CN217548755U - Injection system - Google Patents
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- CN217548755U CN217548755U CN202123442539.7U CN202123442539U CN217548755U CN 217548755 U CN217548755 U CN 217548755U CN 202123442539 U CN202123442539 U CN 202123442539U CN 217548755 U CN217548755 U CN 217548755U
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- 238000002347 injection Methods 0.000 title claims abstract description 172
- 239000007924 injection Substances 0.000 title claims abstract description 172
- 238000003745 diagnosis Methods 0.000 claims abstract description 18
- 238000007789 sealing Methods 0.000 claims abstract description 15
- 239000012530 fluid Substances 0.000 claims description 18
- 239000000463 material Substances 0.000 claims description 16
- 239000000126 substance Substances 0.000 claims description 16
- 238000011065 in-situ storage Methods 0.000 claims description 6
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 3
- 239000002131 composite material Substances 0.000 claims description 3
- 238000001125 extrusion Methods 0.000 claims description 3
- 229960002897 heparin Drugs 0.000 claims description 3
- 229920000669 heparin Polymers 0.000 claims description 3
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 3
- 230000001360 synchronised effect Effects 0.000 abstract description 7
- 230000003068 static effect Effects 0.000 abstract description 2
- 230000002107 myocardial effect Effects 0.000 description 15
- 206010019280 Heart failures Diseases 0.000 description 8
- 238000004891 communication Methods 0.000 description 8
- 238000005452 bending Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 210000002376 aorta thoracic Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 210000005240 left ventricle Anatomy 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 210000004165 myocardium Anatomy 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 210000001765 aortic valve Anatomy 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 230000004064 dysfunction Effects 0.000 description 2
- 210000001105 femoral artery Anatomy 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 230000013011 mating Effects 0.000 description 2
- 238000002054 transplantation Methods 0.000 description 2
- 230000008733 trauma Effects 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 230000003139 buffering effect Effects 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000003205 diastolic effect Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000002324 minimally invasive surgery Methods 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0082—Catheter tip comprising a tool
- A61M25/0084—Catheter tip comprising a tool being one or more injection needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0108—Steering means as part of the catheter or advancing means; Markers for positioning using radio-opaque or ultrasound markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0082—Catheter tip comprising a tool
- A61M25/0084—Catheter tip comprising a tool being one or more injection needles
- A61M2025/0085—Multiple injection needles protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip
- A61M2025/0086—Multiple injection needles protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip the needles having bent tips, i.e. the needle distal tips are angled in relation to the longitudinal axis of the catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M2025/0166—Sensors, electrodes or the like for guiding the catheter to a target zone, e.g. image guided or magnetically guided
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/12—Blood circulatory system
- A61M2210/125—Heart
Abstract
The invention relates to the field of medical instruments, in particular to an injection system, which comprises an injection assembly, wherein the injection assembly comprises one or more injection needles, an injection tube and a diagnosis tube, and a detachable connecting structure is arranged between the injection tube and the diagnosis tube; the injection tube contains the injectate, and the diagnostic tube contains the intervention medium; after the injection tube injects the injectate, part of the injectate is injected into the target tissue, and the rest of the injectate is injected into the target tissue through an intervention medium. The injection tube and the diagnostic tube in the injection system provided by the invention can realize synchronous pushing, synchronous static and synchronous movement, realize sealing and locking reversibility of the injection tube and the diagnostic tube, can be adjusted randomly according to requirements, can realize repeated replacement of the diagnostic tube after other injectables are injected into target tissues by intervention media, ensures that multiple continuous injections of the injectables are realized at the target tissues, and improves the injection efficiency.
Description
The applicant's prior application number 202110791104.9 for 2021 on month 07 and 13, the entire contents of which are hereby incorporated by reference.
Technical Field
The invention belongs to the field of medical instruments, and particularly relates to an injection system.
