CN217707137U

CN217707137U - Reagent storage device

Info

Publication number: CN217707137U
Application number: CN202221630736.3U
Authority: CN
Inventors: 蒋传有; 汤绍周; 张焕贵; 刘宾
Original assignee: Guangzhou Wondfo Biotech Co Ltd
Current assignee: Guangzhou Wondfo Biotech Co Ltd
Priority date: 2022-06-28
Filing date: 2022-06-28
Publication date: 2022-11-01
Anticipated expiration: 2032-06-28

Abstract

The utility model relates to a reagent storage device, reagent storage device include storing container and gasbag. When the reagent sucking device is used, in the process of sucking out a reagent through the pipette, the air pressure in the first chamber is reduced, and the air in the air bag can correspondingly enter the first chamber to balance the air pressure in the first chamber; when the reagent is spit out into the first chamber through the pipette, the internal air pressure of the first chamber is increased along with the reagent, so that the air in the first chamber correspondingly enters the air bag, and the air pressure of the first chamber can be balanced. Therefore, on one hand, the air pressure in the first chamber is balanced by the air bag, namely, no gas in the external environment enters or exits the first chamber, so that the reagent and the external environment can be isolated as far as possible; on the other hand, the storage container does not need to expand or contract, and more materials which do not influence the performance of the reagent are selected, so that the storage container can be well compatible with the reagent; in addition, the reagent can be ensured to be normally sucked and spit.

Description

Reagent storage device

Technical Field

The utility model relates to an external diagnostic reagent stores technical field, especially relates to a reagent storage device.

Background

In the field of in vitro diagnostic techniques, the prevention, diagnosis, treatment monitoring, prognosis observation, health status evaluation, and prediction of genetic diseases, in general, in vitro diagnostic reagents are required, which can be used alone or in combination with instruments, devices, apparatuses, or systems. The in-vitro diagnostic reagent comprises a reagent, a kit, a calibrator, a quality control product and the like for in-vitro detection. There are many problems associated with storing and using reagents in an instrument, such as: 1. the complex environment can cause the instability and the failure of the reagent and influence the test result; 2. the material which is compatible with the reagent chemistry is very little, and most of the material can pollute the reagent and even lose efficacy; 3. when the reagent is used, the reagent needs to be sucked and spit, so that the reagent bottle cannot be completely sealed. In particular, some substrate reagents that involve luminescence are particularly sensitive to environmental contamination and require special attention when storing the reagents. For example, many chemiluminescent substrate reagents can greatly affect the test results upon contact with the environment.

In order to solve the application problem of the reagent, the existing schemes mainly comprise the following three types:

1. the check valve is added on the reagent bottle to allow outside air to enter the reagent bottle, and the air in the reagent bottle cannot flow out, namely the scheme can only reduce the back-and-forth flow of the air between the reagent bottle and the outside to a certain extent, but cannot isolate the outside air from entering the reagent bottle to contact with the reagent;

2. the reagent bottle is additionally provided with a first filter for filtering and purifying air entering the reagent bottle, but the scheme is limited by filtering precision, can only filter external air to a certain degree, and cannot isolate the external air from entering the reagent bottle to contact with the reagent;

3. by using the bagged reagent, the scheme can well separate the outside air from the reagent, but the bagged reagent is difficult to find the material which is good in chemical compatibility with the reagent and can be bagged.

Disclosure of Invention

Based on this, there is a need to overcome the drawbacks of the prior art and to provide a reagent storage device that can isolate the reagent from the external environment as much as possible; the device itself does not affect the performance of the reagent, i.e. is well compatible with the reagent; ensure the normal sucking and spitting of the reagent.

The technical scheme is as follows: a reagent storage device, the reagent storage device comprising:

the reagent storage device comprises a storage container and a control device, wherein the storage container is provided with a first chamber for containing a reagent and a pipette communicated with the first chamber, and the pipette penetrates through the storage container and extends out of the storage container; and

the air bag is communicated with the first chamber and is used for balancing the air pressure of the first chamber during the process of sucking and spitting the reagent by the pipette.

In one embodiment, the airbag is located outside the storage container, and the gas inlet and outlet portion of the airbag is communicated with the top portion of the storage container.

