CN216771678U - Efficient automatic release rate sampling system - Google Patents

Efficient automatic release rate sampling system Download PDF

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Publication number
CN216771678U
CN216771678U CN202123300991.XU CN202123300991U CN216771678U CN 216771678 U CN216771678 U CN 216771678U CN 202123300991 U CN202123300991 U CN 202123300991U CN 216771678 U CN216771678 U CN 216771678U
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China
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fixedly connected
release rate
power box
telescopic rod
rotating
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CN202123300991.XU
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Chinese (zh)
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蔺孟瑶
林红杰
傅秀秀
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SHANDONG CHUANGXIN PHARMACEUTICAL RESEARCH AND DEVELOPMENT CO LTD
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SHANDONG CHUANGXIN PHARMACEUTICAL RESEARCH AND DEVELOPMENT CO LTD
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Abstract

The utility model discloses an efficient automatic release rate sampling system, and belongs to the technical field of drug release rate testing. An efficient automatic release rate sampling system, comprising a reciprocating power box, further comprising: the rotating power box is fixedly connected to the reciprocating power box, and a rotating rod is rotatably connected to the rotating power box; the telescopic rod is connected to the rotating rod in a sliding mode, a sliding groove corresponding to the rotating rod is formed in the telescopic rod, and two limiting rings are fixedly connected to the telescopic rod; the connecting plate is connected to the reciprocating power box in a sliding mode, a lantern ring is fixedly connected to the connecting plate, and the lantern ring is sleeved on the telescopic rod; the utility model can drive the telescopic rod to reciprocate on the rotating rod or the telescopic rod to rotate under the driving of the rotating rod through the matching of the second motor and the first motor, and then the telescopic rod is respectively matched with the corresponding stirring components, so that the test of two release rate methods can be carried out on the medicine, the test methods are various, and the test of the release rate of the medicine is convenient.

