CN217070058U - Bag cleaning equipment and bag processing system - Google Patents
Bag cleaning equipment and bag processing system Download PDFInfo
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- CN217070058U CN217070058U CN202121520721.7U CN202121520721U CN217070058U CN 217070058 U CN217070058 U CN 217070058U CN 202121520721 U CN202121520721 U CN 202121520721U CN 217070058 U CN217070058 U CN 217070058U
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Abstract
The present disclosure provides a bag body cleaning apparatus, a bag body contains blood and/or blood derivatives in a frozen state, including: a first rinsing device for supplying a first type of rinsing liquid for rinsing the surface of the bag body; second rinsing means for supplying a second type of rinsing liquid for rinsing the surface of the bag body; a second gas supply device for supplying gas to the surface of the bag body flushed by the second flushing device so as to remove the liquid on the surface of the bag body; and a conveying device for conveying the bag bodies from the first flushing device to the second gas supply device, wherein the microbial load on the surface of the bag bodies flushed with the second type of flushing liquid is less than the microbial load on the surface of the bag bodies flushed with the first type of flushing liquid, and the first type of flushing liquid and the second type of flushing liquid are different types of water. The present disclosure also provides a bag handling system.
Description
Technical Field
The present disclosure relates to a bag cleaning apparatus and a bag processing system.
Background
In the process of transferring blood or blood derivatives, for example, blood plasma is generally placed in a bag body and frozen, and the transfer of the blood plasma is realized by transporting the frozen blood plasma bag. However, during the freezing, transportation and subsequent storage of the plasma bag, the outer surface of the plasma bag may be contaminated by exposure to the external environment.
Therefore, the outer surface of the plasma bag needs to be disinfected and cleaned before plasma raw materials are added in the blood product production, and ethanol is generally used for disinfection in the disinfection process. However, ethanol belongs to flammable and explosive objects, has certain potential safety hazards, the storage, the use and the waste liquid discharge of the ethanol have to meet the requirements on safety, environmental protection, health and the like, and special hardware facilities (such as storage tanks and pipelines) are needed to realize ethanol disinfection, so the material cost and the management cost of production are high.
Therefore, it is one of the technical problems to be solved by the present disclosure to avoid using a liquid such as ethanol for sterilization and cleaning and to ensure the cleaning effect.
Moreover, the existing plasma bag has low processing efficiency, high degree of manual participation in part of procedures, and increased interference and pollution risks caused by human factors, and cannot meet the requirements of rapid processing and GMP standard.
SUMMERY OF THE UTILITY MODEL
In order to solve one of the above technical problems, the present disclosure provides a bag cleaning apparatus and a bag processing system.
According to one aspect of the present disclosure, there is provided a bag cleaning apparatus, the bag containing blood and/or blood derivatives in a frozen state, characterized by comprising:
a first rinsing device for supplying a first type of rinsing liquid for rinsing a surface of the bag body;
a second rinsing device for supplying a second type of rinsing liquid for rinsing the surface of the bag body;
a second gas supply device for supplying gas to the surface of the bag body after the second flushing device flushes so as to remove the liquid from the surface of the bag body; and
a conveying device for conveying the bag bodies from the first flushing device to the second gas supply device,
wherein a microbial load of the surface of the bag body after being flushed with the second type of flushing liquid is less than a microbial load of the surface of the bag body after being flushed with the first type of flushing liquid.
The bag body cleaning apparatus according to at least one embodiment of the present disclosure further includes a first gas supply device for supplying gas to the surface of the bag body after the first rinsing device rinses the surface of the bag body so as to remove liquid from the surface of the bag body.
According to the bag body cleaning equipment of at least one embodiment of the present disclosure, the first washing device includes a first upper side washing device and a first lower side washing device, and the first upper side washing device and the first lower side washing device are respectively used for washing at least the upper side surface and the lower side surface of the bag body.
According to the bag body cleaning apparatus of at least one embodiment of the present disclosure, the first flushing device and the first gas supplying device are accommodated in the first cleaning chamber.
According to the bag body cleaning equipment of at least one embodiment of the present disclosure, the second washing device includes a second upper side washing device and a second lower side washing device, and the second upper side washing device and the second lower side washing device are respectively used for washing at least the upper side surface and the lower side surface of the bag body.
According to the bag body cleaning apparatus of at least one embodiment of the present disclosure, the second flushing device and the second gas supply device are housed in the second cleaning chamber.
According to the bag body cleaning apparatus of at least one embodiment of the present disclosure, the height at which the bag body is washed by the second washing device is higher than or equal to the height at which the bag body is washed by the first washing device.
The bag body cleaning apparatus according to at least one embodiment of the present disclosure, further comprising a third rinsing device disposed between the first rinsing device and the second rinsing device and for supplying a third type of rinsing liquid for rinsing the surface of the bag body,
wherein the conveying device conveys the bag bodies from the first rinsing device to the third rinsing device and the second rinsing device in sequence, and the microbial load on the surface of the bag bodies rinsed with the third type of rinsing liquid is less than or equal to the microbial load on the surface of the bag bodies rinsed with the first type of rinsing liquid and is equal to or greater than the microbial load on the surface of the bag bodies rinsed with the second type of rinsing liquid.
