CN217359207U - Liquid-based sample treatment equipment - Google Patents

Abstract

The utility model relates to a liquid-based film-making technical field specifically discloses a liquid-based sample treatment facility. The liquid-based sample processing equipment comprises a shell, a bearing platform, a soaking mechanism, a transmission system and a control system; the shell is provided with a containing cavity and a transmission port, and the transmission port is used for being communicated with a DNA ploid analysis device; the bearing platform, the soaking mechanism and the transmission system are contained in the containing cavity; the control system controls the transmission system to transfer the sample in the containing cavity to soak the sample, and transfers the soaked sample to the transfer port. The liquid-based sample processing device has a shorter sample processing stroke and higher sample processing efficiency, and has a smaller size.

Description

Liquid-based sample treatment equipment

Technical Field

The utility model discloses liquid relates to base system piece technical field, especially relates to a lotion base sample treatment facility.

Background

Common liquid-based sample processing equipment generally operates according to the sequence of elution, uniform mixing, centrifugal separation, sedimentation, dyeing and mounting, but on one hand, the operation flow cannot fully utilize all functional parts of the liquid-based integrated machine, so that the vacancy rate of all functional parts is high, and the sheet making efficiency is low; on the other hand, the liquid-based all-in-one machine is large in size, and the assembly of each part is loose, so that the whole treatment stroke is long.

SUMMERY OF THE UTILITY MODEL

The embodiment of the utility model provides a purpose provides a liquid base sample treatment facility aims at solving current liquid base sample treatment facility at least and has that each part vacancy rate is higher, film-making efficiency is lower and the longer scheduling problem of film-making stroke.

In order to achieve the above object, the embodiment of the present invention adopts the following technical solutions:

a liquid-based sample processing device comprises a shell, a bearing platform, a soaking mechanism, a transmission system and a control system;

the shell is provided with a containing cavity and a conveying port, and the conveying port is used for being communicated with a DNA ploid analysis device;

the bearing platform, the soaking mechanism and the transmission system are contained in the containing cavity;

the control system controls the transmission system to transfer the sample in the containing cavity so as to soak the sample, and transfers the soaked sample to the conveying port.

In a possible implementation manner, the bearing platform is provided with a buffer position, the soaking mechanism is arranged on the buffer position, and the soaking mechanism is used for containing an ethanol solution.

In a possible embodiment, the transfer system includes a transfer channel disposed in the accommodating cavity and communicating with the transfer port to transfer the sample to the transfer port.

In a possible embodiment, the housing includes a front side plate, a rear side plate, a left side plate, a right side plate and a top plate, and the front side plate, the rear side plate, the left side plate, the right side plate and the top plate enclose to form the accommodating cavity;

the conveying opening is formed in the left side plate or the right side plate.

In a possible implementation manner, the conveying channel is arranged at the top of the bearing platform close to the rear side plate, and the conveying channel extends along the direction from the left side plate to the right side plate;

and/or, the transmission channel is movably provided with a storage mechanism, the storage mechanism is provided with at least one storage groove, and ethanol solution is contained in the storage groove and is used for containing the soaked samples and transferring the samples to the conveying port through the transmission channel.

In a possible implementation manner, the bearing platform divides the accommodating cavity into an upper cavity and a lower cavity, and a surface of the bearing platform facing the upper cavity is provided with a settling position and a buffering position.

In one possible embodiment, the liquid-based sample processing device comprises an elution and blending mechanism and a centrifugation mechanism, wherein the elution and blending mechanism and the soaking mechanism are arranged in the upper chamber; the centrifugal mechanism is arranged in the lower chamber.

In one possible embodiment, the transport system comprises a transfer mechanism and a lifting mechanism;

the transfer mechanism is used for transferring the sample to an elution and blending mechanism for elution and blending treatment and transferring the sample subjected to the elution and blending treatment to a centrifuge tube;

the lifting mechanism is used for transferring the centrifuge tube to the centrifugation mechanism for centrifugation and transferring the centrifuged sample to a sedimentation position for sedimentation.

