CN216808804U

CN216808804U - Cell inoculation device

Info

Publication number: CN216808804U
Application number: CN202122739440.7U
Authority: CN
Inventors: 舒军; 蔡挺; 潘晗
Original assignee: Shanghai Celgen Biopharma Co ltd
Current assignee: Shanghai Celgen Biopharma Co ltd
Priority date: 2021-11-10
Filing date: 2021-11-10
Publication date: 2022-06-24
Anticipated expiration: 2031-11-10

Abstract

The utility model discloses a cell inoculation device, comprising: the device comprises a supporting table and supporting columns, wherein the supporting columns are arranged at four corners of the bottom of the supporting table, a clamping rotating structure is arranged on the supporting table, and an inoculator is arranged between the clamping rotating structure and the supporting table; the utility model relates to the technical field of cell inoculation, and the inoculator can be clamped and fixed through a clamping and rotating structure and then rotated, so that cells in the inoculator can be uniformly distributed in the inoculator, the phenomenon of contact inhibition during cell inoculation is prevented, and the inoculator is convenient to disassemble and replace.

Description

Cell inoculation device

Technical Field

The utility model relates to the technical field of cell inoculation, in particular to a cell inoculation device.

Background

Cell culture refers to all in vitro culture, and means that a tissue is taken out from an animal or human body, the tissue is separated into single cells by a mechanical method or an enzymatic digestion method, and the single cells are incubated and cultured under specific in vitro conditions such as a simulated in vivo physiological environment to survive and grow. In order to make the cells grow smoothly, it is often necessary to detect the growth environment of the cells during the cell culture process.

In the prior art, the scheme of inoculating the cells into the reactor is that the inoculated cells are conveyed through a pipeline, so the cells are often gathered together when being inoculated into the cell reactor. Thus, contact inhibition often occurs when cells come into contact with each other during the subsequent cell culture process. Contact inhibition refers to the phenomenon in which when cells of a multicellular organism are cultured in vitro, the cells growing dispersedly adherent to each other come together and contact with each other, and then stop moving and growing. Once the cell contact inhibition phenomenon occurs, the yield and effect of cell culture are greatly influenced.

SUMMERY OF THE UTILITY MODEL

Aiming at the defects of the prior art, the utility model provides a cell inoculation device, which solves the problem that cells are often gathered together when being inoculated in a cell reactor because the inoculated cells are conveyed through a pipeline in the prior art. Thus, the contact inhibition phenomenon often occurs when the cells contact each other in the subsequent cell culture process.

In order to realize the purpose, the utility model is realized by the following technical scheme: a cell seeding device comprising: the device comprises a supporting table and supporting columns, wherein the supporting columns are arranged at four corners of the bottom of the supporting table, a clamping rotating structure is arranged on the supporting table, and an inoculator is arranged between the clamping rotating structure and the supporting table;

the clamping rotation structure includes: the device comprises a first motor, a first rotating shaft, a lower rotating plate, a lifting assembly, a pressing plate, a second rotating shaft and an upper rotating plate;

the first motor sets up the bottom of brace table, the output fixed connection of first pivot and first motor, lower swivel plate sets up in the first pivot, lifting unit sets up inside the right side of brace table, the pressure strip sets up lifting unit is last, the second pivot is rotated and is connected the bottom of pressure strip, it is in to go up the swivel plate setting in the second pivot.

Preferably, the lifting assembly comprises: the screw rod, the second motor and the slide rail;

the lead screw swing joint be in inside the right side of brace table, the second motor sets up the right side top of brace table, the output of second motor with lead screw fixed connection, the slide rail sets up inside the right side of brace table, the pressure strip suit is in on the lead screw and with slide rail sliding connection.

Preferably, the upper rotating plate and the lower rotating plate are both provided with clamping grooves, and the clamping grooves are both provided with clamping blocks.

Preferably, the top surface of the fixture block is hexagonal.

Preferably, a controller is arranged at the front end of the right side of the support platform.

Preferably, the diameter of the radial section of the inoculator is equal to the diameter of the clamping groove.

Compared with the prior art, the utility model has the beneficial effects that:

this cell inoculation device, the present case designs inner structure simply, can press from both sides the tight fixed to the inoculator through the tight revolution mechanic that presss from both sides that is equipped with, then rotates the inoculator to make the distribution that the cell in the inoculator can be even in the inside of inoculator, the phenomenon of contact suppression appears when preventing the cell inoculation, and the dismantlement of the inoculator of also being convenient for is changed.

Drawings

FIG. 1 is a schematic sectional view of a cell seeding apparatus according to the present invention.

FIG. 2 is a schematic front view of a cell seeding apparatus according to the present invention.

FIG. 3 is a schematic top view of a clamping groove of the cell seeding apparatus according to the present invention.

