CN217511289U - Stem cell filtering device - Google Patents
Stem cell filtering device Download PDFInfo
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- CN217511289U CN217511289U CN202221778698.6U CN202221778698U CN217511289U CN 217511289 U CN217511289 U CN 217511289U CN 202221778698 U CN202221778698 U CN 202221778698U CN 217511289 U CN217511289 U CN 217511289U
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Abstract
The utility model provides a stem cell filter equipment relates to stem cell technical field, including filtering main part and receiving flask, the bottom of filtering the main part compresses tightly at the top of receiving flask, filters the main part and passes through locking sealing mechanism and receiving flask fixed mounting, and the top of filtering the main part is equipped with the feed inlet, is provided with the sealing plug in the feed inlet, filters the intracavity and installs the filter stand, installs filtration membrane on the filter stand, installs the supporting mechanism who is used for carrying out the support to the filter stand in the filtration main part, the utility model discloses a filtration membrane mounting structure of quick detach formula has made things convenient for filtration membrane's change, has guaranteed filtration membrane to stem cell's filtration efficiency, has improved the leakproofness between receiving flask and the filtering the main part simultaneously, has avoided the contaminated condition of stem cell to appear.
Description
Technical Field
The utility model belongs to the technical field of the stem cell technique and specifically relates to a stem cell filter equipment is related to.
Background
Before the stem cells are used, the stem cells need to be filtered by using a stem cell filtering device to remove tissue fragments, aggregated cell masses or other impurities which may be present in the stem cells so as to ensure the subsequent use of the stem cells.
The existing stem cell filtering device mainly has the following problems: firstly, a filtering membrane used for filtering stem cells cannot be replaced, the filtering membrane can reduce the filtering efficiency of the stem cells after being used for a long time, bacteria are easy to breed due to the fact that the filtering membrane is not clean in place, and the stem cells are easy to pollute; secondly, the collecting bottle is only simply screwed up on filtering the main part through the screw thread, and the inside sealed effect of filter equipment is relatively poor, and the outside air causes the pollution to stem cells in permeating the collecting bottle through the gap very easily.
Therefore, there is a need for a stem cell filtration device that can solve the above problems.
SUMMERY OF THE UTILITY MODEL
The utility model provides a stem cell filter equipment has adopted the filtration membrane mounting structure of quick detach formula, has made things convenient for filtration membrane's change, has guaranteed filtration membrane to stem cell's filtration efficiency, has improved the leakproofness between receiving flask and the filtration main part simultaneously, has avoided the contaminated condition of stem cell to appear.
The technical scheme of the utility model is realized like this:
a stem cell filtering device comprises a filtering main body, wherein a collecting bottle for receiving filtered stem cells is arranged below the filtering main body, the bottom of the filtering main body is tightly pressed on the top of the collecting bottle, and the filtering main body is fixedly installed with the collecting bottle through a locking sealing mechanism;
a filter cavity is arranged in the filter main body and is communicated with the inside of the collecting bottle through an opening at the bottom, a feed inlet is arranged at the top of the filter main body and is communicated with the filter cavity, a sealing plug is arranged in the feed inlet, a filter frame is arranged in the filter cavity, a filter membrane for filtering stem cells is arranged on the filter frame, and a support mechanism for supporting the filter frame is arranged in the filter main body;
the locking and sealing mechanism comprises an annular cylinder body arranged on the outer wall of the lower end of the filtering main body, the upper end of the collecting bottle is inserted into the annular cylinder body, a plurality of locking blocks are arranged in the annular cylinder body in a sliding manner, each locking block slides along the radial direction of the annular cylinder body, a sealing rubber gasket is coated on each locking block, a sealing groove is annularly arranged on the outer wall of the upper end of the collecting bottle and is matched with the sealing rubber gasket, each locking block is inserted into the sealing groove, each sealing rubber gasket is tightly pressed on the inner wall of the sealing groove, each two adjacent sealing rubber gaskets are abutted together, a first annular seat is rotatably arranged in the annular cylinder body, a plurality of trapezoidal convex blocks are arranged on the inner wall of the first annular seat, and a push plate is abutted on the inclined plane of each trapezoidal convex block, each push plate is fixedly connected with the locking block, a horizontally arranged sliding groove is formed in the side wall of the annular cylinder, an operation push block is installed in the sliding groove in a sliding mode, and the operation push block is fixedly connected with the first annular seat;
the supporting mechanism comprises an annular barrier strip fixed on the inner wall of the filter cavity, a plurality of supporting blocks are arranged below the annular barrier strip, each supporting block is arranged in the filter cavity in a sliding mode along the radial direction of the filter cavity, and the upper end of the filter frame is arranged between the annular barrier strip and the supporting block.