In a possible embodiment, the transfer system further comprises a first gripper and a second gripper, wherein the first gripper is used for transferring the sample subjected to sedimentation treatment to the soaking mechanism containing ethanol solution for soaking treatment; the second gripper is used for transferring the soaked sample.

In a possible embodiment, the housing includes a front side plate, a rear side plate, a left side plate, a right side plate and a top plate, and the front side plate, the rear side plate, the left side plate, the right side plate and the top plate enclose the accommodating cavity;

the liquid-based sample processing equipment further comprises a first drawer, a second drawer and a third drawer, wherein the first drawer, the second drawer and the third drawer are arranged side by side at intervals and are movably mounted on the bearing platform along the direction from the front side plate to the rear side plate respectively;

the first drawer is used for loading a centrifuge tube, a pipetting tip and a sample container so as to deliver the centrifuge tube, the pipetting tip and the sample container filled with a sample into the containing cavity;

the second drawer is used for loading a sedimentation assembly to deliver the sedimentation assembly into the containing cavity;

the third drawer is used for loading a carrier to deliver the carrier into the containing cavity.

Compared with the prior art, the utility model provides a liquid base sample treatment facility, which comprises a housin, load-bearing platform, soak the mechanism, transmission system and control system all accept in the casing, the casing is equipped with the transfer port of being connected with DNA ploidy analytical equipment, on the one hand, can effectually shorten the stroke of sample treatment, on the other hand, soak the back and convey to the transfer port in order to DNA ploidy analytical equipment transmission through transmission system immediately, can effectively improve the treatment effeciency of liquid base sample treatment facility, when reducing other functional component of liquid base sample treatment facility, can reduce the horizontal volume of liquid base sample treatment facility effectively, make liquid base sample treatment facility miniaturized.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

Fig. 1 is a schematic top view of a liquid-based sample processing apparatus according to an embodiment of the present invention;

fig. 2 is a schematic top view of the liquid-based sample processing apparatus according to an embodiment of the present invention after the top plate and a part of the transmission system are removed;

FIG. 3 is an enlarged view of a portion of FIG. 2 at A;

FIG. 4 is an enlarged view of a portion of FIG. 2 at B;

fig. 5 is a schematic perspective view of a liquid-based sample processing apparatus according to an embodiment of the present invention after a part of a housing and a part of a transmission system are removed;

fig. 6 is a schematic perspective view of a liquid-based sample processing apparatus according to a first embodiment of the present invention;

FIG. 7 is an enlarged partial schematic view at C of FIG. 6;

fig. 8 is a schematic perspective view of another view angle of a liquid-based sample processing apparatus according to an embodiment of the present invention;

FIG. 9 is an enlarged partial schematic view of FIG. 8 at D;

fig. 10 is a simplified schematic diagram of a control relationship of a liquid-based sample processing apparatus according to an embodiment of the present invention;

fig. 11 is an exploded view of a settling assembly according to an embodiment of the present invention;

fig. 12 is a schematic top view of a liquid-based sample processing apparatus according to an embodiment of the present invention.

Reference numerals:

10. a liquid-based sample processing device;

11. a housing; 110. an accommodating chamber; 1101. a transfer port; 1102. an exhaust hole; 111. a front side plate; 112. a rear side plate; 113. a left side plate; 114. a right side plate; 115. a top plate;

12. a load-bearing platform; 121. a cache bit; 122. settling; 123. a recovery port; 124. avoiding the through hole;

13. a soaking mechanism; 130. a soaking tank;

14. a transmission system; 141. a first manipulator; 142. a second manipulator; 143. a sample adding mechanism; 144. a lifting mechanism; 145. a first gripper; 146. a second gripper; 147. a transmission channel; 148. a third manipulator;

15. a control system; 16. a storage mechanism; 17. an elution and uniform mixing mechanism; 18. a centrifugal mechanism; 19. a tilting mechanism; 20. a first drawer; 21. a second drawer; 22. a third drawer; 23. a code scanning mechanism; 24. a code printing mechanism; 25. a pipe disassembling mechanism; 26. a support; 27. a disassembly mechanism; 28. a liquid adding mechanism; 30. a sedimentation component; 31. a base; 32. a glass slide; 33. a settling tube; 40. a carrier; 50. DNA ploidy analysis equipment.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all, of the embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts all belong to the protection scope of the present invention.

