CN217348812U

CN217348812U - Kit for quantitative detection of endotoxin in nucleic acid sample

Info

Publication number: CN217348812U
Application number: CN202221462829.XU
Authority: CN
Inventors: 宋博; 杨赟; 汤辰翔
Original assignee: Shanghai Huanma Biopharmaceutical Co ltd
Current assignee: Shanghai Huanma Biopharmaceutical Co ltd
Priority date: 2022-06-13
Filing date: 2022-06-13
Publication date: 2022-09-02
Anticipated expiration: 2032-06-13

Abstract

The utility model discloses a kit for nucleic acid sample endotoxin quantitative determination, the power distribution box comprises a box body, there is the screw rod through bearing interlude movable mounting in the box, the screw rod is forward and reverse screw rod, fixed cover has cup jointed a gear on the screw rod, fixed mounting has the case on the internal face of box, the case is provided with two and is respectively the activity cup joint on the screw rod two screw threads to soon, a gear is located the right side of right side case, and common fixed mounting has the gag lever post between two cases, the gag lever post is provided with two and is front and back symmetric distribution, clamping device is installed to the screw thread on the screw rod. A kit for nucleic acid sample endotoxin quantitative determination, easy operation is convenient, can realize the centre gripping of all sample test tubes in the box through rotating the bull stick, can improve the stable effect of sample test tube through a shock pad and No. two shock pads, it is more convenient to use.

Description

Kit for quantitative detection of endotoxin in nucleic acid sample

Technical Field

The utility model relates to a kit technical field, in particular to a kit for nucleic acid sample endotoxin quantitative determination.

Background

The types of samples for pathogenic nucleic acid detection are tissues, blood, swabs, sputum and the like, which are common in clinic, the samples need to be transported to a designated place for detection after being extracted, and reagent storage boxes for storing the nucleic acid samples are often used during transportation.

When carrying out nucleic acid sample and storing, need press from both sides the nucleic acid sample test tube tightly, current nucleic acid sample kit when carrying out the centre gripping, needs one to carry out the centre gripping to the sample, and this kind of centre gripping mode is wasted time and energy, has reduced the working effect, and the upper and lower centre gripping effect of test tube differs, appears the phenomenon of test tube skew easily, and the shock attenuation effect that the sample test tube was deposited is not good, uses inconveniently. Therefore, we propose a kit for quantitative detection of endotoxin in nucleic acid samples.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a kit for quantitative determination of endotoxin in nucleic acid samples, which can effectively solve the problems in the background art.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

a kit for quantitatively detecting endotoxin in a nucleic acid sample comprises a box body, wherein a screw rod is movably arranged in the box body in an inserting mode through a bearing, the screw rod is a forward screw rod and a reverse screw rod, a gear is fixedly sleeved on the screw rod, storage boxes are fixedly arranged on the inner wall surface of the box body, the storage boxes are provided with two threads which are movably sleeved on the screw rod in two rotation directions respectively, the gear is positioned on the right side of the right storage box, a limiting rod is fixedly arranged between the two storage boxes together, the limiting rod is provided with two threads which are symmetrically distributed in the front and back direction, clamping devices are arranged on the screw rod in a threaded mode, the clamping devices are movably connected with the limiting rod in an inserting mode, the clamping devices are provided with two threads which are arranged on the screw rod in the two opposite rotation directions respectively, and are movably connected with the two storage boxes in an inserting mode respectively, the improved storage box comprises a box body, a rectangular groove, a set of storage groove, two, all be provided with the apron in the rectangular groove, two all alternate movable mounting on the apron has a set of knob, and is two sets of the knob respectively with two storage box threaded connection, hinge movable mounting has the bull stick on the right-hand member upper portion of box, the left end fixed mounting of bull stick has No. two gears, No. two gears are connected with gear drive.

Preferably, a set of ventilating grooves are formed in the inner side face of the storage box, the ventilating grooves are arranged to be three in each set and distributed in a front-back equidistant mode, a box cover is movably mounted at the upper end of the box body through hinges, a temperature sensor is fixedly mounted on the lower inner wall face of the box cover, and an indicator lamp is fixedly mounted at the upper end of the box cover.