As a preferred technical solution, a protective casing is annularly disposed outside the filtering body, an annular cavity is formed between the protective casing and an outer wall of the filtering body, a second annular seat is installed in the annular cavity, the second annular seat is rotatably connected to the filtering body, one end of each supporting block, which is far away from the filtering frame, extends into the annular cavity, a linkage rod is jointly hinged between each supporting block and the second annular seat, an adjusting screw is fixedly connected to one end of one supporting block, which extends into the annular cavity, extends along a sliding direction of the supporting block, and the adjusting screw is installed on a wall of the protective casing in a threaded connection manner.
As a preferable technical solution, a sealing gasket is fixed at the bottom of the filtering main body, and the bottom of the sealing gasket is pressed against the top of the collecting bottle.
As a preferred technical scheme, an extension spring is arranged between each locking block and the inner wall of the annular cylinder body.
As a preferred technical scheme, be the annular on the inner wall of first annular seat and be fixed with the spacing stupefied of a plurality of, each spacing stupefied all follows the axial extension of first annular seat, be the annular in the annular cylinder and be equipped with the spacing recess of a plurality of, each spacing recess all with spacing stupefied looks adaptation, each spacing stupefied all insert the correspondence in the spacing recess.
By adopting the technical scheme, the beneficial effects of the utility model are that:
as the stem cell filtering device comprises the filtering main body and the collecting bottle, the filtering main body is fixedly arranged with the collecting bottle through the locking sealing mechanism, in the utility model, when the stem cells are required to be filtered, the bottom of the filtering main body is tightly pressed on the top of the collecting bottle, so that the upper end of the collecting bottle is inserted into the annular cylinder at the lower end of the filtering main body, the locking block in the annular cylinder is aligned with the sealing groove on the outer wall of the collecting bottle, then the operation pushing block on the side wall of the annular cylinder body is pushed to slide in the chute, the operation pushing block drives the first annular seat in the annular cylinder body to rotate, the inclined surface of the trapezoidal convex block on the inner wall of the first annular seat pushes the locking block to move, thereby make the latch segment be close to the seal groove gradually and insert in the seal groove, compress tightly the sealed cushion on the latch segment on the inner wall of seal groove, the sealed cushion on two adjacent latch segments also supports and leans on together.
The utility model discloses in, not only utilized the latch segment to filter main part and receiving flask locking fixed, still utilized sealed cushion to seal the gap between filtering main part and the receiving flask, and then improved the receiving flask and filtered the leakproofness between the main part, avoided the external air to enter into the receiving flask through the gap and cause the condition emergence of pollution to the stem cell.
Because the filtering cavity is arranged in the filtering main body, the filtering frame and the supporting mechanism are arranged in the filtering cavity, and the filtering membrane is arranged on the filtering frame, in the utility model, after the filtering work of stem cells is completed and the filtering main body is separated from the collecting bottle, a user rotates the adjusting screw rod outside the filtering main body, the adjusting screw rod is screwed out, the adjusting screw rod drives the supporting block connected with the adjusting screw rod to move outwards, the supporting block can drive the second annular seat to rotate through the linkage rod in the process of moving outwards, the second annular seat can drive the rest supporting blocks to move outwards through the linkage rod, the supporting block can not support the filtering frame any more, the filtering frame can be separated from the opening at the bottom of the filtering main body, the filtering membrane on the filtering frame can be taken down, a new filtering membrane is replaced, the filtering frame is put into the filtering main body, and then the adjusting screw rod is reversely rotated by the user, thereby drive the supporting shoe and inwards move, utilize annular blend stop and supporting shoe to carry out spacing and support to filtering the frame.
