CN216924925U

CN216924925U - Freeze dryer for cordyceps sinensis

Info

Publication number: CN216924925U
Application number: CN202123382810.2U
Authority: CN
Inventors: 胡怡; 郭静; 张; 陈丹青; 吴咏梅
Original assignee: Shanghai Pharma Shenxiang Health Pharmaceutical Co ltd
Current assignee: Shanghai Pharma Shenxiang Health Pharmaceutical Co ltd
Priority date: 2021-12-29
Filing date: 2021-12-29
Publication date: 2022-07-08
Anticipated expiration: 2031-12-29

Abstract

A freeze dryer for Cordyceps sinensis comprises: freeze-drying case, the vacuum pump, the cold trap, the control valve, first capacitance pressure gauge, first pirani pressure gauge, second capacitance pressure gauge and second pirani pressure gauge, the condenser chamber of freeze-drying incasement passes through pipeline and vacuum pump connection, be equipped with cold trap and control valve between vacuum pump and the condenser chamber, be equipped with first capacitance pressure gauge and first pirani pressure gauge in the drying intracavity of freeze-drying incasement, the condenser intracavity of freeze-drying incasement is equipped with second capacitance pressure gauge and second pirani pressure gauge. Compared with the prior art, the utility model realizes the optimal control of pressure and vacuum degree in the freeze drying process by adding 2 sets of capacitance pressure gauges and Pirani pressure gauges in the drying cavity and the condenser cavity and matching with a newly added control valve between the vacuum pump and the cold trap.

Description

Freeze dryer for cordyceps sinensis

Technical Field

The utility model relates to the field of traditional Chinese medicine processing, in particular to a cordyceps sinensis freeze-drying machine.

Background

At present, the leading edge of the drying technology of the cordyceps sinensis is freeze drying, and compared with the traditional drying mode, the efficiency is better, the preservation effect is better, and simultaneously, the cordyceps sinensis can be softened. The existing freeze drying technology is quite mature, but the freeze drying equipment is still in a universal model, so that a plurality of freeze drying technologies cannot effectively aim at the cordyceps sinensis, specifically the temperature and pressure control, and further the pressure control.

In order to solve the above problems, we have made a series of improvements.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a cordyceps sinensis freeze dryer to overcome the defects in the prior art.

A freeze dryer for Cordyceps sinensis comprises: freeze-drying case, vacuum pump, cold trap, control valve, first capacitance pressure gauge, first pirani pressure gauge, second capacitance pressure gauge and second pirani pressure gauge, the condenser chamber of freeze-drying incasement passes through pipeline and vacuum pump connection, be equipped with cold trap and control valve between vacuum pump and the condenser chamber, be equipped with first capacitance pressure gauge and first pirani pressure gauge in the dry chamber of freeze-drying incasement, the condenser intracavity of freeze-drying incasement is equipped with second capacitance pressure gauge and second pirani pressure gauge.

Further, the lyophilization chamber comprises: dry chamber, condenser chamber, separation wall, blowing case, door, the structure and the cooling device of giving vent to anger, dry chamber and condenser chamber are through separation wall alternate segregation in the casing of freeze-drying case, the upper end of the junction of dry chamber, condenser chamber and separation wall is equipped with opening and electric control valve, the door is connected with dry chamber, dry intracavity is located to the blowing case, the structure and the blowing incasement of giving vent to anger is connected, be equipped with the thermometer in the blowing case, cooling device locates the condenser intracavity.

The utility model has the beneficial effects that:

compared with the prior art, the utility model realizes the optimal control of pressure and vacuum degree in the freeze drying process by adding 2 sets of capacitance pressure gauges and Pirani pressure gauges in the drying cavity and the condenser cavity and matching with a newly added control valve between the vacuum pump and the cold trap.

Description of the drawings:

FIG. 1 is a schematic structural diagram of the present invention.

Reference numerals:

a freeze drying chamber 100, a drying chamber 110, a condenser chamber 120, a separating wall 130, a blow down chamber 140, a door 150, a vent structure 160, and a cooling device 170.

Vacuum pump 200, cold trap 300, control valve 400, first capacitance manometer 500, first pirani manometer 600, second capacitance manometer 700, and second pirani manometer 800.

Detailed Description

The present invention will be further described with reference to the following examples. It should be understood that the following examples are illustrative only and are not intended to limit the scope of the present invention.

Example 1

FIG. 1 is a schematic structural diagram of the present invention.

As shown in fig. 1, a cordyceps sinensis freeze dryer comprises: freeze-drying case 100, vacuum pump 200, cold trap 300, control valve 400, first capacitance manometer 500, first pirani manometer 600, second capacitance manometer 700 and second pirani manometer 800, the condenser chamber in freeze-drying case 100 passes through the pipeline and is connected with vacuum pump 200, be equipped with cold trap 300 and control valve 400 between vacuum pump 200 and the condenser chamber, be equipped with first capacitance manometer 500 and first pirani manometer 600 in the dry chamber in freeze-drying case 100, be equipped with second capacitance manometer 700 and second pirani manometer 800 in the condenser intracavity in freeze-drying case 100.

The lyophilization chamber 100 comprises: the drying chamber 110, the condenser chamber 120, the separating wall 130, the discharging box 140, the door 150, the air outlet structure 160 and the cooling device 170, wherein the drying chamber 110 and the condenser chamber 120 are separated from each other in the shell of the freeze-drying box 100 through the separating wall 130, the upper ends of the joints of the drying chamber 110, the condenser chamber 120 and the separating wall 130 are provided with openings and electric control valves, the door 150 is connected with the drying chamber 110, the discharging box 140 is arranged in the drying chamber 110, the air outlet structure 160 is connected with the discharging box 140, a thermometer is arranged in the discharging box 140, and the cooling device 170 is arranged in the condenser chamber 120.

The basic principle of the lyophilization chamber 100 of the present invention is consistent with the conventional art, except that the present invention adds a device that better enables pressure control. From the background art, it can be easily found that the present freeze-drying technology of cordyceps sinensis requires very precise pressure control and continuous adjustment. But the prior art is difficult to realize.

Firstly, monitoring: the present invention incorporates capacitance and pirani gauges in both the dry chamber 110 and the condenser chamber 120, which allow for comparative pressure measurements. In this process analysis method, the chamber pressure was measured and controlled using a capacitance manometer, while the pressure was monitored using a pirani manometer. By utilizing the gas phase composition dependency of the raney vacuum gauge, the output variation of the apparatus reflects the variation of the gas phase composition when the process transits from the primary drying to the secondary drying, and the cycle from the primary drying to the secondary drying is ordered according to the difference in apparent pressure between the capacitance manometer and the pirani manometer. This solution does not rely on monitoring a single drying oven for Cordyceps sinensis, but on the composition of the gas phase in the drying chamber 110.

Secondly, the operation control: the operation process is based on a capacitance manometer to control the pressure of the drying chamber 110, and if only a pirani manometer is installed, then the pirani manometer is used for control, because there is a possibility that the critical product temperature may be exceeded when the process is performed near the critical product temperature near the end of the primary drying. As the relative partial pressure of water vapor decreases, the nitrogen flow rate increases to maintain the set point. This leads to increased absolute pressure, increased heat transfer, increased product temperature and increased product risk. In contrast, the capacitance manometer, because the ratio of the drying chamber 110 pressure to the condenser chamber 120 pressure, can be a measure of the performance of the equipment, makes it almost a standard measure for a conventional freeze dryer.

And the pirani gauge occasionally leaks somewhere in the system, preventing any vacuum from building up. Both are installed to help quickly locate the source of the leak. Although a pirani gauge may be less accurate at sub-atmospheric pressures, this is not important for this type of troubleshooting.

The conclusion is the theoretical basis for installing two sets of equipment at two places simultaneously.

And the utility model adopts a bidirectional control mode to control the pressure and the vacuum degree.