Background
At present, the morbidity and mortality of heart failure are high, which is a significant cause of death of most patients with cardiovascular diseases, and nearly 2300 million people all over the world suffer from the disease. The heart failure is called heart failure, which means that venous return blood cannot be sufficiently discharged out of the body due to the occurrence of dysfunction of the systolic function or the diastolic function of the heart, so that blood stasis in a venous system and insufficient blood supply in an arterial system are caused, and finally cardiac circulatory system dysfunction is caused. Most of the patients' diseases are caused by the fact that after a plurality of years of daily accumulation, the heart gradually loses the function of pumping blood, all aspects of the functions are gradually weakened, and the heart is enlarged, so that the left ventricle is mainly enlarged, and great negative effects are brought to the life quality and clinical treatment of the patients. The existing treatment schemes include drug therapy, auxiliary equipment and heart transplantation, but different treatment methods face great challenges, for example, the drug therapy generally causes repeated attacks of diseases of many patients, the treatment mode is not suitable for all patients through biventricular pacing, even the physical quality of some patients does not meet the treatment condition, the body has abnormal reactions, and in addition, when the treatment mode is performed through the heart transplantation, the source of heart donors is very limited.
The patent CN113577504a provides a heart failure treatment system, which comprises a control mechanism, a delivery catheter connected with the control mechanism, and an injection module arranged in the delivery catheter; wherein the distal portion of the injection module has a preset configuration; and a guide positioning device disposed at least partially within the delivery catheter; when the distal end of the delivery catheter reaches the target position and the injection module extends from the delivery catheter to the far side gradually, the guiding and positioning device can ensure that the distal end part of the injection module can return to the preset shape according to the preset route; this application can improve injection efficiency and also can improve the injection effect simultaneously, but this application can only carry out the single injection, and the connection can not be dismantled in syringe and pumpback judgement pipe can not realize, and pumpback judgement pipe can not carry out repeated change, consequently can not realize a lot of continuous injections in a plurality of positions of myocardium target tissue.
The patent CN211327463U provides an injection system with a remote feeding function, which includes a feeding cavity, an injection cavity, a pushing assembly and an injection material accommodated in the feeding cavity, wherein an injection needle is arranged at a remote end of the injection system, the injection needle is of a hollow structure, a non-return mechanism and a communication port are arranged in the injection system, the communication port enables the feeding cavity to be in fluid communication with the injection cavity and an inner cavity of the injection needle, and when the injection material in the feeding cavity is input into the injection cavity through the communication port, the pushing assembly moves towards a proximal direction so as to keep a negative pressure state in the injection cavity; the injection material is easy to add and inject relatively thick and is suitable for minimally invasive surgery and minimally invasive interventional operation, the utilization degree of the injection material is high, the injection quantity is controlled accurately, the injection material is convenient to feed in any position in a body in real time, the requirement that the injection material can be fed in multiple times in the body by only using one set of injection system is met, and multiple times of continuous injection cannot be realized.
Therefore, the problems that in the prior art, operation risks caused by large trauma of thoracotomy, low injection efficiency of target tissues, poor treatment effect, leakage of injection, uncontrollable injection amount and the like in the clinical operation process are changed to be urgently solved at present.
Disclosure of Invention
The invention aims to overcome the defects of the prior art, provides an injection system for patients with heart failure, and solves the problems of large wound of open chest surgery, low injection efficiency of target tissues, poor treatment effect, leakage of injection, uncontrollable injection quantity and the like in the clinical operation process in the prior art.
The purpose of the invention is realized by the following scheme:
an injection system comprising an injection assembly comprising one or more injection needles, an injection tube, a diagnostic tube, a detachable connection between the injection tube and the diagnostic tube.
The purpose of the invention can be further realized by the following technical scheme:
in one embodiment, the injection needle is disposed at a distal region of the injection tube or the diagnostic tube; the proximal end area of the injection tube and the proximal end area of the diagnostic tube form a sealed connecting structure at any appointed loading position, the sealed connecting structure is the detachable connecting structure, and the sealed connecting structure enables the diagnostic tube to be repeatedly replaced, so that multiple times of continuous injection of the injection is realized.
In one embodiment, the sealed connection structure includes a sealing structure, a retention structure located at a distal region of the sealing structure, a locking structure located at a proximal region of the sealing structure, a base, and a base mating element in mating connection with the base.
