CN216946938U - Separator is used in stem cell processing - Google Patents

Separator is used in stem cell processing Download PDF

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Publication number
CN216946938U
CN216946938U CN202122865026.0U CN202122865026U CN216946938U CN 216946938 U CN216946938 U CN 216946938U CN 202122865026 U CN202122865026 U CN 202122865026U CN 216946938 U CN216946938 U CN 216946938U
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fixedly connected
test tube
rotating
stem cell
tube shell
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CN202122865026.0U
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刘璐
廉云飞
廖联明
徐静
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Jiangsu Tuohong Kangheng Pharmaceutical Co ltd
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Jiangsu Tuohong Kangheng Pharmaceutical Co ltd
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Abstract

The utility model provides a separating device for stem cell treatment, which belongs to the technical field of stem cell treatment and comprises a separating box, wherein a box cover is arranged at the top of the separating box, a connecting ring is fixedly connected to the bottom of the box cover, a supporting plate is fixedly connected to the inner side of the separating box, a motor is fixedly connected to the inner bottom wall of the separating box, a transmission shaft is fixedly connected to the output end of the motor, and the top of the transmission shaft penetrates through the supporting plate and is fixedly connected with a driving gear. The test tube separation device solves the problems of low separation efficiency, unstable fixation of test tubes and incapability of fixing test tubes of different sizes, in the test tube separation device, the threaded rod can move towards the inner side of a test tube shell by rotating the threaded rod to drive the rotary joint, the clamping plate and the clamping pad to approach the test tubes and clamp the test tubes, the stability of the test tubes in the separation and extraction process is ensured, and the test tubes of different diameters can be fixed by controlling the movement of the clamping plate 136.

