CN216603690U

CN216603690U - Syringe for mouse brain compensation and toxicity attack

Info

Publication number: CN216603690U
Application number: CN202123079231.0U
Authority: CN
Inventors: 黄镇; 方国良; 施競; 严永庆; 李朋洋; 李林华; 陆艳芝; 梁瀚之
Original assignee: Walvax Biotechnology Co ltd; Yuxi Walvax Biotechnology Co ltd
Current assignee: Walvax Biotechnology Co ltd; Yuxi Walvax Biotechnology Co ltd
Priority date: 2021-12-09
Filing date: 2021-12-09
Publication date: 2022-05-27
Anticipated expiration: 2031-12-09

Abstract

The utility model discloses an injector for mouse brain poison compensation, which comprises an outer cylinder, wherein the inner wall of the outer cylinder is connected with an inner cylinder in a sliding way, the bottom of the inner cylinder extends to the lower part of the outer cylinder, the inner part of the inner cylinder penetrates through and is fixedly connected with a needle cylinder, a piston rod is arranged in the needle cylinder, the top of the piston rod penetrates through the top of the outer cylinder in a sliding way and is fixedly connected with a first pressing plate, the tops of two sides of the outer cylinder are fixedly connected with side plates, the outer wall of the outer cylinder is provided with a limiting component for limiting the inner cylinder, and a control component for releasing the braking of the inner cylinder is arranged in one of the side plates. The device is convenient to use continuously.

Description

Syringe for mouse brain compensation and toxicity attack

Technical Field

The utility model relates to the technical field of injectors, in particular to an injector for mouse brain compensation and toxicity attack.

Background

The vaccine strain is usually selected from strains with high protection efficiency, small immunization dose, easy culture and low production cost. In the case where the background knowledge of some bacterial studies is obscure and virulence factors are not yet clear, the screening method for vaccine strains is usually to sequentially measure the virulence of each isolate.

When a virus attacking experiment is carried out on a mouse brain, a microinjector is required to be used for injecting attack bacteria liquid to a designated position of the mouse brain, the volume of a reagent injected by one mouse is 0.03ml, when workers inject the reagent, the microinjector sucks the attack bacteria liquid to the maximum range, then one hand holds the mouse and the other hand injects the reagent, the range change of the injector is checked through eyes, the error is large, the injected dose cannot be kept consistent, and the experiment result is further influenced.

SUMMERY OF THE UTILITY MODEL

Aiming at the defects of the prior art, the utility model provides the injector for supplementing and counteracting the poison of the mouse brain, which can reduce the injection error.

In order to solve the problems that the range of the existing injector is too large, a mouse uses few reagents, a worker needs to hold the mouse with one hand and inject with the other hand when injecting, the injection amount can only be checked through eyes, the error is large, the injected dose cannot be kept consistent, and the experimental result is influenced, the technical scheme of the utility model is as follows: the utility model provides an injector for mouse brain benefit is attacked poison, includes the urceolus, the inner wall sliding connection of urceolus has the inner tube, the bottom of inner tube extends to the below of urceolus, fixedly connected with cylinder is run through to the inside of inner tube, the inside of cylinder is provided with the piston rod, the top of piston rod runs through the top of urceolus and the first clamp plate of fixedly connected with, the equal fixedly connected with curb plate in both sides top of urceolus, the outer wall of urceolus is provided with and is used for carrying out spacing subassembly to the inner tube, one of them the inside of curb plate is provided with the control assembly who is used for relieving the inner tube braking.

Preferably, the limiting component comprises a clamping plate which penetrates through the outer wall of the outer barrel in a sliding mode, one side of the inner barrel is provided with a plurality of clamping grooves which are clamped with the clamping plate at equal intervals, the clamping plate is far away from one end fixedly connected with limiting plates of the outer barrel, two first tension springs are symmetrically arranged between the limiting plates and the outer barrel, and inclined holes are formed in the clamping plate and used for achieving the limiting function of the inner barrel.

Preferably, the control assembly comprises a vertical plate which penetrates through the top of the side plate in a sliding mode, a second pressing plate is fixedly connected to the top of the vertical plate, a spring is fixedly connected between the bottom of the second pressing plate and the top of the side plate, and the spring is sleeved on the vertical plate and used for releasing the clamping state of the clamping plate and the clamping groove and facilitating continuous use.

Preferably, the bottom of riser sets up and extends to the inside of inclined hole for the slope, the inclined hole is close to one side inner wall of limiting plate and sets up for the slope, the riser bottom is inconsistent with one side inner wall that the inclined hole is close to the limiting plate, is convenient for promote the cardboard.

