CN216764926U - Amplification device for nucleic acid detection - Google Patents
Amplification device for nucleic acid detection Download PDFInfo
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- CN216764926U CN216764926U CN202122687502.4U CN202122687502U CN216764926U CN 216764926 U CN216764926 U CN 216764926U CN 202122687502 U CN202122687502 U CN 202122687502U CN 216764926 U CN216764926 U CN 216764926U
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Abstract
The utility model discloses an amplification device for nucleic acid detection, relates to the technical field of novel coronavirus nucleic acid detection, and solves the problems that the existing device for amplifying pathogen nucleic acid is complex and cannot be operated and used by one person, so that the pathogen nucleic acid is rapidly amplified for subsequent detection, the amplification device for nucleic acid detection comprises a box body, a top cover is arranged on the upper surface of the box body, a small motor is fixedly connected with the upper surface of the top cover, the output end of the small motor is fixedly connected with a rotating shaft, the outer surface of the rotating shaft is fixedly connected with a mounting ring, the outer surface of the mounting ring is fixedly connected with a mixing rod, the inner bottom wall of the box body is fixedly connected with a limiting frame, the inner wall fixedly connected with heating plate of spacing frame has realized can making pathogen nucleic acid's sample solution and amplification reagent mix mutually under the one-man operation's the condition fast and carry out the effect of amplification under suitable temperature.
Description
Technical Field
The utility model relates to the technical field of novel coronavirus nucleic acid detection, and more particularly relates to an amplification device for nucleic acid detection.
Background
Coronaviruses are nonsegmented, single-stranded, positive-strand RNA viruses belonging to the order Nidovirales (Nidovirales) Coronaviridae (Coronaviridae) the orthocoronaviridae (Orthocoronavirinae), which are divided into four genera, α, β, γ, and δ, depending on the serotype and genomic characteristics. There are 6 known coronaviruses that infect humans, including 229E and NL63 of the alpha genus, OC43 and HKU1 of the beta genus, the middle east respiratory syndrome-associated coronavirus (MERSR-CoV), and the Severe acute respiratory syndrome-associated coronavirus (SARSR-CoV). The novel coronavirus 2019-nCoV is a novel coronavirus belonging to the beta genus. At present, the physical and chemical properties of the SARS-CoV are relatively little recognized, and related property recognition mostly comes from the research on SARS-CoV and MERS-CoV.
In view of the unclear sources of viruses, toxin expelling time after infection, pathogenesis and the like, and no specific treatment method for diseases caused by the novel coronavirus exists at present, the method aims to better control the epidemic situation, reduce and reduce the disease transmission probability, further strengthen early discovery, isolation and treatment of cases, reduce the occurrence of nosocomial infection to the greatest extent and is the key for controlling the infection sources and reducing the morbidity at present.
When nucleic acid detection is carried out, pathogen nucleic acid needs to be amplified, but the existing device for amplifying pathogen nucleic acid is complex and cannot be operated and used by one person, so that the pathogen nucleic acid is rapidly amplified for subsequent detection.
SUMMERY OF THE UTILITY MODEL
Aiming at the defects of the technology, the utility model discloses an amplification device for nucleic acid detection, which can solve the problems that the existing device for amplifying pathogen nucleic acid in the prior art is complex and cannot be operated and used by one person, so that the pathogen nucleic acid is rapidly amplified for subsequent detection.
In order to achieve the purpose, the utility model provides the following technical scheme: the utility model provides an amplification device of nucleic acid detection, includes the box body, the upper surface of box body is provided with the top cap, the last fixed surface of top cap is connected with the micro motor, the output fixedly connected with pivot of micro motor, the outer fixed surface of pivot is connected with the collar, the outer fixed surface of collar is connected with the hybrid beam, the spacing frame of interior diapire fixedly connected with of box body, the inner wall fixedly connected with heating plate of spacing frame, interior diapire fixedly connected with fixation clamp splice of box body, box in the interior diapire fixedly connected with of box body amplifies, the upper surface of box is provided with the apron in the amplification, the last fixed surface of apron is connected with the connecting block.
As a further technical scheme of the utility model, the upper surface of the cover plate is fixedly connected with a liquid inlet connecting pipe.
As a further technical scheme of the utility model, the upper surface of the top cover is sequentially provided with a sample liquid inlet and an additive liquid inlet from left to right.
As a further technical scheme, one side surface of the amplification inner box is fixedly connected with a liquid outlet pipe, the outer surface of the liquid outlet pipe is fixedly connected with a liquid outlet connecting pipe, and the inner wall of the liquid outlet pipe is provided with a plugging head.
As a further technical scheme of the utility model, a battery seat is fixedly connected to the inner bottom wall of the box body.
As a further technical scheme of the utility model, the lower surface of the box body is fixedly connected with a supporting leg, and one end of the supporting leg is fixedly connected with an adsorption disc.
