CN217796729U - A equipment for concentrating mesenchymal stem cell exosome - Google Patents
A equipment for concentrating mesenchymal stem cell exosome Download PDFInfo
- Publication number
- CN217796729U CN217796729U CN202221720206.8U CN202221720206U CN217796729U CN 217796729 U CN217796729 U CN 217796729U CN 202221720206 U CN202221720206 U CN 202221720206U CN 217796729 U CN217796729 U CN 217796729U
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- CN
- China
- Prior art keywords
- cover
- centrifuge body
- headstock
- mesenchymal stem
- stem cell
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- Expired - Fee Related
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- 210000002901 mesenchymal stem cell Anatomy 0.000 title claims abstract description 16
- 210000001808 exosome Anatomy 0.000 title claims abstract description 14
- 230000000087 stabilizing effect Effects 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 4
- 230000003139 buffering effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 238000000464 low-speed centrifugation Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
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Abstract
The utility model discloses an equipment for concentrating mesenchymal stem cell exosome, including centrifuge body, cover, rotor head seat and rotor head lid, the avris of cover and centrifuge body is connected, the rotor head seat is installed inside centrifuge body, the rotor head lid is connected with the rotor head seat, the sleeve pipe has been placed on the rotor head seat, be provided with the spacing ring on the rotor head seat, the outside of spacing ring is provided with eight connecting plates, the other end of connecting plate is provided with the connection round pad, four the surface of connecting plate is provided with the bracing piece, the surface of centrifuge body is provided with buffer gear, buffer gear includes connecting block, blotter and rotary mechanism; the bracing piece is supported by the cover of turning round, makes connecting plate, connection circular gasket pushed down, connects the circular gasket and plays spacing sheathed tube effect, and the cover lid is fashionable, and the avris of cover pushes down the blotter, and the blotter moves down, and the cover obtains the buffering to the effort of blotter, avoids centrifuge body, cover to receive the damage.
Description
Technical Field
The utility model belongs to the technical field of centrifugal equipment, concretely relates to an equipment that is used for concentrated mesenchymal stem cell exosome.
Background
The laboratory centrifuge plays a role in separating substances with different densities and different particle sizes in suspension or emulsion, can eliminate cell debris, microbubbles or apoptosis problems through low-speed centrifugation, is suitable for the preparation of the mesenchymal stem cell exosomes, and can be widely applied to the fields of chemical industry, pharmacy and the like.
When an existing low-speed laboratory centrifuge carries out centrifugal treatment on mesenchymal stem cells, a cover and a core cover are closed to generate acting force, and the stability of a sleeve on a rotating head seat is affected.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an equipment for concentrating mesenchymal stem cell exosome to the cover that provides in solving above-mentioned background art closes with heart machine lid and produces the effort, and the sleeve pipe stability on the headstock receives the problem of influence.
In order to achieve the above purpose, the utility model provides a following technical scheme: the utility model provides an equipment for concentrating mesenchymal stem cell exosome, includes centrifuge body, cover, headstock and headstock lid, and the cover rotates with centrifuge body to be connected, the cover that can open and shut, is convenient for get and puts the headstock, and the headstock lid closes through the screw thread soon with the headstock and is connected, the dismouting headstock of being convenient for, the avris of cover and centrifuge body is connected, the headstock is installed inside centrifuge body, the headstock lid is connected with the headstock, the sleeve pipe has been placed on the headstock, be provided with the spacing ring on the headstock, the outside of spacing ring is provided with eight connecting plates, and connecting plate and spacing ring structure as an organic whole, the other end of connecting plate is provided with the connection gasket, connects the gasket and passes through glue bonding connection, four with the connecting plate the surface of connecting plate is provided with the bracing piece, closes through the screw thread soon between bracing piece and the connecting plate and is connected, centrifuge body's surface is provided with buffer gear, buffer gear includes connecting block, blotter and rotary mechanism, and the connecting block is installed on centrifuge body through the screw, the torsional spring includes connecting rod, reference column, firm torsional spring piece and torsional spring piece, the reference column is installed at the connecting block internal surface, the torsional spring piece outside, the torsional spring piece is installed in the blotter bottom, the connecting rod, the firm reference column, piece between connecting rod, the connecting rod, torsional spring piece is installed.