In one embodiment, the injection tube and the diagnosis tube are arranged in parallel side by side or are inserted and sleeved in the same interventional catheter; the distal region of the syringe, the injectate, the distal region of the diagnostic tube, the interventional medium form a communicating structure.
In one embodiment, the injectate is one of a fluid substance or a non-fluid substance; the intervention medium is a fluid substance or a micro-granulated fluid substance, and the intervention medium and the injectate have different molecular structures.
In one embodiment, the syringe contains injectate and the diagnostic tube contains an interventional medium; after the injection tube injects the injectate, part of the injectate is injected into the target tissue, and the rest of the injectate is injected into the target tissue through the intervention medium.
In one embodiment, the interventional catheter is a braided reinforced composite tube capable of bending, resisting radial extrusion, resisting tensile deformation; the outer surface of the interventional catheter is made of a self-lubricating material, and the self-lubricating material comprises one of PTFE, PE, PVP, heparin and PU; the interventional catheter inner surface material does not interact with the injectant and the interventional medium.
In one embodiment, the proximal end of the injection tube is connected with a first propelling device in situ, and the first propelling device is provided with a first non-return structure; the near end of the diagnosis tube is connected with a second propelling device in situ, and a second non-return structure is arranged on the second propelling device; wherein, first contrary structure of ending, second contrary structure of ending is in open or closed state not simultaneously.
In one embodiment, the communicating structure comprises a first precision control structure, the second propelling device is provided with a feeding structure, and the feeding structure comprises a second precision control structure; the precision of the first precision control structure is less than the precision of the second precision control structure.
In one embodiment, the volume V of the first precision control structure 1 Volume V equal to the second precision control structure 2 Thereafter, a volume increment Δ V is given to the second precision control structure, at which time the rest of the injectate is injected into the target tissue by the interventional medium.
In one embodiment, the interventional catheter has a diameter of 20F or less; the interventional catheter has a wall thickness of between 0.03mm and 1 mm.
In a preferred embodiment, the interventional catheter has a wall thickness of [0.1mm,0.3mm ].
In one embodiment, the injection system comprises a guiding and positioning device, wherein the guiding and positioning device comprises an abutting piece arranged at the distal end area of the interventional catheter, a guide block arranged at the distal end area of the injection tube, and a circumferential limiting sleeve arranged on the peripheries of the abutting piece and the guide block; the distal end of the abutting piece is provided with a self-adaptive structure, and the self-adaptive structure can adapt to the myocardial tissue form; the guide block is positioned between the injection needle and the injection tube, the injection needle is anchored on the guide block, and the guide block has stretch-resistant capability.
In one embodiment, a coaxial support structure is provided between the interventional catheter and each of the diagnostic tube and the injection tube and the interventional catheter, and the coaxial support structure enables the diagnostic tube and the injection tube to keep a coaxial state; and the axes of the diagnosis tube and the injection tube are close to the axis of the injection needle.
In one embodiment, a guide track is provided in the abutment to enable the distal portion of the syringe to return to a preset configuration following a preset path.
In one embodiment, the guide block is located on a proximal side of the abutment, and the guide block is provided with a guide hole having a center disposed coaxially with a center of the guide rail.
In one embodiment, the proximal end of the diagnostic tube or the syringe is disposed within an injection track, the center of the injection track being disposed coaxially with the center of the abutment.
In one embodiment, the heart failure treatment system includes a delivery catheter, the guide positioning device being disposed at least partially at a distal region of the delivery catheter, the delivery catheter including a guide catheter and an interventional catheter; when preassembling, the interventional catheter is arranged in the guide catheter and synchronously reaches the myocardial target tissue with the guide catheter, and the distal end of the interventional catheter is vertically abutted against the myocardial surface from the deep inside of the guide catheter.
In one embodiment, the guiding catheter comprises two or more bending sheaths, which ensure that the guiding catheter can perform bending at different angles at different positions.