Positive and advantageous effects
1. According to the utility model, through the arrangement of the box body, the small motor, the rotating shaft, the mounting ring, the mixing rod and the heating sheet, the effect that the sample solution of pathogen nucleic acid and the amplification reagent can be quickly mixed and amplified at a proper temperature under the condition of single-person operation is realized.
According to the utility model, through the arrangement of the limiting frame, the fixing clamping block, the amplification inner box, the cover plate and the connecting block, the effects of limiting and fixing the position of the amplification inner box and preventing sample solution of pathogen nucleic acid from being leaked and spilled accidentally are realized.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without inventive exercise, wherein:
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a front cross-sectional structural view of the present invention;
FIG. 3 is a schematic right-side sectional view of the present invention;
FIG. 4 is a schematic view of an axial structure inside the case of the present invention;
FIG. 5 is a schematic bottom view of the axial structure of the present invention;
the mark in the figure is: 1. a box body; 2. a top cover; 3. a small-sized motor; 4. a rotating shaft; 5. a mounting ring; 6. a mixing rod; 7. a limiting frame; 8. a heating plate; 9. fixing the clamping block; 10. amplifying the inner box; 11. a cover plate; 12. connecting blocks; 13. a liquid inlet connecting pipe; 14. a sample fluid inlet; 15. an additive liquid inlet; 16. a liquid outlet pipe; 17. a liquid outlet connecting pipe; 18. a plugging head; 19. a battery holder; 20. supporting legs; 21. and (4) adsorbing the disc.
Detailed Description
The preferred embodiments of the present invention will be described below with reference to the accompanying drawings, and it should be understood that the embodiments described herein are merely for the purpose of illustrating and explaining the present invention and are not intended to limit the present invention.
Examples
As shown in fig. 1 to 5, the present invention provides the following technical solutions: the utility model provides a nucleic acid detection's amplification device, comprises a box bod 1, the upper surface of box body 1 is provided with top cap 2, the last fixed surface of top cap 2 is connected with small motor 3, small motor 3's output end fixedly connected with pivot 4, the outer fixed surface of pivot 4 is connected with collar 5, the outer fixed surface of collar 5 is connected with hybrid beam 6, the spacing frame 7 of inner bottom wall fixedly connected with of box body 1, the inner wall fixedly connected with heating plate 8 of spacing frame 7, inner bottom wall fixedly connected with fixation clamp splice 9 of box body 1, box 10 in the inner bottom wall fixedly connected with of box body 1 augments, the upper surface of box 10 is provided with apron 11 in the amplifications, the last fixed surface of apron 11 is connected with connecting block 12.
In the embodiment of the utility model, through the arrangement of the box body 1, the small motor 3, the rotating shaft 4, the mounting ring 5, the mixing rod 6 and the heating plate 8, the small motor 3 is arranged on the top cover 2 at the upper part of the box body 1, the small motor 3 is connected with the rotating shaft 4, the mounting ring 5 is fixed on the lower end surface of the rotating shaft 4, the mixing rod 6 is fixed on the surface of the mounting ring 5, and the heating plate 8 is arranged on the inner wall of the limit frame 7 close to the amplification inner box 10, so that when the pathogen nucleic acid solution and the amplification reagent solution are mixed, the small motor 3 drives the rotating shaft 4 to rotate, the mixing rod 6 stirs and mixes the liquid in the amplification inner box 10, the heating plate 8 provides a temperature environment suitable for the reaction of the two, the nucleic acid is amplified in large quantity, the subsequent detection is convenient, meanwhile, the device is designed into the box body 1, the single-person operation experiment is convenient, and the purpose that the sample solution of the pathogen nucleic acid and the amplification reagent can be mixed and carried out at the proper temperature under the condition of single-person operation is realized The effect of amplification, through the setting of fixed clamp splice 9, the position of box 10 in can the fixed amplification, through the setting of box 10 in the amplification, can make things convenient for pathogen nucleic acid to amplify, through the setting of apron 11 and connecting block 12, can link together apron 11 and top cap 2.
Specifically, the upper surface of the cover plate 11 is fixedly connected with a liquid inlet connecting pipe 13.
In this embodiment: by arranging the liquid inlet connecting pipe 13, liquid can conveniently enter the amplification inner box 10.
Specifically, the upper surface of the top cover 2 is provided with a sample liquid inlet 14 and an additive liquid inlet 15 in sequence from left to right.
In this embodiment: by the arrangement of the sample liquid inlet 14 and the additive liquid inlet 15, the pathogen nucleic acid solution and the amplification reagent can be poured into the apparatus separately.
Specifically, a liquid outlet pipe 16 is fixedly connected to one side surface of the amplification inner box 10, a liquid outlet connecting pipe 17 is fixedly connected to the outer surface of the liquid outlet pipe 16, and a blocking head 18 is arranged on the inner wall of the liquid outlet pipe 16.
