CN216550484U

CN216550484U - Macrophage changes bag divertor

Info

Publication number: CN216550484U
Application number: CN202123175764.9U
Authority: CN
Inventors: 袁源; 丁平
Original assignee: Sichuan Kantsai Medical Technology Co ltd
Current assignee: Sichuan Kantsai Medical Technology Co ltd
Priority date: 2021-12-16
Filing date: 2021-12-16
Publication date: 2022-05-17
Anticipated expiration: 2031-12-16

Abstract

The application provides a macrophage changes bag divertor belongs to cell culture utensil technical field. The macrophage bag-turning fluid director comprises a clamping component and a fluid directing component, wherein the clamping component comprises a base, a bidirectional screw rod, a moving block, a fixing plate and a clamping piece, the base is provided with a groove, the flow guide component comprises a fixed block, a holding rod, a cell culture bag, a connector, an upright post and a flow guide hopper, the fixed block is fixedly connected with the top of the fixed plate, the holding rod penetrates through the fixed block in a sliding manner, the cell culture bag can be clamped and fixed by arranging the base, the bidirectional screw rod, the moving block, the fixing plate and the clamping piece, the application range can be adjusted to a certain degree according to the size of the cell culture bag, through setting up fixed block, holding up pole, cell culture bag, connector, stand and water conservancy diversion fill, can be stable convenient in fight connector and water conservancy diversion, and then make things convenient for personnel to shift the cell of cultivateing in the blake bottle to the cell culture bag in.

Description

Macrophage changes bag divertor

Technical Field

The application relates to the field of cell culture appliances, in particular to a macrophage bag-turning fluid director.

Background

Macrophages are one of three antigen presenting cells and are important cells involved in nonspecific and specific immunity. Their main functions are to phagocytize cellular debris and pathogens in the form of fixed or free cells, and to activate lymphocytes or other immune cells to respond to pathogens. Common for cell culture in laboratories are cell culture flasks, cell culture dishes, cell culture bags, and the like. When the culture solution is too large or the cost is saved, the cells need to be transferred to a culture bag for continuous culture.

At present to the mode of transfer culture cell in the culture bag, mostly once only the syringe draws the injection repeatedly, consumes manpower and time, and the cell bag is difficult fixed, and long-time repetitive operation makes mistakes easily and leads to omitting, so not only the cost of wasting, still pollutes the culture cell liquid easily.

SUMMERY OF THE UTILITY MODEL

In order to remedy the above deficiencies, the present application provides a macrophage turning pocket deflector, which aims to improve the problems mentioned in the background art.

The embodiment of the application provides a macrophage turning bag fluid director which comprises a clamping assembly and a fluid directing assembly.

The clamping assembly comprises a base, two-way lead screws, two moving blocks, a fixing plate and a clamping piece, wherein the base is provided with a groove, the two-way lead screws are rotatably arranged in the groove, one end of each two moving block extends to the outside, the two moving blocks are respectively in threaded sleeve joint with the two sides of each two-way lead screw, the fixing plate is fixedly connected to the tops of the two moving blocks, and the clamping piece is arranged on one side of the fixing plate.

The water conservancy diversion subassembly includes the fixed block, holds up pole, cell culture bag, connector, stand and water conservancy diversion fill, fixed block fixed connection in the fixed plate top, hold up the pole and slide and run through the fixed block, the cell culture bag passes through the clamping piece install in fixed plate one side, the connector intercommunication set up in cell culture bag top, hold up the pole butt in connector one side, stand fixed connection in base one side, the water conservancy diversion fill run through set up in the stand top, just the water conservancy diversion fill bottom extends into in the connector.

In the above-mentioned realization process, through setting up base, two-way lead screw, movable block, fixed plate and clamping piece, can fix the cell culture bag centre gripping to can adjust application scope to a certain extent according to the size of cell culture bag, fight through setting up the fixed block, holding up pole, cell culture bag, connector, stand and water conservancy diversion, can be stable convenient in fight connector and water conservancy diversion, and then make things convenient for personnel to shift the cell of cultivateing in the blake bottle to the cell culture bag in.

In a specific embodiment, the clamping member includes a clamping plate disposed at an end of the connecting plate, a connecting plate hinged to one side of the fixing plate, and a spring disposed between the connecting plate and the fixing plate.

