CN217838986U

CN217838986U - Device for separating ultralow molecular hyaluronic acid tetrasaccharide and hexasaccharide

Info

Publication number: CN217838986U
Application number: CN202221645471.4U
Authority: CN
Inventors: 徐博
Original assignee: Nanjing Micro Structure Medicine Technology Co ltd
Current assignee: Nanjing Micro Structure Medicine Technology Co ltd
Priority date: 2022-06-28
Filing date: 2022-06-28
Publication date: 2022-11-18
Anticipated expiration: 2032-06-28

Abstract

The utility model discloses a device of separation ultra-low molecular hyaluronic acid tetrasaccharide, hexasaccharide relates to hyaluronic acid separation technical field. The utility model discloses a hydrolysis tank, hydrolysis tank's bottom fixedly connected with is evenly distributed's landing leg, and hydrolysis tank's top intercommunication has the inlet pipe, and hydrolysis tank's bottom intercommunication has the discharging pipe, is provided with the valve on the discharging pipe, and hydrolysis tank's top intercommunication has the outlet duct, and hydrolysis tank's inside is provided with accuse temperature subassembly. This hydrolysis device carries out the accuse temperature through setting up the accuse temperature subassembly, can effectively guarantee the inside temperature of jar of hydrolysising, has the advantage of stable accuse temperature.

Description

Device for separating ultralow molecular hyaluronic acid tetrasaccharide and hexasaccharide

Technical Field

The utility model relates to a hyaluronic acid separation technical field specifically is a device of separation ultra-low molecular hyaluronic acid tetrasaccharide, hexasaccharide.

Background

Hyaluronic acid, also known as hyaluronic acid, is an acidic mucopolysaccharide. The hyaluronic acid hydrolysis device is an important basic substance for skin tenderness, is a component of a human body, has a special water retention effect, is required to hydrolyze hyaluronic acid through hyaluronidase when separating hyaluronic acid tetrasaccharide and hexasaccharide, has an optimal temperature of 37 ℃ when hydrolyzing hyaluronic acid, and can be used as a hydrolysis device during hydrolysis, but still has the following defects in actual use:

the existing hydrolysis device can not well control the temperature, so that the difference between the actual temperature and the reaction suitable temperature is large, the reaction efficiency and the reaction result are influenced, the filter plate for treating waste gas during reaction is inconvenient to replace, the mounting and dismounting of workers are troublesome, and the labor intensity of the workers is increased.

In order to solve the problems, the device for separating the tetrasaccharide and the hexasaccharide of the ultra-low molecular hyaluronic acid is provided.

SUMMERY OF THE UTILITY MODEL

In order to solve the technical problem, the utility model provides a following technical scheme:

the utility model provides a device of separation ultra-low molecular hyaluronic acid tetrasaccharide, hexasaccharide, including the hydrolysis tank, the bottom fixedly connected with of hydrolysis tank is evenly distributed's landing leg, the top intercommunication of hydrolysis tank has the inlet pipe, the bottom intercommunication of hydrolysis tank has the discharging pipe, be provided with the valve on the discharging pipe, the top intercommunication of hydrolysis tank has the outlet duct, the inside of hydrolysis tank is provided with accuse temperature subassembly.

As a preferred technical scheme of the utility model, accuse temperature subassembly includes heating pipe, temperature sensor and heat dissipation fan, heating pipe fixed connection is in the inside of hydrolysis tank, temperature sensor fixed connection is in the inside of hydrolysis tank, heat dissipation fan fixed connection is in the inside of outlet duct, heat dissipation fan and heating pipe are all through temperature sensor and external switching power supply electric connection.

As a preferred technical scheme of the utility model, the inside of outlet duct is equipped with the filter, the card hole that is the symmetric distribution is seted up to the inside of outlet duct, the inside of filter is provided with the fixed subassembly that is the symmetric distribution, the filter is connected with the outlet duct through fixed subassembly.

As a preferred technical scheme of the utility model, fixed subassembly includes recess, kelly and spring, the outside at the filter is seted up to the recess, kelly swing joint is in the inside of recess, just the inside of kelly joint in the card hole, spring fixed connection is in the inside of recess, spring fixed connection is in the one end of kelly.

As a preferred technical scheme of the utility model, the inside intercommunication of recess has the spacing groove, the outside fixedly connected with limiting plate of kelly, the kelly passes through limiting plate and spacing groove sliding connection.

As a preferred technical scheme of the utility model, the guide way has been seted up to the inside of outlet duct, the outside fixedly connected with guide block of filter, the inside fixedly connected with magnet of guide way.