The bag body cleaning apparatus according to at least one embodiment of the present disclosure further includes a third gas supply device for supplying gas to the surface of the bag body after the third rinsing device rinses so as to remove liquid from the surface of the bag body.
According to the bag body cleaning apparatus of at least one embodiment of the present disclosure, the cleanliness of the gas supplied from the second gas supply device is higher than the cleanliness of the gas supplied from the third gas supply device.
According to the bag body cleaning equipment of at least one embodiment of the present disclosure, the third washing device includes a third upper side washing device and a third lower side washing device, and the third upper side washing device and the third lower side washing device are respectively used for washing at least the upper side surface and the lower side surface of the bag body.
According to the bag body cleaning apparatus of at least one embodiment of the present disclosure, the third flushing device and the third gas supply device are housed in a third cleaning chamber.
According to the bag cleaning apparatus of at least one embodiment of the present disclosure, the height at which the bags are washed by the third washing device is higher than or equal to the height at which the bags are washed by the first washing device and lower than or equal to the height at which the bags are washed by the second washing device.
According to the bag cleaning device according to at least one embodiment of the present disclosure, the temperature of the first type of flushing liquid provided by the first flushing device and/or the temperature of the second type of flushing liquid provided by the second flushing device is controlled so as to pre-separate the bag from the frozen state of the blood and/or blood derivatives contained in the bag.
According to the bag cleaning apparatus of at least one embodiment of the present disclosure, the pressure of the first type of rinsing liquid provided by the first rinsing device and/or the pressure of the second type of rinsing liquid provided by the second rinsing device can be adjusted based on the conveying speed of the conveying device.
According to the bag cleaning apparatus of at least one embodiment of the present disclosure, the second type of rinse liquid after rinsing the bag is collected to be used as the first type of rinse liquid supplied by the first rinsing device.
According to the bag cleaning apparatus of at least one embodiment of the present disclosure, the third type of rinse liquid after rinsing the bag is collected to be used as the first type of rinse liquid supplied by the first rinsing device.
According to still another aspect of the present disclosure, there is also provided a bag body processing system including:
the bag body cleaning device comprises a bag body cleaning device, a bag body cleaning device and a control device, wherein the bag body cleaning device is used for cleaning the surface of the bag body;
a bag breaking device for breaking the cleaned bag body and separating the blood and/or blood derivatives contained in the bag body from the bag body; and
a transfer device for transferring the bag bodies in the bag body cleaning apparatus and from the bag body cleaning apparatus to the bag breaking apparatus.
The bag handling system according to at least one embodiment of the present disclosure further comprises a storage device for storing the blood and/or blood-derived product received from the bag breaking apparatus.
The bag processing system according to at least one embodiment of the present disclosure further comprises a transfer device for transferring the bags containing blood and/or blood derivatives in a frozen state to the conveying device, so as to clean the bags by the bag cleaning apparatus.
The bag handling system according to at least one embodiment of the present disclosure further comprises a conveying device for conveying bags containing blood and/or blood derivatives in a frozen state, and the transfer device is a robotic arm that grabs the bags from the conveying device.
In accordance with at least one embodiment of the present disclosure, the transport apparatus transports the pouches in a direction from one side of the robotic arm to the other side, the robotic arm transferring the pouches to the conveyor in an alternating manner of grasping on the one side and the other side.
Drawings
The accompanying drawings, which are included to provide a further understanding of the disclosure and are incorporated in and constitute a part of this specification, illustrate exemplary embodiments of the disclosure and together with the description serve to explain the principles of the disclosure.
Figure 1 shows a cross-sectional view of a pouch cleaning apparatus according to one embodiment of the present disclosure.
Figure 2 shows a schematic view of a pouch cleaning apparatus according to one embodiment of the present disclosure.
Figure 3 shows a piping diagram of a bag cleaning apparatus according to one embodiment of the present disclosure.
Figure 4 shows a flow diagram of a bag cleaning method according to one embodiment of the present disclosure.
Figure 5 shows a flow diagram of a bag cleaning method according to one embodiment of the present disclosure.
Figure 6 shows a schematic view of a bag handling system according to one embodiment of the present disclosure.
Detailed Description
The present disclosure will be described in further detail with reference to the drawings and embodiments. It is to be understood that the specific embodiments described herein are for purposes of illustration only and are not to be construed as limitations of the present disclosure. It should be further noted that, for the convenience of description, only the portions relevant to the present disclosure are shown in the drawings.
It should be noted that the embodiments and features of the embodiments in the present disclosure may be combined with each other without conflict. Technical solutions of the present disclosure will be described in detail below with reference to the accompanying drawings in conjunction with embodiments.
Unless otherwise indicated, the illustrated exemplary embodiments/examples are to be understood as providing exemplary features of various details of some ways in which the technical concepts of the present disclosure may be practiced. Accordingly, unless otherwise indicated, features of the various embodiments may be additionally combined, separated, interchanged, and/or rearranged without departing from the technical concept of the present disclosure.
The use of cross-hatching and/or shading in the drawings is generally used to clarify the boundaries between adjacent components. As such, unless otherwise noted, the presence or absence of cross-hatching or shading does not convey or indicate any preference or requirement for a particular material, material property, size, proportion, commonality between the illustrated components and/or any other characteristic, attribute, property, etc., of a component. Further, in the drawings, the size and relative sizes of components may be exaggerated for clarity and/or descriptive purposes. While example embodiments may be practiced differently, the specific process sequence may be performed in a different order than that described. For example, two processes described consecutively may be performed substantially simultaneously or in reverse order to that described. In addition, like reference numerals denote like parts.
