CN216890920U - Nucleic acid extraction and PCR amplification detection device - Google Patents
Nucleic acid extraction and PCR amplification detection device Download PDFInfo
- Publication number
- CN216890920U CN216890920U CN202220434003.6U CN202220434003U CN216890920U CN 216890920 U CN216890920 U CN 216890920U CN 202220434003 U CN202220434003 U CN 202220434003U CN 216890920 U CN216890920 U CN 216890920U
- Authority
- CN
- China
- Prior art keywords
- base
- wall
- nucleic acid
- connecting rod
- rigid coupling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a nucleic acid extraction and PCR amplification detection device, which comprises a base and a PCR instrument, wherein the PCR instrument is installed on the outer wall of the base, a protection component is installed inside the base, a cylinder is connected with the base in a sleeved mode, a protection plate is fixedly connected to the outer wall of the cylinder, a connecting rod is sleeved inside the cylinder in a sleeved mode, an inserting disc is fixedly connected to one end of the connecting rod, a sliding block is fixedly connected to the other end of the connecting rod, a groove plate is fixedly connected to the inner cavity of the cylinder, and an elastic part is installed on the outer wall of the connecting rod. The utility model relates to the technical field of nucleic acid detection, and discloses a nucleic acid extraction and PCR amplification detection device.
Description
Technical Field
The utility model relates to the technical field of nucleic acid detection, in particular to a nucleic acid extraction and PCR amplification detection device.
Background
Nucleic acid detection plays an important role in many biochemical analysis fields such as clinical medicine, forensic identification, genetic test and the like, and is widely applied to the fields of biological medicine and the like, in the prior art, a centrifugal column method or a magnetic bead method is generally used for nucleic acid extraction, four steps such as cracking, combination, cleaning, elution and the like are generally required, and the subsequent detection steps such as nucleic acid molecule hybridization, Polymerase Chain Reaction (PCR), biochip and the like are added, so that the whole full-automatic instrument from a sample to a result is very difficult to realize, and the PCR instrument is required to be used as a detection device when the nucleic acid detection is carried out.
However, when the existing nucleic acid extraction and PCR amplification detection device is used for amplification detection by using a PCR instrument, a control panel of the PCR instrument is externally arranged, and the detection result of nucleic acid is influenced by error touch.
Disclosure of Invention
Aiming at the defects of the prior art, the utility model provides a nucleic acid extraction and PCR amplification detection device, which solves the problem that when a PCR instrument is used for amplification detection, a control panel of the PCR instrument is externally arranged, and the detection result of nucleic acid is influenced by error touch in the conventional nucleic acid extraction and PCR amplification detection device.
In order to realize the purpose, the utility model is realized by the following technical scheme: a nucleic acid extraction and PCR amplification detection device comprises a base and a PCR instrument, wherein the PCR instrument is installed on the outer wall of the base, and a protection component is installed inside the base;
protection component includes drum, backplate, connecting rod, inserted disc, slider, frid and elastic component:
the drum is connected with the base in a sleeved mode, a protection plate is fixedly connected to the outer wall of the drum, a connecting rod is sleeved inside the drum, an inserting disc is fixedly connected to one end of the connecting rod, a sliding block is fixedly connected to the other end of the connecting rod, a groove plate is fixedly connected to the inner cavity of the drum, an elastic piece is installed on the outer wall of the connecting rod, one end of the elastic piece is attached to the inserting disc, and the other end of the elastic piece is attached to the drum.
Preferably, the outer wall of slider has cup jointed the slide rail, slide rail and drain pan fixed connection, the bolt has been cup jointed to the inside of slide rail, the outer wall of bolt runs through the slide rail and links to each other with the slider screw thread, the drum is kept away from the one end of connecting rod and is installed the sealing plug.
Preferably, the inner cavity of the base is provided with a receiving assembly;
the containing assembly comprises a containing box, a partition plate, a transverse plate and a handle;
the storage box and the base are connected in a sleeved mode, a partition plate is fixedly connected to the inner portion of the storage box, a transverse plate is fixedly connected to one end, far away from the base, of the storage box, and a handle is fixedly connected to one side, far away from the storage box, of the transverse plate.
Preferably, the outer wall of the base is provided with a fixing component;
the fixing component comprises a fixing seat, a threaded rod and a pressing plate;
the fixing seat is fixedly connected with the base, a threaded rod is mounted inside the fixing seat, and a pressing plate is fixedly connected to the outer wall of the threaded rod.