Example one

Fig. 1 to 10 are schematic structural diagrams of a liquid-based sample processing apparatus 10 according to a first embodiment of the present invention.

Referring to fig. 1, fig. 3, fig. 4, fig. 5, fig. 6, and fig. 10, a liquid-based sample processing apparatus 10 of the present embodiment includes a housing 11, a carrying platform 12, a soaking mechanism 13, a transmission system 14, and a control system 15. Wherein the housing 11 has a containing cavity 110, and the housing 11 is provided with a transfer port 1101, the transfer port 1101 is used for communicating the liquid-based sample processing device 10 with the DNA ploidy analysis device 50 to realize the transfer of the sample processed by the liquid-based sample processing device 10 to the DNA body analysis device; the bearing platform 12, the soaking mechanism 13 and the transmission system 14 are all accommodated in the accommodating cavity 110; the control system 15 controls the transport system 14 to transfer the sample placed in the containing chamber 110 to perform the soaking process on the sample, and controls the transport system 14 to transfer the soaked sample to the transfer port 1101.

Referring to fig. 1, 6 and 8, in some embodiments, the housing 11 includes a front plate 111, a rear plate 112, a left plate 113, a right plate 114 and a top plate 115, the front plate 111, the rear plate 112, the left plate 113, the right plate 114 and the top plate 115 enclose the accommodating cavity 110, and the delivery port 1101 is disposed on the left plate 113. In some embodiments, the housing 11 is further provided with a vent 1102 to vent toxic and harmful gases such as solvent volatilized within the liquid-based sample processing device 10. In some embodiments, vents 1102 are provided in the top plate 115, and the vents 1102 communicate with a gas recovery device to prevent toxic and harmful gases from diffusing into the air and contaminating the user.

Referring to fig. 3, 5, and 6, in some embodiments, the supporting platform 12 divides the accommodating chamber 110 into an upper chamber (not shown) and a lower chamber (not shown), a surface of the supporting platform 12 facing the upper chamber is provided with a settling position 122 and a buffer position 121, the settling position 122 is used for placing the settling component 30 during settling, and the buffer position 121 is used for placing the soaking mechanism 13. By adopting the structural design, the transverse size of the liquid-based sample processing device 10 can be effectively reduced, so that the liquid-based sample processing devices 10 are distributed along the vertical direction, the structural compactness of the liquid-based sample processing device 10 is favorably improved, and the liquid-based sample processing device 10 is miniaturized. It should be noted that, in the utility model discloses in, bearing platform 12's top, both can refer to the region of enclosing of cushion cap platform upper surface, also can be that orthographic projection falls on the top space region of bearing platform 12 upper surface, therefore it sets up at bearing platform 12's top to say that certain part, can be that certain part has physical contact with bearing platform 12, also can not have physical contact, no matter have or not physical contact, all belong to the utility model discloses the scheme of protection.

