CN217359605U - Optical system of blood analyzer and blood analyzer - Google Patents
Optical system of blood analyzer and blood analyzer Download PDFInfo
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- CN217359605U CN217359605U CN202123178025.5U CN202123178025U CN217359605U CN 217359605 U CN217359605 U CN 217359605U CN 202123178025 U CN202123178025 U CN 202123178025U CN 217359605 U CN217359605 U CN 217359605U
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Abstract
The utility model discloses an optical system and blood analyzer of blood analyzer, optical system includes light source mechanism, collimating mechanism, plastic mechanism and photoelectric detection mechanism, collimating mechanism is used for carrying out the collimation to the detection light of light source mechanism transmission, plastic mechanism is used for carrying out the plastic to the detection light after collimating mechanism's collimation in order to form plastic light, plastic light is used for shining to flowing the room, photoelectric detection mechanism is used for receiving plastic light and flows the scattered light that indoor blood sample scattering formed through flowing, in order to obtain the measuring value of blood sample, wherein, plastic mechanism includes the first lens and the first pair of cemented lens that set gradually, this application can directly carry out the plastic to two at least directions through setting up first pair cemented lens, need not to carry out accurate adjustment again to two lenses in order to realize detecting the plastic of light in two directions, and then can simplify the assembly process of plastic mechanism, the precision requirement and the cost are reduced, and the accuracy of the subsequent detection result is improved.
Description
Technical Field
The utility model relates to the technical field of medical equipment, in particular to blood analyzer's optical system and blood analyzer.
Background
In a blood analyzer, a blood sample is generally obtained by optically detecting blood loaded in a flow cell by providing an optical system. The optical system generally comprises a light source mechanism, a collimating mechanism, a shaping mechanism and a photoelectric detection mechanism, wherein the light source mechanism is used for emitting detection light, the collimating mechanism is used for collimating the detection light, the shaping mechanism is used for shaping the collimated detection light, and the photoelectric detection mechanism is used for acquiring scattered light formed by scattering of the detection light by a blood sample in the flow chamber so as to detect the detection light.
At present, a shaping mechanism generally comprises a fast-axis focusing lens and a slow-axis focusing lens, and is used for shaping straight light from two directions respectively, the adjustment process of the shaping direction is complex, the precision requirement is high, and the subsequent detection result is greatly influenced.
SUMMERY OF THE UTILITY MODEL
The utility model provides an optical system and blood analyzer of blood analyzer to the plastic direction adjustment of plastic mechanism is complicated among the optical system of blood analyzer among the solution prior art, technical problem that the required precision is high.
In order to solve the above technical problem, the utility model discloses a technical scheme provide a blood analyzer's optical system, include:
a light source mechanism for emitting detection light;
a collimating mechanism for collimating the detection light;
a shaping mechanism for shaping the detection light collimated by the collimating mechanism to form shaped light, the shaped light being used for irradiating to a flow chamber;
and
the photoelectric detection mechanism is used for receiving scattered light formed by scattering of the shaping light by the blood sample in the flow chamber so as to obtain a detection value of the blood sample;
wherein the shaping mechanism comprises a first lens and a first cemented doublet.
In a specific embodiment, the first lens is configured to diverge the detection light collimated by the collimating mechanism along a first direction, and the first cemented doublet is configured to converge the detection light diverged by the first lens along the first direction and a second direction, where the first direction is perpendicular to the second direction.
In an embodiment, the first lens is a plano-concave cylindrical mirror or a plano-convex cylindrical mirror.
In a specific embodiment, the collimating mechanism includes an aspheric lens, a plane of the aspheric lens faces the light source mechanism, and a curved surface of the aspheric lens faces the shaping mechanism.
In a specific embodiment, the optical system further includes a collecting mechanism configured to collect forward scattered light formed by forward scattering of the shaping light by the blood sample in the flow chamber, and the photoelectric detection mechanism includes a forward scattered light detection unit configured to receive the forward scattered light collected by the collecting mechanism to obtain a first one of the detection values.
In a specific embodiment, the collecting mechanism includes a second lens and a third lens, and the forward scattered light is sequentially transmitted through the second lens and the third lens.
In a specific embodiment, the second lens is a second biconvex lens, the second biconvex lens is formed by coaxially gluing a first concave-convex lens and a first biconvex lens which are sequentially arranged, and the forward scattered light sequentially passes through the first concave-convex lens, the first biconvex lens and the third lens.