Description

Separator is used in stem cell processing
The technical field is as follows:
the utility model belongs to the technical field of stem cell treatment, and particularly relates to a separating device for stem cell treatment.
Background art:
stem cells are primitive cells having self-renewal and multipotential differentiation potential, which are cells of origin of the body and can differentiate into one or more cells constituting human tissues or organs under specific conditions. Self-renewal refers to the ability of stem cells to maintain the size of stem cell populations through cell division; the multi-directional differentiation means that stem cells have plasticity and can be differentiated into different tissue cells under different environments so as to form various complex tissues and organs of an organism. Adipose-derived stem cells are recently isolated from adipose tissues as stem cells having a multi-differentiation potential, which can be differentiated into osteoblasts, chondroblasts, adipocytes, etc. under specific induction conditions.
In the process of extracting stem cells, separation and extraction are required, but the conventional separation device has low separation and extraction efficiency, is unstable in fixing test tubes, and cannot fix test tubes of different sizes, thereby providing a separation device for processing stem cells.
The utility model has the following contents:
the utility model provides a separating device for stem cell processing, and aims to solve the problems that the separating efficiency is low, the fixing of test tubes is unstable, and the test tubes with different sizes cannot be fixed.
The utility model provides a separating device for stem cell treatment, which comprises a separating box, wherein the top of the separating box is provided with a box cover, the bottom of the box cover is fixedly connected with a connecting ring, the inner side of the separating box is fixedly connected with a supporting plate, the inner bottom wall of the separation box is fixedly connected with a motor, the output end of the motor is fixedly connected with a transmission shaft, the top of transmission shaft runs through backup pad and fixedly connected with driving gear, the top of backup pad is rotated and is connected with a plurality of evenly distributed's dwang, and is a plurality of the equal fixedly connected with driven gear in the outside of dwang, it is a plurality of the top of dwang and the equal fixedly connected with rotary disk in the top of transmission shaft, it is a plurality of the equal fixedly connected with in top of rotary disk examination tube shell, it is a plurality of all be provided with fixture on the examination tube shell, the bottom fixedly connected with ultraviolet tube of case lid.
Furthermore, the outer side of the connecting ring is provided with threads, and the top of the separating box is provided with an annular groove matched with the connecting ring.
Through adopting above-mentioned technical scheme, utilize the go-between to make the case lid cover at the top of separator box, can be when carrying out the separation and draw be in a sealed environment in the separator box, reduce the interference of external environment factor to cooperation ultraviolet tube can carry out germicidal treatment to the inboard of separator box.
Furthermore, the transmission shaft is rotatably connected with the middle part of the supporting plate, and the outer side of the driving gear is meshed with the outer sides of the driven gears.
Through adopting above-mentioned technical scheme, utilize the driving gear to drive a plurality of driven gear's rotation, separate and draw the operation. The efficiency of separation extraction is improved.
Furthermore, the driven gears are uniformly distributed on the circumference by taking the driving gear as the center, and the inner bottom wall of the test tube shell is arranged in an elliptical chamfer.
Through adopting above-mentioned technical scheme, driven gear's distribution makes and does not have the interference between each test tube shell, and the bottom setting of test tube shell is favorable to placing of test tube.
Furthermore, the clamping mechanism comprises a rotating ring, a plane gear, two rotating gears, two threaded rods, two rotary joints, two clamping plates, two clamping pads and four limiting rods, wherein the rotating ring is rotatably connected with the outer side of the test tube shell, the plane gear is fixedly connected with the bottom of the rotating ring, the two rotating gears are symmetrically distributed on the left side and the right side of the test tube shell, one end of each threaded rod is fixedly connected with one side, close to the test tube shell, of each rotating gear, the two rotary joints are fixedly connected with the other ends of the two threaded rods respectively, the two clamping plates are rotatably connected with the two rotary joints respectively, the two clamping pads are fixedly connected with the outer sides of the two clamping plates respectively, and the four limiting rods are uniformly distributed on the left side and the right side of the test tube shell and are fixedly connected with the outer sides of the clamping plates respectively.
Through adopting above-mentioned technical scheme, can fix the test tube of different diameters size to it is fixed stable, guarantee the test tube and at the stability of the in-process that separates the extraction, guarantee the quality of extracting.
Furthermore, the inner side of the rotating ring is fixedly connected with an annular sliding strip, and the outer side of the test tube shell is provided with an annular sliding groove matched with the annular sliding strip.