Referring to fig. 4, in some embodiments, the liquid-based sample processing apparatus 10 further includes an elution and blending mechanism 17 and a centrifugation mechanism 18, the elution and blending mechanism 17 is disposed in the upper chamber, and the elution and blending mechanism 17 is configured to elute and blend the sample sent into the liquid-based sample processing apparatus 10 to obtain a uniform sample; and centrifugal mechanism 18 locates down the cavity to be used for carrying out centrifugal treatment to the sample that obtains through elution mixing processing, locate cavity down with centrifugal mechanism 18, except can effectively shortening the horizontal size of liquid-based sample treatment facility 10, can also effectively avoid centrifugal mechanism 18 to produce the interference to other mechanisms when carrying out centrifugal treatment to the sample, improved the reliability of liquid-based sample treatment facility 10. In some embodiments, the platform 12 defines an escape opening 124 for delivering centrifuge tubes in the upper chamber to the centrifuge mechanism 18 or removing and transferring centrifuge tubes from the centrifuge mechanism 18 to the upper chamber. In some embodiments, the escape through-hole 124 is used for the lifting mechanism 144 to descend from the upper chamber to the lower chamber or ascend from the lower chamber to the upper chamber, thereby fully utilizing the space of the liquid-based sample processing device 10 in the vertical direction without increasing the lateral dimension of the liquid-based sample processing device 10.

Referring to fig. 2, 3, and 10, in some embodiments, the liquid-based sample processing apparatus 10 further includes an inclining mechanism 19, the inclining mechanism 19 is disposed at the top of the supporting platform 12, the inclining mechanism 19 is provided with a centrifuge tube mounting position (not shown in the drawings) for placing a centrifuge tube, and the centrifuge tube is driven to incline by a certain angle under the control of the control system 15, so as to conveniently add the gradient separation liquid into the centrifuge tube and elute and mix the sample obtained. In some embodiments, the tilting mechanism 19 drives the centrifuging tube and takes place the slope back, and the center pin of centrifuging tube is 0 ~ 60 with the contained angle that vertical axle becomes, and such contained angle can guarantee the gradient separation effect on the one hand, and on the other hand can avoid the sample to flow out from the centrifuging tube.

Referring to fig. 9 and 8, in some embodiments, the liquid-based sample processing apparatus 10 further includes a liquid adding mechanism 28, and the liquid adding mechanism 28 is disposed on the top of the carrying platform 12 for adding the gradient separation liquid into the tilted centrifuge tube.

Referring to fig. 9, 8, 4, and 3, in some embodiments, the transport system 14 includes a first manipulator 141, wherein the first manipulator 141 is disposed on the top of the platform 12 for transferring the sample container containing the sample to the elution and blending mechanism 17. In some embodiments, the transport system 14 further comprises a second robot 142, the second robot 142 being disposed on top of the load-bearing platform 12 for transferring the centrifuge tubes to the tilt mechanism 19.

Referring to fig. 1, 3, 5 and 10, in some embodiments, the transmission system 14 includes a transmission channel 147, and the transmission channel 147 is disposed in the accommodating cavity 110 and is communicated with the transfer port 1101, so that the soaked sample can be transferred to the transfer port 1101 through the transmission channel 147, so as to automatically transport the sample to be analyzed to the DNA ploidy analysis apparatus 50. In some embodiments, the transfer channel 147 is disposed at the top of the load-bearing platform 12 near the rear side panel 112, and the transfer channel 147 extends in the direction from the left side panel 113 to the right side panel 114. In some embodiments, the transmission channel 147 is in physical contact with the load-bearing platform 12, and in some embodiments, the transmission channel 147 is not in physical contact with the load-bearing platform 12, i.e., is spaced apart from the load-bearing platform 12. In some embodiments, the transmission channel 147 is connected at one end to the left side plate 113 and at the other end to the right side plate 114. In some embodiments, the liquid-based sample processing apparatus 10 further includes a storage mechanism 16, and the storage mechanism 16 is movably mounted on the transmission channel 147, so that the soaked sample can be placed in the storage mechanism 16 and then transmitted by the transmission channel 147, and thus the soaked sample can be prevented from being polluted, and meanwhile, the residual soaking liquid of the sample can be prevented from dripping into the transmission channel 147 to pollute the transmission channel 147, and the like. In some embodiments, the storage mechanism 16 is provided with at least one accommodating groove (not labeled in the figures), and the accommodating groove is filled with an ethanol solution, so that adverse effects such as appearance deformation caused by drying of the sample in the transmission process can be effectively avoided. In some embodiments, the buffer bits 121 are disposed between the sinking bits 122 and the transmission channel 147, which is advantageous to shorten the sample transferring stroke, so as to make the structure of the liquid-based sample processing apparatus 10 more compact.

