CN217012233U - Novel metabolic cage with highly separated metabolic products - Google Patents

Abstract

The utility model discloses a novel metabolism cage with highly separated metabolites, and belongs to the technical field of metabolism cages. The problem of current metabolism cage complex operation and metabolite separation not thorough is solved, adopt lower floor's mosaic structure, change and dismantle the washing, the lower floor is equipped with the door plant, can directly take out urine just separator and collection system, the clearance experimental apparatus of being more convenient for, reduce the frequent dismouting to equipment such as metabolism cage support body upper portion sensor, the life of extension instrument and equipment, adopt the thickness secondary to divide the sieve simultaneously, more meticulous separation excrement and urine, the purity of experimental sample is guaranteed to the at utmost, and the sample collection mode is simple high-efficient more, the unified collection of board is dialled to the excrement and urine accessible, the urine adopts direct centrifuging tube to collect, avoid losing by the sample size that shifts repeatedly and lead to.

Description

Novel metabolic cage with highly separated metabolic products

Technical Field

The utility model relates to a novel metabolism cage with highly separated metabolites, and belongs to the technical field of metabolism cages.

Background

In the experimentation, current metabolism cage can not thoroughly separate experimental animals's urine just, and the condition that excrement and urine fell into urine collection device along the separation wall roll often appears, leads to the sample to pollute, influences the experimental result, especially when experiment sample volume is limited, has the sample volume to lose from urine just collection device transfer to measuring test tube in-process, and is very big to the influence of experimental data. Simultaneously, the metabolism cage of current integral type structure is also very loaded down with trivial details at the dismantlement in-process, when clearance urine just separation or collection device at every turn, all need take out experimental animals earlier, then demolish a great deal of sensor equipment on the metabolism cage frame and go up the cage again, just can take out interior arrangement at last, and the operation is not only consuming time, and frequent dismouting arouses very easily that precision equipment is malfunctioning, brings the puzzlement for the plant maintenance.

SUMMERY OF THE UTILITY MODEL

In order to solve the defects in the prior art, the utility model provides the novel metabolism cage with the highly separated metabolites, the urine and feces separation device and the collection device can be directly taken out, the cleaning is convenient, the test efficiency is improved, the feces and urine can be more finely separated, the collection mode is simpler and more efficient, the accuracy of an experimental sample is greatly ensured, and the consumption caused by repeated transfer of the experimental sample is avoided.

