CN217265510U

CN217265510U - Protein purification post support frame

Info

Publication number: CN217265510U
Application number: CN202220761578.9U
Authority: CN
Inventors: 汪勇; 周红利; 刘悦
Original assignee: Wuhan Feien Biotechnology Co ltd
Current assignee: Wuhan Feien Biotechnology Co ltd
Priority date: 2022-04-02
Filing date: 2022-04-02
Publication date: 2022-08-23
Anticipated expiration: 2032-04-02

Abstract

The utility model discloses a protein purification post support frame, including the positioning bottom plate, the positioning bottom plate from left to right runs through in proper order the equidistance and has seted up the through-hole, positioning bottom plate upper portion movable mounting has the limiting plate, the limiting plate corresponds the through-hole position and runs through and has seted up spacing hole, spacing downthehole portion movable mounting has spacing pipe, spacing pipe upper portion bilateral symmetry is provided with the fly leaf. The toper reset spring that spacing socle portion set up can play the buffering purpose to the installation location of purification post, prevent that the purification post from receiving great power and damaging, the spacing pipe of setting is closed to be fixed a position of spacing pipe in the inside location of toper constant head tank through toper location gluey piece joint after pushing down, so as to reach the purpose of quick fixed purification post, simultaneously when changing the purification post, only need receive outside pulling force to the purification post and just can make toper location gluey piece break away from inside the toper constant head tank, make both sides fly leaf open and take out inside purification post.

Description

Protein purification post support frame

Technical Field

The utility model relates to an experiment fixing device technical field specifically is a protein purification post support frame.

Background

The separation and purification of proteins is widely used in life science research, and is an essential technique in this field. A typical eukaryotic cell may contain thousands of different proteins, some of which are stable at room temperature, and most of which are easily inactivated and degraded at room temperature, thus requiring low temperature purification and storage. To study a protein, the protein must first be purified from other proteins and non-protein molecules. What is essential in the separation and purification process of protein is the purification post, and the purification post price is higher, easily damages moreover, and general test-tube rack does not reach the purpose of fixed and temporary storage purification post, and in addition, the experimentation overlength just leads to protein denaturation inefficacy very easily, so need carry on convenient rapider when spacing fixed to the purification post. Therefore, a protein purification column support is now required.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a protein purification post support frame pushes down through inserting the purification post inside the back, and it is spacing to press from both sides tight to spacing pipe through the closure of fly leaf, protects the purification post through toper reset spring and protection pad simultaneously to solve the problem that proposes among the above-mentioned background art.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a protein purification post support frame, includes the locating bottom plate, the locating bottom plate from left to right runs through in proper order the equidistance and has seted up the through-hole, locating bottom plate upper portion movable mounting has the limiting plate, the limiting plate corresponds the through-hole position and runs through and has seted up spacing hole, spacing downthehole portion movable mounting has spacing pipe, spacing pipe upper portion bilateral symmetry is provided with the fly leaf.

Preferably, the lower surface of the positioning bottom plate is provided with a limiting connecting conduit corresponding to the through hole in a fitting manner, the left side and the right side of the upper surface of the positioning bottom plate are symmetrically and fixedly provided with supporting plates, and the center of the upper surface of each supporting plate is inwards provided with a positioning hole.

Preferably, the upper surface of the positioning bottom plate is provided with a conical return spring in a fitting manner corresponding to the through hole, and the top end of the conical return spring is provided with a limiting pipe in a fitting manner.

Preferably, the left side and the right side of the limiting plate are provided with bolt holes corresponding to the positioning holes in a penetrating mode, positioning bolts are movably bolted in the bolt holes, and the positioning bolts are movably bolted in the positioning holes.

Preferably, the position of the upper surface of the limiting plate corresponding to the limiting hole is inwards provided with a conical positioning groove, and the inner wall of the conical positioning groove is attached with an anti-skid rubber pad.

Preferably, the left side and the right side of the conical positioning groove on the upper surface of the limiting plate are symmetrically and fixedly provided with supporting rods, and the top ends of the supporting rods are provided with arc-shaped limiting rods.

