CN216237052U - Cord blood stem cell separation bag - Google Patents
Cord blood stem cell separation bag Download PDFInfo
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- CN216237052U CN216237052U CN202122340520.5U CN202122340520U CN216237052U CN 216237052 U CN216237052 U CN 216237052U CN 202122340520 U CN202122340520 U CN 202122340520U CN 216237052 U CN216237052 U CN 216237052U
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- separation bag
- bag body
- stem cell
- cord blood
- separation
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Abstract
The utility model discloses a cord blood stem cell separation bag which comprises a separation bag body, wherein a wear-resistant layer is arranged on the side wall of the separation bag body, a heat insulation layer is arranged on the inner surface of the wear-resistant layer, a cavity is arranged on the inner surface of the heat insulation layer, an air guide pipe is arranged on the surface of the separation bag body, one end of the air guide pipe is connected with a connecting flange, the left end of the connecting flange is provided with an air heater through the air guide pipe, and the other end of the air guide pipe is connected with the cavity. According to the utility model, the air guide pipe is connected with the air heater through the connecting flange, the air heater heats gas and guides the gas into the cavity, the blood temperature is improved in a low-temperature environment, the separation efficiency is improved, the blood separation effect is prevented from being influenced by low temperature, the heat insulation layer has a good heat insulation effect, the heat loss is reduced, the wear-resistant layer can improve the service quality of the separation bag body, the anti-abrasion and anti-scraping effects are improved, and unnecessary loss caused by the breakage of the separation bag body is avoided.
Description
Technical Field
The utility model relates to the technical field of biology, in particular to a cord blood stem cell separation bag.
Background
Cord blood is blood that remains in the placenta and umbilical cord after the fetus is delivered, ligated and severed, and is typically discarded. Research in recent ten years shows that cord blood contains hematopoietic stem cells which can restore human hematopoietic and immune systems, and the cord blood can be used for hematopoietic stem cell transplantation to treat more than 80 diseases. Thus, cord blood has become an important source of hematopoietic stem cells.
The prior art has the following problems:
some existing cord blood stem cell separation bags lack a heating function, and blood is easy to coagulate in cold winter or low-temperature environments, so that the separation quality of stem cells is affected.
We have therefore proposed a cord blood stem cell separation bag which addresses the above disadvantages.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the defects in the prior art and provides a cord blood stem cell separation bag.
In order to achieve the purpose, the utility model adopts the following technical scheme: cord blood stem cell separation bag, including the separation bag body, separation bag body lateral wall is provided with the wearing layer, and the wearing layer internal surface is provided with the heat insulating layer, heat insulating layer internal surface is provided with the cavity, separation bag body surface is provided with the air duct, air duct expert one end is connected with flange, air heater is installed through the air duct to the flange left end, the air duct other end is connected with the cavity, temperature sensor is installed on separation bag body inner wall top.
Preferably, separation bag body internally mounted has the filter screen, the drain pipe is installed to separation bag body bottom, and the drain pipe bottom is connected with the filter box, be provided with thin filter core in the filter box, the stem cell bag is installed through the heat seal pipe to the filter box bottom, separation bag body surface mounting has the air pump, and the air pump passes through the connecting pipe and is connected with the filter box top.
Preferably, separation bag body bottom is provided with red blood cell bag, plasma bag respectively through the drain pipe, the drain pipe is provided with the ooff valve, separation bag body top is installed into the blood vessel.
Preferably, the top end of the separation bag body is provided with two groups of hanging rings through connecting rods.
Preferably, the screen is in the shape of an inverted "V".
Preferably, the liquid outlet pipe, the erythrocyte bag, the plasma bag and the stem cell bag are all made of transparent materials.
Preferably, the fine filter element is made of viscose fiber or polyester fiber material.
Compared with the prior art, the utility model has the beneficial effects that;
1. according to the utility model, the separation bag body has the heating and temperature insulation functions by the matching use of the cavity, the air heater, the connecting flange and the temperature insulation layer, the air guide pipe is connected with the air heater through the connecting flange, the air heater heats gas and guides the gas into the cavity, the blood temperature is improved in a low-temperature environment, the separation efficiency is improved, the low temperature is prevented from influencing the blood separation effect, the temperature insulation layer has a good temperature insulation effect, the heat loss is reduced, the wear-resistant layer can improve the use quality of the separation bag body, the wear-resistant and scratch-resistant effects are improved, and the unnecessary loss caused by the breakage of the separation bag body is avoided.