In the upstream control mode, the gas flowing into the drying chamber 110 is controlled by an electrically controlled valve. The upstream control mode is to maintain the pressure upstream of the vacuum system itself, and to increase the intake air flow rate to decrease the pressure and decrease the intake air flow rate to increase the pressure under a constant pumping speed of the vacuum pump 200. The main characteristics are as follows: the stability and the speed of the process in the vacuum system can be improved; using a fast acting control valve, placing the control instrument upstream of the vacuum system may provide faster response times and better stability. The upstream mode also eliminates the need for additional valves, reduces the number of potential leak points in the system, reduces the need for downstream equipment, and reduces installation costs. The control of the slope of pressure change can be conveniently carried out, the air inlet can continuously bring the sublimation gas into the cold trap, and the method is greatly helpful for the bulk sample process. The disadvantage of the upstream control mode is that it is relatively gas-consuming, especially when the feed gas is some relatively expensive high purity inert gas.

The present invention adds the cold trap 300 on the conventional basis, and the cold trap 300 is not a standard part in the conventional apparatus, and in order to match the above improvement, it is necessary to implement the downstream control mode and replace the conventional valve with the adjustable control valve 400.

The downstream control mode is a mode for controlling the pumping, that is, the pumping speed of the vacuum pump 200 is controlled by controlling and adjusting the opening of the control valve 400 between the vacuum pump 200 and the cold trap 300, so as to control the pressure. The main characteristics are as follows: the downstream mode is used as a current common control mode, can work well under various conditions generally, and has the biggest characteristic that extra gas cannot enter and the air inflow is saved relatively; but during downstream mode control, its effectiveness can sometimes be challenged by "external" factors, such as sudden changes in inlet gas flow rate or sudden changes in the internal chamber gas pressure. In addition, certain combinations of flow and pressure may force the valve to operate at or beyond the limits of its intended control range. In this case, neither accurate nor repeatable pressure control is feasible. Alternatively, pressure control may be possible, but not in a fast and efficient manner, with the result that product yield and yield are affected. In the downstream mode, delays may be incurred when replacing gas or waiting for gas to settle in the chamber. If the valve is a simple on-off valve, the pressure in this mode is not as accurate and stable as the pressure in the upstream mode, and pressure ramp control is difficult to achieve.

Therefore, the present invention combines the two modes according to different situations.

While the present invention has been described with reference to the specific embodiments, the present invention is not limited thereto, and various changes may be made without departing from the spirit of the present invention.

Claims

1. A freeze dryer for Cordyceps sinensis is characterized in that: the method comprises the following steps: freeze-drying case (100), vacuum pump (200), cold trap (300), control valve (400), first capacitance manometer (500), first pirani manometer (600), second capacitance manometer (700) and second pirani manometer (800), the condenser chamber in freeze-drying case (100) passes through the pipeline and is connected with vacuum pump (200), be equipped with cold trap (300) and control valve (400) between vacuum pump (200) and the condenser chamber, be equipped with first capacitance manometer (500) and first pirani manometer (600) in the dry chamber in freeze-drying case (100), be equipped with second capacitance manometer (700) and second pirani manometer (800) in the condenser chamber in freeze-drying case (100).

2. The freeze dryer for cordyceps sinensis according to claim 1, wherein: the lyophilization chamber (100) comprises: drying chamber (110), condenser chamber (120), separating wall (130), blowing case (140), door (150), the structure (160) and cooling device (170) of giving vent to anger, drying chamber (110) and condenser chamber (120) are through separating wall (130) alternate segregation in the casing of freeze-drying case (100), the upper end of the junction of drying chamber (110), condenser chamber (120) and separating wall (130) is equipped with opening and electric control valve, door (150) are connected with drying chamber (110), in drying chamber (110) was located in blowing case (140), it is connected with blowing case (140) to give vent to anger structure (160), be equipped with the thermometer in blowing case (140), cooling device (170) are located in condenser chamber (120).