The utility model has the advantages that:

1. the heating pipe is started during reaction, the hydrolysis tank is heated, the temperature sensor can monitor the temperature inside the hydrolysis tank, if the temperature exceeds the set temperature, the temperature sensor sends an electric signal to an external switch to stop heating the heating pipe, and meanwhile, the filter plate is started to dissipate heat, so that the temperature inside the hydrolysis tank is reduced until the temperature of the hydrolysis tank returns to the set value and is closed, and the effect of stabilizing temperature control is achieved;

2. through the filter, can filter the produced waste gas of electrolysis, when changing the filter, press the inside of card hole with the kelly, at this moment the filter loses the restriction, then with the filter take out from the inside of outlet duct can, during the installation, press the inside to the recess with the kelly, the spring is compressed simultaneously, then aim at the guide way with the guide block, push the inside of outlet duct into the filter again, when the kelly meets with the card hole, the spring can promote the inside of kelly card income kelly, the installation of filter has just so been accomplished, can adsorb the guide block through magnet simultaneously, make the installation more firm like this, the effect of conveniently changing the filter has been reached from this.

Drawings

The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention. In the drawings:

FIG. 1 is a perspective view of the whole structure of the present invention;

FIG. 2 is a schematic sectional view of the structure of the hydrolysis tank of the present invention;

fig. 3 is an enlarged schematic view of the structure at a position a of the present invention;

fig. 4 is the schematic view of the partial sectional structure of the air outlet pipe of the present invention.

In the figure: 1. a hydrolysis tank; 2. a support leg; 3. a feed pipe; 4. a discharge pipe; 5. a valve; 6. an air outlet pipe; 7. a temperature control assembly; 701. heating a tube; 702. a temperature sensor; 703. a heat dissipation fan; 8. a filter plate; 9. a clamping hole; 10. a fixing assembly; 1001. a groove; 1002. a clamping rod; 1003. a spring; 11. a limiting groove; 12. a limiting plate; 13. a guide groove; 14. a guide block; 15. and a magnet.

Detailed Description

The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are presented herein only to illustrate and explain the present invention, and not to limit the present invention.

Please refer to fig. 1-3, the utility model discloses a separate ultra-low molecular hyaluronic acid tetrasaccharide, device of hexasaccharide, including hydrolysis tank 1, hydrolysis tank 1's bottom fixedly connected with is evenly distributed's landing leg 2, hydrolysis tank 1's top intercommunication has inlet pipe 3, hydrolysis tank 1's bottom intercommunication has discharging pipe 4, be provided with valve 5 on the discharging pipe 4, hydrolysis tank 1's top intercommunication has outlet duct 6, hydrolysis tank 1's inside is provided with accuse temperature subassembly 7, accuse temperature subassembly 7 includes heating pipe 701, thalposis 702 and heat dissipation fan 703, heating pipe 701 fixed connection is in hydrolysis tank 1's inside, thalposis 702 fixed connection is in hydrolysis tank 1's inside, heat dissipation fan 703 fixed connection is in the inside of outlet duct 6, heat dissipation fan 703 and heating pipe 701 are all through thalposis 702 and external switching power supply electric connection.

Can add hyaluronic acid and hyaluronidase to the inside of hydrolysis tank 1 through inlet pipe 3, carry out electrolytic reaction, can open discharging pipe 4 through valve 5 after the reaction and carry out the ejection of compact, heating pipe 701 starts during the reaction, heat hydrolysis tank 1, and can monitor hydrolysis tank 1 inside temperature through temperature sensor 702, if the temperature exceedes the settlement temperature, temperature sensor 702 sends out the signal of telecommunication and gives external switch this moment, make heating pipe 701 stop heating, 8 starts simultaneously and dispels the heat of filter, reduce hydrolysis tank 1 inside temperature, get back to the setting value and close until hydrolysis tank 1 temperature, the effect that can make things convenient for the accuse temperature has been reached from this.

As shown in fig. 2-4, the inside of outlet duct 6 is equipped with filter 8, the card hole 9 that is the symmetric distribution is seted up to the inside of outlet duct 6, the inside of filter 8 is provided with the fixed subassembly 10 that is the symmetric distribution, filter 8 is connected with outlet duct 6 through fixed subassembly 10, fixed subassembly 10 includes recess 1001, kelly 1002 and spring 1003, the outside at filter 8 is seted up to recess 1001, kelly 1002 swing joint is in the inside of recess 1001, and kelly 1002 joint is in the inside of card hole 9, spring 1003 fixed connection is in the inside of recess 1001, spring 1003 fixed connection is in the one end of kelly 1002, guide way 13 has been seted up to the inside of outlet duct 6, the outside fixedly connected with guide block 14 of filter 8, the inside fixedly connected with magnet 15 of guide way 13.

Through the filter 8, can filter the produced waste gas of electrolysis, when changing filter 8, press the inside of card hole 9 with kelly 1002, at this moment the filter 8 loses the restriction, then with filter 8 from the inside of outlet duct 6 take out can, during the installation, press the inside to recess 1001 with kelly 1002, spring 1003 is compressed simultaneously, then with guide block 14 alignment guide way 13, push into the inside of outlet duct 6 with filter 8 again, when card pole 1002 meets with calorie hole 9, spring 1003 can promote kelly 1002 card and go into the inside of kelly 1002, the installation of filter 8 has just so been accomplished, can adsorb guide block 14 through magnet 15 simultaneously, make the installation more firm like this.