2. The utility model improves the stem cell separation effect by the matching use of a filter box, a filter screen, a fine filter element and an air pump, adds solution into blood to reduce viscosity, carries out centrifugal layering on umbilical cord blood by an ultracentrifuge, the separated blood enters the separation bag body through an inlet pipe, the filter screen carries out preliminary filtration to filter internal impurities, the umbilical cord blood after centrifugation is divided into three layers, the upper layer is plasma, the middle layer is umbilical cord blood hematopoietic stem cells, the lower layer is red blood cells, the red blood cell layer flows into the red blood cell bag by opening a switch valve of a liquid outlet pipe at the upper end of the red blood cell bag, then the switch valve above the filter box is opened, the stem cell layer is put into the filter box, the switch valve is closed, air is added into the filter box by starting the air pump to filter the stem cell layer in the filter box into the stem cell bag, the stem cell layer in the filter box is filtered by the fine filter element, the fine filter element can filter out a small part of residual white blood cells in the cord blood stem cells, and the purity of the stem cell extraction is improved.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments will be briefly described below
FIG. 1 is a schematic structural diagram of a cord blood stem cell separation bag according to the present invention;
FIG. 2 is an enlarged schematic view of cord blood stem cell separation bag A according to the present invention;
FIG. 3 is a schematic diagram of a cord blood stem cell separation bag filter screen according to the present invention.
Illustration of the drawings:
1. a separation bag body; 2. a wear layer; 3. an air heater; 4. a connecting flange; 5. an air duct; 6. a plasma bag; 7. a red blood cell bag; 8. an on-off valve; 9. a stem cell bag; 10. a fine filter element; 11. a filter box; 12. an air pump; 13. filtering with a screen; 14. a thermal insulation layer; 15. heat-sealing the tube; 16. hanging a ring; 17. (ii) a blood access vessel; 18. a temperature sensor; 19. a cavity; 20. a liquid outlet pipe.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in further detail with reference to the accompanying drawings in conjunction with the following detailed description. It should be understood that the description is intended to be exemplary only, and is not intended to limit the scope of the present invention. Moreover, in the following description, descriptions of well-known structures and techniques are omitted so as to not unnecessarily obscure the concepts of the present invention.
Referring to fig. 1-3, the cord blood stem cell separation bag comprises a separation bag body 1, wherein a wear-resistant layer 2 is arranged on the side wall of the separation bag body 1, a heat-insulating layer 14 is arranged on the inner surface of the wear-resistant layer 2, a cavity 19 is arranged on the inner surface of the heat-insulating layer 14, an air duct 5 is arranged on the surface of the separation bag body 1, one end of the air duct 5 is connected with a connecting flange 4, an air heater 3 is arranged at the left end of the connecting flange 14 through the air duct 5, the other end of the air duct 5 is connected with the cavity 19, a temperature sensor 18 is arranged at the top end of the inner wall of the separation bag body 1, a red blood cell bag 7 and a blood plasma bag 6 are respectively arranged at the bottom end of the separation bag body 1 through a liquid outlet pipe 20, a switch valve 8 is arranged on the liquid outlet pipe 20, and a blood inlet pipe 17 is arranged at the top end of the separation bag body 1.
In this embodiment: through setting up cavity 19, air heater 3, flange 4 and insulating layer 14's cooperation is used, make separation bag body 1 have the heating function that insulates against temperature, air duct 5 is connected with air heater 3 through flange 4, air heater 3 heats gas, leading-in cavity 19 is inside, raise blood temperature in low temperature environment, separation efficiency is improved, avoid low temperature to influence blood separation effect, insulating layer 14 plays good insulating effect, reduce thermal loss, wearing layer 2 can promote separation bag body 1 quality of use, promote the abrasionproof, prevent scraping the effect, avoid separation bag body 1 to break and cause unnecessary loss, temperature sensor 18 belongs to the common general knowledge in this field, only use it, do not reform transform, so no longer describe in detail control mode and circuit connection.
Concretely, 1 internally mounted of separation bag body has filter screen 13, drain pipe 20 is installed to 1 bottom of separation bag body, and the drain pipe 20 bottom is connected with and strains box 11, be provided with thin filter core 10 in straining box 11, strain box 11 bottom and install stem cell bag 9 through the heat seal pipe, 1 surface mounting of separation bag body has air pump 12, and air pump 12 passes through the connecting pipe and is connected with straining box 11 top, and filter screen 13 is "V" shape of falling, and drain pipe 20, red blood cell bag 7, plasma bag 6, stem cell bag 9 are made by transparent material, and thin filter core 10 is made by viscose fiber or polyester fiber material.
In this embodiment: through the matching use of the filter box 11, the filter screen 13, the fine filter element 10 and the air pump 12, the stem cell separation effect is improved, a solution is added into blood to reduce the viscosity, the cord blood is centrifugally layered by means of an ultracentrifuge, the separated blood enters the separation bag body 1 through the blood inlet pipe 17, the filter screen 13 performs preliminary filtration to filter internal impurities, the centrifuged cord blood is divided into three layers, the upper layer is blood plasma, the middle layer is cord blood hematopoietic stem cells, the lower layer is red blood cells, the red blood cell layer flows into the red blood cell bag 7 by opening the switch valve 8 of the liquid outlet pipe 20 at the upper end of the red blood cell bag 7, then the switch valve 8 above the filter box 11 is opened, the stem cell layer is put into the filter box 11, the switch valve 8 is closed, the air pump 12 is started to add air into the filter box 11, the stem cell layer in the filter box 11 is filtered into the stem cell bag 9, the stem cell layer in the filter box 11 is filtered by the fine filter element 10, the fine filter element 10 can filter out a small part of residual white blood cells in the cord blood stem cells, and the purity of the stem cell extraction is improved.