In one embodiment, the second pushing device comprises an injection judging device, and when the distal end of the injection needle reaches the target tissue position, the injection judging device can be pulled to judge whether the distal end of the injection needle penetrates into the target tissue.
Compared with the prior art, the invention has the advantages that:
1. at present, gel is generally injected to myocardial tissues of heart failure patients by adopting a mode of opening a chest and entering a way in the prior art, the operation mode has great trauma to the patients and long operation time, and only single injection can be realized to target tissues, and multiple continuous injections cannot be realized, so that the injection efficiency is reduced; different from the prior art, in one embodiment of the present invention, the injection assembly includes one or more injection needles, an injection tube, and a diagnostic tube, and a detachable connection structure is provided between the injection tube and the diagnostic tube; when the detachable connection structure is a sealed connection structure, the sealed connection structure can realize the sealing and locking connection of the proximal end area of the injection tube and the proximal end area of the diagnosis tube at any appointed loading position, realize the synchronous pushing, synchronous static and synchronous movement of the injection tube and the diagnosis tube, realize the sealing and locking reversibility of the injection tube and the diagnosis tube, and can be adjusted randomly according to the requirement, thereby realizing the repeated replacement of the diagnosis tube for many times and ensuring the continuous injection of the injection at the target tissue; further, the syringe contains injectate and the diagnostic tube contains an interventional medium; wherein after the injection tube injects the injectant, part of the injectant is injected into the target tissue, the rest of the injectant is injected into the target tissue through the intervention medium, the distal end area of the injection tube, the injectant, the distal end area of the diagnosis tube and the intervention medium form a communication structure, and the intervention medium can ensure that the rest of the injectant is injected into the target tissue, so that the communication structure is free of the intervention medium, and the injection needle can perform the next target injection at the myocardial target tissue.
2. In contrast to the prior art, in one embodiment of the present invention, the injectate is one of a non-fluid substance or a fluid substance; the intervening medium is a fluid substance or a micro-granulated fluid substance; when the injection judging device is pulled to perform the withdrawing judgment, the injection cannot be withdrawn, and the intervention medium can be withdrawn, so that whether the distal end of the injection needle penetrates into the target tissue or not is judged by judging the fluid state of the intervention medium.
3. Different from the prior art, in an embodiment of the present invention, the communication structureThe device comprises a first precision control structure, wherein a feeding structure is arranged on a second propelling device, and the feeding structure comprises a second precision control structure; the precision of the first precision control structure is smaller than that of the second precision control structure; volume V of the first precision control structure 1 Volume V equal to the second precision control structure 2 Then, giving a volume increment DeltaV to the second precision control structure, wherein the rest of the injectate is injected into the target tissue by the intervention medium; can be so that intervene the medium and inject the injection thing into the target tissue completely, when preventing to withdraw and judge, injection thing blocks up injection syringe and diagnostic tube, guarantees that diagnostic tube can repeatedly be changed and carry out the injection of many targets, convenient and fast.
4. Different from the prior art, in an embodiment of the present invention, a coaxial support structure is disposed between the interventional catheter and the diagnostic tube, and between the injection tube and the interventional catheter, and the coaxial support structure enables the diagnostic tube and the injection tube to maintain a coaxial state; and the axes of the diagnosis tube and the injection tube are close to the axis of the injection needle, so that the efficiency of injecting the injection material into the myocardial tissue is improved.
5. Different from the prior art, the distal end of the abutting part is provided with the self-adaptive structure in one embodiment of the invention, and the self-adaptive structure can adapt to the shape of the myocardial tissue, plays a role in buffering and protects the myocardial tissue.
6. Unlike the prior art, in one embodiment of the present invention, the guide positioning device ensures that the distal portion of the syringe is returned to its preset shape following a predetermined path.
Drawings
Fig. 1 is a cross-sectional view showing the overall structure of an injection system according to a first embodiment of the present invention.
FIGS. 2a to 2e are schematic views illustrating a state where the injection needle is ejected from the abutting member according to the first embodiment of the present invention.
Fig. 3 is a schematic structural view illustrating a coaxial supporting structure disposed between a diagnostic tube or an injection tube and an interventional catheter according to an embodiment of the present invention.