The utility model discloses in, adopt the filtration membrane mounting structure of quick detach formula, after accomplishing stem cell's filtration work at every turn, the user all can tear down filtration membrane and wash and change, not only made things convenient for filtration membrane's change, but also avoided influencing the condition appearance of filter effect because of impurity adheres to on filtration membrane to guaranteed filtration membrane to stem cell's filter effect, still avoided the next filtration during operation simultaneously, the attached impurity on the filtration membrane causes the condition of pollution to stem cell to take place, has guaranteed stem cell's quality, has improved the utility model discloses a security.
Because the bottom of filtering the main part is fixed with seal ring, seal ring's bottom compresses tightly in the top of receiving flask the utility model discloses in, seal ring is used for sealing up the gap between filtering main part bottom and the receiving flask top, has improved the leakproofness between filtering main part and the receiving flask, has avoided the outside air to enter into the receiving flask and has caused the condition emergence of pollution to the stem cell.
Because it is that the annular is fixed with the spacing protruding stupefied of a plurality of to be on the inner wall of first annular seat, be the annular in the annular barrel and be equipped with the spacing recess of a plurality of the utility model discloses in, spacing protruding stupefied on the first annular seat inner wall and the mutual interlock of spacing recess on the annular barrel inner wall have played and have carried out spacing effect to first annular seat, avoided taking place to rotate at will because of first annular seat and influence the locking effect of latch segment to the receiving flask, perhaps influence the sealed cushion and take place to the sealed condition of effect between filtering main part and the receiving flask, guaranteed the leakproofness between filtering main part and the receiving flask.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive exercise.
Fig. 1 is a schematic structural view of the present invention;
FIG. 2 is an enlarged view of the structure at A in FIG. 1;
FIG. 3 is an enlarged view of the structure at B in FIG. 1;
FIG. 4 is a schematic cross-sectional view taken along line C-C of FIG. 1;
FIG. 5 is a schematic cross-sectional view taken along line D-D of FIG. 1;
FIG. 6 is a schematic cross-sectional view taken along direction E-E of FIG. 1.
Wherein: 1. a filter body; 2. a collection bottle; 3. a filter chamber; 4. a feed inlet; 5. a sealing plug; 6. a filter frame; 7. a filtration membrane; 8. an annular cylinder; 9. a locking block; 10. sealing the rubber gasket; 11. a sealing groove; 12. a first annular seat; 13. a trapezoidal bump; 14. pushing the plate; 15. a chute; 16. operating the push block; 17. an annular barrier strip; 18. a support block; 19. a protective housing; 20. an annular cavity; 21. a second annular seat; 22. a linkage rod; 23. adjusting the screw rod; 24. a sealing gasket; 25. an extension spring; 26. limiting convex edges; 27. and a limiting groove.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
As shown in figures 1-6 together, a stem cell filtering device comprises a filtering main body 1, a collecting bottle 2 for receiving filtered stem cells is arranged below the filtering main body 1, the bottom of the filtering main body 1 is pressed on the top of the collecting bottle 2, and the filtering main body 1 is fixedly installed with the collecting bottle 2 through a locking sealing mechanism.