Preferably, clamping device includes the slide, the upper end fixed mounting of slide has the connecting rod, the connecting rod is provided with threely and is equidistant distribution around, and is three equal fixed mounting has a set of horizontal pole on the connecting rod, the horizontal pole sets up to two and be upper and lower distribution of every group, the one end fixed mounting who keeps away from the connecting rod of horizontal pole has the arc to press from both sides.

Preferably, the sliding plate is installed on the screw in a threaded mode, the sliding plate is movably installed on the two limiting rods in an inserting mode, the cross rod is movably installed on the storage box in an inserting mode, and the arc-shaped clamp is located in the storage groove.

Preferably, ice storage boxes are fixedly mounted on the front inner wall surface and the rear inner wall surface of the box body, the two ice storage boxes are located between the two storage boxes, the two ice storage boxes are located on the front side and the rear side of the two clamping devices respectively, and the ventilation groove is located between the two cross rods which are opposite up and down.

Preferably, the storage tank sets up to every three and equidistance around being distributes, the tank bottom fixed mounting of storage tank has a shock pad, the lower extreme fixed mounting of apron has a set of No. two shock pads, No. two shock pads set up to every three and be located correspondingly with a shock pad, a shock pad is located the storage tank.

Compared with the prior art, the utility model discloses following beneficial effect has:

1. the utility model discloses in, through setting up clamping device, the connecting rod plays the effect of connecting slide and horizontal pole, through rotating the bull stick, makes the screw rod rotate, makes two slides move to the outside, makes connecting rod, horizontal pole and arc press from both sides to the outside removal, realizes the centre gripping work of sample test tube, and two relative arc clamps from top to bottom carry out the centre gripping to the test tube jointly, and the centre gripping effect is better, does not need one to carry out the centre gripping to the sample test tube, and the operation is simple and convenient more, has improved work efficiency.

2. The utility model discloses in, through setting up shock pad and No. two shock pads, shock pad and No. two shock pads play absorbing effect jointly, prevent that the sample test tube from rocking in the storage tank, improve the stable effect of sample test tube.

Drawings

FIG. 1 is a schematic diagram of the internal structure of a case of the kit for quantitative detection of endotoxin in a nucleic acid sample according to the present invention;

FIG. 2 is a sectional view of a part of the structure of a kit for quantitative detection of endotoxin in a nucleic acid sample according to the present invention;

FIG. 3 is a schematic structural diagram of a holding device of the kit for quantitative detection of endotoxin in a nucleic acid sample according to the present invention;

FIG. 4 is a schematic diagram of the external overall structure of the kit for quantitatively detecting endotoxin in a nucleic acid sample according to the present invention.

In the figure: 1. a box body; 2. a screw; 3. a first gear; 4. a storage box; 41. a limiting rod; 5. a clamping device; 6. a rectangular groove; 7. a storage tank; 8. a first shock pad; 9. a ventilation groove; 10. a cover plate; 11. a second shock pad; 12. a knob; 13. an ice bank; 14. a rotating rod; 15. a second gear; 16. a box cover; 17. a temperature sensor; 18. an indicator light; 51. a slide plate; 52. a connecting rod; 53. a cross bar; 54. an arc-shaped clamp.

Detailed Description

In order to make the technical means, creation features, achievement purposes and functions of the present invention easy to understand, the present invention is further described below with reference to the following embodiments.

In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "both ends", "one end", "the other end" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element to which the reference is made must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "connected," and the like are to be construed broadly, and for example, "connected" may be either fixedly connected or detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

As shown in figures 1-4, a kit for quantitative detection of endotoxin in a nucleic acid sample comprises a box body 1, a screw rod 2 is movably inserted and installed in the box body 1 through a bearing, the screw rod 2 is a forward and reverse screw rod, a gear 3 is fixedly sleeved on the screw rod 2, storage boxes 4 are fixedly installed on the inner wall surface of the box body 1, the storage boxes 4 are provided with two threads which are respectively movably sleeved on two rotating directions of the screw rod 2, the gear 3 is positioned on the right side of the right storage box 4, a limiting rod 41 is jointly and fixedly installed between the two storage boxes 4, the limiting rods 41 are provided with two threads which are symmetrically distributed front and back, clamping devices 5 are installed on the screw rod 2 through the threads, the clamping devices 5 are movably connected with the limiting rod 41 in an inserting manner, the two clamping devices 5 are respectively installed on the screw rod 2 through the threads with opposite rotating directions, the two clamping devices 5 are respectively movably connected with the two storage boxes 4 in an inserting manner, rectangular channel 6 has all been seted up to the upper end of two case 4, a set of storage tank 7 has all been seted up to the tank bottom surface of two rectangular channels 6, all be provided with apron 10 in two rectangular channels 6, all alternate movable mounting on two apron 10 and have a set of knob 12, two sets of knobs 12 respectively with two 4 threaded connection of case, hinge movable mounting has bull stick 14 on the right-hand member upper portion of box 1, the left end fixed mounting of bull stick 14 has No. two gears 15, No. two gears 15 are connected with the transmission of a gear 3.

