CN216877481U - Powdered medicament inhaler - Google Patents
Powdered medicament inhaler Download PDFInfo
- Publication number
- CN216877481U CN216877481U CN202121394049.1U CN202121394049U CN216877481U CN 216877481 U CN216877481 U CN 216877481U CN 202121394049 U CN202121394049 U CN 202121394049U CN 216877481 U CN216877481 U CN 216877481U
- Authority
- CN
- China
- Prior art keywords
- capsule
- inhaler
- medicament
- airflow
- powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003814 drug Substances 0.000 title claims abstract description 44
- 239000002775 capsule Substances 0.000 claims abstract description 82
- 239000000843 powder Substances 0.000 claims abstract description 43
- 238000002156 mixing Methods 0.000 claims abstract description 28
- 238000003825 pressing Methods 0.000 claims description 12
- 229940079593 drug Drugs 0.000 claims description 2
- 210000000214 mouth Anatomy 0.000 abstract description 10
- 239000000203 mixture Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 4
- 239000000443 aerosol Substances 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000010276 construction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
Images
Landscapes
- Medicinal Preparation (AREA)
Abstract
The utility model discloses a powder medicament inhaler, which comprises a cyclone, a capsule cavity, an inhalation tube and a flaring tube; the cyclone is arranged at the air inlet of the capsule cavity and used for introducing airflow and forming rotary airflow; the lower end of the capsule cavity is connected with the suction pipe and is used for storing the punctured capsule and the medicament in the capsule is rotationally carried out and enters the suction pipe; the lower end of the suction pipe is connected with the flared pipe and is used for uniformly mixing the medicament and the airflow to enter the flared pipe; the outlet of the flared tube faces the patient's mouth for further uniform mixing of the medicament and the air flow and adjustment of the flow rate into the patient's mouth. The utility model can increase the rotation intensity of the airflow in the capsule cavity and the mixing function of the medicine, the airflow can be distributed more reasonably in the device, and the concentration of the medicine powder entering the oral cavity of a patient is more uniform.
Description
Technical Field
The utility model belongs to the technical field of medical instruments, and particularly relates to a powdered medicament inhaler.
Background
An oral inhalation formulation refers to a formulation that delivers a drug to the respiratory tract and/or lungs by the inhalation route for local or systemic action, primarily for the treatment of respiratory and other diseases. Clinically, the common oral inhalation preparation comprises an inhalation aerosol and an inhalation powder aerosol. In contrast to aerosols, inhalation powders are no longer dissolved using a propellant and are stored directly in capsules, blisters or reservoirs. When in use, the medicine powder enters the body by the self inspiration of the patient, thereby avoiding the problem of the matching of the breath and the external power.
Inhalation of the dry powder inhalation needs to be performed by drug delivery devices (inhalation devices), currently representative of which include the (blister type) of GlaxoSmithKline, the (reservoir type) of AstraZeneca and the (capsule type) of Boringer Varghagan Boehringer Ingelheim.
The requirements for the performance of the inhaler are that the utilization rate of the medicinal powder is high and the medicament in the capsule plays a full role. This first requires that all of the powder be expelled from the capsule into the inhaler chamber and inhaled by the patient, while at the same time requiring that the powder be uniformly mixed and enter the body at a uniform and appropriate rate.
SUMMERY OF THE UTILITY MODEL
In view of the above, the main object of the present invention is to provide a powdered medicament inhaler.
In order to achieve the purpose, the technical scheme of the utility model is realized as follows:
the embodiment of the utility model provides a powder medicament inhaler, which comprises a cyclone, a capsule cavity, an inhalation tube and a flaring tube;
the cyclone is arranged at the air inlet of the capsule cavity and used for introducing airflow and forming rotary airflow;
the lower end of the capsule cavity is connected with the suction pipe and is used for storing the punctured capsule and the medicament in the capsule is rotationally carried out and enters the suction pipe;
the lower end of the suction pipe is connected with the flared pipe and is used for uniformly mixing the medicament and the airflow to enter the flared pipe;
the outlet of the flared tube faces the patient's mouth for further uniform mixing of the medicament and the air flow and adjustment of the flow rate into the patient's mouth.
In the above scheme, the cyclone comprises a spiral shell and an inner cylinder, the spiral shell is sleeved outside the inner cylinder, an air inlet is formed in the side surface of the spiral shell, and the spiral shell is arranged at the top end of the capsule cavity and communicated with the capsule cavity.
In the above scheme, the suction pipe is also internally provided with a mixing blade for uniformly mixing the airflow and the medicinal powder.
In the above scheme, the mixing blade adopts at least one group of staggered helical blades or one internal helical blade.