Preferably, the outer surface of the limiting pipe is attached to the inner wall of the limiting hole in a sliding manner, and the position of the center of the bottom of the limiting pipe, which corresponds to the through hole, is communicated with and provided with the guide port limiting pipe.

Preferably, the protection pad is installed in the laminating of spacing intraductal wall of spacing pipe and the spacing intraductal wall of guide way, spacing outside of tubes fixed surface installs the baffle, surface mounting under the movable limiting plate of laminating of baffle upper surface.

Preferably, the left side and the right side of the upper surface of the limiting pipe are fixedly provided with connecting blocks, the left side and the right side of each connecting block are symmetrically provided with positioning shafts, the left inner wall and the right inner wall of the movable plate are provided with holes corresponding to the connecting blocks, and the movable plate is movably connected with the connecting blocks through the holes.

Preferably, the upper part of the outer surface of the movable plate is provided with a conical positioning rubber block corresponding to the conical positioning groove, and the outer surface of the conical positioning rubber block is movably clamped and mounted on an anti-skid rubber pad.

Compared with the prior art, the beneficial effects of the utility model are that:

1. through running through the through-hole of seting up in positioning bottom plate bottom makes purification column bottom guide port can both outstanding to positioning bottom plate lower part, makes jointing equipment can correspond to connect in purification column guide port position, avoids influencing the device, and positioning bottom plate bottom is provided with spacing connecting pipe simultaneously and can advances spacing protection to stretching out guide port to make the junction position unchangeable, still can carry out connection protection and the purpose of deriving behind spacing pipe and the spacing pipe translocation of guide port.

2. Spacing pipe is spacing with spacing hole come through the limiting plate that sets up, make spacing pipe rise with decline in-process can not take place the skew, the buffering purpose can be played to the installation of purification post to the toper reset spring that spacing socle portion set up simultaneously, prevent that the purification post from damaging, the spacing pipe of setting is inside the location of fixing spacing pipe inside the toper constant head tank through the toper location gluey piece joint after pushing down to the both sides fly leaf closure of both sides, so as to reach the purpose of quick fixed purification post, simultaneously when changing the purification post, only need receive outside pulling force to the purification post and just can make the toper location glue the piece break away from the toper constant head tank inside, make the both sides fly leaf open and take out inside purification post.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is an exploded view of the mounting structure of the limiting tube of the present invention;

fig. 3 is a schematic view of the overall structure of the limiting plate of the present invention;

fig. 4 is the overall structure split view of the limiting pipe of the utility model.

In the figure: 1. positioning a bottom plate; 2. a through hole; 3. a conical return spring; 4. the limiting connection pipe; 5. a support plate; 6. positioning holes; 7. a limiting plate; 8. a keyhole; 9. positioning a bolt; 10. a limiting hole; 11. a conical positioning groove; 12. an anti-slip rubber pad; 13. a support bar; 14. an arc-shaped limiting rod; 15. a limiting pipe; 16. a guide port limiting pipe; 17. a protection pad; 18. a baffle plate; 19. connecting blocks; 20. a movable plate; 21. and a conical positioning rubber block.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

The utility model provides a: the utility model provides a protein purification post support frame, as shown in figure 1, including locating baseplate 1, locating baseplate 1 from left to right runs through in proper order the equidistance and has seted up through-

hole

2, and 1 upper portion movable mounting of locating baseplate has limiting plate 7, and limiting plate 7 corresponds through-hole 2 positions and runs through and has seted up spacing hole 10, and the inside movable mounting in spacing hole 10 has spacing

pipe

15, and 15 upper portion bilateral symmetry of spacing pipe is provided with fly leaf 20.