In one embodiment, the reagent storage device further comprises a first filter; the bladder is in communication with the first chamber through the first filter.

In one embodiment, the storage container is provided with a second chamber separated from the first chamber, and the airbag is arranged in the second chamber.

In one embodiment, a partition for separating the first chamber from the second chamber is connected to the inner wall of the storage container; the first chamber is positioned above the second chamber; an opening penetrating along the thickness direction of the partition is formed in the partition, a gas inlet and outlet portion of the airbag extends into the first cavity through the opening, and the gas inlet and outlet portion of the airbag is in sealing contact with the opening; a first breathable waterproof membrane is arranged on the gas inlet and outlet part of the air bag.

In one embodiment, a partition member for partitioning the first chamber and the second chamber is connected to the inner wall of the storage container, the first chamber is located below the second chamber, an opening penetrating the partition member along the thickness direction of the partition member is formed in the partition member, a gas inlet and outlet portion of the airbag is arranged in the opening, and the gas inlet and outlet portion of the airbag is in sealing contact with the opening;

or the inner wall of the storage container is connected with a partition for separating the first chamber from the second chamber, the first chamber and the second chamber are sequentially and adjacently arranged along the horizontal direction, an opening penetrating along the thickness direction of the partition is formed in the top part of the partition, a gas inlet and outlet part of the airbag is arranged in the opening, and the gas inlet and outlet part of the airbag is in sealed butt joint with the opening.

In one embodiment, a second breathable waterproof membrane is arranged on the gas inlet and outlet part of the air bag.

In one embodiment, the reagent storage device further comprises a second filter; the bladder is in communication with the first chamber through the second filter.

In one embodiment, the number of the air bags is at least two; one of the air bags is positioned outside the storage container; the storage container is provided with a second cavity separated from the first cavity, and the other air bag is positioned in the second cavity.

In one embodiment, the reagent is a substrate solution reagent.

In one embodiment, the gas inside the airbag is purified gas; and/or a mouth part is arranged at the top of the storage container, a cover body covers the mouth part, and the pipette penetrates through the cover body and extends into the first cavity.

In the reagent storage device, in the using process, the reagent is placed in the first chamber, and when the reagent is sucked out through the pipette, the air pressure in the first chamber is reduced, and the air in the air bag can correspondingly enter the first chamber to balance the air pressure in the first chamber; when the reagent is spit out into the first chamber through the pipette, the internal air pressure of the first chamber is increased along with the reagent, so that the air in the first chamber correspondingly enters the air bag, and the air pressure of the first chamber can be balanced. Therefore, on one hand, the air pressure in the first chamber is balanced through the air bag, namely, no air in the external environment enters and exits the first chamber, so that the reagent and the external environment can be isolated as far as possible; on the other hand, the storage container does not need to expand or contract, and more materials which do not influence the performance of the reagent are selected, so that the storage container can be well compatible with the reagent; in addition, the reagent can be ensured to be normally sucked and spit.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this application, are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification.

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly described below, and it is obvious that the drawings in the description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained without creative efforts.

Fig. 1 is a schematic structural diagram of a reagent storage device according to an embodiment of the present invention;

FIG. 2 is a schematic structural diagram of a reagent storage device according to another embodiment of the present invention;

fig. 3 is a schematic cross-sectional structure view of the reagent storage apparatus shown in fig. 2.

10. A storage container; 11. a first chamber; 12. a pipette; 13. a mouth; 14. a cover body; 15. a second chamber; 16. a spacer; 161. an opening; 20. an air bag; 21. a gas inlet and outlet part; 22. a first breathable waterproof membrane; 30. a first filter.

Detailed Description

In order to make the above objects, features and advantages of the present invention more comprehensible, embodiments of the present invention are described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. The present invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein, as those skilled in the art will be able to make similar modifications without departing from the spirit and scope of the present invention.