In the above scheme, the capsule puncture mechanism is further included and arranged on one side of the capsule cavity and used for puncturing capsules stored in the capsule cavity.
In the above scheme, the capsule puncturing mechanism comprises a pressing shell, a flexible support, an upper puncturing needle, a lower puncturing needle, a mounting plate and a return spring, wherein the mounting plate is fixed on the outer side of the capsule cavity, the left side and the right side of the pressing shell are respectively arranged on the mounting plate through the flexible support, the return spring is arranged between the mounting plate and the pressing shell, the upper puncturing needle and the lower puncturing needle are respectively arranged on the upper side and the lower side of the pressing shell, and the end parts of the upper puncturing needle and the lower puncturing needle penetrate through the mounting plate and through holes correspondingly arranged in the capsule cavity.
In the above scheme, a buffer chamber is further arranged between the capsule cavity and the suction pipe, and the buffer chamber is used for mixing air and the medicinal powder in the capsule.
Compared with the prior art, the utility model can increase the rotation intensity of the airflow in the capsule cavity and the mixing function of the medicine, the airflow can be distributed more reasonably in the device, and the concentration of the medicine powder entering the oral cavity of a patient is more uniform.
Drawings
The accompanying drawings, which are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiment(s) of the utility model and together with the description serve to explain the utility model without limiting the utility model. In the drawings:
FIG. 1 is a schematic diagram of a powder medicament inhaler according to an embodiment of the present invention;
FIG. 2 is a schematic view of a cyclone in a powdered medicament inhaler according to an embodiment of the present invention;
FIG. 3 is a schematic diagram of a mixing blade of a powdered medicament inhaler according to an embodiment of the present invention;
FIG. 4 is another schematic view of a mixing blade of a powdered medicament inhaler according to an embodiment of the present invention;
FIG. 5 is an air flow profile of an inhaler of prior art construction;
FIG. 6 is a gas flow profile of the present invention;
fig. 7 is a diagram showing a distribution of powder in an inhaler of a conventional structure;
figure 8 is a graph of the powder distribution of the present invention;
FIG. 9 is an air flow profile of a long flared shape inhaler of prior art construction;
FIG. 10 is a gas flow profile at the flared tube of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the utility model and are not intended to limit the utility model.
The same or similar reference numerals in the drawings of the present embodiment correspond to the same or similar components; in the description of the present invention, it is to be understood that the terms "upper", "lower", "left", "right", "inner", "outer", etc. indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the referred devices or elements must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, the terms describing the positional relationships in the drawings are only for illustrative purposes and are not to be construed as limitations of the present patent, and specific meanings of the terms may be understood by those skilled in the art according to specific situations.
It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other like elements in a process, article, or apparatus that comprises the element.
The embodiment of the utility model provides a powder medicament inhaler, which is shown in figure 1 and comprises a cyclone 1, a capsule cavity 2, an inhalation tube 3 and a flared tube 4;
the cyclone 1 is arranged at the air inlet of the capsule cavity 2 and used for introducing airflow and forming rotary airflow;
the lower end of the capsule cavity 2 is connected with an inhalation tube 3 and is used for storing punctured capsules and the medicament in the capsules is taken out into the inhalation tube 3 by rotation;
the lower end of the suction pipe 3 is connected with a flared pipe 4 and is used for uniformly mixing the medicament and the air flow and entering the flared pipe 4;
the outlet of the flared tube 4 faces the patient's mouth for further mixing the medicament and the air flow evenly and adjusting the flow rate into the patient's mouth.
As shown in FIG. 2, the cyclone 1 comprises a spiral shell 11 and an inner cylinder 12, the spiral shell 11 is sleeved outside the inner cylinder 12, an air inlet 13 is arranged at the side surface of the spiral shell 11, and the spiral shells 11 are arranged at the top end of the capsule cavity 2 and are communicated with each other.
The inner cylinder 12, the spiral shell 11 and the capsule cavity 2 can be of an integral structure or a split structure and then are connected together; said inner cylinder 12 bears from the upper side against the capsule in the capsule chamber 2, securing it for subsequent piercing.
The suction pipe 3 is also provided with a mixing blade 31 for uniformly mixing the airflow and the medicinal powder. .
Further, as shown in fig. 3, the mixing blade 31 employs at least one set of helical blades arranged in a staggered manner, or as shown in fig. 4, the mixing blade 31 employs an inner helical blade.
Further, the capsule puncturing device comprises a capsule puncturing mechanism 5, wherein the capsule puncturing mechanism 5 is arranged on one side of the capsule cavity 2 and is used for puncturing capsules stored in the capsule cavity 2.