The technical scheme adopted by the utility model for solving the technical problems is as follows: the utility model provides a novel metabolism cage of metabolite high separation, the lower cage barrel has been put to the cover on the metabolism cage frame, has placed the cage of going up of raising experimental animals on the lower cage barrel, can open on the lower cage barrel bottom lateral wall and be equipped with the pipe hole, can draw out the pipe of temperature regulating equipment through the pipe hole. The lower cage barrel is provided with a door plate for taking an internal device, the lower cage barrel is internally provided with a fecaluria primary separation device for separating metabolites, a feces storage device, a collection device and a metabolite collection device, the lower cage barrel is a cylindrical barrel without a sealing cover at the top end, the outer diameter of the lower cage barrel is smaller than the inner diameter of a circular hollow area arranged on the top surface of the metabolism cage frame, the outer wall of the top part of the lower cage barrel is fixedly connected with an outer snap ring which is lapped on the top surface of the metabolism cage frame, the inner wall of the top part of the lower cage barrel is fixedly connected with an inner retaining ring for bearing an upper cage, the partial side wall of the lower cage barrel between the lower part of the outer snap ring and the bottom part of the lower cage barrel is removed, the hollow area is sealed by the door plate, the door plate is a barrel door plate with the same shape as the removed side wall of the lower cage barrel, the inner diameter of the door plate is the same as the outer diameter of the lower cage barrel, the upper and the lower parts of the hollow area of the lower parts of the hollow side wall of the lower cage barrel are fixedly connected with a circle of annular track grooves, the door plate is limited by the upper and the upper annular track grooves and the lower track grooves, the device can rotate by taking the axis of a lower cage barrel as the center of a circle in an annular track groove to realize the opening and closing of a door plate, a positioning ring is fixedly connected with the inner wall of the middle part of the lower cage barrel, the outer diameter of the positioning ring is the same as that of the lower cage barrel, the door plate of the barrel simultaneously plays a role in supporting and limiting in the opening and closing process, a feces storage device is sleeved on the positioning ring and is an annular groove with a U-shaped section, an internal thread sleeve with the outer diameter smaller than the inner diameter of the positioning ring is fixedly connected with the bottom of the feces storage device, the feces storage device is connected with a collecting device below through the internal thread sleeve, the inner diameter of the feces storage device is the same as that of an internal baffle ring, a feces and urine primary separating device buckled on the inner wall of the feces storage device is arranged on the feces storage device, metabolites of the animal in the upper cage are separated through the feces and urine primary separating device, the feces fall into the annular groove of the feces storage device on the outer side of the feces storage device, the urine falls into the collecting device below, and the separated metabolites are collected in the metabolite collecting device through the collecting device, the excrement and urine primary separation device is composed of a dome-shaped metal filter screen and a ring sleeve, the outer diameter of the ring sleeve is the same as the inner diameter of the excrement storage device, a convex ring is arranged at the top of the ring sleeve and clamped on the excrement storage device through the convex ring, a chamfer is arranged at the top of the convex ring, the bottom of the chamfer extends to the bottom surface of the convex ring, a dome-shaped metal filter screen is arranged on the ring sleeve and is a hemispherical screen body, the outer wall of the bottom of the dome-shaped metal filter screen is fixedly connected with the inner wall of the top of the ring sleeve, the aperture of grid holes of the dome-shaped metal filter screen is smaller than the diameter of metabolic excrement particles of experimental animals, primary separation of metabolites is realized, the metabolic excrement of the experimental animals in an upper cage can slide into the excrement storage device along the outer wall of the dome-shaped metal filter screen and the chamfer of the convex ring, the metabolic urine can pass through the dome-shaped metal filter screen and fall into the lower part or flow into the lower collection device along the inner wall of the dome-shaped metal filter screen, the dome-shaped metal filter screen can be replaced by a nylon filter screen; the collecting devices are respectively an excrement collecting device and a urine collecting device, the two collecting devices are conical funnels with external threads formed in the tops, the conical funnels can be screwed into internal thread sleeves of the excrement storage device in a threaded mode, outlets in the bottoms of the conical funnels are cylindrical pipe bodies, internal threads are formed in the inner walls of the bottoms of the cylindrical pipe bodies, excrement and urine secondary separation nets are arranged in the urine collecting device only, the aperture sizes of filtering grid holes of the excrement and urine secondary separation nets are smaller than that of a dome-shaped metal filter net, secondary filtering is achieved, and excrement residues are prevented from being contained in urine collected below; be equipped with metabolite collection device in collection device below, metabolite collection device is centrifuging tube and test tube, but centrifuging tube screw in on the internal thread, the test tube can overlap on the cylinder body, and urine collection device is the collection instrument commonly used of this product, is used for the collection urine that lasts at its bottom screw in centrifuging tube.

The excrement storage device is provided with a quick collection device, the quick collection device is composed of an arc-shaped clamping plate and an excrement poking plate, the radian of the arc-shaped clamping plate is the same as that of the outer wall of the excrement storage device, the bottom of the arc-shaped clamping plate is provided with a clamping groove with the same radian, the arc-shaped clamping plate is buckled on the outer vertical wall of an annular groove of the excrement storage device through the clamping groove, the excrement poking plate with the same inner diameter cross section of the annular groove is arranged in the excrement storage device, the excrement poking plate is fixedly connected with the arc-shaped clamping plate, two sides of the excrement poking plate are provided with inclined planes, an excrement outlet is formed in the inner vertical wall of the annular groove of the excrement storage device, the excrement poking plate rotates along the excrement storage device by one circle through the arc-shaped clamping plate, and excrement is discharged through the excrement outlet; when collecting excrement, select excrement and urine collection system, the cover has the test tube of collecting excrement and urine in collection system bottom.

The utility model has the beneficial effects that: in order to solve the problem that the separation of current metabolism cage is not thorough and operating procedure is loaded down with trivial details, a novel metabolism cage of metabolite high separation is provided, adopt upper and lower floor's mosaic structure, it washs to change the dismantlement, the lower floor is equipped with the door plant, urine just separator and collection system can directly take out, the clearance experimental apparatus of being more convenient for, reduce the frequent dismouting to metabolism cage support body upper portion sensor equipment, the life of extension instrument equipment, adopt thickness second grade to divide the sieve simultaneously, more meticulous separation excrement and urine, the mode of collection is simple more high-efficient, the urine can directly be collected, excrement and urine also can be collected through dialling the board in unison, the accuracy of experimental sample is guaranteed to very big degree, with the pollution degree fall to minimumly, urine is collected and is directly taken the centrifuging tube and is collected, avoided repeatedly shifting the consumption that the sample brought under the minimum condition of experimental sample.

