CN216499233U - Gel preparation system based on bionic high-purity hypochlorous acid water - Google Patents
Gel preparation system based on bionic high-purity hypochlorous acid water Download PDFInfo
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- CN216499233U CN216499233U CN202123128256.5U CN202123128256U CN216499233U CN 216499233 U CN216499233 U CN 216499233U CN 202123128256 U CN202123128256 U CN 202123128256U CN 216499233 U CN216499233 U CN 216499233U
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Abstract
The utility model discloses a gel preparation system based on bionic high-purity hypochlorous acid water, and belongs to the technical field of biomedical materials. The system comprises a bionic high-purity hypochlorous acid water preparation system and a gel preparation system, wherein the bionic high-purity hypochlorous acid water preparation system is used for preparing high-purity hypochlorous acid, the generation mode of hypochlorous acid in human neutrophils is imitated, hydrogen peroxide and hydrochloric acid with certain concentration are used as raw materials, methyl rhenium trioxide is used as a catalyst to prepare a high-purity hypochlorous acid solution, and a reverse osmosis filter membrane filtration method is adopted to recover the methyl rhenium trioxide catalyst. The hydrogel is prepared in the gel preparation system.
Description
Technical Field
The utility model discloses a gel preparation system based on bionic high-purity hypochlorous acid water, and belongs to the technical field of biomedical materials.
Background
The immune system of the human body is resistant to the invasion of external pathogens, largely because it produces an effective and rapid bactericidal reaction by generating highly reactive chemical species, such as Reactive Oxygen Species (ROS). Mitochondrial membrane-bound reduced coenzyme II (hereinafter referred to as NADPH) is a major enzyme for ROS production. During neutrophil activation, respiration produces hydrogen peroxide (H)2O2) And activated Myeloperoxidase (MPO) in Cl-And H+In the presence of H2O2Converted to hypochlorous acid (HOCl).
The results of the quantitative analysis showed that 10 ten thousand activated neutrophils could produce about 2X 10 cells within 2h of incubation time-7mol hypochlorous acid. In actual production, hypochlorous acid is generally generated by diaphragm type electrolytic sodium chloride or diaphragm-free electrolytic hydrochloric acid, and because the reaction efficiency of an electrolytic cell is low and the risk of generating chlorate by peroxidation in the electrolytic process exists, the hypochlorous acid has the risk of cytotoxicity when being used for medical wound care or skin and mucous membrane disinfection.
In addition, in the application process of the hypochlorous acid, the liquid state can not realize the long-time sterilization effect of the hypochlorous acid, and after the hypochlorous acid forms a gel state, the hypochlorous acid can act on the part to be sterilized through slow release, so that the sterilization effect of the hypochlorous acid is improved.
Disclosure of Invention
In order to solve the problems in the prior art, the utility model aims to provide a gel preparation system based on bionic high-purity hypochlorous acid water, which realizes the preparation of hypochlorous acid water and the preparation of gel by simulating the generation mode of hypochlorous acid in a human body.
The technical scheme adopted by the utility model for solving the technical problems is as follows:
a gel preparation system based on bionic high-purity hypochlorous acid water comprises a bionic high-purity hypochlorous acid water preparation system and a gel preparation system; bionic high-purity hypochlorous acid water preparation system include:
a first storage tank for storing the mixed solution of hydrochloric acid and sodium chloride,
a second storage tank for the reaction liquid for storing the hydrogen peroxide liquid,
the first mixing unit for mixing the liquids in the first and second storage tanks of the reaction liquid with the purified water in the first mixing unit may be provided with a vortex mixer.
The catalytic unit is used for carrying out methyl rhenium trioxide catalytic reaction on the product prepared by the first mixing unit;
the gel preparation system comprises: and the second mixing unit is used for mixing the product prepared by the catalytic unit with a gelling agent in the second mixing unit to obtain gel, and the mixing can be realized by a vortex mixer.
Preferably, the catalytic unit comprises a first-stage reverse osmosis filtering device and a catalytic reaction cavity which are connected from top to bottom.
In one embodiment, the catalytic unit further comprises a secondary reverse osmosis filtering device which is arranged behind the catalytic reaction cavity.
As another embodiment, the gel preparation system also comprises a buffer unit which is connected before the second mixing unit and is used for performing acid-base regulation and buffering on the product prepared by the catalytic unit
Compared with the background art, the utility model has the beneficial effects that:
1) the bionic high-purity hypochlorous acid water preparation system can simulate the generation mode of hypochlorous acid in a human body and generate hypochlorous acid water with higher purity and safety;
2) the prepared hypochlorous acid hydrogel can slowly generate hypochlorous acid for a long time so as to continuously play the roles of sterilization and biofilm resistance.
Drawings
Fig. 1 is a schematic view of an embodiment of the present invention.
