CN217442969U

CN217442969U - Multifunctional automatic post-processing device based on biological fluid sample filtration

Info

Publication number: CN217442969U
Application number: CN202220988131.5U
Authority: CN
Inventors: 揣磊; 李宁; 谢新刚; 高占岭; 胡克; 邓宛梅
Original assignee: Beijing Labtech Instruments Co ltd
Current assignee: Beijing Labtech Instruments Co ltd
Priority date: 2022-04-26
Filing date: 2022-04-26
Publication date: 2022-09-16
Anticipated expiration: 2032-04-26

Abstract

The utility model relates to a multi-functional automatic post processing apparatus based on organism liquid sample filters, its characterized in that: a storage component is arranged in the sliding component, the sliding component is also connected with the functional component in a sliding way, the functional component adjusts the relative position with the storage component through sliding, the screw rod motor is used for the horizontal movement of the sliding platform, the guide rod cylinder is used for the axial telescopic movement of the vacuum chuck and the compression column, the spray head of the code spraying machine is horizontally moved for information spray printing, the feeding cylinder is in contact connection with the code spraying packing paper for the floating support of the code spraying packing paper, the utility model provides a problem that the treatment effeciency is low, solved the problem that easily causes the sample loss, solved the problem that easily produces and remain and cross contamination, solved the problem that can't accomplish the automatic synchronization of information and interacted, shifted on line, solved the problem that sample preparation index is uncontrollable in the experimentation, not up to standard.

Description

Multifunctional automatic post-processing device based on biological fluid sample filtration

Technical Field

The utility model relates to a multi-functional automatic aftertreatment device based on organism liquid sample filters, wherein the organism body fluid specifically includes liquid such as urine, saliva, people's milk, blood.

Background

Domestic hospitals have a large amount of biological body fluid tests every year, but biological body fluid samples cannot be stored for a long time in a normal environment, and a large amount of valuable samples are disposed. At present, the domestic biological body fluid has high storage cost and great technical difficulty and occupies a large amount of space, so that a biological body fluid sample library cannot be established. If a method is available for storing biological fluid samples and establishing a biological fluid sample library which can be effectively stored for a long time, the biological fluid samples can be extracted and analyzed at any time, and the method has very important significance for screening and preventing diseases, accurately diagnosing and predicting individual diseases and improving the health of the whole people. More researchers research now and pass through the manual suction filtration of filtration membrane with biological body fluid, remain the protein in the biological body fluid on filtration membrane, dry film biological body liquid sample is made to the filtration membrane stoving, and after the vacuum plastic envelope, reliable preservation can be realized for a long time to supply follow-up analysis to use. However, in the manual suction filtration mode, the same fixed membrane device can cause cross contamination when the adsorption filter membrane is taken out, and the problem that the sample information and the actual recorded information are disordered and asymmetrical easily occurs if the sample amount is large.

SUMMERY OF THE UTILITY MODEL

The utility model provides a multi-functional automatic post processing apparatus based on organism liquid sample filters has solved the problem that the treatment effeciency is low, has solved the problem that easily causes the sample loss, has solved the problem that easily produces and remains and cross contamination, has solved the problem that can't accomplish the automatic synchronization of information and is interactive, shift on line, has solved the problem that sample preparation index is uncontrollable in the experimentation, not up to standard.

In order to realize the purpose, the utility model discloses a technical scheme is:

the utility model provides a multi-functional automatic post processing apparatus based on organism liquid sample filters which characterized in that: a storage component is arranged in the sliding component, the sliding component is also connected with a functional component in a sliding manner, and the functional component can adjust the relative position with the storage component through sliding;

the sliding assembly comprises a screw motor, a linear guide rail sliding block component and a sliding platform, the linear guide rail sliding block component is connected with the sliding platform in a sliding mode, the sliding platform is further in transmission connection with the screw motor, and the screw motor is used for enabling the sliding platform to move horizontally;

