CN216676018U

CN216676018U - U-shaped slide rail device and large animal brain stereotaxic instrument

Info

Publication number: CN216676018U
Application number: CN202121373947.9U
Authority: CN
Inventors: 黄素梅; 王乐城
Original assignee: Shenzhen Huayang Biotechnology Co ltd
Current assignee: Shenzhen Huayang Biotechnology Co ltd
Priority date: 2021-06-21
Filing date: 2021-06-21
Publication date: 2022-06-07
Anticipated expiration: 2031-06-21

Abstract

The utility model discloses a U-shaped sliding rail device which comprises a U-shaped sliding rail mechanism and a head fixing mechanism, wherein the U-shaped sliding rail mechanism comprises a supporting block, the supporting block is detachably provided with a connecting arm through a bolt, the connecting arm is sleeved with a sliding seat, a rolling mechanism is arranged in the sliding seat, and the rolling mechanism is attached to and rolls on the connecting arm; the head fixing mechanism comprises an ear fixing mechanism and an eye and mouth fixing mechanism. According to the utility model, the X/Z axis operating arm adopts a rolling mode on the U-shaped track, the movement is smooth, the precision is easy and stable to control, meanwhile, a high-precision displacement sensor is favorably installed, the displacement data is stably controlled and displayed in real time, and the use precision is improved. The animal brain stereotaxic apparatus comprising the U-shaped slide rail mechanism and the head fixing mechanism can be widely applied to brain science basic research.

Description

U-shaped slide rail device and large animal brain stereotaxic instrument

Technical Field

The utility model relates to the field of animal experiments, in particular to a U-shaped sliding rail device.

Background

The brain stereotaxic apparatus is important research equipment for preclinical brain disease research, and it utilizes the special marks (such as bregma) on the surface of animal skull as basic reference point, and combines with brain atlas, and utilizes the movement of its three axes to define the position of some nerve structure (nucleus) in animal skull, and further makes injection, stimulation and electroencephalography on the nerve structure, so that it can be used for animal model and related research of diseases of Parkinson's disease, epilepsy, senile dementia, intracerebral tumor and brain injury, etc.

Basic research on brain science about the above brain diseases requires establishment of animal models, and experimental studies on medium and large animals such as non-human primates, dogs, and pigs, in addition to small animals such as mice, rats, and rabbits, are essential and have been growing. There is an increasing demand for stereotaxic apparatus for the brain of large animals.

However, with respect to existing large animal brain stereotaxic apparatus, the existing technology is well-balanced and often has problems: (1) the moving in the Y-axis direction (namely the U-shaped track direction) adopts a hand-push mode, so that the moving cannot be stably moved and the hand feeling is poor, and more importantly, a displacement sensor cannot be additionally arranged, so that the moving precision is difficult to control, the precision is low and the efficiency is low; (2) in the aspect of fixing ears and eyes of large animals, the heads of the large animals are complicated to fix due to complicated structures and large sizes of the heads, and the heads of the large animals need to be adjusted in a multi-dimensional direction and position.

SUMMERY OF THE UTILITY MODEL

The utility model aims to solve the defects in the prior art and provides a U-shaped sliding rail device.

In order to achieve the purpose, the utility model adopts the following technical scheme:

a U-shaped sliding rail device comprises a U-shaped sliding rail mechanism and a head fixing mechanism, wherein the U-shaped sliding rail mechanism comprises a supporting block, a connecting arm is detachably mounted on the supporting block through a bolt, a sliding seat is sleeved on the connecting arm, a rolling mechanism is mounted inside the sliding seat, and the rolling mechanism rolls on the connecting arm in a fitting mode; a screw is arranged on the outer side of the sliding seat to abut against and adjust the tightness of the rolling mechanism and the connecting arm; the inside first gear stick that still is equipped with of sliding seat, first gear stick with the first rack that is equipped with on the linking arm meshes mutually, first gear stick trailing end connection first twist grip.