Referring to fig. 10, 7 and 3, in some embodiments, the transport system 14 further includes a first grip 145 and a second grip 146, wherein the first grip 145 is used for transferring the settled sample to the soaking mechanism 13 containing the ethanol solution for soaking; while the second hand grip 146 is used to perform the immersion processed sample. In some embodiments, the second grip 146 transfers the soaked sample to the storage mechanism 16 containing an ethanol solution. In some embodiments, the first hand grip 145 is disposed on top of the load-bearing platform 12 and adjacent to the buffer position 121, while the second hand grip 146 is disposed on the top plate 115 and is movable relative to the top plate 115.

Referring to fig. 5, 6, 7, 1 and 3, in some embodiments, the liquid-based sample processing apparatus 10 further includes a first drawer 20, a second drawer 21 and a third drawer 22, wherein the first drawer 20, the second drawer 21 and the third drawer 22 are accommodated in the upper chamber and movably mounted on the supporting platform 12 along a direction from the front plate 111 to the rear plate 112, and the second drawer 21 is disposed between the first drawer 20 and the third drawer 22 and has a space between two adjacent drawers. In some embodiments, first drawer 20 is used to load centrifuge tubes, pipette tips, and sample containers to deliver centrifuge tubes, pipette tips, and sample containers containing samples into receiving cavity 110; the second drawer 21 is used for loading the sedimentation assembly 30 to deliver the sedimentation assembly 30 into the receiving chamber 110, and when the sedimentation assembly 30 is added to the liquid-based sample processing apparatus 10, the sedimentation assembly 30 is loaded into the second drawer 21, and the second drawer 21 is pushed into position into the sedimentation position 122; when use is complete, the second drawer 21 is pulled out, and the settling assembly 30 can be removed. In some embodiments, the number of the second drawers 21 is two, two second drawers 21 are arranged side by side and spaced apart, one end of each of the two second drawers 21 faces the rear side wall, and the buffer position 121 is arranged between one of the second drawers 21 and the rear side wall. The third drawer 22 is used to load the carriers 40 to deliver the carriers 40 into the receiving cavities 110. In some embodiments, the carrier 40 is a slide basket that is placed in the soak tank 130 of the soak mechanism 13 by the second hand grip 146 after being delivered into the receiving chamber 110.

Referring to fig. 5 and 6, in some embodiments, the liquid-based sample processing device 10 further includes a bracket 26, the housing 11 is connected to the bracket 26 to form the accommodating cavity 110, the housing 11 and the carrying platform 12 are supported by the bracket 26, and the structural strength of the liquid-based sample processing device 10 can be effectively improved by providing the bracket 26.

Referring to fig. 4, 5, 3, 1 and 10, in some embodiments, the liquid-based sample processing apparatus 10 further includes a code scanning mechanism 23, the code scanning mechanism 23 is disposed on the top of the carrying platform 12, i.e., is installed in the upper chamber, the code scanning mechanism 23 is configured to scan the sample containers in the first drawer 20 to obtain corresponding information of the sample, and then transfer the sample containers to the elution and mixing mechanism 17; and is used for scanning the centrifugal tube to obtain the corresponding information of the centrifugal tube, and then transfers the centrifugal tube to the tilting mechanism 19. In some embodiments, the code scanning mechanism 23 is disposed proximate to the right side plate 114 to efficiently utilize the space of the liquid-based sample processing device 10, make the components of the liquid-based sample processing device 10 more compact, and at the same time, shorten the stroke of the transport system 14.

