the convex shaft and the groove in the transverse plate.

Further, the brush board is equidistant distribution on the riser, and the brush board is provided with three groups on the riser to the brush board can slide from top to bottom with the contact of shell inner wall, when the riser removed, drives the brush board simultaneously and reciprocates in step, through the contact sliding effect of brush board and shell inner wall, can realize the clearance to shell inner wall impurity, thereby guarantees clean effect.

Compared with the prior art, the utility model, following beneficial effect has:

1. the utility model is provided with the brush plate, when cleaning the inner wall of the shell, the transverse plate and the brush plate can move up and down orderly through the rotation of the convex shaft and the sliding action between the convex shaft and the transverse plate, and the comprehensive cleaning action of the inner wall of the shell can be realized through the contact sliding action of a plurality of groups of brush plates and the inner wall of the shell, thereby ensuring the cleaning effect;

2. the cleaning roller is arranged in the utility model, and is nested in the placing groove, and then the cleaning roller can rotate by matching with the meshing transmission action between the driven gear and the driving gear, thereby realizing the cleaning action on the inner wall of the placing groove, avoiding manual cleaning, and being more convenient and simpler;

to sum up, the utility model discloses a lifting cleaning structure of linkage can realize the comprehensive cleaning effect to the shell inner wall, and cleaning mechanism during the rotation of cooperation linkage can realize the clearance to the impurity of standing groove inner wall, and is convenient simple to guarantee the clearance effect to centrifuge, and whole device has advantages such as simple structure and convenient operation.

Drawings

FIG. 1 is a schematic view of the front cross-sectional structure of the housing of the present invention;

FIG. 2 is a schematic view of the front sectional structure of the movable plate of the present invention;

FIG. 3 is a schematic view of the three-dimensional structure of the cleaning roller of the present invention;

fig. 4 is a schematic view of the three-dimensional structure of the rotating shaft of the present invention;

fig. 5 is a schematic view of the three-dimensional structure of the brush plate of the present invention.

In the figure: 1. a housing; 2. a centrifugal motor; 3. placing the box; 4. a placement groove; 5. a drain valve port; 6. an electric telescopic rod; 7. a movable plate; 8. a fixing plate; 9. a drive motor; 10. a first bevel gear; 11. a driving gear; 12. a cleaning roller; 1201. a driven gear; 13. a rotating shaft; 1301. a disc; 1302. a protruding shaft; 1303. a second bevel gear; 14. a vertical plate; 1401. a transverse plate; 15. a brush plate; 16. a spray head; 17. a water tank.

Detailed Description

The invention is further described below with reference to the accompanying drawings:

referring to the attached drawings 1-5, the utility model provides a high-speed centrifuge for producing and preparing antibodies, which is convenient to clean and comprises a shell 1, wherein a centrifugal motor 2 is fixed in the shell 1, a placing box 3 is fixed at the tail end of an output shaft of the centrifugal motor 2, a placing groove 4 is formed on the placing box 3 at an equal angle for placing a test tube, and drainage valve ports 5 are symmetrically fixed on the left side and the right side of the shell 1; further comprising: the electric telescopic rods 6 are fixed on the outer side of the shell 1 in a bilateral symmetry mode, the output ends of the electric telescopic rods 6 are fixed on the lower end face of the movable plate 7, the fixed plate 8 is fixed on the movable plate 7, the driving motor 9 is fixed on the fixed plate 8, a first bevel gear 10 is fixed on an output shaft of the driving motor 9, the first bevel gear 10 is arranged above the movable plate 7, a driving gear 11 is further fixed on the output shaft of the driving motor 9, the driving gear 11 is arranged below the movable plate 7, and the lower end face above the movable plate 7 is connected with a cleaning roller 12 through an equiangular bearing; the rotating shaft 13 and the bearing are connected to the upper end face of the movable plate 7, the movable plate 7 is penetrated through by the vertical plate 14, the vertical plate 14 and the movable plate 7 can slide, a brush plate 15 is fixed to the outer side of the vertical plate 14, a spray head 16 is further fixed to the outer side of the vertical plate 14, and the spray head 16 is connected with a water tank 17 through a guide pipe and a pump to achieve a water source conveying effect.