Preferably, the lower surface of the positioning bottom plate 1 is provided with a limiting connecting pipe 4 corresponding to the position of the through hole 2 in a laminating manner, the left side and the right side of the upper surface of the positioning bottom plate 1 are symmetrically and fixedly provided with supporting plates 5, the center of the upper surface of each supporting plate 5 is inwards provided with a positioning hole 6, the guide port of the purification column can extend downwards into the limiting connecting pipe 4 through the arranged through hole 2, the limiting connecting pipe 4 protects and limits the guide port of the purification column, can be connected with the internal components of the purification equipment to complete the butt joint, can play the aim of the butt joint when the purification column is inserted into the limiting pipe 15 for fixing, limits the limiting plate 7 through the arranged supporting plate 5, and plays a role in holding and placing the limiting plate 7.

Further, 1 upper surface of positioning bottom plate corresponds 2 position laminating in through-hole and installs toper reset spring 3, and the surface mounting under the 3 top laminating of toper reset spring 15, the toper reset spring 3 that sets up plays the buffering purpose after 15 pushes down at spacing pipe, and what set up simultaneously plays the support purpose after 15 extraction at spacing pipe, makes 15 top positions of spacing pipe and limiting plate 7 upper surface parallel, makes things convenient for the installation of purification post, as shown in fig. 2.

Specifically, the limiting plate 7 left and right sides corresponds locating hole 6 position and has run through and has seted up keyhole 8, and the inside activity bolt in keyhole 8 has connect positioning bolt 9, and positioning bolt 9 activity bolt is to locating hole 6 inside, and the staff comes limiting plate 7 locking at backup pad 5 upper surface through rotatory keyhole 8, can demolish limiting plate 7 through demolising baffle 18 simultaneously, changes different spacing pipes 15.

Further, limiting plate 7 upper surface corresponds spacing hole 10 position and has inwards seted up toper constant head tank 11, antiskid rubber mat 12 is installed in the laminating of toper constant head tank 11 inner wall, spacing pipe 15 is carried on spacingly through the spacing hole 10 of seting up, toper constant head tank 11 and antiskid rubber mat 12 of seting up can cooperate toper location rubber block 21 to carry on spacingly to spacing pipe 15's in-service position, antiskid rubber mat 12 cooperates toper location rubber block 21 to play the mesh of antiskid anticreep simultaneously, a atress for offsetting toper reset spring 3 to spacing pipe 15, under the condition that does not have external atress, spacing pipe 15 can not bounce through toper location rubber block 21 after fixed.

Furthermore, the support rods 13 are symmetrically and fixedly installed at the left and right sides of the tapered positioning groove 11 on the upper surface of the limiting plate 7, the arc-shaped limiting rod 14 is installed at the top end of the support rod 13, the support rod 13 and the arc-shaped limiting rod 14 can assist in fixing the movable plates 20, and the movable plates 20 are stacked after the movable plates 20 are opened, so that adjacent movable plates 20 are not stacked, as shown in fig. 2 and 3.

It is worth to say, the outer surface of the limiting pipe 15 is attached to the inner wall of the limiting hole 10 and is slidably mounted, the position of the center of the bottom of the limiting pipe 15, which corresponds to the through hole 2, is communicated with the guide port limiting pipe 16, the positions of the limiting pipe 15 and the guide port limiting pipe 16 are limited by the limiting hole 10, so that the guide port limiting pipe 16 can be stably abutted to the through hole 2 to be inserted, and the guide port of the purification column can be more stably extended.

In addition, the protection pad 17 is installed in the laminating of spacing pipe 15 and the 16 inner walls of the spacing pipe of lead mouth, spacing 15 outer fixed surface installs baffle 18, surface mounting under the limiting plate 7 of surface activity laminating on baffle 18, the protection pad 17 of setting has and protects the purification post, reduce the damage of purification post in the at utmost, promote work efficiency, the baffle 18 of setting simultaneously when spacing pipe 15 receives the power rebound of toper reset spring 3, spacing pipe 15 is carried on spacingly, make spacing 15 top of pipe and limiting plate 7 go up with the last parallel after the stop motion, convenient next time installation purification post.