Drawings

The utility model is further described with reference to the following figures and detailed description.

FIG. 1 is a schematic structural diagram of the present invention.

FIG. 2 is a schematic view of the structure of the present invention mounted on a metabolic cage.

Fig. 3 is a schematic view of the barrel structure of the present invention.

Fig. 4 is a cross-sectional view of the cartridge structure of the present invention.

Fig. 5 is a structural sectional view of the present invention.

Fig. 6 is a schematic structural view of the stool storage of the present invention.

The reference numbers in the figures:

1. the device comprises a lower cage barrel, 2, a feces storage device, 3, a feces and urine primary separation device, 4, a collection device, 5, a metabolite collection device, 6, a metabolism cage frame, 7, an upper cage, 11, an outer clamping ring, 12, an inner retaining ring, 13, an annular track groove, 14, a positioning ring, 15, a guide pipe hole, 16, a barrel door plate, 21, an arc-shaped clamping plate, 22, a feces poking plate, 23, a feces outlet, 31, a dome-shaped metal filter screen, 32, a ring sleeve, 41 and a feces and urine secondary separation net.

Detailed Description

As shown in figures 1-6, a novel metabolic cage with highly separated metabolites, a lower cage barrel 1 is sleeved on a metabolic cage frame 6, an upper cage 7 for breeding experimental animals is placed on the lower cage barrel 1, a door plate for taking out internal devices is arranged on the lower cage barrel 1, a feces storage device 2 for separating metabolites, a feces-urine primary separation device 3, a collection device 4 and a metabolite collection device 5 are arranged in the lower cage barrel 1, the lower cage barrel 1 is a cylindrical barrel without a sealing cover at the top end, the outer diameter of the lower cage barrel 1 is smaller than the inner diameter of a circular hollow area formed on the top surface of the metabolic cage frame 6, an outer clamping ring 11 lapped on the top surface of the metabolic cage frame 6 is fixedly connected with the outer wall of the top of the lower cage barrel 1, an inner blocking ring 12 for supporting the upper cage 7 is fixedly connected with the inner wall of the top of the lower cage barrel 1, part of the side wall of the lower cage barrel 1 between the lower part of the outer clamping ring 11 and the bottom of the lower cage barrel 1 is removed, the hollow area is sealed by the door plate, the door plate is a barrel door plate 16 with the same shape as the removed side wall of the lower cage barrel 1, the inner diameter of the door plate is the same as the outer diameter of the lower cage barrel 1, a circle of annular track groove 13 is fixedly connected above and below the hollowed area of the side wall of the lower cage barrel 1, the barrel door plate 16 is limited on the upper and lower annular track grooves 13 and can rotate in the annular track groove 13 by taking the axis of the lower cage barrel 1 as the center of a circle to realize the opening and closing of the door plate, a positioning ring 14 is fixedly connected on the inner wall of the middle part of the lower cage barrel 1, the outer diameter of the positioning ring 14 is the same as the outer diameter of the lower cage barrel 1, the barrel door plate 2 plays a supporting and limiting role in the opening and closing process, a feces storage device 2 is sleeved on the positioning ring 14, the feces storage device 2 is an annular groove with a U-shaped section, an inner thread sleeve with the outer diameter smaller than the inner diameter of the positioning ring 14 is fixedly connected at the bottom of the feces storage device 2, and a collection device 4 below the feces storage device is connected through the inner thread sleeve, the inner diameter of the excrement storage device 2 is the same as the inner diameter of the inner baffle ring 12, the excrement storage device 2 is provided with a first-stage excrement-urine separation device 3 buckled on the inner wall of the excrement storage device, metabolites of animals in the upper cage 7 are separated through the first-stage excrement-urine separation device 3, excrement falls into an annular groove of the excrement storage device 2 on the outer side of the excrement storage device, urine falls into a lower collection device 4, the separated metabolites are collected in a metabolite collection device 5 through the collection device 4, the first-stage excrement-urine separation device 3 comprises a dome-shaped metal filter net 31 and a ring sleeve 32, the outer diameter of the ring sleeve 32 is the same as the inner diameter of the excrement storage device 2, the top of the ring sleeve 32 is provided with a convex ring clamped on the excrement storage device 2 through the convex ring, the top of the convex ring is provided with a chamfer, the top is arranged on the inner wall of the ring sleeve 32, the bottom of the chamfer extends to the bottom of the convex ring, the dome-shaped metal filter net 31 is arranged on the ring sleeve 32, the dome-shaped metal filter net 31 is a hemispherical cover body, the outer wall of the bottom of the metal filter screen is fixedly connected with the inner wall of the top of the ring sleeve 32, the aperture of the grid holes of the dome-shaped metal filter screen 31 is smaller than the diameter of metabolic excrement particles of an experimental animal, primary separation of metabolites is realized, metabolic excrement of the experimental animal in the upper cage 7 can slide into the excrement storage device 2 along the outer wall of the dome-shaped metal filter screen 31 and the chamfer of the convex ring, and metabolic urine can pass through the dome-shaped metal filter screen 31 and fall into the lower part or flow into the lower collection device 4 along the inner wall of the dome-shaped metal filter screen 31; the two collecting devices 4 are respectively an excrement collecting device and a urine collecting device, the two collecting devices 3 are conical funnels with external threads formed in the tops, the conical funnels can be screwed into the internal thread sleeves of the excrement storage device 2 in a threaded mode, the bottom outlets of the conical funnels are cylindrical pipe bodies, internal threads are formed in the inner walls of the bottoms of the cylindrical pipe bodies, excrement and urine secondary separation nets 41 are arranged in the urine collecting devices only, the pore sizes of filter net meshes of the excrement and urine secondary separation nets 41 are smaller than that of the dome-shaped metal filter net 31, secondary filtering is achieved, and excrement residues are prevented from being in urine collected below; be equipped with metabolite collection device 5 in collection device 4 below, metabolite collection device 5 is centrifuging tube and test tube, but centrifuging tube screw in on the internal thread, the test tube can overlap on the cylinder tube, and urine collection device is the collection instrument commonly used of this product, is used for the collection urine that lasts at its bottom screw in centrifuging tube.