A set of ventilation grooves 9 are formed in the inner side face of the storage box 4, the ventilation grooves 9 are arranged to be three in each set and distributed in a front-back equidistant mode, a box cover 16 is movably mounted at the upper end of the box body 1 through a hinge, a temperature sensor 17 is fixedly mounted on the lower inner wall face of the box cover 16, and an indicator light 18 is fixedly mounted at the upper end of the box cover 16. Temperature sensor 17 can detect the temperature situation in the box 1, and when temperature sensor 17 detected the temperature in the box 1 and crossed low or too high, pilot lamp 18 sent the light, reminded the staff in time to handle.

Clamping device 5 includes slide 51, and slide 51's upper end fixed mounting has connecting rod 52, and connecting rod 52 is provided with threely and is equidistant distribution around being, all fixed mounting has a set of horizontal pole 53 on the three connecting rod 52, and horizontal pole 53 sets up to two and be upper and lower distribution of every group, and the one end fixed mounting who keeps away from connecting rod 52 of horizontal pole 53 has arc-shaped clamp 54. The sliding plate 51 is installed on the screw rod 2 in a threaded mode, the sliding plate 51 is movably installed on the two limiting rods 41 in a penetrating mode, the cross rod 53 is movably installed on the storage box 4 in a penetrating mode, and the arc-shaped clamp 54 is located in the storage groove 7. Connecting rod 52 plays the effect of connecting slide 51 and horizontal pole 53, through rotating bull stick 14, makes screw rod 2 rotate, makes two slides 52 lateral motion, makes connecting rod 52, horizontal pole 53 and arc press from both sides 54 lateral shifting, realizes the centre gripping work of sample test tube, and two relative arc clamps from top to bottom carry out the centre gripping to the test tube jointly, and the centre gripping effect is better, simultaneously, do not need one to carry out the centre gripping to the sample test tube, and the operation is more simple and convenient, has improved work efficiency.

The front inner wall surface and the rear inner wall surface of the box body 1 are fixedly provided with ice storage boxes 13, the two ice storage boxes 13 are positioned between the two storage boxes 4, the two ice storage boxes 13 are respectively positioned at the front side and the rear side of the two clamping devices 5, and the ventilation groove 9 is positioned between the two cross rods 53 which are opposite up and down. The ice storage box 13 plays a role in storing ice cubes, and cold air of the ice cubes enters the storage groove 7 through the ventilation groove 9, so that the sample test tubes are stored at a proper temperature, and the storage time of the sample test tubes is prolonged.

Storage tank 7 sets up to every three and be the front and back equidistance distribution, and storage tank 7's tank bottom fixed mounting has a shock pad 8, and apron 10's lower extreme fixed mounting has a set of No. two shock pads 11, and No. two shock pads 11 set up to every three and be located correspondingly with a shock pad 8, and a shock pad 8 is located storage tank 7. No. one shock pad 8 and No. two shock pads 11 play absorbing effect jointly, prevent that the sample test tube from rocking in storage tank 7.

