CN217868689U

CN217868689U - Antibody and antigen are with purification equipment

Info

Publication number: CN217868689U
Application number: CN202221294402.3U
Authority: CN
Inventors: 刘玲; 周道亮
Original assignee: Hunan Ruiqin Biotechnology Co ltd
Current assignee: Hunan Ruiqin Biotechnology Co ltd
Priority date: 2022-05-27
Filing date: 2022-05-27
Publication date: 2022-11-22
Anticipated expiration: 2032-05-27

Abstract

The utility model discloses a purification equipment for antibody and antigen relates to purification equipment technical field, the following scheme is proposed at present, the on-line screen storage device comprises a base, the top of base is rotated and is installed the backup pad, the support column is installed to top one side of backup pad, be connected with the lifter plate through elevating system on the support column, the jack has been seted up on the lifter plate, the centre gripping subassembly is installed on the top of jack, the loading board is installed on the top of backup pad, the below that lies in the jack on the loading board is provided with corresponding slot, there is first ultraviolet lamp on the top of lifter plate through the support mounting, second ultraviolet lamp is installed to the bottom avris of lifter plate, the centre gripping subassembly includes the first clamp splice of fixed mounting in the jack top, and fixed plate. The utility model discloses in, can shine through first ultraviolet lamp and disinfect to the top of lifter plate, can shine through second ultraviolet lamp and disinfect to the top of loading board, the contaminated risk of affinity post of avoiding of great degree and eluant receiver tube.

Description

Antibody and antigen are with purification equipment

Technical Field

The utility model relates to a purification equipment technical field especially relates to an antibody and antigen are with purification equipment.

Background

Purification of antigens and antibodies requires the use of affinity purification columns, which are typically fixed in fixed arms on an iron stand, to which a sample is added when an experiment is to be performed, and under which the flow-through or eluate is collected. Generally, the fixed affinity column is not easy to replace, and bacteria are easy to breed on a table top after long-term use, so that the purification equipment for the antibody and the antigen is provided.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving the defects in the prior art and providing a purifying device for antibodies and antigens.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

the utility model provides a purification equipment for antibody and antigen, includes the base, the top of base is rotated and is installed the backup pad, the support column is installed to top one side of backup pad, be connected with the lifter plate through elevating system on the support column, the jack has been seted up on the lifter plate, the centre gripping subassembly is installed on the top of jack, the loading board is installed on the top of backup pad, the below that lies in the jack on the loading board is provided with corresponding slot, there is first ultraviolet lamp on the top of lifter plate through the support mounting, second ultraviolet lamp is installed to the bottom avris of lifter plate.

Preferably, the clamping component comprises a first clamping block fixedly mounted above the jack and a fixing plate, the middle of the fixing plate is screwed with a locking bolt, one end of the locking bolt is rotatably connected with a second clamping block through a bearing, and the first clamping block and the second clamping block are respectively located on two sides of the jack.

Preferably, elevating system installs the threaded rod through the bearing including seting up the mounting groove on the support column in the mounting groove, the spiro union has the lifter on the threaded rod, servo motor is installed on the top of support column, and servo motor's bottom is run through to be connected with the top transmission of threaded rod in the mounting groove, one side of lifter is connected with the one end of lifter.

Preferably, the top end of the base is provided with a rotary damper, the bottom end of the supporting plate is provided with a connecting rod, and the bottom of the connecting rod is connected with the rotary damper.

Preferably, the support comprises a fixed rod installed on the lifting plate, a cross beam is installed at the top end of the fixed rod, and the first ultraviolet lamp is arranged at the bottom end of the cross beam.

Preferably, the jacks are equidistantly arranged four, the bearing plate is provided with slots corresponding to the four jacks, and each jack is provided with a clamping assembly.

The utility model has the advantages that:

1. can shine through first ultraviolet lamp and disinfect to the top of lifter plate, can shine through second ultraviolet lamp and disinfect to the top of loading board, the contaminated risk of affinity post and eluant receiver tube of avoiding of great degree.

2. Move the locking bolt through twisting and drive the second clamp splice and remove, can utilize first clamp splice and second clamp splice to hold fixedly to the affinity post, rotate through servo motor drive threaded rod, can make the lifter drive lifter plate go up and down to rotatable backup pad angle regulation, facilitate the use, the practicality is better.

Drawings

Fig. 1 is a schematic diagram of a three-dimensional structure at a first viewing angle of a purification apparatus for antibodies and antigens according to the present invention.

Fig. 2 is a schematic diagram of a second perspective structure of an antibody and antigen purification apparatus provided by the present invention.

Fig. 3 is an enlarged schematic structural diagram of a point a in fig. 1 of the purification apparatus for antibody and antigen according to the present invention.

Fig. 4 is an enlarged schematic structural diagram of a purification apparatus for antibody and antigen in fig. 2.

In the figure: 1. a base; 2. a support plate; 3. a slot; 4. a servo motor; 5. mounting grooves; 6. a threaded rod; 7. a cross beam; 8. a fixing rod; 9. a lifting plate; 10. a support pillar; 11. a lifting rod; 12. a carrier plate; 13. a first ultraviolet lamp; 14. a connecting rod; 15. a jack; 16. a first clamping block; 17. a second clamping block; 18. locking the bolt; 19. a fixing plate; 20. a second ultraviolet lamp.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.