The locking and sealing mechanism comprises an annular cylinder body 8 arranged on the outer wall of the lower end of the filtering main body 1, the upper end of the collecting bottle 2 is inserted into the annular cylinder body 8, a plurality of locking blocks 9 are arranged in the annular cylinder body 8 in a sliding manner, each locking block 9 slides along the radial direction of the annular cylinder body 8, each locking block 9 is coated with a sealing rubber pad 10, the outer wall of the upper end of the collecting bottle 2 is provided with a sealing groove 11 in a ring manner, the sealing groove 11 is matched with the sealing rubber pads 10, each locking block 9 is inserted into the sealing groove 11, each sealing rubber pad 10 is tightly pressed on the inner wall of the sealing groove 11, each two adjacent sealing rubber pads 10 are abutted together, a first annular seat 12 is rotatably arranged in the annular cylinder body 8, the inner wall of the first annular seat 12 is provided with a plurality of trapezoidal lugs 13, a push plate 14 is abutted on the inclined plane of each trapezoidal lug 13, each push plate 14 is fixedly connected with the locking block 9, be equipped with the spout 15 that a level set up on the lateral wall of annular barrel 8, slidable mounting has an operation ejector pad 16 in spout 15, operation ejector pad 16 and first annular seat 12 fixed connection the utility model discloses in, it is fixed to have not only utilized latch segment 9 to lock filtration main part 1 and receiving flask 2, has still utilized sealed cushion 10 to seal the gap between filtration main part 1 and the receiving flask 2, and then has improved the leakproofness between receiving flask 2 and the filtration main part 1, has avoided the external air to enter into receiving flask 2 through the gap and has caused the condition of pollution to the stem cell to take place.
The supporting mechanism comprises an annular barrier strip 17 fixed on the inner wall of the filter cavity 3, a plurality of supporting blocks 18 are arranged below the annular barrier strip 17, each supporting block 18 is arranged in the filter cavity 3 in a sliding mode along the radial direction of the filter cavity 3, and the upper end of the filter frame 6 is arranged between the annular barrier strip 17 and the supporting block 18.
Wherein, the outer side of the filter body 1 is annularly provided with a protective shell 19, an annular cavity 20 is formed between the protective shell 19 and the outer wall of the filter body 1, a second annular seat 21 is installed in the annular cavity 20, the second annular seat 21 is rotatably connected with the filter body 1, one end of each supporting block 18, which is far away from the filter frame 6, all extends into the annular cavity 20, a linkage rod 22 is hinged between each supporting block 18 and the second annular seat 21, one end of one of the supporting blocks 18, which extends into the annular cavity 20, is fixedly connected with an adjusting screw 23, the adjusting screw 23 extends along the sliding direction of the supporting block 18, and the adjusting screw 23 is installed on the shell wall of the protective shell 19 in a threaded connection manner.
The utility model discloses in, the filtration membrane 7 mounting structure of quick detach formula is adopted, has not only made things convenient for filtration membrane 7's change, but also has avoided influencing the condition appearance of filtration membrane 7 filter effect because of impurity adheres to on filtration membrane 7 to guaranteed filtration membrane 7 and to the filter effect of stem cell, still avoided the filter work time of next time simultaneously, the condition emergence that the adnexed impurity caused the pollution to the stem cell on the filtration membrane 7.
Moreover, the bottom of filtering main part 1 is fixed with seal ring 24, and seal ring 24's bottom compresses tightly in the top of receiving flask 2 the utility model discloses in, seal ring 24's setting has improved the leakproofness of filtering between main part 1 and the receiving flask 2, has avoided the outside air to enter into in the receiving flask 2 and has caused the condition of pollution to the stem cell to take place.
An extension spring 25 is arranged between each locking block 9 and the inner wall of the annular cylinder 8.
In addition, be the annular on the inner wall of first annular seat 12 and be fixed with the spacing stupefied 26 of a plurality of, each spacing stupefied 26 all follows the axial extension of first annular seat 12, is the annular in the annular barrel 8 and is equipped with the spacing recess 27 of a plurality of, each spacing recess 27 all with spacing stupefied 26 looks adaptation, each spacing stupefied 26 all inserts in corresponding spacing recess 27, the utility model discloses in, each spacing stupefied 26 all with spacing recess 27 interlock each other, played and carried out spacing effect to first annular seat 12, avoided influencing the locking block 9 to receiving flask 2 locking effect because of first annular seat 12 is random rotatory, perhaps influenced sealed cushion 10 and taken place filtering the sealed effect between main part 1 and the receiving flask 2, guaranteed the leakproofness between filtering main part 1 and the receiving flask 2.