Further, a quick collecting device is arranged on the excrement storage device 2 and consists of an arc-shaped clamping plate 21 and an excrement poking plate 22, the radian of the arc-shaped clamping plate 21 is the same as that of the outer wall of the excrement storage device 2, a clamping groove with the same radian is formed in the bottom of the arc-shaped clamping plate 21, the arc-shaped clamping plate 21 is buckled on the outer vertical wall of the annular groove of the excrement storage device 2 through the clamping groove, the excrement poking plate 22 which is the same as the inner diameter and the cross section of the annular groove is arranged in the excrement storage device 2, the excrement poking plate 22 is fixedly connected with the arc-shaped clamping plate 21, inclined planes are poured on two sides of the excrement poking plate 22, an excrement outlet 23 is formed in the inner vertical wall of the annular groove of the excrement storage device 2, the excrement poking plate 22 rotates along the excrement storage device 2 for one circle through the arc-shaped clamping plate 21, and excrement is discharged through the excrement outlet 23; when gathering excrement and urine, select excrement and urine collection system, have the test tube of collecting excrement and urine at collection system 4 bottom cover.

Furthermore, the dome-shaped metal filter screen 31 of the primary separating device 3 for excrement and urine can be replaced by a nylon filter screen.

Furthermore, a conduit hole can be formed in the side wall of the bottom of the lower cage cylinder body 1, and a conduit of the temperature control device can be led out through the conduit hole.

The device adopts the structure of upper and lower floor's inserted, can directly take out urine just separator and collection system through the door plant, be more convenient for clear up experimental apparatus, reduce the frequent dismouting to accurate part and metabolism cage frame upper portion sensor equipment, prolong the life of instrument equipment, adopt thickness second grade to divide the sieve simultaneously, more meticulous separation excrement and urine, the mode of collection is simple more high-efficient, the urine can directly be collected, excrement and urine also can be through dialling the unified collection of board, the accuracy of experimental sample is guaranteed to very big degree, with the pollution degree fall to minimumly, the urine is collected and is directly taken the centrifuging tube and collect, avoided shifting the consumption that the sample brought repeatedly under the minimum condition of experimental sample.

