CN217491939U - Biological magnetic bead recovery ultrasonic cleaning device - Google Patents
Biological magnetic bead recovery ultrasonic cleaning device Download PDFInfo
- Publication number
- CN217491939U CN217491939U CN202123275702.5U CN202123275702U CN217491939U CN 217491939 U CN217491939 U CN 217491939U CN 202123275702 U CN202123275702 U CN 202123275702U CN 217491939 U CN217491939 U CN 217491939U
- Authority
- CN
- China
- Prior art keywords
- magnetic
- cleaning tank
- cleaning
- ultrasonic
- rod sleeve
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Cleaning By Liquid Or Steam (AREA)
Abstract
The utility model discloses a biomagnetic bead recovery ultrasonic cleaning device, which comprises a cleaning tank without a cover and in a rectangular shape, wherein the side wall of the cleaning tank is provided with a water inlet which is communicated with an automatic liquid adding device; an ultrasonic device is arranged on the side wall of the cleaning tank, and a water outlet is arranged at the bottom of the cleaning tank; a magnetic rod sleeve is covered on the upper part of the cleaning tank, and a plurality of magnetic rods are arranged in the magnetic rod sleeve; the upper part of the magnetic rod sleeve is lapped with a horizontally arranged connecting magnet, and the other end of the connecting magnet is fixedly connected with an automatic lifting device. The utility model discloses a magnetic bead retrieves ultrasonic cleaning's flow ization, mechanization, has improved production efficiency, has avoided human source pollution.
Description
Technical Field
The utility model relates to the field of biotechnology, more specifically relate to a biological magnetic bead retrieves ultrasonic cleaning device.
Background
Magnetic Nanoparticles/Magnetic Nanoparticles (MNPs) are novel materials which have been developed rapidly and have great application value in recent years, and generally are nanoscale particles composed of metal oxides such as iron, cobalt, nickel and the like,due to iron oxide (Fe) 3 O 4 ) The superparamagnetic iron oxide magnetic nanoparticles are the most magnetic of natural minerals on the earth, and have high biological safety (materials such as cobalt, nickel and the like have biological toxicity), so the superparamagnetic iron oxide magnetic nanoparticles are the most common in numerous fields of modern science, such as biomedicine, magnetofluid, catalysis, nuclear magnetic resonance imaging, data storage, environmental protection and the like. The magnetic nanoparticles have a series of unique and superior physical and chemical properties such as magnetic guidance, biocompatibility, small-size effect, surface effect and the like, can simplify a complicated traditional experiment method, shorten the experiment time, and are a novel high-efficiency reagent.
The biomagnetic beads refer to superparamagnetic microspheres with fine particle sizes, and generally have super-strong paramagnetism. Can be rapidly gathered in the magnetic field and can be uniformly dispersed after leaving the magnetic field to help magnetic separation. Secondly, the magnetic particles have proper and small-difference particle sizes, so that the magnetic responsiveness is strong enough and the magnetic particles cannot settle. And thirdly, the magnetic nano-particles have abundant surface active groups so as to be coupled with biochemical substances and realize the separation from the sample to be detected under the action of an external magnetic field. Compared with the traditional separation method, the magnetic beads are used for separating complex components of the biochemical sample, separation and enrichment can be carried out simultaneously, the separation speed and the enrichment efficiency are effectively improved, and meanwhile, the sensitivity of analysis and detection is greatly improved.
After the production of the magnetic beads is completed, the magnetic beads need to be recovered from the preparation solution, and the magnetic beads with weak magnetism are screened out and cleaned. The traditional manual recovery has the defects of complicated steps and long time consumption. Therefore, an ultrasonic cleaning device for biomagnetic bead recovery is needed.
SUMMERY OF THE UTILITY MODEL
The utility model discloses the technical problem that needs to solve provides a biological magnetic bead retrieves ultrasonic cleaning device to solve the problem of manual magnetic bead inefficiency of retrieving, in order to improve the production efficiency of magnetic bead.
In order to solve the technical problem, the utility model adopts the following technical proposal.
