CN216537281U - Protein precipitation and filtration device - Google Patents

Protein precipitation and filtration device Download PDF

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Publication number
CN216537281U
CN216537281U CN202122641204.1U CN202122641204U CN216537281U CN 216537281 U CN216537281 U CN 216537281U CN 202122641204 U CN202122641204 U CN 202122641204U CN 216537281 U CN216537281 U CN 216537281U
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pipeline
box body
protein precipitation
protein
filtration
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CN202122641204.1U
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Chinese (zh)
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占远
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Suzhou Fangda New Drug Development Co ltd
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Suzhou Fangda New Drug Development Co ltd
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Abstract

The utility model provides a protein precipitation and filtration device, which belongs to the technical field of protein processing and comprises a first box body, a second box body, a filtration part, a suction part and a driving part, wherein one side of the first box body is connected with a first pipeline, one side of the second box body is connected with a second pipeline, the filtration part is arranged between the first pipeline and the second pipeline and is detachably connected with the first pipeline and the second pipeline, the suction part and the driving part are both arranged in the second box body, and the driving part is used for driving the suction part to move along the interior of the second box body so as to suck protein liquid in the first box body into the second box body from the first pipeline, the filtration part and the second pipeline. Compared with the prior art, the embodiment of the utility model can realize the suction filtration of the protein liquid, can greatly improve the filtration efficiency of the protein liquid, shortens the filtration process of the protein liquid, and has the advantage of good filtration effect.