Claims (4)

1. The utility model provides a novel metabolism cage of metabolite high separation, the cover has been put down cage barrel (1) on metabolism cage frame (6), has placed last cage (7) of raising laboratory animal on lower cage barrel (1), is equipped with the door plant that is used for the interior arrangement of taking on lower cage barrel (1), its characterized in that: a feces storage device (2) used for separating metabolites, a feces and urine primary separation device (3), a collection device (4) and a metabolite collection device (5) are arranged in the lower cage barrel (1), the lower cage barrel (1) is a cylindrical barrel without a sealing cover at the top end, the outer diameter of the lower cage barrel is smaller than the inner diameter of a circular hollow area arranged on the top surface of the metabolism cage frame (6), the outer wall of the top of the lower cage barrel (1) is fixedly connected with an outer snap ring (11) lapped on the top surface of the metabolism cage frame (6), the inner wall of the top of the lower cage barrel (1) is fixedly connected with an inner blocking ring (12) used for supporting the upper cage (7), part of the side wall of the lower cage barrel (1) between the lower part of the outer snap ring (11) and the bottom of the lower cage barrel (1) is removed, the hollow area is sealed through a door panel, the door panel is a barrel door panel (16) with the same shape as the removed side wall of the lower cage barrel (1), and the inner diameter of the door panel is the same as the outer diameter of the lower cage barrel (1), the excrement storage device is characterized in that a circle of annular track groove (13) is fixedly connected above and below a hollowed-out area of the side wall of a lower cage barrel body (1), a barrel door plate (16) is limited in two upper and lower annular track grooves (13), a positioning ring (14) is fixedly connected with the inner wall of the middle part of the lower cage barrel body (1), an excrement storage device (2) is sleeved on the positioning ring (14), the excrement storage device (2) is an annular groove with a U-shaped cross section, an inner thread sleeve with an outer diameter smaller than that of the positioning ring (14) is fixedly connected to the bottom of the annular groove, the excrement storage device (2) is connected with a collecting device (4) below through the inner thread sleeve, the inner diameter of the excrement storage device (2) is the same as that of an inner retaining ring (12), an excrement and urine primary separating device (3) buckled on the inner wall of the excrement storage device (2) is arranged on the excrement storage device, and the urine primary separating device (3) is composed of a dome-shaped metal filter screen (31) and a ring sleeve (32), the outer diameter of the ring sleeve (32) is the same as the inner diameter of the excrement storage device (2), a convex ring is arranged at the top of the ring sleeve (32), the ring sleeve is clamped on the inner wall of the excrement storage device (2) through the convex ring, a chamfer is arranged at the top of the convex ring, the bottom of the chamfer extends to the bottom surface of the convex ring, a dome-shaped metal filter screen (31) is arranged on the ring sleeve (32), the dome-shaped metal filter screen (31) is a hemispherical screen body, the outer wall of the bottom of the dome-shaped metal filter screen is fixedly connected with the inner wall of the top of the ring sleeve (32), the aperture of grid holes of the dome-shaped metal filter screen (31) is smaller than the diameter of metabolic excrement particles of experimental animals, and primary separation of metabolites is realized; the excrement collecting device and the urine collecting device are respectively provided with two collecting devices (4), the two collecting devices (4) are conical funnels with external threads formed in the tops, the conical funnels can be screwed into the internal thread sleeves of the excrement storage device (2) in a threaded mode, outlets in the bottoms of the conical funnels are cylindrical tube bodies, internal threads are formed in the inner walls of the bottoms of the cylindrical tube bodies, only the excrement and urine secondary separation net (41) is arranged in the urine collecting device, and the aperture size of grid holes of a filter screen of the excrement and urine secondary separation net (41) is smaller than that of a dome-shaped metal filter screen (31), so that secondary filtration is achieved; be equipped with metabolite collection device (5) in collection device (4) below, metabolite collection device (5) are centrifuging tube and test tube, but on the internal thread of centrifuging tube screw in, the test tube can overlap on the cylinder body.

2. The novel metabolic cage with highly separated metabolites according to claim 1, wherein: be equipped with quick collection device on storing up excrement device (2), quick collection device comprises arc cardboard (21) and group dropping board (22), the radian of arc cardboard (21) is the same with storage excrement device (2) outer wall radian, the draw-in groove of same radian is seted up to arc cardboard (21) bottom, arc cardboard (21) are detained on the outer vertical wall of the annular of storing up excrement device (2) through the draw-in groove, it dials dropping board (22) rather than the annular internal diameter cross-section the same to be equipped with in storage excrement device (2), dial dropping board (22) and arc cardboard (21) fixed connection, it has the inclined plane to dial dropping board (22) both sides, seted up on the annular inner vertical wall of storing up excrement device (2) excrement mouth (23).

3. The novel metabolic cage with highly separated metabolites according to claim 1, wherein: the dome-shaped metal filter screen (31) of the primary excrement-urine separation device (3) can be replaced by a nylon filter screen.

4. The novel metabolic cage with highly separated metabolites according to claim 1, wherein: the side wall of the bottom of the lower cage cylinder body (1) can be provided with a conduit hole (15).

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