Fig. 4a to 4b are schematic views illustrating a sealing connection structure in an injection system according to an embodiment of the present invention.
Fig. 5 a-5 d are schematic views of an injection system of one embodiment of the present invention passing through the femoral artery and conforming through the aortic arch, then passing through the aortic valve site with a first bend, then reaching the left ventricle, and finally reaching the myocardial tissue with its distal end perpendicular with a second bend.
The names of the parts indicated by the numbers in the drawings are as follows: 1-injection component, 11-injection needle, 12-injection tube, 121-injectate, 122-first non-return structure, 123-first propulsion device, 13-diagnosis tube, 131-intervention medium, 132-second non-return structure, 133-second propulsion device, 2-sealed connection structure, 21-sealed structure, 22-limit structure, 23-locking structure, 24-base, 25-base fitting piece, 3-conveying conduit, 31-guiding conduit, 32-intervention conduit, 4-communication structure, 5-guiding and positioning device, 51-abutting part, 511-self-adapting structure, 512-guiding track, 52-guiding block, 53-circumferential limit kit and 6-coaxial support structure.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples.
The proximal end of the invention refers to the end close to the operator, and the distal end refers to the end far away from the operator.
The first embodiment is as follows:
in this embodiment, as shown in fig. 1, an injection system includes an injection assembly 1, where the injection assembly 1 includes one or more injection needles 11, an injection tube 12, and a diagnostic tube 13, and a detachable connection structure is provided between the injection tube 12 and the diagnostic tube 13.
In the present embodiment, as shown in fig. 1 and 4a to 4b, the injection needle 11 is provided at the distal end region of the injection tube 12 or the diagnostic tube 13; the proximal end region of the injection tube 12 and the proximal end region of the diagnostic tube 13 form a sealed connection structure 2 at any designated loading position, the sealed connection structure 2 is the detachable connection structure, and the sealed connection structure 2 enables the diagnostic tube 13 to be repeatedly replaced, so that multiple times of continuous injections of the injectate 121 are realized.
In this embodiment, as shown in fig. 4a to 4b, the sealing connection structure 2 includes a sealing structure 21, a position limiting structure 22 located at the distal end region of the sealing structure 21, a locking structure 23 located at the proximal end region of the sealing structure 21, a base 24, and a base fitting 25 in fitting connection with the base 24.
In this embodiment, as shown in fig. 1, the injection tube 12 and the diagnosis tube 13 are inserted and sleeved in the same interventional catheter 32; the distal end region of the syringe 12, the injectate 121, the distal end region of the diagnostic tube 13, the interventional media 131 form a communicating structure 4.
In this embodiment, the injectate 121 is one of a fluid substance or a non-fluid substance; the intervening medium 131 is a fluid substance or a micro-granulated fluid substance, and the intervening medium 131 has a molecular structure different from that of the injectate 121.
In this embodiment, the syringe 12 contains injectate 121, and the diagnostic tube 13 contains interventional media 131; after the injection tube 12 injects the injectate 121, a part of the injectate 121 is injected into the target tissue, and the rest of the injectate 121 is injected into the target tissue through the intervention medium 131.
In this embodiment, the interventional catheter 32 is a braided reinforced composite tube, which can be bent, resistant to radial extrusion and resistant to tensile deformation; the outer surface of the interventional catheter 32 is made of a self-lubricating material, and the self-lubricating material comprises one of PTFE, PE, PVP, heparin and PU; the material on the inner surface of the interventional catheter 32 does not interact with the injectate 121 and the interventional medium 131.
In this embodiment, as shown in fig. 1 and fig. 4a to 4b, the proximal end of the injection tube 12 is connected to a first pushing device 123 in situ, and a first check structure 122 is disposed on the first pushing device 123; the proximal end of the diagnostic tube 13 is connected with a second propulsion device 133 in situ, and a second non-return structure 132 is arranged on the second propulsion device 133; the first check structure 122 and the second check structure 132 are not in an open or closed state at the same time.
