CN216236972U - Fermentation cylinder for bio-pharmaceuticals convenient to sample - Google Patents

Fermentation cylinder for bio-pharmaceuticals convenient to sample Download PDF

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Publication number
CN216236972U
CN216236972U CN202122770554.8U CN202122770554U CN216236972U CN 216236972 U CN216236972 U CN 216236972U CN 202122770554 U CN202122770554 U CN 202122770554U CN 216236972 U CN216236972 U CN 216236972U
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sampling
main body
fermentation tank
tank
fermentation
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CN202122770554.8U
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魏庚辉
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Chengdu Daoheer Pharmaceutical Technology Co ltd
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Chengdu Daoheer Pharmaceutical Technology Co ltd
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Abstract

The utility model relates to a fermentation tank for bio-pharmaceuticals, which is convenient for sampling and comprises a fermentation tank main body and a sampling tank, wherein a stirring motor is arranged at the center of the top of the fermentation tank main body; the sampling tank is communicated with the lower end side wall of the fermentation tank main body, a movable sealing plate is arranged at the communication position of the fermentation tank main body and the sampling tank, an operating rod is perpendicularly connected to one side of the sealing plate towards the sampling tank, the operating rod penetrates through the sampling tank to extend to the outside, the sampling tank is a closed tank body, a sampling port is arranged at the bottom of the sampling tank, and an observation window is further arranged above the sampling tank and on the side wall of the fermentation tank main body. The utility model facilitates the observation of the sampling process and takes the appropriate amount of sample.