The capsule puncturing mechanism 5 comprises a pressing shell 51, a flexible supporting piece 52, an upper puncturing needle 53, a lower puncturing needle 54, a mounting plate 55 and a return spring 56, wherein the mounting plate 55 is fixed on the outer side of the capsule cavity 2, the left side and the right side of the pressing shell 51 are respectively arranged on the mounting plate 55 through the flexible supporting piece 52, the return spring 56 is arranged between the mounting plate 55 and the pressing shell 51, the upper puncturing needle 53 and the lower puncturing needle 54 are respectively arranged on the upper side and the lower side of the pressing shell 51, and the end parts of the upper puncturing needle 53 and the lower puncturing needle 54 penetrate through holes correspondingly arranged on the mounting plate 55 and the capsule cavity 2.
A buffer chamber 6 is also arranged between the capsule cavity 2 and the suction pipe 3, and the buffer chamber 6 is used for mixing air and the medicine powder in the capsule.
The capsule placed in the capsule cavity 2 is pierced with a small hole by an upper piercing needle 53 and a lower piercing needle 54 of a capsule piercing mechanism 5 respectively at the upper part and the lower part of the capsule, the pierced capsule is driven by rotary airflow to rotate rapidly in the capsule cavity 2, the medicine powder in the capsule is thrown from the rapidly rotating capsule and is mixed with the rotary airflow, the air and the medicine powder mixture are continuously mixed in a buffer 6, the air and the medicine powder mixture from the buffer chamber 6 enter an intake pipe 3 and are fully mixed under the stirring of an inner spiral sheet, and finally the air and the medicine powder mixture enter the oral cavity from a flaring pipe 4.
The working process of the utility model is as follows:
the airflow enters from the inlet of the cyclone 1, rotates downwards in the capsule cavity 2 and drives the punctured capsule to rotate, the medicine powder in the capsule is thrown out from the broken opening, the medicine powder thrown out from the capsule and the airflow are mixed in the buffer chamber 6 and then enter the suction pipe 3, the medicine powder and the airflow entering the suction pipe 3 are further mixed under the action of the guide vanes, and the mixture of the medicine powder and the airflow enters the flared pipe 4 and finally enters the cavity.
The flared tube 4 on the one hand allows to regulate the flow rate of the gas-powder mixture entering the oral cavity and at the same time has an effect on the further mixing of the powder.
As shown in fig. 5, air enters the inhaler of the prior art from the upper circular tube of the inhaler, suddenly expands at the junction of the capsule and the upper suction tube and blows toward the capsule. The air flow then flows down the gap between the capsule and the capsule cavity, where it can be seen that the air flow is from top to bottom and the air does not rotate.
As shown in fig. 6, the air from the cyclone enters the inhaler and then rotates into the capsule cavity without sudden expansion between the capsule cavity and the cyclone, and the air flow then rotates and flows downwards along the gap between the capsule and the capsule cavity, and the downward rotating air flow facilitates the mixing of the medicinal powder.
It can also be seen that at the lower flared portion of the inhaler, the airflow rate of the whirlwind inhaler is more uniform than the airflow rate of the whirlwind inhaler.
As shown in fig. 7, it can be seen that in the inhaler of the prior art, the powder is concentrated in the central portion of the flaring of the inhaler, and the distribution of the flaring of the powder is not uniform. In fig. 7, the light color area is the area where the powder appears.
As shown in fig. 8, it can be seen that the powder is concentrated in the inhaler and dispersed, and the distribution of the powder flare is uniform. In fig. 8, the light color area is the area where the powder appears.
As shown in fig. 9, it can be seen that in the short flared shape inhaler of the present invention, the concentration profile at the inhaler exit becomes no longer uniform. In fig. 9, the light color area is the area where the powder appears.
As shown in fig. 10, it can be seen that further lengthening the suction flare length within the present invention has little effect on the uniformity of the concentration profile, and thus it can be seen that a medium length flare length is optimal when the mixing vanes are placed on top of the suction tube. In fig. 10, light areas are areas where the powder appears.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention.
Claims (7)
1. A powder medicament inhaler is characterized by comprising a cyclone, a capsule cavity, an inhalation tube and a flaring tube;
the cyclone is arranged at the air inlet of the capsule cavity and used for introducing airflow and forming rotary airflow;
the lower end of the capsule cavity is connected with the suction pipe and is used for storing the punctured capsule and the medicament in the capsule is rotationally carried out and enters the suction pipe;
the lower end of the suction pipe is connected with the flared pipe and is used for uniformly mixing the medicament and the airflow to enter the flared pipe;
the outlet of the flared tube faces the patient's mouth for further uniform mixing of the medicament and the air flow and adjustment of the flow rate into the patient's mouth.