Referring to fig. 1 to 3, fig. 1 shows a schematic structural diagram of a reagent storage device according to an embodiment of the present invention, fig. 2 shows a schematic structural diagram of a reagent storage device according to another embodiment of the present invention, and fig. 3 shows a schematic sectional structural diagram of the reagent storage device shown in fig. 2. An embodiment of the utility model provides a pair of reagent storage device, reagent storage device includes: a storage container 10 and an airbag 20. The storage container 10 is provided with a first chamber 11 for housing a reagent, and a pipette 12 communicating with the first chamber 11, the pipette 12 protruding through the storage container 10 to the outside of the storage container 10. The air bag 20 is communicated with the first chamber 11, and the air bag 20 is used for balancing the air pressure of the first chamber 11 during the process of sucking and spitting the reagent by the pipette 12.

In the reagent storage device, during use, the reagent is placed in the first chamber 11, and when the reagent is sucked out through the pipette 12, the air pressure in the first chamber 11 is reduced, and accordingly, the air in the air bag 20 can enter the first chamber 11 to balance the air pressure in the first chamber 11; during the process of discharging the reagent into the first chamber 11 through the pipette 12, the internal pressure of the first chamber 11 increases, so that the gas in the first chamber 11 enters the air bag 20 correspondingly, and the air pressure of the first chamber 11 can be balanced. Thus, on the one hand, since the equalization of the gas pressure in the first chamber 11 is performed by the gas bag 20, i.e. no gas from the external environment enters or exits the first chamber 11, the reagent can be isolated from the external environment as much as possible; on the other hand, the storage container 10 does not need to expand or contract, and more materials which do not influence the performance of the reagent are selected, so that the storage container can be well compatible with the reagent; in addition, the reagent can be ensured to be normally sucked and spit.

In one embodiment, the storage container 10 includes, but is not limited to, a storage bottle, a storage canister, and a storage box.

In one embodiment, the balloon 20 includes, but is not limited to, a soft balloon, an elastic balloon, and the like that can be inflated and deflated.

In one embodiment, the reagent includes, but is not limited to, a substrate solution reagent.

In one embodiment, the container 10 is made of a hard material, so that the container 10 is not deformed during the sucking and spitting processes. Specifically, the material of the storage container 10 includes, but is not limited to, plastic, metal parts such as iron, copper, aluminum, etc., wood parts, rubber, etc., and how to select the material can be flexibly adjusted and set according to actual requirements is not limited herein.

Referring to fig. 1, in one embodiment, an airbag 20 is located outside a storage container 10, and a gas inlet and outlet portion 21 of the airbag 20 communicates with a top portion of a first chamber 11. Therefore, in the process of spitting and sucking the reagent, the gas at the top position in the first chamber 11 correspondingly enters and exits the air bag 20, so that the liquid in the first chamber 11 can be prevented from entering the air bag 20, and the reagent can be guaranteed to be normally spitted and sucked.

The top portion of the first chamber 11 refers to a region above the reagent level in the first chamber 11. The area above the liquid level of the reagent is gas, and in the process of spitting and sucking the reagent, the gas in the first chamber 11 correspondingly enters and exits the air bag 20, so that the liquid in the first chamber 11 can be prevented from entering the air bag 20, and the reagent can be guaranteed to be normally spitted.

Referring to FIG. 1, in one embodiment, the reagent storage device further comprises a first filter 30. The air bag 20 communicates with the first chamber 11 through the first filter 30. Therefore, the gas can be filtered by the first filter 30 in the process of flowing through the first filter 30, and the stability of the reagent can be ensured to the maximum extent.

Specifically, the first filter 30 is disposed on the gas inlet/outlet portion 21 of the airbag 20, or the first filter 30 is disposed between the gas inlet/outlet portion 21 of the airbag 20 and the storage container 10, or the first filter 30 is disposed on the top of the storage container 10 and connected to the gas inlet/outlet portion 21 of the airbag 20.

Referring to fig. 1 to 3, in one embodiment, a mouth 13 is formed at the top of the storage container 10, and a cover 14 covers the mouth 13. The first filter 30 is specifically disposed on the cover 14 and communicates with the first chamber 11 and the airbag 20, respectively.

Referring to fig. 2 and 3, in one embodiment, the storage container 10 has a second chamber 15 separated from the first chamber 11, and the airbag 20 is disposed in the second chamber 15. In this way, the air bag 20 is not limited to be disposed outside the storage container 10, and the air bag 20 may be disposed inside the storage container 10, so that the reagent can be normally sucked and discharged. In addition, since the airbag 20 is located inside the storage container 10, the airbag 20 can be protected.