Preferably, two second extension springs which are symmetrically arranged are fixedly connected between the inner wall of the top of the outer cylinder and the top of the inner cylinder, so that the clamping plate can rebound conveniently.

Preferably, the bottom of the side plate and the top of the first pressing plate are both provided with anti-slip pads, so that the injection failure caused by hand slip is avoided.

Compared with the prior art, the utility model has the following beneficial effects:

1. in the utility model, the forefinger and the middle finger of one hand hook the bottoms of the two side plates, the other hand holds the inner cylinder and presses the second pressing plate, the second pressing plate drives the vertical plate to vertically move downwards and extrude the spring, the vertical plate slides on the inner wall of the inclined hole and can push the clamping plate to transversely move, the clamping plate drives the limiting plate to transversely move and stretches the first tension spring, the clamping plate and the clamping groove are released from a clamping state at the moment, the inner cylinder vertically moves upwards under the action of the tension force of the second tension spring, the hand holding the inner cylinder slowly moves towards the direction of the outer cylinder at the moment, the inner cylinder drives the needle cylinder and the piston rod to slowly vertically move upwards, when the next clamping groove moves to the position of the clamping plate, the second pressing plate is directly loosened, the second pressing plate rebounds under the action of the spring, the clamping plate returns to the initial position under the action of the first tension spring, and then the clamping plate is clamped with the next clamping groove again, the first pressing plate is pressed by a thumb at the moment, the first pressing plate drives the piston rod to vertically move downwards, the piston rod injects the reagent in the inner cylinder into the mouse body until the bottom of the first pressing plate is abutted against the top of the outer cylinder, the first pressing plate cannot continuously move downwards at the moment, the injection amount of the reagent is close to 0.03ml, after the injection is completed, the first pressing plate is loosened by the thumb, the second pressing plate is pressed again in the same way when the injection is needed, the operation is repeated, the function of quantitatively injecting the reagent can be realized, the dosage of each injection is ensured to be kept consistent, and the accuracy of the experimental result is further improved;

2. in the utility model, when reagent is extracted, the index finger and the middle finger of one hand hook the bottoms of the two side plates, the other hand holds the inner cylinder, presses the second pressing plate to push the first pressing plate to move the piston rod to the bottommost part of the needle cylinder, then inserts a needle head (not shown in the figure) on the needle cylinder into the reagent bottle, then pulls the side plates upwards to drive the piston rod to move upwards, so that the reagent can be extracted into the needle cylinder, when the clamping plate is positioned in the clamping groove at the top, the second pressing plate is released, the plate is clamped with the clamping groove to brake the inner cylinder, and before injection, the first pressing plate is pressed downwards to enable the bottom of the first pressing plate to be abutted against the top of the outer cylinder.

The injection device is simple in structure, the function of quantitatively injecting the reagent can be easily realized by directly pressing the first pressing plate without observing scales, so that errors are avoided, the accuracy of an experimental result is improved, the clamping state of the clamping plate and the clamping groove can be relieved by pressing the second pressing plate again, the continuous use of the device is facilitated, the working efficiency is improved, and the material for selecting the injector needs to resist high pressure and high temperature.

Drawings

FIG. 1 is a three-dimensional view of a syringe for replenishing and counteracting toxic substances in mouse brain according to the present invention;

FIG. 2 is a schematic sectional view of the injector for replenishing and counteracting toxic substance in the mouse brain according to the present invention;

FIG. 3 is an enlarged view of portion A of the present invention;

FIG. 4 is a three-dimensional schematic view of a card of the present invention.

In the figure: 1. a first platen; 2. a piston rod; 3. an inclined hole; 4. an outer cylinder; 5. an inner barrel; 6. a needle cylinder; 7. a card slot; 8. clamping a plate; 9. a limiting plate; 10. a first tension spring; 11. a vertical plate; 12. a side plate; 13. a spring; 14. a second platen; 15. the second extension spring.

Detailed Description

The technical solutions of the present invention will be described in further detail with reference to the drawings and specific examples, but the present invention is not limited to the following technical solutions.

Example 1

Referring to fig. 1-4, an injector for mouse brain toxicity compensation and attack includes an outer barrel 4, an inner barrel 5 is connected to the inner wall of the outer barrel 4 in a sliding manner, a guide rail is fixedly mounted on the inner wall of the outer barrel 4, a slider is fixedly mounted on the outer wall of the inner barrel 5 and is connected with the guide rail in a sliding manner, the bottom of the inner barrel 5 extends to the lower side of the outer barrel 4, a needle barrel 6 is fixedly connected to the inner barrel 5 in a penetrating manner, the inner barrel 5 and the needle barrel 6 are bonded through glue, a piston rod 2 is arranged inside the needle barrel 6, the top of the piston rod 2 penetrates through the top of the outer barrel 4 and is fixedly connected with a first pressing plate 1, side plates 12 are fixedly connected to the tops of two sides of the outer barrel 4, a limiting component for limiting the inner barrel 5 is arranged on the outer wall of the outer barrel 4, and a control component for releasing braking of the inner barrel 5 is arranged inside one side plate 12.

Example 2

Referring to fig. 1-4, an injector for mouse brain toxicity compensation and attack includes an outer barrel 4, an inner barrel 5 is connected to the inner wall of the outer barrel 4 in a sliding manner, the bottom of the inner barrel 5 extends to the lower part of the outer barrel 4, a needle barrel 6 is fixedly connected to the inside of the inner barrel 5 in a penetrating manner, the inner barrel 5 and the needle barrel 6 are bonded by glue, a piston rod 2 is arranged inside the needle barrel 6, the top of the piston rod 2 penetrates the top of the outer barrel 4 and is fixedly connected with a first pressing plate 1, side plates 12 are fixedly connected to the tops of two sides of the outer barrel 4, a limiting component for limiting the inner barrel 5 is arranged on the outer wall of the outer barrel 4, a control component for releasing the brake of the inner barrel 5 is arranged inside one of the side plates 12, the limiting component includes a clamping plate 8 slidably penetrating the outer wall of the outer barrel 4, a plurality of clamping grooves 7 clamped with the clamping plate 8 are vertically and equidistantly arranged on one side of the inner barrel 5, the clamping plate 8 and the clamping grooves 7 are better displayed in the drawing, the clearance between the clamping plate 8 and the clamping groove 7 is drawn to be larger, the clearance between the actual clamping plate 8 and the clamping groove 7 is smaller, one end of the clamping plate 8, which is far away from the outer cylinder 4, is fixedly connected with a limiting plate 9, two first tension springs 10 which are symmetrically arranged are fixedly connected between the limiting plate 9 and the outer cylinder 4, an inclined hole 3 is formed in the clamping plate 8 and is used for realizing the limiting function of the inner cylinder 5, the control component comprises a vertical plate 11 which penetrates through the top of a side plate 12 in a sliding manner, the top of the vertical plate 11 is fixedly connected with a second pressing plate 14, the same spring 13 is fixedly connected between the bottom of the second pressing plate 14 and the top of the side plate 12, the spring 13 is sleeved on the vertical plate 11 and is used for relieving the clamping state of the clamping plate 8 and the clamping groove 7 and is convenient for continuous use, the bottom of the vertical plate 11 is obliquely arranged and extends into the inclined hole 3, the inner wall of one side of the inclined hole 3, which is close to the limiting plate 9 is obliquely arranged, the bottom of the inclined hole 11 is abutted against the inner wall of one side of the inclined hole 3, which is close to the limiting plate 9, be convenient for promote cardboard 8, two second extension springs 15 that fixedly connected with symmetry set up between the top inner wall of urceolus 4 and the top of inner tube 5, cardboard 8 resilience of being convenient for, the bottom of curb plate 12 and the top of first clamp plate 1 all are provided with the slipmat, avoid the smooth injection failure that leads to of hand.

The working principle of the utility model is as follows: when the needle is used, the needle head is arranged on the needle cylinder 6, the forefinger and the middle finger of one hand hook the bottoms of the two side plates 12, the other hand holds the inner cylinder 5, the second pressing plate 14 is pressed, the second pressing plate 14 drives the vertical plate 11 to vertically move downwards and extrude the spring 13, the vertical plate 11 slides on the inner wall of the inclined hole 3 and can push the clamping plate 8 to transversely move, the clamping plate 8 drives the limiting plate 9 to transversely move and stretch the first tension spring 10, the clamping plate 8 and the clamping groove 7 are disengaged at the moment, the inner cylinder 5 vertically moves upwards under the action of the tension of the second tension spring 15, the hand holding the inner cylinder 5 slowly moves towards the outer cylinder 4 at the moment, the inner cylinder 5 drives the needle cylinder 6 and the piston rod 2 to slowly vertically move upwards, when the next clamping groove 7 moves to the position of the clamping plate 8, the second pressing plate 14 is directly loosened under the elastic force of the spring 13, the clamping plate 8 returns to the initial position under the elastic force of the first tension spring 10, then the clamping plate 8 is clamped with the next clamping groove 7 again, at the moment, the first pressing plate 1 is pressed by a thumb, the first pressing plate 1 drives the piston rod 2 to vertically move downwards, the piston rod 2 injects the reagent in the inner cylinder 5 to the brain of the mouse until the bottom of the first pressing plate 1 is abutted to the top of the outer cylinder 4, at the moment, the first pressing plate 1 cannot continuously move downwards (the distance between the clamping grooves 7 in the embodiment is set according to the moving distance of the piston rod 2 in the needle cylinder 6 when the liquid outlet amount of the needle cylinder 6 is 0.03 ml), at the moment, the injection amount of the reagent is close to 0.03ml, after the injection is finished, the thumb loosens the first pressing plate 1, when the injection is needed again, the second pressing plate 14 is pressed again in the same way, the operation can be repeated, the function of quantitatively injecting the reagent can be realized, the dosage of each injection is ensured to be kept consistent, and the accuracy of the experimental result is further improved, when extracting the reagent, the index finger and the middle finger of one hand hook the bottoms of the two side plates 12, the other hand holds the inner cylinder 5, presses the second pressing plate 14 to push the first pressing plate 1 to move the piston rod 2 to the bottommost part of the needle cylinder 6, then inserts a needle (not shown in the figure) on the needle cylinder 6 into the reagent bottle, then pulls the side plate 12 upwards to drive the piston rod 2 to move upwards, so that the reagent can be extracted into the needle cylinder 6, when the clamping plate 8 is positioned in the clamping groove 7 at the top, the second pressing plate 14 is released, the plate 8 is clamped with the clamping groove 7 to brake the inner cylinder 5, before injection, the first pressing plate 1 is pressed downwards to enable the bottom of the first pressing plate 1 to be abutted to the top of the outer cylinder 4.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and equivalent alternatives or modifications according to the technical solution of the present invention and the inventive concept thereof should be covered by the scope of the present invention.

Claims

1. The utility model provides a syringe for mouse brain benefit attacks poison, includes urceolus (4), its characterized in that, the inner wall sliding connection of urceolus (4) has inner tube (5), the bottom of inner tube (5) extends to the below of urceolus (4), fixedly connected with cylinder (6) is run through to the inside of inner tube (5), the inside of cylinder (6) is provided with piston rod (2), the top of piston rod (2) is run through the top of urceolus (4) and first clamp plate (1) of fixedly connected with, the equal fixedly connected with curb plate (12) in both sides top of urceolus (4), the outer wall of urceolus (4) is provided with and is used for carrying out spacing subassembly to inner tube (5), one of them the inside of curb plate (12) is provided with and is used for relieving the control assembly of inner tube (5) braking.

2. The syringe for mouse brain poison replenishing and attacking according to claim 1, wherein the limiting component comprises a clamping plate (8) which penetrates through the outer wall of the outer cylinder (4) in a sliding mode, a plurality of clamping grooves (7) which are clamped with the clamping plate (8) are formed in one side of the inner cylinder (5) in a vertical and equidistant mode, a limiting plate (9) is fixedly connected to one end, away from the outer cylinder (4), of the clamping plate (8), two first tension springs (10) which are symmetrically arranged are fixedly connected between the limiting plate (9) and the outer cylinder (4), and an inclined hole (3) is formed in the clamping plate (8).

3. The syringe used for mouse brain invigoration and attack according to claim 1, wherein the control component comprises a vertical plate (11) which penetrates through the top of the side plate (12) in a sliding manner, the top of the vertical plate (11) is fixedly connected with a second pressing plate (14), the same spring (13) is fixedly connected between the bottom of the second pressing plate (14) and the top of the side plate (12), and the vertical plate (11) is sleeved with the spring (13).

4. The injector for mouse brain poison compensation and attack according to claim 3, wherein the bottom of the vertical plate (11) is inclined and extends to the inside of the inclined hole (3), the inner wall of one side of the inclined hole (3) close to the limiting plate (9) is inclined, and the bottom of the vertical plate (11) is in contact with the inner wall of one side of the inclined hole (3) close to the limiting plate (9).

5. The syringe for mouse brain poison compensation and attack according to claim 1, wherein two second tension springs (15) which are symmetrically arranged are fixedly connected between the inner wall of the top of the outer cylinder (4) and the top of the inner cylinder (5).

6. The injector for mouse brain poison compensation and attack according to claim 1, wherein the bottom of the side plate (12) and the top of the first pressing plate (1) are provided with non-slip pads.