In a specific embodiment, the third lens is a third double cemented lens, the third double cemented lens is formed by a second biconvex lens and a second concave-convex lens coaxially arranged in sequence and cemented together, and the forward scattered light sequentially passes through the second lens, the second biconvex lens and the second concave-convex lens.
In a specific embodiment, the photodetection mechanism further comprises a side scattered light detection unit for receiving side scattered light formed by side scattering of the reshaped light by the blood sample in the flow chamber to acquire a second one of the detection values of the blood sample.
In order to solve the above technical problem, the present invention provides a blood analyzer according to another technical solution, which comprises a sample processing device and the above optical system, wherein the sample processing device is used for processing the blood sample and sending the processed blood sample to the flow chamber.
The utility model discloses blood analyzer's optical system includes light source mechanism, collimating mechanism, plastic mechanism and photoelectric detection mechanism, light source mechanism is used for the transmission to detect the light, collimating mechanism is used for carrying out the collimation to detecting the light, plastic mechanism is used for carrying out the plastic to the detection light after collimating mechanism's collimation so as to form the plastic light, the plastic light is used for shining to the room that flows, photoelectric detection mechanism is used for receiving the scattered light that the plastic light formed through the blood sample scattering in the room that flows, in order to obtain the detected value of blood sample, wherein, plastic mechanism includes the first lens and the first pair of cemented lens that set gradually, compare current two directions that detect the light respectively to carry out the plastic through two lens respectively, this application can directly carry out the plastic to two at least directions through setting up first pair cemented lens, need not to carry out accurate adjustment again to two lenses in order to realize detecting the shaping in two directions of light, and then can simplify the assembly process of plastic mechanism, reduce its precision requirement and cost, be favorable to improving subsequent measuring result's accuracy.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained without inventive work, wherein:
fig. 1 is a schematic diagram of an external three-dimensional structure of an embodiment of an optical system of a blood analyzer according to the present invention;
FIG. 2 is a schematic diagram of the internal three-dimensional structure of an embodiment of the optical system of the blood analyzer of the present invention;
fig. 3 is a schematic diagram of an internal top view of an embodiment of the optical system of the blood analyzer of the present invention;
FIG. 4 is a schematic diagram of an optical path in an embodiment of an optical system of the blood analyzer
Fig. 5 is a schematic diagram of an internal cross-sectional structure of an optical system of the blood analyzer according to the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work all belong to the protection scope of the present invention.
The terms "first", "second" and "first" in this application are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or to implicitly indicate the number of technical features indicated. In the description of the present application, "plurality" means at least two, e.g., two, three, etc., unless explicitly specifically limited otherwise. Furthermore, the terms "include" and "have," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus. And the term "and/or" is only one kind of association relationship describing the associated object, and means that there may be three kinds of relationships, for example, a and/or B, and may mean: a exists alone, A and B exist simultaneously, and B exists alone. In addition, the character "/" herein generally indicates that the former and latter related objects are in an "or" relationship.
Referring to fig. 1 to 4, an embodiment of an optical system 10 of a blood analyzer of the present invention includes a light source mechanism 100, a collimating mechanism 200, a shaping mechanism 300 and a photoelectric detection mechanism, the light source mechanism 100 is configured to emit detection light, the collimating mechanism 200 is configured to receive the detection light and collimate the detection light, the first shaping mechanism 300 is configured to receive the collimated detection light and shape the detection light collimated by the collimating mechanism 200 to form shaped light, the shaped light is configured to irradiate to a flow chamber 400, the photoelectric detection mechanism is configured to receive scattered light formed by scattering of a blood sample in the flow chamber 400 through the shaped light, so as to obtain a detection value of the blood sample in the flow chamber 400, wherein the shaping mechanism 300 includes a first lens 310 and a first doublet-cemented lens 320 which are sequentially disposed, the collimated detection light sequentially passes through the first lens 310 and the first doublet-cemented lens 320, directly carry out the plastic to two at least directions through setting up first doublet 320, need not to carry out the ascending plastic in two directions of accurate adjustment in order to realize detecting the light to two lenses again, and then can simplify the assembly process of plastic mechanism 300, reduce its required precision and cost, be favorable to improving subsequent testing result's accuracy.