Description

Protein precipitation filter equipment
Technical Field
The utility model belongs to the technical field of protein processing, and particularly relates to a protein precipitation and filtration device.
Background
At present, protein precipitation is an effective means for separating protein liquid from stock solution, and since the stock solution contains more impurities and large particulate matters, the impurities and the large particulate matters are easy to precipitate together with the protein liquid after the protein liquid is precipitated, so that the protein liquid needs to be filtered to remove the impurities and the large particulate matters.
In the prior art, most of removing means for impurities and large particulate matters place protein liquid on the upper portion of a filter screen, the protein liquid passes through the filter screen under the action of gravity of the protein liquid, the impurities and the large particulate matters are retained on the upper portion of the filter screen, and purification of the protein liquid is realized.
Disclosure of Invention
In view of the above-mentioned deficiencies of the prior art, an embodiment of the present invention provides a protein precipitation and filtration apparatus.
In order to solve the technical problems, the utility model provides the following technical scheme:
a protein precipitation filtering device comprises a first box body, a second box body, a filtering part, a suction part and a driving part,
one side of the first box body is connected with a first pipeline, one side of the second box body is connected with a second pipeline,
the filtering part is arranged between the first pipeline and the second pipeline and is detachably connected with the first pipeline and the second pipeline,
the suction part and the driving part are arranged in the second box body, the driving part is used for driving the suction part to move along the inside of the second box body so as to suck the protein liquid in the first box body into the second box body from the first pipeline, the filtering part and the second pipeline, and the filtering part can filter the protein liquid at the moment.
As a further improvement of the utility model: the filtering part comprises a connecting pipe and a conical filter screen arranged in the connecting pipe,
the awl point orientation of toper filter screen first pipeline, the one end that first box was kept away from to first pipeline and the one end that the second box was kept away from to the second pipeline all is provided with the sealing, the connecting pipe both ends link to each other with the sealing butt that corresponds respectively.
As a further improvement of the utility model: the sealing part comprises a sleeve and a sealing piece arranged on one side, facing the connecting pipe, of the sleeve, and the sleeve is in threaded fit with the corresponding first pipeline and the second pipeline.
As a further improvement of the utility model: the sealing element is a rubber ring or a silica gel ring.
As a still further improvement of the utility model: the suction part comprises a piston plate, an extension rod and a rack,
the piston plate is movably arranged in the second box body, the extension rod is fixedly arranged at one side of the piston plate, the rack is fixedly arranged on the side wall of the extension rod,
the driving part comprises a motor and a gear connected to the output end of the motor, and the gear is meshed with the rack.
As a still further improvement of the utility model: and a flexible sealing layer is annularly arranged on the side wall of the piston plate.
As a still further improvement of the utility model: the flexible sealing layer is a rubber layer or a silica gel layer.
Compared with the prior art, the utility model has the beneficial effects that:
in the embodiment of the utility model, when the protein liquid filtering device is used, the protein liquid is injected into the first box body, the driving part drives the suction part to move along the interior of the second box body, the negative pressure generated when the suction part moves can suck the protein liquid in the first box body into the second box body from the first pipeline, the filtering part and the second pipeline, and when the protein liquid flows through the filtering part, impurities and large granular substances in the protein liquid can be filtered to ensure the purity of the protein liquid entering the second box body.
Drawings
FIG. 1 is a schematic view of a protein precipitation filtration apparatus;
FIG. 2 is a schematic view showing the construction of a suction part in a protein precipitation filtration apparatus;
FIG. 3 is an enlarged view of area A of FIG. 1;
in the figure: 1-a first box body, 11-a first pipeline, 2-a filtering part, 21-a connecting pipe, 22-a conical filter screen, 3-a second box body, 31-a second pipeline, 4-a suction part, 41-a piston plate, 42-an extension rod, 43-a rack, 44-a flexible sealing layer, 5-a driving part, 6-a sealing part, 61-a sleeve and 62-a sealing part.
Detailed Description
The technical solution of the present patent will be described in further detail with reference to the following embodiments.
Reference will now be made in detail to embodiments of the present patent, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present patent and are not to be construed as limiting the present patent.
Referring to the drawings, the present embodiment provides a protein precipitation and filtration apparatus, which includes a first box 1, a second box 3, a filtration part 2, a suction part 4 and a driving part 5, one side of the first box body 1 is connected with a first pipeline 11, one side of the second box body 3 is connected with a second pipeline 31, the filter part 2 is disposed between the first pipe 11 and the second pipe 31 and detachably connected to the first pipe 11 and the second pipe 31, the suction part 4 and the driving part 5 are both arranged inside the second box 3, the driving part 5 is used for driving the suction part 4 to move along the inside of the second box 3, so as to suck the protein liquid in the first box 1 from the first pipeline 11, the filter part 2 and the second pipeline 31 to the second box 3, and at this time, the filter part 2 can filter the protein liquid.
During the use, pour into first box 1 with protein liquid inside, drive portion 4 through drive division 5 and move along second box 3 is inside, the negative pressure that produces when suction portion 4 removes can be with the inside protein liquid of first box 1 from first pipeline 11, filter house 2 and second pipeline 31 suction to second box 3 inside, when protein liquid flows through filter house 2, debris and large granule material in the protein liquid can be filtered to guarantee to get into the purity of the inside protein liquid of second box 3.
Referring to fig. 3, in an embodiment, the filter portion 2 includes a connecting pipe 21 and a conical filter screen 22 disposed inside the connecting pipe 21, a conical tip of the conical filter screen 22 faces the first pipe 11, sealing portions 6 are disposed at both ends of the first pipe 11 far away from the first box 1 and the second pipe 31 far away from the second box 3, and two ends of the connecting pipe 21 are respectively connected to the corresponding sealing portions 6 in an abutting manner.
When the protein liquid flows through the inside of the connecting pipe 21, the protein liquid can act on the outer wall of the conical filter screen 22, impurities and large granular substances in the protein liquid can be blocked by the conical filter screen 22, the protein liquid can smoothly pass through the conical filter screen 22 to enter the inside of the second box body 3, and along with the continuous flow of the protein liquid, the impurities and the large granular substances on the outer wall of the conical filter screen 22 can be pushed to slide along the outer wall of the conical filter screen 22, so that the impurities and the large granular substances are gathered at an included angle between the conical filter screen 22 and the connecting pipe 21, the impurities and the large granular substances are prevented from being attached to the outer wall of the conical filter screen 22 all the time, and further the smooth flow of the subsequent protein liquid is influenced; by the provision of the seal portion 6, the sealed connection between the first tube 11, the second tube 31 and the connection tube 21 can be achieved to prevent leakage of the protein liquid.
Referring to fig. 3, in one embodiment, the sealing portion 6 includes a sleeve 61 and a sealing member 62 disposed on a side of the sleeve 61 facing the connecting pipe 21, and the sleeve 61 is threadedly engaged with the corresponding first pipe 11 and the second pipe 31.
When the device is installed, the connecting pipe 21 is placed between the first pipe 11 and the second pipe 31, the sleeve 61 is rotated, so that the sleeve 61 moves towards the connecting pipe 21 to drive the sealing element 62 to abut against the end of the connecting pipe 21, and further, the communication among the first pipe 11, the connecting pipe 21 and the second pipe 31 is realized.
In the above embodiments, the sealing member 62 is a rubber ring or a silicone ring, which is not limited herein.
Referring to fig. 1 and 2, in an embodiment, the suction part 4 includes a piston plate 41, an extension rod 42 and a rack 43, the piston plate 41 is movably disposed inside the second casing 3, the extension rod 42 is fixedly disposed at one side of the piston plate 41, the rack 43 is fixedly mounted on a side wall of the extension rod 42, the driving part 5 includes a motor and a gear connected to an output end of the motor, and the gear is engaged with the rack 43.
The gear is driven to rotate by the motor, the extension rod 42 is driven to move by the meshing action of the gear and the rack 43, the piston plate 41 is driven to move along the inside of the second box body 3, and when the piston plate 41 moves, protein liquid in the first box body 1 can be extracted to the inside of the second box body 3 from the first pipeline 11, the connecting pipe 21 and the second pipeline 31.
Referring to fig. 2, in one embodiment, the side wall of the piston plate 41 is surrounded by a flexible sealing layer 44, and the flexible sealing layer 44 is attached to the inner wall of the second casing 3.
By the arrangement of the flexible sealing layer 44, the piston plate 41 can be in close contact with the inner wall of the second box 3, so that protein liquid can be smoothly extracted when the piston plate 41 moves, and the sealing effect between the piston plate 41 and the second box 3 is improved.
In the above embodiment, the flexible sealing layer 44 may be a rubber layer, or may be a silicone layer, which is not limited herein.
In the embodiment of the utility model, when the protein liquid filtering device is used, the protein liquid is injected into the first box body 1, the suction part 4 is driven by the driving part 5 to move along the inside of the second box body 3, the negative pressure generated when the suction part 4 moves can suck the protein liquid in the first box body 1 from the first pipeline 11, the filtering part 2 and the second pipeline 31 into the second box body 3, and when the protein liquid flows through the filtering part 2, impurities and large granular substances in the protein liquid can be filtered to ensure the purity of the protein liquid entering the second box body 3.
Although the preferred embodiments of the present patent have been described in detail, the present patent is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present patent within the knowledge of those skilled in the art.