Specifically, the top end of the separation bag body 1 is provided with two groups of hanging rings 16 through connecting rods, and the hanging rings 16 are arranged.
In this embodiment: through setting up link 16, conveniently carry out the suspension type with separation bag body 1 and stew.
The working principle is as follows: during operation, the gas guide tube 5 is connected with the air heater 3 through the connecting flange 4, the air heater 3 heats gas, the gas is guided into the cavity 19, the blood temperature is improved in a low-temperature environment, the separation efficiency is improved, the blood separation effect is prevented from being influenced by low temperature, the heat insulation layer 14 has a good heat insulation effect, the heat loss is reduced, the service quality of the separation bag body 1 can be improved through the wear-resistant layer 2, the wear-resistant and scratch-resistant effects are improved, unnecessary loss caused by breakage of the separation bag body 1 is avoided, solution is added into the blood, the viscosity is reduced, the umbilical cord blood is centrifugally layered by means of an ultracentrifuge, the separated blood enters the separation bag body 1 through the blood inlet tube 17, the filter screen 13 performs primary filtration to filter internal impurities, the centrifuged umbilical cord blood is divided into three layers, the upper layer is blood plasma, the middle layer is an umbilical cord blood hematopoietic stem cell, and the lower layer is red blood cells, through the on-off valve 8 of opening the drain pipe 20 on the upper end of the erythrocyte bag 7, the erythrocyte layer flows into the erythrocyte bag 7, the on-off valve 8 above the filter box 11 is opened again, the stem cell layer is put into the filter box 11, the on-off valve 8 is closed, through starting the air pump 12, the air is added into the filter box 11, the stem cell layer in the filter box 11 is filtered into the stem cell bag 9, the stem cell layer in the filter box 11 is filtered through the fine filter element 10, the fine filter element 10 can filter out the residual small part of white blood cells in the umbilical cord blood stem cells, and the purity of stem cell extraction is improved.
It is to be understood that the above-described embodiments of the present invention are merely illustrative of or explaining the principles of the utility model and are not to be construed as limiting the utility model. Therefore, any modification, equivalent replacement, improvement and the like made without departing from the spirit and scope of the present invention should be included in the protection scope of the present invention. Further, it is intended that the appended claims cover all such variations and modifications as fall within the scope and boundaries of the appended claims or the equivalents of such scope and boundaries.
Claims (7)
1. Cord blood stem cell separation bag, including separation bag body (1), its characterized in that, separation bag body (1) lateral wall is provided with wearing layer (2), and wearing layer (2) internal surface is provided with heat insulating layer (14), heat insulating layer (14) internal surface is provided with cavity (19), separation bag body (1) surface is provided with air duct (5), air duct (5) lead to one end and are connected with flange (4), air heater (3) are installed through air duct (5) to flange (4) left end, the air duct (5) other end is connected with cavity (19), temperature sensor (18) are installed on separation bag body (1) inner wall top.
2. The cord blood stem cell separation bag of claim 1, characterized in that, separation bag body (1) internally mounted has filter screen (13), drain pipe (20) is installed to separation bag body (1) bottom, and drain pipe (20) bottom is connected with cartridge (11), be provided with fine filter core (10) in cartridge (11), dry cell bag (9) is installed through heat seal pipe (15) in cartridge (11) bottom, separation bag body (1) surface mounting has air pump (12), and air pump (12) are connected with cartridge (11) top through the connecting pipe.
3. The cord blood stem cell separation bag according to claim 2, wherein the bottom end of the separation bag body (1) is provided with a red blood cell bag (7) and a plasma bag (6) through a liquid outlet pipe (20), the liquid outlet pipe (20) is provided with a switch valve (8), and the top end of the separation bag body (1) is provided with a blood inlet pipe (17).
4. Cord blood stem cell separation bag according to claim 1, characterized in that the top end of the separation bag body (1) is provided with two groups of hanging rings (16) through connecting rods, and the hanging rings (16) are arranged.
5. Cord blood stem cell separation bag according to claim 2, characterized in that the sieve (13) is in the shape of an inverted "V".
6. The cord blood stem cell separation bag of claim 2, wherein the outlet tube (20), the red blood cell bag (7), the plasma bag (6) and the stem cell bag (9) are made of transparent materials.
7. Cord blood stem cell separation bag according to claim 2, characterized in that the fine filter element (10) is made of viscose or polyester fiber material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122340520.5U CN216237052U (en) | 2021-09-24 | 2021-09-24 | Cord blood stem cell separation bag |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122340520.5U CN216237052U (en) | 2021-09-24 | 2021-09-24 | Cord blood stem cell separation bag |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216237052U true CN216237052U (en) | 2022-04-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122340520.5U Active CN216237052U (en) | 2021-09-24 | 2021-09-24 | Cord blood stem cell separation bag |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216237052U (en) |
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2021
- 2021-09-24 CN CN202122340520.5U patent/CN216237052U/en active Active
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