CN217007847U

CN217007847U - Slide frame and optical microscope system

Info

Publication number: CN217007847U
Application number: CN202220801545.2U
Authority: CN
Inventors: 王瑾瑜; 王文娟; 曹慧珍
Original assignee: Tsinghua University
Current assignee: Tsinghua University
Priority date: 2022-04-08
Filing date: 2022-04-08
Publication date: 2022-07-19
Anticipated expiration: 2032-04-08

Abstract

The utility model relates to a slide frame and an optical microscope system. The slide frame includes: a bearing plate and a leveling member; the bearing plate is provided with a plurality of slide accommodating cavities, and the leveling pieces are used for enabling the bearing plate to be horizontally distributed. According to the slide rack, the bearing plate is provided with the plurality of slide accommodating cavities which can bear the plurality of slides, so that a plurality of samples can be detected, an imaging experimenter does not need to manually replace the slides by one slide, the shooting time is shortened, and the operation intensity is reduced; in addition, considering that the bearing plate can simultaneously bear a plurality of slides so that the plurality of slides (especially the slides at the two ends of the outermost side) are not placed flatly, the bearing plate can be adjusted by the leveling piece of the slide rack, so that the bearing plates are horizontally distributed, and the accuracy of the optical microscope for detecting the samples on the slides is ensured.

Description

Slide frame and optical microscope system

Technical Field

The utility model relates to the technical field of optical microscopes, in particular to a slide frame and an optical microscope system.

Background

The optical microscope plays an important role in observing and detecting tiny signals of cells, pathology and the like in the biological and medical fields, and particularly, the laser scanning confocal microscope is an essential tool in biological research. Currently, specimen-bearing slides are placed on slide racks, which are then mounted on the stage of a microscope for subsequent testing. However, the conventional slide rack can only support one slide, and when a plurality of samples need to be detected, an experimenter who needs to image manually replaces the slide by a single slide, so that the shooting time is prolonged, and the operation strength is increased.

SUMMERY OF THE UTILITY MODEL

In view of the above, it is necessary to provide a slide rack and an optical microscope system for solving the technical problems of the imaging experimenter that the shooting time is prolonged and the work intensity is increased because the slide is manually replaced by a single slide.

A slide rack, comprising: a bearing plate and a leveling member;

the bearing plate is provided with a plurality of slide accommodating cavities, and the leveling pieces are used for enabling the bearing plate to be horizontally distributed.

In one embodiment, the carrier plate is provided with a light-transmitting window, and a first recessed area and a second recessed area which are adjacent to the light-transmitting window, the first recessed area and the second recessed area are distributed on two sides of the light-transmitting window along the width direction of the light-transmitting window, and the light-transmitting window, the first recessed area and the second recessed area are matched to form a plurality of slide accommodating cavities.

In one embodiment, the first recessed region and the second recessed region are respectively provided with a plurality of protrusions distributed at intervals along the length direction of the light-transmitting window, and the protrusions are used for partitioning the slide accommodating cavities.

In one embodiment, the leveling member comprises a plurality of leveling screws, which are arranged in the edge region of the carrier plate.

In one embodiment, a plurality of mounting holes are further formed in the edge area of the bearing plate, and the mounting holes and the leveling screws are distributed in a staggered manner.

In one embodiment, the slide rack further includes a plurality of clamps disposed on the carrier plate for clamping slides in corresponding slide receiving cavities.

In one embodiment, the clamp comprises: the mounting shell is arranged on the bearing plate, the elastic piece is arranged in the mounting shell, and the top bead is arranged on the elastic piece;

an opening is formed in the end, close to the corresponding slide accommodating cavity, of the mounting shell, and the elastic piece is used for providing acting force for the top bead to move towards the opening.

In one embodiment, the outer wall of the mounting shell is provided with threads, the wall of the bearing plate is provided with a fixing through hole, and the wall of the fixing through hole is provided with threads matched with the threads on the outer wall of the mounting shell.

In one embodiment, the end of the mounting shell remote from the corresponding slide receiving chamber is provided with a tool operating slot.

An optical microscope system comprising an optical microscope and a slide rack as in the previous item, the slide rack being arranged on a stage of the optical microscope.