In the implementation process, the culture bag can be clamped and fixed quickly and stably by arranging the clamping plate, the connecting plate and the spring.

In a specific embodiment, a rubber pad is arranged on one side of the clamping plate close to the fixing plate.

In the implementation process, the rubber pad is arranged, so that the abrasion to the cell band is reduced, and the cell band is not easy to slip.

In a specific embodiment, the fixing block is provided with a positioning knob in a penetrating manner, and the positioning knob abuts against one side of the supporting rod.

In the implementation process, the positioning knob is arranged, so that the position of the holding rod is favorably positioned and stabilized, and the position of the connector is further stabilized.

In a specific embodiment, one end of the support rod is fixedly connected with a support block, and the support block is provided with an arc groove.

In the implementation process, the supporting block is arranged and the arc groove is formed, so that the connector is stably fixed without shaking and shifting.

In a specific embodiment, a pull ring is fixedly connected to one end of the holding rod away from the holding block.

In the implementation process, the holding rod is convenient to operate by arranging the pull ring.

In a specific implementation scheme, the base is provided with a limiting sliding groove communicated with the groove, the bottom of the moving block is fixedly connected with a limiting sliding block, and the limiting sliding block is slidably arranged in the limiting sliding groove.

In the implementation process, the limiting sliding block slides in the limiting sliding groove and is used for limiting the rotation of the moving block, and the rotation of the moving block along with the rotation of the bidirectional lead screw is avoided.

In a specific embodiment, a hand wheel is fixedly connected to one end of the bidirectional screw rod extending outside.

In the implementation process, the hand wheel is arranged and used for driving the bidirectional screw rod to rotate.

In a specific embodiment, the upright post is provided with a jack, and the flow guide bucket is inserted into the jack.

In the implementation process, the guide buckets with different specifications can be replaced by the mode of arranging the jacks for placing the guide buckets, so that the application range is widened.

In a specific embodiment, the bottom of the base is trapezoidal, and the bottom of the base is provided with anti-skid lines.

Drawings

In order to more clearly explain the technical solutions of the embodiments of the present application, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present application and therefore should not be considered as limiting the scope, and that for those skilled in the art, other related drawings can be obtained from these drawings without inventive effort.

FIG. 1 is a schematic structural diagram of a macrophage turning bag fluid director provided by an embodiment of the application;

FIG. 2 is a schematic structural diagram of a clamping assembly provided in an embodiment of the present application;

fig. 3 is a schematic structural diagram of a flow guide assembly according to an embodiment of the present disclosure;

FIG. 4 is a schematic view of a clamp according to an embodiment of the present disclosure;

FIG. 5 is a schematic structural view of a support block according to an embodiment of the present disclosure;

fig. 6 is a schematic structural diagram of a pillar according to an embodiment of the present application.

In the figure: 100-a clamping assembly; 110-a base; 111-grooves; 112-a limit chute; 120-bidirectional lead screw; 121-hand wheel; 130-a moving block; 131-a limiting slide block; 140-a fixed plate; 150-a clamping member; 151-clamping plate; 1511-rubber pad; 152-a connecting plate; 153-a spring; 200-a flow guide assembly; 210-fixed block; 211-positioning knob; 220-holding rod; 221-a support block; 222-arc groove; 223-a pull ring; 230-cell culture bags; 240-connecting head; 250-upright column; 251-a jack; 260-diversion hopper.

Detailed Description

The technical solutions in the embodiments of the present application will be described below with reference to the drawings in the embodiments of the present application.

To make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are some embodiments of the present application, but not all embodiments. All other embodiments obtained by a person of ordinary skill in the art without any inventive work based on the embodiments in the present application are within the scope of protection of the present application.

Referring to fig. 1-6, the present application provides a macrophage turning pouch deflector which includes a clamping assembly 100 and a deflector assembly 200.

Referring to fig. 1, 2, 3 and 4, the clamping assembly 100 includes a base 110, a bidirectional lead screw 120, two moving blocks 130, a fixing plate 140 and a clamping member 150, the base 110 is provided with a groove 111, the bidirectional lead screw 120 is rotatably disposed in the groove 111 and one end of the bidirectional lead screw extends to the outside, the two moving blocks 130 are disposed in two, the two moving blocks 130 are respectively sleeved on two sides of the bidirectional lead screw 120 in a threaded manner, the fixing plate 140 is fixedly connected to the top of the moving blocks 130, the fixing plate 140 is bolted or welded to the moving blocks 130, the clamping member 150 is disposed on one side of the fixing plate 140, it should be noted that the base 110 is provided with a limiting sliding chute 112 communicated with the groove 111, the bottom of the moving blocks 130 is fixedly connected with a limiting slider 131, the moving blocks 130 are integrally formed with a limiting slider 131, the limiting slider 131 is slidably disposed in the limiting sliding chute 112, and is configured to slide in the limiting sliding chute 112 for limiting the rotation of the moving blocks 130, preventing it from rotating as the bidirectional screw 120 rotates.

In this embodiment, the clamping member 150 includes a clamping plate 151, a connecting plate 152 and a spring 153, the clamping plate 151 is disposed at an end of the connecting plate 152, the clamping plate 151 is integrally formed at the connecting plate 152, the connecting plate 152 is hinged to one side of the fixing plate 140, the spring 153 is disposed between the connecting plate 152 and the fixing plate 140, the clamping plate 151, the connecting plate 152 and the spring 153 are disposed to clamp and fix the culture bag rapidly and stably, it should be noted that a rubber pad 1511 is disposed on one side of the clamping plate 151 close to the fixing plate 140, and the rubber pad 1511 is disposed to reduce wear to the cell band and prevent slipping.

In some embodiments, a hand wheel 121 is fixedly connected to one end of the bidirectional screw 120 extending to the outside, and the hand wheel 121 is arranged to drive the bidirectional screw 120 to rotate.

In some embodiments, the bottom of the base 110 is trapezoidal, and the bottom of the base 110 is provided with anti-slip lines.

Referring to fig. 1, 2, 3, 5 and 6, the flow guiding assembly 200 includes a fixing block 210, a holding rod 220, a cell culture bag 230, a connector 240, a column 250 and a flow guiding bucket 260, the fixing block 210 is fixedly connected to the top of the fixing plate 140, the fixing block 210 is bolted or welded to the fixing plate 140, the holding rod 220 slidably penetrates through the fixing block 210, the cell culture bag 230 is mounted on one side of the fixing plate 140 through a clamping member 150, the connector 240 is communicatively disposed on the top of the cell culture bag 230, the holding rod 220 abuts against one side of the connector 240, the column 250 is fixedly connected to one side of the base 110, the flow guiding bucket 260 penetrates through the top of the column 250, and the bottom of the flow guiding bucket 260 extends into the connector 240.

In this embodiment, the fixed block 210 runs through and is provided with the positioning knob 211, positioning knob 211 butt in holding pole 220 one side, through setting up positioning knob 211, be favorable to the location to stabilize the position of holding pole 220, and then stabilize the position of connector 240, it needs to explain, hold pole 220 one end fixedly connected with and support piece 221, support piece 221 and seted up arc groove 222, support piece 221 and set up arc groove 222 through setting up, be used for stabilizing fixed connector 240 and not rocking the skew.

In some embodiments, a pull ring 223 is fixedly connected to an end of the support rod 220 away from the support block 221, and the support rod 220 is convenient to operate by providing the pull ring 223.

In this embodiment, the column 250 is provided with the insertion hole 251, the guide hopper 260 is inserted into the insertion hole 251, and the guide hopper 260 with different specifications can be replaced by arranging the insertion hole 251 for placing the guide hopper 260, so that the application range is widened.

The operating principle of the macrophage bag-turning fluid director is as follows: when the cell culture bag clamping device is used, according to the size of a cell culture bag 230, a hand wheel 121 is rotated, the hand wheel 121 drives a bidirectional screw 120 to rotate, the bidirectional screw 120 drives moving blocks 130 to move, the two moving blocks 130 move close to each other, a fixing plate 140 drives a fixing plate 140 to move, then a connecting plate 152 is pressed and rotated, the connecting plate 152 extrudes a spring 153 and drives a clamping plate 151 to be far away from the fixing plate 140, one side edge of the cell culture bag 230 is placed between the clamping plate 151 and the fixing plate 140, the connecting plate 152 is loosened, the spring 153 elastically restores to push the connecting plate 152 to rotate, the connecting plate 152 drives the clamping plate 151 and a rubber pad 1511 to clamp one side edge of the cell culture bag 230, then another clamping piece 150 is used for clamping the other side edge of the cell culture bag 230, a connector 240 is centered, a holding rod 220 is pushed, the holding rod 220 drives a holding block 221 to move, the holding blocks 221 on the two sides are close to the holding and centering connector 240, a flow guide hopper 260 is placed in and extends into the connector 240 through an insertion hole 251, can transfer the macrophage culture solution in the blake bottle to the cell culture bag 230 in, it is stable firm in the transfer process, avoid long-time repetitive operation to take place the error and cause the condition of omitting or polluting.

The above description is only an example of the present application and is not intended to limit the scope of the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application. It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.

The above description is only for the specific embodiments of the present application, but the scope of the present application is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present application, and shall be covered by the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims

1. A macrophage turning bag fluid director is characterized by comprising

The clamping assembly (100) comprises a base (110), a bidirectional lead screw (120), a moving block (130), a fixing plate (140) and a clamping element (150), wherein the base (110) is provided with a groove (111), the bidirectional lead screw (120) is rotatably arranged in the groove (111) and one end of the bidirectional lead screw extends to the outside, the moving block (130) is provided with two blocks, the two moving blocks (130) are respectively sleeved on two sides of the bidirectional lead screw (120) in a threaded manner, the fixing plate (140) is fixedly connected to the top of the moving block (130), and the clamping element (150) is arranged on one side of the fixing plate (140);

the flow guide component (200), the flow guide component (200) comprises a fixed block (210), a support rod (220), a cell culture bag (230), a connector (240), a column (250) and a flow guide hopper (260), the fixed block (210) is fixedly connected to the top of the fixed plate (140), the holding rod (220) penetrates through the fixed block (210) in a sliding manner, the cell culture bag (230) is attached to one side of the fixing plate (140) by the clamp (150), the connector (240) is communicated with the top of the cell culture bag (230), the holding rod (220) is abutted against one side of the connecting head (240), the upright post (250) is fixedly connected to one side of the base (110), the flow guide hopper (260) is arranged at the top of the upright post (250) in a penetrating way, and the bottom of the flow guide hopper (260) extends into the connecting head (240).

2. The macrophage turning bag fluid director according to claim 1, wherein the clamping member (150) comprises a clamping plate (151), a connecting plate (152) and a spring (153), the clamping plate (151) is arranged at the end of the connecting plate (152), the connecting plate (152) is hinged at one side of the fixing plate (140), and the spring (153) is arranged between the connecting plate (152) and the fixing plate (140).

3. The macrophage turning bag fluid director according to claim 2, wherein a rubber pad (1511) is arranged on one side of the clamping plate (151) close to the fixing plate (140).

4. The macrophage turning bag fluid director according to claim 1, wherein a positioning knob (211) is penetratingly arranged on the fixing block (210), and the positioning knob (211) abuts against one side of the holding rod (220).

5. The macrophage turning bag fluid director according to claim 1, wherein one end of the supporting rod (220) is fixedly connected with a supporting block (221), and the supporting block (221) is provided with an arc groove (222).

6. The macrophage turning bag fluid director according to claim 5, wherein a pull ring (223) is fixedly connected to one end of the holding rod (220) far away from the holding block (221).

7. The macrophage turning bag fluid director according to claim 1, wherein the base (110) is provided with a limiting sliding groove (112) communicated with the groove (111), a limiting sliding block (131) is fixedly connected to the bottom of the moving block (130), and the limiting sliding block (131) is slidably disposed in the limiting sliding groove (112).

8. The macrophage turning bag fluid director according to claim 1, wherein a hand wheel (121) is fixedly connected to one end of the bidirectional screw rod (120) extending outside.

9. The macrophage turning bag fluid director according to claim 1, wherein the column (250) is provided with a plug hole (251), and the fluid director (260) is inserted into the plug hole (251).

10. The macrophage turning bag fluid director according to claim 1, wherein the bottom of the base (110) is trapezoidal, and the bottom of the base (110) is provided with anti-skid veins.