Description

Efficient automatic release rate sampling system
Technical Field
The utility model relates to the technical field of drug release rate testing, in particular to an efficient automatic release rate sampling system.
Background
In order to test the release rate of the medicine in vivo, a multi-purpose dissolution instrument on the market performs simulation test of the release rate of the medicine.
The drug release rate is mostly tested by a reciprocating bracket method or a paddle-and-dish method, while the existing dissolution instrument can only test a single method and cannot test two methods for the drug, and the test method is single and has poor experimental effect.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the problem that a method for testing the drug release rate of a dissolution instrument in the prior art is single, and provides an efficient automatic release rate sampling system.
In order to achieve the purpose, the utility model adopts the following technical scheme:
an efficient automatic release rate sampling system, comprising a reciprocating power box, further comprising: the rotating power box is fixedly connected to the reciprocating power box, and a rotating rod is rotatably connected to the rotating power box; the telescopic rod is connected to the rotating rod in a sliding mode, a sliding groove corresponding to the rotating rod is formed in the telescopic rod, and two limiting rings are fixedly connected to the telescopic rod; the connecting plate is connected to the reciprocating power box in a sliding mode, a lantern ring is fixedly connected to the connecting plate, the lantern ring is sleeved on the telescopic rod, and the lantern ring is located between the two limiting rings; the stirring component is detachably connected to one end of the telescopic rod and is used for accelerating the dissolution of the medicine; the water bath tank is fixedly connected to the reciprocating power box, the dissolving cup is fixedly connected to the water bath tank, the dissolving cup corresponds to the stirring assembly, and the heating block is fixedly connected to the bottom of the water bath tank.
In order to facilitate testing of multiple groups of medicines simultaneously, preferably, the rotating rod is provided with four groups, the top end of the rotating rod extends into the rotating power box and is fixedly connected with gears, and the gears are connected in a rotating mode through timing belts.
In order to facilitate the rotation of the driving rotating rod, further, a first motor is fixedly connected to the rotating power box, and the output end of the first motor is fixedly connected with the center of the gear.
In order to facilitate the reciprocating sliding of the driving telescopic rod on the rotating rod, preferably, a second motor is fixedly connected in the reciprocating power box, a reciprocating screw rod is fixedly connected at the output end of the second motor, a reciprocating plate is connected to the reciprocating screw rod in a threaded manner, and one end, far away from the lantern ring, of the connecting plate is fixedly connected with the reciprocating plate.
In order to facilitate the drug testing by using the stirring method, preferably, the stirring assembly comprises a stirring paddle, and the stirring paddle is in threaded connection with the telescopic rod.
In order to facilitate the drug testing by using the reciprocating support method, preferably, the stirring assembly comprises a placing frame, and the placing frame is in threaded connection with the telescopic rod.
Compared with the prior art, the utility model provides an efficient automatic release rate sampling system, which has the following beneficial effects:
1. this automatic release rate sampling system of efficient heats to required temperature and keeps warm through the water of heating piece in to the water bath to carry out water bath heating to required temperature, the internal stable environment of simulation in the experimentation of being convenient for to four solutions that dissolve the cup.
2. This automatic release rate sampling system of efficient rotates through first motor drive dwang to the drive telescopic link drives the stirring rake and at dissolving the cup internal rotation, in order to reach the purpose that uses the oar dish method to test the medicine release rate.
3. This automatic release rate sampling system of efficient through the reciprocal slip of second motor drive reciprocating plate on reciprocal lead screw to drive telescopic link reciprocal transportation on the dwang, thereby carry out reciprocal the soaking in the solution of different dissolving cups to the medicine on the rack of telescopic link bottom, thereby carry out the release rate test of medicine through reciprocal support method.
The parts which are not involved in the device are the same as or can be realized by adopting the prior art, the device can drive the telescopic rod to do reciprocating motion on the rotating rod or the telescopic rod to do autorotation motion under the driving of the rotating rod through the matching of the second motor and the first motor, and then the telescopic rod is respectively matched with the corresponding stirring assemblies, so that the drug can be tested by two release rate methods, the test methods are various, and the test of the release rate of the drug is convenient.
Drawings
FIG. 1 is a front view of a high efficiency automatic release rate sampling system according to the present invention;
FIG. 2 is a right side view of an efficient automatic release rate sampling system according to the present invention;
fig. 3 is a schematic structural view of a telescopic rod of an efficient automatic release rate sampling system according to the present invention.
In the figure: 1. a reciprocating power box; 2. a water bath tank; 21. a dissolving cup; 22. a heating block; 3. rotating the power box; 4. a first motor; 41. rotating the rod; 42. a timing belt; 43. a gear; 5. a telescopic rod; 51. a limiting ring; 52. a chute; 6. a stirring paddle; 61. placing a rack; 7. a second motor; 71. a reciprocating screw rod; 8. a connecting plate; 81. a collar; 82. a reciprocating plate.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
Example (b):
referring to fig. 1-3, an efficient automatic release rate sampling system includes a reciprocating power box 1, further including: the rotating power box 3 is fixedly connected to the reciprocating power box 1, and a rotating rod 41 is rotatably connected to the rotating power box 3; the telescopic rod 5 is connected to the rotating rod 41 in a sliding manner, a sliding groove 52 corresponding to the rotating rod 41 is formed in the telescopic rod 5, and two limiting rings 51 are fixedly connected to the telescopic rod 5; the connecting plate 8 is connected to the reciprocating power box 1 in a sliding manner, a lantern ring 81 is fixedly connected to the connecting plate 8, the lantern ring 81 is sleeved on the telescopic rod 5, and the lantern ring 81 is located between the two limiting rings 51; the stirring component is detachably connected to one end of the telescopic rod 5 and is used for accelerating the dissolution of the medicine; the water bath box 2 is fixedly connected to the reciprocating power box 1, the dissolving cup 21 is fixedly connected to the water bath box 2, the dissolving cup 21 corresponds to the stirring component, and the heating block 22 is fixedly connected to the bottom of the water bath box 2.
Dwang 41 is equipped with four groups, and dwang 41 top extends to and rotates in the headstock 3 and fixedly connected with gear 43, and four gears 43 rotate through timing belt 42 and connect, rotate the first motor 4 of fixedly connected with on the headstock 3, first motor 4 output and gear 43 center fixed connection.
The second motor 7 is fixedly connected in the reciprocating power box 1, the output end of the second motor 7 is fixedly connected with a reciprocating screw rod 71, a reciprocating plate 82 is connected to the reciprocating screw rod 71 in a threaded mode, and one end, far away from the lantern ring 81, of the connecting plate 8 is fixedly connected with the reciprocating plate 82.
In the using process of the device, when the paddle-disc method is needed to test the release rate of the medicine, the heating block 22 is started to heat the water in the water bath box 2 to the specified temperature and keep the temperature, the four dissolving cups 21 in the water bath box 2 are respectively poured with the solution simulating the body fluid in different organs in vivo, then the medicine is respectively placed in the four dissolving cups 21, the second motor 7 is controlled to be started to drive the reciprocating screw rod 71 to rotate, so as to drive the reciprocating plate 82 in threaded connection with the reciprocating screw rod 71 to slide downwards, thus the four lantern rings 81 synchronously move downwards under the linkage of the four connecting plates 8, so as to drive one ends of the four telescopic rods 5 provided with the stirring components to be immersed in the corresponding dissolving cups 21, then the first motor 4 is started, the first motor 4 drives the gear 43 to rotate, the four gears 43 synchronously rotate under the linkage of the timing belt 42, so as to drive the four rotating rods 41 to synchronously rotate, and dwang 41 is the quadrangular appearance and sliding connection in the spout 52 of telescopic link 5, so dwang 41 rotates the in-process and can drive telescopic link 5 and roll out to the stirring subassembly that the messenger immerges four dissolving cups 21 rotates in step, so can use the oar dish method to test the release rate of medicine through this equipment.
When needing to use the reciprocal support method to carry out the release rate test to the medicine, can repeat above-mentioned heating and pour the step back of solution into, on the medicine that will need the test is fixed respectively places stirring subassembly on four telescopic links 5, then only starts second motor 7, through the reciprocal motion of second motor 7 drive telescopic link 5 on dwang 41 to can use the reciprocal support method to test the release rate of medicine through this equipment.
Stirring subassembly includes stirring rake 6, and 6 threaded connection of stirring rake on telescopic link 5, when needs use the stirring method to test the medicine release rate, can be with 6 threaded mounting of stirring rake to the bottom of telescopic link 5 on, the use oar dish method of being convenient for carries out the medicine release rate test.
Stirring subassembly includes rack 61, and rack 61 threaded connection is on telescopic link 5, when needs use reciprocal support method test medicine release rate, can fix the placing to the medicine that needs the test on the bottom of telescopic link 5 with rack 61 threaded mounting, is convenient for to carry out the release rate test through reciprocal support method.
This device can be through the cooperation of second motor 7 and first motor 4 to drive telescopic link 5 reciprocating motion or telescopic link 5 rotation motion under the dwang 41 drive on dwang 41, the rethread respectively with the stirring subassembly cooperation that corresponds, so can carry out the test of two kinds of release rate methods to the medicine, test method is various, is convenient for test the release rate of medicine.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.