In this embodiment, the photoelectric detection mechanism can detect the size of blood cells in the blood sample.
In this embodiment, the first lens 310 is configured to diverge the detection light collimated by the collimating mechanism 200 along a first direction, and the first cemented doublet 320 is configured to converge the detection light diverged by the first lens 310 along a first direction and a second direction, where the first direction is perpendicular to the second direction, and the first direction and the second direction may be a fast axis direction and a slow axis direction of the detection light, respectively, so as to shape the detection light in two directions, and facilitate subsequent detection.
In this embodiment, the first lens 310 may be a plano-concave cylindrical lens, the concave surface of the first lens 310 faces the collimating mechanism 200, and the plane of the first lens 310 faces the first cemented doublet 320, so that the detection light enters from the concave surface of the first lens 310 and exits from the plane surface of the first lens 310, thereby achieving the effect of diverging the detection light in the first direction.
In other embodiments, the first lens 310 may also be a plano-convex cylindrical lens, the convex surface of the first lens 310 faces the collimating mechanism 200, and the plane of the first lens 310 faces the first cemented doublet 320, so that the detection light enters from the convex surface of the first lens 310 and exits from the plane of the first lens 310, so as to achieve the effect of converging the detection light in the second direction.
In this embodiment, the collimating mechanism 200 may include an aspheric lens, a plane of the aspheric lens faces the light source mechanism 100, and a curved surface of the aspheric lens faces the shaping mechanism 300, so that the detection light enters from the plane of the aspheric lens and exits from the curved surface of the aspheric lens, thereby achieving a collimating effect on the detection light, and facilitating subsequent shaping and detection of light.
In this embodiment, the optical system 10 may further include a collecting mechanism 600, the collecting mechanism 600 is configured to collect forward scattered light formed by forward scattering of the shaping light by the blood sample in the flow chamber 400, the photodetection mechanism includes a forward scattered light detection unit 500, the forward scattered light detection unit 500 is configured to receive the forward scattered light collected by the collecting mechanism 600, so as to obtain a first detection value of the detection values of the blood sample, the collecting mechanism 600 is disposed between the flow chamber 400 and the forward scattered light detection unit 500, and is configured to collect the forward scattered light, so that a light collecting effect can be further improved, and accuracy of a detection result is improved.
In this embodiment, the collecting mechanism 600 may include a second lens 610 and a third lens 620, and the forward scattered light is sequentially transmitted through the second lens 610 and the third lens 620 to achieve collection of the forward scattered light.
In this embodiment, the second lens 610 may be a second biconvex lens formed by a first concave-convex lens 611 and a first biconvex lens 612 coaxially disposed in sequence, the forward scattered light sequentially passes through the first concave-convex lens 611, the first biconvex lens 612 and the third lens 620, a convex surface of the first concave-convex lens 611 faces the flow chamber 400, a concave surface of the first concave-convex lens 611 is cemented with one convex surface of the first biconvex lens 612, and the other convex surface of the first biconvex lens 612 faces the photodetection mechanism, so that the forward scattered light enters from the convex surface of the first concave-convex lens 611 and exits from the other convex surface of the first biconvex lens 612, thereby achieving a converging effect on the forward scattered light and facilitating subsequent detection of light.
In this embodiment, the third lens 620 may be a third double cemented lens, the third double cemented lens is formed by a second biconvex lens 621 and a second meniscus lens 622 coaxially disposed in sequence, the forward scattered light sequentially passes through the second lens 610, the second biconvex lens 621 and the second meniscus lens 622, one convex surface of the second biconvex lens 621 faces the flow chamber 400, the other convex surface of the second biconvex lens 621 is cemented with the concave surface of the second meniscus lens 622, and the convex surface of the second meniscus lens 622 faces the photoelectric detection mechanism, so that the forward scattered light enters from one convex surface of the second biconvex lens 621 and exits from the convex surface of the second meniscus lens 622, so as to realize a converging effect on the forward scattered light, and facilitate subsequent detection on light.
In this embodiment, the photodetection mechanism may further include a side scattered light detection unit 721, the side scattered light detection unit 721 may be disposed in a side direction of the flow chamber 400, and the side scattered light detection unit 721 may be configured to receive side scattered light formed by side scattering of the reshaped light by the blood sample in the flow chamber 400 to obtain a second detection value among the detection values of the blood sample, thereby enabling detection of the internal complexity of blood cells of the blood sample, the number of blood cells, the density of cytoplasm and cell membrane of the blood cells, the content of cellular nucleic acid, and the like.