Description

Fermentation cylinder for bio-pharmaceuticals convenient to sample
Technical Field
The utility model relates to the technical field of fermentation tanks, in particular to a fermentation tank for bio-pharmaceuticals, which is convenient for sampling.
Background
At present, most medicines contain organic matter components which can be obtained only by microbial fermentation, so that a fermentation tank is used in the production of the medicines at present, and the fermentation tank is a device for microbial fermentation and can produce organic matters such as antibiotics, amino acids, organic acids, vitamins and the like.
During fermentation cylinder preparation for the bio-pharmaceuticals of prior art, in order to ensure that the medicine is taken after fully fermenting completely to control the pharmacy progress, need carry out the blowing sample through getting the material mouth, judge the pharmacy progress with this. However, in the existing fermentation tank, the material taking port is large during material taking, raw material waste is easily caused during sampling, and a small amount of external gas is generated in the fermentation tank during material taking, so that the fermentation progress of the medicine is polluted or influenced.
SUMMERY OF THE UTILITY MODEL
The utility model provides a fermentation tank for bio-pharmaceuticals, which is convenient for sampling.
In order to achieve the purpose, the technical scheme adopted by the utility model is as follows:
a fermentation tank for bio-pharmaceuticals convenient for sampling comprises a fermentation tank main body and a sampling tank, wherein a stirring motor is arranged at the center of the top of the fermentation tank main body, a rotating shaft is fixedly connected to the lower end of a motor shaft of the stirring motor, stirring blades are arranged on the rotating shaft, a feeding hole is communicated with the side wall of the top of the fermentation tank main body, an air inlet pipe is also communicated with the top of the fermentation tank main body, a gas one-way valve is arranged in the air inlet pipe, and a discharging pipe is communicated with the center of the bottom of the fermentation tank main body;
the sampling tank is communicated with the lower end side wall of the fermentation tank main body, a movable sealing plate is arranged at the communication position of the fermentation tank main body and the sampling tank, an operating rod is perpendicularly connected to one side of the sealing plate towards the sampling tank, the operating rod penetrates through the sampling tank to extend to the outside, the sampling tank is a closed tank body, a sampling port is arranged at the bottom of the sampling tank, and an observation window is further arranged above the sampling tank and on the side wall of the fermentation tank main body.
Furthermore, a pipe support is arranged on a passage of the operating rod in the sampling tank, and the operating rod can penetrate through the inner cavity of the pipe support in a matching mode and can slide horizontally.
Furthermore, the top of observation window is connected with the apron through the hinge rotation, but the apron adaptation covers the observation window.
Furthermore, the observation window is made of glass.
Furthermore, a support is fixedly connected to the bottom of the fermentation tank main body.
Furthermore, the gas flow direction of the gas one-way valve is from the upper end to the lower end in a one-way flow mode.
Furthermore, the feed inlet, the air inlet pipe and the sampling port are all provided with adaptive sealing screw caps.
Furthermore, a shaft seal is arranged at the joint of the stirring motor and the fermentation tank main body, and a sealing rubber sleeve is arranged at the joint of the operating rod and the sampling tank.
Further, the tapping pipe is equipped with a pipe valve.
Compared with the prior art, the utility model has the following beneficial effects:
1. the utility model is convenient for observing the sampling process, and takes a proper amount of medicine samples according to the requirements, thereby avoiding waste;
2. the utility model ensures that the sampling process is relatively closed, ensures that the medicine in the fermentation tank is not polluted by bacteria or microorganisms in the air, and does not influence the fermentation progress;
3. the utility model can prevent the incompletely fermented gas in the fermentation tank from escaping to the external environment to cause pollution.
Drawings
FIG. 1 is a front sectional view of the present invention;
FIG. 2 is a schematic partial perspective view of a sampling tank and a viewing window;
FIG. 3 is an enlarged view of the structure of FIG. 1 at A according to the present invention;
FIG. 4 is a sectional view showing the state where the sealing plate is pushed into the main body of the fermenter to take a sample;
the attached drawings are as follows: 1-fermentation tank main body, 2-stirring motor, 3-rotating shaft, 4-stirring blade, 5-air inlet pipe, 6-gas one-way valve, 7-feeding port, 8-discharging pipe, 9-support, 10-observation window, 11-cover plate, 12-sampling tank, 13-sealing plate, 14-operating rod, 15-pipe support and 16-sampling port.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to examples and accompanying drawings, and the exemplary embodiments and descriptions thereof are only used for explaining the present invention and are not meant to limit the present invention.
Example one
As shown in fig. 1, 2, 3 and 4, the fermentation tank for bio-pharmaceuticals convenient to sample disclosed by the utility model comprises a fermentation tank main body 1 and a sampling tank 12, wherein a stirring motor 2 is arranged at the center of the top of the fermentation tank main body 1, a rotating shaft 3 is fixedly connected to the lower end of a motor shaft of the stirring motor 2, a stirring blade 4 is arranged on the rotating shaft 3, a feeding hole 7 is communicated with the side wall of the top of the fermentation tank main body 1, an air inlet pipe 5 is also communicated with the top of the fermentation tank main body 1, a gas one-way valve 6 is arranged in the air inlet pipe 5, and a discharging pipe 8 is communicated with the center of the bottom of the fermentation tank main body 1.
Sampling tank 12 switches on in the lower extreme lateral wall of fermentation cylinder main part 1, and fermentation cylinder main part 1 is equipped with mobilizable closing plate 13 with the intercommunication department of sampling tank 12, closing plate 13 is connected with action bars 14 towards sampling tank 12 one side perpendicularly, action bars 14 pass sampling tank 12 and extend the outside, sampling tank 12 is airtight jar body, and sampling tank 12 bottom is equipped with sample connection 16, sampling tank 12 top, fermentation cylinder main part 1 lateral wall still are provided with observation window 10.
A pipe bracket 15 is arranged in the sampling tank 12 and on the passage of the operating rod 14, and the operating rod 14 can be adapted to pass through the inner cavity of the pipe bracket 15 and horizontally slide. The pipe bracket 15 is used for providing stable limit support for the operating rod 14, and ensures that an operator can stably move horizontally when pushing the operating rod 14.
The upper side of the observation window 10 is rotatably connected with a cover plate 11 through a hinge, and the cover plate 11 can be adapted to cover the observation window 10. In order to prevent the influence of light and direct temperature on the medicines in the fermentation process, the cover plate 11 covers the observation window 10 in the conventional case and is opened only during sampling so as to facilitate observation.
The observation window 10 is made of glass.
The bottom of the fermentation tank main body 1 is fixedly connected with a support 9.
The gas one-way valve 6 flows in a one-way mode from the upper end to the lower end. The gas inlet pipe 5 facilitates the transportation of the reaction gas to the interior of the fermenter body 1, and the gas check valve 6 prevents the gas in the fermenter body 1 from escaping to the outside environment.
The feed inlet 7, the air inlet pipe 5 and the sampling port 16 are all provided with adaptive sealing screw caps.
And a shaft seal is arranged at the joint of the stirring motor 2 and the fermentation tank main body 1, and a sealing rubber sleeve is arranged at the joint of the operating rod 13 and the sampling tank 12. The shaft seal is a sealing device which can prevent gas and fluid from leaking at the joint, and the sealing rubber sleeve can also increase the sealing effect between the relatively movable operating rod 13 and the sampling tank 12.
The discharge pipe 8 is equipped with a pipe valve for controlling the opening and closing of the discharge pipe 8.
Example two
On the basis of the first embodiment, the embodiment provides a specific implementation process of the fermentation tank for the bio-pharmaceuticals, which is convenient for sampling.
The specific implementation principle flow is as follows:
when the sample needs to be taken to know the progress of the drug fermentation, the cover plate is opened, and the operating rod is held by hand to push the sealing plate into the fermentation tank main body. Since the drug is accumulated in the main body of the fermentation tank, the drug flows into the sampling tank through the gap around the sealing plate after the sealing plate is pushed in. The degree of pushing the sealing plate can be seen through the observation window, and the flow rate of the medicine flowing into the sampling tank is manually adjusted to determine the proper sampling amount. After the sampling is finished, the operating rod is pulled out outwards, and the sealing plate plugs the hole between the fermentation tank main body and the sampling tank. At this time, the sealing screw cap at the sampling port is unscrewed, and the vessel is used for receiving the sample, thereby completing the operation.
The present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof, and it is therefore intended that all such changes and modifications as fall within the true spirit and scope of the utility model be considered as within the following claims.