the functional component comprises a container bottom plate, a guide rod cylinder and an ink-jet printer nozzle, the container bottom plate is fixedly connected to the sliding platform, the guide rod cylinder is fixed on the container bottom plate through a cylinder mounting plate, the guide rod cylinder is used for axial telescopic movement of the vacuum chuck and the compression leg, the ink-jet printer nozzle is fixed on the container bottom plate through a nozzle fixing seat, and the ink-jet printer nozzle is used for information jet printing through horizontal movement;

storage component includes feed cylinder and diaphragm collecting vessel, the feed cylinder passes through the sliding block and is connected with spouting a yard packing paper contact, supplies spout a yard packing paper floating support, supply the step-by-step gliding of filter screen support through the piston in the diaphragm collecting vessel.

The multi-functional automatic post-processing apparatus based on biological fluid sample filters, wherein: the sliding assembly further comprises a bottom plate, vertical plates and a top plate, the bottom plate is fixedly connected with the top plate through the pair of vertical plates, the lead screw motor is arranged on the vertical plates, the linear guide rail sliding block component is arranged on the top plate, and the top plate is provided with an image recognition camera.

The multi-functional automatic post-processing apparatus based on biological fluid sample filters, wherein: the bottom plate can be fixed or detached through rotation of the pair of butterfly bolts, fulcrum step screws are arranged on two sides of the bottom plate respectively, the fulcrum step screws on one side are rotating shafts, and the fulcrum step screws on the other side are positioned by rotating angles.

The multi-functional automatic post-processing apparatus based on biological fluid sample filters, wherein: the guide rod cylinder with the compression leg transmission is connected, the bottom of compression leg is inside to be set up vacuum chuck, vacuum chuck with the compression leg terminal surface flushes, vacuum chuck and vacuum pump intercommunication.

The multi-functional automatic post-processing apparatus based on biological fluid sample filters, wherein: the storage assembly further comprises a double-cavity base, the double-cavity base is fixedly supported through a side supporting plate, and a small cavity and a large cavity are arranged in the double-cavity base in a separated mode;

the feeding cylinder is arranged below the small cavity, the code spraying packing paper is arranged in the small cavity, a pluggable baffle is arranged at the top end of the code spraying packing paper, the top end of the baffle is in contact with a fixed baffle, and the fixed baffle is fixed on the surface of the top end of the double-cavity base;

the large cavity is internally provided with the membrane collecting tank, and the inner wall of the membrane collecting tank is in contact connection with the piston through an O-shaped ring.

The utility model has the advantages that: the problem of the treatment effeciency low is solved, the problem that easily causes the sample loss has been solved, the problem that easily produces residue and cross contamination has been solved, the problem that can't accomplish the automatic synchronization online interaction of information, shift has been solved, sample preparation index is uncontrollable in the experimentation, problem not up to standard has been solved.

Drawings

Fig. 1 is a block diagram of a multi-functional automatic post-processing apparatus based on biological fluid sample filtration.

Fig. 2 is a view of the slide module.

Fig. 3 is a functional component composition diagram.

FIG. 4 is a diagram of a memory component.

Fig. 5 is a schematic diagram of the device for the paper packing and code spraying process.

Fig. 6 is a schematic diagram of the adsorption paper-taking process of the device.

FIG. 7 is a schematic diagram of the device for separating, storing and collecting sample membranes.

Description of reference numerals: 1-a membrane adaptor; 2-an image recognition camera; 100-a sliding assembly; 101-a base plate; 102-wing bolts; 103-fulcrum step screw; 104-a vertical plate; 105-a lead screw motor; 106-top plate; 107-linear guide slider parts; 108-a sliding platform; 200-functional components; 201-containerizing a bottom plate; 202-vacuum chuck; 203-pressing column; 204-cylinder mounting plate; 205-guide rod cylinder; 206-nozzle fixing seat; 207-inkjet printer nozzle; 300-a storage component; 301-a dual chamber base; 302-a feed cylinder; 303-side support plate; 304-a slider; 305-code spraying packing paper; 306-a baffle plate; 307-fixed baffle; 308-a membrane collection tank; 309-piston; 310-O-ring.