A first brake handle is installed on the outer side of the sliding seat in a threaded mode, and a connecting support is arranged at the top of the sliding seat.

The head fixing mechanism comprises an ear fixing mechanism and an eye and mouth fixing mechanism; the ear fixing mechanism comprises a guide block detachably mounted at the bottom of the connecting arm through a bolt, a pressure bearing is mounted inside the guide block, the pressure bearing is tightly fitted with an adjusting handle, the adjusting handle is provided with a threaded lug, and the threaded lug penetrates through the guide block; and the bottom of the guide block is in threaded connection with a second brake handle which is propped against and fixed with the threaded lug.

The eye mouth fixing mechanism comprises a first fixing block and a first sliding rod, wherein the first fixing block and the first sliding rod are detachably connected with a supporting block, a second rack is arranged on the outer side of the first sliding rod and is meshed with a second gear rod connected with the first fixing block, the two ends of the second gear rod are also sleeved and connected with a third brake handle and a third rotating handle, and an eye socket clamp can be detached from the end portion of the first sliding rod.

Eye mouth fixed establishment still includes second slide bar, second fixed block and third rack, first slide bar cover is equipped with the second slide bar, second slide bar lateral part is equipped with the third rack, the third rack meshes with the third gear stick mutually, the third gear stick runs through to be installed in the second fixed block, the third gear stick both ends are also the suit simultaneously, are connected with fourth brake lever and second twist grip, the second fixed block is dismantled and is installed the tongue piece.

The first fixing block is connected with the supporting block; and threaded holes are formed in two ends of the first fixing block and two ends of the second fixing block and are respectively connected with external threads of the third brake handle and the fourth brake handle.

The utility model provides a big animal brain stereotaxic instrument, still includes X/Z axle operating arm and base, the base includes bottom plate, bracing piece and fixed cover, X/Z axle operating arm passes through connect the support with U type slide rail mechanism connects, U type slide rail mechanism is connected with the base through fixed cover.

The U-shaped sliding rail mechanism is sleeved with the plurality of sliding seats through connection, and the plurality of X/Z axis operating arms are installed at the same time.

The utility model has the beneficial effects that:

according to the utility model, the rolling mechanism is arranged on the U-shaped track in the Y-axis direction, wherein the rolling mechanism is matched with the screw rod through threads, rolling motion is performed on a plane in the back-and-forth sliding process, the rolling mechanism is similar to the motion between train wheels and the track, part loss caused by friction is hardly generated, and the rolling mechanisms and the connecting arms are matched and tightened through adjusting screws of the calibration equipment, so that the gap between the rolling mechanisms and the connecting arms is eliminated, the stability and the accuracy of movement in the Y-axis direction are improved, meanwhile, the operation replaces the traditional direct pushing mode, the movement is smoother, the accuracy adjustment is more stable, a high-accuracy displacement sensor is favorably installed, the displacement data are stably controlled and displayed in real time, and the use accuracy is improved; secondly, head fixed establishment is including being equipped with ear, eye mouth fixed establishment, and ear and eye mouth are fixed also adopts rolling structure and screw drive mechanism, and a plurality of dimension removal of complicacy adjust the operating procedure reduce in a large number, operate steadily, and easily control the removal precision, have improved work efficiency.

Drawings

Fig. 1 is a schematic partial structural view of a U-shaped slide rail mechanism of a proposed U-shaped slide rail device;

fig. 2 is an exploded view of an ear fixing mechanism of a U-shaped sliding rail device;

fig. 3 is an exploded view of a sliding seat of the proposed U-shaped sliding rail device;

fig. 4 is a schematic overall perspective view of the proposed U-shaped slide rail device;

fig. 5 is a schematic diagram of an overall explosion structure of the proposed U-shaped slide rail device.