When an element is referred to as being "on" or "on," "connected to" or "coupled to" another element, it can be directly on, connected or coupled to the other element or intervening elements may be present. However, when an element is referred to as being "directly on," "directly connected to" or "directly coupled to" another element, there are no intervening elements present. For purposes of this disclosure, the term "connected" may refer to physically, electrically, etc., and may or may not have intermediate components.
For descriptive purposes, the present disclosure may use spatially relative terms such as "below … …," below … …, "" below … …, "" below, "" above … …, "" above, "" … …, "" higher, "and" side (e.g., as in "sidewall") to describe one component's relationship to another (other) component as illustrated in the figures. Spatially relative terms are intended to encompass different orientations of the device in use, operation, and/or manufacture in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "below" or "beneath" other elements or features would then be oriented "above" the other elements or features. Thus, the exemplary term "below … …" can encompass both an orientation of "above" and "below". Further, the devices may be otherwise positioned (e.g., rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.
The terminology used herein is for the purpose of describing particular embodiments and is not intended to be limiting. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. Furthermore, when the terms "comprises" and/or "comprising" and variations thereof are used in this specification, the presence of stated features, integers, steps, operations, elements, components and/or groups thereof are stated but does not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components and/or groups thereof. It is also noted that, as used herein, the terms "substantially," "about," and other similar terms are used as approximate terms and not as degree terms, and as such, are used to interpret inherent deviations in measured values, calculated values, and/or provided values that would be recognized by one of ordinary skill in the art.
According to one embodiment of the present disclosure, a bag cleaning apparatus is provided.
Figure 1 illustrates a pouch cleaning apparatus 10 according to one embodiment of the present disclosure. The bag 20 may contain blood and/or blood derivatives in a frozen state, for example, blood and/or blood derivatives such as whole blood or blood plasma in a frozen state.
As shown in fig. 1, the pouch cleaning apparatus 10 may include a first part 100, a second part 200, and a third part 300 divided into three parts.
A first flushing device 110, a second flushing device 210, a second gas supply device 220 and a conveying device 400.
A first flushing device 110 may be provided at the location of the first part 100. A second flushing means 210 and a second gas supply means 220 may be provided at the location of the second part 200.
The first rinsing device 110 is used to supply a first type of rinsing liquid for rinsing the surface of the bag body 20.
The second rinsing device 210 is used to supply a second type of rinsing liquid for rinsing the surface of the bag body 20.
The second gas supply device 220 is used to supply gas to the surface of the bag body 20 washed by the second washing device 210 so as to remove the liquid from the surface of the bag body 20. For example, clean compressed gas can be supplied so that the liquid remaining on the surface of the bag is blown off.
The first type of flushing liquid and the second type of flushing liquid may both be water, both of which may be different types of water, wherein the second type of flushing liquid has a higher hygiene standard or pharmacopoeia standard (including without limitation resistivity level and/or organic content and/or microbial limit and/or heat source substance) than the first type of flushing liquid. The surface of the bag body after being flushed with the second type of flushing liquid has a microbial load that is less than the microbial load of the surface of the bag body after being flushed with the first type of flushing liquid, the first type of flushing liquid and the second type of flushing liquid being different types of water.
In the present disclosure, the rinsing liquid does not use alcohol, thereby avoiding the special requirements of EHS, but achieves the intended effect by using different types of water, such as tap water, purified water, water for injection, and the like.
The transfer device 400 is used to transfer the bag bodies 20 from the first flushing device 110 to the second gas supply device 220. The conveyor 400 may be in the form of a conveyor belt, and the pouches 20 enter at the entrance of the pouch cleaning apparatus 10 and are conveyed by the conveyor belt.
The blocking members 410 may be spaced apart from each other on the feeding device 400, so that when the pouches 20 are conveyed by the feeding device 400, the blocking members 410 are positioned behind the pouches 20 to support the pouches 20 and prevent the pouches 20 from sliding backwards. And the feeding device 400 has a certain width so that a plurality of rows (row direction parallel to the feeding direction) of the bag bodies 20 can be fed by the feeding device 400.
The first washing device 110 includes a first upper washing device 111 and a first lower washing device 112, and the first upper washing device 111 and the first lower washing device 112 are used to wash at least the upper surface and the lower surface of the bag body 20, respectively.
The first upper washing device 111 may be disposed above the conveyor 400 and wash the upper side surface of the bag body 20, the first lower washing device 112 may be disposed below the conveyor 400 and wash the lower side surface of the bag body 20, and a space through which the washing liquid passes may be provided on the conveyor 400 so as to enable the washing liquid to wash the lower side surface of the bag body 20.
The first upper side washing device 111 may include a plurality of rows of washing portions arranged along the transfer direction of the bag bodies, so that the surface of each bag body can be washed a plurality of times by the plurality of rows of washing portions. In addition, each flushing part may extend in the width direction of the conveying device 400, and a plurality of water outlets may be opened in the width direction. Can wash on conveyor 400's width direction like this, perhaps can set up a row of delivery port on width direction to wash the bag body in whole width, when having a plurality of bags bodies in this width direction distributes, can all wash every bag body.