The cleaning rollers 12 are distributed in one-to-one correspondence with the placing grooves 4, and the cleaning rollers 12 are nested in the placing grooves 4 and can slide; a driven gear 1201 is further fixed on the cleaning roller 12, and the driven gear 1201 is meshed with the driving gear 11 to achieve a transmission effect.

When the high-speed centrifuge convenient for cleaning antibody production and preparation is used, the whole device is placed, power is supplied to the whole device through an external power supply, when the shell 1 is cleaned, as shown in fig. 1, the movable plate 7 is driven to move downwards by controlling the electric telescopic rod 6 to contract until the movable plate moves to a limit position, the cleaning roller 12 is embedded in the placing groove 4 at the moment, cleaning liquid in the water tank 17 is injected into the spray head 16 through the water pump and the water guide pipe to be sprayed, the water discharging valve port 5 is closed at the moment, so that a water injection effect is realized, after the cleaning liquid is completely added, the first bevel gear 10 and the driving gear 11 are driven to rotate under the action of the driving motor 9 by starting the driving motor 9, the cleaning roller 12 can be stressed to rotate under the action of the driven gear 1201 by matching with the meshing transmission effect between the driving gear 11 and the driven gear 1201, the cleaning roller 12 can clean the inner wall of the placing groove 4, and the operation is convenient and simple.

The rotating shaft 13 is also provided with a circular disc 1301, a convex shaft 1302 and a second bevel gear 1303; a disc 1301 fixed at the outer end of the rotating shaft 13, wherein the diameter of the disc 1301 is smaller than the length of the transverse plate 1401; a protruding shaft 1302 fixed to the disc 1301; the second bevel gear 1303 is fixed at the inner side end of the rotating shaft 13, and the second bevel gear 1303 is meshed with the first bevel gear 10 to realize transmission; a transverse plate 1401 is fixed on the upper end surface of the vertical plate 14, and a slidable convex shaft 1302 is nested and connected in a groove on the transverse plate 1401; the brush boards 15 are distributed on the vertical board 14 at equal intervals, three groups of brush boards 15 are arranged on the vertical board 14, and the brush boards 15 can slide up and down by contacting with the inner wall of the shell 1.

When the first bevel gear 10 rotates, the rotating shaft 13 can rotate under stress through the meshing transmission effect between the first bevel gear 10 and the second bevel gear 1303, so as to drive the disc 1301 and the protruding shaft 1302 to rotate, the protruding shaft 1302 and the transverse plate 1401 are matched with the sliding effect between the slots in the protruding shaft 1302 and the transverse plate 1401, the transverse plate 1401 is forced to move up and down in order, so as to drive the vertical plate 14 to move up and down in order, the vertical plate 14 and the movable plate 7 are matched with the sliding effect between the vertical plate 14 and the movable plate 7, the moving stability of the vertical plate 14 can be ensured, the vertical plate 14 is driven to move up and down in order when moving, the brush plates 15 are driven to move up and down in order at the same time, through the contact sliding effect of the multiple groups of the brush plates 15 and the inner wall of the shell 1, the cleaning of the inner wall of the shell 1 can be realized, after the cleaning is completed, the sewage can be discharged by opening the drainage valve port 5.

