CN217569048U

CN217569048U - Single cell suspension grinder

Info

Publication number: CN217569048U
Application number: CN202123298849.6U
Authority: CN
Inventors: 张添一
Original assignee: Shanghai Naoer Biotechnology Co ltd
Current assignee: Shanghai Naoer Biotechnology Co ltd
Priority date: 2021-12-24
Filing date: 2021-12-24
Publication date: 2022-10-14
Anticipated expiration: 2031-12-24

Abstract

The utility model discloses a unicellular suspension grinder, the on-line screen storage device comprises a base, the upper end fixedly connected with stand of base, it is connected with the rotation seat to rotate on the lateral wall of stand, fixedly connected with device board on the lateral wall of rotation seat, it is provided with stop device to run through on the device board, it is provided with the device groove to run through on the device board, fixedly connected with drive arrangement on the lateral wall of device board, the last downside in device groove all runs through and is provided with the notch, the notch department in device groove is provided with grinder, the upper end fixedly connected with standing seat of base, it has set up the standing groove to run through in the standing seat, place the holding pipe in the standing groove. The utility model has the advantages of reasonable design, have convenient grinding operation, device simple structure easily operates, conveniently changes the benefit of grinding rod.

Description

Single cell suspension grinder

Technical Field

The utility model relates to a unicellular suspension technical field especially relates to a unicellular suspension grinder.

Background

The single cell suspension generally refers to a biological sample liquid which is obtained by processing minced animal tissues or organs with trypsin, is generally used for single cell sequencing engineering tests, and the traditional tissue processing method comprises a mechanical method, including a net rubbing method and a grinding method, and is generally suitable for sample types such as spleen, lymph node and thymus; in addition, there is a milder enzymatic process: trypsin, collagenase, lysozyme, elastase and some commercially packaged combination enzymes, and the types of suitable samples are liver, kidney, heart, lung, spinal cord, brain, intestinal tract, skin, tumor, etc.

In the prior art, the grinding method adopted in the tissue treatment process generally adopts an experimenter to grind tissues by using a grinding rod, the grinding time is long, and physical contact is easy to generate, so that a sample is deteriorated, and therefore, a single cell suspension grinding device is provided.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving the defects existing in the prior art and providing a single cell suspension grinding device.

In order to realize the purpose, the utility model adopts the following technical scheme:

the utility model provides a unicellular suspension grinder, includes the base, the upper end fixedly connected with stand of base, it rotates to be connected with on the lateral wall of stand and rotates the seat, fixedly connected with device board on rotating the lateral wall of seat, it is provided with stop device to run through on the device board, it is provided with the device groove to run through on the device board, fixedly connected with drive arrangement on the lateral wall of device board, the last downside in device groove all runs through and is provided with the notch, the notch department in device groove is provided with grinder, the upper end fixedly connected with of base places the seat, it is provided with the standing groove to run through in the seat to place, place the holding pipe in the standing groove.

Preferably, the limiting device comprises a limiting hole penetrating through the device plate, the upper end of the base is provided with a limiting groove which is in vertical apposition with the limiting hole in a penetrating manner, a limiting inserted rod penetrates through the limiting hole, the lower end of the limiting inserted rod is located in the limiting groove, and the upper end of the limiting inserted rod is fixedly connected with a limiting block.

Preferably, the driving device comprises a fixing frame fixedly connected to the upper end of the device plate, a small motor is fixedly connected to the fixing frame, the tail end of an output shaft of the small motor penetrates through the side wall of the device plate and extends into the device groove to be rotatably connected with the inner wall of the device groove, and a second gear is fixedly connected to the output shaft of the small motor on the side wall of the device groove.

Preferably, the grinding device comprises a square rod arranged at the groove opening of the device, the square rod is located on the side wall of the device groove and fixedly connected with a first gear, the first gear is meshed with a second gear, the lower end of the square rod is provided with a grinding rod, the upper end of the grinding rod is provided with a square groove in a penetrating mode, the lower end of the square rod is located in the square groove, the lower end of the square rod and the inner bottom of the square groove are fixedly connected with magnetic blocks, and the magnetic blocks are magnetically attracted with each other.

Preferably, the inner wall of the placing groove is provided with buffering cotton.

Preferably, the notches on the upper side and the lower side in the groove of the device can be freely moved by the first gear.

The utility model has the following beneficial effects;

the utility model discloses in, through setting up stop device, grinder mutually supports with drive arrangement, set up the grinding operation that this device is used for the unicellular suspension, the grinding rod that utilizes removable formula comes to grind the tissue sample that holds in the pipe 7, the drive power that utilizes the motor replaces manual grinding, time saving and labor saving, grinding rod and square pole in this device are easily dismantled moreover, convenient change and installation, the device board can be free rotate on the stand, conveniently put and hold the pipe, the steadiness of device has also been guaranteed through stop device simultaneously.

Drawings

FIG. 1 is a schematic structural view of a single cell suspension grinding device according to the present invention;

FIG. 2 is a cross-sectional view of the device plate of the single cell suspension grinding device provided by the present invention;

fig. 3 is a schematic diagram of the square rod and its related parts of the single cell suspension grinding device of the present invention.

In the figure: the grinding device comprises a base 1, a limiting inserted rod 2, a limiting block 3, a device plate 4, a square rod 5, a grinding rod 6, a containing pipe 7, a placing seat 8, a small motor 9, a fixing frame 10, a rotating seat 11, a stand column 12, a first gear 13 and a second gear 14.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.

