CN217242377U

CN217242377U - Adhesion-preventing 3D organoid delivery device

Info

Publication number: CN217242377U
Application number: CN202220288349.XU
Authority: CN
Inventors: 张晶然; 张登; 程婉莹
Original assignee: Shanghai Haobai Biotechnology Co ltd
Current assignee: Shanghai Haobai Biotechnology Co ltd
Priority date: 2022-02-14
Filing date: 2022-02-14
Publication date: 2022-08-23
Anticipated expiration: 2032-02-14

Abstract

The utility model discloses a prevent glutinous 3D class organ conveyor relates to medical technical field, including the conveyor casing, there is first apron upper end rear side of conveyor casing through hinge connection, conveyor casing and first apron front end middle part fixedly connected with tool to lock, the inside wall fixedly connected with insulating layer of conveyor casing, the inner chamber upside left and right sides fixedly connected with branch of conveyor casing, the inner chamber activity of conveyor casing is placed and is carried and place the casing, carry and place the both ends upper portion fixedly connected with lap board about of casing. This prevent adhesive 3D organoid conveyor, overall structure through equipment, overall structure is when storing the culture organ, and the organ of cultivateing is transported in storage to one to avoid the organ to place together, and appear the phenomenon that the adhesion is in the same place.

Description

Adhesion-preventing 3D organoid delivery device

Technical Field

The utility model relates to the field of medical technology, especially, relate to prevent glutinous 3D class organ conveyor who links.

Background

Organoids belong to three-dimensional (3D) cell cultures, which contain some key properties that represent the organ. Such in vitro culture systems include a self-renewing stem cell population that can be differentiated into a plurality of organ-specific cell types, that share similar spatial organization with the corresponding organ and that reproduce a portion of the function of the corresponding organ, thereby providing a highly physiologically relevant system that can readily adhere to organs when delivered in 3D organoids.

In the use process of the existing 3D organoid conveying device for preventing adhesion, when organs are conveyed to a destination to be taken out, the organ is taken out in a whole structure, so that the 3D organoid conveying device for preventing adhesion is provided.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving the defects existing in the prior art, and providing a 3D organoid conveying device for preventing adhesion. Its advantage lies in overall structure when the organ is cultivateed in the storage, stores the organ of a cultivation of the inside storage of transportation casing for one to avoid the organ to place together, and the phenomenon that appears gluing and be in the same place.

In order to achieve the above purpose, the utility model adopts the following technical scheme: the anti-adhesion 3D type organ conveying device comprises a conveying device shell, wherein the rear side of the upper end of the conveying device shell is connected with a first cover plate through a hinge, the middle parts of the front ends of the conveying device shell and the first cover plate are fixedly connected with a lock, the inner side wall of the conveying device shell is fixedly connected with a heat insulation layer, the left side and the right side of the upper side of an inner cavity of the conveying device shell are fixedly connected with supporting rods, a conveying and placing shell is movably placed in the inner cavity of the conveying device shell, the upper parts of the left end and the right end of the conveying and placing shell are fixedly connected with lap plates, and the lap plates are movably placed at the upper ends of the supporting rods;

the lower end of the inner cavity of the conveying and placing shell is fixedly connected with a supporting block, a supporting plate is movably placed in the inner cavity of the conveying and placing shell, a buffer spring is fixedly connected between the lower end of the supporting plate and the lower end of the inner cavity of the conveying and placing shell, a storage shell is movably placed at the upper end of the supporting plate, and the upper end of the storage shell is connected with a second cover plate through a lock catch;

storage shell inner chamber lower extreme fixedly connected with stock solution casing, the inside activity of stock solution casing has been placed and has been stored and transport the casing, store the outside lower part fixedly connected with spacing ring of transporting the casing, the lower part of storing and transporting the casing is opened there is the through-hole, the outside activity of storing and transporting the casing has cup jointed the sealing ring, store the outside upper end fixedly connected with go-between of transporting the casing, the spring has been cup jointed between go-between and sealing ring in the outside of storing and transporting the casing.