Through adopting above-mentioned technical scheme, utilize the slip stability that the swivel becket can be guaranteed to the annular slip strip, and then can guarantee that the swivel becket stably drives the rotation of running gear when rotating.
Furthermore, the outer side of the rotating gear is meshed with the bottom of the plane gear, the threaded rod is in threaded connection with the side wall of the test tube shell, the side wall of the test tube shell is provided with a sliding hole matched with the limiting rod, the limiting rod is in sliding connection with the side wall of the test tube shell, the clamping pad is made of rubber products, and the top of the rotating ring is fixedly connected with rotating buckles which are uniformly distributed.
Through adopting above-mentioned technical scheme, threaded rod and test tube shell threaded connection can drive the removal of threaded rod when the rotating ring rotates, utilize the gag lever post to restrict the removal of threaded rod, grip block, and the centre gripping pad adopts rubber products can increase frictional force to guarantee the stability to the test tube centre gripping, rotates to detain the rotation of convenience to the rotating ring.
Compared with the prior art, the technical scheme of the utility model has the following beneficial technical effects:
1. in the utility model, through the rotating ring, the rotating gear, the threaded rod, the cooperation of grip block etc., it rotates the knot and rotates the rotating ring to rotate, the rotating ring drives the rotation of face gear, face gear drives the rotation of rotating gear, rotating gear drives the rotation of threaded rod in the rotation in-process, the threaded rod rotates and can make the threaded rod drive rotary joint to the inboard removal of test tube shell, the grip block, the centre gripping pad is close to and centre gripping test tube to the test tube, guarantee the stability of test tube in the separation extraction in-process, and can fix the test tube of different diameter sizes through the removal of control grip block.
2. According to the utility model, through the matching of the motor, the driving gear, the test tube shell, the driven gear and the like, the output end of the motor drives the transmission shaft to rotate, the transmission shaft drives the driving gear and the rotating disc positioned at the top of the driving gear to rotate, the driving gear drives the plurality of driven gears, the rotating rod and the rotating disc to rotate, so that the plurality of test tube shells synchronously rotate to act on stem cells in the test tubes, and the separation efficiency is improved by simultaneously acting on the plurality of test tubes.
Additional features and advantages of the utility model will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the utility model. The objectives and other advantages of the utility model may be realized and attained by the structure particularly pointed out in the written description and drawings.
Description of the drawings:
the accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain the principles of the utility model and not to limit the utility model. In the drawings:
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is an enlarged view of the structure at A in FIG. 1;
FIG. 3 is a schematic bottom view of the face gear of the present invention
FIG. 4 is a schematic top view of a driving gear of the present invention.
Reference numerals: 1. a separation tank; 2. a box cover; 3. a connecting ring; 4. a support plate; 5. a motor; 6. a drive shaft; 7. a driving gear; 8. rotating the rod; 9. a driven gear; 10. rotating the disc; 11. an ultraviolet lamp tube; 12. testing the tube shell; 13. a clamping mechanism; 131. a rotating ring; 132. a face gear; 133. a rotating gear; 134. a threaded rod; 135. a rotary joint; 136. a clamping plate; 137. a clamping pad; 138. a limiting rod.
The specific implementation mode is as follows:
in order to make the objects, technical solutions and advantages of the technical solutions of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the drawings of the specific embodiments of the present invention. Like reference symbols in the various drawings indicate like elements. It should be noted that the described embodiments are only some embodiments of the utility model, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the described embodiments of the utility model without inventive step, are within the scope of protection of the utility model.
As shown in fig. 1-4, the present invention provides a separation device for stem cell treatment, which includes a separation box 1, a box cover 2 is disposed on the top of the separation box 1, a connection ring 3 is fixedly connected to the bottom of the box cover 2, a support plate 4 is fixedly connected to the inner side of the separation box 1, a motor 5 is fixedly connected to the inner bottom wall of the separation box 1, a transmission shaft 6 is fixedly connected to the output end of the motor 5, the top of the transmission shaft 6 penetrates through the support plate 4 and is fixedly connected with a driving gear 7, the top of the support plate 4 is rotatably connected with a plurality of uniformly distributed rotation rods 8, the outer sides of the plurality of rotation rods 8 are fixedly connected with driven gears 9, the tops of the plurality of rotation rods 8 and the top of the transmission shaft 6 are fixedly connected with rotation disks 10, the tops of the plurality of rotation disks 10 are fixedly connected with test tube shells 12, clamping mechanisms 13 are disposed on the plurality of test tube shells 12, and ultraviolet tube 11 is fixedly connected to the bottom of the box cover 2.