Preferably, the outer wall of the PCR instrument is provided with a control panel, and the top of the PCR instrument is processed with a top cover.
The utility model provides a nucleic acid extraction and PCR amplification detection device. The method has the following beneficial effects: the nucleic acid extraction and PCR amplification detection device is characterized in that a cylinder, a protective plate, a connecting rod, an inserting disc, a sliding block, a groove plate, an elastic piece and the like are matched for use, the sliding block is moved in a sliding rail to drive a bolt to move, the sliding block drives the cylinder and the protective plate to be separated from a base through the connecting rod, then the cylinder is pulled to compress the elastic piece, the protective plate is rotated on the outer wall of the connecting rod and is arranged on the outer wall of a control panel, and the protective plate and the control panel are arranged in parallel to prevent the control panel from being touched by mistake;
through the cooperation use of receiver, baffle, diaphragm and handle etc, use and accomodate PCR appearance nucleic acid detection and accomplish the back, the pulling handle drives diaphragm and receiver and base separation, places other spare parts of PCR appearance in the cavity that baffle and receiver are constituteed afterwards, accomplishes and accomodates, makes things convenient for the secondary to use and prevents that spare part from losing.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a cross-sectional view of the cylinder of FIG. 1;
FIG. 3 is a schematic view of the connection structure of the base, the slide rail and the slide block in FIG. 1;
fig. 4 is a schematic view of a connection structure of the base, the storage box and the partition plate in fig. 1.
In the figure: 1. the base, 2, PCR appearance, 3, protection component, 301, drum, 302, backplate, 303, connecting rod, 304, plug tray, 305, slider, 306, frid, 307, elastic component, 4, slide rail, 5, bolt, 6, sealing plug, 7, accomodate the subassembly, 701, the receiver, 702, baffle, 703, diaphragm, 704, handle, 8, fixed subassembly, 801, fixing base, 802, threaded rod, 803, clamp plate, 9, control panel, 10, top cap.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The following working principles, detailed connecting means thereof, and the following main descriptions of the working principles and processes are well known in the art, and will be referred to by those skilled in the art for the specific connection and operation sequence of the components in this application.
The first embodiment is as follows:
as shown in FIGS. 1, 2 and 3, a nucleic acid extraction and PCR amplification detection device comprises a base 1 and a PCR instrument 2, wherein the PCR instrument 2 is installed on the outer wall of the base 1, a protection component 3 is installed inside the base 1, the protection component 3 comprises a cylinder 301, a protection plate 302, a connecting rod 303, a plug-in tray 304, a sliding block 305, a groove plate 306 and an elastic member 307, the cylinder 301 is connected with the base 1 in a sleeved manner, the protection plate 302 is fixedly connected to the outer wall of the cylinder 301, the connecting rod 303 is sleeved inside the cylinder 301, the plug-in tray 304 is fixedly connected to one end of the connecting rod 303, the sliding block 305 is fixedly connected to the other end of the connecting rod 303, the groove plate 306 is fixedly connected to the inner cavity of the cylinder 301, the elastic member 307 is installed on the outer wall of the connecting rod 303, one end of the elastic member 307 is attached to the plug-in tray 304, the other end of the elastic member 307 is attached to the cylinder 301, the sliding block 305 is sleeved with a sliding rail 4, the sliding rail 4 is fixedly connected to the bottom shell 1, a plug 5 is sleeved inside the sliding rail 4, the outer wall of the bolt 5 penetrates through the sliding rail 4 to be connected with the sliding block 305 in a threaded mode, and a sealing plug 6 is installed at one end, far away from the connecting rod 303, of the cylinder 301;
in the specific implementation process, it is worth noting that a cavity is processed in the base 1, the cylinder 301 and the guard plate 302 can be received in the base 1, the guard plate 302 is made of plastic material, the outer wall of the insert plate 304 is processed with a convex block, the slide block 305 is rectangular, a through hole is processed in the groove plate 306, and the elastic member 307 is a compression spring;
furthermore, the elastic element 307 can be replaced by other mechanical structures, the slider 305 can move in the slide rail 4, the outer wall of the plug 5 is provided with threads, the plug 5 prevents the slider 305 from separating from the slide rail 4, and the sealing plug 6 is detachably connected with the cylinder 301;
specifically, the sliding block 305 is moved in the sliding rail 4 to drive the bolt 5 to move, the sliding block 305 drives the bolt 5 to move in the groove of the sliding rail 4, meanwhile, the sliding block 305 drives the cylinder 301 and the protection plate 302 to separate from the base 1 through the connecting rod 303, then the cylinder 301 is pulled to compress the elastic element 307, the plug disc 304 is separated from the groove plate 306, the protection plate 302 is rotated on the outer wall of the connecting rod 303, and the protection plate 302 is arranged on the outer wall of the control panel 9 to prevent the control panel 9 from being touched by mistake.