In the figure: 1. a support table; 2. a support column; 3. an inoculator; 4. a first motor; 5. a first rotating shaft; 6. a lower rotating plate; 7. a compression plate; 8. a second rotating shaft; 9. an upper spin plate; 10. a screw rod; 11. a second motor; 12. a slide rail; 13. a clamping groove; 14. a clamping block; 15. and a controller.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-3, the present invention provides a technical solution: a cell seeding device comprising: the device comprises a supporting table 1 and supporting columns 2, wherein the supporting columns 2 are arranged at four corners of the bottom of the supporting table 1, a clamping rotating structure is arranged on the supporting table 1, and an inoculator 3 is arranged between the clamping rotating structure and the supporting table 1; brace table 1 is used for supporting the equipment part that is located it, support column 2 is used for supporting fixed brace table 1, can press from both sides tight fixedly to inoculator 3 through the tight revolution mechanic that presss from both sides that is equipped with, then rotate inoculator 3, thereby make the inside of distribution that the cell in inoculator 3 can be even at inoculator 3, prevent that the cell inoculation is the phenomenon that contact inhibition appears, and the dismantlement of the inoculator 3 of also being convenient for is changed, inoculator 3 is used for carrying out the cultivation inoculation of cell, press from both sides tight revolution mechanic, contain: the device comprises a first motor 4, a first rotating shaft 5, a lower rotating plate 6, a lifting assembly, a pressing plate 7, a second rotating shaft 8 and an upper rotating plate 9; the first motor 4 is arranged at the bottom of the supporting table 1, the first rotating shaft 5 is fixedly connected with the output end of the first motor 4, the lower rotating plate 6 is arranged on the first rotating shaft 5, the lifting assembly is arranged inside the right side of the supporting table 1, the pressing plate 7 is arranged on the lifting assembly, the second rotating shaft 8 is rotatably connected to the bottom of the pressing plate 7, and the upper rotating plate 9 is arranged on the second rotating shaft 8;

first motor 4 is used for providing power, and first motor 4 operation can drive 5 rotations of first pivot, and lower swivel plate 6 rotates, and then drives inoculator 3 that is located on lower swivel plate 6 and rotates, and lifting unit can control the pressure strip 7 and compress tightly downwards to make upper swivel plate 9 carry out the chucking to inoculator 3, second pivot 8 is used for letting upper swivel plate 9 rotate on pressure strip 7, and lifting unit contains: the screw rod 10 is movably connected inside the right side of the support table 1, the second motor 11 is arranged above the right side of the support table 1, the output end of the second motor 11 is fixedly connected with the screw rod 10, the slide rail 12 is arranged inside the right side of the support table 1, and the pressing plate 7 is sleeved on the screw rod 10 and is in sliding connection with the slide rail 12; rotate through second motor 11, can drive lead screw 10 and rotate, and then pinch plate 7 carries out the up-and-down motion, slide rail 12 is used for playing the effect of direction, all be equipped with on last rotor plate 9 and the lower rotor plate 6 and press from both sides tight groove 13, all be equipped with fixture block 14 on pressing from both sides tight groove 13, press from both sides tight groove 13 and be used for playing fine tight effect of clamp, fixture block 14 is used for carrying out the joint to inoculator 3, thereby guarantee to drive inoculator 3 and rotate, the top surface of fixture block 14 is the hexagon, can guarantee the joint effect, be convenient for let inoculator 3 rotate, the right side front end of brace table 1 is equipped with controller 15, controller 15 is used for carrying out the control of equipment, the radial cross-section diameter of inoculator 3 equals with the diameter size that presss from both sides tight groove 13, be convenient for let inoculator 3 joint press from both sides tight groove 13, guarantee the tight effect of clamp.

The working principle is as follows: put inoculator 3 into down on the fixture block 14 on the rotating plate 6 earlier, and the joint is on the tight groove 13 of clamp on lower rotating plate 6, then control second motor 11 through controller 15 and rotate and can drive lead screw 10 and rotate, and then pinch plate 7 carries out decurrent motion, thereby make upper rotating plate 9 carry out the chucking to inoculator 3, let the tight groove 13 of clamp on the upper rotating plate 9 carry out the joint with inoculator 3, then first motor 4 operation can drive first pivot 5 and rotate, lower rotating plate 6 rotates, and then drive the inoculator 3 that is located lower rotating plate 6 and rotate, make the cell evenly distributed in inoculator 3, prevent contact inhibition.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation. The use of the phrase "comprising one of the elements does not exclude the presence of other like elements in the process, method, article, or apparatus that comprises the element.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A cell seeding device comprising: the device comprises a supporting table (1) and supporting columns (2), and is characterized in that the supporting columns (2) are arranged at four corners of the bottom of the supporting table (1), a clamping rotating structure is arranged on the supporting table (1), and a inoculator (3) is arranged between the clamping rotating structure and the supporting table (1);

the clamping rotation structure includes: the device comprises a first motor (4), a first rotating shaft (5), a lower rotating plate (6), a lifting assembly, a pressing plate (7), a second rotating shaft (8) and an upper rotating plate (9);

first motor (4) set up the bottom of brace table (1), the output fixed connection of first pivot (5) and first motor (4), lower swivel plate (6) set up on first pivot (5), lifting unit sets up inside the right side of brace table (1), pressure strip (7) set up on the lifting unit, second pivot (8) rotate to be connected the bottom of pressure strip (7), go up swivel plate (9) set up on second pivot (8).

2. A cell seeding apparatus according to claim 1, wherein: the lifting assembly comprises: the screw rod (10), the second motor (11) and the slide rail (12);

lead screw (10) swing joint be in inside the right side of brace table (1), second motor (11) set up the right side top of brace table (1), the output of second motor (11) with lead screw (10) fixed connection, slide rail (12) set up inside the right side of brace table (1), pressure strip (7) suit is in on lead screw (10) and with slide rail (12) sliding connection.

3. A cell seeding apparatus according to claim 1, wherein: the upper rotating plate (9) and the lower rotating plate (6) are respectively provided with a clamping groove (13), and the clamping grooves (13) are respectively provided with a clamping block (14).

4. A cell seeding apparatus according to claim 3 wherein: the top surface of the fixture block (14) is hexagonal.

5. A cell seeding apparatus according to claim 1, wherein: the front end of the right side of the support table (1) is provided with a controller (15).

6. A cell seeding apparatus according to claim 3, wherein: the diameter of the radial section of the inoculator (3) is equal to the diameter of the clamping groove (13).