CN216247999U

CN216247999U - New coronavirus antigen detection kit

Info

Publication number: CN216247999U
Application number: CN202122633632.XU
Authority: CN
Inventors: 郭敏; 翟雨萌; 樊智伟
Original assignee: Kangma Healthcode Shanghai Biotech Co Ltd
Current assignee: Kangma Shanghai Marine Technology Co ltd; Kangma Healthcode Shanghai Biotech Co Ltd
Priority date: 2021-10-31
Filing date: 2021-10-31
Publication date: 2022-04-08
Anticipated expiration: 2031-10-31

Abstract

The utility model discloses a new coronavirus antigen detection kit, which comprises a box body, wherein one side of the box body is hinged with a box cover suitable for opening and closing; the kit comprises a box body and a first swab accommodating groove, wherein the box body comprises a thin half part and a thick half part, a reagent groove is formed in the inner bottom wall of the thick half part, and the middle of the short side wall of the thick half part adjacent to the reagent groove is provided with the first swab accommodating groove; a test paper fixing structure and an observation window are fixedly arranged on the box cover, test paper is fixedly arranged on the test paper fixing structure, the position of a sampling part of the test paper corresponds to the position of the reagent groove, and the position of a color development part of the test paper corresponds to the position of the observation window; the first swab receiving channel is adapted to receive a stem portion of a swab, and the reagent channel is adapted to receive a sample portion of a swab. The whole process for antigen detection is carried out in the same container, and samples do not need to be transferred and are not easy to be polluted, so that the detection accuracy is ensured; can not leak and prevent cross infection.

Description

New coronavirus antigen detection kit

Technical Field

The utility model belongs to the technical field of biological detection, and particularly relates to a novel coronavirus antigen detection kit.

Background

At present, based on test paper and detect reagent's disposable portable self-service new corona virus detection device generally comprises upper and lower two apron, accompanies the test paper in the middle of two apron, and the upper cover plate middle part is equipped with the observation window, can observe the testing result, and the lower part sets up reagent drip mouth. During detection, a plurality of split components are required to be matched, a sample on the swab is firstly eluted into a reagent in the elution tube, and then the reagent in the elution tube is dripped onto test paper in the detection kit, so that the whole detection process can be completed.

The reagent kit with the split structure has the following defects and shortcomings in operation: first, the sample is susceptible to contamination during transfer from the elution tube to the test kit, thereby affecting the accuracy of the test. Secondly, leakage is easy to occur in the sample transfer process, cross infection of experimenters and related workers is caused, public health safety problems are caused, and great potential safety hazards exist. Third, because of the inconvenience of distinguishing the same samples during the testing process, a subject who is prone to misplacing or confusing samples during manual handling may appear: the swab sample is labeled with a subject A, the elution tube is labeled with another subject (B), and the detection kit is labeled with a third person (C), so that the detection kit has high error probability due to operation errors or errors.

Disclosure of Invention

The utility model aims to provide a novel coronavirus antigen detection kit to solve the defects mentioned in the background technology.

In order to realize the purpose, the new coronavirus antigen detection kit comprises a box body, wherein one side of the box body is hinged with a box cover suitable for opening and closing; the kit comprises a box body and a first swab accommodating groove, wherein the box body comprises a thin half part and a thick half part, a reagent groove is formed in the inner bottom wall of the thick half part, and the middle of the short side wall of the thick half part adjacent to the reagent groove is provided with the first swab accommodating groove; a test paper fixing structure and an observation window are fixedly arranged on the box cover, test paper is fixedly arranged on the test paper fixing structure, the position of a sampling part of the test paper corresponds to the position of the reagent groove, and the position of a color development part of the test paper corresponds to the position of the observation window; the first swab receiving channel is adapted to receive a stem portion of a swab, and the reagent channel is adapted to receive a sample portion of a swab.

Further, the bottom surface of the reagent well is a downward slope surface inclined in the direction of the thin half portion.

Further, the end of the reagent tank is connected with a slope groove for receiving the reagent overflowing from the reagent tank.

Further, a cover plate covers the upper portion of the reagent groove, a swab through hole and a test paper through groove are formed in the cover plate, the position of the swab through hole corresponds to that of the reagent groove, and the position of the test paper through groove corresponds to that of the slope groove; the upper surface of the cover plate is flush with the inner surface of the thin half.

Furthermore, a bulge part is arranged between the swab through hole and the test paper through groove, and the edge of the bulge part is chamfered.

Further, the bottom of the cover plate is provided with a bulge buckled with the reagent groove, and the opposite surface of the bulge is a second swab receiving groove suitable for receiving the rod part of the swab.