Through the technical scheme: when the device is used, the first cover plate is firstly opened, then the conveying and placing shell is taken out, then the ice bag is placed on the inner side wall of the heat insulation layer, then the conveying and placing shell is placed, then the second cover plate is opened, the storage and transportation shell is taken out, nutrient liquid is injected into the storage and transportation shell, the nutrient liquid is injected into the correspondingly placed liquid storage shell, then the storage and transportation shell is placed in the liquid storage shell, and then the second cover plate is covered to complete the placement of the organ;

when the second cover plate is covered, the second cover plate can downwards extrude the storage and transportation shell, so that the sealing ring is upwards displaced, and each through hole is exposed, so that the culture solution in the liquid storage shell is communicated with the interior of the storage and transportation shell;

and when the organ is taken out to needs, open the second apron, then the hand (hold) of sealed lid upper end is held to the manual work to propose and store and transport the casing, at this moment the lower part of sealing ring can not receive the effect of power, under the spring action, and make sealed ring move down, thereby sealed each through-hole, make the storage transport casing inside can remain a large amount of culture solution when taking out, avoid cultivateing the meeting by the damage of organ.

The utility model discloses further set up to, the inside wall fixedly connected with rubber seal ring of sealing ring.

Through the technical scheme: the rubber sealing ring can increase the sealing performance of the sealing ring.

The utility model discloses further set up to, it has sealed lid to store the inner chamber upper portion of transporting the casing through the screw-thread grafting, the upper end fixedly connected with hand (hold) of sealed lid.

Through the technical scheme: the handle that sealed upper end set up can be convenient for store the taking of transporting the casing.

The utility model discloses further set up to, the stock solution casing is equipped with a plurality of, the even range of stock solution casing is connected at storage casing inner chamber lower extreme.

Through the technical scheme: the culture solution is stored in the liquid storage shell.

The utility model discloses further set up to, the through-hole is equipped with a plurality of, the even division of through-hole is storing and is transporting the casing lower part.

Through the technical scheme: the through-hole can make the inside culture solution of stock solution casing with store and transport the inside liquid of casing and be linked together.

The utility model discloses further set up to, the external diameter of sealing ring is greater than the internal diameter of stock solution casing.

Through the technical scheme: when the storage and transportation shell is displaced downwards, the sealing ring can be displaced to the upper part of the storage and transportation shell.

The utility model discloses further set up to, buffer spring and supporting shoe all are equipped with a plurality ofly, the even range of buffer spring is placed between the casing inner chamber lower extreme at the lower extreme of backup pad and transport, and the even range of supporting shoe is placed casing inner chamber lower extreme at the transport.

Through the technical scheme: the buffer spring can play a role of buffering.

The utility model has the advantages that:

1. this prevent adhesive 3D organoid conveyor, overall structure through equipment, overall structure is when storing the culture organ, and the organ of cultivateing is transported in storage to one to avoid the organ to place together, and appear the phenomenon that the adhesion is in the same place.

2. This prevent adhesive 3D organoid conveyor, through being provided with the structure of storing transportation casing and sealing ring, when needing to take out the organ, open the second apron, then the hand (hold) of manual sealed lid upper end of holding, thereby it transports the casing to propose to store, at this moment, the lower part of sealing ring can not receive the effect of power, under the spring action, and make sealed hoop displacement down, thereby sealed each through-hole, inside can remain a large amount of culture solution when making the storage transport casing take out, avoid cultivateing can be damaged of organ.

Drawings

Fig. 1 is a schematic view of the overall structure of the adhesion-preventing 3D organoid delivery device of the present invention;

fig. 2 is a schematic sectional view of a housing of the anti-adhesion 3D organoid delivery device of the present invention;

fig. 3 is an enlarged view of the anti-adhesion 3D organoid delivery apparatus of the present invention at a in fig. 2;

fig. 4 is the utility model provides a prevent that adhesion's 3D organoid conveyor's storage transports casing overall structure chart.

In the figure: 1. a conveyor housing; 2. a first cover plate; 3. a lock; 4. a thermal insulation layer; 5. conveying and placing the shell; 6. a support block; 7. a buffer spring; 8. a support plate; 9. a lap plate; 10. a strut; 11. a liquid storage shell; 12. a second cover plate; 13. a storage case; 14. storing the transport shell; 15. a seal ring; 16. a rubber seal ring; 17. a connecting ring; 18. a sealing cover; 19. a spring; 20. a limiting ring; 21. and a through hole.

Detailed Description

The technical solution of the present patent will be described in further detail with reference to the following embodiments.

Reference will now be made in detail to embodiments of the present patent, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present patent and are not to be construed as limiting the present patent.