In this embodiment, the communicating structure 4 includes a first precision control structure, the second propelling device is provided with a feeding structure, and the feeding structure includes a second precision control structure; the precision of the first precision control structure is less than the precision of the second precision control structure.
In this embodiment, the volume V of the first precision control structure 1 Volume V equal to the second precision control structure 2 Thereafter, the second precision control structure is given a volume increment Δ V, at which time the remaining injectate 121 is injected into the target tissue by the intervening medium 131.
In this embodiment, the diameter of the interventional catheter 32 is less than or equal to 20F; the interventional catheter 32 has a wall thickness of between 0.03mm and 1 mm.
In this embodiment, the wall thickness of the interventional catheter 32 is [0.1mm,0.3mm ].
In this embodiment, as shown in fig. 1, the injection system includes a guiding and positioning device 5, where the guiding and positioning device 5 includes an abutting piece 51 disposed at the distal end region of the interventional catheter 32, a guiding block 52 disposed at the distal end region of the injection tube 12, and a circumferential limiting sleeve 53 sleeved on the peripheries of the abutting piece 51 and the guiding block 52; wherein, the distal end of the abutting piece 51 is provided with a self-adapting structure 511, and the self-adapting structure 511 can adapt to the shape of the myocardial tissue; wherein the guide block 52 is located between the injection needle 11 and the injection tube 12, the injection needle 11 is anchored on the guide block 52, and the guide block 52 has stretch-resistant capability.
In this embodiment, as shown in fig. 3, a coaxial support structure 6 is disposed between each of the interventional catheter 32 and the diagnostic tube 13, and between each of the injection tube 12 and the interventional catheter 32, and the coaxial support structure 6 keeps the diagnostic tube 13 and the injection tube 12 in a coaxial state; the axial centers of the diagnostic tube 13 and the syringe tube 12 are close to the axial center of the injection needle 11.
In this embodiment, as shown in fig. 2a to 2e, a guide track 512 is provided in the abutting member 51, so that the distal end portion of the syringe 12 can return to the preset configuration according to the preset path.
In this embodiment, the guide block 52 is located on the proximal end side of the abutting member 51, and the guide block 52 is provided with a guide hole having a center coaxially disposed with the center of the guide rail 512.
In this embodiment, the proximal end of the diagnostic tube 13 or the injection tube 12 is disposed within an injection track, the center of which is disposed coaxially with the center of the abutment 51.
In this embodiment, as shown in fig. 1 and fig. 5a to 5d, the heart failure treatment system comprises a delivery catheter 3, the guiding and positioning device 5 is at least partially arranged at the distal end region of the delivery catheter 3, and the delivery catheter 3 comprises a guiding catheter 31 and an interventional catheter 32; when pre-loaded, the interventional catheter 32 is positioned within the guiding catheter 31 and synchronized with the guiding catheter 31 to reach the target tissue of the myocardium, and the distal end of the interventional catheter 32 is positioned from deep within the guiding catheter 31 and perpendicularly against the surface of the myocardium.
In this embodiment, the guiding catheter 31 includes two or more bending sheath tubes, so as to ensure that the guiding catheter 31 can perform bending at different angles at different positions.
In this embodiment, the second pushing device includes an injection judging device, and when the distal end of the injection needle 11 reaches the target tissue position, the injection judging device can be pulled to judge whether the distal end of the injection needle 11 penetrates into the target tissue.
The steps of the operation process of the present embodiment in the operation are as follows (as shown in fig. 1 and fig. 5a to 5 d):
(1) The guiding component comprises two bending-adjusting sheath tubes, passes through the femoral artery, conforms to the aortic arch, passes through the aortic arch, is bent by the first bending-adjusting sheath tube, passes through the aortic valve, reaches the left ventricle, and finally enables the distal end of the guiding component to vertically abut against myocardial tissue through the second bending-adjusting sheath tube;
(2) When the abutting member 51 abuts against the myocardial tissue, the distal end of the injection needle 11 protrudes from the guide rail 512 of the abutting member 51 and penetrates into the myocardial tissue;
(3) Pulling the injection judging device, if the injection judging device returns to the initial position again, the distal end of the injection needle 11 is inserted into the myocardial tissue, and the next operation is continued; if the injection judging means does not return to the initial position again, the injection needle 11 is withdrawn along the original route and the target injection position is searched again;
(4) When the second check structure 132 is closed and the first check structure 122 is opened, the first pushing device delivers the injectate 121 to the target tissue through the injection needle 1131, and a portion of the injectate 121 is driven into the target tissue as shown in fig. 5 a-5 d.