Referring to fig. 2 and 3, in one embodiment, a partition 16 is connected to an inner wall of the storage container 10 to separate the first chamber 11 from the second chamber 15. The first chamber 11 is located above the second chamber 15. The separator 16 has an opening 161 formed therethrough in the thickness direction thereof, the gas inlet/outlet portion 21 of the airbag 20 extends into the first chamber 11 through the opening 161, and the gas inlet/outlet portion 21 of the airbag 20 is in sealing contact with the opening wall of the opening 161. The gas inlet/outlet portion 21 of the airbag 20 is provided with a first air-permeable waterproof film 22. Thus, in the reagent sucking and spitting process, the gas in the air bag 20 can enter and exit the first chamber 11, so that the air pressure of the first chamber 11 is balanced, and the normal sucking and spitting of the reagent is ensured. In addition, under the action of the first waterproof and breathable film, the liquid in the first chamber 11 is prevented from entering the air bag 20 not only in the reagent sucking and spitting process, but also in the transportation state, the liquid in the first chamber 11 is prevented from entering the air bag 20.

It should be noted that the breathable waterproof membrane functions to allow gas to pass through while preventing liquid from flowing through.

It should be noted that the partition 16 includes, but is not limited to, partition structures with various shapes and structures such as a partition board, a partition block, a partition sheet, etc., as long as the cavity of the storage container 10 can be partitioned into the first cavity 11 and the second cavity 12, and the specific structural form is not limited herein, and can be flexibly adjusted and configured according to actual requirements.

In another embodiment, a partition 16 is connected to an inner wall of the storage container 10 to separate the first chamber 11 and the second chamber 15, the first chamber 11 is located below the second chamber 15, an opening 161 is formed in the partition 16 and penetrates through the partition along a thickness direction of the partition, the gas inlet/outlet portion 21 of the airbag 20 is disposed in the opening 161, and the gas inlet/outlet portion 21 of the airbag 20 is in sealing contact with the opening 161. Thus, in the reagent sucking and spitting process, the gas in the air bag 20 can enter and exit the first chamber 11, so that the air pressure of the first chamber 11 is balanced, and the normal sucking and spitting of the reagent is ensured.

In still another embodiment, a partition 16 for partitioning the first chamber 11 and the second chamber 15 is connected to an inner wall of the storage container 10, the first chamber 11 and the second chamber 15 are sequentially arranged adjacent to each other along a horizontal direction, an opening 161 penetrating along a thickness direction of the partition 16 is formed on a top portion of the partition, the gas inlet/outlet portion 21 of the airbag 20 is disposed at the opening 161, and the gas inlet/outlet portion 21 of the airbag 20 is in sealing abutment with the opening 161. Thus, in the reagent sucking and spitting process, the gas in the air bag 20 can enter and exit the first chamber 11, so that the air pressure of the first chamber 11 is balanced, and the normal sucking and spitting of the reagent is ensured.

In one embodiment, the gas inlet and outlet portion 21 of the airbag 20 is provided with a second air-permeable waterproof film (not shown). Thus, under the action of the second waterproof and breathable film, the liquid in the first chamber 11 is prevented from entering the air bag 20 not only in the reagent sucking and spitting process, but also in the transportation state, the liquid in the first chamber 11 is prevented from entering the air bag 20.

In one embodiment, the reagent storage device further comprises a second filter (not shown). The air bag 20 communicates with the first chamber 11 through a second filter. Therefore, the gas can be filtered by the second filter in the process of flowing through the second filter, and the stability of the reagent can be ensured to the maximum extent.

The arrangement of the airbag 20 in the storage container 10 is not limited to the bottom, the side, and the top of the first chamber 11 in the above embodiments, and may be flexibly adjusted and arranged according to actual needs, and is not limited herein.

In another embodiment, there are at least two bladders 20. One of the air bags 20 is located outside the storage container 10. The storage container 10 is provided with a second chamber 15 separated from the first chamber 11, and another air bag 20 is located in the second chamber 15.