In the description of this patent, it is to be understood that the terms "center," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientations and positional relationships indicated in the drawings for the convenience of describing the patent and for the simplicity of description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are not to be considered limiting of the patent.

In the description of this patent, it is noted that unless otherwise specifically stated or limited, the terms "mounted," "connected," and "disposed" are to be construed broadly and can include, for example, fixedly connected, disposed, detachably connected, disposed, or integrally connected and disposed. The specific meaning of the above terms in this patent may be understood by those of ordinary skill in the art as appropriate.

Referring to fig. 1-4, the anti-adhesion 3D organ transporter comprises a transporter housing 1, wherein a first cover plate 2 is connected to the rear side of the upper end of the transporter housing 1 through a hinge, a lock 3 is fixedly connected to the middle of the front ends of the transporter housing 1 and the first cover plate 2, a heat insulation layer 4 is fixedly connected to the inner side wall of the transporter housing 1, supporting rods 10 are fixedly connected to the left and right sides of the upper side of the inner cavity of the transporter housing 1, a transporting and placing housing 5 is movably placed in the inner cavity of the transporter housing 1, overlapping plates 9 are fixedly connected to the upper portions of the left and right ends of the transporting and placing housing 5, and the overlapping plates 9 are movably placed at the upper ends of the supporting rods 10;

the lower end of the inner cavity of the conveying and placing shell 5 is fixedly connected with a supporting block 6, a supporting plate 8 is movably placed in the inner cavity of the conveying and placing shell 5, a buffer spring 7 is fixedly connected between the lower end of the supporting plate 8 and the lower end of the inner cavity of the conveying and placing shell 5, a plurality of buffer springs 7 and a plurality of supporting blocks 6 are arranged, the buffer springs 7 are uniformly arranged between the lower end of the supporting plate 8 and the lower end of the inner cavity of the conveying and placing shell 5, the supporting blocks 6 are uniformly arranged at the lower end of the inner cavity of the conveying and placing shell 5, a storage shell 13 is movably placed at the upper end of the supporting plate 8, and the upper end of the storage shell 13 is connected with a second cover plate 12 through a lock catch;

the lower end of the inner cavity of the storage shell 13 is fixedly connected with a liquid storage shell 11, a plurality of liquid storage shells 11 are arranged, the liquid storage shell 11 is uniformly arranged and connected at the lower end of the inner cavity of the storage shell 13, the storage and transportation shell 14 is movably arranged in the liquid storage shell 11, the lower part of the outer side of the storage and transportation shell 14 is fixedly connected with a limiting ring 20, the lower part of the storage and transportation shell 14 is provided with a through hole 21, a plurality of through holes 21 are arranged, the through holes 21 are uniformly formed in the lower part of the storage and transportation shell 14, the through holes 21 can enable the culture solution in the liquid storage shell 11 to be communicated with the liquid in the storage and transportation shell 14, a sealing ring 15 is movably sleeved on the outer side of the storage and transportation shell 14, a connecting ring 17 is fixedly connected to the upper end of the outer side of the storage and transportation shell 14, a spring 19 is sleeved on the outer side of the storage and transfer shell 14 between the connecting ring 17 and the sealing ring 15.

Further, referring to fig. 2-3, the inner side wall of the sealing ring 15 is fixedly connected with a rubber sealing ring 16, the outer diameter of the sealing ring 15 is larger than the inner diameter of the liquid storage shell 11, and the sealing performance of the sealing ring 15 can be improved by the rubber sealing ring 16.

Referring to fig. 3, a sealing cover 18 is inserted into an upper portion of the inner cavity of the storage and transportation housing 14 through a thread, a handle is fixedly connected to an upper end of the sealing cover 18, and the handle arranged at the upper end of the sealing cover 18 can facilitate taking of the storage and transportation housing 14.