Detailed Description

As shown in fig. 1, the present invention provides a multifunctional automatic post-processing device based on biological fluid sample filtration, which comprises a sliding component 100, a functional component 200 and a storage component 300;

the storage component 300 is arranged in the sliding component 100, the sliding component 100 is also connected with the functional component 200 in a sliding manner, and the functional component 200 is adjusted to be in relative position with the storage component 300 through sliding.

As shown in fig. 2, the sliding assembly 100 includes a bottom plate 101, a vertical plate 104, a lead screw motor 105, a top plate 106, a linear guide slider part 107 and a sliding platform 108;

the bottom plate 101 is fixedly connected with the top plate 106 through a pair of vertical plates 104, the lead screw motor 105 is arranged on the vertical plate 104, the linear guide rail slider part 107 is arranged on the top plate 106, the linear guide rail slider part 107 is connected with the sliding platform 108 in a sliding manner, the lead screw motor 105 is in transmission connection with the sliding platform 108 through a lead screw nut, the lead screw motor 10 enables the sliding platform 108 to move in the horizontal direction through forward rotation or reverse rotation, and the top plate 106 is provided with an image recognition camera 2;

the sliding assembly is characterized in that a pair of butterfly bolts 102 is arranged on the bottom plate 101 in a penetrating mode, the bottom plate 101 can be quickly fixed or detached by rotating the butterfly bolts 102, two fulcrum step screws 103 are respectively arranged on two sides of the bottom plate 101, the butterfly bolts 102 are manually and quickly detached, the sliding assembly can rotate along the fulcrum step screws 103 on one side as rotating shafts, and the fulcrum step screws 103 on the other side are used for positioning during rotary reset.

As shown in fig. 3, the functional assembly 200 includes a container bottom plate 201, a vacuum chuck 202, a pressing column 203, a guide rod cylinder 205 and an inkjet printer head 207;

the packaging plate 201 is fixedly connected with the sliding platform 108, the guide rod cylinder 205 is fixed on the packaging plate 201 through a cylinder mounting plate 204, the guide rod cylinder 205 is in transmission connection with the compression leg 203, the vacuum chuck 202 is embedded in the bottom end of the compression leg 203, the guide rod cylinder 205 can enable the vacuum chuck 202 and the compression leg 203 to move in an axially telescopic manner, the vacuum chuck 202 is flush with the end face of the compression leg 203, the vacuum chuck 202 is communicated with a vacuum pump, the vacuum chuck 202 further absorbs the code spraying packing paper 305 through vacuum, the compression leg 203 can separate the membrane adapter 1 through the thrust of the guide rod cylinder 205, the separated filter screen support is placed in the membrane collecting tank 308, the code spraying machine nozzle 207 is fixed on the packaging plate 201 through a nozzle fixing seat 206, and the code spraying machine nozzle 207 moves horizontally, and dynamic spray printing of the sample membrane information is realized by receiving a code spraying instruction of an upstream controller.

As shown in fig. 4, the storage assembly 300 includes a dual chamber base 301, a feed cylinder 302, and a diaphragm collection tank 308;

the double-cavity base 301 is fixedly supported by a side support plate 303, and a small cavity 311 and a large cavity 312 are arranged in the double-cavity base 301 in a separated mode;

the feeding cylinder 302 is arranged below the small cavity 311, the code-spraying packing paper 305 is arranged in the small cavity 311, the feeding cylinder 302 is in contact connection with the code-spraying packing paper 305 through a sliding block 304 and is used for floating support of the code-spraying packing paper 305, the top end of the code-spraying packing paper 305 is provided with a pluggable baffle 306, the top end of the baffle 306 is in contact with a fixed baffle 307, and the fixed baffle 307 is fixed on the surface of the top end of the double-cavity base 301;

set up in big chamber 312 diaphragm holding tank 308, the inner wall of diaphragm holding tank 308 passes through O type circle 310 and is connected with piston 309 contact to produce appropriate frictional force, pass through in the diaphragm holding tank 308 the piston 309 makes the filter screen support of separation step-by-step gliding, through the promotion of adding up the piston 309 is step-by-step gliding, makes the collection the regular and orderly arrangement of filter screen support is in diaphragm holding tank 308.