Referring to fig. 1-3, a unicellular suspension grinder, including base 1, the upper end fixedly connected with stand 12 of base 1, it rotates to be connected with on the lateral wall of stand 12 and rotates seat 11, rotate fixedly connected with device board 4 on the lateral wall of seat 11, it is provided with stop device to run through on the device board 4, stop device is including running through the spacing hole that sets up on device board 4, the upper end of base 1 runs through the spacing groove that is provided with spacing hole upper and lower apposition, it is provided with spacing inserted bar 2 to run through in the spacing hole, the lower extreme of spacing inserted bar 2 is located the spacing inslot, the upper end fixedly connected with stopper 3 of spacing inserted bar 2, it is provided with the device groove to run through on the device board 4.

The grinding device comprises a square rod 5 arranged at the position of the groove of the device, the square rod 5 is arranged on the side wall of the groove of the device and is fixedly connected with a first gear 13, the first gear 13 is mutually meshed with a second gear 14, the lower end of the square rod 5 is provided with a grinding rod 6, the upper end of the grinding rod 6 is provided with a square groove, the lower end of the square rod 5 is arranged in the square groove, the lower end of the square rod 5 is fixedly connected with a magnetic block fixedly connected with the inner bottom of the square groove, and the two magnetic blocks are mutually attracted.

Specifically, the upper end fixedly connected with of base 1 places seat 8, it is provided with the standing groove to run through in the seat 8 to place, the inner wall department of standing groove is provided with the buffering cotton, place the holding pipe 7 in the standing groove.

It is worth mentioning, the notch of device inslot upper and lower both sides all can be by first gear 13 free movement, and the experimenter upwards pulls square pole 5 from the upper end, can directly let square pole 5 take first gear 13 and break away from with grinding rod 6, conveniently takes out grinding rod 6.

The utility model discloses in, the experimenter can add the tissue sample that the appropriate amount needs to grind in holding pipe 7, put into the grinding rod 6 that needs to use in holding pipe 7 again, then will hold pipe 7 and put into and place the standing groove on the seat 8 and stabilize, then the experimenter passes through to rotate seat 11 and rotates device board 4, let device board 4 remove and hold pipe 7 directly over, insert spacing inserted bar 2 in spacing downthehole, until letting the lower extreme of spacing inserted bar 2 enter into the spacing inslot, then aim at grinding rod 6 and put into square pole 5 with the notch in device groove, square pole 5's lower extreme can enter into the square inslot of grinding rod 6 upper end and couple together through two magnetic path interconnect, first gear 13 and second gear 14 just in time are located same horizontal position this moment, intermeshing each other, starter start-type small motor 9 through among the prior art can drive square pole 5 and grinding rod 6 synchronous rotation through first gear 13 and second gear 14, can grind the operation to holding the tissue in the pipe 7.

The above, only be the embodiment of the preferred of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, which are designed to be replaced or changed equally, all should be covered within the protection scope of the present invention.

Claims

1. The utility model provides a unicellular suspension grinder, includes base (1), its characterized in that, upper end fixedly connected with stand (12) of base (1), it is connected with rotation seat (11) to rotate on the lateral wall of stand (12), fixedly connected with device board (4) on the lateral wall of rotation seat (11), it is provided with stop device to run through on device board (4), it is provided with the device groove to run through on device board (4), fixedly connected with drive arrangement on the lateral wall of device board (4), the last downside of device groove all runs through and is provided with the notch, the notch department in device groove is provided with grinder, upper end fixedly connected with of base (1) places seat (8), it has set up the standing groove to run through in standing seat (8), place pipe (7) in the standing groove.

2. The single cell suspension grinding device according to claim 1, wherein the limiting device comprises a limiting hole penetrating through the device plate (4), a limiting groove in the same position with the limiting hole is penetrated through the upper end of the base (1), a limiting insertion rod (2) penetrates through the limiting hole, the lower end of the limiting insertion rod (2) is located in the limiting groove, and a limiting block (3) is fixedly connected to the upper end of the limiting insertion rod (2).

3. The single cell suspension grinding device according to claim 1, wherein the driving device comprises a fixing frame (10) fixedly connected to the upper end of the device plate (4), a small motor (9) is fixedly connected to the fixing frame (10), the end of the output shaft of the small motor (9) penetrates through the side wall of the device plate (4) and extends into the device groove to be rotatably connected with the inner wall of the device groove, and a second gear (14) is fixedly connected to the side wall of the output shaft of the small motor (9) in the device groove.

4. The single cell suspension grinding device according to claim 3, wherein the grinding device comprises a square rod (5) arranged at the groove opening of the device, the square rod (5) is fixedly connected with a first gear (13) on the side wall in the device groove, the first gear (13) is meshed with a second gear (14), a grinding rod (6) is arranged at the lower end of the square rod (5), the upper end of the grinding rod (6) is provided with a square groove in a penetrating manner, the lower end of the square rod (5) is arranged in the square groove, magnetic blocks are fixedly connected to the lower end of the square rod (5) and the inner bottom of the square groove, and the two magnetic blocks are magnetically attracted with each other.

5. The single cell suspension grinding device of claim 1, wherein the inner wall of the placement groove is provided with buffering cotton.

6. The single cell suspension grinding device according to claim 4, wherein the notches at the upper and lower sides of the device groove are freely movable by the first gear (13).