The outside of go-between 3 is provided with the screw thread, and the annular groove that matches with go-between 3 is seted up at the top of separator box 1, utilizes go-between 3 to make case lid 2 cover at the top of separator box 1, can be when carrying out the separation and draw be in a sealed environment in separator box 1, reduces the interference of external environment factor to cooperation ultraviolet tube 11 can carry out germicidal treatment to the inboard of separator box 1.
The transmission shaft 6 is connected with the middle part of the supporting plate 4 in a rotating mode, the outer side of the driving gear 7 is meshed with the outer sides of the driven gears 9, and the driving gear 7 can be used for driving the driven gears 9 to rotate to perform separation and extraction operation. The efficiency of separation and extraction is improved.
Driven gear 9 uses driving gear 7 to distribute as the even circumference in center, and the interior diapire of test tube shell 12 sets up for oval chamfer, and driven gear 9's distribution makes and does not have the interference between each test tube shell 12, and the bottom setting of test tube shell 12 is favorable to placing of test tube.
The clamping mechanism 13 comprises a rotating ring 131, a plane gear 132, two rotating gears 133, two threaded rods 134, two rotating joints 135, two clamping plates 136, two clamping pads 137 and four limiting rods 138, the rotating ring 131 is rotatably connected with the outer side of the test tube shell 12, the plane gear 132 is fixedly connected with the bottom of the rotating ring 131, the two rotating gears 133 are symmetrically distributed on the left side and the right side of the test tube shell 12, one ends of the two threaded rods 134 are respectively fixedly connected with one sides of the two rotating gears 133 close to the test tube shell 12, the two rotating joints 135 are respectively fixedly connected with the other ends of the two threaded rods 134, the two clamping plates 136 are respectively rotatably connected with the two rotating joints 135, the two clamping pads 137 are respectively fixedly connected with the outer sides of the two clamping plates 136, the four limiting rods 138 are uniformly distributed on the left side and the right side of the test tube shell 12 and are respectively fixedly connected with the outer sides of the clamping plates 136, can fix the test tube of different diameters size to it is fixed stable, guarantee the stability of test tube at the in-process that carries out the separation and draw, guarantee the quality of drawing.
The inboard fixedly connected with annular sliding strip of swivel ring 131, the annular spout that matches with annular sliding strip is seted up in the outside of test tube shell 12, utilizes annular sliding strip can guarantee swivel ring 131's slip stability, and then can guarantee swivel ring 131 and stably drive the rotation of running gear 133 when rotating.
The outside of bull gear 133 meshes with the bottom of face gear 132 mutually, threaded rod 134 and the lateral wall threaded connection of test tube shell 12, the sliding hole that matches with gag lever post 138 is seted up to the lateral wall of test tube shell 12, gag lever post 138 and the lateral wall sliding connection of test tube shell 12, grip pad 137 adopts rubber products, the rotation of top fixedly connected with evenly distributed of swivel ring 131 is detained, threaded rod 134 and the removal that test tube shell 12 threaded connection can drive threaded rod 134 when swivel ring 131 rotates, utilize gag lever post 138 to threaded rod 134, the removal of grip block 136 is restricted, grip pad 137 adopts rubber products can increase frictional force and guarantees the stability to the test tube centre gripping, it conveniently detains the rotation to swivel ring 131 to rotate.
The implementation mode specifically comprises the following steps: before placing the test tube, start ultraviolet tube 11, ultraviolet tube 11 sterilizes the inside of separator 1, then turn the case lid 2 open, close ultraviolet tube 11, place the test tube that is equipped with the stem cell in test tube shell 12 respectively, detain the rotation swivel 131 through rotating at this moment, swivel 131 drives the rotation of face gear 132, face gear 132 drives the rotation of swivel gear 133, swivel gear 133 drives the rotation of threaded rod 134 in the rotation process, threaded rod 134 rotates and can make threaded rod 134 move to the inboard of test tube shell 12 and drive rotary joint 135, grip block 136, grip block 137 is close to and centre gripping test tube to the test tube, guarantee the stability of test tube in the separation extraction process, cooperation rotary joint 135, gag lever post 138, guarantee that grip block 136 can the lateral shifting, and can fix the test tube of different diameter size through the removal of control grip block 136, after fixing the test tube, be connected case lid 2 with the top of separator box 1, starter motor 5 this moment, the output of motor 5 drives the rotation of transmission shaft 6, transmission shaft 6 drives driving gear 7 and is located the rotation of the rotary disk 10 at its top, driving gear 7 drives a plurality of driven gear 9, dwang 8, the rotation of rotary disk 10, make a plurality of test tube shells 12 synchronous rotation and then act on the stem cell in the test tube, separate, act on a plurality of test tubes simultaneously and improve separation efficiency.
The foregoing shows and describes the general principles and broad features of the present invention and advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are given by way of illustration of the principles of the present invention, but that various changes and modifications may be made without departing from the spirit and scope of the utility model, and such changes and modifications are within the scope of the utility model as claimed. The scope of the utility model is defined by the appended claims and equivalents thereof.