The first lower wash means 112 may adopt the same arrangement as the first upper wash means 111. For the sake of brevity, no further description is provided herein.
For example, as shown in fig. 1, each of the first upper side washing devices 111 and the first lower side washing devices 112 may be provided with six rows.
The bag body cleaning apparatus 10 of the present disclosure may further include a first gas supply device 120, and the first gas supply device 120 is configured to supply gas to the surface of the bag body 20 rinsed by the first rinsing device 110 so as to remove the liquid from the surface of the bag body. For example, clean compressed gas can be supplied so that the liquid remaining on the surface of the bag is blown off. Wherein the first gas supplying device 120 may include a first upper gas supplying device 121 and a first lower gas supplying device 122. Wherein the first upper gas supply device 121 may be disposed at an upper side of the conveyor 400, and the first lower gas supply device 122 may be disposed at a lower side of the conveyor 400.
The first upper gas supply device 121 and the first lower gas supply device 122 may be disposed along the width direction of the conveyor 400, and a row (the row direction is a direction perpendicular to the paper surface) of gas outlets may be disposed in the width direction so as to simultaneously remove the liquid from the plurality of bag bodies distributed in the width direction of the conveyor 400.
The first gas supply device 120 may be disposed downstream in the conveying direction of the bag bodies with respect to the first flushing device 110. In addition, a second flushing device 210 is arranged downstream of the first gas supply device 120, and a second gas supply device 220 is located downstream of the second flushing device 210.
The second washing device 210 includes a second upper side washing device 211 and a second lower side washing device 212, and the second upper side washing device 211 and the second lower side washing device 212 are used for washing at least the upper side surface and the lower side surface of the bag body 20, respectively.
The second upper side washing device 211 may include a plurality of rows of washing portions arranged along the transfer direction of the bag bodies, so that the surface of each bag body can be washed a plurality of times by the plurality of rows of washing portions. In addition, each flushing part may extend in the width direction of the conveying device 400, and a plurality of water outlets may be opened in the width direction. Can wash on conveyor 400's width direction like this, perhaps can set up a row of delivery port on width direction to wash the bag body in whole width, when having a plurality of bags bodies in this width direction distributes, can all wash every bag body.
The second lower flushing device 212 may adopt the same arrangement as the second upper flushing device 211. For the sake of brevity, no further description is provided herein.
For example, as shown in fig. 1, the second upper side rinsing device 211 and the second lower side rinsing device 212 may be provided in two rows (two right rows).
The second gas supply device 220 is used for supplying gas to the surface of the bag body 20 washed by the first washing device 110 so as to remove the liquid on the surface of the bag body. For example, clean compressed gas can be supplied so that the liquid remaining on the surface of the bag is blown off. Wherein the second gas supply device 220 may include a second upper gas supply device 221 and a second lower gas supply device 222. Wherein the second upper gas supply 221 may be disposed at an upper side of the conveyor 400 and the second lower gas supply 222 may be disposed at a lower side of the conveyor 400.
The second upper gas supply unit 221 and the second lower gas supply unit 222 may be disposed along the width direction of the conveyor 400, and a row (the row direction is a direction perpendicular to the paper) of gas outlets may be disposed in the width direction so as to simultaneously remove the liquid from the plurality of bag bodies distributed in the width direction of the conveyor 400. For example, a plurality of rows of second gas supply means 220 may be provided, and two rows of second gas supply means 220 (two rows toward the left) are shown in FIG. 1
According to an example of the present disclosure, as shown in fig. 2, the pouch body cleaning apparatus 10 may further include a chamber housing, wherein the first rinsing device 110 and/or the first gas supply device 120 are accommodated in the first cleaning chamber 510, and the second rinsing device 210 and the second gas supply device 220 are accommodated in the second cleaning chamber 520. The first cleaning chamber 510 and the second cleaning chamber 520 form a space in a position where the transfer device 400 passes, so as to allow the transfer device 400 to transfer the bag body 20 from the first cleaning chamber 510 to the second cleaning chamber 520. The first washing device 110 and the second washing device 210 can be physically separated by the arrangement of the first washing chamber 510 and the second washing chamber 520, so as to avoid mutual contamination between the two. As shown in fig. 2, the bag 20 can be fed from the inlet 600 of the bag cleaning apparatus 10 onto the feeding device 400 of the bag cleaning apparatus 10 by the feeding device 400.
As shown in fig. 1, the height of the bag body 20 washed by the second washing device 210 is higher than or equal to the height of the bag body 20 washed by the first washing device 110. In the present disclosure, it is preferable that the height at which the bag body 20 is washed by the second washing device 210 is higher than the height at which the bag body 20 is washed by the first washing device 110. For example, the height of the delivery device 400 at the second flushing device 210 can be set higher than the height at the first flushing device 110. For example, the delivery device 400 may be arranged in such a way that it rises from the first flushing device 110 towards the second flushing device 210.