The ultrasonic cleaning device for the recovery of the biological magnetic beads comprises a cleaning tank which is uncovered and rectangular and is used for containing prepared liquid and magnetic beads to be recovered, wherein a water inlet is formed in the side wall of the cleaning tank and is communicated with an automatic liquid adding device for supplementing the prepared liquid and the magnetic beads to be recovered; an ultrasonic device for cleaning magnetic beads is arranged on the side wall of the cleaning tank, and a water outlet for discharging waste liquid is arranged at the bottom of the cleaning tank; a magnetic rod sleeve which can extend into the cleaning tank is covered above the cleaning tank, and a plurality of vertically arranged magnetic rods are arranged in the magnetic rod sleeve; and a horizontally arranged connecting magnet is lapped above the magnetic rod sleeve, and the other end of the connecting magnet is fixedly connected with an automatic lifting device used for controlling the connecting magnet to move up and down.
According to the further optimized technical scheme, the automatic lifting device comprises a base arranged on the workbench, and an air cylinder is fixedly arranged on the base; and a horizontally arranged connecting rod is fixedly connected to a telescopic rod of the cylinder.
Further optimize technical scheme, connecting magnet and connecting rod fixed connection.
Due to the adoption of the technical scheme, the utility model has the following technical progress.
The utility model provides a biomagnetic bead recovery ultrasonic cleaning device, which controls the magnetic bar to move up and down through an automatic lifting device, and realizes the purpose of making liquid by the magnetic bar in and out; an ultrasonic device is arranged to clean the magnetic beads, the cleaning device can repeatedly clean the magnetic beads until the use standards of a laboratory are met, and the magnetic beads with better magnetism are recovered from a large amount of preparation liquid. The utility model discloses a magnetic bead retrieves ultrasonic cleaning's flow, mechanization, has improved production efficiency, has avoided human-derived pollution.
Drawings
FIG. 1 is a schematic view of the present invention;
wherein: 1. washing tank, 2, automatic lifting device, 21, base, 22, cylinder, 23, connecting rod, 24, connecting magnet, 3, magnetic rod, 4, magnetic rod sleeve, 5, water inlet, 6, water outlet, 7, automatic liquid feeding device, 8 and ultrasonic device.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.
The ultrasonic cleaning device for recycling biomagnetic beads is shown in a combined figure 1 and comprises a cleaning tank 1, an automatic lifting device 2, a base 21, a cylinder 22, a connecting rod 23, a connecting magnet 24, a magnetic rod 3, a magnetic rod sleeve 4, a water inlet 5, a water outlet 6, an automatic liquid adding device 7 and an ultrasonic device 8.
The washing tank 1 is rectangular and has no cover, and is used for containing the prepared liquid and the magnetic beads to be recovered.
A water inlet 5 is formed in the side wall of the cleaning tank 1, the water inlet 5 is communicated with an automatic liquid adding device 7, and the automatic liquid adding device 7 is used for supplementing prepared liquid and magnetic beads to be recovered in time. An ultrasonic device 8 is arranged on the side wall of the cleaning tank 1 and used for cleaning magnetic beads. The bottom of the cleaning tank 1 is provided with a water outlet 6 for discharging the cleaned waste liquid.
The upper cover of the cleaning tank 1 is provided with a magnetic rod sleeve 4, and the magnetic rod sleeve 4 can extend into the cleaning tank 1 to ensure that the magnetic rod 3 is fully contacted with the prepared liquid. Be equipped with the magnetic rod 3 of a plurality of vertical settings in the magnetic rod cover 4, the top overlap joint of magnetic rod cover 4 has the connecting magnet 24 of level setting, and the other end fixedly connected with automatic lifting device 2 of connecting magnet 24, through the up-and-down motion of automatic lifting device 2 control connecting magnet 24, and then realizes the business turn over of magnetic rod 3 in the finished liquid.
The utility model discloses when the in-service use, make the magnetic bead into liquid and add washing tank 1 to erect bar magnet cover 4 in washing tank 1, then open ultrasonic device 8, begin to carry out the ultrasonic washing. After washing for a period of time, controlling the magnetic rod 3 to descend into the magnetic rod sleeve 4 through the automatic lifting device 2, stopping for a period of time, collecting magnetic beads for a period of time, then opening the water outlet 6, and discharging waste liquid.
Cleaning solution is added into the cleaning tank 1, the magnetic rod 3 is controlled to lift by the automatic lifting device 2, and then ultrasonic cleaning is carried out again. After washing for a period of time, the magnetic rod 3 is controlled by the automatic lifting device 2 to descend into the magnetic rod sleeve 4, one end of the magnetic rod is stopped, magnetic beads are collected for a period of time, then the water outlet 6 is opened, and waste liquid is discharged.
Adding another washing solution, and repeating the steps until the magnetic beads are washed clean.