It should be noted that, the utility model relates to a kit for quantitative detection of endotoxin in nucleic acid sample, during the use, put the ice-cube in ice-storage box 13, put the sample test tube on shock pad 8 in storage tank 7, rotate bull stick 14 and make second gear 15 rotate, thus make first gear 3 and screw rod 2 rotate, make slide 51 move to one side that is close to storage tank 4, make connecting rod 52 and horizontal pole 53 move to one side that is close to storage tank 4, make arc-shaped clamp 54 centre gripping the sample test tube in storage tank 7, then put apron 10 in rectangular channel 6, through knob 12, fix apron 10 and storage tank 4 together, make the sample test tube be located between shock pad 8 and second shock pad 11; this device, the principle is simple, and easy operation is convenient, can realize the centre gripping of all sample test tubes in box 1 through rotating bull stick 14, through setting up ice-storage box 13 and ventilative groove 9, can increase the storage time of sample test tube, through setting up temperature sensor 17 and pilot lamp 18, when the temperature in box 1 is crossed lowly or when too high, can in time remind the staff to handle.

The basic principles and the main features of the invention and the advantages of the invention have been shown and described above. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. A kit for quantitative detection of endotoxin in a nucleic acid sample comprises a box body (1), and is characterized in that: there are screw rods (2) through bearing interlude movable mounting in the box (1), screw rod (2) are forward and reverse screw rod, fixed cover has connect gear (3) on screw rod (2), fixed mounting has case (4) on the internal face of box (1), case (4) are provided with two and are respectively the activity cup joint on screw rod (2) two revolve to the screw thread, gear (3) are located the right side of right side case (4), common fixed mounting has gag lever post (41) between two cases (4), gag lever post (41) are provided with two and are front and back symmetric distribution, threaded mounting has clamping device (5) on screw rod (2), clamping device (5) and gag lever post (41) interlude swing joint, clamping device (5) are provided with two and are respectively threaded mounting on screw rod (2) two revolve to opposite screw thread, two clamping device (5) alternates swing joint with two case (4) respectively, two rectangular channel (6), two have all been seted up to the upper end of case (4) rectangular channel (7), two have all been seted up to the tank bottom face of rectangular channel (6) all be provided with apron (10), two in rectangular channel (6) all alternate movable mounting on apron (10) has a set of knob (12), and is two sets of knob (12) respectively with two case (4) threaded connection, there is bull stick (14) on the right-hand member upper portion of box (1) through hinge movable mounting, the left end fixed mounting of bull stick (14) has No. two gears (15), No. two gears (15) are connected with a gear (3) transmission.

2. The kit according to claim 1, wherein the kit comprises: a set of ventilating grooves (9) are formed in the inner side face of the storage box (4), the ventilating grooves (9) are arranged to be three in each group and distributed equidistantly in the front and back direction, a box cover (16) is movably mounted at the upper end of the box body (1) through hinges, a temperature sensor (17) is fixedly mounted on the lower inner wall face of the box cover (16), and an indicator lamp (18) is fixedly mounted at the upper end of the box cover (16).

3. The kit according to claim 2, wherein the kit comprises: clamping device (5) include slide (51), the upper end fixed mounting of slide (51) has connecting rod (52), connecting rod (52) are provided with threely and are the equidistance around and distribute, three equal fixed mounting has a set of horizontal pole (53) on connecting rod (52), horizontal pole (53) set up to two and be about two of every group and distribute, the one end fixed mounting who keeps away from connecting rod (52) of horizontal pole (53) has arc to press from both sides clamp (54).

4. The kit according to claim 3, wherein the kit comprises: the sliding plate (51) is installed on the screw rod (2) in a threaded mode, the sliding plate (51) is installed on the two limiting rods (41) in a penetrating mode, the cross rod (53) is installed on the storage box (4) in a penetrating mode, and the arc-shaped clamp (54) is located in the storage groove (7).

5. The kit according to claim 4, wherein the kit comprises: the refrigerator is characterized in that ice storage boxes (13) are fixedly mounted on the front inner wall surface and the rear inner wall surface of the box body (1), the two ice storage boxes (13) are located between the two storage boxes (4), the two ice storage boxes (13) are located on the front side and the rear side of the two clamping devices (5) respectively, and the ventilation groove (9) is located between the two cross rods (53) which are opposite up and down.

6. The kit according to claim 5, wherein the kit comprises: storage tank (7) set up to every three and be around equidistance distribute, the tank bottom fixed mounting of storage tank (7) has a shock pad (8), the lower extreme fixed mounting of apron (10) has a set of No. two shock pads (11), No. two shock pads (11) set up to every three and be located correspondingly with a shock pad (8), shock pad (8) are located storage tank (7).