According to an embodiment of the present disclosure, the bag cleaning apparatus 10 further comprises a third rinsing device 310, the third rinsing device 310 is disposed between the first rinsing device 110 and the second rinsing device 210, and the third rinsing device 310 is used for supplying a third type of rinsing liquid for rinsing the surface of the bag 20. Wherein the conveying device 400 conveys the bag bodies 20 from the first rinsing device 110 to the third rinsing device 310 and the second rinsing device 210 in sequence, and the microbial load on the surfaces of the bag bodies rinsed with the third type of rinsing liquid is less than or equal to the microbial load on the surfaces of the bag bodies rinsed with the first type of rinsing liquid and is equal to or greater than the microbial load on the surfaces of the bag bodies rinsed with the second type of rinsing liquid.
The third rinsing device 310 includes a third upper rinsing device 311 and a third lower rinsing device 312, and the third upper rinsing device 311 and the third lower rinsing device 312 are respectively used for rinsing at least the upper surface and the lower surface of the bag body 20.
The third upper washing device 311 may include a plurality of rows of washing portions arranged along the conveying direction of the bag bodies, so that the surface of each bag body can be washed a plurality of times by the plurality of rows of washing portions. In addition, each flushing part may extend in the width direction of the conveying device 400, and a plurality of water outlets may be opened in the width direction. Can wash like this on conveyor 400's width direction, perhaps can set up a row of delivery port in width direction to wash the bag body in whole width, when distributing on this width direction has a plurality of bag bodies, can all wash every bag body.
The third lower flushing device 312 may take the same arrangement as the third upper flushing device 311. For the sake of brevity, no further description is provided herein.
For example, as shown in fig. 1, the third upper side flusher 311 and the third lower side flusher 312 can each be provided in two rows (two right rows).
The bag body cleaning apparatus 10 of the present disclosure may further include a third gas supply device 320, the third gas supply device 320 being configured to supply gas to the surface of the bag body 20 rinsed by the third rinsing device 310 so as to remove the liquid from the surface of the bag body 20.
The third gas supply device 320 can, for example, supply clean compressed gas so that the liquid remaining on the surface of the bag is blown off. Wherein the third gas supply device 320 may include a third upper gas supply device 321 and a third lower gas supply device 322. Wherein the third upper gas supply device 321 may be disposed at an upper side of the conveyor 400 and the third lower gas supply device 322 may be disposed at a lower side of the conveyor 400.
The third upper gas supply device 321 and the third lower gas supply device 322 may be disposed along the width direction of the conveyor 400, and a row (the row direction is a direction perpendicular to the paper surface) of gas outlets may be disposed in the width direction so as to simultaneously remove the liquid from the plurality of bag bodies distributed in the width direction of the conveyor 400. The third gas supply means 320 may be provided with a plurality of rows, for example, two rows (two rows to the left) are shown in fig. 1.
The cleanliness of the gas provided by the second gas supply device 220 may be higher than that of the gas provided by the third gas supply device 320. In addition, the cleanliness of the gas provided by the third gas supply device 320 may be higher than that of the gas provided by the first gas supply device 120.
According to an example of the present disclosure, as shown in fig. 2, the bag body cleaning apparatus 10 may further include a third cleaning chamber 530 forming a space with the first cleaning chamber 510 and the second cleaning chamber 520, respectively, in a position where the transfer device 400 passes, so as to allow the transfer device 400 to transfer the bag body 20 from the first cleaning chamber 510 to the third cleaning chamber 530 and then to the second cleaning chamber 520. The first washing chamber 510, the second washing chamber 520 and the third washing chamber 530 are arranged to physically isolate the first washing device 110, the second washing device 210 and the third washing device 310, thereby preventing mutual contamination.
The pouches 20 washed by the third washing device 310 are at a height higher than or equal to the height of the pouches washed by the first washing device 110 and lower than or equal to the height of the pouches washed by the second washing device 210. In the present disclosure, it is preferable that the bag body 20 washed by the third washing device 310 is located at a height higher than that of the bag body 20 washed by the first washing device 110 and lower than that of the bag body 20 washed by the second washing device 210. For example, the conveyor 400 may be located at a higher level at the second flushing device 210 than at the third flushing device 310, and at the third flushing device 310 than at the first flushing device 110. For example, the delivery device 400 can be arranged in such a way that it rises from the first flushing device 110 via the third flushing device 310 towards the second flushing device 210.
In the present disclosure, the purity of the second type of flushing liquid may be higher than the purity of the third type of flushing liquid, which may be higher than the purity of the first type of flushing liquid by hygienic or pharmacopoeial standards (including without limitation resistivity levels and/or organic content and/or microbiological limits and/or heat source substances). The microbial limit of the second type of flushing liquid may be lower than the microbial limit of the third type of flushing liquid, which may be lower than the microbial limit of the first type of flushing liquid, in the present disclosure, preferably the first type of flushing liquid may be circulating water, the third type of flushing liquid may be purified water, and the second type of flushing liquid may be water for injection.
Further, a piping diagram according to one embodiment of the present disclosure is shown in fig. 3. As shown in fig. 3, the first flushing device 110, the second flushing device 120, and the third flushing device 130 may be long tubular structures, and the tubular structures extend in the width direction of the conveying device 400. Further, the second gas supply device 220 and the third gas supply device 320 may also adopt a long tubular structure, and the tubular structure extends in the width direction of the conveying device 400. Wherein the upper and lower portions of each device may be symmetrically disposed.