The utility model discloses a theory of operation does: as shown in fig. 1-5, when the high-speed centrifuge for antibody production and preparation convenient to clean is used, as shown in fig. 1, the movable plate 7 is driven to move downwards by controlling the electric telescopic rod 6 to contract until the movable plate moves to a limit position, at the moment, the cleaning roller 12 is nested in the placing groove 4, cleaning liquid is sprayed by the spray head 16 to realize a water injection effect, after the water injection is completed, the driving motor 9 drives the first bevel gear 10 and the driving gear 11 to rotate, the cleaning roller 12 can be forced to rotate by matching with the meshing transmission effect between the driving gear 11 and the driven gear 1201, so that the cleaning effect on the inner wall of the placing groove 4 is realized, then the rotating shaft 13, the disc 1301 and the convex shaft 1302 can rotate by matching with the meshing transmission effect between the convex shaft 1302 and the slot on the transverse plate 1401, the vertical plate 14 and the brush plate 15 can be orderly rotated, the contact sliding effect between the plurality of groups of the brush plates 15 and the inner wall of the shell 1 can realize the cleaning of the inner wall of the shell 1, the inner wall of the shell 1 is ensured, after the cleaning, the cleaning is completed, the sewage can be discharged by opening the high-speed centrifuge, and the principle of the high-speed centrifuge for producing and the clean can be convenient to discharge sewage.

The present invention is not limited by the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be equivalent replacement modes, and are all included in the protection scope of the present invention.

Claims

1. A high-speed centrifuge convenient for cleaning and used for antibody production and preparation comprises a shell (1), wherein a centrifugal motor (2) is fixed in the shell (1), a placing box (3) is fixed at the tail end of an output shaft of the centrifugal motor (2), placing grooves (4) for placing test tubes are formed in the placing box (3) at equal angles, and drainage valve ports (5) are symmetrically fixed on the left side and the right side of the shell (1); it is characterized by also comprising:

the electric telescopic rods (6) are fixed on the outer side of the shell (1) in a bilateral symmetry mode, the output ends of the electric telescopic rods (6) are fixed on the lower end face of the movable plate (7), the movable plate (7) is fixedly provided with a fixed plate (8), meanwhile, the fixed plate (8) is fixedly provided with a driving motor (9), an output shaft of the driving motor (9) is fixedly provided with a first bevel gear (10), the first bevel gear (10) is arranged above the movable plate (7), an output shaft of the driving motor (9) is also fixedly provided with a driving gear (11), the driving gear (11) is arranged below the movable plate (7), and an equal-angle bearing is connected to the lower end face above the movable plate (7) and is connected with a cleaning roller (12);

rotation axis (13), bearing connection are in fly leaf (7) up end, and fly leaf (7) are run through by riser (14) to can slide between riser (14) and fly leaf (7), riser (14) outside is fixed with brush board (15) simultaneously, riser (14) outside still is fixed with shower nozzle (16), and shower nozzle (16) realize the water source transport effect through pipe and pump machine and water tank (17) interconnect.

2. A high-speed centrifuge for antibody production preparation facilitating cleaning according to claim 1, characterized in that: the cleaning rollers (12) and the placing grooves (4) are distributed in a one-to-one correspondence mode, and the cleaning rollers (12) are nested in the placing grooves (4) and can slide.

3. A high-speed centrifuge for antibody production preparation facilitating cleaning according to claim 1, characterized in that: a driven gear (1201) is further fixed on the cleaning roller (12), and the driven gear (1201) is meshed with the driving gear (11) to achieve a transmission effect.

4. A high-speed centrifuge for antibody production preparation facilitating cleaning according to claim 1, characterized in that: the rotating shaft (13) is also provided with a disc (1301), a convex shaft (1302) and a second bevel gear (1303);

a disc (1301) fixed at the outer end of the rotating shaft (13), wherein the diameter of the disc (1301) is smaller than the length of the transverse plate (1401);

a protruding shaft (1302) fixed on the disc (1301);

and the second bevel gear (1303) is fixed at the inner side end of the rotating shaft (13), and the second bevel gear (1303) is meshed with the first bevel gear (10) to realize transmission effect.

5. A high-speed centrifuge for production preparation of antibodies facilitating cleaning according to claim 4, wherein: a transverse plate (1401) is fixed on the upper end face of the vertical plate (14), and a sliding convex shaft (1302) is connected in a groove in the transverse plate (1401) in a nested mode.

6. A high-speed centrifuge for antibody production preparation facilitating cleaning according to claim 1, characterized in that: brush board (15) are equidistant distribution on riser (14), and brush board (15) are provided with three groups on riser (14) to brush board (15) and shell (1) inner wall contact can slide from top to bottom.