Preferably, the surface of the rotating head seat close to the circle center is symmetrically provided with round holes, the limiting ring is provided with two convex columns, the convex columns are matched with the round holes, the convex columns are embedded into the round holes, and the limiting ring is positioned and convenient to place.
Preferably, the centre of a circle of connecting the cushion is provided with circular shape arch, eight connecting plate, connection cushion evenly distributed, it corresponds with the sleeve pipe to connect the cushion, it is coaxial with the sleeve pipe to connect the cushion, makes and connects cushion and sleeve pipe one-to-one, makes the sleeve pipe spacing by connecting the cushion.
Preferably, the bracing piece bottom is connected with the connecting plate, the top of bracing piece is the ball shape, when the swivel lid was closed with the swivel base through the screw soon and is connected, the internal surface of swivel lid was tangent with the ball top of bracing piece, and the bracing piece was withheld to the swivel lid, made the connecting plate compressed tightly, avoided the sleeve pipe to rock at rotatory in-process.
Preferably, a movable cavity is formed in the connecting block, one end of the torsion spring is rotatably connected with the stabilizing block, and the cushion pad is slidably connected with the connecting block.
Preferably, the sleeve comprises a tube body and a tube cover, and a ring gasket is arranged on the outer side, close to the tube cover, of the tube body of the centrifuge body.
Compared with the prior art, the beneficial effects of the utility model are that:
1. through spacing ring, connecting plate, the connection pad and the bracing piece that set up, the bracing piece is supported by the rotor lid, makes connecting plate, connection pad pushed down, connects the pad and plays spacing sheathed tube effect, avoids when rotor seat is rotatory, and sleeve pipe self is unstable, influences centrifugal effect.
2. Through connecting block, connecting rod, blotter and the torsional spring that sets up, the cover lid is fashionable, and the avris of cover pushes down the blotter, and the blotter moves down, and the cover becomes the elastic force of torsional spring to the effort of blotter, and the effort that the cover lid closed obtains the conversion, avoids the effort damage centrifuge body, the cover that cover and centrifuge body collision produced.
Drawings
Fig. 1 is a schematic structural view of the present invention;
fig. 2 is a schematic top view of the turret base of the present invention;
FIG. 3 is a schematic cross-sectional view of the stop collar of the present invention;
fig. 4 is a front view structural diagram of the casing of the present invention;
FIG. 5 is a schematic cross-sectional view of the connecting block of the present invention;
in the figure: 1. a centrifuge body; 2. a machine cover; 3. a turret base; 4. a rotating head cover; 5. connecting blocks; 6. a connecting rod; 7. a cushion pad; 8. a limiting ring; 9. a connecting plate; 10. connecting the round cushion; 11. a sleeve; 12. a support bar; 13. a ring pad; 14. a positioning column; 15. a torsion spring; 16. and (7) stabilizing the block.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Examples
Referring to fig. 1 to 5, the present invention provides a technical solution: an apparatus for concentrating mesenchymal stem cell exosome comprises a centrifuge body 1, a cover 2, a rotary head seat 3 and a rotary head cover 4, wherein the cover 2 is connected with the side of the centrifuge body 1, the rotary head seat 3 is installed in the centrifuge body 1, the rotary head cover 4 is connected with the rotary head seat 3, a sleeve 11 is placed on the rotary head seat 3, the sleeve 11 can be taken and placed, a limiting ring 8 is arranged on the rotary head seat 3, the limiting ring 8 can be taken and placed, eight connecting plates 9 are arranged on the outer side of the limiting ring 8, a connecting round pad 10 is arranged at the other end of each connecting plate 9, the connecting round pad 10 corresponds to the sleeve 11, the connecting round pad 10 plays a role of limiting the sleeve 11, supporting rods 12 are arranged on the surfaces of the four connecting plates 9, when the rotary head cover 4 is connected with the rotary head seat 3 through threaded screwing, the inner surface of the rotary head cover 4 is tangent to the top end of a round ball of the supporting rod 12, the supporting rods 12 are propped against the rotary head cover 4, so that the connecting plates 9 and the connecting round pads 10 keep stable state, the surface of centrifuge body 1 is provided with buffer gear, buffer gear includes connecting block 5, blotter 7 and rotary mechanism, rotary mechanism includes connecting rod 6, reference column 14, torsional spring 15 and firm piece 16, reference column 14 is installed at 5 internal surfaces in the connecting block, 15 covers of torsional spring are established in the reference column 14 outside, firm piece 16 is installed in blotter 7 bottom, connecting rod 6 is installed at torsional spring 15, between firm piece 16, connecting rod 6 is in the tilt state, when cover 2 is closed, the avris of cover 2 pushes down blotter 7, blotter 7 moves down, torsional spring 15 can shrink in the vertical direction, connecting rod 6 is rotatory, torsional spring 15 is in the shrink state, the effort of cover 2 to blotter 7 becomes the elastic force of torsional spring 15, the effort that cover 2 closed obtains the conversion, avoid cover 2 and centrifuge body 1 collision effort that produces to damage centrifuge body 1, A cover 2.