The code spraying process of the packing paper is described with reference to fig. 1 and 5, fig. 1 is an initial state of the device, the screw motor 105 is started and rotates in the forward direction to drive the sliding platform 108 to move towards one side close to the screw motor 105, the movement of the sliding platform 108 is finished, the device is as shown in fig. 5, the code spraying action is started to be executed by the code spraying machine nozzle 207 at a preset point in the moving process, the content to be sprayed and printed is sprayed and printed on the code spraying packing paper 305, the code spraying action is finished before the movement of the sliding platform 108 is finished, and the code spraying process is a dynamic code spraying process.

The process of absorbing and picking up the paper is described with reference to fig. 1, fig. 5, and fig. 6, after the inkjet printing operation is completed, the state of the apparatus is as shown in fig. 5, the lead screw motor 105 is started and rotates reversely to drive the sliding platform 108 to move to the side away from the lead screw motor 105, when the sliding platform 108 finishes moving, the apparatus is as shown in fig. 1, the guide rod cylinder 205 is started to move forward to drive the vacuum chuck 202 to move downward and contact with the inkjet printing packing paper 305, and simultaneously, the vacuum pump is started to make the vacuum chuck 202 have negative pressure and absorb the inkjet printing packing paper 305, at this time, the apparatus is as shown in fig. 6, the guide rod cylinder 205 moves reversely, the inkjet printing packing paper 305 is taken out by using the vacuum chuck 202, at this time, the process of absorbing and picking up the paper is completed, and the apparatus is as shown in fig. 1.

Describing the separation of the membrane adapter 1 and the collection of the filter screen bracket with reference to fig. 1, 5 and 7, after the action process of absorbing and taking paper is completed, the state of the device is as shown in fig. 1, the screw rod motor 105 is started and rotates forward to drive the sliding platform 108 to move to the side close to the screw rod motor 105, when the movement is completed, the state of the device is as shown in fig. 5, the guide rod cylinder 205 is started to move forward to drive the vacuum chuck 202 and the press column 203 to move simultaneously, the press column 203 realizes the separation of the membrane adapter 1 by using the thrust of the guide rod cylinder 205, the filter screen bracket is placed on the piston 309 in the membrane collection tank 308, the piston 309 slides down step by step, simultaneously, the vacuum pump is turned off to separate the code-spraying packing paper 305 from the vacuum chuck 202, and the code-spraying packing paper 305 is left above the sample membrane in the filter screen bracket, at this time, as shown in fig. 7, the guide rod cylinder 205 moves in the reverse direction, and the lead screw motor 105 rotates in the reverse direction, so as to drive the sliding platform 108 to move away from the lead screw motor 105, and return to the initial state of the device, at this time, the stop position of the device is shown in fig. 1.

In the separation process of the membrane adapter 1, the device always keeps in direct contact with the sample membrane and is the code-spraying packing paper 305 corresponding to the membrane, so that any part of the device is not in direct contact with the sample membrane, the risk of cross contamination is fundamentally avoided, after the device is reset, the top plate 106 is provided with the image recognition camera 2, the content of the code-spraying packing paper 305 remained above the sample membrane after each separation can be verified and compared, the complete, accurate and clear sample information content is ensured, and the long-term storage is facilitated.

The utility model has the advantages that:

the problem of the treatment effeciency low is solved, the problem that easily causes the sample loss has been solved, the problem that easily produces residue and cross contamination has been solved, the problem that can't accomplish the automatic synchronization online interaction of information, shift has been solved, sample preparation index is uncontrollable in the experimentation, problem not up to standard has been solved.