In the present disclosure, the flushing by the bag cleaning apparatus 10 can pre-separate the blood or derivatives in a frozen state from the bag for subsequent processing (bag breaking processing of a bag breaker). In the present disclosure, therefore, the temperature of the flushing liquid provided by the flushing device may be regulated, for example the temperature of the first type of flushing liquid provided by the first flushing device 110 and/or the temperature of the second type of flushing liquid provided by the second flushing device 210 is controlled such that the bag body 20 is pre-separated from the blood and/or blood-derivatives in a frozen state contained in the bag body 20.
For example, the water temperature control devices of the first and second flushing devices 110 and 210 may be provided on the pipes of the pipeline 700 as shown in fig. 3, thereby performing temperature control on water flowing through the pipes.
In addition, the pressure of the flushing liquid provided by the flushing device may also be controlled, for example the pressure of the first type of flushing liquid provided by the first flushing device 110 and/or the pressure of the second type of flushing liquid provided by the second flushing device 210 may be adjusted based on the delivery speed of the delivery device. In addition, the pressure of the flushing liquid of the third flushing device 310 can also be controlled. The pressure control can control the flushing force of the flushing liquid to the surface of the bag body.
Further, the pressure of the compressed gas supplied from each gas supply device may be controlled.
Further, the flushing surface of the flushing liquid provided by the flushing device may be in the shape of a sector, which coincides with the conveying direction of the conveying device 400, so that a larger area of the surface of the bag body can be flushed along the conveying direction. The ejection face of the compressed gas supplied by the gas supply device may also be of the same fan shape.
According to a further embodiment of the disclosure, the second type of rinsing liquid after rinsing the bag body is collected to be used as the first type of rinsing liquid provided by the first rinsing device. For example, since the bottom surfaces of the lower sides of the first flushing device and the second flushing device serve as channels for collecting the liquid, the liquid can also be collected by means of collecting lines arranged on the bottom surfaces. Likewise, the third type of rinsing liquid after rinsing the bag body is collected to be used as the first type of rinsing liquid provided by the first rinsing device. For example, the second flushing device may be located at a higher level than the third flushing device and the third flushing device may be located at a higher level than the first flushing device, so that if liquid is recovered through the bottom surface, liquid can flow from the bottom surfaces of the second and third flushing devices into the bottom surface of the first flushing device by gravity.
The second and third types of flushing liquids may be recovered and then treated, e.g., filtered, etc., to be used as the first type of flushing liquid, which may solve the problems of water treatment and drainage after the second and third flushing devices are used.
According to one embodiment of the present disclosure, a bag cleaning method is also provided. It should be noted that the above references are made in the following description of the method, for example, the method performed by the above bag cleaning apparatus. For the sake of brevity, the description of the method omits parts of the content, and the omitted content refers to the above description.
Fig. 4 shows a flow diagram of a bag cleaning method S100 according to one embodiment of the present disclosure.
As shown in fig. 4, the bag cleaning method S100 may include the following steps:
in step S102, the surface of the bag body may be rinsed by the first type of rinsing liquid.
After the rinsing by the first type of rinsing liquid is completed, in step S104, the bag body is conveyed so as to be rinsed again. In step S106, the surface of the bag body is rinsed by the second type rinsing liquid. In step S108, after the surface of the bag body is rinsed by the second type of rinsing liquid, the liquid on the surface of the bag body is removed.
Wherein the microbial load on the surface of the bag body after being flushed with the second type of flushing liquid is less than the microbial load on the surface of the bag body after being flushed with the first type of flushing liquid, the first type of flushing liquid and the second type of flushing liquid being different types of water.
According to a further embodiment, the method further comprises: after the surface of the bag body is rinsed by the first type of rinsing liquid, the liquid on the surface of the bag body is removed.
The height at which the pouches rinsed with the second type of rinsing liquid are situated is higher or equal to the height at which the pouches rinsed with the first type of rinsing liquid are situated.
According to a further embodiment, the method further comprises: after the surface of the bag body is flushed with the first type of flushing liquid and before the surface of the bag body is flushed with the second type of flushing liquid, the surface of the bag body is flushed with a third type of flushing liquid, wherein the bag body is conveyed to be flushed sequentially with the first type of flushing liquid, the third type of flushing liquid, and the second type of flushing liquid, and the surface of the bag body after being flushed with the third type of flushing liquid has a microorganism loading that is less than the microorganism loading of the surface of the bag body after being flushed with the first type of flushing liquid and is greater than the microorganism loading of the surface of the bag body after being flushed with the second type of flushing liquid.
According to a further embodiment, the method further comprises: after the surface of the bag body is rinsed by the third type of rinsing liquid, the liquid on the surface of the bag body is removed.
According to a further embodiment, the method further comprises: before the surface of the bag is rinsed by the first type of rinsing liquid, adjusting the temperature of the first type of rinsing liquid so as to pre-melt the blood and/or blood-derivatives contained in the bag in a frozen state by the rinsing of the first type of rinsing liquid; and/or adjusting the temperature of the second type of flushing liquid so as to pre-melt the blood and/or blood-derivative contained in the bag in a frozen state by the flushing of the first type of flushing liquid, before the surface of the bag is flushed by the second type of flushing liquid.
According to a further embodiment, the method further comprises: adjusting a rinsing force of the first type of rinsing liquid on the surface of the bag body based on the conveying speed of the bag body before the surface of the bag body is rinsed by the first type of rinsing liquid; and/or adjusting the level of flushing of the second type of flushing liquid against the surface of the bag bodies based on the speed of conveyance of the bag bodies prior to flushing of the surface of the bag bodies with the second type of flushing liquid.
According to a further embodiment, the method further comprises: the method further includes adjusting a rinsing force of the third type of rinsing liquid on the surface of the bag body based on the conveying speed of the bag body before the surface of the bag body is rinsed by the third type of rinsing liquid.
According to a further embodiment, the method further comprises: the second type of rinsing liquid after rinsing the bag body is treated to be used as the first type of rinsing liquid.
According to a further embodiment, the method further comprises: the third type of rinsing liquid after rinsing the bag body is treated to be used as the first type of rinsing liquid.
Fig. 5 shows a flow chart of a bag cleaning method S200 according to a preferred embodiment of the present disclosure.
As shown in fig. 5, the method S200 may include the following steps:
in step S202, the surface of the bag body may be rinsed by the first type of rinsing liquid.
In step S204, the surface of the bag body may be rinsed by the third type of rinsing liquid.
In step S206, the liquid on the surface of the bag body is removed. The liquid at the surface may be removed, for example, by supplying a third type of compressed gas.
In step S208, the surface of the bag body may be rinsed by the second type of rinsing liquid.
In step S210, the liquid on the surface of the bag body is removed. The liquid at the surface may be removed, for example, by providing a second type of compressed gas.
As described with reference to the apparatus content, the first type of flushing liquid may be circulating water, the third type of flushing liquid may be purified water, and the second type of flushing liquid may be water for injection.
There is also provided, in accordance with an embodiment of the present disclosure, a bag handling system, as shown in fig. 6, which may include: bag body cleaning apparatus 10, bag breaking apparatus 30 and transfer apparatus 400 (not shown, see also fig. 1).
The bag cleaning device 10 may be the above-described bag cleaning device, and will not be described herein again.
The bag breaking device 30 receives the bag body after the bag body cleaning device 10 cleans, and breaks (e.g., cuts) the cleaned bag body, and separates the blood and/or blood derivatives contained in the bag body from the bag body.
The transfer device 400 is used to transfer the bag bodies in the bag body cleaning apparatus 10 and from the bag body cleaning apparatus to the bag breaking apparatus. When the bag cleaned by the bag cleaning device 10 is transferred to the bag breaking device 30, the bag may be transferred from the bag cleaning device 10 to the bag breaking device 30 by a conveyor such as the conveyor 400 used in the bag cleaning device 10, or may be transferred from the bag cleaning device 10 to the bag breaking device 30 in the form of a chute.
According to a further embodiment of the present disclosure, the bag processing system may further comprise a storage device for storing the blood and/or blood-derived product received from the bag breaking device. For example, the storage device may be in the form of a reservoir for storing blood and/or blood-derived products.
According to a further embodiment of the present disclosure, the bag handling system may further comprise transfer means for transferring the bags containing the blood and/or blood derivatives in a frozen state to the conveying means, so as to clean the bags by the bag cleaning apparatus. In addition, the transfer device can be in the form of a robot arm, and the robot arm can grip the bag filled with the blood and/or blood derivatives in a frozen state, which is conveyed by the external conveying device.
In addition, in order to improve the gripping efficiency of the robot arm, the conveying apparatus may be arranged to convey the bag bodies from the outside in a direction perpendicular to the conveying direction of the conveyor 400 in the entrance.
The transport apparatus transports the pouches in a direction from one side of the robot arm to the other, which transfers the pouches to the conveyor 400 in such a way that they are gripped alternately on one side and on the other.
According to this disclosed bag body processing system can improve treatment effeciency effectively to can make the bag body after the processing accord with GMP standard or other clean standards, and avoided the use of flammable liquid such as alcohol.
In the description herein, reference to the description of the terms "one embodiment/mode," "some embodiments/modes," "example," "specific example," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment/mode or example is included in at least one embodiment/mode or example of the application. In this specification, the schematic representations of the terms used above are not necessarily intended to be the same embodiment/mode or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments/modes or examples. Furthermore, the various embodiments/aspects or examples and features of the various embodiments/aspects or examples described in this specification can be combined and combined by one skilled in the art without conflicting therewith.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present application, "plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.
It will be understood by those skilled in the art that the foregoing embodiments are merely for clarity of illustration of the disclosure and are not intended to limit the scope of the disclosure. Other variations or modifications may occur to those skilled in the art, based on the foregoing disclosure, and are still within the scope of the present disclosure.
Claims (22)
1. A bag cleaning apparatus, the bag containing blood and/or blood derivatives in a frozen state, comprising:
a first rinsing device for supplying a first type of rinsing liquid for rinsing a surface of the bag body;
a second rinsing device for supplying a second type of rinsing liquid for rinsing the surface of the bag body;
a second gas supply device for supplying gas to the surface of the bag body after the second flushing device flushes so as to remove the liquid from the surface of the bag body; and
a conveying device for conveying the bag bodies from the first flushing device to the second gas supply device,
wherein a microbial load of the surface of the bag body after being flushed with the second type of flushing liquid is less than a microbial load of the surface of the bag body after being flushed with the first type of flushing liquid.