According to the slide rack and the optical microscope system, the bearing plate is provided with the plurality of slide accommodating cavities which can bear a plurality of slides, so that a plurality of samples can be detected, imaging experimenters do not need to manually replace the slides by one slide, the shooting time is shortened, and the operation intensity is reduced; in addition, considering that the bearing plate can simultaneously bear a plurality of slides so that the plurality of slides (especially the slides at the two ends of the outermost side) are not placed flatly, the bearing plate can be adjusted by the leveling piece of the slide rack, so that the bearing plates are horizontally distributed, and the accuracy of the optical microscope for detecting the samples on the slides is ensured.

Drawings

FIG. 1 is a schematic view of a slide rack according to an embodiment of the present invention;

fig. 2 is a schematic structural diagram of a clamping member according to an embodiment of the present invention.

Wherein the reference numerals in the drawings are as follows:

100. carrying a plate; 110. a slide accommodating chamber; 120. a light transmissive window; 130. a first recessed region; 140. a second recessed region; 150. a protrusion; 160. mounting holes; 200. a leveling member; 210. leveling screws; 300. a clamping member; 310. mounting a shell; 311. a tool operating slot; 320. an elastic member; 330. and (4) carrying out top bead.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.

In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the utility model and to simplify the description, and are not intended to indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and are not to be considered limiting of the utility model.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless explicitly specified otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be interconnected within two elements or in a relationship where two elements interact with each other unless otherwise specifically limited. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

In the present invention, unless otherwise expressly stated or limited, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature "under," "beneath," and "under" a second feature may be directly under or obliquely under the second feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.

As shown in fig. 1, an embodiment of the present invention provides a slide rack comprising: a bearing plate 100 and a leveling member 200; the carrier plate 100 is provided with a plurality of slide receiving cavities 110 and leveling members 200 for horizontally distributing the carrier plate 100.

It will be appreciated that the slide receiving chamber 110 is for receiving a slide. Regarding the arrangement of the slide accommodating chambers 110, as an example, referring to fig. 1, a plurality of slide accommodating chambers 110 are arranged in sequence along the longitudinal direction of the carrier plate 100, and the longitudinal direction of each slide accommodating chamber 110 is the same as the width direction of the carrier plate 100. Wherein the number of the slide accommodating chambers 110 can be set to 2, 3, 4, etc., and the number of the slide accommodating chambers 110 can be set to 4 at most in consideration of the influence of the stage moving range of the optical microscope. The "length direction" and "width direction" referred to herein are based on those shown in fig. 1.

In the slide rack, the carrier plate 100 is provided with the plurality of slide accommodating cavities 110 capable of supporting a plurality of slides, so that a plurality of samples can be detected, an imaging experimenter does not need to manually replace the slides by one slide, the shooting time is shortened, and the operation intensity is reduced; in addition, considering that the bearing plate 100 can simultaneously support a plurality of slides, so that the plurality of slides (especially the slides at the two outermost ends) are not placed evenly, the leveling member 200 of the slide rack can adjust the bearing plate 100 to horizontally distribute the bearing plate 100, so that the plurality of slides are placed evenly, especially, the height difference of the slides at the two outermost ends can be obviously reduced, and thus, the accuracy of the optical microscope in detecting the samples on the slides is ensured.

In some embodiments of the present invention, as shown in fig. 1, the carrier plate 100 has a light-transmissive window 120, and a first recessed area 130 and a second recessed area 140 adjacent to the light-transmissive window 120, the first recessed area 130 and the second recessed area 140 are distributed on two sides of the light-transmissive window 120 along a width direction of the light-transmissive window 120, wherein the light-transmissive window 120 cooperates with the first recessed area 130 and the second recessed area 140 to form a plurality of slide accommodating cavities 110. A first recessed area 130 for overlapping one end of the slide, and a second recessed area 140 for overlapping the other end of the slide; in addition, the light-transmitting window 120 is not only used for enabling the light of the optical microscope to pass through the slide, thereby ensuring the normal detection of the sample on the slide, but also the light-transmitting window 120 reserves a position for manual operation, so that the slide lapped on the concave area can be conveniently taken down; .

Further, as shown in fig. 1, in some embodiments of the present invention, a plurality of protrusions 150 are disposed on each of the first and second recessed

regions

130, 140 at intervals along the length direction of the light-transmissive window 120, and the protrusions 150 are used to partition the slide accommodating chamber 110. The protrusion 150 divides the area where the light-transmitting window 120 cooperates with the first recessed area 130 and the second recessed area 140 into a plurality of slide accommodating cavities 110, which not only facilitates the placement of the slides, but also limits the slides along the length direction of the carrier plate 100.