The foregoing description is intended to be illustrative rather than limiting, and it will be appreciated by those skilled in the art that many modifications, variations or equivalents may be made without departing from the spirit and scope of the invention as defined in the appended claims.

Claims

1. The utility model provides a multi-functional automatic post processing apparatus based on organism liquid sample filters which characterized in that: a storage component (300) is arranged in the sliding component (100), the sliding component (100) is also connected with the functional component (200) in a sliding manner, and the relative position of the functional component (200) and the storage component (300) is adjusted through sliding;

the sliding assembly (100) comprises a screw rod motor (105), a linear guide rail sliding block component (107) and a sliding platform (108), the linear guide rail sliding block component (107) is connected with the sliding platform (108) in a sliding mode, the sliding platform (108) is further in transmission connection with the screw rod motor (105), and the screw rod motor (105) is used for enabling the sliding platform (108) to move horizontally;

the functional component (200) comprises a container bottom plate (201), a guide rod air cylinder (205) and an ink-jet printer nozzle (207), the container bottom plate (201) is fixedly connected to the sliding platform (108), the guide rod air cylinder (205) is fixed to the container bottom plate (201) through an air cylinder mounting plate (204), the guide rod air cylinder (205) is used for axial telescopic movement of a vacuum sucker (202) and a pressing column (203), the ink-jet printer nozzle (207) is fixed to the container bottom plate (201) through a nozzle fixing seat (206), and the ink-jet printer nozzle (207) is used for information jet printing through horizontal movement;

the storage assembly (300) comprises a feeding cylinder (302) and a membrane collecting tank (308), the feeding cylinder (302) is in contact connection with code spraying packing paper (305) through a sliding block (304) for supporting the code spraying packing paper (305) in a floating mode, and a piston (309) supplies a filter screen support to slide downwards in a stepping mode in the membrane collecting tank (308).

2. The multifunctional automatic post-processing device based on biological fluid sample filtration as claimed in claim 1, wherein: the sliding assembly (100) further comprises a bottom plate (101), vertical plates (104) and a top plate (106), the bottom plate (101) is fixedly connected with the top plate (106) through the pair of vertical plates (104), the vertical plates (104) are provided with the lead screw motors (105), the top plate (106) is provided with the linear guide rail sliding block component (107), and the top plate (106) is provided with the image recognition camera (2).

3. The multifunctional automatic post-processing device based on biological fluid sample filtration as claimed in claim 2, characterized in that: the bottom plate (101) can be fixed or detached through rotation of the pair of butterfly bolts (102), fulcrum step screws (103) are respectively arranged on two sides of the bottom plate (101), the fulcrum step screws (103) on one side are rotation rotating shafts, and the fulcrum step screws (103) on the other side are positioned for rotation angles.

4. The multifunctional automatic post-processing device based on biological fluid sample filtration as claimed in claim 1, wherein: the guide rod air cylinder (205) with compression leg (203) transmission is connected, the inside vacuum chuck (202) that sets up in bottom of compression leg (203), vacuum chuck (202) with compression leg (203) terminal surface flushes, vacuum chuck (202) and vacuum pump intercommunication.

5. The multifunctional automatic post-processing device based on biological fluid sample filtration as claimed in claim 1, wherein: the storage assembly (300) further comprises a double-cavity base (301), the double-cavity base (301) is fixedly supported through a side support plate (303), and a small cavity (311) and a large cavity (312) are arranged in the double-cavity base (301) in a separated mode;

the feeding cylinder (302) is arranged below the small cavity (311), the code-spraying packing paper (305) is arranged in the small cavity (311), the top end of the code-spraying packing paper (305) is provided with a pluggable baffle (306), the top end of the baffle (306) is in contact with a fixed baffle (307), and the fixed baffle (307) is fixed on the top end surface of the double-cavity base (301);

the large cavity (312) is internally provided with the membrane collecting tank (308), and the inner wall of the membrane collecting tank (308) is in contact connection with the piston (309) through an O-shaped ring (310).