(5) Closing the first non-return structure 122, opening the second non-return structure 132, delivering the intervention medium 131 to the communicating structure 4 through the diagnostic tube 13 by the second pushing device, and injecting the rest of the injectate 121 into the target tissue;
(6) The sealed connection structure 2 is opened, the diagnostic tube 13 is withdrawn or the diagnostic tube 13 is replaced again, and the next target injection of the myocardial target tissue is performed.
The foregoing is only a preferred embodiment of the present invention, and the present invention should not be construed as limited to the embodiments set forth herein, as the description herein will be modified within the scope of the present invention by those skilled in the art based on the teachings herein.
Claims (9)
1. An injection system comprising an injection assembly, characterized in that: the injection assembly comprises one or more injection needles, an injection tube and a diagnosis tube, wherein a detachable connecting structure is arranged between the injection tube and the diagnosis tube, and a sealed connecting structure is formed in the proximal end area of the injection tube and the proximal end area of the diagnosis tube at any specified loading position, and the sealed connecting structure is the detachable connecting structure; wherein the sealed connection structure enables the diagnostic tube to be repeatedly replaced, thereby realizing multiple continuous injections of the injectate.
2. An injection system according to claim 1, wherein: the sealing type connecting structure comprises a sealing structure, a limiting structure positioned at the far end area of the sealing structure, a locking structure positioned at the near end area of the sealing structure, a base and a base fitting piece in fit connection with the base.
3. An injection system according to claim 1, wherein: the injection needle is disposed at a distal region of the injection tube or the diagnostic tube; the injection tube and the diagnosis tube are arranged in parallel or are inserted and sleeved in the same interventional catheter; the distal region of the syringe, injectate, distal region of the diagnostic tube, and intervening medium form a communicating structure.
4. An injection system according to claim 3, wherein: the interventional catheter is a braided reinforced composite tube which can be bent, can resist radial extrusion and can resist tensile deformation; the outer surface of the interventional catheter is made of a self-lubricating material, and the self-lubricating material comprises one of PTFE, PE, PVP, heparin and PU; the interventional catheter inner surface material does not interact with the injectant and the interventional medium.
5. An injection system according to claim 3, wherein: the near end of the injection tube is connected with a first propelling device in situ, and a first non-return structure is arranged on the first propelling device; the near end of the diagnosis tube is connected with a second propelling device in situ, and a second non-return structure is arranged on the second propelling device; wherein, first contrary structure of ending, the contrary structure of second is in the state of opening or closing not simultaneously.
6. An injection system according to claim 5, wherein: the communicating structure comprises a first precision control structure, the second propelling device is provided with a feeding structure, and the feeding structure comprises a second precision control structure; the precision of the first precision control structure is less than the precision of the second precision control structure.
7. An injection system according to claim 6, wherein: volume V of the first precision control structure 1 Volume V equal to the second precision control structure 2 After that, administration is given toAnd the volume increment DeltaV of the second precision control structure is adopted, and the rest of the injectate is injected into the target tissue by the intervention medium.
8. An injection system according to claim 3, wherein: the diameter of the interventional catheter is less than or equal to 20F; the interventional catheter has a wall thickness between 0.03mm and 1 mm.