The method of the utility model is as follows:
taking out a new filter membrane 7, installing the filter membrane 7 on a filter frame 6, then placing the filter frame 6 into a filter cavity 3 through an opening at the bottom of a filter main body 1, after the top of the filter frame 6 abuts against an annular barrier strip 17, a user screws an adjusting screw 23 inwards, the adjusting screw 23 drives a corresponding supporting block 18 to move towards the direction close to the filter frame 6, the supporting block 18 can drive a second annular seat 21 to rotate through a linkage rod 22 in the moving process, the second annular seat 21 can drive the other linkage rods 22 to rotate, the linkage rods 22 are used for pushing the other supporting blocks 18 to move towards the direction close to the filter frame 6, and the supporting block 18 and the annular barrier strip 17 are used for limiting and supporting the filter frame 6;
secondly, the user takes out the clean collecting bottle 2, aligns the bottom of the filtering main body 1 to the top of the collecting bottle 2, then tightly presses the bottom of the filtering main body 1 to the top of the collecting bottle 2, so that the upper end of the collecting bottle 2 is inserted into the annular cylinder 8, and the locking block 9 is aligned to the sealing groove 11;
thirdly, a user pushes the operation push block 16 to slide in the sliding groove 15 by hand, the operation push block 16 drives the first annular seat 12 to rotate, in the process of rotating the first annular seat 12, the inclined surface of the trapezoidal convex block 13 can push the locking block 9 to move towards the direction close to the sealing groove 11, the locking block 9 is inserted into the sealing groove 11, the sealing rubber pads 10 are tightly pressed on the inner wall of the sealing groove 11, and the sealing rubber pads 10 on two adjacent locking blocks 9 are abutted together;
fourthly, the sealing plug 5 in the feeding hole 4 is pulled out, the stem cells to be filtered are poured into the filtering cavity 3 through the feeding hole 4, the stem cells to be filtered fall into the filtering rack 6 under the action of gravity, the filtering membrane 7 is utilized to filter the stem cells to be filtered, and the filtered stem cells fall into the collecting bottle 2 through the opening at the bottom of the filtering main body 1;
fifthly, after the filtering operation is finished, a user pushes the operation push block 16 with a hand to perform reverse sliding to drive the first annular seat 12 and the trapezoidal convex block 13 to perform reverse sliding, so that the inclined surface of the trapezoidal convex block 13 is separated from the push plate 14, and under the action of the elastic force of the extension spring 25, the locking block 9 and the push plate 14 are driven to move towards the direction far away from the sealing groove 11, so that the locking block 9 and the sealing rubber gasket 10 are separated from the sealing groove 11, and the separation between the collecting bottle 2 and the filtering main body 1 is realized;
in the sixth step, the user can then pour the stem cells in the collection bottle 2 into a suitable container for further processing.
To sum up, the utility model provides a stem cell filter equipment has adopted the filtration membrane 7 mounting structure of quick detach formula, has made things convenient for filtration membrane 7's change, has guaranteed filtration membrane 7 to stem cell's filtration efficiency, has improved the leakproofness between receiving flask 2 and the filtration main part 1 simultaneously, has avoided the contaminated condition of stem cell to appear.