Furthermore, a plurality of fixing columns are fixedly arranged at the bottom of the cover plate, a plurality of fixing holes are formed in the periphery of the reagent tank, and the fixing columns are embedded in the fixing holes in a one-to-one correspondence mode.

Furthermore, at least one liquid blocking strip is fixedly arranged on the inner surface of the thin half part.

Further, the test paper fixing structure comprises two pairs of test paper fixing buckles and test paper limiting grooves, the test paper is clamped in each pair of fixing buckles, and the tail of the test paper is abutted to the test paper limiting grooves.

Furthermore, the test paper fixing structure further comprises at least one test paper support bar, and the test paper support bar is suitable for tilting the head of the test paper.

Furthermore, a clamping piece is arranged on the outer side wall of the box body, and at least one clamping strip is arranged on the inner side wall; the outer side edge of the box cover is provided with a buckle, and the edge of the inner surface of the box cover is provided with at least one clamping groove; the buckle is suitable for being buckled with the clamping piece, and the clamping strips are buckled with the clamping grooves in a one-to-one correspondence mode.

Compared with the prior art, the utility model has the following beneficial effects:

1. the whole detection process is carried out in the same container, the sample does not need to be transferred, the sample is not easy to be polluted, and the detection accuracy is ensured; leakage is avoided, and cross infection is prevented; meanwhile, the operation steps are reduced, the operation difficulty is reduced, and people without related detection experience can quickly get on hand.

2. The detected pollutants such as the reagent, the test paper, the swab and the like are all concentrated together, so that the concentrated treatment of the pollutants is facilitated, the pollution and virus leakage hazards caused by respective discarding are reduced, and the environment-friendly and safe effects are achieved.

3. The steps of sampling, eluting and detecting are carried out in a detection kit, namely sampling and detection are carried out, so that sample mixing is reduced, and the situation that the detection object is worn by the Kangguan plum and the detection result is not matched is avoided.

Drawings

FIG. 1 is a schematic structural diagram of one embodiment of the present invention;

FIG. 2 is a schematic diagram of the internal structure of one embodiment of the present invention;

FIG. 3 is a schematic cross-sectional view of a reagent tank according to an embodiment of the present invention;

FIG. 4 is a schematic cross-sectional view of a reagent tank according to another embodiment of the present invention.

In the attached drawings, 1-box body; 2-cover plate; 3-a slope groove; 4-a fastener; 5-liquid blocking strip; 6-clamping strips; 7-a clamping groove; 8-box cover; 9-test paper support bars; 10-buckling; 11-a viewing window; 12-a test paper fixing buckle; 13-a reagent tank; 14-a fixation hole; 15-swab through hole; 16-test paper through grooves; 17-fixed column; 18-test paper limiting groove; 19-a first swab receiving channel; 20-a second swab receiving channel; 21-bulge; 22-test paper.

Detailed Description

The embodiments of the present invention are described below with reference to specific embodiments, and other advantages and effects of the present invention will be easily understood by those skilled in the art from the disclosure of the present specification. The utility model is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present invention.

As shown in fig. 1-2, one embodiment of the reagent kit for detecting a new coronavirus antigen of the present invention comprises a box body 1, wherein a box cover 8 suitable for opening and closing is hinged to one side of the box body 1; the box body 1 comprises a thin half part and a thick half part, wherein the inner bottom wall of the thick half part is provided with a reagent groove 13, and the middle part of the short side wall of the thick half part adjacent to the reagent groove 13 is provided with a first swab accommodating groove 19; a test paper fixing structure and an observation window 11 are fixedly arranged on the box cover 8, a test paper 22 is fixedly arranged on the test paper fixing structure, the position of a sampling part of the test paper 22 corresponds to the position of the reagent groove 13, and the position of a color development part of the test paper 22 corresponds to the position of the observation window 11; the first swab receiving channel 19 is adapted to receive a stem portion of a swab, and the reagent channel 13 is adapted to receive a sample portion of a swab. As is apparent from fig. 1, the left half of the cartridge body 1 is a thick half, and the right half is a thin half. After the reagent is dropped into the reagent tank 13, the sample part of the swab with the sample is inserted into the reagent tank 13, the rod part is placed in the first swab accommodating groove 19, the swab is manually rotated back and forth to elute the sample on the swab into the reagent, the box cover 8 is buckled on the box body 1, the test paper 22 is immersed into the reagent, and the detection result is observed through the observation window 11. The eluted antigen is firstly combined with the colloidal gold marked with the antibody on the test paper 22 to form a colloidal gold-antigen-antibody compound, and then is combined with the antibody at the position of the detection line when chromatography is carried out to form a double-antibody sandwich structure, if the double-antibody sandwich structure is positive, the double-antibody sandwich structure shows red at the position of the detection line, if the double-antibody sandwich structure is negative, the double-antibody sandwich structure does not show color at the position of the detection line, and a red line appears at the position of the quality control line regardless of the positive or negative. The whole detection process is carried out in the same container, the sample does not need to be transferred, the sample is not easy to be polluted, and the detection accuracy is ensured; leakage is avoided, and cross infection is prevented; meanwhile, the operation steps are reduced, the operation difficulty is reduced, and people without related detection experience can quickly get on hand. The detected reagent, test paper 22 and swab are all left in the box, which is convenient for the centralized treatment of waste.