Embodiment 1, refer to fig. 1-4, a purification equipment for antibody and antigen, including base 1, base 1's top is rotated and is installed backup pad 2, support column 10 is installed to top one side of backup pad 2, be connected with lifter plate 9 through elevating system on the support column 10, equidistantly, four jacks 15 have been seted up on lifter plate 9, the centre gripping subassembly is installed on the top of every jack 15, insert the affinity column in jack 15, and utilize the centre gripping subassembly to fix the affinity column, loading board 12 is installed on the top of backup pad 2, be located the below of every jack 15 on loading board 12 and all be provided with corresponding slot 3, place the eluant receiver tube in the slot, adjust the height of adjustable affinity column through elevating system, the current that affinity column flowed down at last passes the eluant receiver tube and collects in the inside of eluant receiver tube, lifter plate 9's top is through the support mounting has first ultraviolet lamp 13, the support is including installing dead lever 8 on lifter plate 9, crossbeam 7 is installed on the top of dead lever 8, first ultraviolet lamp 13 is in the bottom of crossbeam 7, can carry out the top of sterilizing through ultraviolet lamp 20 irradiation to the ultraviolet lamp 20.

Embodiment 2, this embodiment is optimized on the basis of embodiment 1, and specifically includes:

the clamping assembly comprises a first clamping block 16 fixedly mounted above the jack 15 and a fixing plate 19, a locking bolt 18 is screwed in the middle of the fixing plate 19, one end of the locking bolt 18 is rotatably connected with a second clamping block 17 through a bearing, the first clamping block 16 and the second clamping block 17 are respectively located on two sides of the jack 15, the locking bolt 18 is screwed to drive the second clamping block 17 to move, and the first clamping block 16 and the second clamping block 17 can be used for clamping and fixing the affinity column.

Embodiment 3, this embodiment is optimized on the basis of embodiment 1, and specifically includes:

elevating system installs threaded rod 6 through the bearing including seting up mounting groove 5 on support column 10 in the mounting groove 5, the spiro union has lifter 11 on the threaded rod 6, servo motor 4 is installed on the top of support column 10, servo motor 4's bottom is run through to be connected with the top transmission of threaded rod 6 in the mounting groove 5, one side and the one end of lifter 11 of lifter plate 9 are connected, drive threaded rod 6 through servo motor 4 and rotate, can make lifter 11 drive lifter plate 9 go up and down.

Embodiment 4, this embodiment is optimized on the basis of embodiment 1, and specifically includes:

the rotary damper is installed on the top end of the base 1, the connecting rod 14 is installed at the bottom end of the supporting plate 2, the bottom of the connecting rod 14 is connected with the rotary damper, and the supporting plate 2 can be rotated to adjust the angle, so that the use is convenient.

Above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the design of the present invention, equivalent replacement or change should be covered within the protection scope of the present invention.

Claims

1. The utility model provides a purification equipment for antibody and antigen, includes base (1), its characterized in that, the top of base (1) is rotated and is installed backup pad (2), support column (10) are installed to top one side of backup pad (2), be connected with lifter plate (9) through elevating system on support column (10), jack (15) have been seted up on lifter plate (9), the centre gripping subassembly is installed on the top of jack (15), loading board (12) are installed on the top of backup pad (2), the below that lies in jack (15) on loading board (12) is provided with corresponding slot (3), there is first ultraviolet lamp (13) on the top of lifter plate (9) through the support mounting, second ultraviolet lamp (20) are installed to the bottom avris of lifter plate (9).

2. The antibody and antigen purification apparatus according to claim 1, wherein the clamping assembly comprises a first clamping block (16) fixedly mounted above the insertion hole (15) and a fixing plate (19), a locking bolt (18) is screwed in the middle of the fixing plate (19), one end of the locking bolt (18) is rotatably connected with a second clamping block (17) through a bearing, and the first clamping block (16) and the second clamping block (17) are respectively located on two sides of the insertion hole (15).

3. The antibody and antigen purification device according to claim 1, wherein the lifting mechanism comprises a mounting groove (5) formed in a support column (10), a threaded rod (6) is mounted in the mounting groove (5) through a bearing, a lifting rod (11) is screwed on the threaded rod (6), a servo motor (4) is mounted at the top end of the support column (10), the bottom end of the servo motor (4) penetrates into the mounting groove (5) to be in transmission connection with the top end of the threaded rod (6), and one side of the lifting plate (9) is connected with one end of the lifting rod (11).

4. The apparatus for purifying antibody and antigen according to claim 1, wherein a rotary damper is installed on the top end of the base (1), a connecting rod (14) is installed on the bottom end of the supporting plate (2), and the bottom of the connecting rod (14) is connected with the rotary damper.

5. The apparatus for purifying antibody and antigen as claimed in claim 1, wherein the support comprises a fixing rod (8) installed on the lifting plate (9), the top end of the fixing rod (8) is installed with a beam (7), and the first ultraviolet lamp (13) is arranged at the bottom end of the beam (7).

6. The antibody and antigen purification apparatus as claimed in claim 1, wherein the number of the insertion holes (15) is four, and the bearing plate (12) is provided with the insertion slots (3) corresponding to the four insertion holes (15), and each insertion hole (15) is provided with the clamping assembly.