In this embodiment, circular holes are symmetrically disposed on the surface of the turret base 3 close to the center of the circle, two protruding columns are disposed on the limiting ring 8, the protruding columns are matched with the circular holes, the limiting ring 8 can be accurately placed on the turret base 3, and the limiting ring 8 is positioned.
In this embodiment, the circle center of the connection round pad 10 is provided with a circular protrusion, the eight connection plates 9 and the connection round pad 10 are uniformly distributed, the connection round pad 10 corresponds to the sleeve 11, the connection round pad 10 is coaxial with the sleeve 11, the sleeve 11 is placed on the rotary head base 3, the connection round pad 10 is made of a sponge material, and the connection round pad 10 plays a role of limiting the sleeve 11, so that the sleeve 11 is kept in a stable state.
In this embodiment, the bottom end of the support rod 12 is connected to the connecting plate 9, the top end of the support rod 12 is in a spherical shape, when the swivel cover 4 is screwed to the swivel base 3 through the screw threads, the inner surface of the swivel cover 4 is tangent to the spherical top end of the support rod 12, and the support rod 12 is abutted by the swivel cover 4, so that the connecting plate 9 and the connecting pad 10 are kept in a stable state.
In this embodiment, the movable chamber has been seted up in connecting block 5, the one end of torsional spring 15 rotates with firm piece 16 to be connected, blotter 7 and 5 sliding connection of connecting block, torsional spring 15 is fixed a position by reference column 14, connecting rod 6 is in the tilt state, the cover 2 is fashionable, the avris of cover 2 pushes down blotter 7, blotter 7 moves down, torsional spring 15 can shrink in vertical direction, connecting rod 6 is rotatory, torsional spring 15 is in the shrink state, cover 2 becomes the elastic force of torsional spring 15 to the effort of blotter 7, the effort that the cover 2 lid closed obtains the conversion, avoid cover 2 and centrifuge body 1 collision effort damage centrifuge body 1 that produces, cover 2.
In this embodiment, sleeve pipe 11 includes pipe shaft and tube cap, and the outside that centrifuge body 1 pipe shaft is close to the tube cap is provided with ring pad 13, and ring pad 13 is made by sponge material, and ring pad 13 and the laminating of headstock 3, ring pad 13 play the stabilizing effect, and the effort of avoiding cover 2 and centrifuge body 1 collision to produce causes the influence to sleeve pipe 11.