In one embodiment, as shown in fig. 3, the bottom surface of the reagent tank 13 is a downward slope inclined toward the thin half. The inclined slope structure is beneficial to the concentration of the reagent on the bottom of the slope, so that the eluted sample is more concentrated, the test paper 22 is beneficial to being contacted with the slope structure, and the titer and the detection accuracy of the sample are improved. As a variation, in another embodiment, as shown in fig. 4, the bottom surface of the reagent tank 13 is a compound surface formed by a downward slope surface inclined toward the thin half part and a plane surface connected to the end of the downward slope surface, i.e. a small section of the bottom surface at the tail of the reagent tank 13 is a plane surface, which is more beneficial to sample concentration and can save reagent usage. Of course, the specific shape of the reagent well 13 may be otherwise varied as desired.

In one embodiment, as shown in fig. 1-2, the reagent tank 13 is terminated with a ramp tank 3 for receiving reagent spilled therefrom. The ramp well 3 is shown with two adjacent parallel wells to provide a spatial buffer for the accidental spillage of reagent from the reagent well 13 and prevent further reagent spillage.

In one embodiment, as shown in fig. 1-2, the upper part of the reagent groove 13 is covered with a cover plate 2, the cover plate 2 is provided with a swab through hole 15 and a test paper through groove 16, the position of the swab through hole 15 corresponds to that of the reagent groove 13, and the position of the test paper through groove 16 corresponds to that of the slope groove 3; the upper surface of the cover plate 2 is flush with the inner surface of the thin half. The cover plate 2 can be integrally formed, reagent can be dripped into the reagent groove 13 through the test paper through groove 16, a swab with a sample is inserted into the reagent groove 13 through the swab through hole 15, after the box cover 8 is closed, the detection part or the head part of the test paper 22 penetrates through the test paper through groove 16 and then is immersed in the reagent groove 13, and the detection convenience and the position accuracy of the contact between the test paper 22 and the reagent are improved. The upper surface of the cover plate 2 is flush with the inner surface of the thin half part of the box body 1, so that the structure of the whole detection kit is more harmonious and beautiful.

In one embodiment, as shown in fig. 1-2, the swab through hole 15 and the test strip through slot 16 have a ridge (not shown, but visible) between them, the edge of which is chamfered. The bulge portion facilitates insertion of the swab, and the box cover 8 can be supported to prevent the reagent in the reagent groove 13 from overflowing due to the fact that the box cover 8 is deformed after being stressed and squeezed. The edge chamfer of the ridge prevents the swab from being scratched by the burr resulting in loss of sample from the swab.

In one embodiment, as shown in fig. 2, the bottom of the cover plate 2 has a protrusion 21 that is engaged with the reagent well 13, and the opposite side of the protrusion 21 is a second swab receiving well 20 adapted to receive the stem of a swab. The projections 21 are seamlessly engaged with the reagent tank 13, so that the liquid in the tank can be prevented from overflowing from the gap at the contact position of the cover plate 2 and the reagent tank 13. The second swab receiving channel 20 and the first swab receiving channel 19 together receive the shaft of the swab, increasing the contact area so that it does not slip out easily.

In one embodiment, as shown in fig. 2, a plurality of fixing posts 17 are fixedly arranged at the bottom of the cover plate 2, a plurality of fixing holes 14 are arranged at the periphery of the reagent tank 13, and each fixing post 17 is engaged with each fixing hole 14 in a one-to-one correspondence manner. The number of the fixing posts 17 and the fixing holes 14 shown in fig. 2 is four, and the posts are arranged in a rectangular shape, and the fixing points are provided around the reagent tank 13, so that the mounting is firm.