The above description is only for the preferred embodiment of the present invention, and should not be taken as limiting the invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (5)
1. A stem cell filtering device is characterized by comprising a filtering main body, wherein a collecting bottle for receiving filtered stem cells is arranged below the filtering main body, the bottom of the filtering main body is tightly pressed on the top of the collecting bottle, and the filtering main body is fixedly installed with the collecting bottle through a locking sealing mechanism;
a filter cavity is arranged in the filter main body and is communicated with the interior of the collecting bottle through an opening at the bottom, a feed inlet is arranged at the top of the filter main body and is communicated with the filter cavity, a sealing plug is arranged in the feed inlet, a filter frame is arranged in the filter cavity, a filter membrane for filtering stem cells is arranged on the filter frame, and a supporting mechanism for supporting the filter frame is arranged in the filter main body;
the locking and sealing mechanism comprises an annular cylinder body arranged on the outer wall of the lower end of the filtering main body, the upper end of the collecting bottle is inserted into the annular cylinder body, a plurality of locking blocks are arranged in the annular cylinder body in a sliding manner, each locking block slides along the radial direction of the annular cylinder body, a sealing rubber gasket is coated on each locking block, a sealing groove is annularly arranged on the outer wall of the upper end of the collecting bottle and is matched with the sealing rubber gasket, each locking block is inserted into the sealing groove, each sealing rubber gasket is tightly pressed on the inner wall of the sealing groove, each two adjacent sealing rubber gaskets are abutted together, a first annular seat is rotatably arranged in the annular cylinder body, a plurality of trapezoidal convex blocks are arranged on the inner wall of the first annular seat, and a push plate is abutted on the inclined plane of each trapezoidal convex block, each push plate is fixedly connected with the locking block, a horizontally arranged sliding groove is formed in the side wall of the annular cylinder, an operation push block is installed in the sliding groove in a sliding mode, and the operation push block is fixedly connected with the first annular seat;
the supporting mechanism comprises an annular barrier strip fixed on the inner wall of the filter cavity, a plurality of supporting blocks are arranged below the annular barrier strip, each supporting block is arranged in the filter cavity in a sliding mode along the radial direction of the filter cavity, and the upper end of the filter frame is arranged between the annular barrier strip and the supporting block.
2. The stem cell filtering device according to claim 1, wherein a protective casing is annularly arranged on an outer side of the filtering body, an annular cavity is formed between the protective casing and an outer wall of the filtering body, a second annular seat is installed in the annular cavity, the second annular seat is rotatably connected with the filtering body, one end of each supporting block, which is far away from the filtering frame, extends into the annular cavity, a linkage rod is jointly hinged between each supporting block and the second annular seat, an adjusting screw is fixedly connected to one end of each supporting block, which extends into the annular cavity, extends along a sliding direction of the supporting block, and the adjusting screw is threadedly installed on a wall of the protective casing.
3. The stem cell filtering device as claimed in claim 2, wherein the bottom of the filtering body is fixed with a sealing gasket, and the bottom of the sealing gasket is pressed against the top of the collecting bottle.
4. The stem cell filtration device according to claim 3, wherein a tension spring is installed between each locking block and the inner wall of the annular cylinder.
5. The stem cell filtering device according to claim 4, wherein a plurality of limiting ribs are annularly fixed on the inner wall of the first annular seat, each limiting rib extends along the axial direction of the first annular seat, a plurality of limiting grooves are annularly arranged in the annular cylinder, each limiting groove is matched with the limiting ribs, and each limiting rib is inserted into the corresponding limiting groove.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221778698.6U CN217511289U (en) | 2022-07-12 | 2022-07-12 | Stem cell filtering device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221778698.6U CN217511289U (en) | 2022-07-12 | 2022-07-12 | Stem cell filtering device |
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| Publication Number | Publication Date |
|---|---|
| CN217511289U true CN217511289U (en) | 2022-09-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221778698.6U Active CN217511289U (en) | 2022-07-12 | 2022-07-12 | Stem cell filtering device |
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| Country | Link |
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| CN (1) | CN217511289U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117586859A (en) * | 2023-11-28 | 2024-02-23 | 上海多宁生物科技股份有限公司 | Stem cell conditioned medium purification device and application method thereof |
-
2022
- 2022-07-12 CN CN202221778698.6U patent/CN217511289U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117586859A (en) * | 2023-11-28 | 2024-02-23 | 上海多宁生物科技股份有限公司 | Stem cell conditioned medium purification device and application method thereof |
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