Example two:
as can be seen from fig. 1 and 4, the containing assembly 7 is installed in the inner cavity of the base 1, the containing assembly 7 includes a containing box 701, a partition 702, a transverse plate 703 and a grip 704, the containing box 701 and the base 1 are connected in a sleeved manner, the partition 702 is fixedly connected inside the containing box 701, the transverse plate 703 is fixedly connected to one end of the containing box 701 away from the base 1, and the grip 704 is fixedly connected to one side of the transverse plate 703 away from the containing box 701;
in the specific implementation process, it is worth pointing out that the storage box 701 can be embedded into the base 1, the partition plate 702 divides the storage box 701 into different parts for storing other parts of the PCR instrument 2, the outer wall of the transverse plate 703 is fixedly connected with two grips 704, and the grips 704 are conveniently arranged to drive the storage box 701 to move;
specifically, after 2 nucleic acid detection of PCR appearance are accomodate in the use and are accomplished, pulling handle 704 drives the motion of diaphragm 703, and diaphragm 703 drives receiver 701 and the separation of base 1, places other spare parts of PCR appearance 2 in the cavity that baffle 702 and receiver 701 constitute afterwards, and the completion is accomodate.
Example three:
as can be seen from fig. 1, a fixing assembly 8 is mounted on the outer wall of a base 1, the fixing assembly 8 includes a fixing seat 801, a threaded rod 802 and a pressing plate 803, the fixing seat 801 is fixedly connected with the base 1, the threaded rod 802 is mounted inside the fixing seat 801, the pressing plate 803 is fixedly connected to the outer wall of the threaded rod 802, a control panel 9 is mounted on the outer wall of a PCR instrument 2, and a top cover 10 is processed on the top of the PCR instrument 2;
in the specific implementation process, it is worth particularly pointing out that four fixing seats 801 are fixedly connected to the upper surface of the base 1, a threaded rod 802 is installed in each fixing seat 801, the threaded rod 802 drives the pressing plate 803 to move, and the top cover 10 and the control panel are both the prior art of the PCR instrument 2 and are not described in detail;
specifically, the PCR instrument 2 is placed between four fixing seats 801, and then, the threaded rod 802 is rotated in the fixing seats 801, the threaded rod 802 drives the pressing plate 803 to move, the pressing plate 803 is tightly pressed against the PCR instrument 2, and the PCR instrument 2 is further fixed on the surface of the base 1.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation. The use of the phrase "comprising one of the elements does not exclude the presence of other like elements in the process, method, article, or apparatus that comprises the element.
In the present invention, unless otherwise expressly specified or limited, the terms "mounted," "disposed," "connected," "secured," "screwed" and the like are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; the terms may be directly connected or indirectly connected through an intermediate, and may be communication between two elements or interaction relationship between two elements, unless otherwise specifically limited, and the specific meaning of the terms in the present invention will be understood by those skilled in the art according to specific situations.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (5)
1. The utility model provides a nucleic acid extraction and PCR amplifications detection device, includes base (1) and PCR appearance (2), its characterized in that are installed to the outer wall of base (1): a protective component (3) is arranged in the base (1);
the protection assembly (3) comprises a cylinder (301), a protection plate (302), a connecting rod (303), an inserting disc (304), a sliding block (305), a groove plate (306) and an elastic piece (307):
drum (301) and base (1) cup joint continuously, the outer wall rigid coupling of drum (301) has backplate (302), connecting rod (303) have been cup jointed to the inside of drum (301), the one end rigid coupling of connecting rod (303) has plug tray (304), the other end rigid coupling of connecting rod (303) has slider (305), the inner chamber rigid coupling of drum (301) has frid (306), elastic component (307) are installed to the outer wall of connecting rod (303), the one end and the plug tray (304) of elastic component (307) are laminated mutually, the other end and drum (301) of elastic component (307) are laminated mutually.