The utility model discloses a theory of operation and use flow:
when the low-speed centrifuge is used for processing mesenchymal stem cells, the sleeve 11 is placed on the rotating head base 3, the annular pad 13 is attached to the rotating head base 3, the annular pad 13 plays a stabilizing role, and the sleeve 11 is prevented from being influenced by acting force generated by collision of the cover 2 and the centrifuge body 1;
the limiting ring 8 is accurately placed on the rotary head seat 3, when the rotary head cover 4 is connected with the rotary head seat 3 in a threaded screwing mode, the inner surface of the rotary head cover 4 is tangent to the top end of a ball of the supporting rod 12, the supporting rod 12 is abutted by the rotary head cover 4, the connecting plate 9 and the connecting round pad 10 are kept in a stable state, the connecting round pad 10 plays a role of limiting the sleeve 11, the sleeve 11 is kept in a stable state, and the phenomenon that the sleeve 11 is unstable and influences the centrifugal effect when the rotary head seat 3 rotates is avoided;
connecting rod 6 is in the tilt state, and cover 2 is covered fashionably, and cover 2's avris pushes down blotter 7, and blotter 7 moves down, and torsional spring 15 can shrink in vertical direction, and connecting rod 6 is rotatory, and torsional spring 15 is in the contraction state, and cover 2 becomes torsional spring 15's elastic force to blotter 7's effort, and the effort that cover 2 lid closed obtains the conversion, avoids cover 2 and 1 collision of centrifuge body to produce effort damage centrifuge body 1, cover 2.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. The utility model provides an equipment for concentrating mesenchymal stem cell exosome, includes centrifuge body (1), cover (2), headstock (3) and headstock lid (4), the avris of cover (2) and centrifuge body (1) is connected, install inside centrifuge body (1) in headstock (3), headstock lid (4) is connected with headstock (3), sleeve pipe (11), its characterized in that have been placed on headstock (3): be provided with spacing ring (8) on headstock (3), the outside of spacing ring (8) is provided with eight connecting plates (9), the other end of connecting plate (9) is provided with connects round pad (10), four the surface of connecting plate (9) is provided with bracing piece (12), the surface of centrifuge body (1) is provided with buffer gear, buffer gear includes connecting block (5), blotter (7) and rotary mechanism, rotary mechanism includes connecting rod (6), reference column (14), torsional spring (15) and firm piece (16), install at connecting block (5) internal surface reference column (14), torsional spring (15) cover is established in reference column (14) outside, install in blotter (7) bottom firm piece (16), connecting rod (6) are installed between torsional spring (15), firm piece (16).
2. An apparatus for concentrating mesenchymal stem cell exosomes according to claim 1, characterised in that: round holes are symmetrically formed in the surface, close to the circle center, of the rotary head seat (3), two convex columns are arranged on the limiting ring (8), and the convex columns are matched with the round holes.
3. An apparatus for concentrating mesenchymal stem cell exosomes according to claim 1, characterised in that: the circle center of connecting circular pad (10) is provided with circular shape arch, eight connecting plate (9), connection circular pad (10) evenly distributed, it corresponds with sleeve pipe (11) to connect circular pad (10), it is coaxial with sleeve pipe (11) to connect circular pad (10).
4. An apparatus for concentrating mesenchymal stem cell exosomes according to claim 1, characterised in that: the utility model discloses a rotary table, including bracing piece (12), top for ball shape, when swivel lid (4) and swivel base (3) are connected through the screw thread soon, the ball top of swivel lid (4) internal surface and bracing piece (12) is tangent.
5. An apparatus for concentrating mesenchymal stem cell exosomes according to claim 1, characterised in that: a movable cavity is formed in the connecting block (5), one end of the torsion spring (15) is rotatably connected with the stabilizing block (16), and the buffer pad (7) is slidably connected with the connecting block (5).
6. An apparatus for concentrating mesenchymal stem cell exosomes according to claim 1, characterised in that: the sleeve (11) comprises a tube body and a tube cover, and a ring pad (13) is arranged on the outer side, close to the tube cover, of the tube body of the centrifuge body (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221720206.8U CN217796729U (en) | 2022-07-05 | 2022-07-05 | A equipment for concentrating mesenchymal stem cell exosome |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221720206.8U CN217796729U (en) | 2022-07-05 | 2022-07-05 | A equipment for concentrating mesenchymal stem cell exosome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN217796729U true CN217796729U (en) | 2022-11-15 |
Family
ID=83962268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221720206.8U Expired - Fee Related CN217796729U (en) | 2022-07-05 | 2022-07-05 | A equipment for concentrating mesenchymal stem cell exosome |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN217796729U (en) |
-
2022
- 2022-07-05 CN CN202221720206.8U patent/CN217796729U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20221115 |