The working principle is as follows: when the device is used, the first cover plate 2 is firstly opened, the conveying and placing shell 5 is taken out, then the ice bag is placed on the inner side wall of the heat insulation layer 4, then the conveying and placing shell 5 is placed, then the second cover plate 12 is opened, the storage and transportation shell 14 is taken out, nutrient liquid is injected into the storage and transportation shell 14, the nutrient liquid is injected into the correspondingly placed liquid storage shell 11, then the storage and transportation shell 14 is placed in the liquid storage shell 11, and then the second cover plate 12 is covered to complete the placement of organs;

when the second cover plate 12 is covered, the second cover plate 12 presses the storage and transportation shell 14 downwards, so that the sealing ring 15 is displaced upwards, and each through hole 21 is exposed, so that the culture solution inside the storage shell 11 is communicated with the inside of the storage and transportation shell 14;

and when the organ needs to be taken out, the second cover plate 12 is opened, then the handle at the upper end of the sealing cover 18 is manually held, so that the storage and transportation shell 14 is put forward, the lower part of the sealing ring 15 is not acted by force, the sealing ring 15 is enabled to displace downwards under the action of the spring 19, each through hole 21 is sealed, a large amount of culture solution can be remained inside the storage and transportation shell 14 when the storage and transportation shell is taken out, and the organ culture can be prevented from being damaged.

The above, only be the concrete implementation of the preferred embodiment of the present invention, but the protection scope of the present invention is not limited thereto, and any person skilled in the art is in the technical scope of the present invention, according to the technical solution of the present invention and the utility model, the concept of which is equivalent to replace or change, should be covered within the protection scope of the present invention.

Claims

1. The anti-adhesion 3D type organ conveying device comprises a conveying device shell (1) and is characterized in that the rear side of the upper end of the conveying device shell (1) is connected with a first cover plate (2) through a hinge, the middle parts of the front ends of the conveying device shell (1) and the first cover plate (2) are fixedly connected with a lock (3), the inner side wall of the conveying device shell (1) is fixedly connected with a heat insulation layer (4), the left side and the right side of the upper side of an inner cavity of the conveying device shell (1) are fixedly connected with supporting rods (10), a conveying placing shell (5) is movably placed in the inner cavity of the conveying device shell (1), the upper parts of the left end and the right end of the conveying placing shell (5) are fixedly connected with a lapping plate (9), and the lapping plate (9) is movably placed at the upper ends of the supporting rods (10);

the lower end of the inner cavity of the conveying and placing shell (5) is fixedly connected with a supporting block (6), a supporting plate (8) is movably placed in the inner cavity of the conveying and placing shell (5), a buffer spring (7) is fixedly connected between the lower end of the supporting plate (8) and the lower end of the inner cavity of the conveying and placing shell (5), a storage shell (13) is movably placed at the upper end of the supporting plate (8), and the upper end of the storage shell (13) is connected with a second cover plate (12) through a lock catch;

store casing (13) inner chamber lower extreme fixedly connected with stock solution casing (11), the inside activity of stock solution casing (11) has been placed and has been stored and transport casing (14), the outside lower part fixedly connected with spacing ring (20) of transporting casing (14) are stored, the lower part of transporting casing (14) is opened and has been had through-hole (21) to store, sealing ring (15) have been cup jointed in the outside activity of storing and transporting casing (14), the outside upper end fixedly connected with go-between (17) of storing and transporting casing (14), spring (19) have been cup jointed between go-between (17) and sealing ring (15) in the outside of storing and transporting casing (14).

2. The adhesion-prevention 3D organoid delivery device according to claim 1, wherein a rubber sealing ring (16) is fixedly attached to the inner sidewall of the sealing ring (15).

3. The adhesion-prevention 3D organoid delivery apparatus according to claim 1, wherein a sealing cover (18) is inserted into the upper portion of the inner cavity of the storage and transportation housing (14) by screw threads, and a handle is fixedly connected to the upper end of the sealing cover (18).

4. The adhesion-prevention 3D organoid delivery device according to claim 1, wherein the reservoir housing (11) is provided in a plurality of numbers, and the reservoir housing (11) is connected to the lower end of the inner cavity of the reservoir housing (13) in a uniform arrangement.

5. The adhesion-prevention 3D organoid delivery device according to claim 1, wherein the through-holes (21) are provided in a plurality, and the through-holes (21) are uniformly opened at the lower part of the storage and transportation housing (14).

6. The adhesion prevention 3D organoid delivery device of claim 1, wherein the sealing ring (15) has an outer diameter greater than an inner diameter of the reservoir housing (11).

7. The adhesion prevention 3D organoid delivery apparatus according to claim 1, wherein a plurality of the buffer springs (7) and the support blocks (6) are provided, the buffer springs (7) are uniformly arranged between the lower end of the support plate (8) and the lower end of the inner cavity of the delivery and placement housing (5), and the support blocks (6) are uniformly arranged at the lower end of the inner cavity of the delivery and placement housing (5).