In the figure, 1, a first reaction liquid storage tank 2, a second reaction liquid storage tank 3, a first peristaltic pump 4, a second peristaltic pump 5, a first proportional electromagnetic valve 6, a second proportional electromagnetic valve 7, a purified water input port 8, a first mixing unit 9, a first-stage reverse osmosis filtering device 10, a catalytic reaction cavity 12 and a second-stage reverse osmosis filtering device are adopted.
Detailed Description
Unless otherwise indicated, the following terms used in the present specification and claims have the definitions given below. It is noted that the use of the singular terms "a" and "an" in this specification and in various claims is intended to cover one or more than one of the recited items, such as at least one, at least two, or at least three, and not to imply that there is only a single recited item. In addition, the open-ended terms such as "include", "have", and the like used in each claim of the present application indicate combinations of components or elements described in the claim, and do not exclude other components or elements not specified in the claim. It should also be noted that the term "or" is generally also inclusive of "and/or" in a sense unless the content clearly dictates otherwise. The terms "about" and "substantially" as used in the specification and claims are intended to modify any slight variations that do not materially alter the spirit of the utility model.
Example 1
The embodiment provides a gel preparation system based on bionic high-purity hypochlorous acid water, and in the following embodiment, during specific experiments, the schematic flow diagram of the device is shown in figure 1, the mixing of hydrogen peroxide, sodium chloride, hydrochloric acid and purified water is completed in a first mixing unit 8, a first reaction liquid storage tank 1 is a stored hydrochloric acid + sodium chloride mixed solution, a second reaction liquid storage tank 2 is used for storing hydrogen peroxide, a first peristaltic pump 3 and a second peristaltic pump 4 are respectively arranged on two water outlet pipelines for controlling flow, a first proportional electromagnetic valve 5 and a second proportional electromagnetic valve 6 are respectively arranged in sequence for controlling the mixing proportion and are communicated with a purified water inlet 7, a flowmeter is arranged on the pipeline after the mixing of three branches for controlling the total flow of the mixture and are finally converged into the first mixing unit 8, then catalytic reaction is carried out in a catalytic unit, the filtration is carried out through a primary reverse osmosis filtering device 9, then, catalytic reaction is carried out in the catalytic reaction cavity 10, methyl rhenium trioxide is loaded in the catalytic reaction cavity 10, the methyl rhenium trioxide is intercepted and recovered through the secondary reverse osmosis filtering device 12, and finally, the high-purity hypochlorous acid water is prepared. The design of the system is inspired by the mechanism of generating hypochlorous acid by the immune system of a human body and is skillfully simulated.
The prepared high-purity hypochlorous acid water passes through a buffering unit and a second mixing unit and is used for mixing the product prepared by the catalytic unit with a gelling agent in the second mixing unit to obtain gel. Wherein, the buffering unit is used for adjusting the pH value of the system, the buffering is kept stable, some pH regulators, buffers and the like can be added, and finally, the gel is prepared in the second mixing unit, and the gel is usually added and stirred at normal temperature.
Claims (4)
1. A gel preparation system based on bionic high-purity hypochlorous acid water, which is characterized in that,
the system comprises a bionic high-purity hypochlorous acid water preparation system and a gel preparation system; bionic high-purity hypochlorous acid water preparation system include:
a first storage tank for storing the mixed solution of hydrochloric acid and sodium chloride,
a second storage tank for the reaction liquid for storing the hydrogen peroxide liquid,
a first mixing unit for mixing the liquids in the first and second storage tanks of the reaction liquid with the purified water in the first mixing unit,
the catalytic unit is used for carrying out methyl rhenium trioxide catalytic reaction on the product prepared by the first mixing unit;
the gel preparation system comprises: and the second mixing unit is used for mixing the product prepared by the catalytic unit with a gelling agent in the second mixing unit to obtain gel.
2. The system for preparing gel based on bionic high-purity hypochlorous acid water according to claim 1, wherein the catalytic unit comprises a first-stage reverse osmosis filtering device and a catalytic reaction cavity which are connected from top to bottom.
3. The biomimetic high-purity hypochlorous acid water based gel preparation system of claim 2, wherein the catalytic unit further comprises a secondary reverse osmosis filtration device disposed after the catalytic reaction chamber.
4. The biomimetic high-purity hypochlorous acid water-based gel preparation system of claim 1, further comprising a buffering unit connected to the second mixing unit for acid-base conditioning and buffering the product prepared by the catalytic unit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123128256.5U CN216499233U (en) | 2021-12-14 | 2021-12-14 | Gel preparation system based on bionic high-purity hypochlorous acid water |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123128256.5U CN216499233U (en) | 2021-12-14 | 2021-12-14 | Gel preparation system based on bionic high-purity hypochlorous acid water |
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| CN216499233U true CN216499233U (en) | 2022-05-13 |
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| CN202123128256.5U Active CN216499233U (en) | 2021-12-14 | 2021-12-14 | Gel preparation system based on bionic high-purity hypochlorous acid water |
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2021
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