Referring to fig. 4, 2, and 9, in some embodiments, the platform 12 is provided with a recovery port 123, and the recovery port 123 is used for recovering the pipette tip. After the sample adding mechanism 143 transfers the sample in the elution and mixing mechanism 17 to the centrifuge tube using the liquid transfer tip, the liquid transfer tip is separated from the sample adding mechanism 143, so that the liquid transfer tip falls into the recovery port 123, and the recovery processing of the liquid transfer tip is realized. In some embodiments, the liquid-based sample processing apparatus 10 further comprises a detaching mechanism 27, the detaching mechanism 27 is disposed on the top of the supporting platform 12 and is close to the recovery port 123, and by disposing the detaching mechanism 27, the sample adding mechanism 143 can be effectively detached from the pipette tip, so that the pipette tip is separated from the sample adding mechanism 143.

Referring to fig. 11 and 3, in some embodiments, sedimentation assembly 30 includes a base 31, a sedimentation tube 33, a slide 32, and a seal (not shown); the slide glass 32 is placed on the base 31, one end of the sedimentation tube 33 is connected to the base 31, and the other end extends in the normal direction of the base 31, the slide glass 32 is disposed between the sedimentation tube 33 and the base 31, and the portion where the sedimentation tube 33 abuts against the slide glass 32 is sealed by a sealing material. When a sample is injected into the settling tube 33 from one port of the settling tube 33 far from the base 31, the sample falls along the radial direction of the settling tube 33 and falls on the surface of the slide glass 32, and the surface of the slide glass 32 is settled, so that the settling treatment is completed, and if the sample settled on the surface of the slide glass 32 does not need to be dyed, the slide glass 32 is separated from the settling tube 33 and the base 31 to obtain the slide glass 32, and then the slide glass 32 can be transferred to the soaking mechanism 13 for soaking treatment and the like; then, the slide glass 32 is detached from the sedimentation tube 33 and the base 31 to obtain the slide glass 32, and the specimen subjected to sedimentation is attached to the obtained slide glass 32 and transferred to the soaking mechanism 13 to be soaked and the like.

Referring to fig. 2, 3 and 11, in some embodiments, the liquid-based sample processing apparatus 10 further includes a tube detaching mechanism 25, and the tube detaching mechanism 25 is disposed on top of the supporting platform 12, i.e., in the upper chamber, for detaching the sedimentation processed sedimentation assembly 30, so as to separate the slide 32 from the base 31 and the sedimentation tube 33.

Referring to fig. 7, 10 and 3, in some embodiments, the transport system 14 further includes a third robot 148, the third robot 148 being disposed on top of the carrying platform 12 for grasping the sedimentation assembly 30 and transferring the sedimentation assembly 30 to the pipe dismantling mechanism 25 for the pipe dismantling process.

Referring to fig. 5, 11 and 4, in some embodiments, the liquid-based sample processing apparatus 10 further includes a coding mechanism 24, the coding mechanism 24 is disposed on the top of the platform 12, i.e., in the upper chamber, for coding the sedimentation assembly 30 before sedimentation, so that the slide 32 is encoded, thereby encoding the slide 32 with information obtained by scanning the sample containers and/or the centrifuge tubes with the coding mechanism 23. Due to the structural design, the slide glass 32 in the sedimentation assembly 30 can be subjected to coding treatment and reused, so that the sample is prevented from being disordered in the transferring process, and the informatization management of the sample is facilitated.

Referring to fig. 3, in some embodiments, the steeping mechanism 13 is provided with at least one steeping tank 130. In some embodiments, the soaking mechanism 13 is provided with a cover plate (not shown) for covering the ethanol solution in the soaking mechanism 13 to reduce the volatilization of the ethanol solution. In some embodiments, a cover plate is provided at the steeping tank 130 and covers the steeping tank 130.