As shown in fig. 4, the inside of the groove 1001 is communicated with a limiting groove 11, a limiting plate 12 is fixedly connected to the outside of the clamping rod 1002, and the clamping rod 1002 is slidably connected with the limiting groove 11 through the limiting plate 12.

Through the limiting plate 12 of sliding connection in inside spacing groove 11, make kelly 1002 unable rotate in the inside of recess 1001 like this, it is more stable when messenger's kelly 1002 removes.

The working principle is as follows: during the use, can add hyaluronic acid and hyaluronidase to the inside of hydrolysis tank 1 through inlet pipe 3, carry out electrolytic reaction, then seal inlet pipe 3, can open discharging pipe 4 through valve 5 and carry out the ejection of compact after the reaction, heating pipe 701 starts during the reaction, heat hydrolysis tank 1, and can monitor hydrolysis tank 1 inside temperature through temperature sensor 702, if the temperature exceeds the settlement temperature, temperature sensor 702 sends the signal of telecommunication this moment and gives external switch, make heating pipe 701 stop heating, filter 8 starts and dispels the heat, reduce hydrolysis tank 1 inside temperature, it closes to get back to the settlement through temperature sensor 702, through filter 8, can filter the waste gas that the electrolysis produced, when changing filter 8, press kelly 1002 out the inside of kelly 9, at this moment filter 8 loses the restriction, then take out filter 8 from the inside of outlet duct 6, during the installation, press kelly 1002 to the inside of recess 1001, the spring is compressed simultaneously, then aim at guide block 14 at guide way 13, push filter 8 into the inside of outlet duct 6 again, when kelly 1002 meets with kelly, the kelly 1003, the kelly passes through the inside magnet that the kelly can be installed like this, filter 14 has just so the installation has been accomplished the installation.

In the description of the present invention, it should be noted that the terms "vertical", "upper", "lower", "horizontal", and the like indicate the directions or positional relationships based on the directions or positional relationships shown in the drawings, which are only for the convenience of describing the present invention and simplifying the description, but do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and thus, should not be construed as limiting the present invention.

In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing embodiments, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The utility model provides a device of separation ultra-low molecular hyaluronic acid tetrasaccharide, hexasaccharide, includes hydrolysis tank (1), its characterized in that, the bottom fixedly connected with of hydrolysis tank (1) is evenly distributed's landing leg (2), the top intercommunication of hydrolysis tank (1) has inlet pipe (3), the bottom intercommunication of hydrolysis tank (1) has discharging pipe (4), be provided with valve (5) on discharging pipe (4), the top intercommunication of hydrolysis tank (1) has outlet duct (6), the inside of hydrolysis tank (1) is provided with accuse temperature subassembly (7).

2. The device for separating the ultra-low molecular weight hyaluronic acid tetrasaccharide and the ultra-low molecular weight hyaluronic acid hexasaccharide according to claim 1, wherein the temperature control component (7) comprises a heating pipe (701), a temperature sensor (702) and a heat dissipation fan (703), the heating pipe (701) is fixedly connected inside the hydrolysis tank (1), the temperature sensor (702) is fixedly connected inside the hydrolysis tank (1), the heat dissipation fan (703) is fixedly connected inside the air outlet pipe (6), and the heat dissipation fan (703) and the heating pipe (701) are both electrically connected with an external switching power supply through the temperature sensor (702).

3. The device for separating the ultra-low molecular weight hyaluronan tetrasaccharide and the ultra-low molecular weight hyaluronan hexasaccharide according to claim 1, wherein a filter plate (8) is arranged inside the air outlet pipe (6), the air outlet pipe (6) is provided with clamping holes (9) which are symmetrically distributed, fixing components (10) which are symmetrically distributed are arranged inside the filter plate (8), and the filter plate (8) is connected with the air outlet pipe (6) through the fixing components (10).

4. The device for separating the ultra-low molecular weight hyaluronan tetrasaccharide and the ultra-low molecular weight hyaluronan hexasaccharide of claim 3, wherein the fixing component (10) comprises a groove (1001), a clamping rod (1002) and a spring (1003), the groove (1001) is arranged outside the filter plate (8), the clamping rod (1002) is movably connected inside the groove (1001), the clamping rod (1002) is clamped inside the clamping hole (9), the spring (1003) is fixedly connected inside the groove (1001), and the spring (1003) is fixedly connected at one end of the clamping rod (1002).

5. The device for separating the ultra-low molecular weight hyaluronic acid tetrasaccharide and the ultra-low molecular weight hyaluronic acid hexasaccharide according to claim 4, wherein the groove (1001) is internally communicated with a limiting groove (11), the outside of the clamping rod (1002) is fixedly connected with a limiting plate (12), and the clamping rod (1002) is slidably connected with the limiting groove (11) through the limiting plate (12).

6. The device for separating the ultra-low molecular weight hyaluronan tetrasaccharide and the ultra-low molecular weight hyaluronan hexasaccharide according to claim 3, wherein the gas outlet pipe (6) is internally provided with a guide groove (13), the outside of the filter plate (8) is fixedly connected with a guide block (14), and the inside of the guide groove (13) is fixedly connected with a magnet (15).