In the figure: 1. a U-shaped slide rail mechanism; 10. a support block; 11. a connecting arm; 111. a first rack; 12. a sliding seat; 121. a rolling mechanism; 122. a screw; 123. connecting a support; 124. A first brake handle; 13. a first gear bar; 131. a first rotating handle; 2. a head fixing mechanism; 21. an ear fixing mechanism; 211. a guide block; 212. a pressure bearing; 213. adjusting the handle; 214. a threaded ear post; 215. a second brake handle; 22. an eye and mouth fixing mechanism; 221. A first fixed block; 222. a first slide bar; 2221. a second rack; 223. a second gear bar; 2231. a third brake handle; 2232. a third rotating handle; 224. eye socket clamps; 225. A second slide bar; 226. a second fixed block; 227. a third rack; 228. a third gear bar; 2281. a fourth brake handle; 2282. a second rotating handle; 229. a tongue block; 3. an X/Z axis operation arm; 31. a base; 32. a base plate; 33. a support bar; 34. and (4) fixing sleeves.

Detailed Description

The technical solution of the present patent will be described in further detail with reference to the following embodiments.

Reference will now be made in detail to embodiments of the present patent, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present patent and are not to be construed as limiting the present patent.

In the description of this patent, it is to be understood that the terms "center," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientations and positional relationships indicated in the drawings for the convenience of describing the patent and for the simplicity of description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are not to be considered limiting of the patent.

In the description of this patent, it is noted that unless otherwise specifically stated or limited, the terms "mounted," "connected," and "disposed" are to be construed broadly and can include, for example, fixedly connected, disposed, detachably connected, disposed, or integrally connected and disposed. The specific meaning of the above terms in this patent may be understood by those of ordinary skill in the art as appropriate.

Referring to fig. 1, 3 and 5, a U-shaped sliding rail device includes a U-shaped sliding rail mechanism 1 and a head fixing mechanism 2, wherein the U-shaped sliding rail mechanism 1 includes a supporting block 10, the supporting block 10 is detachably mounted with a connecting arm 11 through a bolt, the connecting arm 11 is sleeved with a sliding seat 12, a rolling mechanism 121 is mounted inside the sliding seat 12, and the rolling mechanism 121 rolls on the connecting arm 11 in an attaching manner; a screw 122 is arranged on the outer side of the sliding seat 12 to abut against and adjust the tightness of the rolling mechanism 121 and the connecting arm 11; a first gear rod 13 is further arranged inside the sliding seat 12, the first gear rod 13 is meshed with a first rack 111 arranged on the connecting arm 11, and the tail end of the first gear rod 13 is connected with a first rotating handle 131; the rolling mechanism 121 is arranged on the U-shaped rail in the Y-axis direction, wherein the rolling mechanism 121 is matched with a screw rod through threads, rolling motion is performed on a plane in the back-and-forth sliding process, similar to the motion between train wheels and the rail, part loss caused by friction is hardly generated, and the rolling mechanisms 121 and the connecting arm 11 are matched and fastened through adjusting screws of the calibration equipment, so that the gap between the rolling mechanisms and the connecting arm is eliminated, and the stability and the accuracy of movement in the Y-axis direction are improved.

Referring to fig. 1 and 3, a first brake handle 124 is installed on the outer side of the sliding seat 12 in a threaded manner, and a connecting support 123 is arranged at the top of the sliding seat 12; the first brake handle 124 is screwed against the connecting arm 11 to prevent displacement of the adjusted slide shoe 12.

Referring to fig. 1, 2 and 5, the head fixing mechanism 2 includes an ear fixing mechanism 21 and an eye-mouth fixing mechanism 22; the ear fixing mechanism 21 comprises a guide block 211 detachably mounted at the bottom of the connecting arm 11 through a bolt, a pressure bearing 212 is mounted inside the guide block 211, the pressure bearing 212 is tightly fitted with an adjusting handle 213, the adjusting handle 213 is provided with a threaded ear rod 214, and the threaded ear rod 214 penetrates through the guide block 211; the bottom of the guide block 211 is in threaded connection with a second brake handle 215 which is propped against and fixed with the threaded lug 214; head fixed establishment 2, the ear adopts lead screw transmission structure, operates steadily, and easily controls the removal precision.