2. The bag cleaning apparatus according to claim 1, further comprising a first gas supply device for supplying gas to the surface of the bag after the first rinsing device rinses the surface of the bag so as to remove the liquid from the surface of the bag.
3. The bag cleaning apparatus according to claim 2, wherein said first rinsing device comprises a first upper rinsing device and a first lower rinsing device for rinsing at least an upper surface and a lower surface of said bag, respectively.
4. The bag cleaning apparatus according to claim 2, wherein the first flushing device and the first gas supplying device are housed in a first cleaning chamber.
5. The bag cleaning apparatus according to claim 1, wherein said second rinsing device comprises a second upper rinsing device and a second lower rinsing device for rinsing at least an upper surface and a lower surface of said bag, respectively.
6. The bag cleaning apparatus according to claim 1, wherein said second flushing means and said second gas supply means are housed in a second cleaning chamber.
7. The bag cleaning apparatus according to claim 1, wherein the height at which the bags are washed by the second washing device is higher than or equal to the height at which the bags are washed by the first washing device.
8. The bag cleaning apparatus according to claim 1, further comprising a third rinsing device disposed between the first rinsing device and the second rinsing device and adapted to supply a third type of rinsing liquid for rinsing the surface of the bags,
wherein the conveying device conveys the bag bodies from the first rinsing device to the third rinsing device and the second rinsing device in sequence, and the microbial load on the surface of the bag bodies rinsed with the third type of rinsing liquid is less than or equal to the microbial load on the surface of the bag bodies rinsed with the first type of rinsing liquid and is equal to or greater than the microbial load on the surface of the bag bodies rinsed with the second type of rinsing liquid.
9. The bag cleaning apparatus according to claim 8, further comprising a third gas supply device for supplying a gas to the surface of the bag after the third rinsing device rinses the surface of the bag so as to remove the liquid from the surface of the bag.
10. The bag cleaning apparatus according to claim 9, wherein the cleanliness of the gas supplied from said second gas supplying means is higher than the cleanliness of the gas supplied from said third gas supplying means.
11. The bag cleaning apparatus according to claim 9, wherein said third rinsing device comprises a third upper rinsing device and a third lower rinsing device for rinsing at least the upper surface and the lower surface of the bag, respectively.
12. The bag cleaning apparatus according to claim 9, wherein said third flushing device and said third gas supply device are housed in a third cleaning chamber.
13. The bag cleaning apparatus according to claim 9, wherein the height at which the bags are washed by the third washing device is higher than or equal to the height at which the bags are washed by the first washing device and lower than or equal to the height at which the bags are washed by the second washing device.
14. Bag cleaning apparatus according to any one of claims 1 to 13, characterized in that the temperature of the first type of flushing liquid supplied by the first flushing device and/or the temperature of the second type of flushing liquid supplied by the second flushing device is controlled so as to pre-separate the bag from the blood and/or blood derivatives contained in the bag in a frozen state.
15. Bag cleaning apparatus according to claim 14, characterized in that the pressure of the first type of rinsing liquid provided by the first rinsing device and/or the pressure of the second type of rinsing liquid provided by the second rinsing device can be adjusted on the basis of the conveying speed of the conveying device.
16. The bag cleaning apparatus according to any one of claims 1 to 15, wherein the second type of rinsing liquid after the bag is rinsed is collected to be used as the first type of rinsing liquid supplied by the first rinsing device.
17. The bag cleaning apparatus according to any one of claims 8 to 16, wherein the third type of rinsing liquid after the bag is rinsed is collected to be used as the first type of rinsing liquid provided by the first rinsing device.
18. A bag handling system, comprising:
the bag cleaning apparatus according to any one of claims 1 to 17, for cleaning a surface of the bag;
a bag breaking device for breaking the cleaned bag body and separating the blood and/or blood derivatives contained in the bag body from the bag body; and
a transfer device for transferring the bag bodies in the bag body cleaning apparatus and from the bag body cleaning apparatus to the bag breaking apparatus.
19. The processing system according to claim 18, further comprising a storage device for storing the blood and/or blood-derived product received from the bag breaking apparatus.
20. The processing system according to claim 18, further comprising transfer means for transferring the pouches containing the blood and/or blood-derivatives in a frozen state to the conveying means, so as to clean the pouches by means of the pouch cleaning apparatus.
21. The processing system according to claim 20, further comprising a conveying device for conveying the bags containing the blood and/or blood-derivatives in a frozen state, and wherein the transfer device is a robotic arm that grabs the bags from the conveying device.
22. The processing system of claim 21, wherein said transport apparatus transports said pouches in a direction from one side of said robot arm to the other, said robot arm transferring said pouches to said conveyor in alternating grasping on said one side and said other side.
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| CN202121520721.7U CN217070058U (en) | 2021-07-05 | 2021-07-05 | Bag cleaning equipment and bag processing system |
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| CN202121520721.7U CN217070058U (en) | 2021-07-05 | 2021-07-05 | Bag cleaning equipment and bag processing system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115569947A (en) * | 2021-07-05 | 2023-01-06 | 四川远大蜀阳药业有限责任公司 | Bag cleaning apparatus, bag cleaning method, and bag processing system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115569947A (en) * | 2021-07-05 | 2023-01-06 | 四川远大蜀阳药业有限责任公司 | Bag cleaning apparatus, bag cleaning method, and bag processing system |
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