Claims (3)
1. Biological magnetic bead retrieves ultrasonic cleaning device, its characterized in that: the device comprises a cleaning tank (1) which is uncovered and rectangular and is used for containing prepared liquid and magnetic beads to be recovered, wherein a water inlet (5) is formed in the side wall of the cleaning tank (1), and the water inlet (5) is communicated with an automatic liquid adding device (7) used for supplementing the prepared liquid and the magnetic beads to be recovered; an ultrasonic device (8) for cleaning magnetic beads is arranged on the side wall of the cleaning tank (1), and a water outlet (6) for discharging waste liquid is arranged at the bottom of the cleaning tank (1); a magnetic rod sleeve (4) which can extend into the cleaning tank (1) is covered above the cleaning tank (1), and a plurality of vertically arranged magnetic rods (3) are arranged in the magnetic rod sleeve (4); a horizontally arranged connecting magnet (24) is lapped above the magnetic rod sleeve (4), and the other end of the connecting magnet (24) is fixedly connected with an automatic lifting device (2) used for controlling the connecting magnet (24) to move up and down.
2. The ultrasonic cleaning device for recycling biomagnetic beads according to claim 1, wherein: the automatic lifting device (2) comprises a base (21) arranged on the workbench, and a cylinder (22) is fixedly arranged on the base (21); and a horizontally arranged connecting rod (23) is fixedly connected to a telescopic rod of the air cylinder (22).
3. The ultrasonic cleaning device for recycling biomagnetic beads according to claim 2, wherein: the connecting magnet (24) is fixedly connected with the connecting rod (23).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123275702.5U CN217491939U (en) | 2021-12-24 | 2021-12-24 | Biological magnetic bead recovery ultrasonic cleaning device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123275702.5U CN217491939U (en) | 2021-12-24 | 2021-12-24 | Biological magnetic bead recovery ultrasonic cleaning device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN217491939U true CN217491939U (en) | 2022-09-27 |
Family
ID=83344377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202123275702.5U Active CN217491939U (en) | 2021-12-24 | 2021-12-24 | Biological magnetic bead recovery ultrasonic cleaning device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN217491939U (en) |
-
2021
- 2021-12-24 CN CN202123275702.5U patent/CN217491939U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN209188997U (en) | A kind of garbage sorting equipment | |
| CN102836774B (en) | Coal floating and sinking device and method | |
| CN103583455B (en) | A kind of cyclone type screen filtration system and filter method thereof | |
| CN210617030U (en) | Micro-plastic flotation device | |
| CN207427835U (en) | Planktonic organism and particle matter collection device suitable for Large River | |
| CN107593631A (en) | A kind of planktonic organism and particle matter collection device and application suitable for Large River | |
| CN105771908B (en) | A kind of magnetic silica core-shell composite material and preparation method thereof for heavy metal adsorption | |
| CN206881298U (en) | One kind sedimentation coastal waters phytoplankton device | |
| CN108435405A (en) | A kind of automatic float-sink test device of coal | |
| CN110237821A (en) | A kind of ferromagnetism nanometer particle preparation and its application in the extraction of micro- plastics and removal | |
| CN108619769A (en) | A kind of suction filtration system and solid-liquid separating method being suitable for separation of solid and liquid | |
| CN105665121A (en) | Multi-level beneficiation device and application thereof | |
| CN217491939U (en) | Biological magnetic bead recovery ultrasonic cleaning device | |
| CN216654947U (en) | Separation and waste liquid recovery device of micro-plastic in soil or sediment | |
| CN208944542U (en) | A kind of minerals screening plant | |
| CN109870326A (en) | Based on field sampling portable suspension particle sampling device and its method of sampling on plateau | |
| CN203076079U (en) | Magnetic floatation separation device with microbubble generators | |
| CN203618581U (en) | Swirling flow type screen filter system | |
| CN110530696A (en) | A kind of micro- apparatus for separating plastic chips and screening technique for solid sample | |
| CN103333880A (en) | Method for harvesting microalgae with magnetic separator | |
| CN205673068U (en) | Abrasive material Grading Overflow settles comprehensive classification device | |
| CN204412441U (en) | A kind of old and useless battery roasting material concentration equipment | |
| CN207703529U (en) | Based on field sampling portable suspension particle sampling device on plateau | |
| CN109663665A (en) | Spiral laboratory Armco magnetic iron automatic electric magnetic separation instrument and magnetic selection method | |
| CN203513759U (en) | Size mixing and desanding device for copper anode slime |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |