CN216910116U

CN216910116U - Aseptic processing system of freeze-dried powder injection production

Info

Publication number: CN216910116U
Application number: CN202123381229.9U
Authority: CN
Inventors: 侯西成; 王学智; 王哲; 耿艳杰; 张金萍; 王振刚
Original assignee: Hebei Daoen Pharmaceutical Co ltd
Current assignee: Hebei Daoen Pharmaceutical Co ltd
Priority date: 2021-12-30
Filing date: 2021-12-30
Publication date: 2022-07-08
Anticipated expiration: 2031-12-30

Abstract

The utility model discloses a sterile treatment system for producing a freeze-dried powder injection, relates to the technical field of freeze-dried powder processing, and solves the problems that a filtering mechanism part is contacted with liquid medicine for filtering, and the use conditions of the filtering mechanism are inconsistent. The sterile treatment system for freeze-dried powder injection production comprises a first liquid preparation tank; a first transparent plate is vertically arranged in the middle of the first liquid distribution tank and is of a transparent plate-shaped structure; the bottom of the first liquid preparation tank is in through connection with a connecting pipe; the connecting pipe top link up with the pump body, the fixed control module that is provided with in pump body top goes up the fixed antenna that is provided with in control module top, antenna and last control module circuit connection, pump body liquid outlet pass through the center through connection of pipeline with the filter core jar. This practicality is through the rotation of inner filter core, and the inner filter core rotates and filters the contact with the liquid medicine, and the inner filter core uses more high-efficient and each part life-span more unanimously.

Description

Aseptic processing system of freeze-dried powder injection production

Technical Field

The utility model belongs to the technical field of freeze-dried powder processing, and particularly relates to a sterile treatment system for freeze-dried powder injection production.

Background

The freeze dried powder for injection is prepared through freezing medicine liquid in aseptic environment, mixing the medicine liquid with some supplementary material or dissolving in some solvent, and certain technological process.

Based on the aforesaid, still need carry out the preparation of liquid medicine earlier before the freeze-drying of freeze-dried powder injection, still need carry out the multiple-layer filtering with liquid medicine configuration after and reach, current filtration is mostly fixed the setting, when production load is lower, can make inside filter mechanism part and liquid medicine contact filtration, another part contactless for each part life consumption inconsistent of filter mechanism, change in advance, the economic nature is low.

SUMMERY OF THE UTILITY MODEL

In order to solve the technical problems, the utility model provides the sterile treatment system for producing the freeze-dried powder injection, the inner filter core is in alternative filtering contact with the liquid medicine through the rotation of the inner filter core, and the inner filter core is more uniform and consistent in use.

The purpose and the effect of the sterile treatment system for producing the freeze-dried powder injection are achieved by the following specific technical means:

the sterile treatment system for freeze-dried powder injection production comprises a first liquid preparation tank; a first transparent plate is vertically arranged in the middle of the first liquid preparation tank, the first transparent plate is of a transparent plate-shaped structure, and the state of liquid medicine in the first liquid preparation tank is checked by the first transparent plate; the bottom of the first liquid preparation tank is connected with a connecting pipe in a run-through manner; the top end of the connecting pipe is communicated with the pump body, the top of the pump body is fixedly provided with an upper control module, the top of the upper control module is fixedly provided with an antenna, the antenna is in circuit connection with the upper control module, the upper control module is in circuit connection with the pump body control circuit, the liquid inlet of the pump body is communicated with the connecting pipe with a hollow tubular structure, and the liquid outlet of the pump body is in through connection with the center of the filter element tank through a pipeline; a liquid outlet at the tail end of the pump body is communicated with a pipeline of the filter element tank, an annular inner rotating ring is fixedly arranged inside the filter element tank, the inner rotating ring is connected with the inner filter element in an embedded and rotating manner, the inner filter element is provided with guide bars in an annular array manner, the inner filter element is of a filter membrane structure, the guide bars are fixedly arranged at the front part of the inner filter element, the guide bars and a liquid inlet of the filter element tank are arranged in opposite directions, and a liquid outlet of the filter element tank is arranged at the bottom of the tail end; the outlet at the tail end of the filter element tank is communicated with a second liquid distribution tank pipeline, a second permeable plate is vertically and fixedly arranged in the middle of the second liquid distribution tank, the bottom of the second liquid distribution tank is communicated with a connecting pipe, the tail end of the connecting pipe is communicated with the filter element tank, the tail end of the filter element tank is communicated with a central pipeline of a third liquid distribution tank, a plurality of filter element tanks are connected in series at the front section of the second liquid distribution tank, inner filter elements in the plurality of filter element tanks are respectively of filtering types of 0.65 mu m, 0.45 mu m or 0.2 mu m, and the plurality of filter element tanks are communicated end to end; the fluid reservoir rear portion is joined in marriage to the second still is provided with the third and joins in marriage the fluid reservoir, and the third is joined in marriage the fixed third board that is provided with in fluid reservoir middle part, and the third board and the second board that pass through are transparent platelike structure, and the third passes through board and the second board that passes through to look over the state that the fluid reservoir was joined in marriage to the third and the inside liquid medicine of fluid reservoir is joined in marriage to the second, makes things convenient for the visitor to contrast the show, and the fluid reservoir anterior segment is joined in marriage to the third is provided with a plurality of filter element jars, and the inside inner filter core of filter element jar is 0.2 mu m model, a plurality of filter element jars end to end series connection intercommunication.