2. The apparatus for nucleic acid isolation and PCR amplification detection according to claim 1, wherein: slide rail (4) have been cup jointed to the outer wall of slider (305), slide rail (4) and base (1) fixed connection, bolt (5) have been cup jointed to the inside of slide rail (4), the outer wall of bolt (5) runs through slide rail (4) and links to each other with slider (305) screw thread, sealing plug (6) are installed to the one end that connecting rod (303) were kept away from in drum (301).
3. The apparatus for nucleic acid isolation and PCR amplification detection according to claim 1, wherein: an inner cavity of the base (1) is provided with a receiving assembly (7);
the containing assembly (7) comprises a containing box (701), a partition plate (702), a transverse plate (703) and a handle (704);
receiver (701) and base (1) cup joint continuously, the inside rigid coupling of receiver (701) has baffle (702), the one end rigid coupling that base (1) were kept away from in receiver (701) has diaphragm (703), one side rigid coupling that receiver (701) were kept away from in diaphragm (703) has handle (704).
4. The apparatus for nucleic acid isolation and PCR amplification detection according to claim 1, wherein: a fixing component (8) is arranged on the outer wall of the base (1);
the fixing component (8) comprises a fixing seat (801), a threaded rod (802) and a pressing plate (803);
fixing base (801) and base (1) fixed connection, the internally mounted of fixing base (801) has threaded rod (802), the outer wall rigid coupling of threaded rod (802) has clamp plate (803).
5. The apparatus for nucleic acid isolation and PCR amplification detection according to claim 1, wherein: the outer wall of the PCR instrument (2) is provided with a control panel (9), and the top of the PCR instrument (2) is provided with a top cover (10).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202220434003.6U CN216890920U (en) | 2022-03-01 | 2022-03-01 | Nucleic acid extraction and PCR amplification detection device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202220434003.6U CN216890920U (en) | 2022-03-01 | 2022-03-01 | Nucleic acid extraction and PCR amplification detection device |
Publications (1)
Publication Number | Publication Date |
---|---|
CN216890920U true CN216890920U (en) | 2022-07-05 |
Family
ID=82186820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202220434003.6U Active CN216890920U (en) | 2022-03-01 | 2022-03-01 | Nucleic acid extraction and PCR amplification detection device |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN216890920U (en) |
-
2022
- 2022-03-01 CN CN202220434003.6U patent/CN216890920U/en active Active
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5516490A (en) | Apparatus for preventing cross-contamination of multi-well test plates | |
JP4927074B2 (en) | Sample tube holder | |
CN1974016B (en) | Container with lid | |
EP2338597B1 (en) | Multiwell plate and lid | |
US7815863B2 (en) | Cartridge for containing a specimen sample for optical analysis | |
CN1049612C (en) | Array of reaction containers for an apparatus for automatic performance of temperature cycles | |
EP2338596B1 (en) | Tip rack | |
CN112538414A (en) | Full-sealed intelligent nucleic acid extraction device with micro-fluidic structure | |
EP2333560A2 (en) | Method for separating and detecting an analyte | |
EP2125214B1 (en) | Microplate kit | |
WO2009039039A1 (en) | Pipette tip ejection mechanism | |
MXPA03008081A (en) | Multi-well apparatus. | |
CN110494757B (en) | System and method for capacitive fluid level detection and handling of containers | |
CN216890920U (en) | Nucleic acid extraction and PCR amplification detection device | |
EP1255809B1 (en) | Method for closing and opening of an opening | |
EP1974818A1 (en) | Device and method for use in analysis | |
US20060115891A1 (en) | Apparatus for minimizing evaporation and/or condensation of samples occurring in tubes of multi-well plate mounted to PCR thermo cycler | |
US20010005490A1 (en) | Pipette for a pipette system | |
US20160161515A1 (en) | Form-locking gripping system | |
CN103874546A (en) | Positive-displacement pipette having an improved ejection function | |
GB2422795A (en) | Apparatus for processing biological sample | |
WO2017161058A1 (en) | Reaction vessel systems and methods and systems for using same | |
CN215517456U (en) | Nucleic acid extraction instrument | |
US20120087847A1 (en) | Filtering tube and microtube for the preparation and purification of small sample volumes | |
CN111361843A (en) | Blood collection box for clinical laboratory and constant temperature method |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A nucleic acid extraction and PCR amplification detection device Effective date of registration: 20230620 Granted publication date: 20220705 Pledgee: China Construction Bank Corporation Dalian Jinpu New Area Branch Pledgor: Dalian hehe medical laboratory Co.,Ltd. Registration number: Y2023980045050 |