In one embodiment, the gas inside the airbag 20 is a purified gas.

In one embodiment, the top of the storage container 10 is provided with a mouth 13 and a cover 14 covering the mouth 13, and the pipette 12 extends through the cover 14 into the first chamber 11.

The purified gas refers to a gas that does not react with the reagent, that is, does not affect the stability of the reagent.

In one embodiment, the cover 14 is provided with a liquid suction hole (not shown), the pipette 12 is inserted into the first chamber 11 through the liquid suction hole, and the pipette 12 is in sealing abutment with the wall of the liquid suction hole, so as to ensure the sealing property and prevent air from the external environment from entering the first chamber 11.

It should be noted that the "cover plate" may be a part of the storage container 10, that is, the "cover plate" and the other parts of the storage container 10 are integrally formed; the "cover plate" may be manufactured separately and then integrated with the "other portion of the storage container 10" as a single body.

Note that the "mouth 13" may be a "part of the container 10", that is, the "mouth 13" may be integrally formed with "the other part of the container 10"; the "mouth 13" may be a separate member that is separable from the "other portion of the storage container 10" and may be formed separately and integrated with the "other portion of the storage container 10".

The technical features of the above embodiments can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the above embodiments are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only represent several embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and for simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or to implicitly indicate the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless explicitly defined otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," and "fixed" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meaning of the above terms in the present invention can be understood according to specific situations by those of ordinary skill in the art.

In the present application, unless expressly stated or limited otherwise, a first feature "on" or "under" a second feature may be directly contacting the second feature or the first and second features may be indirectly contacting the second feature through intervening media. Also, a first feature "on," "above," and "over" a second feature may be directly on or obliquely above the second feature, or simply mean that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. As used herein, the terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like are for purposes of illustration only and do not denote a single embodiment.

Claims

1. A reagent storage device, comprising:

the reagent storage device comprises a storage container and a control device, wherein the storage container is provided with a first chamber for containing a reagent, and a pipette communicated with the first chamber, and the pipette penetrates through the storage container and extends out of the storage container; and

2. The reagent storage device of claim 1 wherein the gas bladder is located outside of the storage container, the gas access portion of the gas bladder being in communication with a top portion of the first chamber.

3. The reagent storage device of claim 2, wherein the storage device further comprises a first filter; the bladder is in communication with the first chamber through the first filter.

4. The reagent storage device of claim 1 wherein the storage container is provided with a second chamber separated from the first chamber, the air bladder being disposed within the second chamber.

5. The reagent storage device of claim 4 wherein a partition is attached to the inner reservoir wall separating the first chamber from the second chamber; the first chamber is positioned above the second chamber; an opening penetrating along the thickness direction of the partition is formed in the partition, a gas inlet and outlet portion of the airbag extends into the first cavity through the opening, and the gas inlet and outlet portion of the airbag is in sealing contact with the opening; a first breathable waterproof membrane is arranged on the gas inlet and outlet part of the air bag.

6. The reagent storage device of claim 4, wherein a partition member is connected to an inner wall of the storage container to partition the first chamber from the second chamber, the first chamber is located below the second chamber, an opening is formed in the partition member and penetrates through the partition member in a thickness direction of the partition member, the gas inlet and outlet portion of the gas bag is disposed in the opening, and the gas inlet and outlet portion of the gas bag is in sealing abutment with the opening;

7. The reagent storage device of claim 6 wherein a second gas-permeable, waterproof membrane is provided over the gas access portion of the bladder.

8. The reagent storage device of claim 7, further comprising a second filter; the bladder is in communication with the first chamber through the second filter.

9. The reagent storage device of claim 1 wherein the air pockets are at least two; one of the air bags is positioned outside the storage container; the storage container is provided with a second cavity separated from the first cavity, and the other air bag is positioned in the second cavity.

10. The reagent storage device of any one of claims 1 to 9 wherein the reagent is a substrate solution reagent.

11. The reagent storage device of any one of claims 1 to 9 wherein the gas inside the bladder is a purified gas; and/or a mouth part is arranged at the top of the storage container, a cover body covers the mouth part, and the pipette penetrates through the cover body and extends into the first cavity.