Regarding the fixing manner of the protrusion 150, the protrusion 150 may be integrally formed, adhered, welded, or the like on the first and second recessed

areas

130 and 140. The number of the protrusions 150 may be limited according to the number of the slide accommodating chambers 110, for example, if the number of the slide accommodating chambers 110 is 4, 3 protrusions 150 are disposed on each of the first and second recessed

regions

130 and 140 and spaced apart from each other along the length direction of the light-transmissive window 120. The shape of the protrusion 150 may be a straight line, a wave, a bent line, or the like.

In some embodiments of the present invention, as shown in fig. 1, the leveling member 200 includes a plurality of leveling screws 210, and the leveling screws 210 are disposed at an edge region of the bearing plate 100. It can be understood that the edge region of the carrier plate 100 is provided with a plurality of screw holes for the leveling screws 210 to pass through. The length of each leveling screw 210 extending out of the bearing plate 100 can be adjusted according to the flatness of the operating platform of the optical microscope, so that the bearing plates 100 are horizontally distributed, and the accuracy of the optical microscope in detecting the sample on the slide is ensured.

As for the number of the leveling screws 210, 1, 2, 3 or more may be provided. Regarding the specific position of the leveling screws 210 on the loading plate 100, as an example, as shown in fig. 1, when the number of the leveling screws 210 is set to 3, 2 leveling screws 210 are distributed at both ends of one side in the width direction in the loading plate 100, and the other 1 leveling screw 210 is distributed at the center of the other side in the width direction in the loading plate 100.

Further, as shown in fig. 1, in some embodiments of the present invention, the edge region of the loading plate 100 is further provided with a plurality of mounting holes 160, and the mounting holes 160 are staggered with the leveling screws 210. A screw member, such as a screw, for mounting the carrier plate 100 on the operation table of the optical microscope through the corresponding mounting hole 160; in addition, the installation holes 160 and the leveling screws 210 are distributed in a staggered manner, which not only can ensure the installation firmness of the bearing plate 100 on the operating platform of the optical microscope, but also can ensure the leveling effect of the leveling screws 210 on the bearing plate 100.

As for the number of the mounting holes 160, 1, 2, 3 or more may be provided. Regarding the specific location of the mounting holes 160 on the loading plate 100, as an example, as shown in fig. 1, when the number of the mounting holes 160 is set to 3, 1 of the mounting holes 160 is distributed in the center of one side in the width direction in the loading plate 100, and the other 2 mounting holes 160 are distributed at both ends of the other side in the width direction in the loading plate 100.

As shown in fig. 1, in some embodiments of the utility model, the slide rack further includes a plurality of clamps 300 disposed on the carrier plate 100, the clamps 300 for clamping slides in corresponding slide receiving cavities 110. The clamping piece 300 can prevent the slide from shaking in the moving or detecting process, and the detection accuracy is ensured.

As for the number of the holders 300, the same as the number of slides, one holder 300 for holding one slide, for example, 4 each, may be provided.

Specifically, in some embodiments of the present invention, as shown in fig. 2, the clamp 300 includes: a mounting case 310 disposed on the loading plate 100, an elastic member 320 disposed in the mounting case 310, and a top bead 330 disposed on the elastic member 320; openings are provided in the ends of the mounting cases 310 adjacent to the corresponding slide receiving chambers 110, and the elastic members 320 are used to provide a force to the top beads 330 to move toward the openings. When a slide is mounted in the corresponding slide accommodating cavity 110, the slide presses the top bead 330 to move towards the inside of the mounting shell 310, so that the elastic member 320 is compressed and deformed, and once the experimenter to be imaged looses his hands on the slide, the elastic member 320 is reset, and the top bead 330 is provided with a force moving towards the opening, so that the slide is clamped in the corresponding slide accommodating cavity 110 by the top bead 330.

Optionally, the elastic member 320 is a spring. Such elastic members 320 are readily available and inexpensive.

Optionally, the diameter of the top bead 330 is larger than the diameter of the opening of the mounting housing 310. In this way, the top bead 330 is not separated from the mounting housing 310, and the elastic member 320 can be directly placed in the mounting housing 310 without being connected to the top bead 330 and the mounting housing 310.