Claims (6)

1. An efficient automatic release rate sampling system comprising a reciprocating power box (1), characterized by further comprising:
the rotating power box (3) is fixedly connected to the reciprocating power box (1), and a rotating rod (41) is rotatably connected to the rotating power box (3);
the telescopic rod (5) is connected to the rotating rod (41) in a sliding mode, a sliding groove (52) corresponding to the rotating rod (41) is formed in the telescopic rod (5), and two limiting rings (51) are fixedly connected to the telescopic rod (5);
the connecting plate (8) is connected to the reciprocating power box (1) in a sliding mode, a lantern ring (81) is fixedly connected to the connecting plate (8), the lantern ring (81) is sleeved on the telescopic rod (5), and the lantern ring (81) is located between the two limiting rings (51);
the stirring component is detachably connected to one end of the telescopic rod (5) and is used for accelerating the dissolution of the medicine;
the water bath device is characterized in that the water bath device is fixedly connected to a water bath tank (2) on the reciprocating power box (1), a dissolving cup (21) is fixedly connected to the water bath tank (2), the dissolving cup (21) corresponds to the stirring assembly, and a heating block (22) is fixedly connected to the bottom of the water bath tank (2).
2. A high efficiency automatic release rate sampling system according to claim 1, wherein said rotating rods (41) are provided with four sets, the top end of said rotating rods (41) extends into the rotating power box (3) and is fixedly connected with gears (43), and four said gears (43) are rotatably connected through timing belts (42).
3. An efficient automatic release rate sampling system according to claim 2, characterized in that the first motor (4) is fixedly connected to the rotary power box (3), and the output end of the first motor (4) is fixedly connected to the center of the gear (43).
4. An efficient automatic release rate sampling system according to claim 1, wherein a second motor (7) is fixedly connected in the reciprocating power box (1), the output end of the second motor (7) is fixedly connected with a reciprocating screw rod (71), a reciprocating plate (82) is in threaded connection with the reciprocating screw rod (71), and one end of the connecting plate (8) far away from the lantern ring (81) is fixedly connected with the reciprocating plate (82).
5. A high efficiency automatic release rate sampling system according to claim 1, wherein said stirring assembly comprises a stirring paddle (6), said stirring paddle (6) being screwed onto the telescopic rod (5).
6. A high efficiency, automatic release rate sampling system according to claim 1, wherein said agitator assembly comprises a rack (61), said rack (61) being threaded onto a telescoping rod (5).
CN202123300991.XU 2021-12-27 2021-12-27 Efficient automatic release rate sampling system Active CN216771678U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202123300991.XU CN216771678U (en) 2021-12-27 2021-12-27 Efficient automatic release rate sampling system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202123300991.XU CN216771678U (en) 2021-12-27 2021-12-27 Efficient automatic release rate sampling system

Publications (1)

Publication Number Publication Date
CN216771678U true CN216771678U (en) 2022-06-17

Family

ID=81969070

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202123300991.XU Active CN216771678U (en) 2021-12-27 2021-12-27 Efficient automatic release rate sampling system

Country Status (1)

Country Link
CN (1) CN216771678U (en)

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