Preferably, the left side and the right side of the upper surface of the limiting pipe 15 are fixedly provided with a connecting block 19, the left side and the right side of the connecting block 19 are symmetrically provided with a positioning shaft, the left inner wall and the right inner wall of the movable plate 20 are provided with a hole corresponding to the connecting block 19, the movable plate 20 is movably connected with the connecting block 19 through the hole, the positioning shafts on the two sides of the connecting block 19 are movably clamped with the holes on the inner wall of the movable plate 20, so that the movable plate 20 can be selected by taking the positioning shaft as a center, and the use position of the movable plate 20 is ensured.

Further, the upper portion of the outer surface of the movable plate 20 is provided with a conical positioning rubber block 21 corresponding to the conical positioning groove 11, the outer surface of the conical positioning rubber block 21 is movably clamped and mounted to the anti-skid rubber pad 12, and the set conical positioning rubber block 21 is pressed down by the purification column insertion limiting pipe 15 and is limited by the conical positioning groove 11 and the limiting hole 10, so that the movable plate 20 is retracted inwards, and the inner wall of the movable plate 20 can clamp the outer surface of the purification column to limit the purification column, as shown in fig. 4.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a protein purification post support frame which characterized in that: including positioning bottom plate (1), positioning bottom plate (1) from left to right runs through in proper order equidistance and has seted up through-hole (2), positioning bottom plate (1) upper portion movable mounting has limiting plate (7), limiting plate (7) correspond through-hole (2) position and run through and have seted up spacing hole (10), spacing hole (10) inside movable mounting has spacing pipe (15), spacing pipe (15) upper portion bilateral symmetry is provided with fly leaf (20).

2. The protein purification column support of claim 1, wherein: the positioning bottom plate (1) lower surface corresponds through-hole (2) position laminating and installs spacing connecting pipe (4), positioning bottom plate (1) upper surface left and right sides symmetry fixed mounting has backup pad (5), locating hole (6) have inwards been seted up at backup pad (5) upper surface center.

3. The protein purification column support of claim 2, wherein: the upper surface of the positioning bottom plate (1) is attached to a position corresponding to the through hole (2) and provided with a conical reset spring (3), and the top end of the conical reset spring (3) is attached to a limiting pipe (15) and is installed on the lower surface.

4. The protein purification column support of claim 3, wherein: the position of the left side and the right side of the limiting plate (7) corresponding to the positioning hole (6) is provided with a bolt hole (8) in a penetrating mode, a positioning bolt (9) is movably bolted in the bolt hole (8), and the positioning bolt (9) is movably bolted in the positioning hole (6).

5. The protein purification column support of claim 1, wherein: the upper surface of the limiting plate (7) is inwards provided with a conical positioning groove (11) corresponding to the position of the limiting hole (10), and the inner wall of the conical positioning groove (11) is attached with an anti-skid rubber pad (12).

6. The protein purification column support of claim 5, wherein: the supporting rods (13) are symmetrically and fixedly mounted on the left side and the right side of the conical positioning groove (11) in the upper surface of the limiting plate (7), and arc-shaped limiting rods (14) are arranged at the top ends of the supporting rods (13).

7. The protein purification column support of claim 1, wherein: spacing pipe (15) surface laminating spacing hole (10) inner wall slidable mounting, spacing pipe (15) bottom center corresponds through-hole (2) position intercommunication and installs spacing pipe of lead mouthful (16).

8. The protein purification column support of claim 7, wherein: spacing pipe (15) and the laminating of leading mouthful spacing pipe (16) inner wall and installing protection pad (17), spacing pipe (15) outer fixed surface installs baffle (18), baffle (18) upper surface activity laminating limiting plate (7) lower surface mounting.

9. The protein purification column support of claim 8, wherein: spacing pipe (15) upper surface left and right sides fixed mounting has connecting block (19), the left and right sides symmetry of connecting block (19) is provided with the location axle, the hole is seted up to inner wall correspondence connecting block (19) about fly leaf (20), fly leaf (20) clearing hole and connecting block (19) swing joint.

10. The protein purification column support of claim 9, wherein: the outer surface upper portion of the movable plate (20) is provided with a conical positioning rubber block (21) corresponding to the conical positioning groove (11), and the outer surface of the conical positioning rubber block (21) is movably clamped and installed on the anti-skid rubber pad (12).