Referring to fig. 2, 3, and 10, in some embodiments, the liquid-based sample processing apparatus 10 further includes a detection mechanism (not shown) for detecting whether the soaking mechanism 13 has the carriage 40 disposed therein and whether the carriage 40 has the sample disposed therein. By arranging the detection mechanism, the detection mechanism feeds back the detection result to the control system 15, and the control system 15 controls whether the transmission system 14 works or not according to the detection result. If the detection mechanism detects whether the carrier 40 is placed in the soaking mechanism 13, if the carrier 40 is placed in the soaking mechanism 13, the control system 15 controls the first gripper 145 to transfer the settled sample to the soaking mechanism 13 for soaking treatment, after the soaking treatment, the control system 15 controls the second gripper 146 to grip the carrier 40 to transfer the sample in the soaking mechanism 13 to the storage mechanism 16, so that the sample is transferred, if the detection mechanism detects that the carrier 40 is not placed in the soaking mechanism 13, the control system 15 controls the second gripper 146 to transfer the carrier 40 to the soaking mechanism 13, and then controls the first gripper 145 to transfer the settled sample to the soaking mechanism 13 for soaking treatment.

Referring to fig. 1 to 10, the working process of the embodiment of the present invention is as follows:

loading a centrifuge tube, pipette and sample container containing a sample into the first drawer 20 and pushing the first drawer 20 into the upper chamber;

the control system 15 controls the first manipulator 141 to transfer the sample container to the scanning mechanism for scanning, and then to the elution and blending mechanism 17 for elution and blending;

the control system 15 controls the second manipulator 142 of the transmission system 14 to transfer the centrifuge tube to the scanning mechanism for scanning, and then transfers the centrifuge tube to the tilting mechanism 19, controls the tilting mechanism 19 to tilt, and adds the gradient separation liquid into the centrifuge tube;

the control system 15 controls the sample adding mechanism 143 to be inserted into the liquid-transfer sucker, and then the sample is transferred into the elution and blending mechanism 17 to be sucked, and the sample is transferred into the centrifuge tube in an inclined state;

the control system 15 controls the second robot 142 to transfer the centrifuge tube into the elevator mechanism 144, and controls the elevator mechanism 144 to transfer the centrifuge tube into the centrifuge mechanism 18;

the control system 15 controls the centrifugal mechanism 18 to carry out centrifugation;

the control system 15 controls the second manipulator 142 to take out the centrifuge tube in the centrifuge mechanism 18 and transfer the centrifuge tube to the lifting mechanism 144, and controls the lifting mechanism 144 to transfer the centrifuge tube to the upper chamber;

controlling the sample adding mechanism 143 to be inserted into the liquid-transfer sucker so as to suck the sample in the centrifuge tube, and transferring the sample to the sedimentation component 30 at the sedimentation position 122 for sedimentation treatment;

controlling the third manipulator 148 to transfer the sedimentation assembly 30 to the pipe detaching mechanism 25 for pipe detaching;

controlling the detection mechanism to detect whether a slide basket exists in the soaking mechanism 13, if not, controlling the second gripper 146 to transfer the slide basket to the soaking mechanism 13, and if so, directly carrying out the next operation;

controlling the first gripper 145 to transfer the slide 32 obtained by the tube-disassembling process into the soaking mechanism 13 for soaking treatment, so that the slide 32 is placed in the slide basket;

controlling the second gripper 146 to transfer the sample in the soaking mechanism 13 to the storage mechanism 16;

the transfer channel 147 is controlled to operate to transfer the sample to the transfer port 1101.

It should be noted that the sample in this embodiment includes cells to be detected, such as exfoliated cervical cells, and the sample includes the cells to be detected, and the cells to be detected in the sample are obtained through processing, so as to facilitate further processing and observation and analysis of the cells to be detected. If the sedimentation treatment is performed, the test cells are sedimented and attached to the slide glass 32, and thus the test cells can be detected and analyzed.

Example two

Referring to fig. 12 and fig. 1, the difference between the present embodiment and the first embodiment is mainly that the position of the delivery port 1101 is different. In the first embodiment, the delivery opening 1101 is disposed on the left side plate 113. In the present embodiment, the transfer port 1101 is provided in the right side plate 114.

In addition to the above differences, the structure of the liquid-based specimen processing apparatus 10 and the specimen preparation method provided in this embodiment can be optimally designed with reference to the first embodiment, and will not be described in detail herein.