In this embodiment, the optical system 10 may further include a housing 800, and the light source mechanism 100, the collimating mechanism 200, the shaping mechanism 300, the flow chamber 400, the photodetecting mechanism, and the like may be disposed in the housing 800, and the housing 800 may have a protection and dust-proof effect.
Referring to fig. 1 to 5, another embodiment of the optical system 10 of the blood analyzer of the present invention includes a light source mechanism 100, a front light mechanism, a lateral light collecting mechanism 710 and a lateral light detecting unit 720, wherein the light source mechanism 100 is configured to emit detection light, the front light mechanism is configured to receive the detection light and collimate and/or shape the detection light to irradiate the flow chamber 400, the lateral light collecting mechanism 710 is disposed laterally to the flow chamber 400 and is configured to collect lateral light formed by the detection light irradiating a blood sample in the flow chamber 400, the lateral light detecting unit 720 is configured to receive the lateral light collected by the lateral light collecting mechanism 710 to obtain a detection value of the blood sample, the lateral light collecting mechanism 710 includes a first collimating unit 711 and a converging unit 712 sequentially disposed, the first collimating unit 711 is configured to collimate the lateral light, the converging unit 712 is configured to converge the lateral light collimated by the first collimating unit 711, the problem that lateral light energy is low and detection is not easy can be solved, the precision requirement on the lateral light detection unit 720 is reduced, and the accuracy and the reliability of a detection result are improved.
In this embodiment, the first collimating unit 711 may include an aspheric lens, a plane of the aspheric lens faces the flow chamber 400, and a curved surface of the aspheric lens faces the converging unit 712, so that the lateral light enters from the plane of the aspheric lens and exits from the curved surface of the aspheric lens, so as to achieve a collimating effect on the lateral light, and facilitate subsequent convergence, collection and detection of light rays.
In this embodiment, the converging unit 712 may include a plano-convex lens, a convex surface of the plano-convex lens faces the first collimating unit 711, and a plane of the plano-convex lens faces away from the first collimating unit 711, so that lateral light enters from the convex surface of the plano-convex lens and exits from the plane of the plano-convex lens, thereby achieving a converging effect on the lateral light, and facilitating subsequent collection and detection of light.
In other embodiments, the converging unit may also be a biconvex lens or a biconic lens, which is not limited herein.
In the present embodiment, the lateral light detection unit 720 can detect the internal complexity of blood cells in the blood sample, the number of blood cells, the cytoplasm of blood cells, the density of cell membranes, and the like.
In this embodiment, the optical system may further include a light splitting mechanism 730 and a filter mechanism 740, the light splitting mechanism 730 is configured to receive the side light collected by the side light collecting mechanism 710 and split the side light into side scattered light and side fluorescent light, the side light detecting unit 720 includes a side scattered light detecting unit 721 and a side fluorescent light detecting unit 722, the filter mechanism 740 is disposed between the light splitting mechanism 730 and the side fluorescent light detecting unit 722, the filter mechanism 740 is configured to filter the side scattered light, the side scattered light detecting unit 721 is configured to receive the side scattered light to obtain a first detection value among detection values of the blood sample, so as to detect an internal complexity of blood cells of the blood sample, a number of blood cells, cytoplasm of the blood cells, a density of cell membranes, and the like according to the first detection value, the side fluorescent light detecting unit 722 is configured to receive the side fluorescent light so as to obtain a second detection value among the detection values of the blood sample, so as to detect the content of cellular nucleic acid and the like of the blood sample based on the second detection value.
In the present embodiment, the light splitting mechanism 730 may include a dichroic mirror.
In this embodiment, the front light mechanism may include a second collimating unit 200 and a shaping unit 300, the shaping unit 300 includes a first lens 310 and a first cemented doublet 320, and the detection light sequentially passes through the second collimating unit 200, the first lens 310 and the first cemented doublet 320, wherein the structures of the second collimating unit 200 and the shaping unit 300 are as described in the above embodiment of the optical system 10 of the blood analyzer, and are not described herein again.