2. The inhaler for powdered medicaments as claimed in claim 1, wherein said cyclone comprises a spiral housing, an inner cylinder, the spiral housing is sleeved outside the inner cylinder, the side of the spiral housing is provided with an air inlet, and the spiral housings are arranged at the top end of the capsule cavity and are communicated with each other.
3. The inhaler of claim 1 or 2, wherein a mixing blade is further provided in said inhalation tube for uniformly mixing the air stream and the drug powder.
4. The powder medicament inhaler of claim 3, wherein the mixing blade comprises at least one set of staggered helical blades or an internal helical blade.
5. The powder dose inhaler of claim 4, further comprising a capsule puncturing mechanism disposed on a side of the capsule chamber for puncturing a capsule stored in the capsule chamber.
6. The inhaler for powdered medicaments according to claim 5, wherein the capsule puncturing mechanism comprises a pressing housing, a flexible supporting member, an upper puncturing needle, a lower puncturing needle, a mounting plate and a return spring, the mounting plate is fixed outside the capsule cavity, the left side and the right side of the pressing housing are respectively arranged on the mounting plate through the flexible supporting member, the return spring is arranged between the mounting plate and the pressing housing, the upper puncturing needle and the lower puncturing needle are respectively arranged on the upper side and the lower side of the pressing housing, and the end parts of the upper puncturing needle and the lower puncturing needle penetrate through holes correspondingly arranged in the mounting plate and the capsule cavity.
7. The inhaler of claim 6, wherein a buffer chamber is further provided between the capsule chamber and the inhalation tube for mixing air with the powder in the capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121394049.1U CN216877481U (en) | 2021-06-23 | 2021-06-23 | Powdered medicament inhaler |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202121394049.1U CN216877481U (en) | 2021-06-23 | 2021-06-23 | Powdered medicament inhaler |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216877481U true CN216877481U (en) | 2022-07-05 |
Family
ID=82178885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202121394049.1U Active CN216877481U (en) | 2021-06-23 | 2021-06-23 | Powdered medicament inhaler |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216877481U (en) |
-
2021
- 2021-06-23 CN CN202121394049.1U patent/CN216877481U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US8297278B2 (en) | Dry powder inhaler | |
| JP3706136B2 (en) | Apparatus and method for dispersing dry powder drug | |
| JP2912453B2 (en) | Dry powder inhaler | |
| RU2136322C1 (en) | Inhaler for dry powder | |
| US6766799B2 (en) | Inhalation device | |
| ES2256293T3 (en) | INHALERS. | |
| CN207666946U (en) | A kind of capsule-type medicinal powder inhaler | |
| US20080251072A1 (en) | Inhaler Device | |
| TW200950836A (en) | Inhaler | |
| JPH09504455A (en) | Dry powder drug inhaler | |
| AU2002255808A1 (en) | Inhalation device and method | |
| WO2019101135A1 (en) | Novel dry powder inhalation device | |
| CN110812635A (en) | Administration device for inhaling powder inhalation | |
| WO2019101136A1 (en) | Powder release device and method | |
| CN216877481U (en) | Powdered medicament inhaler | |
| WO2011080761A1 (en) | An improved dry powder inhaler | |
| CN105920709B (en) | The Po Nang mechanism of powder spray drug delivery device | |
| CN113244491A (en) | Inhaler for powdered medicaments | |
| CN106075676B (en) | Administration mechanism of dry powder inhalation device | |
| WO2024044257A1 (en) | Air-jet dry powder inhaler (dpi) with passive cyclic loading of the formulation | |
| MXPA96004768A (en) | Dust inhaler s |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A powder drug inhaler Granted publication date: 20220705 Pledgee: Chengdong Branch of Nanjing Bank Co.,Ltd. Pledgor: Nanjing Licheng Pharmaceutical Co.,Ltd. Registration number: Y2024980012282 |
|
| PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
| PC01 | Cancellation of the registration of the contract for pledge of patent right |
Granted publication date: 20220705 Pledgee: Chengdong Branch of Nanjing Bank Co.,Ltd. Pledgor: Nanjing Licheng Pharmaceutical Co.,Ltd. Registration number: Y2024980012282 |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A powdered drug inhaler Granted publication date: 20220705 Pledgee: Chengdong Branch of Nanjing Bank Co.,Ltd. Pledgor: Nanjing Licheng Pharmaceutical Co.,Ltd. Registration number: Y2024980038120 |