Claims (7)

1. The utility model provides a separator for stem cell processing, includes separator box (1), its characterized in that, the top of separator box (1) is provided with case lid (2), the bottom fixedly connected with go-between (3) of case lid (2), inboard fixedly connected with backup pad (4) of separator box (1), the interior diapire fixedly connected with motor (5) of separator box (1), the output fixedly connected with transmission shaft (6) of motor (5), backup pad (4) and fixedly connected with driving gear (7) are run through at the top of transmission shaft (6), the top of backup pad (4) is rotated and is connected with a plurality of evenly distributed's dwang (8), and is a plurality of the equal fixedly connected with driven gear (9) in the outside of dwang (8), and is a plurality of the top of dwang (8) and the equal fixedly connected with rotary disk (10) in top of transmission shaft (6), the top of the rotating disc (10) is fixedly connected with a plurality of test tube shells (12), the test tube shells (12) are provided with clamping mechanisms (13), and the bottom of the box cover (2) is fixedly connected with an ultraviolet lamp tube (11).
2. The separation device for stem cell processing according to claim 1, wherein: the outer side of the connecting ring (3) is provided with threads, and the top of the separating box (1) is provided with an annular groove matched with the connecting ring (3).
3. The separation device for stem cell processing according to claim 1, wherein: the transmission shaft (6) is rotatably connected with the middle of the support plate (4), and the outer side of the driving gear (7) is meshed with the outer sides of the driven gears (9).
4. The separation device for stem cell processing according to claim 1, wherein: the driven gears (9) are uniformly distributed in the circumferential direction by taking the driving gear (7) as the center, and the inner bottom wall of the test tube shell (12) is arranged in an elliptical chamfer mode.
5. The separation device for stem cell processing according to claim 1, wherein: the clamping mechanism (13) comprises a rotating ring (131), a plane gear (132), two rotating gears (133), two threaded rods (134), two rotating joints (135), two clamping plates (136), two clamping pads (137) and four limiting rods (138), the rotating ring (131) is rotatably connected with the outer side of the test tube shell (12), the plane gear (132) is fixedly connected with the bottom of the rotating ring (131), the two rotating gears (133) are symmetrically distributed on the left side and the right side of the test tube shell (12), one ends of the two threaded rods (134) are fixedly connected with one sides, close to the test tube shell (12), of the two rotating gears (133) respectively, the two rotating joints (135) are fixedly connected with the other ends of the two threaded rods (134) respectively, and the two clamping plates (136) are rotatably connected with the two rotating joints (135) respectively, two centre gripping pad (137) respectively with the outside fixed connection of two grip blocks (136), four gag lever post (138) evenly distributed just all with the outside fixed connection of grip block (136) in the left and right both sides of test tube shell (12).
6. The separation device for stem cell processing according to claim 5, wherein: the inner side of the rotating ring (131) is fixedly connected with an annular sliding strip, and the outer side of the test tube shell (12) is provided with an annular sliding groove matched with the annular sliding strip.
7. The separation device for stem cell processing according to claim 5, wherein: the outside of running gear (133) meshes with the bottom of face gear (132), threaded rod (134) and the lateral wall threaded connection of test tube shell (12), the slide opening that matches with gag lever post (138) is seted up to the lateral wall of test tube shell (12), gag lever post (138) and the lateral wall sliding connection of test tube shell (12), centre gripping pad (137) adopt rubber products, the top fixedly connected with evenly distributed of rotating ring (131) is detained.
CN202122865026.0U 2021-11-22 2021-11-22 Separator is used in stem cell processing Active CN216946938U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122865026.0U CN216946938U (en) 2021-11-22 2021-11-22 Separator is used in stem cell processing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122865026.0U CN216946938U (en) 2021-11-22 2021-11-22 Separator is used in stem cell processing

Publications (1)

Publication Number Publication Date
CN216946938U true CN216946938U (en) 2022-07-12

Family

ID=82305604

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202122865026.0U Active CN216946938U (en) 2021-11-22 2021-11-22 Separator is used in stem cell processing

Country Status (1)

Country Link
CN (1) CN216946938U (en)

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