Claims (7)

1. A protein precipitation and filtration device is characterized by comprising a first box body, a second box body, a filtration part, a suction part and a driving part,
one side of the first box body is connected with a first pipeline, one side of the second box body is connected with a second pipeline,
the filtering part is arranged between the first pipeline and the second pipeline and is detachably connected with the first pipeline and the second pipeline,
the suction part and the driving part are arranged in the second box body, the driving part is used for driving the suction part to move along the inside of the second box body so as to suck the protein liquid in the first box body into the second box body from the first pipeline, the filtering part and the second pipeline, and the filtering part can filter the protein liquid at the moment.
2. A protein precipitation filtration unit according to claim 1, wherein said filtration part comprises a connection pipe and a conical strainer disposed inside said connection pipe,
the awl point orientation of toper filter screen first pipeline, the one end that first box was kept away from to first pipeline and the one end that the second box was kept away from to the second pipeline all is provided with the sealing, the connecting pipe both ends link to each other with the sealing butt that corresponds respectively.
3. A protein precipitation filtration device according to claim 2 wherein said seal comprises a sleeve and a seal disposed on a side of said sleeve facing said connection tube, said sleeve being in threaded engagement with the respective first and second tubes.
4. A protein precipitation filtration unit according to claim 3 wherein said seal is a rubber ring or a silica gel ring.
5. The protein precipitation filtration unit of claim 1, wherein the suction portion comprises a piston plate, an extension rod, and a rack,
the piston plate is movably arranged in the second box body, the extension rod is fixedly arranged at one side of the piston plate, the rack is fixedly arranged on the side wall of the extension rod,
the driving part comprises a motor and a gear connected to the output end of the motor, and the gear is meshed with the rack.
6. A protein precipitation filter unit according to claim 5 wherein said piston plate side wall is provided with a flexible sealing layer.
7. A protein precipitation filtration unit according to claim 6, wherein said flexible sealing layer is a rubber layer or a silica gel layer.
CN202122641204.1U 2021-11-01 2021-11-01 Protein precipitation and filtration device Active CN216537281U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122641204.1U CN216537281U (en) 2021-11-01 2021-11-01 Protein precipitation and filtration device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122641204.1U CN216537281U (en) 2021-11-01 2021-11-01 Protein precipitation and filtration device

Publications (1)

Publication Number Publication Date
CN216537281U true CN216537281U (en) 2022-05-17

Family

ID=81570305

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202122641204.1U Active CN216537281U (en) 2021-11-01 2021-11-01 Protein precipitation and filtration device

Country Status (1)

Country Link
CN (1) CN216537281U (en)

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