Claims (9)

1. The utility model provides a fermentation cylinder for bio-pharmaceuticals convenient to sample which characterized in that: the fermentation tank comprises a fermentation tank main body and a sampling tank, wherein a stirring motor is arranged in the center of the top of the fermentation tank main body, a rotating shaft is fixedly connected to the lower end of a motor shaft of the stirring motor, stirring blades are arranged on the rotating shaft, a feeding hole is communicated with the side wall of the top of the fermentation tank main body, an air inlet pipe is also communicated with the top of the fermentation tank main body, a gas one-way valve is arranged in the air inlet pipe, and a discharging pipe is communicated with the center of the bottom of the fermentation tank main body;
the sampling tank is communicated with the lower end side wall of the fermentation tank main body, a movable sealing plate is arranged at the communication position of the fermentation tank main body and the sampling tank, an operating rod is perpendicularly connected to one side of the sealing plate towards the sampling tank, the operating rod penetrates through the sampling tank to extend to the outside, the sampling tank is a closed tank body, a sampling port is arranged at the bottom of the sampling tank, and an observation window is further arranged above the sampling tank and on the side wall of the fermentation tank main body.
2. The fermenter for biopharmaceutical use of claim 1, wherein: a pipe support is arranged in the sampling tank and on a passage of the operating rod, and the operating rod can penetrate through an inner cavity of the pipe support in a matching mode and can slide horizontally.
3. The fermenter for biopharmaceutical use of claim 1, wherein: the top of observation window is connected with the apron through the hinge rotation, but the apron adaptation covers the observation window.
4. The fermenter for biopharmaceutical use of claim 3, wherein: the observation window is made of glass.
5. The fermenter for biopharmaceutical use of claim 1, wherein: the bottom of the fermentation tank main body is fixedly connected with a support.
6. The fermenter for biopharmaceutical use of claim 1, wherein: the air flow direction of the air one-way valve is from the upper end to the lower end in a one-way flow mode.
7. The fermenter for biopharmaceutical use of claim 1, wherein: the feed inlet, the air inlet pipe and the sampling port are all provided with adaptive sealing screw caps.
8. The fermenter for biopharmaceutical use of claim 1, wherein: the joint of the stirring motor and the fermentation tank main body is provided with a shaft seal, and the joint of the operating rod and the sampling tank is provided with a sealing rubber sleeve.
9. The fermenter for biopharmaceutical use of claim 1, wherein: the discharge pipe is equipped with a pipe valve.
CN202122770554.8U 2021-11-12 2021-11-12 Fermentation cylinder for bio-pharmaceuticals convenient to sample Active CN216236972U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202122770554.8U CN216236972U (en) 2021-11-12 2021-11-12 Fermentation cylinder for bio-pharmaceuticals convenient to sample

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202122770554.8U CN216236972U (en) 2021-11-12 2021-11-12 Fermentation cylinder for bio-pharmaceuticals convenient to sample

Publications (1)

Publication Number Publication Date
CN216236972U true CN216236972U (en) 2022-04-08

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116814379A (en) * 2023-08-29 2023-09-29 哈尔滨葵花药业有限公司 Fermentation equipment is used in lactobacillus reuteri culture
CN117004479A (en) * 2023-08-10 2023-11-07 河北蔺氏盛泰药业有限公司 Raw material fusion uniform fermentation equipment for malt processing

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117004479A (en) * 2023-08-10 2023-11-07 河北蔺氏盛泰药业有限公司 Raw material fusion uniform fermentation equipment for malt processing
CN117004479B (en) * 2023-08-10 2024-01-26 河北蔺氏盛泰药业有限公司 Raw material fusion uniform fermentation equipment for malt processing
CN116814379A (en) * 2023-08-29 2023-09-29 哈尔滨葵花药业有限公司 Fermentation equipment is used in lactobacillus reuteri culture

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