Referring to fig. 1 and 5, the eye and mouth fixing mechanism 22 includes a first fixing block 221 and a first slide bar 222 detachably connected to a support block 10, a second rack 2221 is provided on the outer side of the first slide bar 222 and engaged with a second gear bar 223 connected to the first fixing block 221, both ends of the second gear bar 223 are also sleeved with and connected to a third brake handle 2231 and a third rotating handle 2232, and an eye socket clamp 224 is detachably mounted on the end of the first slide bar 222, so as to further fix the eye socket and mouth of an animal, position and fix in multiple directions, and further effectively improve the stability of the animal and improve the working accuracy.

Referring to fig. 1 and 5, the eye-mouth fixing mechanism 22 further includes a second slide bar 225, a second fixing block 226 and a third rack 227, the second slide bar 225 is sleeved on the first slide bar 222, the third rack 227 is disposed on the side of the second slide bar 225, the third rack 227 is engaged with a third gear bar 228, the third gear bar 228 is mounted on the second fixing block 226 in a penetrating manner, both ends of the third gear bar 228 are also sleeved and connected with a fourth brake handle 2281 and a second rotating handle 2282, a tongue block 229 is detachably mounted on the second fixing block 226, the mouth of the animal is further fixed, and the second rack 227 is engaged with the third gear bar 228 in the second fixing block 226, so as to adjust the height of the tongue block 229 and facilitate adjustment of the head angle of the animal.

Referring to fig. 1 and 5, the first fixing block 221 is connected to the supporting block 10; threaded holes are further formed in two ends of the first fixing block 221 and the second fixing block 226 and are respectively connected with external threads of the third brake handle 2231 and the fourth brake handle 2281, and the third brake handle 2231 and the fourth brake handle 2281 are mounted with the threaded holes in two ends of the first fixing block 221 and the second fixing block 226 through the external threads, so that the positions of the first fixing block 221 and the second fixing block 226 can be easily screwed and fixed.

Referring to fig. 4-5, the stereotaxic apparatus for brain of a large animal comprises an X/Z axis operating arm 3 and a base 31, wherein the base 31 comprises a bottom plate 32, a supporting rod 33 and a fixing sleeve 34, the X/Z axis operating arm 3 is connected with a U-shaped slide rail mechanism 1 through a connecting support 123, and the U-shaped slide rail mechanism 1 is connected with the base 31 through the fixing sleeve 34.

Referring to fig. 4-5, the U-shaped slide rail mechanism 1 is connected to and sleeved with a plurality of the slide bases 12, and is also provided with a plurality of the X/Z-axis operating arms 3.

The working principle is as follows: firstly adjusting the U-shaped slide rail mechanism 1 according to the body sizes and head positions of different experimental animals, such as a monkey, firstly performing anesthesia, rotating the fourth brake handle 2281 and the second rotary handle 2282 to drive the third gear rod 228 to move in an engaged manner with the third rack 227, thereby adjusting the height of the second fixed block 226, then opening the mouth of the animal to be supported by the tongue block 229, adjusting the ear hole of the threaded ear rod 214 in the ear fixing mechanism 21, moving the threaded ear rod 214 through the adjusting handle 213, secondly fixing the head of the animal by abutting against the fixed threaded ear rod 214 through the second brake handle 215, controlling the engagement of the first slide rod 222 and the second gear rod 223 through the third rotary handle 2232 and the third brake handle 2231, further adjusting the front-back distance of the first slide rod 222 until the eye socket clamp 224 clamps the eye socket of the monkey to perform positioning clamping, and driving the first gear rod 13 to be engaged with the first rack 111 on the connecting arm 11 by rotating the first rotary handle 131, and the rolling mechanism 121 is used for assisting the movement of the sliding seat, so that the position of the sliding seat 12 is adjusted, and the X/Z axis operating arm 3 can conveniently perform experiments according to the positioning.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.