9. An injection system according to claim 1, wherein: the injection tube contains injectate, and the injectate is one of fluid substance or non-fluid substance; the diagnostic tube contains an intervention medium, the intervention medium is a fluid substance or a tiny granular fluid substance, and the intervention medium and the injectate have different molecular structures;
after the injection tube injects the injectate, part of the injectate is injected into target tissues, and the rest of the injectate is injected into the target tissues through the intervention medium.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2021107911049 | 2021-07-13 | ||
| CN202110791104.9A CN113577504A (en) | 2021-07-13 | 2021-07-13 | Heart failure treatment system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN217548755U true CN217548755U (en) | 2022-10-11 |
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Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110791104.9A Pending CN113577504A (en) | 2021-07-13 | 2021-07-13 | Heart failure treatment system |
| CN202111630646.4A Pending CN114272490A (en) | 2021-07-13 | 2021-12-28 | Heart failure treatment system |
| CN202111630638.XA Pending CN114392459A (en) | 2021-07-13 | 2021-12-28 | Injection system |
| CN202123442539.7U Active CN217548755U (en) | 2021-07-13 | 2021-12-28 | Injection system |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110791104.9A Pending CN113577504A (en) | 2021-07-13 | 2021-07-13 | Heart failure treatment system |
| CN202111630646.4A Pending CN114272490A (en) | 2021-07-13 | 2021-12-28 | Heart failure treatment system |
| CN202111630638.XA Pending CN114392459A (en) | 2021-07-13 | 2021-12-28 | Injection system |
Country Status (2)
| Country | Link |
|---|---|
| CN (4) | CN113577504A (en) |
| WO (1) | WO2023284361A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113577504A (en) * | 2021-07-13 | 2021-11-02 | 宁波迪创医疗科技有限公司 | Heart failure treatment system |
| CN117322450B (en) * | 2023-12-01 | 2024-03-01 | 寿光市金投御达祥农业股份有限公司 | Chicken meat products treatment facility |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4235506A1 (en) * | 1992-10-21 | 1994-04-28 | Bavaria Med Tech | Drug injection catheter |
| DE4408108A1 (en) * | 1994-03-10 | 1995-09-14 | Bavaria Med Tech | Catheter for injecting a fluid or a drug |
| US9278196B2 (en) * | 2011-08-24 | 2016-03-08 | Ablative Solutions, Inc. | Expandable catheter system for vessel wall injection and muscle and nerve fiber ablation |
| US20130053792A1 (en) * | 2011-08-24 | 2013-02-28 | Ablative Solutions, Inc. | Expandable catheter system for vessel wall injection and muscle and nerve fiber ablation |
| WO2017066262A1 (en) * | 2015-10-12 | 2017-04-20 | Swaminathan Jayaraman | System and method for delivery of a therapeutic agent through a catheter |
| CN106983928B (en) * | 2017-04-28 | 2020-07-10 | 宁波迪创医疗科技有限公司 | System for delivering therapeutic agents |
| CN109364349A (en) * | 2018-11-30 | 2019-02-22 | 宁波迪创医疗科技有限公司 | A kind of device for being auxiliarily fixed |
| CN113018645B (en) * | 2019-12-07 | 2021-11-19 | 贵州医科大学 | Blood vessel wall injection catheter system based on electrified expansion medicine bag |
| CN112869849A (en) * | 2021-03-23 | 2021-06-01 | 宁波迪创医疗科技有限公司 | Heart failure treatment system under thoracoscope |
| CN217548756U (en) * | 2021-07-13 | 2022-10-11 | 宁波迪创医疗科技有限公司 | Heart failure treatment system |
| CN113577504A (en) * | 2021-07-13 | 2021-11-02 | 宁波迪创医疗科技有限公司 | Heart failure treatment system |
-
2021
- 2021-07-13 CN CN202110791104.9A patent/CN113577504A/en active Pending
- 2021-12-28 CN CN202111630646.4A patent/CN114272490A/en active Pending
- 2021-12-28 CN CN202111630638.XA patent/CN114392459A/en active Pending
- 2021-12-28 CN CN202123442539.7U patent/CN217548755U/en active Active
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2022
- 2022-04-25 WO PCT/CN2022/089056 patent/WO2023284361A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN113577504A (en) | 2021-11-02 |
| CN114392459A (en) | 2022-04-26 |
| CN114272490A (en) | 2022-04-05 |
| WO2023284361A1 (en) | 2023-01-19 |
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