The above is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art can easily think of various equivalent modifications or replacements within the technical scope of the present invention, and these modifications or replacements should be covered within the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims (10)

1. The liquid-based sample processing equipment is characterized by comprising a shell, a bearing platform, a soaking mechanism, a transmission system and a control system;

the shell is provided with a containing cavity and a conveying port, and the conveying port is used for being communicated with a DNA ploid analysis device;

the bearing platform, the soaking mechanism and the transmission system are contained in the containing cavity;

the control system controls the transmission system to transfer the sample placed in the containing cavity so as to soak the sample, and transfers the soaked sample to the conveying port.

2. The liquid-based sample processing apparatus of claim 1, wherein the carrier platform is provided with a buffer location, and the soaking mechanism is disposed at the buffer location and used for containing an ethanol solution.

3. The liquid-based sample processing device of claim 2, wherein the transfer system comprises a transfer channel disposed within the receiving chamber and in communication with the transfer port to transfer the sample to the transfer port.

4. The liquid-based sample processing apparatus of claim 3, wherein the housing comprises a front side plate, a rear side plate, a left side plate, a right side plate, and a top plate, the containment chamber being enclosed by the front side plate, the rear side plate, the left side plate, the right side plate, and the top plate;

the conveying opening is formed in the left side plate or the right side plate.

5. The liquid-based sample processing device of claim 4, wherein the transport channel is disposed at a top of the load-bearing platform proximate to the rear side plate, and the transport channel extends along a direction from the left side plate to the right side plate;

and/or, the transmission channel is movably provided with a storage mechanism, the storage mechanism is provided with at least one storage groove, and ethanol solution is contained in the storage groove and is used for containing the soaked samples and transferring the samples to the conveying port through the transmission channel.

6. The liquid-based sample processing device according to any one of claims 1 to 5, wherein the carrier platform divides the receiving chamber into an upper chamber and a lower chamber, and a surface of the carrier platform facing the upper chamber is provided with a settling position and a buffering position.

7. The liquid-based sample processing device according to claim 6, wherein the liquid-based sample processing device comprises an elution and blending mechanism and a centrifugation mechanism, and the elution and blending mechanism and the soaking mechanism are arranged in the upper chamber; the centrifugal mechanism is arranged in the lower chamber.

8. The liquid-based sample processing device of claim 7, wherein the transport system comprises a transfer mechanism and a lift mechanism;

the transfer mechanism is used for transferring the sample to an elution and blending mechanism for elution and blending treatment and transferring the sample subjected to the elution and blending treatment to a centrifuge tube;

the lifting mechanism is used for transferring the centrifuge tube to the centrifugation mechanism for centrifugation and transferring the centrifuged sample to a sedimentation position for sedimentation.

9. The liquid-based sample processing apparatus of claim 8, wherein the transport system further comprises a first gripper and a second gripper, the first gripper configured to transfer the sedimentation-processed sample to the soaking mechanism containing an ethanol solution for soaking processing; the second gripper is used for transferring the soaked sample.

10. The liquid-based sample processing apparatus of any one of claims 1 to 5, wherein the housing comprises a front side plate, a rear side plate, a left side plate, a right side plate, and a top plate, the containment chamber being enclosed by the front side plate, the rear side plate, the left side plate, the right side plate, and the top plate;

the liquid-based sample processing equipment further comprises a first drawer, a second drawer and a third drawer, wherein the first drawer, the second drawer and the third drawer are arranged side by side at intervals and are movably mounted on the bearing platform along the direction from the front side plate to the rear side plate respectively;

the first drawer is for loading a centrifuge tube, a pipetting tip, and a sample container for delivering the centrifuge tube, the pipetting tip, and the sample container with a sample into the receiving cavity;

the second drawer is used for loading a sedimentation assembly to deliver the sedimentation assembly into the containing cavity;

the third drawer is used for loading a carrier to deliver the carrier into the containing cavity.

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