In this embodiment, the optical system 10 may further include a forward scattered light collecting mechanism 600 and a forward scattered light detecting unit 500, wherein the structures of the forward scattered light collecting mechanism 600 and the forward scattered light detecting unit 500 are referred to the above-mentioned embodiment of the optical system 10, and are not described herein again.
In this embodiment, the optical system 10 may further include a housing 800, and the light source mechanism 100, the front light mechanism, the flow cell 400, the lateral light collecting mechanism 710, the lateral light detecting unit 720, and the like may be disposed in the housing 800, and the housing 800 may have protection and dust prevention effects.
The embodiment of the blood analyzer of the present invention includes a sample processing device (not shown in the figure) and an optical system 10, wherein the sample processing device is used for processing the blood sample and sending the processed blood sample to the flow chamber 400 of the optical system 10, and the structure of the optical system 10 is referred to the embodiment of the optical system 10 of the blood analyzer, which is not described herein again.
The above only is the embodiment of the present invention, not limiting the patent scope of the present invention, all the equivalent structures or equivalent processes that are used in the specification and the attached drawings or directly or indirectly applied to other related technical fields are included in the patent protection scope of the present invention.
Claims (10)
1. An optical system of a blood analyzer, comprising:
a light source mechanism for emitting detection light;
a collimating mechanism for collimating the detection light;
a shaping mechanism for shaping the detection light collimated by the collimating mechanism to form shaped light, the shaped light being used for irradiating to a flow chamber; and
the photoelectric detection mechanism is used for receiving scattered light formed by scattering the shaped light by a blood sample in the flow chamber so as to acquire a detection value of the blood sample;
the shaping mechanism comprises a first lens and a first cemented doublet which are arranged in sequence.
2. The optical system of claim 1, wherein the first lens is configured to diverge the detection light collimated by the collimating mechanism in a first direction, and the first cemented doublet is configured to converge the detection light diverged by the first lens in the first direction and a second direction, and the first direction is perpendicular to the second direction.
3. The optical system according to claim 1, wherein the first lens is a plano-concave cylindrical mirror or a plano-convex cylindrical mirror.
4. The optical system of claim 1, wherein the collimating mechanism comprises an aspheric lens having a planar surface facing the light source mechanism and a curved surface facing the shaping mechanism.
5. The optical system of claim 1, further comprising a collecting mechanism for collecting forward scattered light formed by forward scattering of the shaped light by the blood sample in the flow chamber, wherein the photodetecting mechanism comprises a forward scattered light detection unit for receiving the forward scattered light collected by the collecting mechanism to obtain a first one of the detection values of the blood sample.
6. The optical system of claim 5, wherein the collection mechanism comprises a second lens and a third lens, the forward scattered light being transmitted through the second and third lenses in sequence.
7. The optical system of claim 6, wherein the second lens is a second biconvex lens formed by a first concave-convex lens and a first biconvex lens coaxially arranged in sequence, and the forward scattered light passes through the first concave-convex lens, the first biconvex lens and the third lens in sequence.
8. The optical system of claim 6, wherein the third lens is a third double cemented lens formed by a second biconvex lens and a second meniscus lens coaxially arranged in sequence, and the forward scattered light passes through the second lens, the second biconvex lens and the second meniscus lens in sequence.
9. The optical system of claim 1, wherein the photodetection mechanism further comprises a side scatter detection unit for receiving side scatter light formed by side scatter of the reshaped light by the blood sample within the flow chamber to obtain a second one of the detection values of the blood sample.
10. A blood analyzer comprising a sample processing device for processing the blood sample and delivering the processed blood sample to the flow cell, and the optical system of any one of claims 1 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123178025.5U CN217359605U (en) | 2021-12-16 | 2021-12-16 | Optical system of blood analyzer and blood analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123178025.5U CN217359605U (en) | 2021-12-16 | 2021-12-16 | Optical system of blood analyzer and blood analyzer |
Publications (1)
| Publication Number | Publication Date |
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| CN217359605U true CN217359605U (en) | 2022-09-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202123178025.5U Active CN217359605U (en) | 2021-12-16 | 2021-12-16 | Optical system of blood analyzer and blood analyzer |
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| CN (1) | CN217359605U (en) |
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2021
- 2021-12-16 CN CN202123178025.5U patent/CN217359605U/en active Active
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