The utility model at least comprises the following beneficial effects:

1. the liquid medicine drives the inner filter element to rotate, so that the filtering consumption of the inner filter element is more uniform in a non-full-load running state, the inner filter element is more efficiently and thoroughly used, the service cycle of the inner filter element is prolonged, and the use is more economical and efficient.

2. According to the utility model, the liquid medicine is filtered by the filter element tanks with different filtering types, the aseptic requirement is finally met, the operating state of the pump body is remotely checked and controlled by the upper control module and the antenna, and the patrol monitoring of personnel is reduced.

Drawings

FIG. 1 is a schematic three-dimensional structure of the present invention.

Fig. 2 is a schematic diagram of a half-section structure of a filter element tank of the utility model.

Fig. 3 is a schematic view of the pump body structure of the present invention.

FIG. 4 is a schematic view of the split structure of the present invention.

In the drawings, the corresponding relationship between the component names and the reference numbers is as follows:

1. a first liquid preparation tank; 101. a first transparent plate; 2. a connecting pipe; 3. a second liquid preparation tank; 301. a second transparent plate; 4. a pump body; 401. an upper control module; 402. an antenna; 5. a filter element tank; 501. an inner swivel; 502. an inner filter element; 503. conducting bars; 6. a third liquid preparation tank; 601. and a third transparent plate.

Detailed Description

The embodiments of the present invention will be described in further detail with reference to the drawings and examples. The following examples are intended to illustrate the utility model but are not intended to limit the scope of the utility model.

In the description of the present invention, "a plurality" means two or more unless otherwise specified; the terms "coaxial," "bottom," "one end," "top," "middle," "other end," "upper," "side," "top," "inner," "front," "center," "two ends," and the like are used in an orientation or positional relationship indicated in the drawings for convenience in describing and simplifying the description, and are not intended to indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the utility model. Furthermore, the terms "first," "second," "third," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless explicitly stated or limited otherwise, the terms "mounted," "disposed," "connected," "fixed," "screwed" and the like are to be understood broadly, and for example, they may be fixedly connected, detachably connected, or integrated; can be mechanically or electrically connected; the terms may be directly connected or indirectly connected through an intermediate, and may be communication between two elements or interaction relationship between two elements, unless otherwise specifically limited, and the specific meaning of the terms in the present invention will be understood by those skilled in the art according to specific situations.

Example (b):

as shown in figures 1 to 4:

the utility model provides a sterile processing system for producing freeze-dried powder injection, which comprises a first liquid preparation tank 1; a first transparent plate 101 is vertically arranged in the middle of the first liquid preparation tank 1, the first transparent plate 101 is of a transparent plate-shaped structure, and the state of liquid medicine in the first liquid preparation tank 1 is checked through the first transparent plate 101; the bottom of the first liquid preparation tank 1 is connected with a connecting pipe 2 in a run-through manner; the top end of the connecting pipe 2 is communicated with the pump body 4, the liquid inlet of the pump body 4 is communicated with the connecting pipe 2 with a hollow tubular structure, the liquid outlet of the pump body 4 is communicated with the center of the filter element tank 5 through a pipeline, the top of the pump body 4 is fixedly provided with an upper control module 401, the top of the upper control module 401 is fixedly provided with an antenna 402, the antenna 402 is in circuit connection with the upper control module 401, the upper control module 401 is in circuit connection with the pump body 4, the upper control module 401 is connected with the internet through the upper control module 401 and the antenna 402, the running state of the pump body 4 is checked and controlled remotely, and the patrol monitoring of personnel is reduced;

a liquid outlet at the tail end of the pump body 4 is communicated with a pipeline of the filter element tank 5; an outlet at the tail end of the filter element tank 5 is communicated with a pipeline of the second liquid preparation tank 3, a second permeable plate 301 is vertically and fixedly arranged in the middle of the second liquid preparation tank 3, the bottom of the second liquid preparation tank 3 is communicated with a connecting pipe 2, the tail end of the connecting pipe 2 is communicated with the filter element tank 5, the tail end of the filter element tank 5 is communicated with a central pipeline of the third liquid preparation tank 6, a plurality of filter element tanks 5 are arranged in series at the front section of the second liquid preparation tank 3, the inner filter elements 502 in the plurality of filter element tanks 5 are respectively of filtering types of 0.65 mu m, 0.45 mu m or 0.2 mu m, the plurality of filter element tanks 5 are communicated end to end, multiple filtering is carried out, and the filtering effect is improved; the second is joined in marriage the fluid reservoir 3 rear portion and still is provided with the third and joins in marriage fluid reservoir 6, the third is joined in marriage fluid reservoir 6 middle part and is fixed and be provided with third pass board 601, third pass board 601 and second pass board 301 are transparent platelike structure, third pass board 601 and second pass board 301 look over the third and join in marriage the state that fluid reservoir 6 and the inside liquid medicine of fluid reservoir 3 were joined in marriage to the third, make things convenient for the visitor to contrast the show, the third is joined in marriage and is provided with a plurality of filter core jars 5 in the 6 anterior segment treatment flows of fluid reservoir, the inside inner filter core 502 of filter core jar 5 is 0.2 mu m model, 5 end to end series intercommunication of a plurality of filter core jars, filter core jar 5 liquid medicine filters.

Referring to fig. 1 and 2, the filter core jar 5 is inside to be fixed and to be provided with annular adversion ring 501, adversion ring 501 rotates with the embedding of interior filter core 502 to be connected, interior filter core 502 circular array is provided with gib 503, interior filter core 502 is the filtration membrane structure, gib 503 is fixed to be set up at the front portion of interior filter core 502, gib 503 is opposite direction setting with the inlet of filter core jar 5, the liquid outlet of filter core jar 5 sets up the bottom at the tail end, reduce the residue of the inside liquid medicine of filter core jar 5, when non-full load or low-load running state, the liquid medicine is in filter core jar 5 the latter half, change with the liquid medicine contact through making the rotation of interior filter core 502 and filter, the filtration consumption of each part of interior filter core 502 is more even, interior filter core 502 uses more high-efficient and thorough, the life cycle of extension interior filter core 502.

The specific use mode and function of the embodiment are as follows:

in the utility model, after the liquid medicine is prepared, the liquid medicine enters a first liquid preparation tank 1, a pump body 4 filters the liquid medicine in the first liquid preparation tank 1 to a filter element tank 5 through a plurality of filter element tanks 5 of filter elements 502 with different filtering types of 0.65 mu m, 0.45 mu m or 0.2 mu m, the filtering pressure is 0.5-3bar, the filtering time is 10-50min, the liquid medicine firstly passes through the filter element tank 5 with 0.65 mu m, then passes through 0.45 mu m, and finally passes through a filter tube with 0.2 mu m to be filtered to enter a second liquid preparation tank 3, the liquid medicine in the second liquid preparation tank 3 is pumped to a third liquid preparation tank 6 by a pump body 4 at the rear part, the liquid medicine is firstly filtered by a plurality of filter element tanks 5 before entering the third liquid preparation tank 6, a plurality of filter element tanks 5 can be repeatedly arranged for keeping the filtering effect, the filter element tanks 5 are inner filter elements 502 with the inner part of 0.2 mu m level, the filtering pressure is 0.5-3bar, and the filtering time is 10-50min, the inside liquid medicine of fluid reservoir 6 reaches aseptic requirement is joined in marriage to final third, be connected with the internet through last control module 401 and antenna 402, long-range running state who looks over and control the pump body 4, reduce personnel's inspection monitoring, it removes to drive conducting bar 503 through the liquid medicine flow, conducting bar 503 and interior filter core 502 rotate along interior swivel 501, when non-full load or low-load running state, the liquid medicine is in filter core jar 5 the latter half, change through the rotation that makes interior filter core 502 and filter with the liquid medicine contact, the filtration consumption of interior filter core 502 each part is more even, interior filter core 502 uses more high-efficient and thoroughly, the life cycle of extension interior filter core 502, use economy and high-efficient more, interior filter core 502 can be the funnel-shaped structure, increase the area of interior filter core 502, increase the area of contact of interior filter core 502 with the liquid medicine.

The utility model is not described in detail, but is well known to those skilled in the art.

The embodiments of the present invention have been presented for purposes of illustration and description, and are not intended to be exhaustive or limited to the utility model in the form disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiment was chosen and described in order to best explain the principles of the utility model and the practical application, and to enable others of ordinary skill in the art to understand the utility model for various embodiments with various modifications as are suited to the particular use contemplated.

Claims

1. Aseptic processing system of freeze-dried powder injection production, its characterized in that: the sterile treatment system for freeze-dried powder injection production comprises a first liquid preparation tank (1); the bottom of the first liquid distribution tank (1) is connected with a connecting pipe (2) in a through way; the top end of the connecting pipe (2) is communicated with the pump body (4); a liquid outlet at the tail end of the pump body (4) is communicated with a pipeline of the filter element tank (5); the outlet at the tail end of the filter element tank (5) is communicated with the pipeline of the second liquid preparation tank (3); a third liquid preparation tank (6) is also arranged at the rear part of the second liquid preparation tank (3); the filter element tank (5) is internally and fixedly provided with an annular inner rotating ring (501), the inner rotating ring (501) is embedded into the inner filter element (502) to be rotatably connected, and the inner filter element (502) is provided with guide bars (503) in an annular array.

2. The sterile processing system for the production of the freeze-dried powder injection as claimed in claim 1, wherein a first transparent plate (101) is vertically arranged in the middle of the first liquid preparation tank (1), and the first transparent plate (101) is of a transparent plate-shaped structure.

3. The sterile treatment system for the production of the freeze-dried powder injection according to claim 1, wherein an upper control module (401) is fixedly arranged at the top of the pump body (4), an antenna (402) is fixedly arranged at the top of the upper control module (401), the antenna (402) is in circuit connection with the upper control module (401), and the upper control module (401) is in circuit connection with the pump body (4).

4. The sterile treatment system for the production of the freeze-dried powder injection according to claim 1, wherein a liquid inlet of the pump body (4) is communicated with the connecting pipe (2) with a hollow tubular structure, and the pump body (4) is communicated with the center of the filter element tank (5) through a pipeline.

5. The sterile processing system for the production of the freeze-dried powder injection as claimed in claim 1, wherein the guide strip (503) is fixedly arranged at the front part of the inner filter element (502), the guide strip (503) is arranged opposite to the liquid inlet of the filter element tank (5), and the liquid outlet of the filter element tank (5) is arranged at the bottom of the tail end.

6. The sterile treatment system for the production of the freeze-dried powder injection as claimed in claim 1, wherein a second transparent plate (301) is vertically and fixedly arranged in the middle of the second liquid preparation tank (3), the bottom of the second liquid preparation tank (3) is connected with a connecting pipe (2) in a through manner, a filter element tank (5) is arranged at the tail end of the connecting pipe (2) in a through manner, the tail end of the filter element tank (5) is communicated with the central pipeline of a third liquid preparation tank (6), a third transparent plate (601) is fixedly arranged in the middle of the third liquid preparation tank (6), and the third transparent plate (601) and the second transparent plate (301) are both transparent plate-like structures.

7. The sterile treatment system for the production of the freeze-dried powder injection as claimed in claim 1, wherein the inner filter element (502) arranged in series at the front section of the second liquid preparation tank (3) is a filter element tank (5) with the filtering type of 0.65 μm and 0.45 μm which is communicated end to end.

8. The sterile treatment system for the production of the freeze-dried powder injection as claimed in claim 1, wherein the inner filter element (502) in the filter element tank (5) arranged at the front section of the third liquid preparation tank (6) is of a 0.2 μm type, and a plurality of filter element tanks (5) are communicated in series end to end.