In this embodiment: through the arrangement of the liquid outlet pipe 16, the liquid outlet connecting pipe 17 and the blocking head 18, the solution in the amplification inner box 10 can be poured out of the device conveniently.
Specifically, a battery holder 19 is fixedly connected to the inner bottom wall of the case 1.
In this embodiment: the device can be powered by the battery holder 19.
Specifically, the lower fixed surface of box body 1 is connected with supporting leg 20, and the one end fixedly connected with of supporting leg 20 adsorbs dish 21.
In this embodiment: the supporting legs 20 and the adsorption disc 21 are arranged, so that the device can be conveniently supported when being placed on a table top.
The present invention will be further described below in conjunction with specific examples to more clearly understand the present invention.
When the amplification device for nucleic acid detection is used, the small motor 3 is arranged on the top cover 2 at the upper part of the box body 1, the small motor 3 is connected with the rotating shaft 4, the surface of the lower end of the rotating shaft 4 is fixedly provided with the mounting ring 5, the surface of the mounting ring 5 is fixedly provided with the mixing rod 6, the heating plate 8 is arranged on the inner wall of the limiting frame 7 close to the amplification inner box 10, thus, when the pathogen nucleic acid solution and the amplification reagent solution are mixed, the small-sized motor 3 drives the rotating shaft 4 to rotate, so that the mixing rod 6 stirs and mixes the liquid in the amplification inner box 10, the heating sheet 8 provides a temperature environment suitable for the reaction of the two, the nucleic acid is amplified in a large amount, the subsequent detection is convenient, meanwhile, the device is designed into a box body 1, so that the operation experiment can be conveniently carried out by a single person, and the effects of quickly mixing the sample solution of the pathogen nucleic acid with the amplification reagent and amplifying at a proper temperature under the condition of single-person operation are realized.
Although specific embodiments of the present invention have been described above, it will be understood by those skilled in the art that these specific embodiments are merely illustrative and that various omissions, substitutions and changes in the form of the detail of the methods and systems described above may be made by those skilled in the art without departing from the spirit and scope of the utility model. For example, it is within the scope of the present invention to combine the steps of the above-described methods to perform substantially the same function in substantially the same way to achieve substantially the same result. Accordingly, the scope of the utility model is to be limited only by the following claims.
Claims (6)
1. An amplification device for nucleic acid detection, comprising a cartridge (1), characterized in that: the upper surface of box body (1) is provided with top cap (2), the last fixed surface of top cap (2) is connected with micro motor (3), the output end fixedly connected with pivot (4) of micro motor (3), the outer fixed surface of pivot (4) is connected with collar (5), the outer fixed surface of collar (5) is connected with hybrid pole (6), the spacing frame of inner diapire fixedly connected with (7) of box body (1), the inner wall fixedly connected with heating plate (8) of spacing frame (7), the inner diapire fixedly connected with fixation clamp splice (9) of box body (1), box (10) in the inner diapire fixedly connected with of box body (1) augments, the upper surface of box (10) in the augmentations is provided with apron (11), the last fixed surface of apron (11) is connected with connecting block (12).
2. The nucleic acid detecting amplification apparatus of claim 1, wherein: the upper surface of the cover plate (11) is fixedly connected with a liquid inlet connecting pipe (13).
3. The nucleic acid detecting amplification apparatus of claim 1, wherein: the upper surface of the top cover (2) is sequentially provided with a sample liquid inlet (14) and an additive liquid inlet (15) from left to right.
4. The nucleic acid detecting amplification apparatus of claim 1, wherein: one side face of the amplification inner box (10) is fixedly connected with a liquid outlet pipe (16), the outer surface of the liquid outlet pipe (16) is fixedly connected with a liquid outlet connecting pipe (17), and the inner wall of the liquid outlet pipe (16) is provided with a plugging head (18).
5. The nucleic acid detecting amplification apparatus according to claim 1, wherein: the inner bottom wall of the box body (1) is fixedly connected with a battery seat (19).
6. The nucleic acid detecting amplification apparatus according to claim 1, wherein: the lower fixed surface of box body (1) is connected with supporting leg (20), the one end fixedly connected with of supporting leg (20) adsorbs dish (21).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122687502.4U CN216764926U (en) | 2021-11-05 | 2021-11-05 | Amplification device for nucleic acid detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122687502.4U CN216764926U (en) | 2021-11-05 | 2021-11-05 | Amplification device for nucleic acid detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216764926U true CN216764926U (en) | 2022-06-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122687502.4U Active CN216764926U (en) | 2021-11-05 | 2021-11-05 | Amplification device for nucleic acid detection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216764926U (en) |
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2021
- 2021-11-05 CN CN202122687502.4U patent/CN216764926U/en active Active
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