In one embodiment, as shown in fig. 1, at least one liquid barrier strip 5 is fixed to the inner surface of the thin half. In fig. 1, two sets of four liquid barriers 5 are shown. The liquid blocking strip 5 can diffuse the reagent which is prevented from accidentally overflowing to a distance, so that the pollution risk is reduced.

In one embodiment, as shown in fig. 1, the test strip fixing structure includes two pairs of test strip fixing buckles 12 and test strip limiting grooves 18, the test strip 22 is clamped in each pair of fixing buckles 12, and the tail portion of the test strip abuts against the test strip limiting grooves 18. This fixed structure may firmly hold the position of the test strip 22 against movement.

In one embodiment, as shown in fig. 1, the reagent holding structure further includes at least one reagent support bar 9, and the reagent support bar 9 is adapted to tilt the head of the reagent 22 so that the reagent 22 contacts the reagent in the reagent groove 13.

In one embodiment, the outer side wall of the box body 1 is provided with a clamping piece 4, and the inner side wall is provided with at least one clamping strip 6; the outer side edge of the box cover 8 is provided with a buckle 10, and the edge of the inner surface is provided with at least one clamping groove 7; the buckle 10 is suitable for being buckled with the clamping piece 4, and the clamping strips 6 are buckled with the clamping grooves 7 in a one-to-one correspondence mode. The box cover buckling structure has a multipoint stress structure, is uniformly stressed, and effectively prevents the test paper 22 from being crushed due to local stress.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the utility model, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims

1. The kit for detecting the new coronavirus antigen is characterized by comprising a box body (1), wherein one side of the box body (1) is hinged with a box cover (8) suitable for opening and closing; the kit body (1) comprises a thin half part and a thick half part, wherein a reagent groove (13) is formed in the inner bottom wall of the thick half part, and a first swab accommodating groove (19) is formed in the middle of the short side wall of the thick half part adjacent to the reagent groove (13); a test paper fixing structure and an observation window (11) are fixedly arranged on the box cover (8), a test paper (22) is fixed on the test paper fixing structure, the position of a sampling part of the test paper (22) corresponds to the position of the reagent groove (13), and the position of a color developing part of the test paper (22) corresponds to the position of the observation window (11); the first swab receiving channel (19) is adapted to receive a stem portion of a swab, and the reagent channel (13) is adapted to receive a sample portion of a swab.

2. The reagent kit for detecting a neocoronavirus antigen according to claim 1, wherein the bottom surface of the reagent well (13) is a downward slope surface inclined in the direction of the thin half.

3. The kit for detecting the antigen of the novel coronavirus according to claim 2, wherein the reagent tank (13) is connected with a slope tank (3) at the end for receiving the reagent overflowing therefrom.

4. The new coronavirus antigen detection kit according to claim 3, wherein a cover plate (2) covers the upper part of the reagent tank (13), the cover plate (2) is provided with a swab through hole (15) and a test strip through groove (16), the position of the swab through hole (15) corresponds to the reagent tank (13), and the position of the test strip through groove (16) corresponds to the slope groove (3); the upper surface of the cover plate (2) is flush with the inner surface of the thin half.

5. The new coronavirus antigen detection kit according to claim 4, wherein a bulge is arranged between the swab through hole (15) and the test strip through groove (16), and the edge of the bulge is chamfered.

6. The neocoronavirus antigen detection kit according to claim 4, wherein the bottom of the cover plate (2) has a protrusion (21) engaged with the reagent well (13), and the opposite surface of the protrusion (21) is a second swab receiving groove (20) adapted to receive the stem portion of the swab.

7. The reagent kit for detecting the antigen of the new coronavirus according to claim 4, wherein a plurality of fixing columns (17) are fixedly arranged at the bottom of the cover plate (2), a plurality of fixing holes (14) are formed in the periphery of the reagent tank (13), and the fixing columns (17) are correspondingly embedded with the fixing holes (14) one by one.

8. The kit for detecting neocoronaviruses antigen as claimed in claim 1, wherein at least one liquid barrier strip (5) is fixed on the inner surface of the thin half portion.

9. The reagent kit for detecting the antigen of the new coronavirus according to claim 1, wherein the test paper fixing structure comprises two pairs of test paper fixing buckles (12) and test paper limiting grooves (18), the test paper (22) is clamped in each pair of the fixing buckles (12), and the tail part of the test paper (22) abuts against the test paper limiting grooves (18).

10. The neocoronavirus antigen detection kit of claim 9, wherein said strip fixing structure further comprises at least one strip support bar (9), said strip support bar (9) being adapted to tilt the head of said strip (22).