Claims

1. A U-shaped sliding rail device comprises a U-shaped sliding rail mechanism (1) and a head fixing mechanism (2), and is characterized in that the U-shaped sliding rail mechanism (1) comprises a supporting block (10), the supporting block (10) is detachably provided with a connecting arm (11) through a bolt, the connecting arm (11) is sleeved with a sliding seat (12), a rolling mechanism (121) is arranged inside the sliding seat (12), and the rolling mechanism (121) is attached to and rolls on the connecting arm (11); a screw (122) is arranged on the outer side of the sliding seat (12) to abut against and adjust the tightness of the rolling mechanism (121) and the connecting arm (11); the inside first gear stick (13) that still is equipped with of sliding seat (12), first gear stick (13) with first rack (111) that are equipped with on linking arm (11) mesh mutually, first gear stick (13) tail end connection first twist grip (131).

2. The U-shaped sliding rail device according to claim 1, wherein the sliding seat (12) is externally and threadedly provided with a first brake handle (124), and the top of the sliding seat (12) is provided with a connecting support (123).

3. A U-shaped slide rail device according to claim 1, wherein the head fixing mechanism (2) comprises an ear fixing mechanism (21) and an eye and mouth fixing mechanism (22); the ear fixing mechanism (21) comprises a guide block (211) detachably mounted at the bottom of the connecting arm (11) through a bolt, a pressure bearing (212) is mounted inside the guide block (211), the pressure bearing (212) is tightly sleeved with an adjusting handle (213), the adjusting handle (213) is provided with a threaded lug rod (214), and the threaded lug rod (214) penetrates through the guide block (211); the bottom of the guide block (211) is in threaded connection with a second brake handle (215) which is propped against and fixed with the threaded lug (214).

4. The U-shaped sliding rail device according to claim 3, wherein the eye-mouth fixing mechanism (22) comprises a first fixing block (221) and a first sliding rod (222) which are detachably connected with the supporting block (10), a second rack (2221) is arranged on the outer side of the first sliding rod (222) and is meshed with a second gear rod (223) connected with the first fixing block (221), both ends of the second gear rod (223) are also sleeved and connected with a third brake handle (2231) and a third rotating handle (2232), and an eye socket clamp (224) is detachably connected with the end of the first sliding rod (222).

5. The U-shaped sliding rail device according to claim 4, wherein the eye-mouth fixing mechanism (22) further comprises a second sliding rod (225), a second fixing block (226) and a third rack (227), the second sliding rod (225) is sleeved on the first sliding rod (222), the third rack (227) is arranged on the side of the second sliding rod (225), the third rack (227) is meshed with a third gear rod (228), the third gear rod (228) is installed on the second fixing block (226) in a penetrating manner, both ends of the third gear rod (228) are simultaneously sleeved and connected with a fourth brake handle (2281) and a second rotating handle (2282), and a tongue block (229) is installed on the second fixing block (226) in a detachable manner.

6. A U-shaped slide rail device according to claim 5, characterized in that the first fixing block (221) is connected with the supporting block (10); and threaded holes are further formed in two ends of the first fixing block (221) and the second fixing block (226) and are respectively connected with external threads of the third brake handle (2231) and the fourth brake handle (2281).

7. A stereotaxic apparatus for brain of large animals, comprising the U-shaped slide rail mechanism (1) and the head fixing mechanism (2) according to any one of claims 1 to 6, and further comprising an X/Z axis operating arm (3) and a base (31), wherein the base (31) comprises a bottom plate (32), a support rod (33) and a fixing sleeve (34), the X/Z axis operating arm (3) is connected with the U-shaped slide rail mechanism (1) through a connecting support (123), and the U-shaped slide rail mechanism (1) is connected with the base (31) through the fixing sleeve (34).

8. The stereotaxic apparatus according to claim 7, wherein the U-shaped slide rail mechanism (1) is connected with a plurality of slide seats (12) and a plurality of X/Z-axis operation arms (3) are installed at the same time.