Optionally, a thread is disposed on an outer wall of the mounting shell 310, a fixing hole is disposed on a wall of the bearing plate 100, and a thread adapted to the thread on the outer wall of the mounting shell 310 is disposed on the wall of the fixing hole. In this manner, the mounting of the clip 300 on the carrier plate 100 is facilitated. Of course, in other embodiments, the mounting housing 310 can be fixed in the fixing hole on the wall of the carrier plate 100 by using an adhesive.

As for the mounting position of the mounting case 310 on the loading plate 100, as an example, the mounting case 310 is disposed on a sidewall facing the second recess region 140 in the first recess region 130 of the loading plate 100, wherein the sidewall is provided with a fixing hole for mounting the mounting case 310; alternatively, referring to fig. 1, the clip 300 is provided on a sidewall of the second recess region 140 of the carrier plate 100 facing the first recess region 130, wherein the sidewall is provided with a fixing hole for mounting the mounting case 310. In addition, referring to fig. 2, the end of the mounting case 310 remote from the corresponding slide accommodating chamber 110 may be provided with a tool operating groove 311. A tool can be inserted into the tool operation groove 311 to screw the mounting case 310, thereby accomplishing the attachment and detachment of the clip 300 to the carrier plate 100.

In another aspect, an embodiment of the present invention further provides an optical microscope system, which includes an optical microscope and the slide rack described in any one of the above items, where the slide rack is disposed on an operation platform of the optical microscope.

In the optical microscope system, the plurality of slide accommodating cavities 110 are formed in the carrier plate 100 of the slide rack and can support a plurality of slides, so that a plurality of samples can be detected, the slides do not need to be replaced by single imaging experimenters manually, the shooting time is shortened, and the operation intensity is reduced; in addition, considering that the carrier plate 100 can simultaneously support a plurality of slides so that the plurality of slides (especially the slides at the two outermost ends) are not placed evenly, the leveling member 200 of the slide rack can adjust the carrier plate 100, so that the carrier plate 100 is horizontally distributed, thereby ensuring the accuracy of the optical microscope in detecting the samples on the slides.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the utility model. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. A slide rack, comprising: a bearing plate (100) and a leveling member (200);

the bearing plate (100) is provided with a plurality of slide accommodating cavities (110), and the leveling piece (200) is used for horizontally distributing the bearing plate (100).

2. The slide rack according to claim 1, wherein the carrier plate (100) has a light transmissive window (120) and a first and a second recessed area (130, 140) adjacent to the light transmissive window (120), the first and the second recessed area (130, 140) are distributed on both sides of the light transmissive window (120) along the width direction of the light transmissive window (120), and the light transmissive window (120) and the first and the second recessed area (130, 140) cooperate to form a plurality of the slide receiving cavities (110).

3. The slide rack according to claim 2, wherein the first recessed area (130) and the second recessed area (140) are each provided with a plurality of protrusions (150) spaced apart along a length of the light transmissive window (120), the protrusions (150) separating the slide receiving cavities (110).

4. Slide rack according to claim 1, wherein the levelling member (200) comprises a plurality of levelling screws (210), the levelling screws (210) being arranged at an edge region of the carrier plate (100).

5. The slide rack according to claim 4, wherein the edge area of the carrier plate (100) is further provided with a plurality of mounting holes (160), the mounting holes (160) being staggered with the leveling screws (210).

6. The slide rack according to any of claims 1-5, further comprising a plurality of clamping members (300) disposed on the carrier plate (100), the clamping members (300) being for clamping slides in corresponding slide receiving cavities (110).

7. Slide rack according to claim 6, wherein the clamping member (300) comprises: a mounting case (310) provided on the carrier plate (100), an elastic member (320) provided in the mounting case (310), and a top bead (330) provided on the elastic member (320);

an opening is arranged on the end part of the mounting shell (310) close to the corresponding slide accommodating cavity (110), and the elastic piece (320) is used for providing force for the top bead (330) to move towards the opening.

8. The slide holder according to claim 7, wherein the mounting housing (310) is provided with threads on its outer wall, the carrier plate (100) is provided with fixing holes on its wall, and the fixing holes are provided with threads on its wall that are adapted to the threads on the outer wall of the mounting housing (310).

9. The slide rack of claim 8 wherein the mounting housing (310) has a tool operating slot (311) disposed on an end thereof remote from the corresponding slide receiving cavity (110).

10. An optical microscope system comprising an optical microscope and the slide holder of any of claims 1-9 disposed on a stage of the optical microscope.